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Id: biblio-1090672
Autor: Bucchi, Cristina; de-Anta, Josep Maria; Manzanares-Céspedes, María Cristina.
Título: Micro-computed tomographic analysis of apical foramen enlargement of mature teeth: a cadaveric study / Análisis mediante micro-CT del ensanchamiento del foramen apical de dientes maduros: un estudio cadavérico
Fonte: Int. j. odontostomatol. (Print);14(2):177-182, June 2020. tab, graf.
Idioma: en.
Resumo: Revitalization procedures have been extensively studied during the last decade and offers several advantages over root canal treatment, such as the recovery of the natural immune system. Mature teeth have a small apical foramen diameter (AFD), which could impair the ingrowth of tissue into the root canal. We analysed three methods for apical foramen enlargement by instrumentation in in situ human teeth and evaluated the damage over hard tissues produced by the techniques. Tooth length (TL), defined as the length from the most coronal part of the crown to the point at which the file abandons the root canal, was calculated. Forty-four in situ teeth were randomized: Group I: instrumentation 0.5 mm coronal to TL; Group II: at TL level; Group III: 0.5 mm beyond TL. Teeth were instrumented up to K-file #80. The mandibles were scanned in a micro-CT device before and after treatment. Group I: Only 20 % of teeth presented an enlarged AFD, with augmentation of 0.09 mm. No damage to hard tissues was observed. Group II: 71.4 % of the teeth presented an enlarged AFD with augmentation of 0.42 mm. 35.7 % presented damage to periapical tissues. Group III: 86.7 % presented an enlarged AFD with augmentation of 0.43 mm. 46.7 % presented damage to periapical tissues. All groups presented similar prevalence of teeth with dentine thickness less than 1mm. All mandibular incisors presented areas of thickness less than 1mm. Instrumentation 0.5 mm beyond TL is the most effective technique.

La revitalización de dientes necróticos ha sido ampliamente estudiada durante la última década y ofrece varias ventajas sobre la endodoncia convencional, tal como la recuperación del sistema inmunitario natural del diente. Los dientes maduros tienen un diámetro de foramen apical (FA) pequeño, lo que podría afectar el crecimiento de tejido en el conducto. Se evaluaron tres métodos para la ampliación del foramen apical en dientes humanos in situ y se evaluó el daño sobre los tejidos duros producidos por las técnicas. Mediante radiografía periapical se calculó la longitud del diente (TL), definida como la longitud desde la parte más coronal de la corona hasta el punto en que la lima abandonó el conducto radicular. En el estudio fueron aleatorizados 44 dientes in situ: Grupo I: instrumentación 0,5 mm coronal a TL; Grupo II: a nivel TL; Grupo III: 0,5 mm más allá de TL. Los dientes fueron instrumentados hasta la lima K #80. Las mandíbulas se escanearon en un dispositivo de microCT antes y después del tratamiento. Grupo I: solo el 20 % de los dientes presentaron un diámetro de FA ensanchado, con un aumento de 0,09 mm. No se observó daño a los tejidos duros. Grupo II: el 71,4 % de los dientes presentaban un FA ensanchado con un aumento de 0,42 mm. El 35,7 % presentó daño a los tejidos periapicales. Grupo III: el 86,7 % presentó un FA ensanchado con un aumento de 0,43 mm. El 46,7 % presentó daño a los tejidos periapicales. Todos los grupos presentaron una prevalencia similar de dientes con un espesor de dentina inferior a 1mm. Todos los incisivos mandibulares presentaban áreas de grosor inferior a 1mm. La instrumentación 0,5 mm más allá de TL es la técnica más efectiva, aunque se debe tener especial consideración en aspectos como el debilitamiento de la estructura dentaria.
Descritores: Dente/diagnóstico por imagem
Ápice Dentário/diagnóstico por imagem
Microtomografia por Raio-X
Endodontia Regenerativa
-Dente/anatomia & histologia
Cadáver
Ápice Dentário/anatomia & histologia
Limites: Humanos
Responsável: CL1.1 - Biblioteca Central


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Id: biblio-886817
Autor: PAULINI, FERNANDA; CHAVES, SACHA B; RÔLO, JOSÉ LUIZ J P; AZEVEDO, RICARDO B DE; LUCCI, CAROLINA M.
Título: Evaluation of ovarian structures using computerized microtomography
Fonte: An. acad. bras. ciênc;89(3,supl):2131-2139, 2017. graf.
Idioma: en.
Resumo: ABSTRACT Visualization and clear understanding of the ovarian structures are important in determining the stage of oestrus, helping to diagnose several pathologies and supporting advances in reproductive technologies. In this research, computerized microtomography (microCT) was used to explore and characterize the ovarian structure of seven mammalian species. Ovaries of rats, female dog, queens, cows, mares, sows and a female donkey were used. After microCT scanning, the same samples were prepared for histologic evaluation, used here as a validation criterion. It was possible to distinguish regions of the cortex and medulla, visualize the morphology and distribution of blood vessels, clearly observe corpus luteum and antral follicles, and visualize oocytes inside some antral follicles. This is the first report using microCT to explore and compare ovarian structures in several domestic mammals. MicroCT revealed great potential for the evaluation of ovarian structures. This research open prospects for the use of computerized tomography (CT) as a non-invasive approach to studying ovarian structures in live animals, which may be especially attractive for scientific study of development of ovarian structures and/or ovarian pathologies in small animals' models.
Descritores: Microtomografia por Raio-X/métodos
Folículo Ovariano/anatomia & histologia
-Suínos
Bovinos
Imageamento Tridimensional
Cavalos
Limites: Animais
Feminino
Cães
Ratos
Responsável: BR1.1 - BIREME


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Id: biblio-1012354
Autor: Palombella, Andrew S; Wilson, Timothy D; Fernandes, Atson C. S; Galil, Khadry A.
Título: Three-dimensional micro CT derived morphology of the condylus mandibulae in older adults: implications for clinical dentistry / Micro tomografía computarizada tridimensional derivada de la morfología del cóndilo de la mandíbula en adultos mayores: implicaciones para la odontología clínica
Fonte: Int. j. morphol;37(3):787-791, Sept. 2019. tab, graf.
Idioma: en.
Resumo: Temporomandibular disorder (TMD) is a multi-etiologic disability, accompanied by a wide range of symptoms, requiring a variety of therapies, with TMJ reconstruction considered the most severe. TMJ surgery is associated with many morbidities and limitations, especially in the elderly. Previous studies have determined the shape and dimensions of the Condylus mandibulae in children and adults, but a range of measurements in the elderly population has yet to be created. This study aims to establish a range of measurements and the morphology of the Condylus mandibulae in an older population using micro CT. 14 cadaveric Condylus mandibulaes (8 male, 6 female; average age, 83±8.6) were scanned with microCT and measured using Amira 4.1.1 modeling software. The anteroposterior length (LAP), mediolateral width (WML) and height (H) of each Condylus mandibulae was measured from 5 equidistant slices in the coronal, sagittal and axial planes. Additionally, each Condylus mandibulae was measured at its greatest anteroposterior length, mediolateral width and height using digital callipers on the cadaveric specimen. This study is the first to accurately describe the morphology of the Condylus mandibulae in an elderly population. The length and width measurements of digital calliper (10.51 ± 0.87; 18.33 ± 2.35) and corresponding micro-CT (11.46 ± 1.60; 17.62 ± 2.05) both showed high consistency and reliability. Our findings lay the foundation for the creation of an off-the-shelf Condylus mandibulae prosthesis or anatomically shaped Condylus mandibulae scaffold for elderly patients.

El trastorno temporomandibular (TTM) es una discapacidad multi-etiológica, acompañada por una amplia gama de síntomas, que requieren una variedad de terapias, entre las cuales la reconstrucción de la articulación temporomandibular (ATM) es considerada una de las terapias más graves. La cirugía de la ATM se asocia con muchas morbilidades y limitaciones, especialmente en adultos mayores. Estudios previos han determinado la forma y las dimensiones del cóndilo de la mandíbula en niños y adultos, no obstante aún no se han identificado estas mediciones en una población de adultos mayores. Este estudio tiene como objetivo establecer un rango de mediciones y la morfología del cóndilo de la mandíbula en una población de adultos mayores mediante microtomografía computarizada (microCT). Se escanearon, con microCT, 14 mandíbulas cadavéricas (8 hombres, 6 mujeres; edad promedio: 83 ± 8,6 años), y se realizaron mediciones utilizando el software de modelado Amira 4.1.1. De cada cóndilo de la mandíbula se midió: longitud anteroposterior (LAP), ancho mediolateral (AML) y altura (A), a partir de 5 cortes equidistantes en los planos coronal, sagital y axial. Además, también se utilizaron calibradores digitales para realizar estas mismas mediciones. Este estudio es el primero en describir con precisión la morfología del cóndilo de la mandíbula en una población de adultos mayores. Las medidas de longitud y anchura del calibrador digital (10,51 ± 0,87; 18,33 ± 2,35) y el micro-CT correspondiente (11,46 ± 1,60; 17,62 ± 2,05) mostraron una alta consistencia y confiabilidad. Nuestros hallazgos sientan las bases para la creación de una prótesis de cóndilo de la mandíbula o un andamio condilar de forma anatómica para pacientes de edad avanzada.
Descritores: Microtomografia por Raio-X
Côndilo Mandibular/diagnóstico por imagem
-Cadáver
Imageamento Tridimensional
Côndilo Mandibular/anatomia & histologia
Limites: Humanos
Masculino
Feminino
Idoso
Idoso de 80 Anos ou mais
Responsável: CL1.1 - Biblioteca Central


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Id: biblio-1103880
Autor: Guimarães, Alexandre de Freitas Caetano; Pinto, Karem Paula; Ferreira, Cláudio Malizia Alves; Lima, Carolina Oliveira de; Sassone, Luciana Moura; Silva, Emmanuel João Nogueira Leal da.
Título: Efeito do consumo de álcool no desenvolvimento de lesão periapical induzida em ratos: uma análise microtomográfica / The Effect of Alcohol Consumption on the Development of Periapical Lesion Induced in Rats: a Micro-CT Analysis
Fonte: Rev. bras. odontol;77(1):1-5, jan. 2020. ilus, tab.
Idioma: en.
Resumo: Objetivo: O objetivo deste estudo foi avaliar a influência do consumo crônico de álcool no aumento da destruição óssea periapical em ratos. Material e métodos: Foram selecionados 12 ratos machos da linhagem Wistar, aleatoriamente divididos nos grupos controle e álcool (n=6). Os ratos do grupo álcool foram submetidos à auto-administração de solução alcoólica contendo 25% de álcool puro. O grupo controle recebeu apenas água filtrada durante o estudo. Após as 5 semanas de adaptação do grupo álcool, todos os ratos foram anestesiados e a polpa dos seus primeiros molares inferiores esquerdos foi exposta à cavidade oral para indução da lesão periapical. Após 28 dias de exposição pulpar, os ratos foram sacrificados por sobredose de anestesia, e suas mandíbulas foram removidas e seccionadas para avaliação microtomográfica. As hemimandíbulas esquerdas foram fixadas e escaneadas no microtomógrafo SkyScan 1173 (Bruker, Kontich, Belgium). O tamanho da lesão periradicular foi medido a partir das imagens de microtomografia computadorizada (micro-CT), onde foram calculados a área de superfície e o volume da lesão. Também foram avaliadas a taxa percentual de ganho de peso e a ingestão de sólidos/líquidos dos grupos. Os dados foram estatisticamente analisados utilizando o teste t de Student (p<0,05). Resultados: Os animais do grupo controle tiveram uma maior taxa percentual de ganho de peso corporal e de ingestão tanto de sólidos como de líquidos (p<0,05). As lesões periapicais apresentaram maior volume e maior área nos animais do grupo álcool, em comparação ao grupo controle (p<0,05). Conclusão: O consumo crônico de álcool contribuiu para o aumento da destruição óssea periapical em casos de periodontite apical.

Objective: the aim of this study was to evaluate the influence of alcohol consumption on the increase of periapical bone destruction in rats. Material and Methods: the sample included 12 Wistar male rats, randomly assigned into a control group and an alcohol group (n=6). Rats in the alcohol group were submitted to self-administration of a 25% pure alcoholic solution. The control group received only filtered water throughout the study. After 5 weeks of adaptation to the alcohol dose, all animals were anesthetized and the pulps of their mandibular left first molar were exposed to the oral cavity to induce periapical lesion. Twenty-eight days after the pulp exposure, those rats were euthanized due to overdose of anesthesia and their mandibles were removed and sectioned to obtain a micro-computed tomographic (micro-CT) scan. The rats' left hemimandibles were fixed and scanned on the SkyScan 1173 (Bruker, Konitch, Belgium) microtomograph. The size of the periradicular lesions was measured from the images obtained on the micro-CT and the surface area and volume were calculated. It was also evaluated the weight gain rate and the ingestion of solid/liquid of both groups. Data were analyzed by the Student's t-test (p<0.05). Results: the control group showed higher rates of weight gain and ingested more solid and liquid than the alcohol group (p<0.05). Periapical lesions found in the alcohol group had higher volume and surface area than the ones of the control group (p<0.05). Conclusion: the chronic consumption of alcohol contributed to the increase of periapical bone destruction in cases of apical periodontitis
Descritores: Periodontite
Alcoolismo
-Microtomografia por Raio-X
Responsável: BR485.1 - Biblioteca Mário Badan


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Marcantonio, Rosemary Adriana Chiérice
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Id: biblio-1014407
Autor: ARONI, Mauricio Andrés Tinajero; COSTA NETO, Paulo Firmino da; OLIVEIRA, Guilherme José Pimentel Lopes de; MARCANTONIO, Rosemary Adriana Chiérici; MARCANTONIO JUNIOR, Elcio.
Título: Bone repair induced by different bone graft substitutes in critical-sized defects in rat calvaria / Avaliação do reparo ósseo induzido por diferentes substitutos ósseos em modelo de defeito crítico de calvária de ratos
Fonte: Rev. odontol. UNESP (Online);48:e20190041, 2019. tab, ilus.
Idioma: en.
Resumo: Abstract Introduction The use of bone substitutes in grafting procedures as an alternative of the use of autogenous bone graft has been indicated, however, the direct comparison between these biomaterials has been little explored. Objective To evaluate the effect of different osteoconductive bone substitutes on the bone repair in critical-sized defects (CSDs) in rat calvaria. Material and method One CSD with an 8 mm diameter was made in each of the 40 rats used in this study. The animals were randomly allocated into 5 groups (n=8), according to the type of bone substitute used to fill the CSD: COA (Coagulum); AUT (autogenous bone); DBB (deproteinized bovine bone graft); HA/TCP (biphasic ceramic composed of hydroxyapatite and β-phosphate tricalcium); and TCP (β-phosphate tricalcium). A microtomographic analysis was performed to evaluate the remaining defect linear length (DLL) of the CSD and the volume of the mineralized tissues (MT) within the CSD at 3, 7, 15 and 30 days after the surgical procedure. In addition, a histometric analysis was performed to evaluate the composition of the repaired bone tissue (% Bone and % Biomaterial) at the 30-day period. Result It was shown that the COA had the lowest DLL and MT within the CSD. In addition, the COA presented the highest % of bone in CSD. The DBB had a higher MT and a higher % of bone substitute particles in the CSD than the AUT and TCP groups. The DBB and AUT groups presented higher % of bone in the CSD than the TCP group. Conclusion The use of the DBB promoted a better pattern of bone volume gain and formation compared to TCP and HA / TCP but was biologically inferior to the AUT.

Resumo Introdução A utilização de substitutos ósseos em procedimentos de enxertia de forma alternativa ao uso do osso autógeno tem sido indicada, entretanto a comparação direta entre esses biomateriais tem sido pouco explorada. Objetivo Avaliar o efeito de diferentes biomateriais osteocondutores sobre o reparo de defeitos críticos em calvárias (DCC) de ratos. Material e método Foram utilizados 40 ratos que foram submetidos a confecção de um DCC com 8 mm de diâmetro. Os animais foram aleatoriamente divididos em 5 grupos com 8 animais, de acordo com o tipo de biomaterial utilizado para preencher os DCC: Grupo COA (coágulo); Grupo AUT (osso autógeno); Grupo OBD (osso bovino desproteinizado); Grupo HA/ TCP (cerâmica bifásica composta de hidroxiapatita e β fosfato tricálcio); Grupo TCP (β fosfato tricálcio). Foram executadas análise microtomográfica para avaliação do comprimento linear remanescente (DLL) do DCC e o volume dos tecidos mineralizados (MT) dentro do DCC nos períodos de 3, 7, 15 e 30 dias após cirurgia. Adicionalmente, foi executado análise histométrica para avaliar a composição do tecido ósseo reparado (% Osso e % Biomaterial) no período de 30 dias. Resultado O grupo COA apresentou o menor DLL e MT dentro do DCC e maior % osso do que os outros grupos. O grupo OBD apresentou maior volume de tecidos mineralizados e maior % biomaterial do que o grupo os grupos AUT e TCP. Os grupos OBD e AUT apresentaram maior % osso que o grupo TCP. Conclusão O OBD promoveu melhor padrão de aumento de disponibilidade óssea e qualidade do osso reparado em comparação ao TCP e HA/TCP, porém biologicamente inferior ao grupo AUT.
Descritores: Regeneração Óssea
Substitutos Ósseos
Microtomografia por Raio-X
-Ratos
Crânio
Limites: Animais
Masculino
Ratos
Responsável: BR39.2 - Biblioteca Professora Maria Dilma de Oliveira Gonçalves


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Id: biblio-1099186
Autor: TORRES, Fernanda Ferrari Esteves; GUERREIRO-TANOMARU, Juliane Maria; PINTO, Jader Camilo; BONETTI-FILHO, Idomeo; TANOMARU-FILHO, Mário.
Título: Evaluation of flow and filling of root canal sealers using different methodologies / Avaliação do escoamento e preenchimento de cimentos obturadores utilizando diferentes metodologias
Fonte: Rev. odontol. UNESP (Online);48:e20190112, 2019. tab, ilus.
Idioma: en.
Projeto: CAPES; . FAPESP.
Resumo: Abstract Introduction Flow and filling ability of root canal sealers are indispensable for hermetic sealing of the root canal. Micro-computed tomography (micro-CT) can be used as a complementary methodology to evaluate such properties. Objective To evaluate the flow and filling ability of AH Plus, Endofill and Sealapex by conventional methodology and micro-CT. Material and method The flow of the sealers was analyzed according to ISO 6876/2012 and complemented by the area evaluation. Glass plates were manufactured with diameters of 1×1×2 mm and 1×1×1 mm (length, width and height), with a central cavity and four grooves in the horizontal and vertical directions. Each material was placed in the central cavity. Another glass plate and a metal weight were placed on the cement and kept for 10 minutes. The glass plate/sealer set was scanned using micro-CT. The flow was calculated by linear measurement of the material in the grooves. The central filling (mm3) was calculated in the central cavity and the lateral filling was measured up to 2 mm from the central cavity. Data were submitted to ANOVA/Tukey tests (α=0.05). Result All evaluated sealers presented flow according to ISO 6876 standards. The materials showed central cavity filling capacity higher than 80% and lateral filling greater than 75%. There was no difference in flow (mm and mm2) and in the filling ability (mm3) provided by the materials (p>0.05). Conclusion All evaluated root canal sealers showed adequate flow and filling capacity, suggesting their clinical application.

Resumo Introdução Escoamento e capacidade de preenchimento de cimentos obturadores são indispensáveis para um selamento hermético do canal radicular. Microtomografia computadorizada (micro-CT) pode ser utilizada como uma metodologia complementar para avaliação de tais propriedades. Objetivo Avaliar escoamento e capacidade de preenchimento de AH Plus, Endofill e Sealapex, por meio de metodologia convencional e micro-CT. Material e método O escoamento dos cimentos foi analisado de acordo com as normas ISO 6876/2012 e complementado pela avaliação em área. Placas de vidro foram confeccionadas nos diâmetros de 1×1×2 mm e 1×1×1 mm (comprimento, largura e altura), com uma cavidade central e quatro canaletas nas direções horizontal e vertical. Cada material foi colocado na cavidade central. Outra placa de vidro e um peso de metal foram colocados sobre o cimento e mantidos por 10 minutos. O conjunto placa de vidro/cimento foi escaneado usando micro-CT. O escoamento foi calculado por medição linear do material nas canaletas. O preenchimento (mm3) central foi calculado na cavidade central e o preenchimento lateral foi medido até 2 mm a partir da cavidade central. Os dados foram submetidos aos testes ANOVA/Tukey (α=0.05). Resultado Todos os cimentos avaliados apresentaram escoamento de acordo com as normas ISO 6876. Os materiais mostraram capacidade de preenchimento da cavidade central superior a 80% e preenchimento lateral superior a 75%. Não houve diferença no escoamento (mm e mm2) e na capacidade de preenchimento (mm3) proporcionada pelos materiais (p>0.05). Conclusão Todos os cimentos obturadores avaliados mostraram adequado escoamento e capacidade de preenchimento, sugerindo a aplicação clínica dos mesmos.
Descritores: Materiais Restauradores do Canal Radicular
Cimentos Dentários/análise
Microtomografia por Raio-X/métodos
-Tratamento do Canal Radicular
Tipo de Publ: Estudo Comparativo
Responsável: BR39.2 - Biblioteca Professora Maria Dilma de Oliveira Gonçalves


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Id: biblio-1095362
Autor: Machado, Juliane Freitas; Pires, Paula Maciel; Santos, Thais Maria Pires dos; Neves, Aline de Almeida; Lopes, Ricardo Tadeu; Visconti, Maria Augusta Portella Guedes.
Título: Root canal segmentation in cone-beam computed tomography: comparison with a micro-CT gold standard
Fonte: Braz. j. oral sci;18:e191627, jan.-dez. 2019. ilus.
Idioma: en.
Resumo: Aim: The purpose of this study was to compare root canal volumes (RCVs) obtained by means of cone beam computed tomography (CBCT) to those obtained by micro-computed tomography (micro-CT) after applying different segmentation algorithms. Methods: Eighteen extracted human teeth with sound root canals were individually scanned in CBCT and micro-CT using specific acquisition parameters. Two different images segmentation strategies were applied to both acquisition methods (a visual and an automatic threshold). From each segmented tooth, the root canal volume was obtained. A paired t-test was used to identify differences between mean values resulted from the experimental groups and the gold standard. In addition, Pearson correlation coefficients and the agreement among the experimental groups with the gold standard were also calculated. The significance level adopted was 5%. Results: No statistical differences between the segmentation methods (visual and automatic) were observed for micro-CT acquired images. However, significant differences for the two segmentation methods tested were seen when CBCT acquired images were compared with the micro-CT automatic segmentation methods used. In general, an overestimation of the values in the visual method were observed while an underestimation was observed with the automatic segmentation algorithm. Conclusion: Cone beam computed tomography images acquired with parameters used in the present study resulted in low agreement with root canal volumes obtained with a micro-CT tomography gold standard method of RCV calculation
Descritores: Tratamento do Canal Radicular
Imageamento Tridimensional
Tomografia Computadorizada de Feixe Cônico
Microtomografia por Raio-X
Responsável: BR218.1 - Biblioteca Carlos Henrique Robertson Liberalli


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Id: biblio-1056465
Autor: Cao, Zhenhua; Su, Baoke; Wang, Wei; Li, Zhijun; Wang, Haiyan; Wang, Xing; Zhang, Shaojie; Wang, Yidan; Guan, Huanhuan; Gao, Mingjie; Wang, Zhiqiang; Zhang, Yunfeng; Li, Xiaohe; Wang, Yan.
Título: A micro-CT study of different regions of the atlas / Un estudio de micro-CT de diferentes regiones del atlas
Fonte: Int. j. morphol;38(2):477-480, abr. 2020. tab, graf.
Idioma: en.
Projeto: National natural science foundation of China; . Inner Mongolia department of education youth science and technology; . Natural science foundation of the Inner Mongolia autonomous region.
Resumo: This study aimed to examine the differences in bone microarchitecture between different regions of the atlas in 28 dry atlas specimens using micro-CT, in order to explain the mechanism of the predilection sites of atlas fractures from the morphological point of view. A total of 28 dry specimens of intact adult atlas were randomly selected, scanned by micro-CT, and divided into a region from the anterior arch midpoint (AAM) to the lateral masses (LM), a LM region, and a region from the LM to the posterior arch midpoint (PAM). Trabecular thickness, separation, number, connectivity, and structure model index were measured for each of the three regions using the built-in software of the CT scanner. Trabecular thickness was all measured to be 0.11 ± 0.00 mm for AAM to LM, LM, and LM to PAM. Trabecular separation: AAM to LM > LM to PAM > LM. Trabecular number: LM > LM to PAM > AAM to LM. Connectivity: LM > LM to PAM > AAM to LM. Structure model index: LM > LM to PAM > AAM to LM. A lower trabecular number and connectivity and higher trabecular separation were seen in the anterior and posterior arches of the atlas, in which higher fracture rates were reported. By contrast, a higher trabecular number and connectivity and lower trabecular separation were seen in the lateral masses, in which lower fracture rates were reported.

Este estudio tuvo como objetivo examinar las diferencias en la microarquitectura ósea entre diferentes regiones del atlas en 28 muestras de atlas secas utilizando micro-CT, con el fin de informar el área de mayor frecuencia en las fracturas de atlas, desde el punto de vista morfológico. Se seleccionaron al azar un total de 28 muestras secas de atlas adultos intactas las que se escanearon por micro-CT y se dividieron en una región desde el punto medio del arco anterior (MAA) hasta las masas laterales (ML), una región ML y una región desde el ML hasta el punto medio del arco posterior (MAP). Se midió el grosor trabecular, la separación, el número, la conectividad y el índice del modelo de estructura para cada una de las tres regiones utilizando el software incorporado del escáner CT. El grosor trabecular se midió en 0,11 ± 0,00 mm para MAA a ML, ML y ML a MAP. Separación trabecular: MAA a ML> ML a MAP> ML. Número trabecular: ML> ML a MAP> MAA a ML. Conectividad: ML> ML a MAP> MAA a ML. Índice del modelo de estructura: ML> ML a MAP> MAA a ML. Se observó un menor número de estructuras trabeculares y conectividad y una mayor separación trabecular en los arcos anterior y posterior del atlas, en los que se informaron tasas de fracturas más altas. Por el contrario, se observó un mayor número de estructuras trabeculares y conectividad, y una menor separación trabecular en las masas laterales, en las que se observó un número menor de fracturas.
Descritores: Atlas Cervical/diagnóstico por imagem
Microtomografia por Raio-X/métodos
-Atlas Cervical/anatomia & histologia
Limites: Humanos
Responsável: CL1.1 - Biblioteca Central


  9 / 103 LILACS  
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Volpon, José Batista
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Id: biblio-989070
Autor: Guedes, Patrícia Madalena San Gregório; Zamarioli, Ariane; Botega, Iara Inácio; Silva, Raquel Assed Bezerra da; Issa, João Paulo Mardegan; Butezloff, Mariana Maloste; Sousa, Yara Terezinha Corrêa Silva; Ximenez, João Paulo Bianchi; Volpon, José Batista.
Título: Undernutrition impairs the quality of growth plate and trabecular and cortical bones in growing rats
Fonte: Acta cir. bras;34(3):e201900301, 2019. tab, graf.
Idioma: en.
Resumo: Abstract Purpose: To investigate the effects of dietary restriction on the growth plate and long bone tissue in growing rats. Methods: Sixty male Wistar rats were randomly assigned to two groups: Control (Con) and Diet-restricted (Res). After weaning, the Res rats were offered 50% of the chow ingested by the control (ad libitum food intake). The animals were subdivided into two subgroups with follow-ups up to 56 or 70 days. After euthanasia, the growth plate of tibias was analyzed by histomorphometry, micro-computed tomography, and mechanical test. The trabecular and compact bones were evaluated by histomorphometry, dual-energy X-ray absorptiometry, and micro-computed tomography (μCT). Real-time PCR was used to analyze gene expression. Results: Although dietary restriction did not alter gene expression, several phenotypic changes were seen in the growth plate; i.e., decrease in volume, reduction in total area and height, decrease in the area ossified zones, mechanical weakening, reduction in mass of trabecular and cortical bone, lower bone density, deterioration of the trabecular and cortical microarchitecture, and trabeculae with lower collagen deposition. Conclusion: Dietary restriction had severe detrimental effects on the growth plate and trabecular and cortical bone.
Descritores: Densidade Óssea/fisiologia
Desnutrição/complicações
Osso Esponjoso/crescimento & desenvolvimento
Osso Cortical/crescimento & desenvolvimento
Lâmina de Crescimento/crescimento & desenvolvimento
-Distribuição Aleatória
Ratos Wistar
Modelos Animais
Desnutrição/fisiopatologia
Microtomografia por Raio-X
Limites: Animais
Masculino
Ratos
Responsável: BR1.1 - BIREME


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Id: biblio-949374
Autor: Zhang, Zeming; Meng, Zibo; Wang, Yancun.
Título: Correlations of inhaled NO with the cTnI levels and the plasma clotting factor in rabbits with acute massive pulmonary embolism
Fonte: Acta cir. bras;33(8):664-672, Aug. 2018. tab, graf.
Idioma: en.
Resumo: Abstract Purpose: To investigate the correlation of inhaled nitric oxide (NO) on plasma levels of cardiac troponin I (cTnI) and von Willebrand factor (vWF), glycoprotein (GP) IIb/IIIa, granule membrane protein 140 (GMP-140) in rabbits with acute massive pulmonary embolism (PE). Methods: Thirty apanese white rabbits were divided into 3 groups, thrombus were injected in model group (n = 10), NO were inhalated for 24 h after massive PE in NO group (n = 10), saline were injected in control group (n = 10). The concentrations of vWF, GP IIb/IIIa, GMP-140 and cTnI were tested at 4, 8, 12, 16, 20, and 24 h, Correlation analyses were conducted between cTnI and vWF, GP IIb/IIIa, and GMP-140 by Pearson's correlation. Results: The concentration of cTnI and vWF, GP IIb/IIIa, and GMP-140 was increased in the model group, compared to control group. In the inhaled group, the concentrations of cTnI, vWF, GP IIb/IIIa, and GMP-140 were reduced compared to model group. There was a positive correlation between cTnI and vWF, GP IIb/IIIa, and GMP-140. Conclusion: Inhaled nitric oxide can lead to a decrease in levels of cardiac troponin I, von Willebrand factor, glycoprotein, and granule membrane protein 140, after an established myocardial damage, provoked by acute massive pulmonary embolism.
Descritores: Embolia Pulmonar/sangue
Fator de von Willebrand/análise
Complexo Glicoproteico GPIIb-IIIa de Plaquetas/análise
Complexo Glicoproteico GPIIb-IIIa de Plaquetas/efeitos dos fármacos
Selectina-P/sangue
Troponina I/sangue
Óxido Nítrico/administração & dosagem
-Embolia Pulmonar/patologia
Embolia Pulmonar/tratamento farmacológico
Valores de Referência
Fatores de Tempo
Administração por Inalação
Fator de von Willebrand/efeitos dos fármacos
Reprodutibilidade dos Testes
Resultado do Tratamento
Selectina-P/efeitos dos fármacos
Troponina I/efeitos dos fármacos
Modelos Animais de Doenças
Microtomografia por Raio-X
Ventrículos do Coração/patologia
Miocárdio/patologia
Limites: Animais
Coelhos
Responsável: BR1.1 - BIREME



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