Base de dados : LILACS
Pesquisa : D02.241.081.193 [Categoria DeCS]
Referências encontradas : 4 [refinar]
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Texto completo SciELO Brasil
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Id: biblio-1132268
Autor: Lino, Renata Calegari; Carvalho, Sabrina Matos de; Noronha, Carolina Montanheiro; Sganzerla, William Gustavo; Rosa, Cleonice Gonçalves da; Nunes, Michael Ramos; Barreto, Pedro Luiz Manique.
Título: Development and Characterization of Poly-ε -caprolactone Nanocapsules Containing β -carotene Using the Nanoprecipitation Method and Optimized by Response Surface Methodology
Fonte: Braz. arch. biol. technol;63:e20190184, 2020. tab, graf.
Idioma: en.
Resumo: Abstract Nanoparticles demonstrate an important role in the protection of bioactive compounds from external factors such as temperature, oxygen and light. In this study, poly-ε-caprolactone (PCL) nanoparticles entrapped β-carotene was produced using the nanoprecipitation method. Firstly, was evaluated the lipophilic surfactant effect and carrier agent of the active compound in the nanocapsules formulation. After choosing the most stable formulation, the nanocapsules production was optimized using β-carotene, caprylic/capric triglycerides (CCT) and soybean lecithin. Response surface methodology (RSM) was adopted to evaluate the influence of soy lecithin concentration, volume of CCT and β-carotene concentration in the particle size, zeta potential, polydispersity index (PDI), encapsulation efficiency and recovery. Formulations containing soy lecithin and CCT demonstrated better stability comparing to the other formulations tested. The nanoparticle formulations presented an optimized particle size below 200 nm, PDI lower than 0.1 and encapsulation efficiency above 95%. Based on the results obtained, the optimum conditions to prepare PCL nanocapsules were 0.2160 mg/mL of β-carotene, 232.42 μL of CCT and 2.59 mg/mL of soy lecithin, suggesting an applicability to promote controlled released of β-carotene in food system.
Descritores: Caproatos
beta Caroteno
Nanotecnologia/métodos
Nanocápsulas
Lactonas
-Precipitação Química
Reatores Biológicos
Otimização de Processos
Responsável: BR1.1 - BIREME


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Id: biblio-893651
Autor: Bizhang, Mozhgan; Domin, Julia; Danesh, Gholamreza; Zimmer, Stefan.
Título: Effectiveness of a new non-hydrogen peroxide bleaching agent after single use - a double-blind placebo-controlled short-term study
Fonte: J. appl. oral sci;25(5):575-584, Sept.-Oct. 2017. tab, graf.
Idioma: en.
Resumo: Abstract Tooth whitening represents perhaps the most common aesthetic procedure in dentistry worldwide. The efficacy of bleaching depends on three aspects: bleaching agent, bleaching method, and tooth color. Objective: This in vivo study aimed to examine whitening effects on frontal teeth of the upper and lower jaws using an over-the-counter (OTC) non-hydrogen peroxide bleaching agent in comparison to a placebo after one single use. Material and methods: Forty subjects (25 female; 15 male) participated in this double-blind randomized placebo-controlled trial. The subjects were randomly allocated to two groups (n=20). The test group received the OTC product (iWhite Instant) and the placebo group received an identically composed product except for the active agents. Each subject was treated with a prefilled tray containing iWhite Instant or the placebo for 20 minutes. The tooth shade of the front teeth (upper and lower jaws) was assessed before (E_0), immediately after (E_1) and 24 h after treatment (E_2), using a shade guide (VITA classical). Statistical testing was accomplished using the Mann-Whitney U test (p<0.001). The dropout rate was 0%. Results: There were no significant differences at E_0 between placebo and test groups regarding the tooth color. Differences in tooth color changes immediately after (ΔE1_0) and 24 h after treatment (ΔE2_0) were calculated for both groups. The mean values (standard deviations) of tooth color changes for ΔE1_0 were 2.26 (0.92) in the test group and 0.01 (0.21) in the placebo group. The color changes for ΔE2_0 showed mean values of 2.15 (1.10) in the test group and 0.07 (0.35) in the placebo group. For ΔE1_0 and ΔE2_0 significant differences were found between the groups. Conclusion: In this short-term study, the results showed that a non-hydrogen peroxide bleaching agent has significant whitening effects immediately and 24 h after a single-use treatment.
Descritores: Compostos de Cálcio/uso terapêutico
Caproatos/uso terapêutico
Gluconatos/uso terapêutico
Lactatos/uso terapêutico
Ftalimidas/uso terapêutico
Clareadores Dentários/uso terapêutico
Clareamento Dental/métodos
-Colorimetria
Sensibilidade da Dentina/induzido quimicamente
Método Duplo-Cego
Medicamentos sem Prescrição/uso terapêutico
Variações Dependentes do Observador
Efeito Placebo
Reprodutibilidade dos Testes
Estatísticas não Paramétricas
Fatores de Tempo
Resultado do Tratamento
Limites: Humanos
Masculino
Feminino
Adolescente
Adulto
Pessoa de Meia-Idade
Adulto Jovem
Tipo de Publ: Ensaio Clínico Controlado
Responsável: BR1.1 - BIREME


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Id: lil-712964
Autor: Chang, H.M.; Wang, Z.H.; Luo, H.N.; Xu, M.; Ren, X.Y.; Zheng, G.X.; Wu, B.J.; Zhang, X.H.; Lu, X.Y.; Chen, F.; Jing, X.H.; Wang, L..
Título: Poly(3-hydroxybutyrate-co-3-hydroxyhexanoate)-based scaffolds for tissue engineering
Fonte: Braz. j. med. biol. res = Rev. bras. pesqui. méd. biol;47(7):533-539, 07/2014. tab.
Idioma: en.
Projeto: the Natural Science Foundation of China; . the Fundamental Research Funds for the Central Universities; . the Funds for the Second Hospital of Xi'an Jiaotong University.
Resumo: Development and selection of an ideal scaffold is of importance for tissue engineering. Poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) (PHBHHx) is a biocompatible bioresorbable copolymer that belongs to the polyhydroxyalkanoate family. Because of its good biocompatibility, PHBHHx has been widely used as a cell scaffold for tissue engineering. This review focuses on the utilization of PHBHHx-based scaffolds in tissue engineering. Advances in the preparation, modification, and application of PHBHHx scaffolds are discussed.
Descritores: /química
ABATTOIRS-HYDROXYBUTYRIC ACID/química
Materiais Biocompatíveis/química
Caproatos/química
Engenharia Tecidual/métodos
Tecidos Suporte/química
-/uso terapêutico
ABATTOIRS-HYDROXYBUTYRIC ACID/uso terapêutico
Materiais Biocompatíveis/uso terapêutico
Osso e Ossos/fisiologia
Caproatos/uso terapêutico
Cartilagem/fisiologia
Liofilização
Músculo Liso/fisiologia
Regeneração
Propriedades de Superfície
Limites: Humanos
Tipo de Publ: Research Support, Non-U.S. Gov't
Revisão
Responsável: BR1.1 - BIREME


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Id: lil-283830
Autor: Pastore, Glaucia Maria; Park, Yong Kun; FMin, David B.
Título: Produçäo de aroma de frutas por espécies de Neurospora isoladas de beiju / Production of fruity aroma by Neurospora species isolated from beiju
Fonte: Rev. microbiol;26(1):55-8, jan.-mar. 1995. ilus, tab.
Idioma: pt.
Resumo: Oito linhagens de Neurospora sp. foram isoladas de beiju, em várias regiöes do Estado do Maranhäo, Brasil. As linhagens apresentaram um agradável aroma de frutas no meio da cultura, enquanto que, as linhagens de Neurospora da coleçäo de cultura NRRL e outras linhagens de Neurospora isoladas de solo na regiäo de Säo Paulo, näo produziram aroma de frutas. Foi detectado por Cromatografia Gasosa por "Headspace" fque o composto responsável pelo aroma de frutas era o etil hexanoato. Além disto, as linhagens de Neurospora sp. isoladas do Maranhäo produziram 3-metil-1-butanol, 1-octen-3-ol, acetato de etila e etanol.
Descritores: Caproatos
Aromatizantes
Neurospora/isolamento & purificação
-Cromatografia
Neurospora/classificação
Responsável: BR734.1 - Biblioteca Central Cesar Lattes - BCCL



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