Base de dados : LILACS
Pesquisa : D27.505.954.427 [Categoria DeCS]
Referências encontradas : 21 [refinar]
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Id: biblio-846386
Autor: Sánchez-Hervás, Emilio.
Título: Cocaine addiction: treatments and future perspectives / Adição a cocaína: tratamentos e perspectivas futuras
Fonte: Trends psychiatry psychother. (Impr.);38(4):242-243, Oct.-Dec. 2016.
Idioma: en.
Descritores: Transtornos Relacionados ao Uso de Cocaína/terapia
-Fármacos do Sistema Nervoso Central/uso terapêutico
Transtornos Relacionados ao Uso de Cocaína/diagnóstico
Limites: Seres Humanos
Responsável: BR1.1 - BIREME


  2 / 21 LILACS  
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Id: biblio-887478
Autor: Marín Gabriel, Miguel A; Malalana Martínez, Ana M; Olza Fernández, Ibone.
Título: Lactancia materna y tratamiento con litio: Caso clínico / Lithium while breastfeeding: Case report
Fonte: Arch. argent. pediatr;116(2):319-321, abr. 2018. tab.
Idioma: es.
Resumo: El tratamiento con litio forma parte de la terapia habitual en las personas que sufren el trastorno bipolar. Habitualmente, aquellas madres que desean dar el pecho a sus hijos son sometidas a la disyuntiva entre modificar el tratamiento o bien administrar lactancia artificial. La administración de litio durante la lactancia materna se ha asociado con diversos efectos adversos en el lactante, tales como alteraciones tiroideas, hipotermia o hipotonía, entre otros. Son pocas las publicaciones en las que no se observan dichas anomalías en los lactantes. A continuación, se presenta el caso de un lactante amamantado por su madre en tratamiento con litio que no presentó alteraciones renales ni tiroideas.

Lithium therapy is currently a cornerstone of treatment for mothers who suffer bipolar disorders. Those who wish to breastfeed their children are often told they have to decide whether modifying the treatment for their disorder or even avoiding lactation. Lithium administration during breastfeeding has been described to produce certain side effects such as thyroid disorders, hypothermia and hypotonia. To our knowledge, there are few publications where infants have no laboratory abnormalities. Here we present the case of an infant without renal or thyroid alteration while he was breastfed.
Descritores: Transtorno Bipolar/tratamento farmacológico
Aleitamento Materno
Fármacos do Sistema Nervoso Central/uso terapêutico
Carbonato de Lítio/uso terapêutico
Limites: Seres Humanos
Feminino
Recém-Nascido
Adulto
Tipo de Publ: Relatos de Casos
Responsável: AR94.1 - Centro de Información Pediatrica


  3 / 21 LILACS  
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Id: lil-623964
Autor: Zhu, Xing-Zu.
Título: Development of natural products as drugs acting on central nervous system
Fonte: Mem. Inst. Oswaldo Cruz;86(supl.2):173-175, 1991.
Idioma: en.
Conferência: Apresentado em: Brazilian-Sino Symposium on Chemistry and Pharmacology of Natural Products, Rio de Janeiro, Dec. 10-14, 1989.
Resumo: We have recenty studied several natural product constituents which have effects on the CNS. (1) Tetrahydropalmatine (THP) and its analogues were isolated from Corydalis ambigua and various species of Stephania. (+)-THP and (-)-THP posses not only analgesic activity, but also exert sedative-tranquillizing and hypnotic actions. Results of receptor binding assay and their pre-and post-synaptic effects on dopaminergic system indicate that (-)-THP and (-)-stepholidine are dopamine receptor antagonists while (+)-THP is a selective dopamine depletor. (2) 3-Acetylaconitine (AAC) is an alkaloid isolated from Aconitum flavum. The relative potency of analgesic action of AAC was 5.1-35.6 and 1250-3912 times that of morphine and aspirin, respectively. The analgesic effect of AAC was antagonized by naloxone, but was eliminated by reserpine. In monkeys, after AAC was injected for 92 days, no abstinence syndrome was seen after sudden AAC withdrawal or when challenged with nalorphine. (3) Huperzine A (Hup-A) is an alkaloid isolated from Huperzia serrata which was found to be a selective ChE inhibitor and could improve learning and retrieval process. Preliminary clinical studies showed that Hup-A improve short-and long-term memory in patients of cerebral arteriosclerosis with memory impairment. (4) Ranamargarin is a new tetradecapeptide isolated from the skin of the Chines frog Rana margaratae. This peptide may mainly act on NK-1 receptor.
Descritores: Medicamentos de Ervas Chinesas/farmacologia
Depressores do Sistema Nervoso Central/farmacologia
Fármacos do Sistema Nervoso Central/farmacologia
Transtornos da Memória/tratamento farmacológico
-Dados de Sequência Molecular
Sequência de Aminoácidos
Avaliação de Medicamentos
Avaliação Pré-Clínica de Medicamentos
Limites: Seres Humanos
Animais
Responsável: BR1.1 - BIREME


  4 / 21 LILACS  
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Id: biblio-951913
Autor: Ribeiro, Tatiane Bomfim; Melo, Daniela Oliveira de; Maia, Flávia de Oliveira Motta; Ribeiro, Eliane.
Título: Medication-related inpatient falls: a critical review
Fonte: Braz. J. Pharm. Sci. (Online);54(1):e17355, 2018. tab, graf.
Idioma: en.
Resumo: Abstract Falls are the second leading cause of accidental and unintentional injury deaths worldwide. Inpatient falls in hospital settings are likely to prolong the length of stay of patients in nearly 6.3 days, leading to increased hospitalization costs. The causes of fall incidents in healthcare facilities are multifactorial in nature and certain medications use could be associated with these incidents. This review seeks to critically evaluate the available literature regarding the relationship between inpatient falls and medication use. A comprehensive search was performed on MEDLINE, EMBASE and Lilacs with no time restriction. The search was filtered using English, Spanish or Portuguese languages. Our study evaluated medication use and inpatients falls that effectively happen, considering all ages and populations. An assessment of bias and quality of the studies was carried out using an adapted tool from the literature. The drugs were classified according to the Anatomic Therapeutics Chemical Code. The search strategy retrieved 563 records, among which 23 met the eligibility criteria; ninety three different pharmacological subgroups were associated with fall incidents. Our critical review suggests that the use of central nervous system drugs (including anxiolytics; hypnotics and sedatives; antipsychotics; opioids; antiepileptics and antidepressants) has a greater likelihood of causing inpatient falls. A weak relationship was found between other pharmacological subgroups, such as diuretics, cardiovascular system-related medications, and inpatient fall. Remarkably, several problems of quality were encountered with regard to the eligible studies. Among such quality problems included retrospective design, the grouping of more than one medication in the same statistical analysis, limited external validity, problems related to medication classifications and description of potential confounders.
Descritores: Acidentes por Quedas/prevenção & controle
Fármacos do Sistema Nervoso Central/farmacologia
Pacientes Internados/classificação
-Ferimentos e Lesões/classificação
Medição de Risco
Serviços de Saúde/estatística & dados numéricos
Tipo de Publ: Revisão
Responsável: BR1.1 - BIREME


  5 / 21 LILACS  
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Id: biblio-847409
Autor: Serrano, Alan Indio; Vieira, Guilherme Mello; Ferracioli, Jair Abdon; Macarini, Anna Paula; Teixeira, Mário Aurélio Aguiar.
Título: Personalidades desviantes: protocolo clínico / Deviant personalities: clinical protocol.
Fonte: Florianópolis; Santa Catarina (Estado). Secretaria da Saúde; [2014].
Idioma: pt.
Descritores: Protocolos Clínicos
Transtornos da Personalidade/diagnóstico
-Fármacos do Sistema Nervoso Central/uso terapêutico
Assistência à Saúde Mental
Transtornos da Personalidade/terapia
Padrões de Prática Médica
Limites: Seres Humanos
Responsável: BR1.1 - BIREME


  6 / 21 LILACS  
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Id: biblio-847408
Autor: Saraiva, Sônia A. Leitão; Serrano, Alan Indio; Vieira, Guilherme Mello; Ferracioli, Jair Abdon; Zepeda, Jorge Ernesto S; Rotava, Daiane S.
Título: Transtorno de estresse pós-traumático: protocolo clínico / Posttraumatic stress disorder: clinical protocol.
Fonte: Florianópolis; Santa Catarina (Estado). Secretaria da Sáude; [2015].
Idioma: pt.
Descritores: Protocolos Clínicos
Transtornos de Estresse Pós-Traumáticos/diagnóstico
-Fármacos do Sistema Nervoso Central/uso terapêutico
Assistência à Saúde Mental
Padrões de Prática Médica
Transtornos de Estresse Pós-Traumáticos/terapia
Limites: Seres Humanos
Responsável: BR1.1 - BIREME


  7 / 21 LILACS  
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Id: biblio-847407
Autor: Saraiva, Sônia A. Leitão; Serrano, Alan Indio; Zepeda, Jorge Ernesto S; Vieira, Guilherme Mello; Ferracioli, Jair Abdon; Rotava, Daiane S; Macarini, Anna Paula.
Título: Transtorno de pânico: protocolo clínico / Panic disorder: clinical protocol.
Fonte: Florianópolis; Santa Catarina (Estado). Secretaria da Saúde; [2014].
Idioma: pt.
Descritores: Protocolos Clínicos
Transtorno de Pânico/diagnóstico
-Agorafobia/patologia
Fármacos do Sistema Nervoso Central/uso terapêutico
Assistência à Saúde Mental
Transtorno de Pânico/terapia
Transtornos Fóbicos/patologia
Padrões de Prática Médica
Limites: Seres Humanos
Responsável: BR1.1 - BIREME


  8 / 21 LILACS  
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Id: biblio-847406
Autor: Serrano, Alan Indio; Vieira, Guilherme Mello; Rotava, Daiane S; Knoll, Rosalie Kupka; Ferracioli, Jair Abdon.
Título: Risco de suicídio: protocolo clínico / Risk of suicide: clinical protocol.
Fonte: Florianópolis; Santa Catarina (Estado). Secretaria da Saúde; [2014].
Idioma: pt.
Descritores: Protocolos Clínicos
Transtorno Depressivo Maior/patologia
Tentativa de Suicídio/psicologia
-Fármacos do Sistema Nervoso Central/uso terapêutico
Assistência à Saúde Mental
Padrões de Prática Médica
Tentativa de Suicídio/prevenção & controle
Limites: Seres Humanos
Responsável: BR1.1 - BIREME


  9 / 21 LILACS  
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Id: biblio-847392
Autor: Vieira, Guilherme Mello; Serrano, Alan Indio; Coimbra, Lia Quaresma; Bernardo, Noêmia Liege M. da Cunha; Macarini, Anna Paula.
Título: Esquizofrenias: protocolo clínico / Schizophrenia: clinical protocol.
Fonte: Florianópolis; Santa Catarina (Estado). Secretaria da Saúde; [2015].
Idioma: pt.
Descritores: Protocolos Clínicos
Atenção Primária à Saúde/métodos
Esquizofrenia/diagnóstico
-Fármacos do Sistema Nervoso Central/uso terapêutico
Delírio/complicações
Alucinações/complicações
Padrões de Prática Médica
Esquizofrenia/tratamento farmacológico
Limites: Seres Humanos
Tipo de Publ: Guia de Prática Clínica
Responsável: BR1.1 - BIREME


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Id: lil-753994
Autor: Tsukamoto, Heloísa Freiria; Costa, Viviane de Souza Pinho; Silva Junior, Rubens Alexandre da; Pelosi, Gislaine Garcia; Marchiori, Luciana Lozza de Moraes; Vaz, Cláudia Regina Sanches; Fernandes, Karen Barros Parron.
Título: Effectiveness of a vestibular rehabilitation protocol to improve the health-related quality of life and postural balance in patients with vertigo
Fonte: Int. arch. otorhinolaryngol. (Impr.);19(3):238-247, July-Sept/2015. tab, graf.
Idioma: en.
Resumo: Introduction Dizziness can be characterized as a balance disorder that causes discomfort, leading to several functional limitations. Currently, vestibular rehabilitation has been highlighted as a possible treatment. Objective Analyze the effects of completing a vestibular rehabilitation treatment protocol on quality of life and postural balance in patients with vestibular complaints, as well as to compare these effects between the patients taking or not taking antivertigo drugs. Methods A nonrandomized controlled trial was performed with 20 patients previously diagnosed with vestibular diseases. Information regarding vertigo symptoms, quality of life as assessed through the Dizziness Handicap Inventory, visual analog scale of dizziness, and stabilometry using force platform was collected. Patients were treated for 12 weeks by a customprotocol. The sample was divided into two groups according to the use (medicated group, n = 9) or not (control group, n = 11) of antivertigo drugs. Results There was improvement in quality of life (p < 0.001) and intensity of dizziness (p = 0.003) with the intervention. An improvement of postural balance was observed through functional tests. However, no statistically significant difference was noted in stabilometry. When both groups were compared, no statistically significant differences between the variations of the variables analyzed were found in the re-evaluation session. Conclusion Quality of life and postural balance are improved with intervention. However, this improvement is not associated with pharmacologic treatment.
Descritores: Fármacos do Sistema Nervoso Central
Equilíbrio Postural
Postura
Qualidade de Vida
Sinais e Sintomas
Vertigem/reabilitação
-Brasil
Protocolos
Limites: Masculino
Feminino
Adulto
Idoso
Responsável: BR66.1 - Divisão de Biblioteca e Documentação



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