Base de dados : LILACS
Pesquisa : D12.776.157.530.400.175.781 [Categoria DeCS]
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Id: lil-741537
Autor: Lacerda, Adriana; Quintiliano, Juliana; Lobato, Diolen; Gonçalves, Claudia; Marques, Jair.
Título: Hearing Profile of Brazilian Forestry Workers' Noise Exposure
Fonte: Int. arch. otorhinolaryngol. (Impr.);19(1):22-29, Jan-Mar/2015. tab, graf.
Idioma: en.
Resumo: Introduction Researchers studying the hearing health of forestry workers have revealed the presence of a noise-induced hearing loss (NIHL) in this population and have concluded that the vibration of the equipment, the carbon monoxide released by motors, and pesticides might also contribute to NIHL. Objective To analyze the noise exposure in the Brazilian forestry industry workers and the effects on hearing. Methods The study sample comprised 109 employees of a company that specialized in reforestation. Their participants' mean age was 35.5 years (21 to 54 years), mean tenure at the company was 3.9 years (1 to 13 years), and mean total duration of noise exposure was 12.3 years (1 to 30 years). The existing documentation reporting on the jobs risk analysis was examined, noise level was measured, and pure tone audiometry was performed in all participants. Participants were divided into three groups according to their noise exposure levels in their current job. Results Of the participants who were exposed to noise levels less than 85 dBA (decibels with A-weighting filter), 23.8% had hearing loss, and 5.5% of the participants who were exposed to noise ranging from 85 to 89.9 dBA and 11% of the participants who were exposed to noise greater than 90 dBA had audiogram results suggestive of NIHL. Conclusion The implementation of a hearing loss prevention program tailored to forestry workers is needed. .
Descritores: Geradores de Padrão Central/fisiologia
Respiração
Receptores de GABA/metabolismo
Receptores da Glicina/metabolismo
Limites: Animais
Tipo de Publ: Comentário
Research Support, Non-U.S. Gov't
Responsável: BR1.1 - BIREME


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Id: lil-269466
Autor: Nuñez U., Gastón; Urzúa Urzúa, Jorge.
Título: Mecanismo de acción de los anestésicos generales: ¿efecto sobre proteínas de canales iónicos o sobre fosfolípidos de membrana? / Action mechanisms of general anesthetics: effect over ionic channel proteins or over membrane phospholipids?
Fonte: Rev. chil. anest;27(1):21-36, 1998. tab, graf.
Idioma: es.
Descritores: Anestésicos Gerais/farmacocinética
Canais Iônicos
Membranas/efeitos dos fármacos
-Canais de Cálcio/efeitos dos fármacos
Ácido gama-Aminobutírico/efeitos dos fármacos
Canais de Potássio/efeitos dos fármacos
Receptores Nicotínicos
Receptores de Glutamato/efeitos dos fármacos
Receptores da Glicina/efeitos dos fármacos
Canais de Sódio/efeitos dos fármacos
Limites: Humanos
Tipo de Publ: Revisão
Responsável: CL1.1 - Biblioteca Central


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Id: lil-199241
Autor: Cano, Georgina; Suárez Roca, Heberto; Bonilla, Ernesto.
Título: Manganese poisoning reduces strychnine-insensitive glycine binding sites in the globus pallidus of the mouse brain / Reducción de los receptores glicinérgicos insensibles a estricnina en el globo pálido del cerebro de ratones intoxicados con manganeso
Fonte: Invest. clín;37(4):209-19, dic. 1996.
Idioma: es.
Resumo: Manganese (Mn) poisoning is characterized by central nerous system manifestations, including psychiatric disturbances and estrapyramidal disorders. This metal is thought to produce neuronal degeneration due to cytotoxic products originated by oxidative stress and through an indirect excitotoxic process. In previous studies, we have found a reduction in the density of N-methyl-D-aspartate (NMDA) recognition sites in some brain areas of Mn-treated mice. Due to the close relationship between NMDA receptor complex, the [3H]-glycine ([3H]/Gly) binding was manganese choride for 8 weeks. Among all analyzed areas, only the globus pallidus showed a significant reduction in [3H]-Gly binding (27-28). The Gly binding decrease, focalized in the globus pallidus, could reflect a degeneration of structures containing strychnine-insensitive Gly receptors, since this area is the most frequently reported damaged brain region in Mn intoxication. Howerer, it might also be due to a Gly receptor down-regulation to control NMDA complex activation during Mn poisoning.
Descritores: Autorradiografia
Glicina/uso terapêutico
Manganês/toxicidade
Camundongos/anatomia & histologia
Receptores da Glicina/análise
Estricnina/análise
Limites: Camundongos
Tipo de Publ: Revisão
Responsável: VE1.1 - Biblioteca Humberto Garcia Arocha


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Id: lil-174121
Autor: Félix Grijalva, Diego Ricardo; Mazón Ramírez, Juan José.
Título: Canales para iones en las membranas celulares: algunos aspectos de interés clínico / Ionic channels in cellular membranes: somo aspects of clinical relevance
Fonte: Rev. méd. IMSS;33(1):107-11, ene.-feb. 1995. ilus.
Idioma: es.
Resumo: En el presente artículo se revisan brevemente las principales características de los canales para iones en las membranas celulares, su participación en diversos eventos fisiológicos y fisiopatológicos y se muestran ciertos aspectos de importancia clínica derivados de su estudio
Descritores: Canais de Cálcio/fisiologia
Canais Iônicos/fisiologia
Fibrose Cística/diagnóstico
Canais de Potássio/fisiologia
Receptores Colinérgicos/fisiologia
Receptores de GABA/fisiologia
Receptores de Glutamato/fisiologia
Receptores da Glicina/fisiologia
Canais de Sódio/fisiologia
Responsável: MX1.1 - CENIDSP - Centro de Información para Decisiones en Salud Pública



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