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Atallah, Alvaro Nagib
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Id: biblio-962722
Autor: Riera, Rachel; Braga, Vinícius Lopes; Rocha, Luana Pompeu dos Santos; Bernardo, Daniel Damasceno; Andrade, Luísa Avelar Fernandes de; Hsu, Jessica Chiu; Silva, Luciana Di Giovanni Marques da; Suetsugu, Rodrigo Cesar de Sá; Dittrich, Nicole Hosni; Lima, Lucas Riguete Pereira de; Silveira, Vicente Penido da; Kruglensky, Barbara Caon; Leonel, Letícia de Freitas; Barros, Edivando de Moura; Costa, Anderson Adriano Leal Freitas da; Quintella, Miguel Lins; Pacheco, Rafael Leite; Cruz, Carolina de Oliveira; Martimbianco, Ana Luiza Cabrera; Pachito, Daniela Vianna; Mozetic, Vania; Teixeira, Tatiana de Bruyn Ferraz; Torloni, Maria Regina; Atallah, Alvaro Nagib.
Título: What do Cochrane systematic reviews say about new practices on integrative medicine?
Fonte: Säo Paulo med. j;136(3):251-261, May-June 2018. tab.
Idioma: en.
Resumo: ABSTRACT BACKGROUND: This study identified and summarized all Cochrane systematic reviews (SRs) on the effects of ten integrative practices that were recently added to the Brazilian public healthcare system (SUS). DESIGN AND SETTING: Review of systematic reviews, conducted in the Discipline of Evidence-Based Medicine, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (Unifesp). METHODS: Review of Cochrane SRs on the following interventions were identified, summarized and critically assessed: apitherapy, aromatherapy, bioenergetics, family constellation, flower therapy, chromotherapy, geotherapy, hypnotherapy, hand imposition or ozone therapy. RESULTS: We included a total of 16 SRs: 4 on apitherapy, 4 on aromatherapy, 6 on hypnotherapy and 2 on ozone therapy. No Cochrane SR was found regarding bioenergetics, family constellation, chromotherapy, clay therapy, flower therapy or hand imposition. The only high-quality evidence was in relation to the potential benefit of apitherapy, specifically regarding some benefits from honey dressings for partial healing of burn wounds, for reduction of coughing among children with acute coughs and for preventing allergic reactions to insect stings. CONCLUSION: Except for some specific uses of apitherapy (honey for burn wounds and for acute coughs and bee venom for allergic reactions to insect stings), the use of ten integrative practices that have recently been incorporated into SUS does not seem to be supported by evidence from Cochrane SRs.
Descritores: Literatura de Revisão como Assunto
Medicina Integrativa/métodos
-Ozônio/uso terapêutico
Aromaterapia/métodos
Medicina Baseada em Evidências/normas
Apiterapia/métodos
Hipnose/métodos
Limites: Humanos
Tipo de Publ: Revisão
Responsável: BR1.1 - BIREME


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Id: biblio-1179410
Autor: Beltrán Delgado, Mailin; Perdomo Delgado, Johann; González Pla, Evelyn Anie; Pérez Romero, Marilda; Rosales Pérez, Maribel; Delgado Iznaga, Emilio.
Título: Producción y consumo de fitofármacos y apifármacos durante la pandemia de COVID-19 en Cuba, marzo a junio de 2020 / Production and consumption of phytopharmaceuticals and apipharmaceuticals during the COVID-19 pandemic in Cuba, March to June 2020
Fonte: Rev. peru. med. integr;5(3):95-99, 2020. tab, graf.
Idioma: es.
Resumo: Objetivos. Determinar el aporte del personal de los servicios farmacéuticos comunitarios al aseguramiento de la producción de fitofármacos y apifármacos elaborados a nivel localdispensarial, incluidos en el protocolo de actuación nacional para la COVID-19, así como el consumo de estas formulaciones. Materiales y métodos. Se realizó un estudio retrospectivo, observacional, descriptivo y longitudinal, donde se analizaron los informes mensuales de producción, en el período comprendido entre marzo y junio. De estos se obtuvo la información de los diez fitofármacos y apifármacos seleccionados. Se determinaron los planes de producción para cada una de estas formulaciones y su cumplimiento, así como el consumo de estos. Resultados. Entre marzo y junio se produjeron en el país 7 401 001 unidades de los diez fitofármacos y apifármacos seleccionados, el 125,5% de lo planificado. De ellos, la mayor producción correspondió al orégano jarabe 10% (1 725 156 unidades) y al Imefasma jarabe (1 648 037 unidades). El aloe jarabe (50%) y la cebolla jarabe (10%) fueron los dos fitofármacos con mayor porcentaje de producción con respecto al plan. La Habana fue la provincia con el mayor volumen de producción (1 315 008 unidades); la menor producción correspondió al municipio especial Isla de la Juventud (18 107 unidades). De las 7 401 001 unidades producidas en el período, se consumieron 6 754 910 (91,3%). Conclusiones. Desde los servicios farmacéuticos se aseguró la producción, a nivel local-dispensarial, de los diez fitofármacos y apifármacos seleccionados para el enfrentamiento de la pandemia de COVID-19 en Cuba. Se sobrepasó la producción de todos estos fitofármacos y apifármacos y su consumo fue alto.

Objectives. To determine the contribution of the staff of the community pharmaceutical services to ensuring the production of phytopharmaceuticals and apipharmaceuticals produced at the local-dispensary level, included in the national action protocol for COVID-19, as well as the consumption of these formulations. Materials and methods. It was carried out a retrospective, observational, descriptive, and longitudinal study, where the monthly reports of production were analyzed, in the period from March to June. From these, the information of the ten selected phytopharmaceuticals and apipharmaceuticals was obtained. The production plans for each of these formulations and their compliance were determined, as well as their consumption. Results. Between March and June, 7,401,001 units of the ten selected phytopharmaceuticals and apipharmaceuticals were produced in the country, 125.5% of what was planned. Of these, the highest production corresponded to oregano syrup 10% (1,725,156 units) and Imefasma syrup (1,648,037 units). Aloe syrup (50%) and onion syrup (10%) were the two phytopharmaceuticals with the highest percentage of production with respect to the plan. Havana was the province with the highest production volume (1 315 008 units); the lowest production corresponded to the special municipality Isle of Youth (18 107 units). Of the 7,401,001 units produced in the period, 6,754,910 (91.3%) were consumed. Conclusions. From the pharmaceutical services, it was ensured the production, at a local-dispensary level, of the ten phytopharmaceuticals and apipharmaceuticals selected for the confrontation of the COVID-19 pandemic in Cuba. The production of all these phytopharmaceuticals and apipharmaceuticals was surpassed and their consumption was high.
Descritores: Infecções por Coronavirus/epidemiologia
Apiterapia
Fitoterapia
-Cuba
Dispensários de Medicamentos
Medicina Tradicional
Responsável: BR1.1 - BIREME


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Id: biblio-1140505
Autor: Betancourt Pulsán, Anselma; García Collado, Maricel; Fernández Ortega, Maritza; Torres Quiala, Marlene; Sánchez García, Alejandro Javier.
Título: Fitoterapia y apiterapia en la obra de José Martí / Phytotherapy and apitherapy in the work of José Martí
Fonte: Rev. inf. cient;92(4):945-955, 2015.
Idioma: es.
Resumo: El origen dela Medicina Naturaly Tradicional está íntimamente unido al de la humanidad y al hombre en su lucha por la supervivencia.La Medicina Naturaly Tradicional reafirma la integralidad del enfoque médico, incorpora enfoques preventivos de las enfermedades y ofrece herramientas terapéuticas y de rehabilitación para muchos problemas de salud, tanto agudos como crónicos. Se realizó una revisión completa del Diario de Campaña de José Martí y se seleccionaron los pasajes donde hace referencia a plantas, frutas y miel. Las estrategias histórico-social y la de Medicina Bioenergética y Natural aunadas en la docencia de pre y postgrado en las Ciencias Médicas desde la lectura de pasajes de su Diario de Campaña contribuye a divulgar y estimular la lectura y a incrementar el nivel de conocimientos, de la obra escrita por José Martí, al mismo tiempo la evidencia de la utilización de la fitoterapia y la apiterapia.
Descritores: Apiterapia
Fitoterapia
-Terapias Complementares
Cuba
Medicina Tradicional
Limites: História do Século XIX
Tipo de Publ: Artigo Histórico
Responsável: BR1.1 - BIREME


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Id: biblio-1056928
Autor: Santos, Heidy C. dos; Vieira, Dielson S; Yamamoto, Sandra M; Costa, Mateus M; Sá, Maria C. A; Silva, Eva M. S; Silva, Tania M. S.
Título: Antimicrobial activity of propolis extract fractions against Staphylococcus spp. isolated from goat mastitis / Atividade antimicrobiana de frações do extrato de própolis frente à Staphylococcus spp. isolados de mastite caprina
Fonte: Pesqui. vet. bras = Braz. j. vet. res;39(12):954-960, Dec. 2019. tab, graf, ilus.
Idioma: en.
Resumo: The indiscriminate use of antibiotics in the treatment of caprine mastitis causes the appearance of resistant microorganisms, besides leaving residues in milk, putting at risk to human health. In this way, propolis is an alternative in the treatment of diseases because it has antimicrobial activity, mainly because of the presence of flavonoids in its composition. The aim of this study was to evaluate the antimicrobial potential of propolis to Staphylococcus spp. Isolated from cases of goat mastitis and qualify the crude ethanoic extract by high performance liquid chromatography (HPLC). In this study, the minimum bactericidal concentration values of propolis extracts in ethanol, ethyl acetate and hexane showed that the best concentrations capable of promoting the highest mortality of the isolates of Staphylococcus spp. from mastitis in goats, were 6250, 3125 and 1562.5µg/mL, respectively. By the microplate adherence test, it was found that 20.78% isolates were not able to form biofilm, 14.70% were classified as moderate and 64.70% were weak and none as a strong biofilm producer. Propolis in its different diluents was able to affect the formation of biofilm and showed a pronounced marked antimicrobial activity against Staphylococcus spp. strains and may be indicated for use in in vivo studies.(AU)

O uso indiscriminado de antibióticos no tratamento de mastite caprina leva ao desenvolvimento de micro-organismos resistentes que poderão estar presentes em alimentos, colocando em risco a saúde humana. Dessa forma, a própolis surge como uma alternativa para o tratamento de doenças por possuir uma ação antimicrobiana, principalmente pela presença de flavonoides em sua composição. O objetivo desse estudo foi avaliar o potencial antimicrobiano da própolis frente à Staphylococcus spp. isolados de casos de mastite caprina e qualificar o extrato etanoico bruto por cromatografia líquida de alta eficiência (CLAE-DAD). Neste estudo, os valores de concentração bactericida mínima (CBM) dos extratos de própolis em álcool etílico, acetato de etila e hexano nos isolados foram de 6250, 3125 e 1562,5µg/mL, respectivamente. Pelo teste de aderência à microplacas, observou-se que 20,78% dos microorganismos, não foram capazes de formar biofilme, 14,70% foram classificados como moderados, 64,70% em fracos e nenhum como forte produtor de biofilme. A própolis em seus diferentes diluentes foi capaz de afetar a formação de biofilme e apresentou significativa atividade antimicrobiana frente a cepas de Staphylococcus spp., podendo ser indicada para utilização em estudos "in vivo".(AU)
Descritores: Própole/uso terapêutico
Infecções Estafilocócicas/terapia
Infecções Estafilocócicas/veterinária
Staphylococcus/isolamento & purificação
Cabras/microbiologia
Apiterapia/veterinária
Mastite/terapia
Mastite/veterinária
Limites: Animais
Feminino
Responsável: BR68.1 - Biblioteca Virginie Buff D'Ápice


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Id: lil-783794
Autor: Medeiros, Vanessa de Fátima Lima Paiva; Azevedo, Ítalo Medeiros; Rêgo, Amália Cínthia Meneses; Egito, Eryvaldo Sócrates Tabosa do; Araújo-Filho, Irami; Medeiros, Aldo Cunha.
Título: Antibacterial properties and healing effects of Melipona scutellaris honey in MRSA-infected wounds of rats
Fonte: Acta cir. bras;31(5):327-332, May 2016. tab.
Idioma: en.
Resumo: ABSTRACT PURPOSE : To investigate the antimicrobial, immunological and healing effects of Melipona scutellaris honey on infected wounds of rat skin. METHODS: Twenty four Wistar rats were distributed in four groups (6-each). The uninfected skin wounds of group I rats were treated daily with saline for 7 days. Uninfected wounds (group II) rats were treated with honey. In group III (treated with saline) and group IV (treated with honey) wounds were inoculated with MRSA ATTC43300. The first bacterial culture was performed 24 hours later. In the 7th day new culture was done, and wound biopsies were used for cytokines dosage and histopathology. RESULTS: In group I and III rats the CFU/g count of S. aureus in wounds was zero. In group II rats the CFU/g counts in the wound tissue were significantly higher than in wounds of group IV rats. The density histopathological parameters and the expression of TNF-α, IL1-β, Il-6 were significantly higher on wounds of group IV then in the other groups. CONCLUSION: Honey of Melipona scutellaris was effective in the management of infected wounds, by significant bacterial growth inhibition, enhancement of cytokine expression, and positively influenced the wound repair.
Descritores: Infecções Estafilocócicas/terapia
Cicatrização
Staphylococcus aureus Resistente à Meticilina
Apiterapia
Mel
-Infecções Estafilocócicas/microbiologia
Infecção dos Ferimentos/microbiologia
Infecção dos Ferimentos/terapia
Distribuição Aleatória
Colágeno/análise
Interleucina-6/análise
Fator de Necrose Tumoral alfa/análise
Ratos Wistar
Modelos Animais
Interleucina-1beta/análise
Staphylococcus aureus Resistente à Meticilina/isolamento & purificação
Carga Bacteriana
Fibroblastos
Leucócitos
Limites: Animais
Masculino
Responsável: BR1.1 - BIREME


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Mello, J. R. B
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Id: biblio-1011330
Autor: Peter, C. M; Waller, S. B; Picoli, T; Osório, L. G; Zani, J. L; Meireles, M. C. A; Faria, R. O; Mello, J. R. B; Hubner, S. O; Lima, M; Fischer, G.
Título: Chemical and cytotoxic analyses of three varieties of Brazilian propolis (green propolis, jataí propolis and brown propolis) and its anti-Sporothrix brasiliensis in vitro activity / [Análises químicas e citotóxicas de três variedades de própolis brasileiras (própolis verde, própolis jataí e própolis marrom) e sua atividade in vitro anti-Sporothrix brasiliensis]
Fonte: Arq. bras. med. vet. zootec. (Online);71(3):819-827, May-June 2019. tab, graf.
Idioma: en.
Resumo: In this study, we described the antifungal activity of three Brazilian propolis extracts: brown, green and from jataí bees against Sporothrix brasiliensis. The extracts were obtained from ethanolic extraction and their chemical composition was determined by high-performance liquid chromatography coupled to mass spectrometry. The cellular toxicity was measured in MDBK (Madin-Darby Bovine Kidney) cells and quantified by the MTT assay (3- (4,5 dimethylthiazol-2yl -2,5-diphenyl-2H bromine tetrazolato). For antifungal activity, the minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) were determined by broth microdilution. The results showed that cell toxicity was not observed at lower concentrations (0.097 to 0.39μg/ml) for all extracts in comparison to cell control. Among the chemical compounds identified, caffeic acid, p-coumaric acid, chlorogenic acid, ferulic acid and rutin were quantified. In antifungal activity, green and jataí did not exhibit activity against the isolates (MIC and MFC greater than 0.78mg/ml). However, all isolates of S. brasiliensis were sensitive to brown propolis (MIC of 0.09 to 0.78mg/ml), including the standard strain (P<0.001). Among the Brazilian propolis studied, the brown propolis showed activity against the S. brasiliensis isolates and more studies should be undertaken in order to evaluate its promising use in the treatment of sporotrichosis.(AU)

Neste estudo, descreveu-se a atividade antifúngica de três extratos de própolis brasileiras: marrom, verde e de abelhas jataí (Tetragonisca angustula), contra Sporothrix brasiliensis. Os extratos foram obtidos de extração etanólica, e a sua composição química foi determinada por cromatografia líquida de alta eficiência, acoplada à espectrometria de massa. A toxicidade celular foi medida em células MDBK (Madin-Darby Bovine Kidney), avaliada por observação microscópica e quantificada pelo ensaio MTT (3- (4,5-dimetiltiazol-2-ilo -2,5-difenil-2H bromo tetrazolato). Para a atividade antifúngica, determinou-se a concentração inibitória mínima (CIM) e a concentração fungicida mínima (CFM) por meio de microdiluição em caldo. Os resultados mostraram que a toxicidade celular não foi observada em concentrações menores (0,097 a 0,39μg/ml). Entre os compostos químicos identificados, foram quantificados o ácido cafeico, ácido p-cumárico, ácido clorogênico, ácido ferúlico e a rutina. Na atividade antifúngica, as própolis verde e jataí não apresentaram atividade contra os isolados (CIM e CFM maior que 0,78mg/ml), porém todos os isolados de S. brasiliensis foram sensíveis à própolis marrom (CIM de 0,09 a 0,78mg/ml), incluindo a cepa padrão (P<0,001). Entre as própolis brasileiras estudadas, a marrom mostrou atividade contra S. brasiliensis, e mais estudos devem ser realizados para avaliar seu uso promissor no tratamento da esporotricose.(AU)
Descritores: Própole/análise
Própole/uso terapêutico
Sporothrix/isolamento & purificação
-Itraconazol/uso terapêutico
Farmacorresistência Fúngica
Apiterapia/veterinária
Antifúngicos/análise
Limites: Humanos
Animais
Responsável: BR68.1 - Biblioteca Virginie Buff D'Ápice


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Texto completo SciELO Cuba
Texto completo
Id: biblio-976167
Autor: Corona Carpio, Marcia Hortensia; López Verdecia, Charles Anthony; Duharte Escalante, Ana; Ramón Jimenez, Ruth; Tamayo Hernández, Yailen.
Título: Efectividad de la tintura de propóleos al 10 % en pacientes con estomatitis subprótesis / Effectiveness of 10 % propolis tinction in patients with subprosthesis stomatitis
Fonte: Medisan;22(9), nov.-dic. 2018. tab.
Idioma: es.
Resumo: Se efectuó un estudio de intervención terapéutica en 50 pacientes con estomatitis subprótesis, quienes acudieron a la consulta de prótesis de la Clínica Estomatológica Ramón Guevara Montano de Baracoa, provincia de Guantánamo, desde abril del 2015 hasta junio del 2016, con vistas a determinar la efectividad del tratamiento con tintura de propóleos al 10 por ciento en los afectados. Se conformaron 2 grupos: uno de estudio (A) y otro de control (B), con 25 integrantes cada uno; el primero fue tratado con propóleos y el segundo con medicina alopática (nistatina en suspensión). La evaluación se realizó a los 4, 8 y 12 días. Al finalizar la terapia se observó que en 100,0 por ciento de los pacientes del grupo A se eliminó la lesión; por tanto, esta alternativa terapéutica resultó efectiva. Se recomendó extender dicha aplicación a otras afecciones bucales.

A study of therapeutic intervention was carried out in 50 patients with subprosthesis stomatitis who went to the Prosthesis department of "Ramón Guevara Montano" Stomatological Clinic in Baracoa, Guantánamo province, from April, 2015 to June, 2016, aimed at determining the effectiveness of the treatment with 10 percent propolis tinction in the affected patients. Two groups were formed: a study group (A) and a control group (B), with 25 members each; the first one was treated with propolis tinction and the second with allopathic medicine (nystatin in suspension). The evaluation was carried out at 4.8 and 12 days. When concluding the therapy it was observed that in 100.0 percent of the patients of the group A the lesion was eliminated; therefore, this therapeutic alternative was effective. It was recommended to extend this procedure to other oral disorders.
Descritores: Própole/uso terapêutico
Estomatite sob Prótese/terapia
Candidíase/terapia
-Avaliação de Eficácia-Efetividade de Intervenções
Apiterapia
Mel
Limites: Humanos
Masculino
Feminino
Adolescente
Adulto
Pessoa de Meia-Idade
Idoso
Tipo de Publ: Artigo Clássico
Responsável: CU1.1 - Biblioteca Médica Nacional


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Id: biblio-910794
Autor: Martínez, Romina Paola.; Feldman, Jorge; Álvarez, Marcelo.
Título: Utilización de medicina complementaria en procesos degenerativos articulares / Use of complementary medicine in joint degenerative processes.
Fonte: Tandil; s.n; 2016. 39 p. ilus, tab.
Idioma: es.
Tese: Apresentada a Universidad Nacional del Centro de la Provincia de Buenos Aires para obtenção do grau de Especialista.
Resumo: En la clínica alopática vemos a diario el avance de nuevos tratamientos hacia diversas patologías. Sin embargo, se ha visto que en las terapias crónicas de enfermedades inflamatorias degenerativas asociadas a la edad del paciente, (gerontes) el margen terapéutico de sus medicamentos se torna cada vez más estrecho, debido a que con el paso del tiempo aparecen disfunciones orgánicas que limitan la aplicación de fármacos sintéticos, por sus efectos colaterales. Es en esta brecha donde la medicina complementaria comienza a jugar un papel importante en el arsenal terapéutico del médico veterinario. En esta tesina, se describirán tres herramientas terapéuticas dentro de las llamadas medicinas complementarias que se utilizan en la terapia de los procesos degenerativos del aparato osteoarticular y se comparará su efecto de acción con las drogas antiinflamatorias de síntesis que se usan habitualmente. Las terapias que se desarrollarán en este trabajo son: La acupuntura, la fitomedicina y la apiterapia a través de la aplicación de apitoxina.
Descritores: Acupuntura
Terapias Complementares
Artropatias
-Apiterapia
Argentina
Doença Crônica
Limites: Animais
Responsável: BR1.1 - BIREME


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Texto completo SciELO Chile
Texto completo
Id: lil-734617
Autor: Jantakee, Kanyaluck; Tragoolpua, Yingmanee.
Título: Activities of different types of Thai honey on pathogenic bacteria causing skin diseases, tyrosinase enzyme and generating free radicals
Fonte: Biol. Res;48:1-11, 2015. graf, tab.
Idioma: en.
Projeto: Chiang Mai University. Faculty of Science; . The Thailand Research Fund-Research and Researchers for Industry; . Bee Products Industry Co.
Resumo: BACKGROUND: Honey is a natural product obtained from the nectar that is collected from flowers by bees. It has several properties, including those of being food and supplementary diet, and it can be used in cosmetic products. Honey imparts pharmaceutical properties since it has antibacterial and antioxidant activities. The antibacterial and antioxidant activities of Thai honey were investigated in this study. RESULTS: The honey from longan flower (source No. 1) gave the highest activity on MRSA when compared to the other types of honey, with a minimum inhibitory concentration of 12.5% (v/v) and minimum bactericidal concentration of 25% (v/v). Moreover, it was found that MRSA isolate 49 and S. aureus were completely inhibited by the 50% (v/v) longan honey (source No. 1) at 8 and 20 hours of treatment, respectively. Furthermore, it was observed that the honey from coffee pollen (source No. 4) showed the highest phenolic and flavonoid compounds by 734.76 mg gallic/kg of honey and 178.31 mg quercetin/kg of honey, respectively. The antioxidant activity of the honey obtained from coffee pollen was also found to be the highest, when investigated using FRAP and DPPH assay, with 1781.77 mg FeSO4•7H2O/kg of honey and 86.20 mg gallic/kg of honey, respectively. Additionally, inhibition of tyrosinase enzyme was found that honey from coffee flower showed highest inhibition by 63.46%. CONCLUSIONS: Honey demonstrates tremendous potential as a useful source that provides anti-free radicals, anti-tyrosinase and anti-bacterial activity against pathogenic bacteria causing skin diseases.
Descritores: Apiterapia
Flavonoides/análise
Mel/análise
Monofenol Mono-Oxigenase
Staphylococcus aureus Resistente à Meticilina/efeitos dos fármacos
Fenóis/análise
Pólen/química
-Antibacterianos/farmacologia
Antioxidantes/farmacologia
Compostos de Bifenilo
Café/química
Recuperação de Fluorescência Após Fotodegradação
Flores/química
Radicais Livres/análise
Mel/classificação
Testes de Sensibilidade Microbiana
Monofenol Mono-Oxigenase/antagonistas & inibidores
Monofenol Mono-Oxigenase/efeitos dos fármacos
Picratos
Pólen/classificação
Dermatopatias/microbiologia
Dermatopatias/terapia
Preparações Clareadoras de Pele/farmacologia
Tailândia
Fatores de Tempo
Viscosidade
Tipo de Publ: Research Support, Non-U.S. Gov't
Responsável: CL1.1 - Biblioteca Central


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Texto completo SciELO Cuba
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Id: lil-675526
Autor: Ruiz Salvador, Ana Karelia; García Milián, Ana Julia; Jiménez López, Giset; Alfonso Orta, Ismary; Pérez Hernández, Bárbaro; Carrazana Lee, Armando.
Título: Farmacovigilancia de fitofármacos y apifármacos en Cuba durante 2006-2010 / Pharmacovigilance of phytomedicines and apimedicines in Cuba, 2006-2010
Fonte: Rev. cuba. plantas med;18(2):173-186, abr.-jun. 2013.
Idioma: es.
Resumo: Introducción: las plantas y los productos de la colmena han sido una importante fuente de medicinas durante un largo período, pero también pueden provocar reacciones adversas. Objetivo: caracterizar las reacciones adversas asociadas al uso de los fitofármacos y apifármacos que se comercializaron en Cuba en el período 2006-2010. Método: se realizó un estudio observacional, descriptivo y transversal. La muestra estuvo constituida por la totalidad de los reportes de sospechas de reacciones adversas a medicamentos, producidas por fitofármacos y apifármacos a la Unidad Coordinadora Nacional de Farmacovigilancia, durante el período de estudio. Resultados: la mayoría de los reportes de sospechas de reacciones adversas se distribuyeron en el sexo femenino (73,3 por ciento) y en el grupo etario de 31 a 60 años (52,5 por ciento). El ajo tintura y jarabe (13,4 por ciento), el Vimang® tableta y jarabe (9,7 por ciento), así como el eucalipto jarabe y tintura (6,6 por ciento) resultaron los fitofármacos más notificados, mientras que el propóleos tintura (3,4 por ciento) lo fue dentro de los apifármacos reportados. El sistema digestivo resultó el más afectado por las reacciones adversas, clasificadas mayormente de leves y probables. Conclusiones: la farmacovigilancia realizada a los fitofármacos y apifármacos en el período estudiado guarda relación con lo reportado en la literatura para estos productos

Introduction: plants and beehive products have been an important source of medicines for a long time, but they may also cause adverse reactions. Objective: characterize the adverse reactions associated with the use of phytomedicines and apimedicines sold in Cuba from 2006 to 2010. Method: a cross-sectional observational descriptive study was conducted. The sample consisted of all the reports on suspected adverse drug reactions caused by phytomedicines and apimedicines submitted to the National Pharmacovigilance Coordinating Unit during the study period. Results: most reports on suspected adverse reactions corresponded to the female sex (73.3 percent) and the 31-60 age group (52.5 percent). The phytomedicines most frequently reported were garlic tincture and syrup (13.4 percent), Vimang™ pills and syrup (9.7 percent), and eucalyptus syrup and tincture (6.6 percent), whereas the most frequently reported apimedicine was propolis tincture (3.4 percent). The digestive system was the most commonly affected by adverse reactions, which were mostly classified as mild or probable. Conclusions: pharmacovigilance of phytomedicines and apimedicines during the study period is consistent with the bibliographic information about the topic
Descritores: Apiterapia
Medicamentos Fitoterápicos
Responsável: CU1.1 - Biblioteca Médica Nacional



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