Base de dados : LILACS
Pesquisa : D02.455.326.397.300 [Categoria DeCS]
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Texto completo SciELO Brasil
Abrahäo, Márcio
Texto completo
Id: lil-775568
Autor: Melo, Giulianno Molina de; Cervantes, Onivaldo; Covolan, Luciene; Baptista, Heloisa Allegro; Ferreira, Elenn Soares; Abrahao, Marcio.
Título: Facial nerve identification with fluorescent dye in rats
Fonte: Acta cir. bras;31(2):92-102, Feb. 2016. tab, graf.
Idioma: en.
Resumo: PURPOSE The parotidectomy technique still has an elevated paresis and paralysis index, lowering patient life's quality. The correct identification of the facial nerve can prevent nerve damage. Fluorescent dye identifies nerves in experimental studies but only few articles focused its use on facial nerve study in parotidectomies. We aimed to stain the rat facial nerve with fluorescent dye to facilitate visualization and dissection in order to prevent injuries. METHODS Forty adult male Wistar rats were submitted to facial injection of saline solution (Gsf-control group, 10) or fluorescent dye solution (Gdye group, 30) followed by parotidectomy preserving the facial nerve, measuring the time for localization and facility of localization (LocTime and LFN). Nerve function was assessed using the Vibrissae Movements (PMV) and Eyelid Closure Motion (PFP) scores. RESULTS Nerve localization was faster in Gdye group, with 83% Easy LFN rate. The Gdye group presented with low nerve injury degree and better PMV and PFP scores, with high sensitivity and accuracy. CONCLUSIONS This experimental method of facial nerve fluorescence was effective for intraoperative nerve visualization, identification and preservation. The technique may be used in future facial nerve studies, translated to humans, contributing to the optimization of parotid surgery in the near future.
Descritores: Glândula Parótida/cirurgia
Carbocianinas/administração & dosagem
Nervo Facial/cirurgia
Corantes Fluorescentes/administração & dosagem
-Fatores de Tempo
Variações Dependentes do Observador
Sensibilidade e Especificidade
Ratos Wistar
Modelos Animais
Dissecação/métodos
Microinjeções/instrumentação
Microscopia de Polarização
Limites: Animais
Masculino
Tipo de Publ: Research Support, Non-U.S. Gov't
Responsável: BR1.1 - BIREME


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Texto completo SciELO Brasil
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Id: lil-741534
Autor: Miziara, Ivan; Chagury, Azis; Vargas, Camila; Freitas, Ludmila; Mahmoud, Ali.
Título: Therapeutic Options in Idiopathic Burning Mouth Syndrome: Literature Review
Fonte: Int. arch. otorhinolaryngol. (Impr.);19(1):86-89, Jan-Mar/2015.
Idioma: en.
Resumo: Introduction Burning mouth syndrome (BMS) is characterized by a burning sensation in the tongue, palate, lips, or gums of no well-defined etiology. The diagnosis and treatment for primary BMS are controversial. No specific laboratory tests or diagnostic criteria are well established, and the diagnosis is made by excluding all other possible disorders. Objective To review the literature on the main treatment options in idiopathic BMS and compare the best results of the main studies in 15 years. Data Synthesis We conducted a literature review on PubMed/MEDLINE, SciELO, and Cochrane-BIREME of work in the past 15 years, and only selected studies comparing different therapeutic options in idiopathic BMS, with preference for randomized and double-blind controlled studies. Final Comments Topical clonazepam showed good short-term results for the relief of pain, although this was not presented as a definitive cure. Similarly, α-lipoic acid showed good results, but there are few randomized controlled studies that showed the longterm results and complete remission of symptoms. On the other hand, cognitive therapy is reported as a good and lasting therapeutic option with the advantage of not having side effects, and it can be combined with pharmacologic therapy. .
Descritores: Diferenciação Celular/efeitos dos fármacos
Hidrogéis/farmacologia
Células-Tronco Pluripotentes/fisiologia
Nicho de Células-Tronco/efeitos dos fármacos
-Alginatos
Carbocianinas
Colágeno
Ácido Glucurônico
Ácidos Hexurônicos
Células-Tronco Pluripotentes/efeitos dos fármacos
Medicina Regenerativa/métodos
Análise Espectral
Limites: Humanos
Tipo de Publ: Research Support, Non-U.S. Gov't
Responsável: BR1.1 - BIREME


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Id: lil-383548
Autor: Chen, Jin Haw; Vasconcelos, Taisa Mourão; Velasco, Tonicarlo Rodrigues; Cukier, Arthur; Martins, Antonio Roberto; Leite, João Pereira.
Título: Reciprocal connections between subcortical nodular heterotopic tissue and adjacent normotopic cortex in humans: a carbocyanine study
Fonte: Arq. neuropsiquiatr;61(supl.1):15-18, set. 2003. ilus.
Idioma: en.
Descritores: Encefalopatias/fisiopatologia
Córtex Cerebral/fisiopatologia
Coristoma/fisiopatologia
Epilepsia do Lobo Temporal/fisiopatologia
Neurônios/fisiologia
-Encéfalo/fisiopatologia
Carbocianinas
Corantes
Vias Neurais
Limites: Humanos
Feminino
Criança
Tipo de Publ: Relatos de Casos
Responsável: BR1.1 - BIREME


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Id: lil-148315
Autor: Bravo, Hermes.
Título: Poda selectiva de las proyecciones comisurales del colículo superior de la rata durante el desarrollo posnatal / Selective pruning of commisural projections in the superior colliculus of the rat during posnatal development
Fonte: Rev. chil. anat;12(4):147-51, 1994. ilus.
Idioma: es.
Resumo: En el presente trabajo he estudiado los cambios que ocurren en proyecciones intercoliculares rata durante el desarrollo posnatal de la rata. El uso de la carbocianina DiI ha permitido marcar los axones comisurales del colículo superior. Durante el período postnatal temprano (P-1 a P-5), se observan proyecciones comisurales muy abundantes, que se distribuyen a gran parte del colículo superior contralateral. A partir del día 15 estas proyecciones se van reduciendo para adquirir, alrededor del día 30, el aspecto observado en el adulto. Existe, por lo tanto, un proceso de poda o eliminación selectiva de las proyecciones intercoliculares durante el desarrollo postnatal
Descritores: Colículos Superiores/ultraestrutura
-Axônios/ultraestrutura
Carbocianinas
Córtex Cerebral/ultraestrutura
Ratos/crescimento & desenvolvimento
Colículos Superiores/crescimento & desenvolvimento
Limites: Animais
Ratos
Responsável: CL1.1 - Biblioteca Central



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