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Id: lil-785740
Autor: Oguz, Ural; Takci, Zennure; Oguz, Isil Deniz; Resorlu, Berkan; Balta, Ilknur; Unsal, Ali.
Título: Are patients with lichen planus really prone to urolithiasis? Lichen planus and urolithiasis
Fonte: Int. braz. j. urol;42(3):571-577tab.
Idioma: en.
Resumo: ABSTRACT Purpose to investigate whether patients with lichen planus (LP) are really prone to urolithiasis or not. Patients and Methods We performed a prospective analysis of 40 patients diagnosed with lichen planus (LP) (group I), and 40 volunteers did not have LP before (group II). Participants were all checked for urolithiasis by radiological investigations. Blood samples were analyzed for biochemistry parameters including calcium and uric acid. 24-h urine samples were analyzed to investigate oxalate, citrate calcium, uric acid, magnesium, sodium and creatinine. Results Men/women ratio and mean age were similar between group I and II (p>0.05). A presence or history of urolithiasis was detected in 8 (20%) and 2 (%5) patients in group I and II, respectively (p<0.05). Hypocitraturia was the most common anomaly with 35% (n:14) in group I. The rate of hypocitraturia in group II was 12.5% (n:5) and the difference was statistically significantly different (p=0.036). In group I, hyperuricosuria and hyperoxaluria followed with rates of 27.5% (n:11) and 25% (n:10), respectively. The rate of hyperuricosuria and hyperoxaluria were both 5% (n:2) in group II and the differences were significant (p<0.05). Hyperuricemia was another important finding in the patients with LP. It was detected in 13 (32.5%) patients in group I and in 1 (2.5%) participant in group II (p=0.001). Conclusion According to our results, metabolic disorders of urolithiasis were highly detected in the patients with LP. However, similar to the etiology of LP, the exact reasons for these metabolic abnormalities in LP remain a mystery.
Descritores: Urolitíase/etiologia
Líquen Plano/complicações
-Oxalatos/urina
Valores de Referência
Sódio/urina
Ácido Úrico/urina
Ácido Úrico/sangue
Estudos de Casos e Controles
Cálcio/sangue
Estudos Prospectivos
Fatores de Risco
Urinálise
Citrato de Cálcio/urina
Creatinina/urina
Urolitíase/urina
Líquen Plano/urina
Magnésio/urina
Doenças Metabólicas/complicações
Doenças Metabólicas/urina
Pessoa de Meia-Idade
Limites: Humanos
Masculino
Feminino
Adulto
Idoso
Adulto Jovem
Responsável: BR1.1 - BIREME


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Srougi, Miguel
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Id: biblio-954079
Autor: Pucci, Nidia D; Marchini, Giovanni S; Mazzucchi, Eduardo; Reis, Sabrina T; Srougi, Miguel; Evazian, Denise; Nahas, William C.
Título: Effect of phyllanthus niruri on metabolic parameters of patients with kidney stone: a perspective for disease prevention
Fonte: Int. braz. j. urol;44(4):758-764, July-Aug. 2018. tab.
Idioma: en.
Resumo: ABSTRACT Phyllanthus niruri (P.niruri) or stone breaker is a plant commonly used to reduce stone risk, however, clinical studies on this issue are lacking. Objective: To prospectively evaluate the effect of P. niruri on the urinary metabolic parameters of patients with urinary lithiasis. Materials and Methods: We studied 56 patients with kidney stones <10mm. Clinical, metabolic, and ultrasonography assessment was conducted before (baseline) the use of P. niruri infusion for 12-weeks (P. niruri) and after a 12-week (wash out) Statistical analysis included ANOVA for repeated measures and Tukey's/McNemar's test for categorical variables. Significance was set at 5%. Results: Mean age was 44±9.2 and BMI was 27.2±4.4kg/m2. Thirty-six patients (64%) were women. There were no significant changes in all periods for anthropometric and several serum measurements, including total blood count, creatinine, uric acid, sodium, potassium, calcium, urine volume and pH; a significant increase in urinary potassium from 50.5±20.4 to 56.2±21.8 mg/24-hour (p=0.017); magnesium/creatinine ratio 58±22.5 to 69.1±28.6mg/gCr24-hour (p=0.013) and potassium/creatinine ratio 39.3±15.1 to 51.3±34.7mg/gCr24-hour (p=0.008) from baseline to wash out. The kidney stones decreased from 3.2±2 to 2.0±2per patient (p<0.001). In hyperoxaluria patients, urinary oxalate reduced from 59.0±11.7 to 28.8±16.0mg/24-hour (p=0.0002), and in hyperuricosuria there was a decrease in urinary uric acid from 0.77±0.22 to 0.54±0.07mg/24-hour (p=0.0057). Conclusions: P.niruri intake is safe and does not cause significant adverse effects on serum metabolic parameters. It increases urinary excretion of magnesium and potassium caused a significant decrease in urinary oxalate and uric acid in patients with hyperoxaluria and hyperuricosuria. The consumption of P.niruri contributed to the elimination of urinary calculi.
Descritores: Cálculos Renais/metabolismo
Cálculos Renais/prevenção & controle
Phyllanthus/química
Chás de Ervas
-Oxalatos/urina
Potássio/urina
Potássio/sangue
Valores de Referência
Sódio/urina
Sódio/sangue
Ureia/urina
Ureia/sangue
Ácido Úrico/urina
Ácido Úrico/sangue
Cálculos Renais/diagnóstico por imagem
Cálcio/urina
Cálcio/sangue
Estudos Prospectivos
Reprodutibilidade dos Testes
Análise de Variância
Resultado do Tratamento
Creatinina/urina
Creatinina/sangue
Magnésio/urina
Pessoa de Meia-Idade
Limites: Humanos
Masculino
Feminino
Adulto
Adulto Jovem
Responsável: BR1.1 - BIREME


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Id: biblio-1056334
Autor: Afkari, Rouhi; Feizabadi, Mohammad Mehdi; Ansari-Moghadam, Alireza; Safari, Tahereh; Bokaeian, Mohammad.
Título: Simultaneous use of oxalate-degrading bacteria and herbal extract to reduce the urinary oxalate in a rat model: A new strategy
Fonte: Int. braz. j. urol;45(6):1249-1259, Nov.-Dec. 2019. tab, graf.
Idioma: en.
Resumo: ABSTRACT Objective: Urinary stones with oxalate composition can cause kidney failure. Recent findings evidenced that probiotics are effective in reducing oxalate absorption in these subjects based on their high colonic absorption levels at baseline. The purpose of this study was to evaluate the effect of the simultaneous use of oxalate-degrading bacteria, Urtica dioica and T. terrestris extract in reducing urinary oxalate. Materials and Methods: Anti-urolithiatic activity of Urtica dioica and T. terrestris extract and probiotic by using ethylene glycol induced rat model. In this study, 4 strains of Lactobacillus and 2 strains of Bifidobacterium and also 2 strains of L. paracasei (that showed high power in oxalate degrading in culture media) were used. Male Wistar rats were divided into four groups (n=6). The rats of group-I received normal diet (positive control group) and groups-II (negative control group), III, IV rats received diet containing ethylene glycol (3%) for 30 days. Groups III rats received Urtica dioica and T. terrestris extract. Groups IV rats received extracts + probiotic for 30 days. Findings: The results show that the use of herbal extracts (Urtica dioica and T. terrestris) reduced the level of urinary oxalate and other parameters of urine and serum. Also, the accumulation of calcium oxalate crystals in the kidney tissue was significantly reduced. Conclusion: Considering that the formation of calcium oxalate crystals can cause inflammation and tissue damage in the kidney, the use of herbal extracts with oxalate degrading bacteria can be a new therapeutic approach to preventing the formation of kidney stones.
Descritores: Oxalatos/urina
Hiperoxalúria/prevenção & controle
Extratos Vegetais/farmacologia
Probióticos/farmacologia
Urtica dioica/química
Tribulus/química
-Valores de Referência
Fatores de Tempo
Nitrogênio da Ureia Sanguínea
Cálculos Renais/urina
Cálculos Renais/prevenção & controle
Cálcio/análise
Reprodutibilidade dos Testes
Ratos Wistar
Creatinina/análise
Túbulos Renais/química
Limites: Animais
Masculino
Tipo de Publ: Estudo de Avaliação
Responsável: BR1.1 - BIREME


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Id: biblio-1165163
Autor: Negri Armando L; Spivacow Francisco R; Del Valle Elisa E.
Título: La dieta en el tratamiento de la litiasis renal. Bases fisiopatológicas / [Diet in the treatment of renal lithiasis. Pathophysiological basis].
Fonte: Medicina (B.Aires);73(3):267-71, jun. 2013.
Idioma: es.
Resumo: The composition of urine is influenced by diet and changes in dietary factors have been proposed to modify the risk of recurrent nephrolithiasis. Nutrients that have been implicated include calcium, oxalate, sodium, animal protein, magnesium and potassium. There is significant evidence showing that a high calcium diet is associated with a reduction of lithogenic risk. One of the possible mechanisms to explain this apparent paradox is that the higher intake of calcium in the intestine binds with dietary oxalate, reducing its absorption and urinary excretion. Oxalate from the diet seems to provide only a small contribution to excretion and dietary restriction is appropriate only in those with hyperoxaluria and hyperabsorption. Observational studies have shown a positive and independent association between sodium intake and the formation of new kidney stones. Consumption of animal protein creates an acid load that increases urinary excretion of calcium and uric acid and reduced citrate, all factors that could participate in the genesis of stones. Potassium-rich foods increase urinary citrate because of its alkali content. In prospective observational studies, diets rich in magnesium were associated with a lower risk of kidney stone formation in men. In conclusion, diet is a key element in the management of the patient with kidney stones but always subordinated to present metabolic risk factors.
Descritores: Nefrolitíase/dietoterapia
-Cálcio na Dieta/administração & dosagem
Hiperoxalúria/etiologia
Humanos
Nefrolitíase/fisiopatologia
Oxalatos/administração & dosagem
Proteínas na Dieta/administração & dosagem
Sódio na Dieta/administração & dosagem
Tipo de Publ: Resumo em Inglês
Artigo de Revista
Responsável: AR5.1 - Centro de Gestión del Conocimiento y las Comunicaciónes


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Id: biblio-1040236
Autor: Selistre, Luciano da Silva; Cochat, Pierre; Rech, Dener lizot; Parant, François; Souza, Vandréa Carla de; Dubourg, Laurence.
Título: Association between glomerular filtration rate (measured by high-performance liquid chromatography with iohexol) and plasma oxalate / Associação entre taxa de filtração glomerular (medida por cromatografia liquida de alto desempenho com iohexol) e oxalato plasmático
Fonte: J. bras. nefrol;40(1):73-76, Jan.-Mar. 2018. tab, graf.
Idioma: en.
Resumo: ABSTRACT Introduction: Secondary hyperoxalemia is a multifactorial disease that affects several organs and tissues in patients with native or transplanted kidneys. Plasma oxalate may increase during renal failure because it is cleared from the body by the kidneys. However, there is scarce evidence about the association between glomerular filtration rate and plasma oxalate, especially in the early stages of chronic kidney disease (CKD). Methods: A case series focuses on the description of variations in clinical presentation. A pilot study was conducted using a cross-sectional analysis with 72 subjects. The glomerular filtration rate (GFR) and plasma oxalate levels were measured for all patients. Results: Median (IQR) GFR was 70.50 [39.0; 91.0] mL/min/1.73 m2. Plasma oxalate was < 5.0 µmol/L in all patients with a GFR > 30 mL/min/1.73m2. Among the 14 patients with severe CKD (GFR < 30 mL/min/1.73 m2) only 4 patients showed a slightly increased plasma oxalate level (between 6 and 12 µmol/L). Conclusion: In non-primary hyperoxaluria, plasma oxalate concentration increases when GFR < 30mL/min/1.73 m2 and, in our opinion, values greater than 5 µmol/L with a GFR > 30 mL/min/1.73 m2 are suggestive of primary hyperoxaluria. Further studies are necessary to confirm plasma oxalate increase in patients with low GFR levels (< 30mL/min/1.73 m2).

RESUMO Introdução: A hiperoxalemia secundária é uma doença multifatorial que afeta vários órgãos e tecidos em pacientes com rins nativos ou transplantados. O oxalato plasmático pode aumentar durante a insuficiência renal porque é eliminado do corpo pelos rins. No entanto, há evidências escassas sobre a associação entre taxa de filtração glomerular e oxalato plasmático, especialmente nos estágios iniciais da doença renal crônica (DRC). Métodos: uma casuística centrada na descrição das variações na apresentação clínica. Foi realizado um estudo piloto a partir da análise transversal com 72 indivíduos. As taxas de filtração glomerular (TFG) e os níveis plasmáticos de oxalato foram medidos para todos os pacientes. Resultados: A TFG mediana (IIQ) foi de 70,50 [39,0; 91,0] mL/min/1,73 m2. O nível plasmático de oxalato foi < 5,0 µmol/L em todos os pacientes com TFG > 30 mL/min/1,73 m2. Entre os 14 pacientes com DRC grave (TFG < 30 mL/min/1,73 m2), apenas quatro apresentaram ligeiro aumento do nível plasmático de oxalato (entre 6 e 12 µmol/L). Conclusão: Na hiperoxalúria não primária, a concentração plasmática de oxalato aumenta quando TFG < 30 mL/min/1,73 m2 e, em nossa opinião, valores superiores a 5 µmol/L com TFG > 30 mL/min/1,73 m2 sugerem presença de hiperoxalúria primária. Estudos adicionais são necessários para confirmar o aumento do oxalato plasmático em pacientes com níveis baixos de TFG (< 30 mL/min/1,73 m2).
Descritores: Oxalatos/sangue
Iohexol/metabolismo
Cromatografia Líquida de Alta Pressão
Insuficiência Renal Crônica/fisiopatologia
Insuficiência Renal Crônica/sangue
Taxa de Filtração Glomerular
-Projetos Piloto
Limites: Humanos
Masculino
Feminino
Adulto
Pessoa de Meia-Idade
Responsável: BR1.1 - BIREME


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Id: lil-755884
Autor: Sujatha, D; Singh, Kiranpal; Vohra, Mursalin; Kumar, K. Vijay; Sunitha, S.
Título: Antilithiatic Activity of phlorotannin rich extract of Sarghassum Wightii on Calcium Oxalate Urolithiais ­ In Vitro and In VivoEvaluation
Fonte: Int. braz. j. urol;41(3):511-520, May-June 2015. tab, ilus.
Idioma: en.
Resumo: ABSTRACTPurpose:

Urolithiasis is a common urological disorder responsible for serious human affliction and cost to the society with a high recurrence rate. The aim of the present study was to systematically evaluate the phlorotannin rich extract of Sargassum wightii using suitable in vitro and in vivo models to provide scientific evidence for its antilithiatic activity.

Materials and Methods:

To explore the effect of Sargassum wightii on calcium oxalate crystallization, in vitro assays like crystal nucleation, aggregation and crystal growth were performed. Calcium oxalate urolithiasis was induced in male Sprague dawley rats using a combination of gentamicin and calculi producing diet (5% ammonium oxalate and rat pellet feed). The biochemical parameters like calcium, oxalate, magnesium, phosphate, sodium and potassium were evaluated in urine, serum and kidney homogenates. Histopathological studies were also done to confirm the biochemical findings.

Results:

The yield of Sargassum wightii extract was found to be 74.5 gm/kg and confirmed by quantitative analysis. In vitro experiments with Sargassum wightii showed concentration dependent inhibition of calcium oxalate nucleation, aggregation and growth supported by SEM analysis. In the in vivo model, Sargassum wightiireduced both calcium and oxalate supersaturation in urine, serum and deposition in the kidney. The biochemical results were supported by histopathological studies.

Conclusion:

The findings of the present study suggest that Sargassum wightii has the ability to prevent nucleation, aggregation and growth of calcium oxalate crystals. Sargassum wightii has better preventive effect on calcium oxalate stone formation indicating its strong ...

Descritores: Oxalato de Cálcio/antagonistas & inibidores
Extratos Vegetais/farmacologia
Sargassum/química
Taninos/farmacologia
Urolitíase/prevenção & controle
-Oxalato de Cálcio/química
Cálcio/análise
Cristalização
Rim/efeitos dos fármacos
Magnésio/análise
Modelos Animais
Oxalatos/análise
Fósforo/análise
Distribuição Aleatória
Ratos Sprague-Dawley
Valores de Referência
Reprodutibilidade dos Testes
Fatores de Tempo
Resultado do Tratamento
Limites: Animais
Masculino
Tipo de Publ: Estudo de Avaliação
Responsável: BR1.1 - BIREME


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Id: biblio-963358
Autor: Castillo Arteaga, Roger David; Burbano-Rosero, Edith Mariela; Otero-Ramírez, Iván Darío; Roncallo, Juan Camilo; Hidalgo-Bonilla, Sandra Patricia; Fernández-Izquierdo, Pablo; Salcedo-Reyes, Juan Carlos.
Título: Polyhydroxyalkanoate biosynthesis by oxalotrophic bacteria from high Andean soil / Biosíntesis de polihidrxialcanoato por bacterias oxalotróficas de suelos altoandinos / Biossínteses de polihidroxialcanoato por bactérias oxalotróficas de solos andinos
Fonte: Univ. sci;23(1):35-59, Jan.-Apr. 2018. tab, graf.
Idioma: en.
Resumo: Abstract Oxalate is a highly oxidized organic acid anion used as a carbon and energy source by oxalotrophic bacteria. Oxalogenic plants convert atmospheric CO2 into oxalic acid and oxalic salts. Oxalate-salt formation acts as a carbon sink in terrestrial ecosystems via the oxalate-carbonate pathway (OCP). Oxalotrophic bacteria might be implicated in other carbon-storage processes, including the synthesis of polyhydroxyalkanoates (PHAs). More recently, a variety of bacteria from the Andean region of Colombia in Narino have been reported for their PHA-producing abilities. These species can degrade oxalate and participate in the oxalate-carbonate pathway. The aim of this study was to isolate and characterize oxalotrophic bacteria with the capacity to accumulate PHA biopolymers. Plants of the genus Oxalis were collected and bacteria were isolated from the soil adhering to the roots. The isolated bacterial strains were characterized using biochemical and molecular biological methods. The consumption of oxalate in culture was quantified, and PHA production was monitored in batch fermentation. The polymeric composition was characterized using gas chromatography. Finally, a biosynthetic pathway based on our findings and on those from published sources is proposed. Strains of Bacillus spp. and Serratia sp. were found to metabolize calcium oxalate and synthesize PHA.

Resumen El oxalato es un anión de ácido orgánico altamente oxidado usado como fuente carbono y energía por bacterias oxalotróficas. Las plantas oxalogénicas convierten CO2 atmosférico en ácido oxálico y sales oxálicas. La formación de sales de oxalato actúa como un sumidero de carbono en ecosistemas terrestres via oxalato-carbonato (OCP). Las bacterias oxalotróficas podrían estar implicadas en otros procesos de almacenamiento de carbono, incluyendo la síntesis de polihidroxialcanoatos (PHAs). Recientemente, una variedad de bacterias de la región andina colombiana en Nariño ha sido reportada por su habilidad para producir PHAs. Estas especies pueden degradar oxalato y participar en la vía del oxalato-carbonato. El objetivo de este estudio fue aislar y caracterizar bacterias oxalotróficas con capacidad de acumular biopolímeros PHA. Se colectaron plantas del genero Oxalis y se aislaron bacterias del suelo adheridas a las raíces. Las cepas bacterianas aisladas se caracterizaron usando métodos bioquímicos y de biología molecular. Se cuantificó el consumo de oxalato en cultivo, y se monitoreó la producción de PHA en fermentación por lotes. La composición polimérica se caracterizó usando cromatografía de gases. Finalmente, se propone una via biosintética basada en nuestros hallazgos y en los de otras fuentes publicadas. Se encontró que las cepas de Bacillus spp. y Serratia sp. metabolizan oxalato de calcio y sintetizan PHA.

Resumo O oxalato é um ânion de ácido orgânico altamente oxidado utilizado como fonte de carbono e nergía por bactérias oxalotróficas. As plantas oxalogênicas convertem CO2 atmosférico em ácido oxálico e sais oxálicos. A formação de sais de oxalato atua como um sumidouro de carbono em ecossistemas terrestres via oxalato-carbono (OCP). As bactérias oxalotróficas poderiam estar envolvidas em outros processos de armazenamento de carbono, incluindo a sínteses de polihidroxialcanoatos (PHAs). Recentemente, uma variedade de bactérias da região Andina colombiana no Departamento de Nariño foi reportada devido a sua habilidade para produzir PHAs. Estas espécies podem degradar oxalato e participar na via oxalato-carbono. O objetivo de esse estudo foi isolar e caracterizar bactérias oxalotróficas com capacidade de acumular biopolímeros PHA. Plantas do género Oxalis foram coletadas e se isolaram bactérias do solo aderido a suas raízes. As cepas bacterianas isoladas se caracterizaram utilizando métodos bioquímicos e de biologia molecular. O consumo de oxalato em cultivo foi quantificado, e a produção de PHA foi monitorada em fermentação por lotes. A composição polimérica se caracterizou utilizando Cromatografia de Gases. Finalmente, se propõe uma via biossintética baseada em nossos resultados juntamente com resultados da literatura. Se encontrou que as cepas de Bacillus spp. e Serratia sp. metabolizam oxalato de cálcio e sintetizam PHA.
Descritores: Oxalatos
Bactérias/classificação
Cromatografia Gasosa
Responsável: CO185.1 - Biblioteca Alfonso Borrero Cabal, S. J.


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Id: biblio-885212
Autor: Zmener, Osvaldo; Della Porta, Roberto; Pameijer, Cornelis H.
Título: Endodoncia y operatoria dental 4. Hipersensibilidad dentinaria: ensayo preliminar ex vivo de un modelo experimental para su tratamiento / Endodontics and operative dentistry 4. Dentine hypersensitivity: an ex vivo preliminary assay of an experimental model
Fonte: Rev. Asoc. Odontol. Argent;106(1):5-11, mar. 2018. ilus, tab, graf.
Idioma: es.
Resumo: Objetivo: Determinar el grado de confiabilidad de un modelo de dentina humana para evaluar la calidad de oclusión de los túbulos dentinarios luego del uso de dos agentes desestabilizantes que contienen oxalato de potasio. Materiales y métodos: Se obtuvieron dos secciones horizontales en forma de discos de dentina de 0,8 mm de espesor de cada uno de 21 terceros molares sanos extraídos por razones periodontales, ortodóncicas o quirúrgicas. El barro dentinario de las superficies coronaria y pulpar de los discos se eliminó con ácido fosfórico al 35% y posterior lavado con suero fisiológico y secado. De cada molar se separó un disco para el grupo 1 (n=20). Los segundos discos de cada molar se destinaron al grupo 2 (n=20). Y los dos discos del molar restante no recibieron tratamiento (controles negativos). El ensayo se realizó en dos etapas. En la primera, las superficies coronarias de los discos del grupo 1 se trataron con Klepp Desensitizer, mientras que en el grupo 2 se empleó BisBlock Desensitizer. Posteriormente, se metalizaron con oro-paladio y se observaron en un microscopio electrónico de barrido. En la segunda etapa, los discos se retiraron del microscopio, se invirtieron de posición, y la superficie pulpal ubicada en posición superior se lavó con suero, se secó, se metalizó y se observó nuevamente con el microscopio. Con el objeto de realizar el análisis químico de los agentes desestabilizantes, se obtuvieron otros dos discos a partir de un molar adicional y se prepararon ambos siguiendo el mismo protocolo que en los discos experimentales. Uno de ellos se trató con Klepp Desensitizer, y el otro, con BisBlock Desensitizer. Finalmente, las superficies pulpares de ambos discos adicionales se metalizaron con carbón y se examinaron mediante un análisis de energía dispersiva de rayos X. Resultados: En la primera etapa del ensayo, la superficie coronaria de los 20 discos de cada grupo se encontraba cubierta por una capa uniforme de cristales precipitados a partir de ambos agentes desestabilizantes. En la segunda etapa, la superficie pulpar de los 20 discos del grupo 1 reveló que todos los túbulos dentinarios estaban totalmente ocluidos por los cristales en nueve (n=9) casos. Lo mismo ocurrió en ocho (n=8) discos del grupo 2. En ambos casos los cristales ocluyeron totalmente los túbulos hasta una profundidad de 0,8 mm. En 11 (n=11) y 12 (n=12) discos de los grupos 1 y 2 respectivamente se observaron túbulos parcialmente ocluidos o bien una combinación de estos con túbulos vacíos. Las diferencias entre grupos no fueron significativas (P>0,05). En los controles negativos todos los túbulos se encontraban vacíos. El análisis de energía dispersiva de rayos X reveló que los cristales precipitados a partir de ambos agentes desestabilizantes dentro de los túbulos contenían importantes concentraciones de calcio y trazas de potasio. Conclusiones: El modelo ensayado parecería ser adecuado para comparar ex vivo la calidad de protección de la superficie dentinaria producida por los agentes desestabilizantes a base de oxalato de potasio (AU)
Descritores: Sensibilidade da Dentina
Oxalatos
Compostos de Potássio
-Polpa Dentária
Permeabilidade da Dentina
Microscopia Eletrônica de Varredura
Análise Estatística
Limites: Humanos
Tipo de Publ: Estudo de Avaliação
Responsável: AR29.1 - Biblioteca


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Id: biblio-864093
Autor: Canova, Giovana Calicchio(aut).
Título: Estudo in vitro do efeito de agentes anti-hiperestésicos na permeabilidade dentinária por meio de testes de condutividade hidráulica e de espectroscopia de impedância eletroquímica / In vitro study of the effect of anti-hiperesthesic agents in dentin permeability through hydraulic conductance and eletrochemical impedance spectroscopy.
Fonte: Bauru; s.n; 2007. 132 p.
Idioma: pt.
Tese: Apresentada a Universidade de São Paulo. Faculdade de Odontologia de Bauru para obtenção do grau de Doutor.
Descritores: Permeabilidade da Dentina
Sensibilidade da Dentina
Impedância Elétrica
-Polpa Dentária
Fosfatos de Cálcio/uso terapêutico
Oxalatos/uso terapêutico
Responsável: BR28.1 - Serviço de Biblioteca e Documentação Professor Doutor Antônio Gabriel Atta
BR28.1, C165e


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Texto completo SciELO Brasil
Amaro, Joäo Luiz
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Id: lil-723958
Autor: Turney, Benjamin; Robertson, William; Wiseman, Oliver; Amaro, Carmen Regina P. R.; Leitão, Victor A.; Silva, Isabela Leme da; Amaro, João Luiz.
Título: Use of the probability of stone formation (PSF) score to assess stone forming risk and treatment response in a cohort of Brazilian stone formers
Fonte: Int. braz. j. urol;40(4):507-512, Jul-Aug/2014. tab, graf.
Idioma: en.
Resumo: Introduction The aim was to confirm that PSF (probability of stone formation) changed appropriately following medical therapy on recurrent stone formers. Materials and Methods Data were collected on 26 Brazilian stone-formers. A baseline 24-hour urine collection was performed prior to treatment. Details of the medical treatment initiated for stone-disease were recorded. A PSF calculation was performed on the 24 hour urine sample using the 7 urinary parameters required: voided volume, oxalate, calcium, urate, pH, citrate and magnesium. A repeat 24-hour urine sample was performed for PSF calculation after treatment. Comparison was made between the PSF scores before and during treatment. Results At baseline, 20 of the 26 patients (77%) had a high PSF score (> 0.5). Of the 26 patients, 17 (65%) showed an overall reduction in their PSF profiles with a medical treatment regimen. Eleven patients (42%) changed from a high risk (PSF > 0.5) to a low risk (PSF < 0.5) and 6 patients reduced their risk score but did not change risk category. Six (23%) patients remained in a high risk category (> 0.5) during both assessments. Conclusions The PSF score reduced following medical treatment in the majority of patients in this cohort. .
Descritores: Medição de Risco/métodos
Urolitíase/terapia
Urolitíase/urina
-Estudos de Coortes
Fosfatos de Cálcio/urina
Citratos/urina
Magnésio/urina
Oxalatos/urina
Probabilidade
Valores de Referência
Reprodutibilidade dos Testes
Fatores de Risco
Fatores de Tempo
Resultado do Tratamento
Ácido Úrico/urina
Urolitíase/etiologia
Urolitíase/patologia
Limites: Adulto
Idoso
Feminino
Humanos
Masculino
Pessoa de Meia-Idade
Responsável: BR1.1 - BIREME



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