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Id: biblio-1253015
Autor: Usta-Gorgun, Buse; Yilmaz-Ersan, Lutfiye.
Título: Short-chain fatty acids production by Bifidobacterium species in the presence of salep
Fonte: Electron. j. biotechnol;47:29-35, sept. 2020. tab, graf.
Idioma: en.
Projeto: Commission of Scientific Research Projects of Bursa Uludag University, Bursa, Turkey.
Resumo: BACKGROUND: Salep is obtained by grinding dried orchid tubers and used as a valuable ingredient in the food industry. Because of the glucomannan content of salep, it is thought to have prebiotic potential. However, there is little information in studies concerning the fermentation characteristics and potential prebiotic properties of salep. The objective of this study was to investigate the effect of salep on bifidobacterial growth by measuring the highest optical density (OD), calculating the specific growth rates, and determining the production of lactic acid and short-chain fatty acids (acetic, propionic, and butyric acid) as a result of bacterial fermentation. RESULT: The OD and pH values obtained in this study showed that salep was utilized as a source of assimilable carbon and energy by the Bifidobacterium species (BS). All Bifidobacterium strains produced lactic, acetic, propionic, and butyric acid, indicating that salep is readily fermented by these bacteria. Salep at 1% (w/v) showed a similar effect on bifidobacterial growth as that promoted by 1% (w/v) glucose used as a traditional carbon source. CONCLUSIONS: Bifidobacterium species can develop in media containing salep as well as in glucose and exhibit the potential to be used as new sources of prebiotics.
Descritores: Pós/metabolismo
Bifidobacterium/crescimento & desenvolvimento
Bifidobacterium/metabolismo
Ácidos Graxos Voláteis/biossíntese
-Propionatos/análise
Propionatos/metabolismo
Indústria Alimentícia
Ácido Acético/análise
Ácido Acético/metabolismo
Ácido Láctico/análise
Ácido Láctico/metabolismo
Probióticos
Ácido Butírico/análise
Ácido Butírico/metabolismo
Ácidos Graxos Voláteis/análise
Prebióticos
Fermentação
Concentração de Íons de Hidrogênio
Responsável: CL1.1 - Biblioteca Central


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Id: biblio-886348
Autor: Londoño, Jessica María; Niño, Cesar Daniel; Díaz, James; Morales, Carlos; León, Jimmy P; Bernal, Elisa; Mejía, Leonardo; Caraballo, Cesar; Garcés, Daniela; Hincapié, Carolina; Ascuntar, Johana; León, Alba L; Jaimes, Fabián A.
Título: Asociación de variables clínicas de hipoperfusión con el lactato y la mortalidad / Association of clinical variables of hypoperfusion with lactate and mortality
Fonte: Acta méd. colomb;42(2):97-105, abr.-jun. 2017. tab, graf.
Idioma: es.
Resumo: Resumen Introducción: entre los pacientes con infección la hiperlactatemia identifica una población de mayor gravedad. Este estudio pretende determinar en pacientes de urgencias la correlación y asociación entre los parámetros clínicos de perfusión y los valores de lactato en el momento de admisión; así como el cambio en los parámetros clínicos con la depuración del lactato. Además, determinar la asociación entre estas variables y la mortalidad intrahospitalaria. Métodos: cohorte prospectiva de pacientes que ingresaron con sospecha de infección a un hospital de tercer nivel. Se midió el lactato en la admisión a las 6 y 24 horas, concomitantemente con las variables llenado capilar, índice de choque y presión de pulso, entre otras. Se realizó correlación de Spearman entre las variables clínicas, los niveles de lactato y su depuración; así como curvas ROC para determinar la capacidad discriminativa de las variables clínicas para detectar hiperlactatemia. Se realizó un modelo de regresión logística multivariable para mortalidad. Resultados: se evaluaron 2257 pacientes, 651 correspondían a infección confirmada. No se encontró ninguna correlación de utilidad entre las variables clínicas y el lactato (r<0.25); y tampoco se detectó adecuada capacidad discriminativa para la detección de hiperlactatemia con ninguna variable clínica (AUC<0.61). En el modelo de regresión logística multivariada el valor del lactato al ingreso fue la única variable que se asoció de manera independiente con mortalidad (OR=1.4, IC95%=1.3-1.6). Conclusiones: entre los pacientes que ingresan a urgencias con infección no se encontró correlación entre las variables clínicas y el lactato; sin embargo, el lactato al ingreso es un marcador pronóstico independiente de mortalidad. (Acta Med Colomb 2017: 42: 97-105).

Abstract Introduction: among patients with infection, hyperlactatemia identifies a population of greater severity. This study aims to determine the correlation and association between clinical perfusion parameters and lactate values in emergency patients at the time of admission, as well as the change in clinical parameters with lactate clearance. In addition, to determine the association between these variables and in-hospital mortality. Methods: Prospective cohort of patients admitted with suspected infection to a third level hospital. Lactate was measured at admission, at 6 and 24 hours, concomitantly with the variables capillary filling, shock index and pulse pressure, among others. Among the clinical variables, Spearman correlation, lactate levels and their clearance, as well as ROC curves to determine the discriminative ability of clinical variables to detect hyperlactatemia were performed. A multivariate logistic regression model for mortality was carried out. Results: 2257 patients were evaluated. 651 were confirmed with infections. No utility correlation was found between clinical variables and lactate (r <0.25), and no discriminative capacity was detected for the detection of hyperlactatemia with any clinical variable (AUC <0.61). In the multivariate logistic regression model the lactate value at admission was the only variable that was independently associated with mortality (OR = 1.4, 95% CI = 1.3-1.6). Conclusions: no correlation was found between clinical variables and lactate among patients admitted to the emergency department with infection; however lactate at admission is an independent prognostic marker of mortality. (Acta Med Colomb 2017: 42: 97-105).
Descritores: Ácido Láctico
-Perfusão
Choque
Determinação
Infecções
Limites: Humanos
Masculino
Feminino
Adolescente
Responsável: CO70 - Asociación Colombiana de Medicina Interna


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Id: biblio-974927
Autor: Machado, Alexandre F; Evangelista, Alexandre L; Miranda, João Marcelo Q; Teixeira, Cauê V La Scala; Rica, Roberta Luksevicius; Lopes, Charles R; Figueira-Júnior, Aylton; Baker, Julien S; Bocalini, Danilo S.
Título: Description of training loads using whole-body exercise during high-intensity interval training
Fonte: Clinics;73:e516, 2018. tab, graf.
Idioma: en.
Resumo: OBJECTIVES: To describe external training load and internal training load through sets of a single session of high-intensity interval training (HIIT) body work. METHODS: Twenty male individuals (24±3 years) performed a HIIT body work protocol consisting of a single bout of exercise with 1:1 stimuli. The exercises used were 30 min in duration with "all-out" intensity. The exercises included jumping jacks, mountain climbers, burpees and squat jumps, totaling 20 min of exercise. During exercise, total movement capacity, blood lactate measurement, ratings of perceived exertion and recovery, training load and intensity were monitored. RESULTS: The single bout examined showed a total of 382±89 movements. Differences (p<0.01) in the total amount of movement for each exercise were noted, reflecting the difficulty of maintaining exercise over time. Increases in lactate concentrations (before: 0.98±0.16, after: 14.10±1.66; mmol/L) were found postexercise. Significant differences (p<0.01) were found after the fifth set, and the values for movement capacity remained higher than the values of the first set, demonstrating high load in a single session. No differences in ratings of perceived exertion (RPE) during the sets were found. However, the ratings of perceived recuperation from the second set were significantly (p<0.01) lower than those from the first set. CONCLUSIONS: The exercise protocol used in this study was of high intensity and produced large values for stress during performance, with increases recorded for the internal load indicators.
Descritores: Consumo de Oxigênio/fisiologia
Treinamento de Força
Treinamento Intervalado de Alta Intensidade
Frequência Cardíaca/fisiologia
-Ácido Láctico/sangue
Esforço Físico/fisiologia
Limites: Humanos
Masculino
Adulto Jovem
Responsável: BR1.1 - BIREME


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Id: biblio-1130586
Autor: Bocio, Cleo Irene; García, Johana Aylen; Dotto, Gladys; Roch, Florencia Graciela; Neme Mazzuchi, Viviana Noelia; Jachuf, Carolina; Torres, María Lía.
Título: Comparación de dos tipos de recipientes para analizar gases en sangre y otras mediciones relacionadas contra jeringas con heparinato de litio liofilizado / Comparison of two types of containers to analyze blood gases and other related measurements against syringes with lyophilized lithium heparinate / Comparação de dois tipos de recipientes para analisar gases em sangue e outras medições relacionadas contra seringas com heparinato de lítio liofilizado
Fonte: Acta bioquím. clín. latinoam;54(2):117-124, jun. 2020. graf, tab.
Idioma: es.
Resumo: El estudio de gases en sangre involucra pruebas relacionadas con el equilibrio ácido-base y estado de oxigenación (pH, pO2, SO2, pCO2, HCO3 -). Además, en los equipos multiparamétricos se realizan otras determinaciones (mediciones relacionadas) como: Na+, K+, Cl-, Ca2+, glucosa y lactato. El objetivo de este trabajo fue comparar los resultados de medición de dos tipos de recipientes (tipo 2: jeringa preparada en el laboratorio con heparinato de Na+ líquido diluido y tipo 3: microtubo con heparinato de Li líquido) contra el recipiente recomendado por el CLSI en su guía 46-A2 (tipo 1: jeringa con heparinato de Li liofilizado balanceado con zinc). El análisis se hizo desde un punto de vista estadístico y clínico para establecer la posibilidad de usar indistintamente estos tres tipos de recipientes. Se analizaron un total de 254 muestras. Para evaluar la aceptación clínica de los resultados se tomó como estándar de calidad la variabilidad biológica. No se encontraron diferencias clínicamente significativas en los analitos del recipiente tipo 2 respecto del tipo 1, excepto para Ca2+. Se rechazaron desde el punto de vista clínico varios analitos del recipiente tipo 3. En conclusión, el uso del recipiente tipo 3 fue inapropiado. Sin embargo, el recipiente tipo 2 sería apto para el análisis de este tipo de muestras.

Blood gas analysis involves tests related to the acid-base balance and oxygenation state (pH, pO2, SO2, pCO2, HCO3 -). In multiparametric equipment, some ion and metabolite (related measurements) are performed: Na+, K+, Cl-, Ca²+, glucose and lactate. The objective of this study was to compare two types of containers (type 2: syringe prepared in the laboratory with diluted liquid sodium heparinate and type 3: microtube with liquid lithium heparinate) against the container recommended by CLSI in its guide 46-A2 (type 1: syringe with lyophilized lithium heparinate balanced with inc). The analysis was made from a statistical and clinical point of view to establish the possibility of indiscriminately using these three types of containers. A total of 254 samples were analyzed. To establish the clinical acceptance of the results, the biological variability quality standard was used. No clinically significant differences were found in the analytes of the type 2 container compared to type 1, except for Ca+. Several analytes of the type 3 container were rejected from the clinical point of view. In conclusion, the use of the type 3 container is inappropriate; however, the type 2 container would be suitable for the analysis of this type of samples.

O estudo de gases em sangue envolve testes relacionados com o equilíbrio ácido-base e estado de oxigenação (pH, pO2, SO2, pCO2, HCO3 -). Além disso, nos equipamentos multiparâmetros, outras determinações (medições relacionadas) como: Na+ , K+, Cl-, Ca2+, glicose e lactato são realizadas. O objetivo deste trabalho foi comparar os resultados de medição de dois tipos de recipientes (tipo 2: seringa preparada no laboratório com heparinato de Na+ líquido diluído e tipo 3: microtubo com heparinato de Li líquido) contra o recipiente recomendado pelo CLSI em seu guia 46-A2 (tipo 1: seringa com heparinato de Li liofilizado equilibrado com zinco). A análise foi feita do ponto de vista estatístico e clínico, para estabelecer a possibilidade de utilização indiscriminada desses três tipos de recipientes. Um total de 254 amostras foram analisadas. Para avaliar a aceitação clínica dos resultados, a variabilidade biológica foi tomada como padrão de qualidade. Não foram encontradas diferenças clinicamente significativas nos analitos do recipiente tipo 2 em relação ao tipo 1, exceto para Ca²+. Vários analitos do recipiente tipo 3 foram rejeitados do ponto de vista clínico. Em conclusão, o uso do contêiner tipo 3 foi inadequado. No entanto, o recipiente tipo 2 seria apto para a análise deste tipo de amostras.
Descritores: Seringas
Equilíbrio Ácido-Base
Gasometria
Gestão da Qualidade
Concentração de Íons de Hidrogênio
-Sódio
Zinco
Medidas, Métodos e Teorias
Sangue
Ácido Láctico
Estado
Equipamentos e Provisões
Gases
Glucose
Laboratórios
Limites: Humanos
Masculino
Feminino
Adulto
Pessoa de Meia-Idade
Idoso
Idoso de 80 Anos ou mais
Responsável: AR144.1 - CIBCHACO - Centro de Información Biomedica del Chaco


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Id: biblio-843475
Autor: Ramani, Jaydip; Malhotra, Amber; Wadhwa, Vivek; Sharma, Pranav; Garg, Pankaj; Tarsaria, Malkesh; Pandya, Himani.
Título: Single-dose lignocaine-based blood cardioplegia in single valve replacement patients
Fonte: Rev. bras. cir. cardiovasc = Braz. j. cardiovasc. surg. (impr.);32(2):90-95, Mar.-Apr. 2017. tab.
Idioma: en.
Resumo: Abstract OBJECTIVE: Myocardial protection is the most important in cardiac surgery. We compared our modified single-dose long-acting lignocaine-based blood cardioplegia with short-acting St Thomas 1 blood cardioplegia in patients undergoing single valve replacement. METHODS: A total of 110 patients who underwent single (aortic or mitral) valve replacement surgery were enrolled. Patients were divided in two groups based on the cardioplegia solution used. In group 1 (56 patients), long-acting lignocaine based-blood cardioplegia solution was administered as a single dose while in group 2 (54 patients), standard St Thomas IB (short-acting blood-based cardioplegia solution) was administered and repeated every 20 minutes. All the patients were compared for preoperative baseline parameters, intraoperative and all the postoperative parameters. RESULTS: We did not find any statistically significant difference in preoperative baseline parameters. Cardiopulmonary bypass time were 73.8±16.5 and 76.4±16.9 minutes (P=0.43) and cross clamp time were 58.9±10.3 and 66.3±11.2 minutes (P=0.23) in group 1 and group 2, respectively. Mean of maximum inotrope score was 6.3±2.52 and 6.1±2.13 (P=0.65) in group 1 and group 2, respectively. We also did not find any statistically significant difference in creatine-phosphokinase-MB (CPK-MB), Troponin-I levels, lactate level and cardiac functions postoperatively. CONCLUSION: This study proves the safety and efficacy of long-acting lignocaine-based single-dose blood cardioplegia compared to the standard short-acting multi-dose blood cardioplegia in patients requiring the single valve replacement. Further studies need to be undertaken to establish this non-inferiority in situations of complex cardiac procedures especially in compromised patients.
Descritores: Soluções Cardioplégicas/administração & dosagem
Implante de Prótese de Valva Cardíaca/métodos
Parada Cardíaca Induzida/métodos
Lidocaína/administração & dosagem
-Valva Aórtica/cirurgia
Período Pós-Operatório
Cloreto de Potássio/administração & dosagem
Bicarbonatos/administração & dosagem
Cloreto de Cálcio/administração & dosagem
Cloreto de Sódio/administração & dosagem
Estudos Prospectivos
Resultado do Tratamento
Ácido Láctico/sangue
Troponina I/sangue
Creatina Quinase/sangue
Magnésio/administração & dosagem
Valva Mitral/cirurgia
Limites: Humanos
Masculino
Feminino
Adolescente
Adulto
Pessoa de Meia-Idade
Adulto Jovem
Tipo de Publ: Ensaio Clínico Controlado Aleatório
Responsável: BR1.1 - BIREME


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Id: biblio-958414
Autor: Nasrala, Mara L S; Bolzan, Douglas W; Lage, Yumi G; Prado, Fabiana S; Arena, Ross; Lima, Paulo R L; Feguri, Gibran; Silva, Ageo M C; Marcondi, Natasha O; Hossne, Nelson; Guizilini, Solange; Gomes, Walter J.
Título: Extended-time of noninvasive positive pressure ventilation improves tissue perfusion after coronary artery bypass surgery: a randomized clinical trial
Fonte: Rev. bras. cir. cardiovasc = Braz. j. cardiovasc. surg. (impr.);33(3):250-257, May-June 2018. tab, graf.
Idioma: en.
Resumo: Abstract Objective: To compare the effects of extended- versus short-time noninvasive positive pressure ventilation on pulmonary function, tissue perfusion, and clinical outcomes in the early postoperative period following coronary artery bypass surgery in patients with preserved left ventricular function. Methods: Patients were randomized into two groups according to noninvasive positive pressure ventilation intensity: short-time noninvasive positive pressure ventilation n=20 (S-NPPV) and extended-time noninvasive positive pressure ventilation n=21 (E-NPPV). S-NPPV was applied for 60 minutes during immediate postoperative period and 10 minutes, twice daily, from postoperative days 1-5. E-NPPV was performed for at least six hours during immediate postoperative period and 60 minutes, twice daily, from postoperative days 1-5. As a primary outcome, tissue perfusion was determined by central venous oxygen saturation and blood lactate level measured after anesthetic induction, immediately after extubation and following noninvasive positive pressure ventilation protocols. As a secondary outcome, pulmonary function tests were performed preoperatively and in the postoperative days 1, 3, and 5; clinical outcomes were recorded. Results: Significant drop in blood lactate levels and an improvement in central venous oxygen saturation values in the E-NPPV group were observed when compared with S-NPPV group after study protocol (P<0.01). The E-NPPV group presented higher preservation of postoperative pulmonary function as well as lower incidence of respiratory events and shorter postoperative hospital stay (P<0.05). Conclusion: Prophylactic E-NPPV administered in the early postoperative period of coronary artery bypass surgery resulted in greater improvements in tissue perfusion, pulmonary function and clinical outcomes than S-NPPV, in patients with preserved left ventricular function. Trial Registration: Brazilian Registry of Clinical trial - RBR7sqj78 - http://www.ensaiosclinicos.gov.br
Descritores: Ponte de Artéria Coronária/métodos
Respiração com Pressão Positiva/métodos
Ventilação não Invasiva/métodos
Pneumopatias/prevenção & controle
-Oxigênio/sangue
Complicações Pós-Operatórias/prevenção & controle
Complicações Pós-Operatórias/sangue
Fatores de Tempo
Capacidade Vital
Volume Expiratório Forçado
Ponte de Artéria Coronária/efeitos adversos
Fatores de Risco
Análise de Variância
Resultado do Tratamento
Estatísticas não Paramétricas
Ácido Láctico/sangue
Tempo de Internação
Pneumopatias/etiologia
Pneumopatias/sangue
Limites: Humanos
Masculino
Feminino
Pessoa de Meia-Idade
Idoso
Tipo de Publ: Ensaio Clínico Controlado Aleatório
Responsável: BR1.1 - BIREME


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Id: biblio-990568
Autor: Cantero, Marcos Antonio; Almeida, Rui Manuel Siqueira; Morato, Priscila Neder; Santos-Junior, Valfredo de Almeida; Moura, Carolina Soares; Amaya-Farfan, Jaime; Fonseca, João Luis; Lollo, Pablo Christiano Barboza.
Título: The expression of and preoperative correlation between heat-shock protein 70, euroscore, and lactate in patients undergoing cabg with cardiopulmonary bypass
Fonte: Rev. bras. cir. cardiovasc = Braz. j. cardiovasc. surg. (impr.);34(2):156-164, Mar.-Apr. 2019. tab, graf.
Idioma: en.
Resumo: Abstract Objetive: Coronary artery bypass grafting (CABG) with cardiopulmonary bypass (CPB) improved symptoms and increased survival and quality of life in patients with coronary artery disease. However, it should be the main cause of a complex organic systemic inflammatory response that greatly contributes to several postoperative adverse effects. Methods: We aimed to evaluate heat-shock protein 70 (HSP 70) expression as a morbimortality predictor in patients with preserved ventricular function undergoing coronary artery bypass grafting (CABG) with cardiopulmonary bypass (CPB) and to determine their association with the lactate as a marker of tissue hypoperfusion and the EuroSCORE risk score. This is a prospective, observational study including 46 patients and occurring between May and July 2016. Patients without ventricular dysfunction undergoing myocardial revascularization with extracorporeal circulation were included. They were divided into (1) complicated and (2) uncomplicated postoperative evolution groups. EuroSCORE, lactate levels, and HSP 70 expression and their correlations were determined. Results: Statistical analysis showed that the group with complicated evolution had higher EuroSCORE values than the other group. HSP 70 protein levels were significantly increased in the group with uncomplicated evolution and showed similar results. According to our results, HSP family proteins may be independent predictors of uncomplicated evolution in patients without ventricular dysfunction undergoing CABG with CPB. Conclusion: HSP 70 should be a good discriminator and protection marker for complications in cardiac surgery.
Descritores: Ponte Cardiopulmonar/mortalidade
Ponte de Artéria Coronária/mortalidade
Medição de Risco/métodos
Proteínas de Choque Térmico HSP70/análise
Ácido Láctico/sangue
Período Pré-Operatório
-Complicações Pós-Operatórias/etiologia
Biomarcadores/análise
Ponte Cardiopulmonar/métodos
Modelos Logísticos
Western Blotting
Ponte de Artéria Coronária/métodos
Sensibilidade e Especificidade
Estatísticas não Paramétricas
Miocárdio/patologia
Limites: Humanos
Masculino
Feminino
Adulto
Pessoa de Meia-Idade
Idoso
Idoso de 80 Anos ou mais
Tipo de Publ: Estudo Observacional
Responsável: BR1.1 - BIREME


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Id: biblio-1020500
Autor: Harky, Amer; Fok, Matthew; Fraser, Holly; Howard, Callum; Rimmer, Lara; Bashir, Mohamad.
Título: Could cerebrospinal fluid biomarkers offer better predictive value for spinal cord ischaemia than current neuromonitoring techniques during thoracoabdominal aortic aneurysm repair - a systematic review
Fonte: Rev. bras. cir. cardiovasc = Braz. j. cardiovasc. surg. (impr.);34(4):464-471, July-Aug. 2019. tab.
Idioma: en.
Resumo: Abstract Objective: Cerebrospinal fluid (CSF) drainage is a technique that has significantly reduced the incidence of spinal cord ischaemia (SCI). We present results of a systematic review to assess the literature on this topic in relation to thoracoabdominal aortic aneurysm repair (TAAR). Methods: Major medical databases were searched to identify papers related to CSF biomarkers measured during TAAAR. Results: Fifteen papers reported measurements of CSF biomarkers with 265 patients in total. CSF biomarkers measured included S-100ß, neuron-specific endolase (NSE), lactate, glial fibrillary acidic protein A (GFPa), Tau, heat shock protein 70 and 27 (HSP70, HSP27), and proinflammatory cytokines. Lactate and S-100ß were reported the most, but did not correlate with SCI, which was also the case with NSE and TAU. GFPa showed significant CSF level rises, both intra and postoperative in patients who suffered SCI and warrants further investigation, similar results were seen with HSP70, HSP27 and IL-8. Conclusions: Although there is significant interest in this topic, there still remains a significant lack of high-quality studies investigating CSF biomarkers during TAAR to detect SCI. A large and multicentre study is required to identify the significant role of each biomarker.
Descritores: Fosfopiruvato Hidratase/sangue
Biomarcadores/líquido cefalorraquidiano
Aneurisma da Aorta Torácica/cirurgia
Isquemia do Cordão Espinal/líquido cefalorraquidiano
Técnicas Eletroquímicas/métodos
-Biomarcadores/sangue
Proteínas S100/líquido cefalorraquidiano
Proteínas S100/sangue
Drenagem
Ácido Láctico/líquido cefalorraquidiano
Ácido Láctico/sangue
Isquemia do Cordão Espinal/sangue
Limites: Humanos
Tipo de Publ: Revisão Sistemática
Responsável: BR1.1 - BIREME


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Id: lil-620402
Autor: Silva, Soraia Micaela; Corrêa, João Carlos Ferrari; Amaral, Tatiane Soares; Pereira, Henrique Ângelo Nunes; Jerônimo, Jéssica Cândido; Sampaio, Luciana Maria Malosá; Corrêa, Fernanda Ishida.
Título: Dosagem da fadiga muscular, pela análise do ácido láctico e da força muscular, após dois protocolos de estimulação elétrica funcional em indivíduos portadores de AVE / Determination of muscle fatigue, through analysis of lactate and muscle strength after two protocols of functional electrical stimulation in individuals with stroke
Fonte: Rev. Ter. Man;8(36):126-131, mar.-abr. 2010. graf.
Idioma: pt.
Resumo: Fortalecimento da musculatura parética promove melhora da capacidade funcional, o que pode ser obtido pela estimulação elétrica funcional (FES), porém são necessários treinamento e parâmetros específicos a fim de se evitar a fadiga. Objetivo: Este trabalho, no intuito de melhor compreendermos um desses parâmetros de estimulação elétrica, a freqüência, objetivou verificar o aparecimento da fadiga muscular em indivíduos hemiparéticos, decorrentes do AVE. Método: Foram coletadas amostras de sangue de 18 indivíduos, portadores de hemiparesia, em sete momentos: repouso/pré-tratamento, após cada uma das três séries de 15 repetições de estimulação, e no 30, 60 e90 minuto subseqüentes ao término da terapia, além da avaliação da contração voluntária máxima isométrica (CVMI),coletado por meio da célula de carga em Kg/força, do músculo bíceps braquial. Utilizou-se uma corrente quadrada e bifásica, com t"on" de 10 seg., e t"off" de 30 seg., e freqüência variável de 50 Hz (protocolo 1) e 2.000Hz (protocolo2), sobre o ponto motor do músculo bíceps braquial. Resultados: Foi observado que não houve diferença estatisticamente significante (p
Reinforcement of the paretic muscles promotes improvement of the functional capacity, what it can be gotten by the functional electric stimulation (FES), however is necessary training and specific parameters in order to prevent the fatigue. Objective: This work, in the intention of better understanding one of these parameters of electric stimulation, the frequency, objectified to verify the appearance of the muscular fatigue in hemiparetics, post stroke. Methods: Samples of blood of 18 individuais had been collected, hemiparetic individuais, at seven moments: rest/ pre-treatment, after each one of the three series of 15 repetitions of stimulation, and in 3º, 6º and 9º minute subsequent to the ending of the therapy, and evaluation of the maximum contraction isometric voluntary (MCIV), collected by means of the cell of load in kg/force, on the brachiallis bicepc muscle. A square shaped and two-phase chain was used, with 10 second of t"on", and t" off" of 30 sec., and frequency change able of 50 Hz ( protocol 1) and 2.000Hz ( protocol 2), on the motor point of brachiallis biceps muscle.
Descritores: Acidente Vascular Cerebral
Estimulação Elétrica
Fadiga Muscular
Ácido Láctico
Limites: Humanos
Masculino
Feminino
Adulto
Responsável: BR512.1 - Biblioteca Setorial do Centro de Ciências da Saúde


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Id: biblio-1132191
Autor: Fernandes, Maria Thereza Carlos; Guergoletto, Karla Bigetti; Watanabe, Lycio Shinji; Nixdorf, Suzana Lucy; Oliveira, Admilton Gonçalves de; Garcia, Sandra.
Título: Milk with Juçara (Euterpe edulis Martius) Pulp: Fermentation by L. reuteri LR92 and Reuterin Production in Situ
Fonte: Braz. arch. biol. technol;63:e20190286, 2020. tab, graf.
Idioma: en.
Projeto: Coordenação de Aperfeiçoamento de Pessoal de Nível Superior.
Resumo: Abstract This study aimed to develop and evaluate fermented milk by Lactobacillus reuteri LR92 with addition of juçara pulp (FMJ) and reuterin production in situ. The fermentation process was analyzed for 24 hours and the storage of FMJ for 30 days at 4 °C. During the fermentation, there was consumption of 25% (w / v) of lactose and increase of 0.01 to 0.85% (w / v) of lactic acid. The FMJ presented 0.43 ± 0.01 mM of reuterin, inhibiting Staphylococcus aureus strains under in vitro test. For the carbohydrates, the percentages (g.100g-1) found were 7.31 ± 1.07; 9.19 ± 0.82; 1.60 ± 0.50 and 0.08 ± 0.00 for sucrose, lactose, galactose and fructose respectively. The survival of L. reuteri, present in FMJ, was 2.47 log CFU / mL after 6 hours of gastrointestinal simulation. In sensory analysis FMJ received a grade 7 for global acceptance indicating good acceptance of the product.
Descritores: Produtos Fermentados do Leite/microbiologia
Alimento Funcional/microbiologia
Lactobacillus reuteri/metabolismo
Euterpe/metabolismo
-Propano/metabolismo
Staphylococcus aureus/efeitos dos fármacos
Ácido Láctico
Anti-Infecciosos
Limites: Animais
Responsável: BR1.1 - BIREME



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