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Id: lil-446759
Autor: García-Roco Pérez, Oscar N; Arredtondo López, Miguel; Castillo Betancourt, Esther María.
Título: Factores contribuyentes al diagnóstico tardío del carcinoma bucofaríngeo / Factors contributing to the late diagnosis of buccopharyngeal carcinoma
Fonte: Rev. cuba. estomatol;43(1), ene.-abr. 2006. tab.
Idioma: es.
Resumo: Se realizó un estudio observacional retrospectivo de una serie consecutiva de 249 pacientes con diagnóstico de carcinoma bucofaríngeo reportados al Registro Nacional del Cáncer (RNC) entre enero de 2000 y diciembre de 2004 en Camagüey, analizando retrospectivamente factores y hallazgos clínicos que puedan contribuir al diagnóstico tardío del carcinoma bucofaríngeo. Según sexo, edad, nivel de escolaridad, etapa y localización de la enfermedad, se estudió la duración y tipo de síntomas, así como la causa del diagnóstico tardío, separando las cohortes de pacientes muy jóvenes, muy ancianos y sin factores de riesgo. El 38,9 por ciento de los pacientes fue diagnosticado en estadio III y IV. La base de lengua, suelo de boca, gingiva y área retromolar fueron las localizaciones más frecuentes. El 54 por ciento de estos presentaron síntomas al menos 4 meses antes de ser diagnosticados y fue el dolor (32 por ciento) el más frecuente. La duración de los síntomas fue de 0 a 52 semanas (promedio de 8,6 semanas) para la etapa I, y de 0 a 260 semanas (promedio de 19,9 semanas) para la etapa IV. El 50,8 por ciento de las lesiones de la región anterior de suelo de boca se encontró en etapa III/IV en relación con el 75,7 por ciento de la región retromolar. El 75 por ciento de los pacientes con bajo nivel de escolaridad se presentó en etapa III/IV, en oposición al 54 por ciento de los pacientes con nivel elevado. El 71,3 por ciento de los pacientes sin hábitos tabaco/alcohol fueron diagnosticados tardíamente. El 20 por ciento de los pacientes consultaron al menos un profesional en relación con la enfermedad sin ser diagnosticados y remitidos adecuadamente. El 80 por ciento de los pacientes fue diagnosticado como parte del Programa Nacional de Control de Cáncer Bucal, aunque predominó el pesquisaje pasivo. Factores importantes en el diagnóstico tardío fueron el bajo nivel de escolaridad, localizaciones posteriores de la cavidad bucal por cuestiones de accesibilidad y la falta de factores de riesgo(AU)

An observational retrospective study of a consecutive series of 249 patients with diagnosis of buccopharyngeal carcinoma reported at the National Cancer Registry between January 2000 and December 2004, in Camagüey, was conducted. Factors and clinical findings that may contribute to the late diagnosis of the buccopharyngeal carcinoma were retrospectively analyzed. According to sex, age, educational level, and the stage and localization of the disease, the duration and type of the symptoms were studied, as well as the cause of the late diagnosis, by separating the very young from the very old cohorts and from those without risk factors. 38.9 percent of the patients were diagnosed in stage III and IV. The radix linguae, the floor of the mouth, gingiva and the retromolar area were the most frequent localizations. 54 percent of them presented symptoms at least 4 months before being diagnosed and pain (32 percent) was the most common of them. The symptoms lasted from 0 to 52 weeks (an average of 8.6 weeks) for stage I and from 0 to 260 weeks (an average of 19.9 weeks) for stage IV. 50.8 percent of the lesions of the anterior region of the floor of the mouth were in stage III/IV in relation to 75.7 percent of the retromolar region. 75 percent of the patients with low educational level were in stage III/IV compared to 54 percent of the patients with a high educational level. 71.3 percent of the patients without tobacco/alcohol habits were lately diagnosed. 20 percent of the patients visited at least a professional in connection with the disease without being adequately diagnosed and referred. 80 percent of the patients were diagnosed as part of the National Program of Oral Cancer Control, though there was a predominance of the passive screening. The low educational level, the posterior localizations of the oral cavity due to accesability questions and the lack of risk factors were important factors in the late diagnosis(AU)
Descritores: Planos e Programas de Saúde
Neoplasias Bucais/diagnóstico
Fatores de Risco
Detecção Precoce de Câncer/métodos
-Estudos Retrospectivos
Estudos Observacionais como Assunto
Limites: Humanos
Responsável: CU1.1 - Biblioteca Médica Nacional


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Id: biblio-839692
Autor: Curotto, Mariana; Barletta, Paula; Paolino, Melisa; Arrossi, Silvina.
Título: La perspectiva de los agentes sanitarios sobre la incorporación programática de la autotoma del test de VPH / Health agents’ perspective on the incorporation of self-collected samples in HPV screening programs / A perspectiva dos agentes sanitários sobre a incorporação programada da autoadministração do teste de HPV
Fonte: Cad. saúde pública (Online);33(4):e00138515, 2017. tab.
Idioma: es.
Resumo: Resumen: El objetivo de este estudio fue analizar la percepción que poseen los agentes sanitarios sobre el ofrecimiento de la autotoma del test de VPH a las mujeres y el grado de acuerdo de los agentes para incorporarla a sus tareas diarias. Para ello, se aplicó una encuesta auto-administrada a 127/191 agentes sanitarios que participaron del Proyecto EMA (Proyecto Evaluación Modalidad Autotoma), llevado a cabo en la provincia de Jujuy (Argentina) entre 2012-2013. Los agentes sanitarios que tuvieron y no la experiencia de ofrecer la autotoma manifestaron un alto grado de acuerdo para la adopción de la estrategia (78,7%), dado su potencial para prevenir el cáncer cervicouterino y los aportes que brinda al cuidado de la salud de las mujeres bajo su cobertura. Sin embargo, señalaron la sobrecarga de trabajo y los problemas de articulación con el sistema formal de salud, como los principales obstáculos para ofrecer esta modalidad en el futuro. Este estudio encontró que la autotoma es una práctica que puede ser adoptada por los agentes sanitarios de la provincia de Jujuy, pero debe ir acompañada de acciones de apoyo por parte del sistema de salud formal.

Abstract: The objective of this study was to analyze health agents’ perception of self-collecting of samples for HPV testing among women and the degree of agreement by the agents to incorporate this approach into their daily tasks. A self-administered questionnaire was applied to 127/191 health agents that participated in the EMA Project (Proyecto Evaluación Modalidad Autotoma) in the province of Jujuy, Argentina, in 2012-2013. The health agents with and without the experience of offering self-collected sampling expressed a high degree of agreement towards adoption of the strategy (78.7%), given its potential to prevent cervical cancer and its contribution to health care for the women under their coverage. However, the health agents identified the extra work and problems linking to the formal health system as the main barriers to offering this modality in the future. The study found that self-collecting of samples is a practice that can be adopted by health agents in the province of Jujuy, but that it should be accompanied by support measures from the formal health system.

Resumo: Este estudo objetivou analisar a percepção que possuem os agentes sanitários sobre o oferecimento da autoadministração do teste de HPV a mulheres e o nível de compromisso dos agentes em incorporá-la a suas tarefas diárias. Para isso, foi aplicada uma pesquisa autoadministrada entre 127/191 agentes sanitários que participaram do Projeto EMA (Proyecto Evaluación Modalidad Autotoma), realizada na província de Jujuy (Argentina) no período 2012-2013. Os agentes sanitários que tiveram e não a experiência de oferecer a autoadministração manifestaram um alto grau de compromisso para a aprovação da estratégia (78,7%), devido ao seu potencial para prevenir o câncer do colo do útero e os aportes que presenta para o cuidado da saúde das mulheres sob sua cobertura. No entanto, mostraram uma sobrecarga de trabalho e problemas de articulação com o sistema público de saúde, como os principais obstáculos para oferecer esta modalidade em um futuro. Este estudo encontrou que a autoadministração é una prática que pode ser adotada pelos agentes sanitários da província de Jujuy, no entanto deve ir acompanhada de ações de apoio por parte do sistema público de saúde.
Descritores: Autocuidado
Manejo de Espécimes/psicologia
Neoplasias do Colo do Útero/prevenção & controle
Programas de Rastreamento/métodos
Agentes Comunitários de Saúde
Infecções por Papillomavirus/diagnóstico
-Papillomaviridae
Argentina
Manejo de Espécimes/métodos
Cooperação do Paciente
Detecção Precoce de Câncer
Limites: Humanos
Masculino
Feminino
Adulto
Responsável: BR1.1 - BIREME


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Id: biblio-1119245
Autor: Hegde, Nidarsh D; Hegde, Mithra N.
Título: Screening for oral cancers: future perspectives
Fonte: J. oral res. (Impresa);7(1):11-13, ene. 22, 2018.
Idioma: en.
Descritores: Neoplasias Bucais/diagnóstico
Neoplasias Bucais/etiologia
Neoplasias Bucais/psicologia
-Neoplasias Bucais/patologia
Programas de Rastreamento
Detecção Precoce de Câncer
Limites: Humanos
Responsável: CL30.1 - Biblioteca


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Id: biblio-904098
Autor: Bueno, André Tito Pereira; Capelasso, Vladimir Lisboa; Pacheco, Rafael Leite; Latorraca, Carolina de Oliveira Cruz; Castria, Tiago Biachi de; Pachito, Daniela Vianna; Riera, Rachel.
Título: What do Cochrane systematic reviews say about the clinical effectiveness of screening and diagnostic tests for cancer? / O que as revisões sistemáticas de Cochrane falam sobre a eficácia clínica dos testes de rastreamento e diagnóstico para o câncer?
Fonte: Säo Paulo med. j;135(4):401-410, July-Aug. 2017. tab.
Idioma: en.
Resumo: ABSTRACT CONTEXT AND OBJECTIVE: The purpose of screening tests for cancer is to detect it at an early stage in order to increase the chances of treatment. However, their unrestrained use may lead to unnecessary examinations, overdiagnosis and higher costs. It is thus necessary to evaluate their clinical effects in terms of benefits and harm. DESIGN AND SETTING: Review of Cochrane systematic reviews, carried out in the Discipline of Evidence-Based Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo. METHODS: Cochrane reviews on the clinical effectiveness of cancer screening procedures were included. Study titles and abstracts were independently assessed by two authors. Conflicts were resolved by another two authors. Findings were summarized and discussed. RESULTS: Seventeen reviews were selected: fifteen on screening for specific cancers (bladder, breast, colorectal, hepatic, lung, nasopharyngeal, esophageal, oral, prostate, testicular and uterine) and two others on cancer in general. The quality of evidence of the findings varied among the reviews. Only two reviews resulted in high-quality evidence: screening using low-dose computed tomography scans for high-risk individuals seems to reduce lung cancer mortality; and screening using flexible sigmoidoscopy and fecal occult blood tests seems to reduce colorectal cancer mortality. CONCLUSION: The evidence found through Cochrane reviews did not support most of the commonly used screening tests for cancer. It is recommended that patients should be informed of the possibilities of false positives and false negatives before they undergo the tests. Further studies to fully assess the effectiveness of cancer screening tests and adverse outcomes are required.

RESUMO CONTEXTO E OBJETIVO: O objetivo do teste de rastreamento para o câncer é detectá-lo em um estágio inicial, a fim de aumentar as chances de cura. Contudo, seu uso descomedido pode levar a exames desnecessários, sobrediagnóstico e aumento de custos. Portanto, é necessário que se avalie a repercussão clínica do rastreamento em termos de benefícios e riscos. TIPO DE ESTUDO E LOCAL: Revisão de revisões sistemáticas Cochrane realizada na Disciplina de Medicina Baseada em Evidências da Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP). MÉTODOS: Foram incluídas revisões sobre efetividade clínica de testes de rastreamento para câncer. Os títulos e resumos foram avaliados independentemente por dois autores e divergências foram resolvidas por outros dois. Os achados foram resumidos e discutidos. RESULTADOS: 17 revisões sistemáticas foram incluídas: 15 sobre rastreamento para cânceres específicos (vesical, mamário, colorretal, hepático, pulmonar, nasofaríngeo, esofágico, oral, prostático, testicular, uterino) e duas para câncer em geral. A qualidade das evidências encontradas pelas revisões variou muito. Duas revisões encontraram evidências de alta qualidade: o rastreamento com tomografia em dose baixa em pacientes de alto risco parece reduzir a mortalidade por câncer pulmonar; e rastreamento com sigmoidoscopia flexível e pesquisa de sangue oculto nas fezes parece reduzir a mortalidade por câncer colorretal. CONCLUSÃO: As evidências de revisões sistemáticas Cochrane não indicam a realização dos testes mais usados para rastreamento de câncer. Recomenda-se que os pacientes sejam informados sobre as possibilidades de falsos positivos e de falsos negativos antes de serem submetidos aos testes. Estudos adicionais para avaliar melhor a eficácia de testes de rastreamento para o câncer e os eventos adversos são necessários.
Descritores: Medicina Baseada em Evidências
Detecção Precoce de Câncer/normas
-Literatura de Revisão como Assunto
Limites: Humanos
Responsável: BR1.1 - BIREME


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Id: biblio-1281314
Autor: Piemonte, Eduardo David; Gilligan, Gerardo M; Lazos, Jerónimo P; Panico, René L.
Título: Tinción con azul de toluidina en biopsia dirigida de lesiones displásicas de la mucosa bucal: informe de casos clínicos / Toluidine blue guided biopsy of dysplastic lesions of the oral mucosa: clinical cases report
Fonte: Rev. Asoc. Odontol. Argent;109(1):49-58, ene.-abr. 2021. ilus.
Idioma: es.
Resumo: Objetivo: Los desórdenes de mucosa bucal potencialmente malignos pueden presentar áreas displásicas. En estos casos, la biopsia es un procedimiento imprescindible para un correcto diagnóstico. La inspección visual y la palpación, como método de selección del área de biopsia, ofrecen sensibilidad y especificidad adecuadas pero mejorables. El objetivo de este artículo es presentar una serie de casos clínicos en los que se describen el empleo y la interpretación de la tinción vital con azul de toluidina como método complementario para contribuir a una mejor elección del área de biopsia. Casos clínicos: Se trata de siete casos de lesiones con sospecha de displasia epitelial en mucosa bucal. En cada uno se detalla la correlación de las áreas teñidas con las manifestaciones clínicas y con el diagnóstico de displasia. Además, se muestran patrones de tinción considerados falsos positivos. En la interpretación de la tinción positiva, se tuvieron en cuenta el aspecto superficial y el color de la lesión teñida. El empleo combinado de inspección, palpación y tinción vital podría constituir un procedimiento integral de utilidad para obtener mayor precisión en la determinación del sitio de biopsia en comparación con los mismos procedimientos aplicados de manera individual. En la interpretación de la tinción positiva con azul de toluidina deberían considerarse el aspecto superficial y el color de la lesión teñida (AU)

Aim: Potentially Malignant Disorders in the oral cavity can present dysplastic areas. In these cases, the biopsy is an essential procedure for a correct diagnosis. Visual inspection and palpation, are adequate methods to select the area for the biopsy, however there is margin for improvement. The objective of this article is to present a series of clinical cases in which the use and interpretation of vital staining with Toluidine Blue is described as a complementary method to contribute to a better choice of the biopsy area. Clinical cases: Seven clinical cases that presented lesions with suspected epithelial dysplasia in the oral mucosa were presented. The correlation of the stained areas with the clinical manifestations and with the diagnosis of dysplasia is detailed in each case. Staining patterns considered false positives are also shown. In the interpretation of the positive staining, the superficial appearance and color of the stained lesion were considered. The combined use of inspection, palpation and vital staining could constitute a useful comprehensive procedure to obtain greater precision in determining the biopsy site in relation to the same procedures applied individually. In the interpretation of the positive staining with Toluidine Blue, the superficial appearance and color of the stained lesion should be considered (AU)
Descritores: Lesões Pré-Cancerosas/classificação
Cloreto de Tolônio
Detecção Precoce de Câncer/métodos
Mucosa Bucal/lesões
-Palpação
Biópsia/métodos
Neoplasias Labiais/diagnóstico
Diagnóstico Clínico
Sensibilidade e Especificidade
Carcinoma de Células Escamosas de Cabeça e Pescoço/diagnóstico
Limites: Humanos
Masculino
Feminino
Adulto
Pessoa de Meia-Idade
Idoso
Tipo de Publ: Relatos de Casos
Responsável: AR29.1 - Biblioteca


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Id: biblio-1014628
Autor: Yörük, Selda; Açikgöz, Ayla; Türkmen, Hülya; Ergör, Gül.
Título: Risk factors and relationship between screening periodicity and risk of cervical cancer among nurses and midwives. A cross-sectional study
Fonte: Säo Paulo med. j;137(2):119-125, Mar.-Apr. 2019. tab.
Idioma: en.
Resumo: ABSTRACT BACKGROUND: If nurses and midwives undergo cervical cancer screening regularly, they can become role models for other women regarding this screening. OBJECTIVES: The aims here were (i) to determine factors associated with undergoing cervical cancer screening; and (ii) to examine the association of cervical cancer screening periodicity with cervical cancer risk levels among nurses and midwives. DESIGN AND SETTING: Cross-sectional study in a public hospital. METHODS: 466 nurses and midwives participated in this study. The relationships between undergoing Pap smear screening and sociodemographic characteristics, cervical cancer risk factors, perception of cervical cancer risk and calculated cervical cancer risk levels were examined. Cervical cancer risk levels were determined using the "Your Disease Risk" assessment tool (Washington University). RESULTS: 35% of the nurses and midwives had undergone Pap smear testing at least once in their lifetimes. The odds of having undergone Pap smear testing were higher among smokers (odds ratio, OR: 2.08; 95% confidence interval, CI: 1.24-3.48) and among those who perceived their risk of cervical cancer to be high (OR: 3.60; 95% CI: 1.36-9.51). The frequency of undergoing Pap smear testing at least once in a lifetime was higher among primiparae (OR: 17.99; 95% CI: 6.36-50.84) and secundiparae (OR: 41.53; 95% CI: 15.01-114.91) than among nulliparae. No relationship was found between Pap smear test periodicity and calculated risk level. CONCLUSION: There is a need to assess motivational barriers that might lead to low levels of Pap smear screening among nurses and midwives who are role models for women regarding cervical cancer prevention.
Descritores: Neoplasias do Colo do Útero/diagnóstico
Detecção Precoce de Câncer
Tocologia/estatística & dados numéricos
Enfermeiras e Enfermeiros/estatística & dados numéricos
-Fatores Socioeconômicos
Fatores de Tempo
Programas de Rastreamento
Estudos Transversais
Fatores de Risco
Teste de Papanicolaou
Limites: Humanos
Feminino
Adulto
Adulto Jovem
Responsável: BR1.1 - BIREME


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Id: biblio-1144328
Autor: Viaña González, Luis Fernando.
Título: Retos para el control del cáncer en Colombia: ante todo más acción / Challenges for breast cancer control in Colombia: first of all, more action
Fonte: Rev. colomb. cancerol;24(3):101-102, jul.-set. 2020.
Idioma: es.
Descritores: Neoplasias da Mama/prevenção & controle
-Neoplasias da Mama/diagnóstico
Colômbia
Detecção Precoce de Câncer
Limites: Humanos
Feminino
Tipo de Publ: Editorial
Responsável: CO40.1 - Biblioteca Médica


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Id: biblio-961371
Autor: Navarro, María E; Razmilic, Dravna; Araos, Isabel; Rodrigo, Andrés; Andia, Marcelo E.
Título: Rendimiento de la mamografía espectral de energía dual con contraste en la detección de cáncer de mama: experiencia en un centro de referencia / Contrast-enhanced spectral mammography: experience in 465 examinations
Fonte: Rev. méd. Chile;146(2):141-149, feb. 2018. tab, graf.
Idioma: es.
Resumo: Background: Contrast-enhanced spectral mammography or "contrast mammography" has a better cost effectiveness than breast magnetic resonance for confirmation of suspicious lesions detected on breast screening programs. Aim: To report the experience of a single center in Santiago. Material and Methods: All patients referred for contrast mammography between July 2015 and October 2017 were studied. We recorded the patient risk factors for breast cancer. In 85 patients with suspicious lesions, biopsy results were available. Results: We analyzed 465 contrast mammographies. The most common clinical indications were suspicion of cancer and previous inconclusive studies. Mass type lesions were detected in 33% of the studies. Non-mass-type lesions were observed in 10% of cases and findings compatible with papillomatosis in 2%. Fifty five percent of the studies had no visible lesions. In the 85 patients with a pathological study of the biopsy, the sensitivity of the contrast mammography was 100%, with a diagnostic accuracy of 85%, positive and negative predictive values of 82 and 100% respectively. Conclusions: Contrast mammography can be of great use for the assessment of patients with an altered conventional mammography, before indicating a magnetic resonance imaging or a percutaneous biopsy.
Descritores: Neoplasias da Mama/diagnóstico por imagem
Mamografia/métodos
Aumento da Imagem
Meios de Contraste
-Mamografia/estatística & dados numéricos
Reprodutibilidade dos Testes
Fatores de Risco
Sensibilidade e Especificidade
Análise Custo-Benefício
Detecção Precoce de Câncer
Limites: Humanos
Feminino
Adulto
Pessoa de Meia-Idade
Idoso
Idoso de 80 Anos ou mais
Adulto Jovem
Responsável: CL1.1 - Biblioteca Central


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Id: biblio-1043438
Autor: Department of Obstetrics and GynecologyTeixeira, Júlio César; Maestri, Carlos Afonso; , Department of StatisticsMachado, Helymar da Costa; Department of Obstetrics and GynecologyZeferino, Luiz Carlos; Department of Obstetrics and GynecologyCarvalho, Newton Sérgio de.
Título: Incidence rates and temporal trends of cervical cancer relating to opportunistic screening in two developed metropolitan regions of Brazil: a population-based cohort study
Fonte: Säo Paulo med. j;137(4):322-328, July-Aug. 2019. tab, graf.
Idioma: en.
Projeto: GlaxoSmithKline Biologicals S.A..
Resumo: ABSTRACT BACKGROUND: Brazilian opportunistic screening programs for cervical cancer have limited impact. In the regions of two cities (Campinas and Curitiba) with high human development indices, consistent information from 96-97% of all cervical cancer cases managed within the public healthcare system is available. OBJECTIVE: To estimate the incidence rate (IR) and temporal trends in these regions, covering 2001-2012. DESIGN AND SETTING: A population-based cohort study was conducted under the assumption that all cervical cancer cases were managed in cancer referral center hospitals. METHODS: 3,364 records (1,646 from Campinas; 1,718 from Curitiba) were analyzed to provide estimates of IR, age-standardized IR (ASR) and cervical cancer trends (shown per 100,000 women/year). Longitudinal patterns were analyzed using linear regression and shown as annual percentage change (APC); P < 0.05 for significance. RESULTS: Annual IR and ASR estimates for cervical cancer ranged from 3.8 to 8.0 over 2001-2012, decreasing over more recent years, and were similar for the two regions. The age-specific IR was about 50% lower among women aged 45 years or older (IR-2001/IR-2012: Campinas = 14.8/8.0; Curitiba = 18.7/8.3; P < 0.001). There was an increasing APC trend in Campinas among women aged 15-24 years, and a decreasing IR trend for squamous-cell histology in both regions (P < 0.05). CONCLUSION: Cervical cancer incidence estimates showed slowly decreasing trends in both regions, most evidently for women aged 45 years or older and for squamous-cell histology. These findings reflect the opportunistic nature of the population screening program, despite the comparatively high economic development level in the two regions.
Descritores: Neoplasias do Colo do Útero/epidemiologia
Detecção Precoce de Câncer/estatística & dados numéricos
-População Urbana
Brasil/epidemiologia
Neoplasias do Colo do Útero/diagnóstico
Programas de Rastreamento
Incidência
Estudos de Coortes
Análise Espaço-Temporal
Limites: Humanos
Feminino
Adolescente
Adulto
Pessoa de Meia-Idade
Idoso
Adulto Jovem
Responsável: BR1.1 - BIREME


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Id: biblio-1099384
Autor: Jordão, Paula Moskovics; Women's Health SectorRussomano, Fábio Bastos; Gerbauld, Gabriella Tostes; Andrade, Cecília Vianna de; Osorio, Clarice Fraga Esteves Maciel.
Título: Accuracy of endocervical cytological tests in diagnosing preinvasive lesions of the cervical canal in patients with type 3 transformation zone: a retrospective observational study
Fonte: Säo Paulo med. j;138(1):47-53, Jan.-Feb. 2020. tab, graf.
Idioma: en.
Resumo: ABSTRACT BACKGROUND: Cervical cancer screening in Brazil is done using Pap smears. Women who are most likely to have a preinvasive lesion or cervical cancer are immediately referred for colposcopy. OBJECTIVE: The aim of this study was to evaluate the diagnostic performance of endocervical cytological tests in diagnosing preinvasive cervical lesions in women with initial high-grade squamous intraepithelial lesions (HSIL), or atypical squamous cells in which high-grade lesions could not be ruled out (ASC-H), or atypical glandular cells (AGC), and whose colposcopy did not show any abnormalities, with no fully visible transformation zone (types 2 and 3). DESIGN AND SETTING: Retrospective observational study conducted in Rio de Janeiro, Brazil. METHODS: Data from women who came to the cervical pathology outpatient clinic between January 2012 and April 2017 were analyzed. The results from endocervical cytological tests were compared with the final diagnosis, which was obtained through examination of a surgical specimen or, among women who did not undergo an excisional procedure, after cytological and colposcopic follow-up for two years. RESULTS: We included 78 women. The sensitivity of endocervical cytological tests was 72.7%; specificity 98.5%; positive and negative predictive values 88.9% and 95.6%, respectively; and positive and negative likelihood ratios 48.7 and 0.28. CONCLUSION: Endocervical cytological tests are simple, inexpensive and noninvasive, and form a reliable method for determining management among patients with HSIL, ASC-H and AGC cytological findings and negative colposcopic findings without visualization of the squamocolumnar junction.
Descritores: Neoplasias do Colo do Útero
Neoplasia Intraepitelial Cervical
-Esfregaço Vaginal
Brasil
Estudos Retrospectivos
Colposcopia
Detecção Precoce de Câncer
Limites: Humanos
Feminino
Gravidez
Tipo de Publ: Estudo Observacional
Responsável: BR1.1 - BIREME



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