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Id: biblio-949946
Autor: Lazzarini, Rosana; Mendonça, Rodolfo Ferreira; Hafner, Mariana de Figueiredo Silva.
Título: Allergic contact dermatitis to shoes: contribution of a specific series to the diagnosis
Fonte: An. bras. dermatol;93(5):696-700, Sept.-Oct. 2018. tab.
Idioma: en.
Resumo: Abstract: Background: In our country, the Brazilian Standard Series is the most used for the etiological diagnosis of allergic contact dermatitis to shoes. However, there is no assessment of the usefulness of specific allergens for shoes. Objectives: To measure the improvement in diagnostic accuracy of allergic contact dermatitis to shoes with the use of a specific complementary series in patch testing and describe the characteristics of the affected population, such as gender, location of lesions, time of evolution, and the most common allergens. Methods: This retrospective study evaluated the results of 52 patients with suspected shoe dermatitis subjected to patch tests with the standard and specific series to quantify the gain in diagnostic accuracy. Results: Among the 52 suspected cases, 29 cases (56%) were confirmed. In 13 (45%) cases the diagnosis was determined through the specific series, which results in an 81% increase in the number of diagnoses. Study limitation: Small sample size. Conclusions: Women were more commonly affected, with a mean time for the final diagnosis of 45 months, and the most common localization was the dorsum of the feet. There was an increase in diagnostic accuracy with the introduction of new haptens in the patch test of patients with suspected shoes dermatitis.
Descritores: Sapatos/efeitos adversos
Alérgenos/análise
Dermatite Alérgica de Contato/diagnóstico
Dermatoses do Pé/diagnóstico
-Brasil
Testes do Emplastro
Alérgenos/efeitos adversos
Estudos Retrospectivos
Dermatite Alérgica de Contato/etiologia
Dermatoses do Pé/etiologia
Limites: Seres Humanos
Masculino
Feminino
Meia-Idade
Responsável: BR1.1 - BIREME


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Id: biblio-1038283
Autor: Hafner, Mariana de Figueiredo Silva; Munhoz, Sandy Daniele Germano; Jeldes, Ariel Garcia; Lazzarini, Rosana.
Título: Positive results of patch tests with fragrance markers: analysis of a 15-year period at a Brazilian dermatology center
Fonte: An. bras. dermatol;93(6):910-912, Nov.-Dec. 2018.
Idioma: en.
Resumo: Abstract: Fragrances may cause allergic contact dermatitis. Data on patients who were patch tested, between 2000 and 2015, with fragrance allergens included in the Brazilian baseline series (balsam of Peru, colophony and fragrance mix I), were collected and analyzed. Of these patients, 258 (13.8%) were positive for fragrance markers, 9.8% being positive for fragrance mix I. Among these 258 there was a predominance of women in their 40s, with hand eczema. The frequency of sensitization to fragrances, as well as the epidemiological profile, was supported by the literature. Fragrance mix I was the main marker. It is important to expand the fragrance markers used in the Brazilian baseline series of patch tests.
Descritores: Perfumes/efeitos adversos
Dermatite Alérgica de Contato/diagnóstico
-Testes do Emplastro/métodos
Dermatite Alérgica de Contato/etiologia
Limites: Seres Humanos
Masculino
Feminino
Meia-Idade
Responsável: BR1.1 - BIREME


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Id: biblio-973627
Autor: Corrêa-Fissmer, Mariane; Dalazen, Cintia Camila; Ferreira, Bárbara Piacentini; Iser, Betine Pinto Moehlecke.
Título: Assessment of patch test results carried out during ten years in a city in southern Brazil
Fonte: An. bras. dermatol;93(6):807-812, Nov.-Dec. 2018. tab.
Idioma: en.
Resumo: Abstract: Background: Contact dermatitis affects up to 20% of the population. Patch testing for contact allergy may be needed to confirm the diagnosis. Objectives: To describe and discuss the results of patch tests performed in a city in southern Brazil. Methods: A cross-sectional analysis was performed on all skin test results over ten years. Variables such as gender, age at the time of testing, and test results were evaluated. Triggering factors, duration of complain, and previous medications used related to the clinical history were retrieved for some patients by reviewing their medical records. Results: The sample was composed of 539 patch tests, of which 411 (76.2%) were from women. The age of the tested subjects ranged from 5 to 87 years. The prevalence of positive reactions in the patch tests was 391 (72.5%). The most prevalent positive reaction was to nickel sulfate (196; 36.4%), which had statistical significance when associated with female gender (p<0,001). Study limitations: Database obtained through secondary sources (the reports of the exams and the medical records), occurring the incomplete registration of some information. Conclusions: Data analysis at the local level is important to define preventive policies.
Descritores: Dermatite Alérgica de Contato/diagnóstico
-Brasil/epidemiologia
Testes do Emplastro
Prevalência
Estudos Transversais
Dermatite Alérgica de Contato/epidemiologia
Limites: Seres Humanos
Masculino
Feminino
Pré-Escolar
Criança
Adolescente
Adulto
Meia-Idade
Idoso
Idoso de 80 Anos ou mais
Adulto Jovem
Responsável: BR1.1 - BIREME


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Melo, Maria das Graças Mota
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Id: biblio-1001140
Autor: Melo, Maria das Graças Mota; Villarinho, Ana Luiza Castro Fernandes; Leite, Iuri da Costa.
Título: Sociodemographic and clinical profile of patients with occupational contact dermatitis seen at a work-related dermatology service, 2000 - 2014
Fonte: An. bras. dermatol;94(2):147-156, Mar.-Apr. 2019. tab, graf.
Idioma: en.
Resumo: Abstract: BACKGROUND: Occupational dermatoses are common, especially contact dermatitis. Epidemiological studies on these dermatoses are scarce in Brazil and they are necessary as part of the public policy to protect workers' health. OBJECTIVES: To identify sociodemographic and clinical profile of patients with occupational contact dermatitis seen between 2000 and 2014 at an occupational dermatology service. METHODS: It is a cross-sectional and retrospective study, based on information obtained from the service's database. RESULTS: Of 560 patients with conclusive patch test, 289 (46.9%) presented occupational dermatoses and 213 occupational contact dermatitis with predominance of the allergic type in relation to the irritative type (149:64 respectively). The odds of occupational dermatoses were higher among men and lower among patients aged 50 years or older and with higher level of education. Regarding the possibility of presenting occupational allergic contact dermatitis, only the gender variable was statistically significant. The professions most seen were cleaners, construction workers, painters, mechanics/metallurgists and cooks. The commonest allergens were nickel sulfate, potassium dichromate, cobalt chloride, carba-mix and formaldehyde. STUDY LIMITATIONS: The main limitations of this study are the fact that it was carried out in a tertiary service of occupational dermatoses and the lack of access to some allergens outside the patch test baseline series. CONCLUSIONS: It was possible to identify the sociodemographic and clinical profile of patients with suspected occupational contact dermatitis seen at the Service, beyond the professional groups and allergens related to a high risk of occupational contact dermatitis in this population.
Descritores: Exposição Ocupacional/estatística & dados numéricos
Dermatite Alérgica de Contato/epidemiologia
Dermatite Ocupacional/epidemiologia
-Dicromato de Potássio/efeitos adversos
Fatores Socioeconômicos
Brasil/epidemiologia
Testes do Emplastro/estatística & dados numéricos
Cáusticos/efeitos adversos
Indústria da Construção
Fatores Sexuais
Estudos Transversais
Estudos Retrospectivos
Exposição Ocupacional/efeitos adversos
Fatores Etários
Dermatite Irritante/etiologia
Dermatite Irritante/epidemiologia
Dermatite Alérgica de Contato/etiologia
Dermatite Ocupacional/etiologia
Escolaridade
Dermatoses da Mão/induzido quimicamente
Dermatoses da Mão/epidemiologia
Irritantes/efeitos adversos
Níquel/efeitos adversos
Limites: Seres Humanos
Masculino
Feminino
Adolescente
Adulto
Meia-Idade
Adulto Jovem
Responsável: BR1.1 - BIREME


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Id: biblio-827762
Autor: Sousa, Aline Soares de; Cardoso, José Carlos; Gouveia, Miguel Pinto; Gameiro, Ana Rita; Teixeira, Vera Barreto; Gonçalo, Maria.
Título: Fixed drug eruption by etoricoxib confirmed by patch test
Fonte: An. bras. dermatol;91(5):652-654, Sept.-Oct. 2016. graf.
Idioma: en.
Resumo: Abstract: Non-steroidal, anti-inflammatory drugs, followed by antibiotics, are the main causes of fixed drug eruption. They provoke one or several round erythematous or bullous lesions that recur in the same place after taking the causative medication. A positive patch test on residual, lesional skin can replace satisfactorily oral reintroduction. We describe the case of a 74-year-old woman with numerous, rounded, erythematous lesions on the trunk and recurrent blistering on the fifth right-hand finger, which developed a few hours after taking etoricoxib. Lesional patch testing with etoricoxib was positive and reproduced the typical pattern of a fixed drug eruption upon histopathology. We emphasize the specific reactivity of the etoricoxib patch test, and the capacity to reproduce the histologic pattern of the reaction.
Descritores: Piridinas/efeitos adversos
Sulfonas/efeitos adversos
Testes do Emplastro/métodos
Erupção por Droga/etiologia
Inibidores de Ciclo-Oxigenase 2/efeitos adversos
-Erupção por Droga/patologia
Limites: Seres Humanos
Feminino
Idoso
Tipo de Publ: Relatos de Casos
Responsável: BR1.1 - BIREME


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Id: lil-781370
Autor: Yoshimura, Fernanda Cortinhas; Cunha, Victor do Espirito Santo; Hahnstadt, Ruppert Ludwig; Pires, Mário Cezar.
Título: Evaluation of dental material series from patients with dental prostheses and suspicion of delayed hypersensitivity
Fonte: An. bras. dermatol;91(2):141-148, Mar.-Apr. 2016. tab.
Idioma: en.
Resumo: Abstract: BACKGROUND: Patients with oral sensitivity are common in our practice. Allergic contact dermatitis is one of the most frequent etiologies. OBJECTIVES: Evaluate oral contact dermatitis using the Brazilian standard series and complementary dental series in patients using dental prostheses, with or without oral complaints. Determine specific dental Brazilian series. METHODS: Patients using dental prostheses with or without oral complaints realized patch tests. Brazilian standard series and complementary dental series were used according to ICDRG recommendations. The results were analysed according to age, sex, race, atopic conditions and symptoms associated. RESULTS: From 54 patients tested, 34 (63%) were positive at least to one substance. Nineteen had oral complaints, such as burning mouth, itch or oral erythema. There was no association between atopic condition and tests results. Without the oral series, just 23(42,6%) patients had a positive result. Using the Brazilian standard series with the complementary dental series we improved the positivity of the patch test to 47%. CONCLUSION: In patients using prostheses and with oral complaints, patch tests with Brazilian standard series with complementary dental series improve the tests positivity.
Descritores: Testes do Emplastro/métodos
Dermatite Alérgica de Contato/diagnóstico
Dermatite Alérgica de Contato/etiologia
Prótese Dentária/efeitos adversos
Materiais Dentários/efeitos adversos
-Fatores de Tempo
Brasil
Testes do Emplastro/normas
Alérgenos
Valor Preditivo dos Testes
Reprodutibilidade dos Testes
Limites: Seres Humanos
Masculino
Feminino
Adulto
Meia-Idade
Idoso
Idoso de 80 Anos ou mais
Tipo de Publ: Estudos de Avaliação
Responsável: BR1.1 - BIREME


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Id: lil-781352
Autor: Chen, Hao; Liu, Guanghui; Huang, Nan; Li, Wenjing; Dong, Xiang; Zhu, Rongfei.
Título: Incidence of allergic contact sensitization in central Chinese subjects with chronic urticaria
Fonte: An. bras. dermatol;91(2):168-172, Mar.-Apr. 2016. tab, graf.
Idioma: en.
Resumo: Abstract BACKGROUND: Chronic urticaria (CU) can be provoked by a wide variety of causes. Some studies suggest contact sensitization may play a role in the disease. OBJECTIVE: To investigate the incidence and distribution characteristics of allergic contact sensitization in central Chinese subjects with CU, and assess contact allergen avoidance measures in managing CU. METHODS: Patch tests were performed, following the recommended standard procedure, with 20 selected allergens, in line with the European baseline series. All subjects with positive results were prescribed appropriate avoidance measures for the sensitizing substances, while subjects with negative results served as the control group. CU severity was assessed daily from week1 to week4 and for each subject, applying the Urticaria Activity Score. RESULTS: 42.9% (233/543) of subjects with CU showed positive reactions to one or more contact allergen(s). Potassium dichromate, benzene mix and carba mix were more common in male patients, while nickel sulfate was more frequent in females. The positive rates for different allergens varied with age and occupation. The median (interquartile range) severity scores at week 1 were 20 (14-21) and 15 (14-27) for the allergen avoidance group and control group, respectively (P>0.05); and 12 (7-15) and 14 (12-17) at week 4 (P<0.001). CONCLUSION: The incidence of allergic contact sensitization in CU patients was high, and appropriate contact allergen avoidance measures benefitted CU management. Contact allergens may play a role in the pathogenic mechanism of CU and patch tests are an option for CU patients.
Descritores: Urticária/complicações
Urticária/epidemiologia
Alérgenos/imunologia
Dermatite Alérgica de Contato/etiologia
Dermatite Alérgica de Contato/epidemiologia
-Índice de Gravidade de Doença
Testes do Emplastro
China/epidemiologia
Doença Crônica
Incidência
Distribuição por Sexo
Distribuição por Idade
Estatísticas não Paramétricas
Ocupações/estatística & dados numéricos
Limites: Seres Humanos
Masculino
Feminino
Pré-Escolar
Criança
Adolescente
Adulto
Meia-Idade
Idoso
Idoso de 80 Anos ou mais
Adulto Jovem
Responsável: BR1.1 - BIREME


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Id: biblio-868715
Autor: Jurgens, Carola; Pizarro, Romina; Nardelli, Andrea; Consigli, Carlos.
Título: Níquel y prótesis: provocador en potencia de reacciones sistémicas / Nickel and prosthesis provocative potential of systemic reactions
Fonte: Alerg. inmunol. clin;35(3-4):16-21, 2015. tab.
Idioma: es.
Descritores: Cobalto
Cobalto/efeitos adversos
Cromo
Cromo/efeitos adversos
Dermatite de Contato
Níquel
Níquel/efeitos adversos
Testes do Emplastro
Próteses e Implantes/efeitos adversos
Limites: Seres Humanos
Masculino
Feminino
Responsável: AR32.1 - Biblioteca Prof. Dr. J. M. Allende


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Id: biblio-868710
Autor: Colazo Lazcano, MS; Campana, R; Serra Criscuolo, MT.
Título: Dermatitis alérgica de contacto por cosméticos en un consultorio alergoinmunologico / Allergic dermatitis of contact by cosmetics in a alego-immunological doctor`s office
Fonte: Alerg. inmunol. clin;34(1-2):12-16, 2014. tab, graf.
Idioma: es.
Resumo: La dermatitis de contacto (DC) es una respuesta inflamatoria de la piel, como resultado del contacto de la misma con múltiples factores externos, frecuentemente contenidos en cosméticos. Las pruebas del parche son el pilar diagnostico. Se evaluó la prevalencia de la dermatitis alérgica de contacto por cosméticos, determinando las relaciones epidemiológicas como: edad, sexo, localización, ocupación y sensibilización. El 70% de los pacientes estudiados fueron DAC y el 30% fuerondermatitis irritativas por contacto (DIC). El 57% de las dermatitis alérgicas estaban asociadas a cosméticos,predominando en el sexo femenino.

Contact dermatitis (AD) is an inflammatory response of the skinas a result of contact with multiple external factors, often containedin cosmetics. Patch tests are the diagnostic pillar. Prevalence of allergic contact dermatitis to cosmetics was evaluatedby determining the epidemiological relationships as age, sex, location, occupation and awareness.70% of the patients studied were DAC and 30% were irritant contact dermatitis (ICD).57% of allergic dermatitis were associated with cosmetics, predominantly in females.
Descritores: Dermatite Alérgica de Contato/diagnóstico
Dermatite Alérgica de Contato/epidemiologia
Dermatite Alérgica de Contato/imunologia
Dermatite Irritante/diagnóstico
Dermatite Irritante/imunologia
Testes do Emplastro/estatística & dados numéricos
Testes do Emplastro/métodos
Limites: Seres Humanos
Masculino
Feminino
Responsável: AR32.1 - Biblioteca Prof. Dr. J. M. Allende


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Id: biblio-835955
Autor: Gallego G, Consuelo; Awad R, Perla; Cárdenas D, Consuelo.
Título: Test de Parche como método diagnóstico de las reacciones adversas a medicamentos / Patch test as a diagnostic method for adverse drug reactions
Fonte: Rev. chil. dermatol;30(2):216-222, 2014. tab.
Idioma: es.
Resumo: Las reacciones adversas a medicamentos (RAM) son un motivo frecuente de consulta en la práctica dermatológica. La hipersensibilidad a fármacos es una causa común de RAM, y es de gran relevancia confirmar este mecanismo para que el paciente evite futuras exposiciones. El test de parche tiene un rol relevante en el proceso diagnóstico de las reacciones de hipersensibilidad no inmediatas, otros test como la intradermorreacción o el test de provocación son más invasivos o de alto riesgo, y los exámenes in vitro para reacciones tardías no se encuentran fácilmente disponibles. El problema es que existe escasa estandarización del procedimiento y el valor predictivo del examen es incierto. En esta revisión exponemos la mejor evidencia disponible, lo que permitirá al especialista decidir cuándo hacer este examen y cómo interpretar sus resultados.

Adverse drugs reactions (ADR) are a frequent diagnosis in dermatological practice. Drug hypersensitivity is a common ADR etiology, and it is greatly relevant to confirm this mechanism to avoid future exposures of the patient to the culprit drug. Patch test has an outstanding role in non-immediate hypersensitivity reactions diagnosis process, other tests like intradermal reaction or provocation test are more aggressive or implies more risk, and in-vitro test for non-inmediate reactions are not easily available. One of the main problems of patch test is the lack of standarization of the procedure and the uncertain predictive value. In this review is exposed the best evidence available, so the specialist could decide when to do the test and how interpret its results.
Descritores: Efeitos Colaterais e Reações Adversas Relacionados a Medicamentos
Hipersensibilidade/diagnóstico
Testes do Emplastro/métodos
-Erupção por Droga/etiologia
Testes Cutâneos/métodos
Limites: Seres Humanos
Responsável: CL1.1 - Biblioteca Central



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