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  1 / 19 LILACS  
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Id: biblio-1007336
Autor: Benites, Julio; Guerrero-Castilla, Angélica; Salas, Felipe; Martinez, José L; Jara-Aguilar, Rafael; Venegas-Casanova, Edmundo A; Suarez-Rebaza, Luz; Guerrero-Hurtado, Juana; Buc Calderon, Pedro.
Título: Chemical composition, in vitro cytotoxic and antioxidant activities of the essential oil of Peruvian Minthostachys mollis Griseb / Composición química, actividades citotóxicas y antioxidantes in vitro del aceite esencial de Minthostachys mollis Griseb peruano
Fonte: Bol. latinoam. Caribe plantas med. aromát;17(6):566-574, nov. 2018. tab, ilus.
Idioma: en.
Resumo: The composition of the essential oil obtained by hydrodistillation from Minthostachys mollis Griseb (Lamiaceae) aerial parts was determined by GC and GC/MS. Menthone (13.2%), pulegone (12.4%), cis-dihydrocarvone (9.8%) and carvacrol acetate (8.8%) were the main essential oil components. The cytotoxic activity of the essential oil was in vitro measured using the MTT colorimetric assay. IC50 values were calculated on healthy non-tumor cells (HEK-293) and three human cancer cell lines (T24, DU-145 and MCF-7). In such latter cells, the estimated values were around 0.2 mg/mL. In addition, the antioxidant activity was determined by interaction with the stable free radical 2,2"-diphenyl-1-picrylhydrazyl. The essential oil was almost devoid of antioxidant activity indicating that its anti-proliferative action relies on other unknown mechanism.

La composición del aceite esencial obtenido por hidrodestilación a partir de partes aéreas de Minthostachys mollis Griseb (Lamiaceae) se determinó mediante GC y GC/MS. Mentona (13.2%), pulegona (12.4%), junto con cis-dihidrocarvona (9.8%) y acetato de carvacrol (8.8%) fueron los principales componentes del aceite esencial. La actividad citotóxica del aceite esencial se midió in vitro utilizando el ensayo colorimétrico MTT tanto en células sanas no tumorales (HEK-293) como en tres líneas celulares de cáncer humano (T24, DU-145 y MCF-7). Los valores de IC50 calculados fueron de alrededor de 0.2 mg/mL. Además, se determinó la actividad antioxidante por su interacción con el radical libre 2,2"-difenil-1-picrilhidrazilo. El aceite esencial tiene baja actividad antioxidante, lo que indica que su acción antiproliferativa depende de otro mecanismo desconocido.
Descritores: Óleos Voláteis/farmacologia
Lamiaceae
Linhagem Celular Tumoral/efeitos dos fármacos
Antioxidantes/farmacologia
-Peru
Picratos
Terpenos/análise
Bioensaio
Compostos de Bifenilo
Calorimetria
Óleos Voláteis/química
Sobrevivência Celular/efeitos dos fármacos
Depuradores de Radicais Livres
Cromatografia Gasosa-Espectrometria de Massas
Antioxidantes/química
Responsável: CL1.1 - Biblioteca Central


  2 / 19 LILACS  
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Id: lil-795828
Autor: Mesa-Vanegas, Ana María; Zapata-Uribe, Sebastián; Arana, Luis Miguel; Zapata, Isabel Cristina; Monsalve, Zulma; Rojano, Benjamín.
Título: Actividad antioxidante de extractos de diferente polaridad de Ageratum conyzoides L / Antioxidant activity of different polarity extracts from Ageratum conyzoides L
Fonte: Bol. latinoam. Caribe plantas med. aromát;14(1):1-10, ene.2015. ilus, tab.
Idioma: es.
Resumo: The present study aimed to investigate the antioxidant activity of extracts of different polarity of the species Ageratum conyzoides L., evaluating by different spectrophotometric methods: ABTS•+, DPPH•, FRAP and ORAC. Extracts of A. conyzoides L., showed good antioxidant activity in the methodologies evaluated. The extract was the most active of ethyl acetate (ACExtA) which showed the best evaluated values techniques with higher power as determined by the assay values of TEAC ORAC = 494048.95 +/- 29695.80 uMol Trolox/100g sample. Measurements of antioxidant activity by different techniques offer advantages in terms of predicting the in vitro antioxidant capacity of this plant, it is also recommended to explore the structural characteristics of the compounds present in the ethyl acetate extract of the plant with to explore the potential benefits and possible mechanisms of action of new antioxidants...

El presente trabajo tuvo como objetivo investigar la actividad antioxidante de extractos de diferente polaridad de la especie Ageratum conyzoides L., mediante la evaluación por diferentes métodos espectrofotométricos: ABTS•+, DPPH•, FRAP y ORAC. Los extractos de A. conyzoides L., presentaron una buena actividad antioxidante en las metodologías evaluadas. El extracto más activo fue el de acetato de etilo (ACExtA), que presentó los mejores valores por las técnicas evaluadas con la mayor potencia determinada por el ensayo ORAC con valores de TEAC = 494048,95 +/- 29695,80 uMol Trolox/100g muestra. Las mediciones de la actividad antioxidante por diferentes técnicas, ofrecen ventajas en términos de la predicción de la capacidad antioxidante in vitro de esta planta, además se recomienda explorar las características estructurales de los compuestos presentes en el extracto de acetato de etilo de esta planta con el fin de investigar los beneficios potenciales y los mecanismos de acción de posibles nuevos antioxidantes...
Descritores: Ageratum/química
Antioxidantes/farmacologia
Extratos Vegetais/farmacologia
-Antioxidantes/química
Compostos de Bifenilo
Espécies Reativas de Oxigênio
Extratos Vegetais/química
Compostos Férricos
Oxirredução
Picratos
Limites: Seres Humanos
Responsável: CL1.1 - Biblioteca Central


  3 / 19 LILACS  
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Id: lil-786492
Autor: Martínez, Nelvy; Almaguer, Georgina; Vázquez-Alvarado, Patricia; Figueroa, Ana; Zúñiga, Clara; Hernández-Ceruelos, Alejandra.
Título: Análisis fitoquímico de Jatropha dioica y determinación de su efectoantioxidante y quimioprotector sobre el potencial genotóxico deciclofosfamida, daunorrubicina y metilmetanosulfonato evaluadomediante el ensayo cometa / Phytochemical analysis of Jatropha dioica and determination of its antioxidant and chemopreventive effect on the genotoxic potential of cyclophosphamide, daunorubicin and methyl methane-sulfonate evaluated by the comet assay
Fonte: Bol. latinoam. Caribe plantas med. aromát;13(5):437-457, sept.2014. ilus, tab, graf.
Idioma: es.
Resumo: Dragon ́s blood root (Jatropha dioica) underwent a phytochemical screening showing the presence of flavonoids and terpenes responsible for the antioxidant potential observed in DPPH model for the decoction, aqueous and methanolic extracts. The chemoprotective effect of the root decoction was evaluated in liver, kidney and bone marrow cells of mice using the comet assay. Mutagens were administered via IP: cyclophosphamide (CCF) 50 mg/kg, daunorubicin (DAU) 10 mg/kg, and metyl metanesulfonate (MMS) 40 mg/kg, were co-administered with three doses of decoction 3.72 ml/kg, 10.71 ml/kg, and 21.42 ml/kg orally. Animals were sacrificed at 3, 9, 15 and 21 h after inoculation. The chemoprotective effect decreased DNA breaks at 3 hours in all organs, and longer against CCF and DAU, this effect probably being related to the antioxidant capacity of the decoction.

La raíz de Sangre de Drago (Jatropha dioica) se sometió a un tamizaje fitoquímico destacando la presencia de flavonoides y terpenos, posibles responsables del efecto antioxidante observado en el modelo de DPPH para la decocción, extracto acuoso y metanólico de la raíz. El efecto quimioprotector de la decocción, se evaluó en células hepáticas, renales y de médula ósea de ratón, mediante el ensayo cometa. Los mutágenos administrados vía I.P.: ciclofosfamida (CCF) 50 mg/kg, daunorrubicina (DAU) 10 mg/kg y metilmetanosulfonato (MMS) 40 mg/kg, se co-administraron con tres dosis de decocción 3,72 ml/kg, 10,71 ml/kg y 21,42 ml/kg, vía oral. Los animales fueron sacrificados a las 3, 9, 15 y 21 h posteriores a la aplicación. El efecto quimioprotector disminuyó las rupturas del DNA a las 3 horas en todos los órganos con los tres mutágenos, y permaneció por más tiempo frente a CCF y DAU, dicho efecto está relacionado con la capacidad antioxidante de la decocción.
Descritores: Antioxidantes/farmacologia
Extratos Vegetais/farmacologia
Genotoxicidade/prevenção & controle
Jatropha/química
Substâncias Protetoras/farmacologia
-Compostos de Bifenilo
Ensaio Cometa
Ciclofosfamida/toxicidade
Daunorrubicina/toxicidade
Metanossulfonato de Metila/toxicidade
Picratos
Limites: Animais
Camundongos
Responsável: CL1.1 - Biblioteca Central


  4 / 19 LILACS  
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Texto completo SciELO Brasil
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Id: lil-767061
Autor: Mittal, A.; Tandon, S.; Singla, S.K.; Tandon, C..
Título: In vitro studies reveal antiurolithic effect of Terminalia arjuna using quantitative morphological information from computerized microscopy
Fonte: Int. braz. j. urol;41(5):935-944, Sept.-Oct. 2015. tab, graf.
Idioma: en.
Resumo: ABSTRACT Purpose: For most cases, urolithiasis is a condition where excessive oxalate is present in the urine. Many reports have documented free radical generation followed by hyperoxaluria as a consequence of which calcium oxalate (CaOx) deposition occurs in the kidney tissue. The present study is aimed to exam the antilithiatic potency of the aqueous extract (AE) of Terminalia arjuna (T. arjuna). Materials and Methods: The antilithiatic activity of Terminalia arjuna was investigated in vitro nucleation, aggregation and growth of the CaOx crystals as well as the morphology of CaOx crystals using the inbuilt software ‘Image-Pro Plus 7.0’ of Olympus upright microscope (BX53). Antioxidant activity of AE of Terminalia arjuna bark was also determined in vitro. Results: Terminalia arjuna extract exhibited a concentration dependent inhibition of nucleation and aggregation of CaOx crystals. The AE of Terminalia arjuna bark also inhibited the growth of CaOx crystals. At the same time, the AE also modified the morphology of CaOx crystals from hexagonal to spherical shape with increasing concentrations of AE and reduced the dimensions such as area, perimeter, length and width of CaOx crystals in a dose dependent manner. Also, the Terminalia arjuna AE scavenged the DPPH (2, 2-diphenyl-1-picrylhydrazyl) radicals with an IC50 at 13.1µg/mL. Conclusions: The study suggests that Terminalia arjuna bark has the potential to scavenge DPPH radicals and inhibit CaOx crystallization in vitro. In the light of these studies, Terminalia arjuna can be regarded as a promising candidate from natural plant sources of antilithiatic and antioxidant activity with high value.
Descritores: Antioxidantes/farmacologia
Oxalato de Cálcio/química
Extratos Vegetais/farmacologia
Terminalia/química
Cálculos Urinários/prevenção & controle
-Análise de Variância
Compostos de Bifenilo/química
Cristalização
Depuradores de Radicais Livres/farmacologia
Fitoterapia
Picratos/química
Valores de Referência
Reprodutibilidade dos Testes
Cálculos Urinários/química
Tipo de Publ: Estudos de Avaliação
Responsável: BR1.1 - BIREME


  5 / 19 LILACS  
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Texto completo SciELO Brasil
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Id: lil-755829
Autor: Tajalli, Faezeh; Malekzadeh, Khalil; Soltanian, Hadi; Janpoor, Javad; Rezaeian, Sharareh; Pourianfar, Hamid R..
Título: Antioxidant capacity of several Iranian, wild and cultivated strains of the button mushroom
Fonte: Braz. j. microbiol;46(3):769-776, July-Sept. 2015. tab, ilus.
Idioma: en.
Resumo:

The white button mushroom, Agaricus bisporus, is the most commonly grown mushroom in Iran; however, there is a significant shortage of research on its antioxidant activity and other medicinal properties. The aim of this study was to evaluate antioxidant capacity of the methanolic extracts from four cultivated strains and four Internal Transcribed Spacer (ITS)-identified, Iranian wild isolates of A. bisporus. Evaluations were made for total phenols, flavonoids and anthocyanins, and 2, 2-diphenyl-1-picrylhydrazyl (DPPH) scavenging activity. Overall, results showed that all the wild isolates exhibited significantly lower DPPH-derived EC50, compared to the cultivated strains (p < 0.05). A relatively high relationship was observed between total phenols and flavonoids or anthocyanins (r2 > 0.60). However, these constituents could not statistically differentiate the group of wild samples from the cultivated ones, and there was low correlation with the DPPH-derived EC50s (r2 < 0.40). In conclusion, comparisons showed that wild isolate 4 and cultivated strains A15 and H1 had higher antioxidant capacity than the others (p < 0.05). This result identifies these mushrooms as good candidates for further investigation.

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Descritores: Agaricus/metabolismo
Antocianinas/metabolismo
Antioxidantes/metabolismo
Compostos de Bifenilo/metabolismo
Flavonoides/metabolismo
Fenóis/metabolismo
Picratos/metabolismo
-Agaricus/genética
DNA Intergênico/genética
Irã (Geográfico)
Oxirredução
Espécies Reativas de Oxigênio/metabolismo
Limites: Seres Humanos
Tipo de Publ: Research Support, Non-U.S. Gov't
Responsável: BR1.1 - BIREME


  6 / 19 LILACS  
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Texto completo SciELO Chile
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Id: lil-734617
Autor: Jantakee, Kanyaluck; Tragoolpua, Yingmanee.
Título: Activities of different types of Thai honey on pathogenic bacteria causing skin diseases, tyrosinase enzyme and generating free radicals
Fonte: Biol. Res;48:1-11, 2015. graf, tab.
Idioma: en.
Projeto: Chiang Mai University. Faculty of Science; . The Thailand Research Fund-Research and Researchers for Industry; . Bee Products Industry Co.
Resumo: BACKGROUND: Honey is a natural product obtained from the nectar that is collected from flowers by bees. It has several properties, including those of being food and supplementary diet, and it can be used in cosmetic products. Honey imparts pharmaceutical properties since it has antibacterial and antioxidant activities. The antibacterial and antioxidant activities of Thai honey were investigated in this study. RESULTS: The honey from longan flower (source No. 1) gave the highest activity on MRSA when compared to the other types of honey, with a minimum inhibitory concentration of 12.5% (v/v) and minimum bactericidal concentration of 25% (v/v). Moreover, it was found that MRSA isolate 49 and S. aureus were completely inhibited by the 50% (v/v) longan honey (source No. 1) at 8 and 20 hours of treatment, respectively. Furthermore, it was observed that the honey from coffee pollen (source No. 4) showed the highest phenolic and flavonoid compounds by 734.76 mg gallic/kg of honey and 178.31 mg quercetin/kg of honey, respectively. The antioxidant activity of the honey obtained from coffee pollen was also found to be the highest, when investigated using FRAP and DPPH assay, with 1781.77 mg FeSO4•7H2O/kg of honey and 86.20 mg gallic/kg of honey, respectively. Additionally, inhibition of tyrosinase enzyme was found that honey from coffee flower showed highest inhibition by 63.46%. CONCLUSIONS: Honey demonstrates tremendous potential as a useful source that provides anti-free radicals, anti-tyrosinase and anti-bacterial activity against pathogenic bacteria causing skin diseases.
Descritores: Apiterapia
Flavonoides/análise
Mel/análise
Monofenol Mono-Oxigenase
Staphylococcus aureus Resistente à Meticilina/efeitos dos fármacos
Fenóis/análise
Pólen/química
-Antibacterianos/farmacologia
Antioxidantes/farmacologia
Compostos de Bifenilo
Café/química
Recuperação de Fluorescência Após Fotodegradação
Flores/química
Radicais Livres/análise
Mel/classificação
Testes de Sensibilidade Microbiana
Monofenol Mono-Oxigenase/antagonistas & inibidores
Monofenol Mono-Oxigenase/efeitos dos fármacos
Picratos
Pólen/classificação
Dermatopatias/microbiologia
Dermatopatias/terapia
Preparações Clareadoras de Pele/farmacologia
Tailândia
Fatores de Tempo
Viscosidade
Tipo de Publ: Research Support, Non-U.S. Gov't
Responsável: CL1.1 - Biblioteca Central


  7 / 19 LILACS  
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Id: lil-726590
Autor: Mex-Álvarez, RMJ; Bolívar-Fernández, NJ; Garma-Quen, PM; Tut-Heredia, JA; Romero-Guillén, KI.
Título: Actividad antioxidante de cinco variedades de maíz cultivadas en Campeche, México / Activity antioxidant of maize extracts from Campeche, Mexico
Fonte: Bol. latinoam. Caribe plantas med. aromát;12(6):558-571, nov. 2013. ilus, graf.
Idioma: es.
Resumo: We studied the antioxidant capacity of five varieties of corn grown in Hopelchén, Mexico by the techniques of DPPH, DMPD, oxidation rate, ferric ion reduction and peroxide, the purple variety had the highest antioxidant activity except in test DMPD the red variety which had a better capacity to reduce, in general, the white varieties (native and hybrid) showed similar activity and yellow corn had the lowest activity of all. It also determines the concentration of phenolic compounds and anthocyanins that are present in the corn kernels in a range of 3.39 to 1558 mg of polyphenols and 0,847 to 410 mg of anthocyanins per 100 g of flour. The content of antioxidants in maize varieties can consider it as a functional food by providing exogenous antioxidants to consumers with a consequent protective effects.

Se estudió la capacidad antioxidante de cinco variedades de maíz cultivadas en Hopelchén, México por las técnicas de DPPH (2,2-difenil-1-pricrilhidrazilo), DMPD (N, N,- dimetil-p-fenilendiamina), índice de oxidación, reducción del ion férrico y del peróxido. La variedad morada presentó la mayor actividad antioxidante; excepto en el ensayo de DMPD, en el cual la variedad roja tuvo una mejor capacidad reductora. En general, las variedades blancas (criolla e híbrida) mostraron una actividad similar y, la variedad amarillo tuvo la menor actividad de todas. También se determinó la concentración de compuestos fenólicos y antociánicos que están presentes en las diferentes variedades de maíz en un rango de 3.39 a 1558 mg de polifenoles y de 0.847 a 410 mg de antocianidinas por cada 100 g de harina. El contenido de antioxidantes en las variedades de maíz permite considerarlo como alimento funcional al aportar antioxidantes exógenos a su consumidor con sus consecuentes efectos protectores.
Descritores: Antioxidantes/química
Extratos Vegetais/química
Zea mays/química
-Antioxidantes/farmacologia
Antocianinas/análise
Compostos de Bifenilo
Extratos Vegetais/farmacologia
México
Picratos
Polifenóis/análise
Responsável: CL1.1 - Biblioteca Central


  8 / 19 LILACS  
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Id: lil-723580
Autor: Campagna, María N; Martínez, María L; Broussalis, Adriana; Gattuso, Martha.
Título: Actividad antioxidante, análisis fitoquímico y micrografía analítica de hojas de Castela tweedii (Simaroubaceae) / Antioxidant activity, phytochemical analisys and micrographic characterization of Castela tweedii (Simaroubaceae) leaves
Fonte: Bol. latinoam. Caribe plantas med. aromát;11(6):498-509, nov. 2012. ilus, graf.
Idioma: es.
Resumo: Castela tweedii is a small tree belonging to Simaroubaceae family. Infusions of its leaves are used in folk medicine to treat gastrointestinal disorders and diarrhea. In this work, we evaluated the antioxidant activity of ethanol and dicloromethane leaves extracts against DPPH radical (2,2-difenilpicrilhidrazil) in order to justify, at least in part, its popular use. Ethanol extract showed scavenging activity, with an IC50=0.1288 mg/mL. Responsible compounds for these activity were tannins, flavonoids and phenylcarboxilic acids, among them we identified rutine and chlorogenic acid. Microscopic and histochemical analysis of leaves was carry out to developed useful characterizations that will allow a future identification and authentication of raw material: such as, the presence of mucilaginous hypodermis, leaf of dorsiventral structure, 1 to 2 rows of empalisade parenchyma with tannin deposits, anomocytic stomata in low epidermis and simple, unicellular trichomes in both epidermis.

Castela tweedii es un árbol de bajo porte perteneciente a la Familia Simaroubaceae, las infusiones de sus hojas son utilizadas en la medicina popular Argentina para el tratamiento de desordenes gastrointestinales y diarreas. Con el objetivo de fundamentar el uso popular de esta especie se evaluó la actividad antioxidante de los extractos etanólicos y diclorometánicos de forma cuantitativa y cualitativa frente al radical 2,2-difenilpicrilhidrazilo (DPPH); el extracto etanólico demostró actividad obteniéndose una CI50= 0,1288 mg/mL. El análisis fitoquímico mostró que los compuestos responsables de esta actividad fueron taninos, flavonoides y ácidos fenilcarboxílicos, entre ellos se identificó rutina y ácido clorogénico. Además se realizó el estudio morfoanatómico e histoquímico de las hojas que aportó datos de valor diagnostico para el control de calidad de la droga vegetal: presencia de una hipodermis mucilaginosa, estructura dorsiventral con una a dos hileras de parénquima en empalizada conteniendo taninos, estomas anomocíticos solo en la epidermis abaxial y tricomas simples unicelulares en ambas epidermis.
Descritores: Antioxidantes/farmacologia
Extratos Vegetais/farmacologia
Simaroubaceae/química
-Compostos de Bifenilo
Cromatografia
Etanol
Histocitoquímica
Folhas de Planta/química
Picratos
Simaroubaceae/anatomia & histologia
Responsável: CL1.1 - Biblioteca Central


  9 / 19 LILACS  
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Id: lil-723576
Autor: Martínez, M. Laura; Travaini, M. Lucía; Rodríguez, M. Victoria; Orellano, Elena; Nocito, Isabel; Serra, Esteban; Gattuso, Martha; Cortadi, Adriana.
Título: Tripanocide and antibacterial activity ofAlvaradoa subovata Cronquist extracts / Actividad tripanocida y antibacteriana de extractos de Alvaradoa subovata Cronquist
Fonte: Bol. latinoam. Caribe plantas med. aromát;12(3):302-312, mayo 2013. ilus.
Idioma: en.
Projeto: Agencia de Promociones Científicas y Tecnológicas de la Argentina.
Resumo: We studied antioxidant, antibacterial and tripanocide activities of Alvaradoa subovata extracts. The ethanolic extracts showed the greatest DPPH radical scavenging capacity, especially that of bark with an IC50 = 4.7 +/- 0.18 ug/mL. Wood dichloromethane extract displayed growth inhibition of the phytopathogenic bacteria Xanthomona axonopodis in the disk diffusion assay and showed a MIC value of 100 ug/ml. It also showed growth inhibition of Trypanosoma cruzi (IC50 = 0.063 +/- 0.003 mg/mL). A fraction of this extract, which has emodin as the main component, showed tripanocide activity (60 percent of growth inhibition at 100 ug/mL). The main compounds in wood dichloromethane extract were anthraquinones, identified as chrysophanol and emodin, and coumarins, of which scopoletin was identified. These three compound s could serve as analytical markers of the extract. The results of this study show that wood extract of A. subovata constitute a source of bioactive compounds such as antiparasitic and pesticides agents.

En el presente trabajo se estudió la actividad antioxidante, antibacteriana y tripanocida de extractos de Alvaradoa subovata. La mayor actividad depuradora de radicales libres se observó en el extracto etanólico de corteza (CI50 = 4.7 +/- 0.18 ug/mL). El extracto en diclorometano de madera inhibió el crecimiento de la bacteria fitopatógena Xanthomona axonopodis con una CIM = 100 ug/mL. El mismo extracto mostró inhibición del crecimiento de Trypanosoma cruzi (CI50 = 0.063 +/- 0.003 mg/mL). Una fracción de este extracto (100 ug/mL), cuyo componente mayoritario es emodina, inhibió en un 60 por ciento el crecimiento del parásito. Los compuestos mayoritarios detectados en el extracto de madera fueron antraquinonas, entre las cuales se identificaron emodina y crisofanol, y la cumarina escopoletina. Estos tres compuestos podrían servir como marcadores analíticos del extracto. Los resultados de este trabajo muestran que los extractos de A. subovata constituyen una fuente de compuestos bioactivos con potencial como antiparasitarios y plaguicidas.
Descritores: Antibacterianos/farmacologia
Extratos Vegetais/farmacologia
Simaroubaceae/química
Tripanossomicidas/farmacologia
-Antioxidantes/farmacologia
Compostos de Bifenilo/química
Depuradores de Radicais Livres
Testes de Sensibilidade Microbiana
Picratos/química
Xanthomonas
Responsável: CL1.1 - Biblioteca Central


  10 / 19 LILACS  
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Id: lil-723572
Autor: Montenegro, Gloria; Santander, Francisca; Jara, Claudia; Nuñez, Gabriel; Fredes, Carolina.
Título: Actividad antioxidante y antimicrobiana de mieles monoflorales de plantas nativas chilenas / Antioxidant and antimicrobial activity of unifloral honeys of plants native to Chile
Fonte: Bol. latinoam. Caribe plantas med. aromát;12(3):257-268, mayo 2013. mapas, tab.
Idioma: es.
Projeto: FONDECYT.
Resumo: Chile has a great diversity of endemic and native species which gives floral origin to honey. Due the diversity of unifloral and multifloral honey previously identified it would be necessary to have information about the antioxidant content and biological activity. The objective of this study was to determine total phenols, antioxidant activity (DPPH and FRAP methods) and biological activity of unifloral honeys of native plants from Chile. For this purpose 59 beehoneys of different geographical origin were analyzed by melisopallinological method to determine the pollen present. Antimicrobial activity was tested against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus and Streptococcus pyogenes determining minimal bactericidal concentration (MBC). Results indicate that Chilean native honeys showed significant differences in their antioxidant as well as biological activity, which depends on the botanical and geographical origin, and it can be associated with polyphenol content.

Chile presenta una gran diversidad de especies vegetales endémicas y nativas que pueden dar origen a mieles producidas por Apis mellifera. En base a la diversidad de mieles poliflorales y monoflorales que han sido identificadas anteriormente en Chile, se propuso estudiar la actividad antioxidante y biológica para controlar el crecimiento de microorganismos patógenos. El objetivo de este estudio fue determinar el contenido de fenoles totales, actividad antioxidante (Métodos de FRAP y DPPH) y la actividad antibacteriana de mieles monoflorales de plantas nativas chilenas. Se utilizaron 59 mieles de diferente origen geográfico para determinar su origen botánico, mediante análisis melisopalinológico. La actividad antibactariana se evaluó contra Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus y Streptococcus pyogenes, determinando la concentración mínima bactericida (CMB). Los resultados indicaron que las mieles nativas de Chile muestran diferencias significativas tanto en la actividad antioxidante como en la actividad contra patógenos, la que depende del origen botánico y geográfico, pudiendo estar asociada al contenido de polifenoles.
Descritores: Antibacterianos/farmacologia
Antioxidantes/farmacologia
Mel
Plantas Medicinais/química
-Compostos de Bifenilo
Chile
Recuperação de Fluorescência Após Fotodegradação
Picratos
Responsável: CL1.1 - Biblioteca Central



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