Base de dados : LILACS
Pesquisa : D12.776.395.560.631 [Categoria DeCS]
Referências encontradas : 71 [refinar]
Mostrando: 1 .. 10   no formato [Detalhado]

página 1 de 8 ir para página                    

  1 / 71 LILACS  
              next record last record
seleciona
para imprimir
Fotocópia
Texto completo SciELO Brasil
Almeida Junior, Hiram Larangeira de
Texto completo
Id: biblio-949950
Autor: Almeida Júnior, Hiram Larangeira de; Bicca, Eduardo de Barros Coelho; Andrade, Mariani Magnus de; Andrade Neto, Pedro da Rocha.
Título: Scanning electron microscopy of granuloma annulare
Fonte: An. bras. dermatol;93(5):740-742, Sept.-Oct. 2018. graf.
Idioma: en.
Resumo: Abstract: Light microscopy of granuloma annulare shows mucin deposition with lympho-histiocytic infiltrate. We describe the ultrastructural three-dimensional aspects of a typical case of granuloma with characteristic histopathological findings. At the ultrastructural level, affected collagen bundles and granular mucin deposition were observed. Round cells corresponding to lymphocytes were identified. Bigger oval cells, corresponding to isolated or palisading histiocytes were also found. The ultrastructural aspects overlap with light microscopy and contribute to its iconographic documentation.
Descritores: Microscopia Eletrônica de Varredura
Colágeno/ultraestrutura
Granuloma Anular/patologia
-Histiócitos/ultraestrutura
Mucinas/metabolismo
Limites: Seres Humanos
Tipo de Publ: Relatos de Casos
Responsável: BR1.1 - BIREME


  2 / 71 LILACS  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo SciELO Brasil
Texto completo
Id: biblio-1011112
Autor: Biondo, Giovanni; Sola, Simona; Pastorino, Carlotta; Massone, Cesare.
Título: Clinical, dermoscopic, and histologic aspects of two cases of cutaneous focal mucinosis
Fonte: An. bras. dermatol;94(3):334-336, May-June 2019. graf.
Idioma: en.
Resumo: Abstract: Cutaneous mucinoses are a complex and diverse group of connective tissue disorders characterized by the accumulation of mucin and/or glycosaminoglycan in the skin and adnexa. Cutaneous focal mucinosis appears as a solitary, asymptomatic, skin-colored to white papule, nodule, or plaque located anywhere on the body or in the oral cavity. It presents mainly in adults and is characterized on histopathology by mucin throughout the upper and mid dermis. We describe the dermoscopy of two cases of cutaneous focal mucinosis. Both lesions presented a nonspecific homogenous whitish pattern; the first case also exhibited a sharply demarcated yellow border.
Descritores: Dermatopatias/patologia
Mucinoses/patologia
-Dermoscopia
Glicosaminoglicanos
Mucinas
Limites: Seres Humanos
Masculino
Feminino
Meia-Idade
Tipo de Publ: Relatos de Casos
Responsável: BR1.1 - BIREME


  3 / 71 LILACS  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo SciELO Brasil
Texto completo
Id: biblio-1038307
Autor: Cárdenas-Gonzalez, Ramiro Eugenio; Ruelas, Maira Elizabeth Herz; Candiani, Jorge Ocampo.
Título: Lichen myxedematosus: a rare group of cutaneous mucinosis
Fonte: An. bras. dermatol;94(4):462-469, July-Aug. 2019. tab, graf.
Idioma: en.
Resumo: Abstract: Cutaneous mucinoses are a heterogeneous group of dermatoses in which excess deposition of mucin in the dermis gives the skin a waxy appearance, with papules and plaques that can vary from self-healing mucinosis to even disrupting the normal shape of a patient's face, conferring a leonine facies, or be part of life threatening diseases like scleromyxedema. This review will describe the most recent classification on lichen myxedematosus in the generalized (scleromyxedema) and the localized forms, as well as the different organ systems involved in scleromyxedema, diagnostic workup, current management, and prognosis.
Descritores: Dermatopatias/diagnóstico
Dermatopatias/patologia
Escleromixedema/diagnóstico
Escleromixedema/patologia
-Pele/patologia
Dermatopatias/classificação
Dermatopatias/terapia
Escleromixedema/classificação
Escleromixedema/terapia
Fibroblastos/patologia
Mucinas
Limites: Seres Humanos
Tipo de Publ: Revisão
Responsável: BR1.1 - BIREME


  4 / 71 LILACS  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo SciELO Brasil
Texto completo
Id: lil-706987
Autor: Passos, Paola C. Vieira da Rosa; Zuchi, Manuela Ferrasso; Fabre, Andréa Buosi; Martins, Luis Eduardo A. Machado.
Título: Follicular mucinosis - Case report
Fonte: An. bras. dermatol;89(2):337-339, Mar-Apr/2014. graf.
Idioma: en.
Resumo: Follicular mucinosis, also known as alopecia mucinosa, is a cutaneous mucinosis histologically characterized by accumulation of dermal type mucin in the pilosebaceous follicle and sebaceous glands. It presents in two forms, a primary or idiopathic form and a secondary form associated with various benign or malignant processes. Among the malignant processes, the main association is with mycosis fungoides. The frequent overlap of clinical, histopathological, immunohistochemical and molecular biology characteristics makes the correct classification of these conditions difficult, therefore a long follow-up of all cases is recommended. We report the case of an adolescent with disseminated lesions and discuss the difficulty of early identification of secondary follicular mucinosis associated with cutaneous lymphoma.
Descritores: Neoplasias Cutâneas/patologia
Micose Fungoide/patologia
Mucinose Folicular/patologia
-Mucinas/análise
Limites: Seres Humanos
Masculino
Adolescente
Tipo de Publ: Relatos de Casos
Responsável: BR1.1 - BIREME


  5 / 71 LILACS  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo SciELO Brasil
Texto completo
Id: biblio-837997
Autor: Rebellato, Priscila Regina Orso; Carbonar, Mauren Beatriz Frazon; Tabuti, Nicole Iasmin Magario; Rastelli, Graziela Junges Crescente.
Título: Case for diagnosis. Lichen myxedematosus
Fonte: An. bras. dermatol;91(6):842-843, Nov.-Dec. 2016. graf.
Idioma: en.
Resumo: Abstract Scleromyxedema or lichen myxedematosus is a rare papular mucinosis of chronic and progressive course and unknown etiology. It is commonly associated with monoclonal gammopathy and may show extracutaneous manifestations, affecting the heart, lung, kidney, and nerves. The diagnosis is based on four criteria: generalized papular and sclerodermoid lesions; mucin deposition, fibroblast proliferation, and fibrosis in the histopathology; monoclonal gammopathy; and no thyroid disorders. This article reports the case of a scleromyxedema patient with a recent history of acute myocardial infarction and monoclonal gammopathy.
Descritores: Derme/patologia
Escleromixedema/patologia
-Proliferação Celular
Fibroblastos/patologia
Mucinas
Limites: Seres Humanos
Masculino
Meia-Idade
Tipo de Publ: Relatos de Casos
Responsável: BR1.1 - BIREME


  6 / 71 LILACS  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo SciELO Brasil
Texto completo
Id: biblio-837963
Autor: Bousquet Muylaert, Bianca Pinheiro; Braga, Bruna Backsmann; Esteves, Eduarda Braga; Garbelini, Luciana Elisa Barandas; Michalany, Alexandre Ozores; Oliveira Filho, Jayme de.
Título: Lupus tumidus: a report of two cases
Fonte: An. bras. dermatol;91(5,supl.1):87-89, Sept.-Oct. 2016. graf.
Idioma: en.
Resumo: Abstract Lupus tumidus is considered a rare subtype of chronic cutaneous lupus erythematosus, characterized by erythema and bright urticarial erythematous-violaceous lesions that leave no scars after regression. Histopathology reveals perivascular and periannexal lymphohistiocytic infiltrates in the papillary and reticular dermis and interstitial mucin deposition. Treatment is based on photoprotection, topical corticosteroids and antimalarials. We report two cases of lupus tumidus, which deserve attention for their low frequency in the literature, in addition to their relevance as a differential diagnosis among dermatologic disorders.
Descritores: Pele/patologia
Lúpus Eritematoso Cutâneo/patologia
-Biópsia
Lúpus Eritematoso Cutâneo/tratamento farmacológico
Prednisona/uso terapêutico
Cloroquina/uso terapêutico
Resultado do Tratamento
Glucocorticoides/uso terapêutico
Mucinas
Antimaláricos/uso terapêutico
Limites: Seres Humanos
Feminino
Meia-Idade
Tipo de Publ: Relatos de Casos
Responsável: BR1.1 - BIREME


  7 / 71 LILACS  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo SciELO Brasil
Texto completo
Id: biblio-837957
Autor: Sala, Ana Carolina Bulhões; Cunha, Paulo Rowilson; Pinto, Clóvis Antônio Lopes; Alves, Célia Antônia Xavier de Moraes; Paiva, Ingrid Barreto; Araujo, Ana Paula Vieira.
Título: Scleromyxedema: clinical diagnosis and autopsy findings
Fonte: An. bras. dermatol;91(5,supl.1):48-50, Sept.-Oct. 2016. graf.
Idioma: en.
Resumo: Abstract Scleromyxedema is a rare chronic cutaneous mucinosis of unknown etiology. It is characterized by papular eruption and scleroderma with microscopic evidence of mucin deposition, fibroblast proliferation, and fibrosis. Most patients with scleromyxedema have monoclonal gammopathy and systemic manifestations resulting in significant morbidity and mortality. Several types of treatment have been reported with partial or inconsistent responses. Despite showing unpredictable evolution, systemic consequences of scleromyxedema and treatment side effects may result in death. We describe a rare case of a patient with scleromyxedema without paraproteinemia with systemic involvement that evolved to death despite treatment with cyclophosphamide.
Descritores: Pele/patologia
Escleromixedema/patologia
-Biópsia
Evolução Fatal
Mucinas/metabolismo
Limites: Seres Humanos
Masculino
Meia-Idade
Tipo de Publ: Relatos de Casos
Responsável: BR1.1 - BIREME


  8 / 71 LILACS  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo SciELO Brasil
Texto completo
Id: biblio-837914
Autor: Gómez Sánchez, María Encarnación; Manueles Marcos, Fernando de; Martínez Martínez, Maria Luisa; Vera Berón, Roberto; Azaña Défez, Jose Manuel.
Título: Acral papular mucinosis: a new case of this rare entity
Fonte: An. bras. dermatol;91(5,supl.1):111-113, Sept.-Oct. 2016. graf.
Idioma: en.
Resumo: Abstract Acral persistent papular mucinosis (APPM) is a rare subtype of localized lichen myxedematosus. It consists of small papules localized exclusively on the back of the hands, wrists and extensor aspects of distal forearms with no other clinical or laboratory manifestations. The lesions tend to persist and may increase slowly in number. Histologically, hematoxylin-eosin and Alcian blue staining demonstrate mucin accumulation in the upper reticular dermis with separation of collagen fibers as a result of hyaluronic acid deposition. Treatment is rarely necessary due to the absence of symptoms. We present a 27-year-old healthy woman with asymptomatic papules on her upper extremities, which adequately meet clinical and pathological criteria of acral papular mucinosis.
Descritores: Pele/patologia
Dermatopatias/patologia
Escleromixedema/patologia
-Biópsia
Extremidade Superior
Doenças Raras
Mucinas/análise
Limites: Seres Humanos
Feminino
Adulto
Tipo de Publ: Relatos de Casos
Responsável: BR1.1 - BIREME


  9 / 71 LILACS  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo SciELO Brasil
Coy, Cláudio Saddy Rodrigues
Texto completo
Id: biblio-837695
Autor: Alves Júnior, Antonio José Tiburcio; Pereira, José Aires; Pansani, Adrieli Heloísa Campardo; Magro, Daniela Oliveira; Coy, Cláudio Saddy Rodrigues; Martinez, Carlos Augusto Real.
Título: Tissue sulfomucin and sialomucin content in colon mucosa without intestinal transit subjected to intervention with Curcuma longa (curcumin)
Fonte: Acta cir. bras;32(3):182-193, Mar. 2017. tab, graf.
Idioma: en.
Projeto: FAPESP.
Resumo: Abstract Purpose: To measure the tissue sulfomucin and sialomucin content of the colon mucosa without fecal flow, subjected to intervention with curcumin, and the influence of the concentration used and the intervention time. Methods: Thirty-six rats were subjected to proximal right colostomy and distal mucous fistula. They were divided into two groups according to whether sacrifice was performed two or four weeks after the intervention. Each group was divided into three subgroups according to the enema applied daily: saline alone; curcumin at 50 mg/kg/day or curcumin at 200 mg/kg/day. Acid mucins were diagnosed using the Alcian blue technique. The mucin content was quantified by means of computer-assisted image analysis. The significance level of 5% was used throughout (p < 0.05). Results: There were dose-related increases in the quantities of sulfomucins in the animals subjected to interventions with curcumin, both after two weeks (p < 0.00001) and after four weeks (p < 0.00001). There were increases in sialomucin quantity that were concentration-related (p < 0.00001) and time-related (p < 0.00001). Conclusion: Curcumin enemas increase the quantity of acid mucins in the intestinal flow in the excluded colon, with dose and time dependency.
Descritores: Extratos Vegetais/administração & dosagem
Colo/efeitos dos fármacos
Colo/química
Mucosa Intestinal/efeitos dos fármacos
Mucosa Intestinal/química
Mucinas/análise
-Valores de Referência
Fatores de Tempo
Processamento de Imagem Assistida por Computador
Óleos Vegetais/administração & dosagem
Trânsito Gastrointestinal/efeitos dos fármacos
Colostomia
Reprodutibilidade dos Testes
Ratos Wistar
Colite/patologia
Colite/tratamento farmacológico
Colo/patologia
Curcuma
Enema/métodos
Sialomucinas/efeitos dos fármacos
Fezes
Mucosa Intestinal/patologia
Mucinas/efeitos dos fármacos
Limites: Animais
Masculino
Tipo de Publ: Estudos de Avaliação
Responsável: BR1.1 - BIREME


  10 / 71 LILACS  
              first record previous record
seleciona
para imprimir
Fotocópia
Texto completo
Id: biblio-882194
Autor: Almeida, Maisa Camillo Jordão.
Título: Estabelecimento de protocolos in vitro e in situ para estudos de erosão dentária / Establishment of in vitro and in situ protocols for dental erosion studies.
Fonte: Bauru; s.n; 2016. 122 p. tab, ilus.
Idioma: pt.
Tese: Apresentada a Universidade de São Paulo. Faculdade de Odontologia de Bauru para obtenção do grau de Doutor.
Resumo: O objetivo foi comparar uma formulação de saliva artificial com e sem mucina (in vitro) com a saliva humana (in situ) na inibição da desmineralização (subprojeto I) e no reendurecimeto de lesões de erosão (subprojeto II), e a influência do tipo de dispositivo intrabucal (mandibular X palatino) no desgaste erosivo do esmalte (subprojeto III). No subprojeto I, blocos de esmalte bovino foram selecionados pela dureza de superfície e randomizados entre os grupos: GI - saliva humana (n=30), GII - saliva artificial sem mucina (n=15), GIII - saliva artificial com mucina (n=15) e GIV - água deionizada (n=15). Quinze voluntários utilizaram o dispositivo palatino por um período 2 horas (GI). Nos grupos GII, GIII e GIV, os blocos foram imersos em suas respectivas soluções por um período de 2 horas. Imediatamente após, tanto os blocos do grupo in situ quanto dos grupos in vitro foram submetidos ao desafio erosivo inicial com ácido cítrico 1% (pH 3,6) por 4 minutos. A microdureza final foi mensurada para determinar a porcentagem de perda de dureza. No subprojeto II, os blocos, após seleção, foram erodidos in vitro e randomizados entre grupos como no subprojeto I. Para a erosão, os blocos foram imersos em ácido cítrico 1% (pH 3,6) por 4 minutos. A seguir, no grupo GI, 15 voluntários utilizaram dispositivos palatinos durante 2 horas. Nos outros grupos os blocos foram imersos nas salivas artificiais com (GIII) e sem mucina (GII) e água deionizada (GIV) por 2 horas. A precipitação de minerais sobre o esmalte foi avaliada por meio da porcentagem de recuperação de dureza. No subprojeto III, após seleção dos blocos pela dureza, os mesmos foram aleatorizados em 2 grupos (n=20): GI - dispositivo palatino e GII - dispositivo mandibular. A ciclagem consistiu na imersão dos dois dispositivos em ácido clorídrico 0,01 M (pH 2,3) por 2 minutos, 4X/dia durante 5 dias. A perda do esmalte foi avaliada por perfilometria e os voluntários responderam a um questionário quanto ao conforto dos dispositivos. Nos subprojetos I e II, os dados foram submetidos aos testes ANOVA e Tukey e no subprojeto III foi aplicado o Teste T pareado (p<0,05). Nos subprojetos I e II observou-se que todas as salivas estudadas foram capazes de promover uma recuperação de dureza do esmalte e nenhuma diferença foi encontrada entre elas (p<0,05). No ensaio de desmineralização, a saliva artificial com mucina e a saliva humana (in situ) promoveram menor perda de dureza, não mostrando diferença entre elas (p<0,05). No subprojeto III os resultados mostraram que os blocos localizados no dispositivo palatino (GI) apresentaram maior desgaste erosivo quando comparados aos do dispositivo mandibular (GII). Além disso, todos voluntários relataram maior conforto no uso do dispositivo palatino. Considerando que o dispositivo palatino é mais confortável e resultou em maior perda de esmalte quando comparado ao mandibular, sugere-se o uso de dispositivos palatinos em protocolos in situ que queiram mimetizar pacientes com alto risco de erosão dentária. Para estudos in vitro, a saliva com mucina mostrou-se como uma boa substituta à saliva humana.(AU)

The aim was to compare artificial saliva formulation with and without mucin (in vitro) with human saliva (in situ) on the inhibition of erosive demineralization (subproject I) and on the rehardening of erosion lesions (subproject II), and analyze the influence of the type of intraoral appliance (mandibular X maxillary) in enamel wear caused by erosive challenges (subproject III). In the subproject I, bovine enamel blocks were selected by initial surface hardness and randomized among the groups: GI - human saliva (n=30), GII - artificial saliva without mucin (n=15), GIII - artificial saliva with mucin (n=15) and GIV - deionized water (n=15). Fifteen volunteers wore palatal appliances for 2 hours (GI). In the GII, GIII and GIV groups, the blocks were immersed to the respective solutions for 2 hours. Subsequently, both in vitro and in situ blocks were subjected to initial erosive challenge in 1% citric acid (pH 3.6) for 4 minutes. Final enamel hardness was measured to determine the protective capacity of saliva tested by percentage of hardness loss. For the subproject II, after blocks selection, they were in vitro eroded and randomly among the groups as in subproject I. For erosion, the enamel blocks were immersed on 1% citric acid (pH 3.6) for 4 minutes. Then, in the GI, 15 volunteers wore palatal appliances for 2 hours. In the other groups the blocks were immersed in artificial saliva with (GIII) and without mucin (GII) and deionized water (GIV) for 2 hours. The minerals precipitation on the enamel was evaluated by the percentage of hardness recovery. On subproject III, after enamel blocks selection by surface hardness, they were randomly divided into 2 groups (n=20): GI - palatine appliance and GII - mandibular appliance. Erosive cycling consists in immersing of both devices in 0.01 M hydrochloric acid (pH 2.3) for 2 minutes, 4X/day during 5 days. The analysis of the wear was measured by profilometry and volunteers answered a questionnaire about the comfort of the devices. In the subprojects I and II, data were analyzed by one-way ANOVA and Tukeys test, and in the subproject III It was applied paired t-test (p <0.05). In subprojects I and II it was observed that all studied saliva promoted enamel rehardening and no difference was found between them (p <0.05). In the demineralization test, the artificial saliva with mucin and human saliva (in situ) provided lower enamel hardness loss, showing no difference between them (p<0.05). In the subproject III, the results showed that the specimens allocated in palatine appliance (GI) presented significantly higher erosive wear when compared to the specimens fixed in mandibular appliance (GII). In addition, all volunteers reported greater comfort in using the palatal device. Considering the palatal device is more comfortable and resulted in higher enamel loss when compared to the mandibular device, it is suggested the use of palatine appliances in in situ protocols who want to mimic a patient at high risk of dental erosion. For in vitro studies, the saliva with mucin might be a good substitute for human saliva.(AU)
Descritores: Esmalte Dentário/química
Mucinas/química
Saliva Artificial/química
Saliva/química
Desmineralização do Dente/prevenção & controle
Erosão Dentária/prevenção & controle
-Análise de Variância
Modelos Dentários
Testes de Dureza
Reprodutibilidade dos Testes
Propriedades de Superfície
Limites: Seres Humanos
Animais
Masculino
Feminino
Adolescente
Adulto
Bovinos
Tipo de Publ: Estudo Comparativo
Estudos de Avaliação
Responsável: BR28.1 - Serviço de Biblioteca e Documentação Professor Doutor Antônio Gabriel Atta



página 1 de 8 ir para página                    
   


Refinar a pesquisa
  Base de dados : Formulário avançado   

    Pesquisar no campo  
1  
2
3
 
           



Search engine: iAH v2.6 powered by WWWISIS

BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde