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Id: biblio-1253015
Autor: Usta-Gorgun, Buse; Yilmaz-Ersan, Lutfiye.
Título: Short-chain fatty acids production by Bifidobacterium species in the presence of salep
Fonte: Electron. j. biotechnol;47:29-35, sept. 2020. tab, graf.
Idioma: en.
Projeto: Commission of Scientific Research Projects of Bursa Uludag University, Bursa, Turkey.
Resumo: BACKGROUND: Salep is obtained by grinding dried orchid tubers and used as a valuable ingredient in the food industry. Because of the glucomannan content of salep, it is thought to have prebiotic potential. However, there is little information in studies concerning the fermentation characteristics and potential prebiotic properties of salep. The objective of this study was to investigate the effect of salep on bifidobacterial growth by measuring the highest optical density (OD), calculating the specific growth rates, and determining the production of lactic acid and short-chain fatty acids (acetic, propionic, and butyric acid) as a result of bacterial fermentation. RESULT: The OD and pH values obtained in this study showed that salep was utilized as a source of assimilable carbon and energy by the Bifidobacterium species (BS). All Bifidobacterium strains produced lactic, acetic, propionic, and butyric acid, indicating that salep is readily fermented by these bacteria. Salep at 1% (w/v) showed a similar effect on bifidobacterial growth as that promoted by 1% (w/v) glucose used as a traditional carbon source. CONCLUSIONS: Bifidobacterium species can develop in media containing salep as well as in glucose and exhibit the potential to be used as new sources of prebiotics.
Descritores: Pós/metabolismo
Bifidobacterium/crescimento & desenvolvimento
Bifidobacterium/metabolismo
Ácidos Graxos Voláteis/biossíntese
-Propionatos/análise
Propionatos/metabolismo
Indústria Alimentícia
Ácido Acético/análise
Ácido Acético/metabolismo
Ácido Láctico/análise
Ácido Láctico/metabolismo
Probióticos
Ácido Butírico/análise
Ácido Butírico/metabolismo
Ácidos Graxos Voláteis/análise
Prebióticos
Fermentação
Concentração de Íons de Hidrogênio
Responsável: CL1.1 - Biblioteca Central


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Id: biblio-1223238
Autor: Li, Xianjun; Wang, Junhuan; Wu, Wei; Jia, Yang; Fan, Shuanghu; Su Hlaing, Thet; Khokhar, Ibatsam; Yan, Yanchun.
Título: Cometabolic biodegradation of quizalofop-p-ethyl by Methylobacterium populi YC-XJ1 and identification of QPEH1 esterase
Fonte: Electron. j. biotechnol;46:38-49, jul. 2020. ilus, graf.
Idioma: en.
Projeto: National Natural Science Foundation of China; . Basic Research Fund of Chinese Academy of Agricultural Sciences.
Resumo: BACKGROUND: Quizalofop-p-ethyl (QPE), a unitary R configuration aromatic oxyphenoxypropionic acid ester (AOPP) herbicide, was widely used and had led to detrimental environmental effects. For finding the QPEdegrading bacteria and promoting the biodegradation of QPE, a series of studies were carried out. RESULTS: A QPE-degrading bacterial strain YC-XJ1 was isolated from desert soil and identified as Methylobacterium populi, which could degrade QPE with methanol by cometabolism. Ninety-seven percent of QPE (50 mg/L) could be degraded within 72 h under optimum biodegradation condition of 35°C and pH 8.0. The maximum degradation rate of QPE was 1.4 mg/L/h, and the strain YC-XJ1 exhibited some certain salinity tolerance. Two novel metabolites, 2-hydroxy-6-chloroquinoxaline and quinoxaline, were found by high-performance liquid chromatography/mass spectroscopy analysis. The metabolic pathway of QPE was predicted. The catalytic efficiency of strain YC-XJ1 toward different AOPPs herbicides in descending order was as follows: haloxyfop-pmethyl ≈ diclofop-methyl ≈ fluazifop-p-butyl N clodinafop-propargyl N cyhalofop-butyl N quizalofop-p-ethyl N fenoxaprop-p-ethyl N propaquizafop N quizalofop-p-tefuryl. The genome of strain YC-XJ1 was sequenced using a combination of PacBio RS II and Illumina platforms. According to the annotation result, one α/ß hydrolase gene was selected and named qpeh1, for which QPE-degrading function has obtained validation. Based on the phylogenetic analysis and multiple sequence alignment with other QPE-degrading esterases reported previously, the QPEH1 was clustered with esterase family V. CONCLUSION: M. populi YC-XJ1 could degrade QPE with a novel pathway, and the qpeh1 gene was identified as one of QPE-degrading esterase gene.
Descritores: Propionatos/metabolismo
Quinoxalinas/metabolismo
Methylobacterium/metabolismo
-Microbiologia do Solo
Biodegradação Ambiental
Methylobacterium/enzimologia
Methylobacterium/genética
Análise de Sequência de Proteína
Esterases/análise
Esterases/metabolismo
Herbicidas
Hidrolases/análise
Hidrolases/metabolismo
Hidrólise
Responsável: CL1.1 - Biblioteca Central


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Texto completo SciELO Chile
Texto completo
Id: biblio-950715
Autor: Sytar, Oksana; Borankulova, Asel; Hemmerich, Irene; Rauh, Cornelia; Smetanska, Iryna.
Título: Effect of chlorocholine chlorid on phenolic acids accumulation and polyphenols formation of buckwheat plants
Fonte: Biol. Res;47:1-7, 2014. graf, tab.
Idioma: en.
Resumo: BACKGROUND: Effect of chlorocholine chloride (CCC) on phenolic acids composition and polyphenols accumulation in various anatomical parts (stems, leaves and inflorescences) of common buckwheat (Fagopyrum esculentum Moench) in the early stages of vegetation period were surveyed. RESULTS: Treatment of buckwheat seeds with 2% of CCC has been increased content of total phenolics in the stems, leaves and inflorescences. On analyzing the different parts of buckwheat plants, 9 different phenolic acids - vanilic acid, ferulic acid, trans-ferulic acid, chlorogenic acid, salycilic acid, cinamic acid, p-coumaric acid, p-anisic acid, methoxycinamic acid and catechins were identified. The levels of identified phenolic acids varied not only significantly among the plant organs but also between early stages of vegetation period. Same changes as in contents of chlorogenic acid, ferulic acid, trans-ferulic acid were found for content of salycilic acid. The content of these phenolic acids has been significant increased under effect of 2% CCC treatment at the phase I (formation of buds) in the stems and at the phase II (beginning of flowering) in the leaves and then inflorescences respectively. The content of catechins as potential buckwheat antioxidants has been increased at the early stages of vegetation period after treatment with 2% CCC. CONCLUSIONS: The obtained results suggest that influence of CCC on the phenolics composition can be a result of various mechanisms of CCC uptake, transforming and/or its translocation in the buckwheat seedlings.
Descritores: Clormequat/farmacologia
Fagopyrum/efeitos dos fármacos
Polifenóis/biossíntese
Hidroxibenzoatos/metabolismo
-Propionatos
Sementes/efeitos dos fármacos
Sementes/metabolismo
Catequina/análise
Ácido Clorogênico/análise
Cromatografia Líquida de Alta Pressão
Compostos de Tungstênio
Caules de Planta/efeitos dos fármacos
Caules de Planta/metabolismo
Folhas de Planta/efeitos dos fármacos
Folhas de Planta/metabolismo
Fagopyrum/crescimento & desenvolvimento
Fagopyrum/metabolismo
Ácidos Cumáricos/análise
Inflorescência/efeitos dos fármacos
Inflorescência/metabolismo
Éteres de Hidroxibenzoatos/análise
Hidroxibenzoatos/química
Molibdênio
Antioxidantes/análise
Antioxidantes/metabolismo
Tipo de Publ: Research Support, Non-U.S. Gov't
Responsável: CL1.1 - Biblioteca Central


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Campos, Gisélia
Baptista, Kleber Eduardo Silva
Id: lil-268382
Autor: Campos, Gisélia; Gomides, Maria de Fátima; Baptista, Kleber Eduardo Silva; Franklin, Heloiza Maria de Oliveira Horta; Naveira, Rita Maria Lopes Portocarrero; Nelson, David Lee; Peixoto, Tânia Mara Amâncio Guerra; Ribeiro-Cunha, Mariem Rodrigues; Vieira, Maria Berenice Cardoso Martins.
Título: Verificaçäo do Estado de conservaçäo e da utilizaçäo de sais de propionato em päes de forma / Checking the state of conservation and use of propionic in loaf bread
Fonte: Rev. Inst. Adolfo Lutz;58(2):45-52, jul.-dez.1999. ilus, tab.
Idioma: pt.
Resumo: O ácido propiônico é usado sob a forma de sais de cálcio e sódio como conservador de produtos como chocolate, picles, massas e produtos de confeitaria e panificaçäo, devido à sua propriedade fungicida. Foi feita uma amostragem estatística a partir dos Supermercados e Padaria das 9(nove) regionais de Belo Horizonte: Oeste, Norte, Nordeste, Leste, Venda Nova, Pampulha, Barreiro, Noroeste e Centro Sul. Foram analisadas 191 amostras de päo de forma coletadas pelo Serviço de fiscalizaçäo da Prefeitura Municipal, num total de 24 marcas diferentes. O teor médio encontrado de propionato, expresso em ácido propiônico, foi de 0,13(por cento) com um percentual de reprovaçäo de 12,56(por cento). O método de análise utilizado foi a extraçäo do ácido propiônico com éter e a cromatografia gasosa para a quantificaçäo. Quanto à contagem de bolores e leveduras 12,70(por cento) das 189 amostras analisadas apresentaram resultado acima do limite máximo permitido. A determinaçäo de unidade foi feita em 56 amostras, sendo que 37 66,07(por cento) apresentaram teor acima do permitido pela legislaçäo. As amostras foram analisadas dentro do prazo de validade e foi observada uma variaçäo muito grande deste prazo, até mesmo para uma mesma marca
Descritores: Saccharomyces cerevisiae
Fungicidas Industriais
Propionatos/administração & dosagem
Pão/análise
-Leveduras/isolamento & purificação
Antifúngicos/administração & dosagem
Conservação de Alimentos
Responsável: BR91.2 - Centro de Documentação


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Texto completo SciELO Brasil
Texto completo
Id: biblio-886976
Autor: Ucelli, Juliana Lacerda Reis; Rudolph, Fabiana de Sousa Borges; Obadia, Daniel Lago; Dionello, Carla da Fontoura.
Título: Interstitial granulomatous dermatitis with arthritis
Fonte: An. bras. dermatol;92(3):434-436, May-June 2017. graf.
Idioma: en.
Descritores: Artrite/patologia
Pele/patologia
Dermatite/patologia
Granuloma/patologia
-Artrite/complicações
Artrite/tratamento farmacológico
Propionatos/uso terapêutico
Clobetasol/uso terapêutico
Imageamento por Ressonância Magnética
Reação em Cadeia da Polimerase
Administração Tópica
Dermatite/complicações
Dermatite/tratamento farmacológico
Quimioterapia Combinada
Glucocorticoides/administração & dosagem
Granuloma/complicações
Limites: Humanos
Feminino
Pessoa de Meia-Idade
Tipo de Publ: Relatos de Casos
Carta
Responsável: BR1.1 - BIREME


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Id: biblio-1017382
Autor: Mamimin, Chonticha; Prasertsan, Poonsuk; Kongjan, Prawit; O-Thong, Sompong.
Título: Effects of volatile fatty acids in biohydrogen effluent on biohythane production from palm oil mill effluent under thermophilic condition
Fonte: Electron. j. biotechnol;29:78-85, sept. 2017. tab, graf, ilus.
Idioma: en.
Projeto: Khon Kaen University; . Thailand Research Fund.
Resumo: Background: Biohydrogen effluent contains a high concentration of volatile fatty acid (VFA) mainly as butyric, acetic, lactic and propionic acids. The presence of various VFAs (mixture VFAs) and their cooperative effects on two-stage biohythane production need to be further studied. The effect of VFA concentrations in biohydrogen effluent of palm oil mill effluent (POME) on methane yield in methane stage of biohythane production was investigated. Results: The methane yield obtained in low VFA loading (0.9 and 1.8 g/L) was 15­20% times greater than that of high VFA loading (3.6 and 4.7 g/L). Butyric acid at high concentrations (8 g/L) has the individual significantly negative effect the methane production process (P b 0.05). Lactic, acetic and butyric acid mixed with propionic acid at a concentration higher than 0.5 g/L has an interaction significantly negative effect on the methanogenesis process (P b 0.05). Inhibition condition had a negative effect on both bacteria and archaea with inhibited on Geobacillus sp., Thermoanaerobacterium thermosaccharolyticum, Methanoculleus thermophilus and Methanothermobacter delfuvii resulting in low methane yield. Conclusion: Preventing the high concentration of butyric acid, and propionic acid in the hydrogenic effluent could enhance methane production in two-stage anaerobic digestion for biohythane production.
Descritores: Propionatos/metabolismo
Butiratos/metabolismo
Águas Residuárias/microbiologia
Metano/biossíntese
-Propionatos/análise
Butiratos/análise
Óleo de Palmeira
Methanobacteriaceae
Archaea
Methanomicrobiaceae
Geobacillus
Fermentação
Águas Residuárias/análise
Hidrogênio
Anaerobiose
Responsável: CL1.1 - Biblioteca Central


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Id: biblio-1015999
Autor: Ahmadi, Negin; Khosravi-Darani, Kianoush; Mortazavian, Amir Mohammad.
Título: An overview of biotechnological production of propionic acid: from upstream to downstream processes
Fonte: Electron. j. biotechnol;28:67-75, July. 2017.
Idioma: en.
Resumo: The increasing demand for propionic acid (PA) production and its wide applications in several industries, especially the food industry (as a preservative and satiety inducer), have led to studies on the low-cost biosynthesis of this acid. This paper gives an overview of the biotechnological aspects of PA production and introduces Propionibacterium as the most popular organism for PA production. Moreover, all process variables influencing the production yield, different simple and complex carbon sources, the metabolic pathway of production, engineered mutants with increased productivity, and modified tolerance against high concentrations of acid have been described. Furthermore, possible methods of extraction and analysis of this organic acid, several applied bioreactors, and different culture systems and substrates are introduced. It can be concluded that maximum biomass and PA production may be achieved using metabolically engineered microorganisms and analyzing the most significant factors influencing yield. To date, the maximum reported yield for PA production is 0.973 g·g-1, obtained from Propionibacterium acidipropionici in a three-electrode amperometric culture system in medium containing 0.4 mM cobalt sepulchrate. In addition, the best promising substrate for PA bioproduction may be achieved using glycerol as a carbon source in an extractive continuous fermentation. Simultaneous production of PA and vitamin B12 is suggested, and finally, the limitations of and strategies for competitive microbial production with respect to chemical process from an economical point of view are proposed and presented. Finally, some future trends for bioproduction of PA are suggested.
Descritores: Propionatos/metabolismo
Propionibacterium/metabolismo
-Propionatos/química
Vitamina B 12/biossíntese
Carbono/metabolismo
Reatores Biológicos
Ácidos Graxos Voláteis/metabolismo
Fermentação
Concentração de Íons de Hidrogênio
Nitrogênio/metabolismo
Tipo de Publ: Revisão
Responsável: CL1.1 - Biblioteca Central


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Id: biblio-1009760
Autor: Zielinska, Krystyna; Fabiszewska, Agata; Swiatek, Michal; Szymanowska-Powalowska, Daria.
Título: Evaluation of the ability to metabolize 1, 2-propanediol by heterofermentative bacteria of the genus Lactobacillus
Fonte: Electron. j. biotechnol;26:60-63, Mar. 2017. ilus, ilus.
Idioma: en.
Resumo: Background: New directions of research on lactic acid bacteria include investigation of metabolic pathways for the synthesis and/or metabolism of 1,2-propanediol, commonly used in the food and chemical industry, medicine, pharmacy and cosmetology as well as agriculture. The objective of this study was to compare the capacity of strains representing three diverse heterofermentative species belonging to the genus Lactobacillus to synthesize and/or transform 1,2-PD as well as to suggest new directions of research aimed at commercial use of this metabolite. Results: The novel strain of Lactobacillus buchneri A KKP 2047p, characterized as exhibiting an unusual trait for that species in the form of capacity to metabolize 1,2-PD, grew poorly in a medium containing 1,2-PD as a sole carbon source. The supplementation with glucose facilitated rapid growth of bacteria and use of 1,2-PD for the synthesis of propionic acid. A similar observation was noted for Lactobacillus reuteri. On the other hand, Lactobacillus diolivorans effectively metabolized 1,2-PD which was the sole carbon source in the medium, and the addition of glucose inhibited the synthesis of propionic acid. The experiments also investigated the effect of cobalamin as a diol dehydratase coenzyme involved in the propionic acid synthesis from 1,2-PD whose addition promoted the yield of the reaction in the case of all tested strains. Conclusions: All tested isolates showed the ability to effectively metabolize 1,2-PD (in the presence of cobalamin) and its conversion to propionic acid, which reveals that investigated bacteria meet the essential requirements of microorganisms with a potential application.
Descritores: Propilenoglicol/metabolismo
Lactobacillus/metabolismo
-Propionatos
Vitamina B 12/metabolismo
Ácido Láctico
Propilenoglicol/síntese química
Fermentação
Glucose
Responsável: CL1.1 - Biblioteca Central


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Id: biblio-1005289
Autor: Calderón, Constanza; Gennaro Noferi, María Eugenia; Romero Orellano, Fernando.
Título: Efecto de los corticoesteroides intranasales tópicos en los valores de eosinófilos en mucosa nasal en pacientes adultos con rinitis alérgica / Effect of topical intranasal corticosteroids on eosinophil values in nasal mucosa in adult patients with allergic rhinitis / Efeito dos corticosteróides intranasais tópicos nos valores de eosinófilos na mucosa nasal em pacientes adultos com rinite alérgica
Fonte: Rev. Fed. Argent. Soc. Otorrinolaringol;25(1):50-54, 2018. graf.
Idioma: es.
Resumo: INTRODUCCIÓN: La citología nasal es utilizada como método complementario diagnóstico de la rinitis y el hallazgo de eosinófilos; en la misma aumenta la sensibilidad para confirmar una alergia a casi el 80%. Los corticoesteroides intranasales tópicos se utilizan actualmente como primera línea de tratamiento de la rinitis porque reducen la inflamación de la mucosa que subyace a los signos y síntomas de la enfermedad. MATERIAL Y MÉTODOS: Estudio observacional, retrospectivo y analítico. Se incluyeron pacientes entre 16 a 65 años edad inclusive, que consultaron al Servicio de Otorrinolaringología y Alergia e Inmunología de la Clínica Universitaria Reina Fabiola entre agosto de 2016 y julio de 2017 con diagnóstico de rinitis alérgica. La información de las variables cuantitativas se sometió a una comprobación estadística realizada mediante el test de Wilcoxon apareado. Se consideró significativo un valor de p<0,05…

INTRODUCTION: Nasal cytology is used as a complementary diagnostic method of rhinitis and the finding of eosinophils in it increases the sensitivity to confirm an allergy to almost 80%. Topical intranasal corticosteroids are currently used as the first line of treatment for rhinitis because they reduce the inflammation of the mucosa that underlies the signs and symptoms of the disease. MATERIAL AND METHODS: Observational, retrospective and analytical study. Patients between the ages of 16 and 65 years were included, who consulted the Otorhinolaryngology and Allergy and Immunology Department of the Reina Fabiola University Clinic between August 2016 and July 2017 with a diagnosis of allergic rhinitis. The information of the quantitative variables was subjected to a statistical check carried out by means of the paired Wilcoxon test. A value of p...
Descritores: Corticosteroides/uso terapêutico
Eosinófilos/efeitos dos fármacos
Rinite Alérgica/imunologia
Mucosa Nasal/citologia
-Propionatos/uso terapêutico
Estudos Retrospectivos
Citodiagnóstico/estatística & dados numéricos
Estudo Observacional
Rinite Alérgica/tratamento farmacológico
Furoato de Mometasona/uso terapêutico
Limites: Adolescente
Adulto
Responsável: AR635.1 - FCVyS - Servicio de Información y Documentación


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Id: biblio-907655
Autor: Barrera M., Francisco.
Título: Nuevas estrategias farmacológicas para el tratamiento del hígado graso no alcohólico / New pharmacological strategies for the treatment of non-alcoholic fatty liver disease
Fonte: Gastroenterol. latinoam;27(supl.1):S55-S59, 2016. ilus, tab, graf.
Idioma: es.
Resumo: Non-alcoholic fatty liver disease (NAFLD) represents an increasing health problem in Chile and worldwide. In some cases NAFLD presents with a progressive form that can lead to liver fibrosis, cirrhosis and hepatocellular carcinoma. Current pharmacological therapies (pioglitazone and vitamin E) show limited response and are associated to significant adverse effects. During recent years several novel and promising pharmacological therapies have been developed to prevent fibrosis, liver cirrhosis and reduce liver related deaths. The present article summarizes some of these promising strategies, including reported efficacy in clinical trials and associated adverse effects. Hopefully in the near future these new therapies will help to improve NAFLD management and reduce liver related complications.

El hígado graso no alcohólico (HGNA) es un creciente problema de salud pública en Chile y el mundo. En un subgrupo de sujetos, el HGNA puede presentarse con un fenotipo de daño hepático progresivo que puede evolucionar a fibrosis progresiva, cirrosis y carcinoma hepatocelular. Las estrategias farmacológicas actuales (pioglitazona y vitamina E) presentan eficacia limitada y no están exentas de efectos adversos. Durante los últimos años se han desarrollado múltiples estrategias farmacológicas novedosas y promisorias que buscan evitar la progresión hacia cirrosis y reducir la mortalidad de causa hepática. El presente artículo resume los principales nuevos fármacos, los efectos beneficiosos reportados y sus efectos adversos. Es de esperar que en un futuro próximo estas terapias permitan cambiar el pronóstico de nuestros pacientes con HGNA.
Descritores: Ácido Quenodesoxicólico/análogos & derivados
Ácido Quenodesoxicólico/uso terapêutico
Liraglutida/uso terapêutico
Hepatopatia Gordurosa não Alcoólica/tratamento farmacológico
Propionatos/uso terapêutico
-Chalconas/uso terapêutico
Cirrose Hepática/prevenção & controle
Limites: Humanos
Responsável: CL61.1 - Biblioteca Central Campus Sur



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