Base de dados : LILACS
Pesquisa : D12.644.276.860.381.500 [Categoria DeCS]
Referências encontradas : 3 [refinar]
Mostrando: 1 .. 3   no formato [Detalhado]

página 1 de 1

  1 / 3 LILACS  
              next record last record
seleciona
para imprimir
Fotocópia
Texto completo SciELO Brasil
Texto completo
Id: biblio-1039188
Autor: Cordeiro, Cynthia Azeredo; Vieira, Erica Leandro Marciano; Rocha, Natália Pessoa; Castro, Vinicius Monteiro; Oréfice, Juliana Lambert; Barichello, Tatiana; Costa, Rogerio Alves; Oréfice, Fernando; Young, Lucy; Teixeira, Antonio Lucio.
Título: Serum levels of neurotrophic factors in active toxoplasmic retinochoroiditis
Fonte: Braz. j. infect. dis;21(2):176-179, Mar.-Apr. 2017. graf.
Idioma: en.
Resumo: Abstract Toxoplasmic retinochoroiditis (TR) is the most common identifiable cause of posterior uveitis in Brazil. Response to treatment and clinical presentation may vary significantly. We assessed serum levels of brain-derived neurotrophic factor (BDNF), glial cell line-derived neurotrophic factor (GDNF), nerve growth factor (NGF), neurotrophin (NT)-3, and NT-4/5 in patients with active TR, before and after TR treatment. Methods: Twenty patients with active lesion and 15 healthy controls were enrolled in the study. Serum concentration of neurotrophic factors was determined by enzyme-linked immunosorbent assay. Results: BDNF levels were significantly higher in patients before treatment when compared with controls (p = 0.0015). There was no significant difference in pro-BDNF, NGF, GDNF, NT-3, and NT-4/5 levels between TR patients and controls. Treatment did not affect the levels of these factors. Conclusion: BDNF may be released in the context of the active TR inflammatory response.
Descritores: Biomarcadores/sangue
Toxoplasmose Ocular/sangue
Coriorretinite/sangue
-Ensaio de Imunoadsorção Enzimática
Estudos de Casos e Controles
Coriorretinite/parasitologia
Fator Neurotrófico Derivado do Encéfalo/sangue
Fator de Crescimento Neural/sangue
Neurotrofina 3/sangue
Fator Neurotrófico Derivado de Linhagem de Célula Glial/sangue
Fatores de Crescimento Neural/sangue
Limites: Humanos
Masculino
Feminino
Adulto
Responsável: BR1.1 - BIREME


  2 / 3 LILACS  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo SciELO Brasil
Texto completo
Id: biblio-959258
Autor: da Silva, Sally K; Wiener, Carolina; Ghisleni, Gabriele; Oses, Jean P; Jansen, Karen; Molina, Mariane L; Silva, Ricardo; Souza, Luciano D.
Título: Effects of cognitive-behavioral therapy on neurotrophic factors in patients with major depressive disorder
Fonte: Rev. bras. psiquiatr;40(4):361-366, Oct.-Dec. 2018. tab, graf.
Idioma: en.
Resumo: Objective: To correlate neurotrophic factors - brain-derived neurotrophic factor (BDNF), glial cell line-derived neurotrophic factor (GDNF), and beta-nerve growth factor (beta-NGF) - and severity of depressive symptoms in patients diagnosed with major depressive disorder (MDD) undergoing cognitive-behavioral therapy (CBT). Methods: In this quasi-experimental study, participants were selected by convenience and received 16 sessions of CBT. The outcomes of interest were severity of depressive symptoms and changes in neurotrophic factor levels after CBT. The differences between variables before and after treatment (deltas) were analyzed. Results: Patients had significant changes in symptom severity after treatment. No significant associations were found between Beck Depression Inventory II (BDI-II) scores and any independent variable. No correlations were observed between BDNF or GDNF levels and BDI scores before or after treatment, although there was a trend toward significant differences in beta-NGF levels. Conclusion: BDNF, beta-NGF, and GDNF were not influenced by the effects of CBT on depressive symptoms.
Descritores: Terapia Cognitivo-Comportamental/métodos
Fator Neurotrófico Derivado do Encéfalo/sangue
Fator de Crescimento Neural/sangue
Transtorno Depressivo Maior/sangue
Fator Neurotrófico Derivado de Linhagem de Célula Glial/sangue
-Escalas de Graduação Psiquiátrica
Fatores Socioeconômicos
Índice de Gravidade de Doença
Transtorno Depressivo Maior/diagnóstico
Transtorno Depressivo Maior/psicologia
Ensaios Clínicos Controlados não Aleatórios como Assunto
Fatores de Crescimento Neural/sangue
Limites: Humanos
Masculino
Feminino
Adulto
Pessoa de Meia-Idade
Adulto Jovem
Responsável: BR1.1 - BIREME


  3 / 3 LILACS  
              first record previous record
seleciona
para imprimir
Fotocópia
Texto completo SciELO Brasil
Texto completo
Id: biblio-888076
Autor: Bräunig, P; Glanzner, W. G; Rissi, V. B; Gonçalves, P. B. D.
Título: The differentiation potential of adipose tissue-derived mesenchymal stem cells into cell lineage related to male germ cells / Potencial de diferenciação de células-tronco mesenquimais derivadas do tecido adiposo em células da linhagem germinativa masculina
Fonte: Arq. bras. med. vet. zootec. (Online);70(1):160-168, Jan.-Feb. 2018. tab, graf.
Idioma: en.
Resumo: The adipose tissue is a reliable source of Mesenchymal stem cells (MSCs) showing a higher plasticity and transdifferentiation potential into multilineage cells. In the present study, adipose tissue-derived mesenchymal stem cells (AT-MSCs) were isolated from mice omentum and epididymis fat depots. The AT-MSCs were initially compared based on stem cell surface markers and on the mesodermal trilineage differentiation potential. Additionally, AT-MSCs, from both sources, were cultured with differentiation media containing retinoic acid (RA) and/or testicular cell-conditioned medium (TCC). The AT-MSCs expressed mesenchymal surface markers and differentiated into adipogenic, chondrogenic and osteogenic lineages. Only omentum-derived AT-MSCs expressed one important gene marker related to male germ cell lineages, after the differentiation treatment with RA. These findings reaffirm the importance of adipose tissue as a source of multipotent stromal-stem cells, as well as, MSCs source regarding differentiation purpose.(AU)

O tecido adiposo é uma fonte apropriada de células-tronco mesenquimais (MSCs), as quais demonstram ampla plasticidade com capacidade de transdiferenciar em diversas linhagens. No presente estudo, as células-tronco mesenquimais derivadas do tecido adiposo (AT-MSC) foram isoladas de tecido adiposo localizado nas regiões próximas ao omento e testículos de camundongos. Primeiramente, as AT-MSCs foram comparadas com base na expressão de marcadores antigênicos de superfície e no potencial de diferenciação nas três linhagens mesodérmicas. Além disso, AT-MSC, de ambas as fontes, foram cultivadas com meio de diferenciação contendo ácido retinóico (RA) e / ou meio condicionado testicular (TCC). As AT-MSCs expressaram marcadores de superfície mesenquimais e diferenciaram nas linhagens adipogênica, condrogênica e osteogênica. Após o tratamento com RA, somente as AT-MSCs isoladas do tecido adiposo depositado na região do omento expressaram um único importante marcador relacionado às células da linhagem germinativa masculina. Estes resultados reafirmam a importância do tecido adiposo como fonte de células-tronco estromais-multipotentes, bem como, uma fonte de MSCs para estudos de diferenciação.(AU)
Descritores: Tecido Adiposo
Células Germinativas
Fator Neurotrófico Derivado de Linhagem de Célula Glial/análise
Células-Tronco/classificação
Limites: Animais
Responsável: BR68.1 - Biblioteca Virginie Buff D'Ápice



página 1 de 1
   


Refinar a pesquisa
  Base de dados : Formulário avançado   

    Pesquisar no campo  
1  
2
3
 
           



Search engine: iAH v2.6 powered by WWWISIS

BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde