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Id: biblio-1013979
Autor: Flores Sandí, Grettchen.
Título: Mecanismo carcinogénico asociado a la exposición al Bisfenol A / Carcinogenic mechanism associated of Bisphenol A exposure
Fonte: Rev. costarric. salud pública;28(1):96-104, ene.-jun. 2019.
Idioma: es.
Resumo: Resumen Introducción: El Bisfenol A (BPA) es un producto químico al que los seres humanos están expuestos ampliamente por la vía oral, inhalación y transdérmica. Justificación: Dada la importancia de la patología oncológica que puede estar asociada a exposición a este químico, resulta imprescindible comprender mejor sus posibles mecanismos de acción asociados a carcinogénesis. Objetivo General: Investigar el mecanismo carcinogénico asociado a la exposición a BPA. Resultados: Aunque la mayoría de las investigaciones se han orientado hacia el efecto disruptor endocrino, con la limitante que los estudios in vivo son realizados en animales, existen estudios recientes que muestran su posible efecto carcinogénico en tejidos humanos. Sin embargo, se requiere más investigación sobre el papel del BPA de dosis baja (como ocurre en condiciones ambientales normales) y su efecto en la regulación de los cambios globales de expresión génica y las alteraciones epigenéticas en las células, que permitan establecer vínculos con carcinogénesis; esta revisión demuestra que los estudios realizados hasta la fecha señalan varios factores que pueden estar involucrados, como efectos mutagénicos que incluyen cambios en la transcripción génica y enzimáticos que promueven la proliferación celular limitando la apoptosis y favorecen la angiogénesis y migración de células tumorales. Conclusión: Si bien en la actualidad se reconoce que la célula cancerígena adquiere características patológicas que le ayudan a sobrevivir en el organismo, estas características obedecen a mecanismos moleculares genéticos y epigéneticos, muchos de los cuales han sido descritos para el caso de la exposición humana al BPA.

Abstract Introduction: Bisphenol A (BPA) is a chemical to which humans are extensively exposed orally, inhaled and transdermally. Justification: Given the importance of the oncological pathology that may be associated with exposure to this chemical, it is essential to better understand its possible mechanisms of action associated with carcinogenesis. Objective: To investigate the carcinogenic mechanism associated with BPA exposure. Results: Although the majority of investigations have been oriented towards the endocrine disrupting effect, with the limitation that in vivo studies are carried out in animals, recent studies have shown that they can be carcinogenic in human tissues. However, more research is required on the role of low-dose BPA (as occurs under normal environmental conditions) and its effect on the regulation of global changes in gene expression and epigenetic alterations in cells, which allow establishing links with carcinogenesis; this review shows that the studies carried out to date point to several factors that may be involved, such as mutagenic effects that include changes in gene transcription and enzymes that promote cell proliferation, limiting apoptosis and promoting angiogenesis and migration of tumor cells. Conclusion: Although it is currently recognized that the cancer cell acquires pathological characteristics that help it to survive in the organism, these characteristics are due to genetic and epigenetic molecular mechanisms, many of which have been described for the case of human exposure to BPA.
Descritores: Carcinógenos/análise
Bis-Fenol A-Glicidil Metacrilato/efeitos adversos
Disruptores Endócrinos/análise
-Epigenômica
Carcinogênese
Tipo de Publ: Revisão
Responsável: CR1.1 - BINASSS - Biblioteca Nacional de Salud y Seguridad Social


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Id: biblio-1040230
Autor: Balkaya, Hacer; Arslan, Soley; Pala, Kanşad.
Título: A randomized, prospective clinical study evaluating effectiveness of a bulk-fill composite resin, a conventional composite resin and a reinforced glass ionomer in Class II cavities: one-year results
Fonte: J. appl. oral sci;27:e20180678, 2019. tab, graf.
Idioma: en.
Projeto: Erciyes University Scientific Research Projects Foundation.
Resumo: Abstract Bulk-fill restorative materials such as bulk-fill composite resins and high viscous glass ionomer cements have become very popular materials in operative dentistry because their application is easy and time-saving. Objectives: The aim of this clinical study was to evaluate the clinical performance of a highly viscous reinforced glass ionomer material, a bulk-fill composite resin and a micro hybrid composite resin in Class II restorations. Methodology: In total, 109 Class II restorations were performed in 54 patients using three different restorative materials: Charisma Smart Composite (CSC); Filtek Bulk Fill Posterior Restorative (FBF); Equia Forte Fil (EF). Single Bond Universal adhesive (3M ESPE, Germany) was used with composite resin restorations. The restorations were evaluated using modified USPHS criteria in terms of retention, color match, marginal discoloration, anatomic form, contact point, marginal adaptation, secondary caries, postoperative sensitivity and surface texture. The data were analyzed using Chi-Square, Fischer's and McNemar's tests. Results: At the end of one year, 103 restorations were followed up. No changes were observed during the first 6 months. At the end of one year, there were small changes in composite restorations (FBF and CSC) but no statistically significant difference was observed between the clinical performances of these materials for all criteria (p>0.05). However, there was a statistically significant difference between EF, FBF and CSC groups in all parameters except marginal discoloration, secondary caries and postoperative sensitivity in one-year evaluation (p<0.05). Conclusion: Bulk-fill composite resins and conventional composite resins showed more successful clinical performance than highly viscous reinforced glass ionomers in Class II cavities.
Descritores: Resinas Compostas/uso terapêutico
Restauração Dentária Permanente/métodos
Cimentos de Ionômeros de Vidro/uso terapêutico
-Estudos Prospectivos
Reprodutibilidade dos Testes
Resultado do Tratamento
Bis-Fenol A-Glicidil Metacrilato/uso terapêutico
Distribuição por Sexo
Adaptação Marginal Dentária
Cárie Dentária/terapia
Limites: Humanos
Masculino
Feminino
Adulto
Tipo de Publ: Ensaio Clínico Controlado Aleatório
Responsável: BR28.1 - Serviço de Biblioteca e Documentação Professor Doutor Antônio Gabriel Atta


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Id: lil-780300
Autor: Salas-Castro, Yeni; Lozano-Castro, Felipe.
Título: Estudio in vitro de la microdureza superficial en resinas compuestas de metacrilato y silorano / In vitro study of superficial microhardness in methacrylate and silorane composites
Fonte: Kiru;11(1):69-73, ene.-jun.2014. ilus.
Idioma: es.
Resumo: Evaluar la microdureza superficial in vitro de dos materiales restauradores; una resina de metacrilato Filtek® Z350 XT y una resina de silorano Filtek® P90. Materiales y métodos. Estudio prospectivo, transversal y experimental donde se elaboraron diez cilindros de 6 mm de diámetro por 6 mm de altura de cada uno de los materiales en estudio, siendo polimerizadas por una lámpara LED a 40 segundos, para luego ser almacenadas en agua destilada a 37 ºC durante 24 h. Se realizó la medición de la microdureza de todas las muestras con un microdurómetro aplicando una carga de 500 g por diez segundos para, finalmente, ser observados en un microscopio a 20x. Los datos fueron analizados por la prueba t de Student con un nivel de significancia de 5%. Resultados. El grupo de resina de metacrilato Z350 XT presentó una microdureza superficial media + desviación estándar de 86,40 + 1,29 kg/mm2, mientras que en el grupo de la resina de silorano P90 fue de 84,64 + 1,27 kg/mm2, estas diferencias fueron significativas (p=0,007). Conclusiones. La resina de metacrilato presentó mayor microdureza superficial que la resina de silorano...

To evaluate the in vitro surface microhardness from two restorative materials; Filtek® Z350 XT methacrylate and Filtek® P90 silorane resins. Materials and methods. Prospective, cross-sectional experimental study, ten cylinders were elaborated of 6mm diameter by 6mm high for each one of the materials used in this study, light-cured by LED during 40 seconds to then be stored in distilled water at 37 degrees Celsius for 24 hours. Microhardness measurement was reach at all samples with a microdurometer applying a loading of 500g by 10 second, finally samples were observed in a microscope at 20x magnification. The data were subjectedto the student t-test with a confidence level at 95%. Results. The results showed that group of methacrylate composite Z350 XT had a superficial microhardness average of 86.40 Kg/mm2, while the group of silorane composite P90 showed microhardness average of 84.64 Kg/mm2. The data showed p = 0.007 being statistically significant, between composites observed. Conclusions. Concluding that methacrylate composite presented higher microhardness value instead of silorane composite...
Descritores: Bis-Fenol A-Glicidil Metacrilato
Dureza
EVALUACION
Materiais Dentários
Resinas Compostas
-Epidemiologia Experimental
Estudos Prospectivos
Estudos Transversais
Limites: Humanos
Responsável: PE264.1 - Biblioteca


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Id: biblio-1014403
Autor: MATICK, Anna Carolina Cenci; NAVARRO, Camila Hirata; HIGASHI, Dayla Thyeme; PASCOTTO, Renata Corrêa; FUJIMAKI, Mitsue; TERADA, Raquel Sano Suga.
Título: Avaliação da solubilidade e sorção em água de alguns materiais restauradores diretos / Evaluation of solubility and sorption in water of some direct restorative materials
Fonte: Rev. odontol. UNESP (Online);48:e20180128, 2019. tab.
Idioma: pt.
Resumo: Resumo Introdução A solubilidade e sorção dos materiais restauradores são considerados fatores críticos, pois podem interferir na qualidade e durabilidade das restaurações. Objetivo Avaliar a solubilidade e sorção de água de alguns materiais restauradores. Material e método Foram confeccionados quatorze espécimes de cada um dos seguintes materiais: Equia® Forte, Z100, Fuji IX/ e Vidrion R, os quais foram levados a uma dessecadora e pesados diariamente até estabilização. Em seguida, foram inseridos em recipientes individuais contendo 40 mL de água destilada cada e divididos em dois grupos de acordo com o tempo de armazenagem: 7 ou 30 dias. Ao final de cada período, os espécimes foram retirados da água, pesados, levados à dessecadora e pesados novamente até estabilização. Os resultados foram analisados estatisticamente utilizando os testes ANOVA 2 critérios e Tukey. Resultado Com exceção do Equia® Forte e Z100, os demais materiais, apresentaram uma variação significativa da solubilidade ao longo do tempo. Quanto à sorção, observa-se que apenas o material Z100 não apresentou diferença significativa em relação ao tempo de armazenagem, mas, na comparação entre os materiais, todos apresentaram diferenças significativas em ambos os períodos. Conclusão Após os períodos de armazenagem de 7 e 30 dias em água, os materiais restauradores Equia® Forte e Z100 não apresentam variação significativa da solubilidade, sendo mais estáveis que os materiais Fuji IX e Vidrion R. Os materiais à base de ionômero de vidro, Equia® Forte, Fuji IX e Vidrion R, sofrem mais sorção em água quando comparados ao material Z100 em ambos os períodos.

Abstract Introduction The solubility and sorption parameters of restorative materials are considered critical factors since they may interfere with the quality and durability of restorations. Objective The aim of this study was to evaluate the solubility and water sorption of some restorative materials. Material and method Fourteen specimens were made (10.0 mm x 2.0 mm) of each of the following material: Equia® Forte, Z100, Fuji IX/ e Vidrion R, then taken to a desiccator and weighed daily until stabilized. They were then placed in individual containers with 40mL of distilled water each and divided into two groups according to the storage time: 7 or 30 days. At the end of each period, the specimens were removed from the water, weighed, taken to the desiccator and weighed again until stabilized. The results were analyzed statistically with two-way ANOVA and Tukey. Result Except for Equia® Forte and Z100, the other materials presented a significant variation of solubility over time. As for sorption, it was noticed that only Z100 presented no significant difference in relation to the storage time, but in comparison of the materials, all had significant differences in both 7 and 30 days periods. Conclusion After storage periods of 7 and 30 days in water, the restorative materials Equia® Forte and Z100 do not present significant variation of solubility, being more stable than the materials Fuji IX and Vidrion R. The glass ionomer-based materials, Equia® Forte, Fuji IX and Vidrion R, suffer more sorption in water when compared to Z100 material in both periods.
Descritores: Solubilidade
Água
Restauração Dentária Permanente
Absorção
-Bis-Fenol A-Glicidil Metacrilato
Tratamento Dentário Restaurador sem Trauma
Cimentos de Ionômeros de Vidro
Tipo de Publ: Estudo de Avaliação
Responsável: BR39.2 - Biblioteca Professora Maria Dilma de Oliveira Gonçalves


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Sinhoreti, Mário Alexandre Coelho
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Id: biblio-841154
Autor: OLIVEIRA, Dayane Carvalho Ramos Salles de; SOUZA-JUNIOR, Eduardo José; DOBSON, Adam; CORRER, Ana Rosa Costa; BRANDT, William Cunha; SINHORETI, Mário Alexandre Coelho.
Título: Evaluation of phenyl-propanedione on yellowing and chemical-mechanical properties of experimental dental resin-based materials
Fonte: J. appl. oral sci;24(6):555-560, Nov.-Dec. 2016. tab, graf.
Idioma: en.
Projeto: São Paulo Research Foundation.
Resumo: ABSTRACT Objective To evaluate the influence of phenyl-propanedione on yellowing and chemical-mechanical properties of experimental resin-based materials photoactivated using different light curing units (LCUs). Material and Methods Experimental resin-based materials with the same organic matrix (60:40 wt% BisGMA:TEGDMA) were mechanically blended using a centrifugal mixing device. To this blend, different photoinitiator systems were added in equimolar concentrations with aliphatic amine doubled by wt%: 0.4 wt% CQ; 0.38 wt% PPD; or 0.2 wt% CQ and 0.19 wt% PPD. The degree of conversion (DC), flexural strength (FS), Young’s modulus (YM), Knoop hardness (KNH), crosslinking density (CLD), and yellowing (Y) were evaluated (n=10). All samples were light cured with the following LCUs: a halogen lamp (XL 2500), a monowave LED (Radii), or a polywave LED (Valo) with 16 J/cm2. The results were analysed by two-way ANOVA and Tukey’s test (α=0.05). Results No statistical differences were found between the different photoinitiator systems to KNH, CLS, FS, and YM properties (p≥0.05). PPD/CQ association showed the higher DC values compared with CQ and PPD isolated systems when photoactivated by a polywave LED (p≤0.05). Y values were highest for the CQ compared with the PPD systems (p≤0.05). Conclusion PPD isolated system promoted similar chemical and mechanical properties and less yellowing compared with the CQ isolated system, regardless of the LCU used.
Descritores: Polietilenoglicóis/química
Ácidos Polimetacrílicos/química
Bis-Fenol A-Glicidil Metacrilato/química
Chalconas/química
Cura Luminosa de Adesivos Dentários/métodos
Fotoiniciadores Dentários/química
-Espectrofotometria
Teste de Materiais
Cânfora/análogos & derivados
Cânfora/química
Reprodutibilidade dos Testes
Espectroscopia de Infravermelho com Transformada de Fourier
Pigmentação em Prótese
Cor
Estatísticas não Paramétricas
Maleabilidade
Transição de Fase
Luzes de Cura Dentária
Módulo de Elasticidade
Polimerização
Testes de Dureza
Tipo de Publ: Estudo Comparativo
Estudo de Avaliação
Responsável: BR1.1 - BIREME


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Id: biblio-839519
Autor: FRAGELLI, Camila Maria Bullio; SOUZA, Juliana Feltrin de; BUSSANELI, Diego Girotto; JEREMIAS, Fabiano; SANTOS-PINTO, Lourdes dos; CORDEIRO, Rita de Cássia Loiola.
Título: Survival of sealants in molars affected by molar-incisor hypomineralization: 18-month follow-up
Fonte: Braz. oral res. (Online);31:e30, 2017. tab, graf.
Idioma: en.
Projeto: Fapesp.
Resumo: Abstract The objective of this study was to evaluate the clinical survival of sealants applied in first permanent molars (FPMs) affected by molar-incisor hypomineralization (MIH), at 18 months of follow-up. Forty-one first permanent molars were selected from 21 children, 6–8 years of age. MIH was classified by one calibrated examiner (kappa = 0.80) according to EAPD criteria. The inclusion criteria were fully erupted FPMs with MIH or sound FPMs (without MIH) for which sealant treatment was indicated. The FPMs were assigned to two groups: CG (control group) and HG (MIH group). Both groups were treated with sealant (FluroShield). Clinical follow-up was performed from baseline to 18 months to assess anatomical form, marginal adaptation, retention and presence of caries, according to criteria set by the United States Public Health Service-Modified, and was conducted by a blinded examiner (kappa = 0.80). The actuarial method was used to evaluate the survival of the sealants. The survival rates for the groups were compared using Fisher’s exact test (α = 5%). The cumulative survival rates were 81% at 1 month, 68.8% at 6 months, 68.8% at 12 months, and 62.6% at 18 months for CG, and 88% at 1 month, 84% at 6 months, 76% at 12 months, and 72% at 18 months for HG. No significant difference was found between the groups. The sealants in molars affected by MIH presented a survival rate similar to the sealants in the control, suggesting that sealants may be an adequate approach for preventing carious lesions in MIH-affected molars.
Descritores: Selantes de Fossas e Fissuras/uso terapêutico
Poliuretanos/uso terapêutico
Fluoreto de Sódio/uso terapêutico
Cariostáticos/uso terapêutico
Fluoretos Tópicos/uso terapêutico
Bis-Fenol A-Glicidil Metacrilato/uso terapêutico
Falha de Restauração Dentária
Hipoplasia do Esmalte Dentário/terapia
Restauração Dentária Permanente/métodos
-Fatores de Tempo
Análise de Sobrevida
Estudos Prospectivos
Reprodutibilidade dos Testes
Seguimentos
Resultado do Tratamento
Medição de Risco
Dentição Permanente
Cárie Dentária/prevenção & controle
Esmalte Dentário/efeitos dos fármacos
Limites: Humanos
Masculino
Feminino
Criança
Tipo de Publ: Ensaio Clínico
Responsável: BR1.1 - BIREME


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Id: biblio-889380
Autor: Munir, Bushra; Qadir, Abdul; Tahir, Mohammad.
Título: Negative effects of bisphenol A on testicular functions in albino rats and their abolitions with Tribulus terristeris L
Fonte: Braz. J. Pharm. Sci. (Online);53(3):e00104, 2017. tab, graf.
Idioma: en.
Resumo: ABSTRACT This study was conducted to find out the ameliorative properties of Tribulus terristeris L (TT) on BPA induced spermatotoxicity in male albino rats. Mature male albino rats were divided into five groups, Group A was taken as control for comparison group, whereas the other four groups namely B(vehicle control), C (toxic), D (preventive control) and Group E (amelioration group) received distilled water, olive oil, BPA, TT, and (TT + BPA) respectively. Macroscopic results revealed decreased body weight of rats, weight of testes, and the relative tissue weight index (RTWI) in BPA induced group. Hormonal (testosterone) assay results revealed the decreased values of BPA treated group. Microscopic examination of testis of BPA treated rats showed reduction in leydig cells, decreased diameter of seminiferous tubules and low values of Johnsen's scoring. Histological examination showed discontinuity and irregularity of basement membrane and sloughing of the germinal cell linage. Group E showed the body weights of rats, weight of testes, RTWI, and increased, while reduced level of testosterone, reduced number of Leydig cells, decreased diameter of seminiferous tubules and low values of Johnsen's scoring were restored near to normal. These results demonstrate that TT might be beneficial in combating the spermatotoxicity, induced by BPA.
Descritores: Bis-Fenol A-Glicidil Metacrilato/efeitos adversos
Tribulus/anatomia & histologia
-Hormônios Testiculares/análise
Testosterona/uso terapêutico
Limites: Animais
Masculino
Ratos
Responsável: BR40.1 - DBD - Divisão de Biblioteca e Documentacão do Conjunto das Químicas


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Id: biblio-893652
Autor: Botelho, Maria Paula Jacobucci; Isolan, Cristina Pereira; Schwantz, Júlia Kaster; Lopes, Murilo Baena; Moraes, Rafael Ratto de.
Título: Rubbing time and bonding performance of one-step adhesives to primary enamel and dentin
Fonte: J. appl. oral sci;25(5):523-532, Sept.-Oct. 2017. tab, graf.
Idioma: en.
Resumo: Abstract Objectives: This study investigated whether increasing the concentration of acidic monomers in one-step adhesives would allow reducing their application time without interfering with the bonding ability to primary enamel and dentin. Material and methods: Experimental one-step self-etch adhesives were formulated with 5 wt% (AD5), 20 wt% (AD20), or 35 wt% (AD35) acidic monomer. The adhesives were applied using rubbing motion for 5, 10, or 20 s. Bond strengths to primary enamel and dentin were tested under shear stress. A commercial etch-and-rinse adhesive (Single Bond 2; 3M ESPE) served as reference. Scanning electron microscopy was used to observe the morphology of bonded interfaces. Data were analysed at p<0.05. Results: In enamel, AD35 had higher bond strength when rubbed for at least 10 s, while application for 5 s generated lower bond strength. In dentin, increased acidic monomer improved bonding only for 20 s rubbing time. The etch-and-rinse adhesive yielded higher bond strength to enamel and similar bonding to dentin as compared with the self-etch adhesives. The adhesive layer was thicker and more irregular for the etch-and-rinse material, with no appreciable differences among the self-etch systems. Conclusion: Overall, increasing the acidic monomer concentration only led to an increase in bond strength to enamel when the rubbing time was at least 10 s. In dentin, despite the increase in bond strength with longer rubbing times, the results favoured the experimental adhesives compared to the conventional adhesive. Reduced rubbing time of self-etch adhesives should be avoided in the clinical setup.
Descritores: Bis-Fenol A-Glicidil Metacrilato/química
Colagem Dentária/métodos
Esmalte Dentário/efeitos dos fármacos
Adesivos Dentinários/química
Dentina/efeitos dos fármacos
Metacrilatos/química
-Análise de Variância
Falha de Restauração Dentária
Glicerol/química
Teste de Materiais
Microscopia Eletrônica de Varredura
Reprodutibilidade dos Testes
Resistência ao Cisalhamento
Solventes/química
Propriedades de Superfície/efeitos dos fármacos
Fatores de Tempo
Água/química
Limites: Humanos
Tipo de Publ: Estudo de Avaliação
Responsável: BR1.1 - BIREME


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Id: biblio-893634
Autor: EPASINGHE, Don Jeevanie; YIU, Cynthia Kar Yung; BURROW, Michael Francis.
Título: Mechanical properties, water sorption characteristics, and compound release of grape seed extract-incorporated resins
Fonte: J. appl. oral sci;25(4):412-419, July-Aug. 2017. tab, graf.
Idioma: en.
Resumo: Abstract Objective This study evaluated the effect of grape seed extract (GSE) incorporation on the mechanical properties, water sorption, solubility, and GSE release from the experimental adhesive resins. Material and Methods An experimental comonomer mixture, consisting of 40% Bis-GMA, 30% Bis MP, 28% HEMA, 0.26% camphorquinone and 1% EDMAB, was used to prepare four GSE-incorporated adhesive resins at concentrations of 0.5, 1, 1.5, and 2 wt%. The neat resin without GSE was used as the control. Six resin beams (25 mm x 2 mm x 2 mm) per group were prepared for flexural strength and modulus of elasticity evaluations using a universal testing machine at a crosshead speed of 1 mm/min. Five disks (6 mm in diameter and 2 mm in thickness) per group were used for microhardness measurements using a Leitz micro-hardness tester with Leica Qgo software. Five disks (7 mm in diameter and 2 mm in thickness) per group were prepared and stored in deionized water for 28 days. Water sorption, solubility, and GSE release in deionized water were calculated for each GSE-incorporated adhesive at the end of 28th day. Data was evaluated using one-way ANOVA and Tukey multiple comparisons. Results Flexural strength, modulus of elasticity and microhardness of GSE-incorporated adhesive decreased significantly with incorporation of 1.5% of GSE (p<0.05). Addition of GSE had no effect on the water sorption of the adhesive resins (p=0.33). The solubility of the resin also increased significantly with incorporation of 1.5% of GSE (p<0.05). Quantities of GSE release increased with increased concentration of GSE in the adhesive resin. Conclusion Up to 1% of GSE can be incorporated into a dental adhesive resin without interfering with the mechanical properties or solubility of the resins.
Descritores: Bis-Fenol A-Glicidil Metacrilato/química
Cânfora/análogos & derivados
Extrato de Sementes de Uva/química
Metacrilatos/química
para-Aminobenzoatos/química
Cimentos de Resina/química
-Análise de Variância
Cânfora/química
Módulo de Elasticidade
Testes de Dureza
Teste de Materiais
Maleabilidade
Proantocianidinas/química
Valores de Referência
Reprodutibilidade dos Testes
Solubilidade
Estatísticas não Paramétricas
Fatores de Tempo
Água/química
Tipo de Publ: Estudo de Avaliação
Responsável: BR1.1 - BIREME


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Id: biblio-882158
Autor: Consolmagno-Callejon, Elaine Cristina.
Título: Influência na resistência de união de pinos de fibra de vidro com e sem retenções mecânicas em função dos materiais utilizados para cimentação: teste de 'push-out' / Influence on the bond strength of glass fiber posts with and without mechanical retentions depending of materials used for cementing: push-out test.
Fonte: Bauru; s.n; 2016. 89 p. tab, ilus, graf.
Idioma: pt.
Tese: Apresentada a Universidade de São Paulo. Faculdade de Odontologia de Bauru para obtenção do grau de Doutor.
Resumo: Este estudo teve como objetivo avaliar a influência na resistência de união de pinos de fibra de vidro (PFV) com retenções mecânicas (CRM) e sem retenções (SR), associados a três materiais: RelyX ARC cimento resinoso convencional dual com sistema adesivo Adper Single Bond (ASB), convencional de 2 passos; RelyX U200 cimento resinoso auto condicionante dual e resina flow SDR foto ativada, com sistema adesivo Prime & Bond 2.1 (PB), convencional de 2 passos; nos terços cervical (C), médio (M) e apical (A), por meio do teste de push-out. Sessenta incisivos bovinos foram selecionados, tiveram as coroas seccionadas para padronizar 17mm de raiz e foram submetidas ao tratamento endodôntico, para posterior cimentação do PFV. Foram divididas aleatoriamente em 2 grupos (N=30), quanto ao tipo de PFV: CRM - com retenções mecânicas (Glassix+plus no2) e SR - sem retenções (Exacto no2). Todos os PFV apresentavam formato cônico. Cada grupo foi subdividido em 3 (N=10), quanto ao tipo de material: cimento RelyX ARC+ASB; cimento RelyX U200 (auto condicionante) e resina SDR+PB. Todas as orientações dos fabricantes para tempo de manipulação e foto ativação do material foram rigorosamente respeitadas. As raízes foram mantidas em saliva artificial e decorridas 24h da cimentação dos PFV, foram seccionadas perpendicularmente ao longo eixo, obtendo 9 fatias de aproximadamente 1mm, cuja identificação foi feita de acordo com o terço correspondente. O teste de push-out foi realizado em máquina de ensaio universal com célula de carga de 50N; velocidade de 0,5mm/min, da direção apical para a cervical da fatia até que o pino fosse deslocado, respeitando o formato cônico do canal radicular. Todos os espécimes foram analisados em microscopia óptica, aumento de 200 vezes, quanto aos tipos de falha ocorrido. Os dados foram tabulados considerando as variáveis dos diferentes materiais utilizados para a cimentação, presença ou não de retenções mecânicas nos PFV e terços radiculares. Os valores de resistência de união (Ru) obtidos foram submetidos ao teste de normalidade Kolmogorov- Smirnov, à análise de variância a três critérios (ANOVA) e ao teste LSD de Fisher (p<0,05). Os resultados mostraram diferença estatisticamente significante nos terços C, M e A, respectivamente para os cimentos ARC com pino Glassix+plus, média e desvio padrão (MPa) a seguir, 8,50 (4,76); 6,99 (3,55); 4,71 (2,13) e U200 com pino Exacto: 9,40 (4,93); 8,02 (4,67); 4,67 (1,86); a resina SDR não interagiu significativamente com os PFV CRM 6,78 (2,72); 5,97 (2,45); 2,67 (1,55) e SR 7,24 (3,55); 6,86 (2,84); 4,10 (1,90). A análise microscópica mostrou predominância de falhas adesivas entre cimento e dentina e mista para todos os grupos. O cimento U200 com pino Exacto apresentou o melhor desempenho, seguido do ARC com pino Glassix+plus. A resina SDR teve desempenho semelhante para ambos os PFV. Todos os grupos apresentaram valores de Ru maiores no terço cervical, intermediários no terço médio e menores no terço apical.(AU)

This study aimed to evaluate the influence on the bond strength of glass fiber posts (GFP) with mechanical retention (WMR) and without retentions (NR), associated with three materials: RelyX ARC total-etching resin cement dual cure with Adper Single Bond (ASB) adhesive system, conventional 2 steps; RelyX U200 self-etching resin cement dual cure, and flowable resin SDR, activated by light, with Prime & Bond 2.1 adhesive system conventional 2 steps in the cervical (C), medium (M) and apical (A) thirds by the "push-out" test. Were selected sixty bovine incisors, had the crowns sectioned to root was standardized 17mm, were submitted to endodontic treatment, for cementing the GFP later. Were randomly divided into 2 groups (N=30), according to the GFP: WMR - with mechanical retentions (Glassix+plus ≠2) and NR - without retentions (Exacto ≠2). All GFP had conic shape. Each group was divided into 3 (N=10), according to material: RelyX ARC+ASB, RelyX U200 (self-etching) and flowable resin SDR+PB. All guidelines of manufacturers to handling time and cure time of the material were strictly adhered. The roots were kept in artificial saliva and 24 hours after GFP cementing it were sectioned perpendicular to the long axis, obtaining nine slices of approximately 1mm, which identification was done according to the corresponding third. The "push-out" test was performed with a universal test machine, 50N load cell; crosshead speed of 0.5 mm/min, the load was applied in an apical to cervical direction until the post dislodged from the specimen, respecting the conical shape of the root canal. Subsequently, all specimens were analyzed with optical microscopy 200 times increase to evaluate failure modes. Data were tabulated considering the materials used for cementing, presence or absence of mechanical retentions in GFP and root thirds. The bond strength values (BS) were submitted to Kolmogorov-Smirnov normality test, three-way ANOVA and Fisher's LSD test (p<0.05). The values showed statistically significant differences in thirds C, M and A, respectively for the ARC with Glassix+plus, average and standard deviation (MPa): 8.50 (4.76); 6.99 (3.55); 4.71 (2.13) and U200 with Exact post: 9.40 (4.93); 8.02 (4.67); 4.67 (1.86). SDR resin does not significantly interacted with GFP WMR 6.78 (2.72); 5.97 (2.45); 2.67 (1.55) and NR 7.24 (3.55); 6.86 (2.84); 4.10 (1.90). The microscopic analysis showed predominance of failure between cement and dentine and mixed for all groups. U200 cement with Exacto post had the best performance, followed by ARC with Glassix+plus post, SDR resin has similar performance for both GFP. All groups showed BS values higher in the cervical third, intermediate in the middle third and smaller in the apical third.(AU)
Descritores: Cimentação/métodos
Cimentos Dentários/química
Pinos Dentários
Vidro/química
Técnica para Retentor Intrarradicular
Cimentos de Resina/química
-Análise de Variância
Bis-Fenol A-Glicidil Metacrilato/química
Teste de Materiais
Polietilenoglicóis/química
Ácidos Polimetacrílicos/química
Reprodutibilidade dos Testes
Estatísticas não Paramétricas
Fatores de Tempo
Limites: Animais
Bovinos
Tipo de Publ: Estudo de Avaliação
Responsável: BR28.1 - Serviço de Biblioteca e Documentação Professor Doutor Antônio Gabriel Atta
BR28.1, C765i



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