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Pesquisa : D03.066.515.292 [Categoria DeCS]
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Id: lil-714001
Autor: Goulart-Cruz, Fernando Luíz; Brigolini de Faria, Júlio César; Carene-Cruz, Gustavo; Guevara-Canales, Janet Ofelia; Morales-Vadillo, Rafael; Pereira-Leite, Fabíola Pessoa.
Título: Efectos bucales de la nuez de betel / Oral effects of the betel nut
Fonte: Kiru;9(2):167-170, jul.-dic. 2012. ilus.
Idioma: es.
Resumo: La nuez de betel o nuez de areca es una semilla de la palmetra de betel (areca catechu), una de las plantas más polulares del mundo. Diversos pueblos asiáticos, por influencias culturales, tienen la costumbre de masticar la semilla de esta especie vegetal. Entre sus principios activos, la arecaina y la arecolina, son alcaloides comparables a la nicotina en los efectos nerviosos estimulantes. La sustancia activadora causa un relajamiento agradable en la boca, sensación que se propaga al sistema nervioso central. Sin embargo, masticar regularmente la nuez de betel, tiñe la saliva de rojo vivo y ennegrece los dientes, siendo extremadamente perjudicial para la salud oral, causando la pérdida precoz de dientes. A pesar de sus efectos maléficos, existe la dificultad de erradicar el hábito, debido a su carácter cultural, donde las manchas son motivo de orgullo. La agencia internacional de investigación del cáncer (IARC) clasifica a la nuez de betel como un cancerígeno, existiendo numerosos estudios que relacionen la costumbre con neoplasias bucales. El estudio tiene por finalidad realizar un análisis crítico sobre el uso de esta sustancia, buscando informar a la comunidad para prevenir sus efectos maléficos.

The betel nut or areca nut is the seed of the palm tree of bétele (areca catechu), one of the most popular plants of the world. Asians, by cultural influence, have the custom of chew the seed of this sort of vegetable. Between its active principles: arecaine and arecoline, they are alkaloids comparable to the nicotine in the neural stimulation effects. The active substance causes a pleasant relaxion sensation in the mouth, sensation that is extended to the central nervous system. However, chewing regularly betel nut dryes of red the saliva and blackens the teeth being extremely harmful to the mouth health causing early the loss of the teeth. Despite of the harmful effects, the difficulty to eliminate this habit is due to its deep cultural character. Chewing bétel nuts and have the teeth stained it's a motive of proud. The International Agency of Research of the Cancer (IARC) classifies the bétel nut as carcinogenic acquaintance, and the literature have many studies that relate this custom with the oral cancer. The study has as goal to do a critical analysis of the utilization of this substance, searching to inform to the community their bad effects.
Descritores: Areca
Arecolina
Neoplasias Bucais
Perda de Dente
Tipo de Publ: Revisão
Responsável: PE264.3 - Biblioteca


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Id: lil-440715
Autor: Perez, Alicia; Costa, Maria T; Cantoni, Gustavo; Mancini, Sergio; Mercapide, Carlos; Herrero, Eduardo; Volpe, Marcela; Araya, Daniel; Talmon, Gabriel; Chiosso, Carlos; Vázquez, Gabriela; Del Carpio, Mario; Santillan, Graciela; Larrieu, Edmundo.
Título: Vigilancia epidemiologica de la equinococcosis quistica en perros, establecimientos ganaderos y poblaciones humanas en la Provincia de Rio Negro / Vigilancia epidemiologica de la equinococcosis quistica en perros, establecimientos ganaderos y poblaciones humanas en la Provincia de Rio Negro
Fonte: Medicina (B.Aires);66(3):193-200, 2006. graf, tab.
Idioma: es.
Resumo: La vigilancia de la equinococcosis quística para detectar infestación por Echinococcus granulosus en la Provincia de Río Negro en el período 1980-2002 fue efectuada en el hombre mediante encuestas serológicas y ultrasonográficas en población joven, y en el perro por el test de arecolina. Dadas las limitaciones de esta técnica, se planteó suplantarla por el complejo copro ELISA Western Blot en heces caninas recolectadas del suelo. El objetivo del presente trabajo fue comparar las ventajas y limitaciones de las dos técnicas para medir la prevalencia de la infección en el perro, y evaluar la prevalencia actual de la infección en el hombre y en el perro. Elárea de trabajo comprendió 7 Departamentos endémicos con Programas de desparasitación canina sistemática (Area Programa) y 4 Departamentos no endémicos como Area Testigo. El test de arecolina se aplicó en los perros, con concurrencia voluntaria de sus propietarios (muestreo no aleatorizado). Las muestras para detección de coproantígenosfueron obtenidas de establecimientos ganaderos seleccionados en forma aleatorizada. En el hombre se determinó la prevalencia mediante tamizajes ultrasonográficos en escolares de 6 a 14 años y la incidencia por medio del sistema oficial de notificación de casos sintomáticos. Se dosificaron con arecolina 416 perros resultando 19 (5.2%) positivos en el Area Programa y ninguno positivo en el Area Testigo. Para la detección de coproantígenos se obtuvieron 748 muestras de materia fecal de 271 establecimientos ganaderos, resultando 37 muestras y 32 establecimientos (13.6%) positivos en el Area Programa y 4 muestras y 4 establecimientos (11.4%, IC: 0.3-32.3) positivos en el Área Testigo. En el Area Programa se efectuaron 7421 ecografías abdominales a escolares, detectándose 40 (0.5%) casos conimágenes compatibles con hidatidosis, mientras en el área testigo se efectuaron 1732 ecografías con 9 (0.5%) casos positivos...

The surveillance of infection for Echinococcus granulosus in the Provinceof Rio Negro during 1980-2002 included serological and ultrasonographic screening in humans and arecoline testin dogs. In lieu of the limitations of the arecoline test the proposal was to supplant that test for the copro Elisacopro/Western Blot complex applied to feces collected from the environment. The objective was to compare the pros and cons of the two tests and to evaluate the human and the canine infection prevalence. The working area encompassed 7 Departments with systematic canine parasiticide activities (Program Area) and 4 Departments, not endemic, as Control Area. The arecoline test was applied to the dogs in assembled groups with the voluntary participation of their owners (not randomized sampling). Samples for the detection of coproantigens were obtained from sheep farms selected at random and analyzed by the complex copro-LISA /Western Blot. Prevalence inman was determined by screening the school population (6 to 14 years old) by ultrasound, and by means of the compulsory notification of cases from the official system. Dogs (416) were tested with arecoline, 365 of whichbelonged to the Program Area. Of these 19 (5.2%) resulted positive, while none of 51 dogs from the Control Areawere positive. Samples (748) of feces were tested to detect coproantigens, obtaining 37 positive samples withinthe Program Area and 4 within the Control Area. Farms (271) from the livestock estate unit were evaluated, outof which 236 belonged to the Program Area, gave 32 (13.6%) positive results, while 4 (11.4%) of 35 from theControl Area resulted positive. Sonography tests (7421) were done in the Program Area detecting 40 (0.5%)carriers, while in the Control Area, over 1732 tests, 9 (0.5%) resulted positive...
Descritores: Arecolina
Doenças do Cão/epidemiologia
Equinococose/veterinária
Echinococcus granulosus/isolamento & purificação
Doenças dos Ovinos/epidemiologia
Zoonoses/epidemiologia
-Argentina/epidemiologia
Western Blotting
Doenças do Cão/parasitologia
Ensaio de Imunoadsorção Enzimática
Equinococose/diagnóstico
Equinococose/epidemiologia
Fezes/parasitologia
Incidência
Contagem de Ovos de Parasitas
Vigilância da População
Prevalência
Ovinos
Doenças dos Ovinos/parasitologia
Limites: Humanos
Animais
Criança
Adolescente
Cães
Responsável: BR1.1 - BIREME


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Id: lil-266055
Autor: Torres, Argenis; Dávila, Diego F; Gottberg, Carlos F; Donis, Jose H; Arata de Bellabarba, Gabriela; Ramoni-Perazzi, Paolo.
Título: Heart rate responses to a muscarinic agonist in rats with experimentally induced acute and subacute chagasic myocarditis
Fonte: Rev. Inst. Med. Trop. Säo Paulo;42(4):219-24, July-Aug. 2000. tab, graf.
Idioma: en.
Resumo: We administered arecoline to rats, with experimentally induced chagasic myocarditis, in order to study the sinus node sensitivity to a muscarinic agonist. Sixteen month old rats were inoculated with 200,000 T. cruzi parasites ("Y" strain). Between days 18 and 21 (acute stage), 8 infected rats and 8 age-matched controls received intravenous arecoline as a bolus injection at the following doses: 5.0, 10.0, 20.0, 40.0, and 80.0 mug/kg. Heart rate was recorded before, during and after each dose of arecoline. The remaining 8 infected animals and 8 controls were subjected to the same experimental procedure during the subacute stage, i.e., days 60 to 70 after inoculation. The baseline heart rate, of the animals studied during the acute stage (349 Ý 68 bpm, mean Ý SD), was higher than that of the controls (250 Ý 50 bpm, p < 0.005). The heart rate changes were expressed as percentage changes over baseline values. A dose-response curve was constructed for each group of animals. Log scales were used to plot the systematically doubled doses of arecoline and the induced-heart rate changes. The slope of the regression line for the acutely infected animals (r = - 0.99, b =1.78) was not different from that for the control animals (r = - 0.97, b = 1.61). The infected animals studied during the subacute stage (r = - 0.99, b = 1.81) were also not different from the age-matched controls (r = - 0.99, b = 1.26, NS). Consequently, our results show no pharmacological evidence of postjunctional hypersensitivity to the muscarinic agonist arecoline. Therefore, these results indirectly suggest that the postganglionic parasympathetic innervation, of the sinus node of rats with autopsy proved chagasic myocarditis, is not irreversibly damaged by Trypanosoma cruzi.
Descritores: Arecolina/farmacologia
Cardiomiopatia Chagásica/metabolismo
Frequência Cardíaca/efeitos dos fármacos
Agonistas Muscarínicos/farmacologia
Nó Sinoatrial/efeitos dos fármacos
-Doença Aguda
Sistema Nervoso Parassimpático/efeitos dos fármacos
Sistema Nervoso Parassimpático/parasitologia
Ratos Wistar
Nó Sinoatrial/inervação
Limites: Animais
Ratos
Responsável: BR1.1 - BIREME


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Id: lil-189297
Autor: Larrieu, Edmundo Juan; Lamberti, Roberto; Casaza, Juan; Alvarez, Timoteo; Fonts, Carlos; Cavagion, Laura; Calvo, Claudio; Gino, Lilia.
Título: Hidatidosis/equinococosis en el área de General Acha, provincia de La Pampa de Argentina / Hydatidosis/echinococosis in General Acha area, La Pampa province, Argentina
Fonte: Bol. chil. parasitol;51(3/4):95-7, jul.-dic. 1996.
Idioma: es.
Resumo: Hydatidosis situation in the General Acha area (La Pampa province) is described herein. The work comprises a retrospective compilacion of new hydatidosis in human population, and investigation on dog echinococosis granulosus infection prevalence carried out on the basis of arecoline bromhydrate application. Sicteen human cases were detected during 1994 (incidence rate: 26,7/100,000) founding a serological prevalence of 1,3 percent. Studies on dog echinococosis have shown a prevalence rate of 2,3 percent. The epidemiological situation of hydatidosis is analyzed by comparison with values from other endemic areas. These results suggest the necessity of completing surveys in the whole provincial territory, and the implementation of educational and sanitary measures aimed to controlling this zoonosis.
Descritores: Cães/parasitologia
Equinococose/epidemiologia
Zoonoses/epidemiologia
-Arecolina/administração & dosagem
Argentina/epidemiologia
Reservatórios de Doenças
Equinococose/transmissão
Técnicas Imunoenzimáticas
Prevalência
Estudos Retrospectivos
Zona Rural
População Rural
Estudos Soroepidemiológicos
Área Urbana
Limites: Humanos
Animais
Masculino
Feminino
Adolescente
Adulto
Cães
Responsável: CL1.1 - Biblioteca Central



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