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Id: biblio-1047375
Autor: Li, Shanshan; Qin, Kun; Li, Huaying; Guo, Jin; Li, Dejin; Liu, Fang; Tan, Zhilei; Yan, Wei; Qu, Shuling; Zhao, Huabing.
Título: Cloning and characterisation of four catA genes located on the chromosome and large plasmid of Pseudomonas putida ND6
Fonte: Electron. j. biotechnol;34:83-90, july. 2018. tab, ilus, graf.
Idioma: en.
Projeto: Tianjin Research Program of Application Foundation and Advanced Technology; . National Natural Science Foundation of China.
Resumo: Background: Although the functional redundancy of catechol 1,2-dioxygenase (C12O) genes has been reported in several microorganisms, limited enzymes were characterised, let alone the advantage of the coexistence of the multiple copies of C12O genes. Results: In this study, four novel C12O genes, designated catA, catAI, catAII and catAIII, in the naphthalene-degrading strain Pseudomonas putida ND6, were cloned and characterised. Phylogenetic analysis of their deduced amino acid sequences revealed that the four C12O isozymes each formed independent subtrees, together with homologues from other organisms. All four enzymes exhibited maximum activity at pH 7.4 and higher activity in alkaline than in acidic conditions. Furthermore, CatA, CatAI and CatAIII were maximally active at a temperature of 45°C, whereas a higher optimum temperature was observed for CatAII at a temperature of 50°C. CatAI exhibited superior temperature stability compared with the other three C12O isozymes, and kinetic analysis indicated similar enzyme activities for CatA, CatAI and CatAII, whereas that of CatAIII was lower. Significantly, among metal ions tested, only Cu2+ substantially inhibited the activity of these C12O isozymes, thus indicating that they have potential to facilitate bioremediation in environments polluted with aromatics in the presence of metals. Moreover, gene expression analysis at the mRNA level and determination of enzyme activity clearly indicated that the redundancy of the catA genes has increased the levels of C12O. Conclusion: The results clearly imply that the redundancy of catA genes increases the available amount of C12O in P. putida ND6, which would be beneficial for survival in challenging environments.
Descritores: Pseudomonas putida/enzimologia
Pseudomonas putida/genética
Catecol 1,2-Dioxigenase/genética
-Temperatura
Biodegradação Ambiental
Clonagem Molecular
Catecol 1,2-Dioxigenase/análise
Catecol 1,2-Dioxigenase/metabolismo
Genes Bacterianos
Concentração de Íons de Hidrogênio
Isoenzimas
Metais
Responsável: CL1.1 - Biblioteca Central


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Texto completo SciELO Brasil
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Id: biblio-1089830
Autor: Moreira, Fernando César; Jacob, Helder Baldi; Vaz, Luis Geraldo; Guastaldi, Antonio Carlos.
Título: Effect of Yd: YAG laser irradiation on the shear bond strength of orthodontic metal brackets
Fonte: Dental press j. orthod. (Impr.);25(1):28-35, Jan.-Feb. 2020. tab, graf.
Idioma: en.
Resumo: ABSTRACT Objective: The purpose of this study was to evaluate the effect of the Yd:YAG laser irradiation on orthodontic bracket base surface. Shear bond strength (SBS) values and sites of the bonding failure interfaces were quantified. Methods: Brackets were divided into two groups: OP (One Piece - integral sandblast base) and OPL (One Piece - laser irradiation). The brackets were randomly bonded on an intact enamel surface of 40 bovine incisors. The SBS tests were carry out using a universal test machine. A stereomicroscopy was used to evaluate the adhesive remnant index (ARI), and surface characterization was performed by scanning electron microscopy (SEM). Student's t-test was used to compare the SBS between the two groups (p< 0.05). Frequencies and chi-square analysis were applied to evaluate the ARI scores. Results: OPL group showed higher value (p< 0.001) of SBS than OP group (43.95 MPa and 34.81 MPa, respectively). ARI showed significant difference (p< 0.001) between OPL group (ARI 0 = 100%) and OP group (ARI 0 = 15%). SEM showed a higher affinity between the adhesive and the irradiated laser base surface. Conclusions: Yd:YAG laser irradiation on bracket base increased SBS values, showing that bonding failure occurs at the enamel/adhesive interface. Laser-etched bracket base may be used instead of conventional bases in cases where higher adhesion is required, reducing bracket-bonding failure.

RESUMO Objetivo: O objetivo do presente estudo foi avaliar o efeito da aplicação do laser Yd:YAG sobre a superfície metálica da base de braquetes ortodônticos, a resistência da colagem ao cisalhamento (RU) e os locais das falhas nas interfaces adesivas. Métodos: Os braquetes foram divididos em dois grupos, de acordo com o tipo de base: OP (One Piece - monobloco, base jateada) e OPL (One Piece - monobloco, base irradiada a laser). Foram selecionados 40 incisivos bovinos hígidos para a colagem de braquetes na superfície do esmalte. Os testes de RU foram realizados por meio de uma máquina de ensaio universal EMIC DL1000. O Índice de Adesivo Remanescente (ARI) e a caracterização das superfícies foram realizados empregando-se estereomicroscópio e microscópio eletrônico de varredura (MEV). O teste t de Student foi aplicado para comparar a RU entre os dois grupos (p< 0,05). O ARI foi avaliado por meio da análise de Frequência e teste do Qui-quadrado. Resultados: O grupo OPL obteve maiores valores de RU (p<0,001) do que o grupo OP (43,95 MPa e 34,81 MPa, respectivamente), e o ARI obteve diferença significativa (p<0,001) entre os grupos OPL (ARI 0 = 100%) e OP (ARI 0 = 15%). A análise proveniente do MEV mostrou alta interação adesiva entre a resina e a superfície metálica da base irradiada pelo feixe de laser. Conclusões: A irradiação com laser Yd:YAG sobre a superfície da base de braquetes metálicos aumentou os valores da RU, demonstrando que as falhas adesivas ocorreram na interface esmalte/adesivo. O uso de braquetes modificados com irradiação a laser pode ser adotado como alternativa aos braquetes com bases convencionais nos casos em que uma maior retentividade for requerida para reduzir as falhas de adesividade.
Descritores: Colagem Dentária
Braquetes Ortodônticos
Lasers de Estado Sólido
-Propriedades de Superfície
Bovinos
Resistência ao Cisalhamento
Metais
Limites: Humanos
Animais
Responsável: BR1.1 - BIREME


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Id: biblio-1087876
Autor: Valera-Cornejo, Diego; García-Roa, Marlon; Ramírez-Neria, Paulina; Villalpando-Gómez, Yolanda; Romero-Morales, Verónica; García-Franco, Renata.
Título: Papel de distintas técnicas de imagen para identificar y localizar cuerpos extraños intraoculares relacionados con trauma ocular abierto: reporte de tres casos y revisión de la literatura / The role of various imaging techniques in identifying and locating intraocular foreign bodies related to open-globe injury: three case reports and literature review
Fonte: Medwave;20(1):e7772, 2020.
Idioma: en; es.
Resumo: ANTECEDENTES La ubicación precisa de un cuerpo extraño intraocular es crucial para el manejo de pacientes con trauma ocular abierto. La tomografía computarizada se usa habitualmente para detectar su ubicación en el segmento posterior. Reportamos tres casos con diferentes cuerpos extraños intraoculares en el segmento posterior, que fueron localizados con precisión mediante la tomografía computarizada y ecografía modo B. PRESENTACIÖN DEL CASO Presentamos tres casos con diferentes mecanismos de trauma, tipos de cuerpo extraño intraocular, síntomas clínicos y pronóstico visual. La tomografía computarizada determinó la ubicación exacta de todos los cuerpos extraños intraoculares en el segmento posterior. El ultrasonido modo B se realizó en un paciente con un cuerpo extraño intraocular no metálico. El primer caso tuvo una lesión ocular perforante con un cuerpo extraño intraorbitario; el caso dos y el caso tres presentaron diferentes tipos de cuerpos extraños intraoculares con pronóstico diferente. El manejo y el pronóstico fue distinto en todos los casos; todos se manejaron con éxito. La ubicación exacta de los cuerpos extraños intraoculares utilizando las diferentes modalidades de diagnóstico es importante en estos pacientes. Estos casos sirven como recordatorio de que el uso adecuado de las pruebas de imagen es indispensable en el contexto de un cuerpo extraño intraocular relacionado con trauma ocular abierto. CONCLUSIÓN Las diferentes técnicas de imágenes son muy importantes para la detección de un cuerpo extraño intraocular. La tomografía computarizada es una de las modalidades de imagen más simple y efectiva para la localización de cuerpos extraños intraoculares relacionadas con trauma ocular abierto.

BACKGROUND: Determining the precise location of intraocular foreign bodies is crucial for the management of patients with open-globe injury. Computed tomography is the most common method for detecting intraocular foreign bodies in the posterior segment. In this article, we describe three cases of open-globe injury with different types of intraocular foreign bodies in the posterior segment that were accurately located using computed tomography scans and B-scan ultrasonography. CASE PRESENTATION: Each of the three cases of open-globe injury described in this report had different types of ocular trauma, clinical symptoms, and intraocular foreign bodies. Computed tomography scans showed the exact location of the intraocular foreign bodies in the posterior segment in two of the three cases. A B-scan ultrasound was used to determine the location of a non-metallic intraocular foreign body in the third case. All three patients had intraocular foreign bodies, and one of them had an additional orbital foreign body. Case 1 had a perforating eye injury with the additional intraorbital foreign body; Cases 2 and Case 3 had different types of intraocular foreign bodies and prognoses. Various treatment approaches were used, ranging from observation to surgery, depending on the location of the intraocular foreign bodies, and all cases were successfully managed. These three cases show that proper use of various types of imaging tests is indispensable in the context of an intraocular foreign body related to open-globe injury. CONCLUSION: Imaging techniques are crucial for the detection of an intraocular foreign body, and computed tomography is one of the simplest and most useful, especially in cases of open-globe injury.
Descritores: Tomografia Computadorizada por Raios X
Ferimentos Oculares Penetrantes/diagnóstico por imagem
Corpos Estranhos no Olho/diagnóstico por imagem
Ultrassonografia
-Plásticos
Ferimentos por Arma de Fogo/complicações
Ferimentos por Arma de Fogo/diagnóstico por imagem
Traumatismos por Explosões/complicações
Traumatismos por Explosões/diagnóstico por imagem
Imageamento por Ressonância Magnética
Radiografia
Ferimentos Oculares Penetrantes/complicações
Corpos Estranhos no Olho/etiologia
Vidro
Metais
Limites: Humanos
Masculino
Adolescente
Adulto
Tipo de Publ: Relatos de Casos
Revisão
Responsável: CL1.1 - Biblioteca Central


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Id: biblio-1093005
Autor: García, Juan Daniel Díaz; Arceo, Emmanuel.
Título: Renal damage associated with heavy metals: review work / Daño renal asociado a metales pesados: trabajo de revisión
Fonte: Rev. colomb. nefrol. (En línea);5(1):45-53, Jan.-June 2018. tab, graf.
Idioma: en.
Resumo: Abstract Catheter-associated infection is an entity with multiple complications, a condition that alters the quality of life of all patients Chronic kidney disease (CKD) represents an important health problem in the entire global population, where knowledge of the environmental factors associated with this disease is currently essential for its prevention. Several heavy metals are recognized, including Cadmium (Cd), Lead (Pb), Arsenic (As) and Mercury (Hg), which are clearly associated with renal damage and progression of CKD. Studies in animals and humans primarily demonstrate a clear association between exposure to these metals and the presence of chronic renal damage, where the pathophysiology of each of these metals is important in understanding the mechanism of renal damage. The present review aims to analyze the pathophysiology and clinical manifestations of the nephrotoxicity associated with these metals, as well as the different studies in both humans and animals that have been performed.

Resumen La enfermedad renal crónica (ERC) representa un importante problema de salud en todo el globo. Actualmente, es esencial para su prevención el conocimiento de los factores ambientales asociados con la enfermedad. Se reconocen diversos metales pesados, entre los que destacan el cadmio (Cd), plomo (Pb), arsénico (As) y mercurio (Hg), que están claramente asociados con la lesión renal y la progresión de la ERC. Estudios en animales y humanos demuestran, principalmente, una clara asociación entre la exposición a estos metales y la presencia de daño renal crónico, donde la fisiopatologia de cada uno de ellos es importante para entender el mecanismo de daño renal. La presente revisión tiene como objetivo analizar, tanto la fisiopatología y manifestaciones clínicas de la nefrotoxicidad asociada a dichos metales, como los diferentes estudios que se han realizado en humanos y animales.
Descritores: Metais Pesados
Insuficiência Renal Crônica
-Arsênio
Cádmio
Necrose Tubular Aguda
Chumbo
Mercúrio
Metais
Limites: Humanos
Masculino
Feminino
Tipo de Publ: Revisão
Responsável: CO661.9


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Texto completo SciELO Chile
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Id: biblio-950788
Autor: Chen, Peng; Wang, Yuxia; Yan, Lei; Wang, Yiqing; Li, Suyue; Yan, Xiaojuan; Wang, Ningbo; Liang, Ning; Li, Hongyu.
Título: Feasibility of biohydrogen production from industrial wastes using defined microbial co-culture
Fonte: Biol. Res;48:1-8, 2015. ilus, graf, tab.
Idioma: en.
Projeto: Gansu Province Science Foundation for Distinguished Young Scholars; . Longyuan Support Project for Young Creative Talents; . Technology Program of Gansu Province; . Technology Program of Lanzhou City; . NationalNaturalScience Foundation of China.
Resumo: BACKGROUND: The development of clean or novel alternative energy has become a global trend that will shape the future of energy. In the present study, 3 microbial strains with different oxygen requirements, including Clostridium acetobutylicum ATCC 824, Enterobacter cloacae ATCC 13047 and Kluyveromyces marxianus 15D, were used to construct a hydrogen production system that was composed of a mixed aerobic-facultative anaerobic-anaerobic consortium. The effects of metal ions, organic acids and carbohydrate substrates on this system were analyzed and compared using electrochemical and kinetic assays. It was then tested using small-scale experiments to evaluate its ability to convert starch in 5 L of organic wastewater into hydrogen. For the one-step biohydrogen production experiment, H1 medium (nutrient broth and potato dextrose broth) was mixed directly with GAM broth to generate H2 medium (H1 medium and GAM broth). Finally, Clostridium acetobutylicum ATCC 824, Enterobacter cloacae ATCC 13047 and Kluyveromyces marxianus 15D of three species microbial co-culture to produce hydrogen under anaerobic conditions. For the two-step biohydrogen production experiment, the H1 medium, after cultured the microbial strains Enterobacter cloacae ATCC 13047 and Kluyveromyces marxianus 15D, was centrifuged to remove the microbial cells and then mixed with GAM broth (H2 medium). Afterward, the bacterial strain Clostridium acetobutylicum ATCC 824 was inoculated into the H2 medium to produce hydrogen by anaerobic fermentation. RESULTS: The experimental results demonstrated that the optimum conditions for the small-scale fermentative hydrogen production system were at pH 7.0, 35°C, a mixed medium, including H1 medium and H2 medium with 0.50 mol/L ferrous chloride, 0.50 mol/L magnesium sulfate, 0.50 mol/L potassium chloride, 1% w/v citric acid, 5% w/v fructose and 5% w/v glucose. The overall hydrogen production efficiency in the shake flask fermentation group was 33.7 mL/h-1.L-1, and those the two-step and the one-step processes of the small-scale fermentative hydrogen production system were 41.2 mLVh-1.L-1 and 35.1 mL/h-1.L-1, respectively. CONCLUSION: Therefore, the results indicate that the hydrogen production efficiency of the two-step process is higher than that of the one-step process.
Descritores: Fermentação/fisiologia
Consórcios Microbianos/fisiologia
Hidrogênio/metabolismo
Resíduos Industriais
-Amido/metabolismo
Fatores de Tempo
Kluyveromyces/metabolismo
Ácidos Carboxílicos/metabolismo
Estudos de Viabilidade
Enterobacter cloacae/metabolismo
Técnicas de Cocultura
Clostridium acetobutylicum/metabolismo
Condutividade Elétrica
Interações Microbianas/fisiologia
Energia Renovável
Águas Residuárias/análise
Hidrogênio/análise
Íons/metabolismo
Metais/metabolismo
Tipo de Publ: Research Support, Non-U.S. Gov't
Responsável: CL1.1 - Biblioteca Central


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Texto completo SciELO Brasil
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Id: biblio-950207
Autor: Fonseca, Francisco Antonio Helfenstein.
Título: Persistent Inflammatory Activity in Blood Cells and Artery Tissue from Patients with Previous Bare Metal Stent / Atividade Inflamatória Persistente em Células Circulantes e Tecido Arterial de Pacientes com Stent Convencional Prévio
Fonte: Arq. bras. cardiol;111(2):142-143, Aug. 2018.
Idioma: en.
Descritores: Stents
Reestenose Coronária
-Artérias
Células Sanguíneas
Resultado do Tratamento
Metais
Limites: Humanos
Tipo de Publ: Comentário
Editorial
Responsável: BR1.1 - BIREME


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Id: biblio-842504
Autor: Reynoso, Exequiel; Carrascosa, Patricia; Capuñay, Carlos; Rasumoff, Alejandro; Vallejos, Javier; Carpio, Jimena; Lago, Karen.
Título: Tomografía computarizada de doble energía: nueva tecnología para la reducción de artefactos de metal / Dual-energy computed tomography: new technology for metal artifacts reduction
Fonte: Rev. Asoc. Argent. Ortop. Traumatol;82(1):5-13, mar. 2017. [].
Idioma: es.
Resumo: Introducción: El objetivo fue explorar la utilidad de la tomografía computarizada de doble energía mediante tecnología de imágenes espectrales gemstone y de un programa destinado a la reducción de artefactos de metal (MARS), para evaluar tejidos periprotésicos, y la interpretabilidad diagnóstica de patologías relacionadas con implantes. Materiales y Métodos: Se comparó la densidad ósea, de partes blandas y de grasa en el tejido periprotésico y en tejido de control sin implante, utilizando un escáner de alta definición de tomografía computarizada de doble energía tanto en imágenes policromáticas convencionales, como en monocromáticas virtuales con MARS, en 80 pacientes con prótesis metálicas en diversas regiones musculoesqueléticas. Se valoró la calidad de imagen y la interpretabilidad diagnóstica mediante la escala de Likert. Resultados: Con imágenes policromáticas hubo diferencias significativas entre el área periprotésica en los tres tejidos respecto a los controles (p <0,0001); sin diferencias significativas utilizando imágenes espectrales monocromáticas virtuales-MARS (hueso p = 0,053, partes blandas p = 0,32 y grasa p = 0,13), con más similitud con el tejido normal. Los niveles de ruido fueron significativamente mayores con imágenes policromáticas (p <0,0001) que con imágenes espectrales monocromáticas virtuales-MARS. Se consideraron no interpretables todas las regiones periprotésicas en las imágenes policromáticas y 11 (9%) en las imágenes espectrales monocromáticas virtuales-MARS. No hubo diferencias significativas en la dosis de radiación comparada con la del grupo control (p = 0,21). Conclusiones: La tomografía computarizada de doble energía puede reducir los artefactos periprotésicos, logrando un significativo incremento en la capacidad de identificar tejidos y la interpretabilidad diagnóstica de posibles patologías relacionadas con implantes. Nivel de Evidencia: II

Introduction: To explore the usefulness of dual energy imaging using gemstone spectral imaging technology and a dedicated software for metal artifact reduction (MARS) for the evaluation of periprosthetic tissues, and to assess image interpretability of implant-related complications. Methods: Signal density measurements were performed in periprosthetic and remote (control) areas in bone, soft tissue, and fat among 80 patients using a high definition scanner. Polychromatic images and virtual monochromatic spectral images with MARS were obtained, and image quality and diagnostic interpretability were evaluated using a Likert scale. Results: Using polychromatic images, the periprosthetic area showed significant differences compared to the remote areas among the three tissue explored (p<0.0001 for all); with no significant differences using virtual monochromatic spectral images-MARS (bone p=0.053, soft tissue p=0.32, fat p=0.13), suggesting similar signal density compared to normal (remote) tissue. Furthermore, periprosthetic polychromatic image noise levels were significantly higher than with virtual monochromatic spectral images-MARS (p<0.0001). All periprosthetic areas were deemed non-interpretable using polychromatic images, compared to 11 (9%) using virtual monochromatic spectral images-MARS. There were no differences in radiation dose compared to control group (p=0.21). Conclusions: Virtual monochromatic spectral images-MARS technology has the ability to reduce periprosthetic artifacts, achieving a significant increase to identify tissues and diagnostic interpretability of complications related to the implants. Level of Evidence: II
Descritores: Interpretação de Imagem Radiográfica Assistida por Computador
Intensificação de Imagem Radiográfica
Tomografia Computadorizada por Raios X
Artefatos
Prótese Articular
Metais
-Estudos Prospectivos
Limites: Pessoa de Meia-Idade
Responsável: AR337.1 - Biblioteca A.A.O.T.


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Id: biblio-1008176
Autor: Moura, Patrícia HB de; Lucas, Flávia CA; Tavares-Martins, Ana CC; Germano, Carolina M; Martins, Roberto CC.
Título: Metal content in medicinal teas used in the Urubueua de Fátima river community, Abaetetuba-Pará State, Brazil / Contenido de metal en tés terapéuticos utilizados en la comunidad del Río Urubueua de Fátima, estado de Abaetetuba-Pará, Brasil
Fonte: Bol. latinoam. Caribe plantas med. aromát;18(4):378-391, jul. 2019. tab.
Idioma: en.
Resumo: The content of certain metals in 13 medicinal teas made from 16 plant species was measured by flame photometer and atomic absorption spectrometer with flame methods. The measurements were evaluated against metal intake levels recommended by health authorities. The results indicate that the medicinal teas tested, regularly consumed by inhabitants of the Urubueua de Fátima River Community, Abaetetuba-Para, Brazil, present no risk of poisoning people older than six months. However, decoctions of Mentha sp., Eleutherine bulbosa, Euterpe oleracea, Piper callosum and Hyptis mutabilis, mostly given to children, had Mn values potentially exceeding the recommended maximum intake for infants in the 0-6 months age group, in the quantities customarily administered. Consequently, studies are needed to assess bioavailability for safe human consumption. Results also showed the consumption of medicinal tea alone is not enough to supply an adult's daily metal requirements or treat deficiencies. Additionally, cures emphasized by interviewed Community members might be associated with the bioactivity of organic substances that the medicinal teas contain.

El contenido de algunos metales en 13 tés medicinales de las 16 especies consumidas por los habitantes de la comunidad del Río Urubueua de Fátima, Abaetetuba-Para, Brasil, se evaluó mediante un fotómetro de llama y un espectrómetro de absorción atómica con métodos de llama, y se comparó con los niveles recomendados por las agencias de la salud. Los tés medicinales evaluados no mostraron riesgo de intoxicación para las personas mayores de seis meses de edad, sino las decocciones de Mentha sp., Eleutherine bulbosa, Euterpe oleracea, Piper callosum y Hyptis mutabilis, en su mayoría dirigidos a la ingesta de niños, informaron valores de Mn superiores a la ingesta máxima recomendada para el grupo de infantes (0-6 meses), debido a que estos estudios son necesarios para evaluar la biodisponibilidad para un consumo humano seguro. Los resultados también mostraron que solo el consumo de té medicinal no es suficiente para satisfacer las necesidades diarias recomendadas de ingesta de minerales o para tratar las deficiencias. Además, los informes de curación, enfatizados por los habitantes, indican que la bioactividad observada podría estar asociada a sustancias orgánicas presentes en el té.
Descritores: Plantas Medicinais/química
Extratos Vegetais/química
Chás Medicinais
Metais/análise
-Valores de Referência
Brasil
Responsável: CL1.1 - Biblioteca Central


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Id: biblio-996708
Autor: Consalter, Bruna Gouveia; Miranda, Danielle Mariano de; Souza, Jean Silva de; Ferrarezi, Adriana Dias Martins; Ferrarezi, José Gaspar; Gasques, Luciano Seraphim.
Título: Avaliação da contaminação por cobre e chumbo do lago Aratimbó - Umuarama - Pr / Evaluation of copper and lead contamination of the Aratimbó lake in Umuarama - Paraná
Fonte: Arq. ciências saúde UNIPAR;23(2):107-112, maio-ago. 2019.
Idioma: pt.
Resumo: Este trabalho teve como objetivo quantificar os metais Cobre e Chumbo presentes na água e no sedimento do lago Aratimbó, localizado na cidade de Umuarama-PR e analisar os indicadores abióticos de temperatura e pH da água. As coletas foram feitas em triplicatas, em três pontos distintos, em dois diferentes dias, sendo o primeiro em tempo seco, anterior a chuva e outro logo após a primeira chuva. As amostras tiveram sua temperatura e pH verificado in loco e a determinação dos metais ocorreu por meio de Espectrofotometria de Absorção Atômica por chama. Os resultados de pH obtiveram valores satisfatórios em todos os pontos. Em relação à concentração de metais, na água, houve maior concentração de chumbo antes da chuva e uma concentração abaixo do limite apenas para o cobre no ponto 1. No sedimento, a concentração de ambos metais foi maior antes da chuva, exceto no ponto três, onde a concentração foi maior após a chuva. É possível que os maiores valores de concentração para os metais tenham sido superiores no período de seca em virtude do volume aumentado de água após a chuva, com maior diluição. Assim, podendo atribuir a contaminação às atividades antropogênicas, uma vez que o lago se localiza em região urbana central.

The purpose of this paper was to quantify the copper and lead present in the water and sediments of the Aratimbó lake, located in the city of Umuarama, in the state of Paraná, and to analyze the abiotic indicators of temperature and pH of the water. The samples were taken in triplicate at three different points, on two different days - the first during dry weather, before the rain, and the other after the first rain. The temperature and pH of the samples were verified in locu and the metals were determined through Atomic Absorption Spectrophotometry by flame. The pH results obtained satisfactory values ​​at all points. Regarding the concentration of metals in the water, a higher concentration of lead was observed before the rain and a concentration below the limit was observed only for copper in point 1. In the sediment, the concentration of both metals was higher before the rain, except in point three, where the concentration was also higher after the rain. It is possible that the highest concentration values ​​for the metals were higher in the dry period due to the increased volume of water after rainfall, with higher dilution of the metals, as well as the attribution of contamination to the anthropogenic activities, since the lake is located in a central urban region.
Descritores: Poluição da Água/análise
Cobre/toxicidade
Chumbo/toxicidade
-Chuva
Temperatura
Sedimentos/análise
Rios
Metais/toxicidade
Responsável: BR513.1 - Biblioteca Central


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Id: biblio-838434
Autor: Canpolat, Uğur; Turak, Osman; Özcan, Fırat; Öksüz, Fatih; Mendi, Mehmet Ali; Yayla, Çağrı; Aydoğdu, Sinan.
Título: Impact of free thyroxine levels and other clinical factors on bare metal stent restenosis
Fonte: Arch. endocrinol. metab. (Online);61(2):130-136, Mar.-Apr. 2017. tab, graf.
Idioma: en.
Resumo: ABSTRACT Objective Thyroid hormones have both direct and indirect effects on thermogenesis such as modulating vascular smooth muscle cell proliferation. However, the influence of more subtle changes in thyroid hormones on coronary atherosclerosis remains a matter of speculation. Smooth muscle cells play a crucial role in the pathogenesis of in-stent restenosis (ISR). However, the relationship between free thyroxine (fT4) and ISR has not been studied. In the present study, we aimed to assess the role of preprocedural serum fT4 level on the development of ISR in patients undergoing coronary bare metal stent (BMS) implantation. Materials and methods We enrolled and analyzed clinical, biochemical, and angiographic data from 705 consecutive patients without a history of primary thyroid disease [mean age 60.3 ± 9.3 years, 505 (72%) male]; all patients had undergone BMS implantation and further control coronary angiography owing to stable or unstable angina pectoris. Patients were divided into 3 tertiles based on preprocedural serum fT4 levels. Results ISR was observed in 53 (23%) patients in the lowest tertile, 82 (35%) patients in the second tertile, and 107 (46%) patients in the highest fT4 tertile (p < 0.001). Using multiple logistic regression analysis, five characteristics emerged as independent predictors of ISR: diabetes mellitus, smoking, HDL-cholesterol, stent length, and preprocedural serum fT4 level. In receiver operating characteristics curve analysis, fT4 level > 1.23 mg/dL had 70% sensitivity and 73% specificity (AUC: 0.75, p < 0.001) in predicting ISR. Conclusion Higher preprocedural serum fT4 is a powerful and independent predictor of BMS restenosis in patients with stable and unstable angina pectoris.
Descritores: Stents/efeitos adversos
Reestenose Coronária/etiologia
Reestenose Coronária/sangue
-Valores de Referência
Tiroxina/sangue
Falha de Prótese
Biomarcadores/sangue
Fumar/efeitos adversos
Modelos Logísticos
Reprodutibilidade dos Testes
Estudos Retrospectivos
Fatores de Risco
Seguimentos
Sensibilidade e Especificidade
Angiografia Coronária
Reestenose Coronária/diagnóstico por imagem
Complicações do Diabetes
Angina Instável/etiologia
Angina Instável/sangue
Metais
Limites: Humanos
Masculino
Feminino
Pessoa de Meia-Idade
Idoso
Responsável: BR1.1 - BIREME



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