Base de dados : LILACS
Pesquisa : D20.888.065.970 [Categoria DeCS]
Referências encontradas : 21 [refinar]
Mostrando: 1 .. 10   no formato [Detalhado]

página 1 de 3 ir para página          

  1 / 21 LILACS  
              next record last record
seleciona
para imprimir
Fotocópia
Texto completo SciELO Brasil
Texto completo
Id: biblio-1279405
Autor: Alberto-Silva, Carlos; Portaro, Fernanda Calheta Vieira; Kodama, Roberto Tadashi; Pantaleão, Halyne Queiroz; Rangel, Marisa; Nihei, Ken-ichi; Konno, Katsuhiro.
Título: Novel neuroprotective peptides in the venom of the solitary scoliid wasp Scolia decorata ventralis
Fonte: J. venom. anim. toxins incl. trop. dis;27:e20200171, 2021. tab, graf.
Idioma: en.
Resumo: Background Solitary wasp venoms may be a rich source of neuroactive substances, since their venoms are used for paralyzing preys. We have been exploring bioactive constituents of solitary wasp venoms and, in this study, the component profile of the venom from a solitary scoliid wasp, Scolia decorata ventralis, was investigated through a comprehensive analysis using LC-MS. Two peptides were synthesized, and their neuroprotective properties were evaluated. Methods A reverse-phase HPLC connected to ESI-MS was used for LC-MS analyses. Online mass fingerprinting was performed from TIC, and data-dependent tandem mass spectrometry gave the MS/MS spectra. The sequences of two major peptide components were determined by MALDI-TOF/TOF MS analysis, confirmed by solid phase synthesis. Using the synthetic peptides, biological activities were assessed. Cell integrity tests and neuroprotection analyzes using H2O2 as an oxidative stress inducer were performed for both peptides. Results Online mass fingerprinting revealed that the venom contains 123 components, and the MS/MS analysis resulted in 33 full sequences of peptide components. The two main peptides, α-scoliidine (DYVTVKGFSPLR) and β-scoliidine (DYVTVKGFSPLRKA), present homology with the bradykinin C-terminal. Despite this, both peptides did not behave as substrates or inhibitors of ACE, indicating that they do not interact with this metallopeptidase. In further studies, β-scoliidine, but not α -scoliidine, showed protective effects against oxidative stress-induced neurotoxicity in PC12 cells through integrity and metabolism cell assays. Interestingly, β-scoliidine has the extension of the KA dipeptide at the C-terminal in comparison with α-scoliidine. Conclusion Comprehensive LC-MS and MS/MS analyses from the Scolia decorata ventralis venom displayed the component profile of this venom. β-scoliidine showed an effective cytoprotective effect, probably due to the observed increase in the number of cells. This is the first report of solitary wasp venom peptides showing neuroprotective activity.(AU)
Descritores: Peptídeos/classificação
Venenos de Vespas
Vespas/metabolismo
Neuroproteção
-Estresse Oxidativo
Espectrometria de Massas por Ionização e Dessorção a Laser Assistida por Matriz
Limites: Animais
Responsável: BR68.1 - Biblioteca Virginie Buff D'Ápice


  2 / 21 LILACS  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo SciELO Costa Rica
Texto completo
Texto completo
Id: biblio-1098365
Autor: Rodríguez Lara, Andrés Gerardo; Aguilar Pérez, Jorge.
Título: Accidente por himenópteros: reporte de caso / Hymenoptera accident: case report
Fonte: Med. leg. Costa Rica;37(1):6-11, ene.-mar. 2020. graf.
Idioma: es.
Resumo: Resumen Los himenópteros es una de las clasificaciones de los insectos, constituida por principalmente tres tipos, la abeja, la avispa y la hormiga de fuego, que provocan picaduras con veneno, generando desde efectos locales hasta sistémicos, con repercusiones leves o mortales sino reciben una atención médica oportuna. Las reacciones sistémicas son dependientes de la respuesta inmunológica, así como de la cantidad de las picaduras. Se presentaran dos casos de fallecimiento a causa de accidente por himenópteros tipo abejas, diagnosticados por la historia médicolegal, hallazgos de autopsia relacionado al efecto sistémico del veneno de las abejas y circunstancias relacionadas a la muerte.

Abstract Hymenoptera is one of the classifications of insects, consisting mainly of three types, the bee, the wasp and the fire ant, which cause pitting with venom generating from local to systemic effects, with slight or fatal repercussions but receive timely medical attention. Systemic reactions are dependent on the immune response, as well as the number of bites. There will be two cases of death due to an accident by hymenopterans type bees, diagnosed by medical-legal history, autopsy findings related to the systemic effect of bee venom and circumstances related to death will be presented.
Descritores: Venenos de Vespas
Vespas
Mordeduras e Picadas de Insetos/complicações
-Costa Rica
Himenópteros
Limites: Humanos
Idoso
Tipo de Publ: Relatos de Casos
Responsável: CR1.1 - BINASSS - Biblioteca Nacional de Salud y Seguridad Social


  3 / 21 LILACS  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Cardoso, Joäo Luiz Costa
Wen, Fan Hui
Id: lil-317783
Autor: França, Francisco Oscar de Siqueira; Cardoso, Joäo Luiz Costa; Wen, Fan Hui.
Título: Acidentes por aracnídeos e insetos / Accident for arachnids and insect
Fonte: In: Veronesi, Ricardo; Focaccia, Roberto. Tratado de infectologia: v.2. Säo Paulo, Atheneu, 2002. p.1570-1580, ilus, tab. (BR)
Idioma: pt.
Símbolo: BR.
Descritores: Aracnídeos
Venenos de Aranha
Mordeduras e Picadas de Insetos
-Tartarugas
Venenos de Vespas
Venenos de Abelha
Venenos de Formiga
Mariposas
Himenópteros
Venenos de Escorpião
Responsável: BR31.1 - SIDC - Serviço de Informação e Documentação Científica
BR31.1; WC100, V599t, 2.ed., v.2


  4 / 21 LILACS  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo SciELO Brasil
Texto completo
Id: lil-724686
Autor: Jalaei, Jafar; Fazeli, Mehdi; Rajalan, Hamid; Shahram, Seyed.
Título: In vitro antibacterial effect of wasp (Vespa orientalis) venom
Fonte: J. venom. anim. toxins incl. trop. dis;20, 04/02/2014.
Idioma: en.
Resumo: The emergence of antibacterial resistance against several classes of antibiotics is an inevitable consequence of drug overuse. As antimicrobial resistance spreads throughout the globe, new substances will always be necessary to fight against multidrug-resistant microorganisms. Venoms of many animals have recently gained attention in the search for new antimicrobials to treat infectious diseases. Thefore, the present study aimed to study the antibacterial effects of wasp (Vespa orientalis) crude venom. Two gram-positive bacteria (Staphylococcus aureus and Bacillus subtilis) and two gram-negative ones (Escherichia coli and Klesiella pneumonia) were compared for their sensitivity to the venom by determining the inhibition zone (Kirby-Bauer method) and minimum inhibitory concentration (MIC). A microbroth kinetic system based on continuous monitoring of changes in the optical density of bacterial growth was also used for determination of antimicrobial activity.
Descritores: Antibacterianos/análise
Venenos
Venenos de Vespas/análise
-Vespas/classificação
Limites: Animais
Responsável: BR68.1 - Biblioteca Virginie Buff D'Ápice


  5 / 21 LILACS  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo SciELO Brasil
Texto completo
Id: lil-686623
Autor: Nadolski, Jerzy.
Título: Effects of the European hornet ( Vespa crabro Linnaeus 1761) crude venom on its own species
Fonte: J. venom. anim. toxins incl. trop. dis;19:1-4, maio 2013. tab.
Idioma: en.
Resumo: Background Lethal dose 50% is a classical index of toxicity that usually employs small rodents as experimental animals. Therefore, scarce data are available on the effects of venom on invertebrates, particularly the impact of wasp venom on its own species. Findings In the present study, the lethality of Vespa crabro venom on its own species was studied. Lethal dose 50% values of crude venom on workers of hornet Vespa crabro were estimated to be 4.0 mg/kg of body weight. Conclusions Wasps can use their venom apparatus effectively when attacking foreign workers that appear in the immediate vicinity of their nest. The toxins released during stinging are potent enough to kill. The result of this study eliminates the popular myth that venomous animals can be resistant to their own venom.(AU)
Descritores: Vespa crabro/envenenamento
Venenos de Vespas/toxicidade
-Dose Letal Mediana
Limites: Animais
Responsável: BR1.1 - BIREME


  6 / 21 LILACS  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
Id: lil-663334
Autor: Santos, Sónia; Loureiro, Carla Chaves.
Título: Alergia a veneno de himenópteros na criança / Hymenoptera venom allergy in children
Fonte: Sci. med;22(4), out.-dec. 2012. tab, graf.
Idioma: pt.
Resumo: Objetivos: A alergia a veneno de himenópteros pode condicionar a vida da criança de forma significativa. Pretende-se, com a exposição de dois casos clínicos e uma breve revisão do tema, salientar a importância da referenciação dessas crianças a consultas especializadas, para início de dessensibilização.Descrição dos casos: Duas crianças, aos três e aos seis anos, tiveram anafilaxia a picada de vespa e abelha, respectivamente. Em ambas, após a determinação de IgE específica e confirmação alergológica, iniciou-se dessen-sibilização com veneno de himenópteros em esquema ultra-rush, sem intercorrências relevantes, apenas edema no local da injeção. Após doze meses de injeções a cada quatro semanas, recebem agora manutenção com injeções a cada seis semanas. No primeiro caso, a criança foi picada por vespa aos dez meses de imunoterapia, desencadeando apenas reação local diminuta.Conclusões: Em ambos os casos, a imunoterapia específica subcutânea com veneno em esquema ultra-rush foisegura e eficaz, oferecendo o conforto de um menor número de injeções e de deslocamentos ao hospital na fasede indução. A manutenção da terapêutica já demonstrou efeito protetor na reexposição ao veneno em uma dascrianças.

clinical cases and a brief review on the topic, emphasizing the importance of referral of these children to specialized care for early desensitization.Cases description: Two children, at three and six years, had anaphylactic reaction to wasp and bee stings, respectively. In both cases, after the determination of specific IgE and allergologic confirmation, desensitization with hymenoptera venom in ultra-rush regimen was done, without relevant side effect apart from swelling at the injection site. After twelve months of injections every four weeks, the children are now receiving maintenance injections every six weeks. In the first case, the child was stung by wasp at ten months of immunotherapy, triggering only small localreaction.Conclusions: In both cases, the subcutaneous venom immunotherapy with ultra-rush regimen was safe and effective, providing the comfort of a smaller number of injections and hospital visits during the induction phase. Maintenance therapy has demonstrated a protective effect on re-exposure to the poison in one child.
Descritores: Alergia e Imunologia
Venenos de Abelha
Dessensibilização Imunológica
Himenópteros
Hipersensibilidade
Imunoterapia
Venenos de Vespas
Tipo de Publ: Relatos de Casos
Responsável: BR500.1 - Biblioteca


  7 / 21 LILACS  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
Id: lil-653076
Autor: Oliveira, Agda Maria.
Título: Distribuição espacial e temporal de abelhas melíferas africanizadas e vespídeos (Hymenoptera) na Cidade de São Paulo / Spatial and temporal distribution of Africanized honey bees and Vespidae (Hymenoptera) in São Paulo.
Fonte: São Paulo; s.n; 2007. 75 p. ilus, tab.
Idioma: pt.
Tese: Apresentada a Universidade de São Paulo. Faculdade de Saúde Pública para obtenção do grau de Mestre.
Descritores: Abelhas/crescimento & desenvolvimento
Abelhas
Ecologia
EPIDEMIOLOGICAL SURVEILLANCE
Himenópteros
Himenópteros/crescimento & desenvolvimento
Mordeduras e Picadas de Insetos
Vespas/crescimento & desenvolvimento
Venenos de Vespas
Vespas
Limites: Humanos
Animais
Responsável: BR58.1 - Biblioteca
BR58.1; 638.12, O48d. 1190


  8 / 21 LILACS  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo SciELO Brasil
Texto completo
Id: lil-623499
Autor: Santos, L. D; Pieroni, M; Menegasso, A. R. S; Pinto, J. R. A. S; Palma, M. S.
Título: A new scenario of bioprospecting of Hymenoptera venoms through proteomic approach
Fonte: J. venom. anim. toxins incl. trop. dis;17(4):364-377, 2011. ilus.
Idioma: en.
Resumo: Venoms represent a huge and essentially unexplored reservoir of bioactive components that may cure diseases that do not respond to currently available therapies. This review select advances reported in the literature from 2000 to the present about the new scenario of Hymenoptera venom composition. On account of new technologies in the proteomic approach, which presents high resolution and sensitivity, the combination of developments in new instruments, fragmentation methods, strategic analysis, and mass spectrometry have become indispensable tools for interrogation of protein expression, molecule interaction, and post- translational modifications. Thus, the biochemical characterization of Hymenoptera venom has become a major subject of research in the area of allergy and immunology, in which proteomics has been an excellent alternative to assist the development of more specific extracts for diagnosis and treatment of hypersensitive patients to Hymenoptera venoms.
Descritores: Venenos de Abelha
Espectrometria de Massas/métodos
Himenópteros
Hipersensibilidade
Proteômica
Venenos de Vespas
Limites: Animais
Tipo de Publ: Revisão
Responsável: BR33.1 - Divisão Técnica de Biblioteca e Documentação


  9 / 21 LILACS  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Id: lil-618720
Autor: Díaz Gallardo, Carolina; Marinovi Mayorga, Angélica; Salinas Luypaert, Jessica.
Título: Alergia al venono de himenópteros / Hymenoptera venom allergy
Fonte: Arch. alerg. inmunol. clin;39(2):64-73, 2008.
Idioma: es.
Resumo: La alergia al veneno de himenópteros es un hecho epidemiológicamente significativo. Alrededor del 0.15% al 3% de la población general tiene historia de reacciones sistémicas causada por picaduras de insectos. Entre los himenópteros más comunes que provocan este tipo de reacciones se encuentran: abejas, abejorros, avispas y hormigas. Las manifestaciones clínicas varian desde reacciones locales (eritema, edema, prurito o dolor) hasta reacciones sitémicas, e incluso shock anafilçactico con riesgo vital. El manejo inmediato depende de la intensidad de la reacción y abarca desde la aplicaión de frío local y el uso de antihistamínicos orales y corticoides tópicos y orales hasta, en los casos más severos, la administración de adrenaina inyectable. En relación con el tratamiento a largo plazo, la inmunoterapia específica ha demostrado ser muy efectiva en la reducción del riesgo de reacción severa frente a la posterior picadura de insecto.
Descritores: Venenos de Abelha
Hipersensibilidade/complicações
Hipersensibilidade/diagnóstico
Hipersensibilidade/tratamento farmacológico
Venenos de Vespas
-Adjuvantes Imunológicos
Formigas
Reações Cruzadas
Responsável: AR144.1 - CIBCHACO - Centro de Información Biomedica del Chaco


  10 / 21 LILACS  
              first record previous record
seleciona
para imprimir
Fotocópia
Texto completo SciELO Brasil
Texto completo
Id: lil-587780
Autor: Vinhote, J. F. C; Torres, A. F. C; Dantas, R. T; Praciano, T. P; Menezes, R. R. P. P. B; Sousa, D. F; Brito, T. S; Lima, F. J. B; Toyama, M. H; Magalhães, P. J; Monteiro, H. S. A; Martins-Nunes, A. M. C.
Título: Renal- and calcium-dependent vascular effects of Polybia paulista wasp venom
Fonte: J. venom. anim. toxins incl. trop. dis;17(2):199-208, 2011. ilus, graf, tab.
Idioma: en.
Resumo: In the present study, the effects of Polybia paulista venom (PPV) on renal and vascular tissues were investigated. Isolated kidneys perfused with PPV (1 and 3 ìg/mL) had increased perfusion pressure, renal vascular resistance, urinary flow, and glomerular filtration rate; and reduced sodium tubular transport. Histological evaluation demonstrated deposits of proteins in Bowman's space and tubular lumen, and focal areas of necrosis. The venom promoted a cytotoxic effect on Madin-Darby canine kidney (MDCK) cells. A significant increase in lactic dehydrogenase levels was observed in response to venom exposure. In isolated mesenteric vascular beds, pressure and vascular resistance augmented in a dose-dependent manner. PPV increased the contractility of aortic rings maintained under basal tension. This contractile response was inhibited when preparations were maintained in Ca2+-free medium. Likewise, verapamil, a voltage-gated calcium channel blocker, also inhibited the contractile response. In this study, phentolamine, a blocker of á-adrenergic receptor blocker, significantly reduced the contractile effect of PPV in the aortic ring. In conclusion, PPV produced nephrotoxicity, which suggests a direct effect on necrotic cellular death in renal tubule cells. The vascular contractile effect of PPV appears to involve calcium influx through voltage-gated calcium channels via adrenergic regulation.
Descritores: Aorta
Bloqueadores dos Canais de Cálcio
Rim
Venenos de Vespas
-Fentolamina
Ratos Wistar
Verapamil
Limites: Animais
Ratos
Responsável: BR33.1 - Divisão Técnica de Biblioteca e Documentação



página 1 de 3 ir para página          
   


Refinar a pesquisa
  Base de dados : Formulário avançado   

    Pesquisar no campo  
1  
2
3
 
           



Search engine: iAH v2.6 powered by WWWISIS

BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde