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Pesquisa : E02.190.388 [Categoria DeCS]
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Id: biblio-979923
Autor: Demarque, Denis.
Título: Homeopatia: Medicina de base experimental / Homeopathy: experimental Basic Medicine.
Fonte: Ribeirão Preto; Museu de Homeopatia Abrahão Brickmann; 2002. 363 p.
Idioma: pt.
Resumo: A presente obra aborda os principais conceitos, com enfoque no histórico desde Hipócrates, passando por diversos autores, por Hahnemann, até a atualidade em que viveu na França (1915-1999).
Descritores: Terapêutica/história
Métodos de Estudo de Matéria Médica
Doença Crônica
Homeopatia/história
-Isoterapia/história
Nosódios (Homeopatia)/história
Tipo de Publ: Bibliografia
Responsável: BR926.1 - Biblioteca Artur de Almeida Rezende Filho
BR926.1; WB930, D372h, 2002


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Id: biblio-1050039
Autor: Gupta, Jaya; Rao, M. Prakash; Raju, Kolli; Prasad, R V R; Arya, J S; Mondal, B K; Sadanandan, Gopinadhan; Singh, Mohan; Singh, Vikram; Nayak, Chaturbhuja; Pramanik, Abhishek; Kumar, Arvind; Roja, Varanasi.
Título: Management of early years of simple and mucopurulent chronic bronchitis with pre-defined Homoeopathic medicines ­ a Prospective Observational Study with 2-Years Follow-Up
Fonte: Int. j. high dilution res;18(3/4):47-62, 2019.
Idioma: en.
Resumo: Background Simple and mucopurulent chronic bronchitis (SMCB) is characterized by recurrent mucoid or mucopurulent expectoration in absence of localized suppurative disease. This observational open label study was undertaken to evaluate the effects of homeopathic medicine in SMCB. Methods 1902 patients were screened from 07 centres out of which 1305 were excluded. 597 patients were enrolled as per the inclusion and exclusion criteria. A total of 14 pre-defined homeopathic medicines were shortlisted for prescription after repertorizing the pathological symptoms of SMCB. Outcomes were assessed through chronic bronchitis symptom scale (CBSS) and FEV1/ FVC ratio with spirometry for over a period of two years. Appearance of any change (relief/ worse)/ status quo was immediately followed by placebo/ change in dilution/ change in remedy. Statistical analysis was done using SPSS version 20. Results: 532 patients were analyzed based on the intention to treat principle using last observation carry forward method. Mean CBS score reduced from 29.86±4.5 at baseline to 12.33±7.6 at completion of 2 years. Repeated measures ANOVA, at time points 0 (baseline), 3, 6, 9, 12 ,15, 18, 21 and 24 months, showed significant reduction in CBS scores [Wilk's Lambda 0.104, F=564, df 524; p=00001]. The FEV1 and FEV1/FVC was maintained within normal limits. 86% prescriptions included Lycopodium, Arsenicum album, Pulsatilla, Phosphorus, Stannum metallicum, Calcarea carbonica, Silicea, Bryonia alba. Conclusion: The result suggests effectiveness of homeopathic treatment in early years of SCMB patients. Controlled trials are warranted. (AU)
Descritores: Bronquite Crônica/terapia
Homeopatia
-Pulsatilla nigricans/uso terapêutico
Arsenicum Album/uso terapêutico
Calcarea Carbonica/uso terapêutico
Lycopodium clavatum/uso terapêutico
Phosphorus (Homeopatia)
Silicea Terra/uso terapêutico
Stannum Metallicum/uso terapêutico
Bryonia
Limites: Seres Humanos
Masculino
Feminino
Adulto
Meia-Idade
Tipo de Publ: Estudo Observacional
Responsável: BR926.1 - Biblioteca Artur de Almeida Rezende Filho


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Id: biblio-1046101
Autor: Stiefelmann, Henrique.
Título: Thesaurus homeopático / Homeopathic Thesaurus.
Fonte: São Paulo; Santos Editora; 2009. 424 p. tab, ilus.
Idioma: pt.
Resumo: Uma das maiores preocupações da prática homeopática foi com o grau de fiabilidade dos elementos colhidos durante uma entrevista e sua objetivação. Desde o início, procurávamos seguir as orientações de Hahnemann quanto à feitura do registro do caso (o record). Porém, mesmo após esse detalhamento caíamos nas rubricas repertoriais mais usuais. Esse vício de informação nos conduzia, salvo raríssimas exceções, assim chamados policrestos. A partir de 1986, comecei a sistematizar uma técnica, selecionando as palavras mais chamativas, qualificando -as, anotando sua frequência, correlacionando-as em conjuntos por analogias, sinonímia, antonímia, etc. Fazendo, enfim, combinações progressivas até chegar às intersecções dos conjuntos que permitem análise e tabulação. A partir desse instrumento, pude obter uma visão da totalidade que em geral, é desprezada no nosso trabalho cotidiano como homeopatas. Uma vez que essa técnica está em processo de desenvolvimento, não dispensamos o uso clássico da coleta de sintomas, hierarquização e repertorização, com suas variantes. (AU)
Descritores: Anamnese Homeopática
Repertorização
Métodos de Estudo de Matéria Médica
Estrutura Repertorial
Homeopatia
Responsável: BR926.1 - Biblioteca Artur de Almeida Rezende Filho
WB934.3; S855, 2009. São Paulo


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Id: biblio-982049
Autor: Rocco, Vincenzo; Bellis, Immacolata De; Aversa, Andrea Antonio; Melodia, Carlo; Rusciano, Flora; Sabatino, Giuseppina; Rodríguez, Adele Alma.
Título: Tendencias miasmáticas en las patologías autoinmunes / Miasmatic tendencies in autoimmune pathologies
Fonte: Homeopatia Méx;86(706):5-12, ene.-feb. 2017. ilus, tab, graf.
Idioma: es.
Resumo: Desde los años sesenta, los homeópatas, junto con los físicos biomédicos, generalmente han reconocido al ensayo de control doble ciego aleatorio (ECA) como el "estándar de oro" para establecer la eficacia en una intervención clínica. Sin embargo, la profesión homeopática se ha mostrado ambivalente respecto a la incorporación del modelo ECA para la validación interna de los medicamentos homeopáticos. Este texto muestra importantes elementos del ECA, como la evaluación ciega, la aleatoriedad y la inferencia estadística, examinando algunos de los elementos históricos y científicos acerca de su inclusión en las experimentaciones homeopáticas. (AU)

Since the 1960s, homeopaths, along with biomedical physicians, have generally acknowledged the double-blind, randomized, controlled trial (RCT) as the "gold standard" for establishing the efficacy of a clinical intervention. The homoeopathic profession has, however, been ambivalent about the incorporation of the RCT model for the internal validation of homoeopathic medicines. This paper looks at important components of the RCT such as blind assessment, randomization and statistical inference and examines some of the historical and scientific issues about their adoption for homoeopathic provings. (AU)
Descritores: Doenças Autoimunes
Miasma em Homeopatia
Psora em homeopatia
Sicose em Homeopatia
Homeopatia
Responsável: BR926.1 - Biblioteca Artur de Almeida Rezende Filho


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Id: biblio-1050038
Autor: Wakte, Mitesh Santosh; Patel, Mugdhakumari R; Gowda, Sharda Shankar; Bhadoria, Suraj Singh; Joshi, Niranjan; Jadhav, Arun Bhargav; Patil, Aditya Dilipkumar.
Título: A review on preclinical studies conducted with Homeopathic medicine Cephalandra indica as an Anti-hyperglycemic agent
Fonte: Int. j. high dilution res;18(3/4):35-46, 2019.
Idioma: en.
Resumo: Background ­ Diabetes Mellitus a metabolic disorder affects the secretion of insulin from pancreas leading to hyperglycemia, if uncontrolled leads to complications triggered by free radical formed after oxidative stress. Homeopathic medicine Cephalandra Indica has shown antidiabetic activity in various potencies performed on preclinical studies on diabetic rat model. The present review highlights the pharmacological profile of homeopathic preparations Cephalandra Indica on preclinical studies and calculating the probable human equivalent dosage from preclinical studies for the pilot studies. Method ­ Articles published between January 1988 and December 2018 was included in review. Databases like PubMed ­ Medline, Google scholar were used for collecting the articles. Keywords like 'Homeopathy' or 'Homoeopathy', 'Invitro', 'Invivo' and 'Cephalandra Indica' were used. SABEH criteria were implemented for assessing methodology quality of articles. Results ­ Seven full text articles were included in review which had six Invivo studies and one Invitro study. This review article provided the scientific validation of high diluted homeopathic medicines pharmacological activity of Cephalandra Indica and probable mechanism of action confirmed through preclinical studies. Conversion of dosage from animal model to human dosage for pilot studies has been hypothetically proposed. Conclusion ­ Homeopathic medicine Cephalandra Indica has a therapeutic and safety profile with no toxicity observed in preclinical studies. The proposed hypothesis of conversion of dosage needs to be validated for further studies. (au)
Descritores: Diabetes Mellitus
Avaliação Pré-Clínica de Medicamentos
Homeopatia
-Bryonia
Responsável: BR926.1 - Biblioteca Artur de Almeida Rezende Filho


  6 / 1580 LILACS  
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Id: biblio-1050037
Autor: Konar, Atheni; Sarkar, Tandra; Sukul, Nirmal Chandra; Sukul, Abirban; Chakraborty, Indrani; Ray, Sriparna.
Título: High and ultra low concentrations of Mercuric chloride initiate their specific action on binding sites of invertase and modify its interaction with sucrose
Fonte: Int. j. high dilution res;18(3/4):19-34, 2019.
Idioma: en.
Resumo: Background: Mercuric chloride is known to inhibit the activity of enzymes. It is used in homeopathy at ultra low concentration (ULC) and is known as Mercurius corrosivus (Merc cor). ULCs of Merc cor are reported to promote enzyme activity. Objective: To see whether the mother tincture (θ) of Merc cor and its ULCs interact with an enzyme invertase at its binding sites and influence enzyme's action on its substrate sucrose. Methods: Merc cor θ (0.15 M HgCl2) was diluted with deionized and distilled (DD) water 1:100 and succussed 10 times to prepare Merc cor 1 cH or 1st potency. This potency was further diluted and succussed in 200 and 1000 steps to prepare 200cH and 1000cH potencies, respectively. Merc cor 200 cH and 1000cH were prepared in 90% ethanol. The two potencies and blank 90% EtOH were diluted with DD water 1:1000 to minimize ethanol content to a negligible amount 0.09%. The control was DD water (0.99g/M). The drugs, EtOH and water control were mixed separately with 0.037 mM invertase in DD water. Using an isothermal calorimetry (ITC) instrument the substrate sucrose (65mM) was injected at 2 µl every 2 min into 300 µl invertase solution 20 times at 25 0C. Molecular modeling study was done to predict possible binding sites and nature of binding between the enzyme and HgCl2, and between the enzyme and water. Potencies after dilution are virtually water. Fluorescence spectra of invertase (4µM) mixed with drug/control solutions were also obtained to see the effect of drugs on protein folding. Results: Thermodynamic parameters like binding constant (K), change in enthalpy(ΔH), entropy(ΔS) and Gibbs free energy(ΔG) showed marked variation in treatment effects on the enzyme. Molecular modeling study also shows variation in binding between invertase and HgCl2, and between invertase and water. Fluorescence spectra show variation in quenching related to different treatments. Conclusion: Merc cor mother tincture and its potencies interact at different binding sites of invertase and modify the enzyme's action on sucrose. So, potencies act as modulators of ligand, sucrose. Drug solutions induce conformational changes in the enzyme. (au)
Descritores: Sacarose
Sítios de Ligação
Modelos Moleculares
Baixas Potências
beta-Frutofuranosidase
Homeopatia
Cloreto de Mercúrio
Responsável: BR926.1 - Biblioteca Artur de Almeida Rezende Filho


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Id: biblio-1050032
Autor: GIRI.
Título: Proceedings of the XXXIII GIRI meeting
Fonte: Int. j. high dilution res;18(2), 2019.
Idioma: en.
Descritores: Homeopatia
Tipo de Publ: Congressos
Responsável: BR926.1 - Biblioteca Artur de Almeida Rezende Filho


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Id: biblio-1050029
Autor: Shah, Rajesh; Talele, Gitanjali.
Título: Preparation of Cancer Nosodes from specific cancer tissues
Fonte: Int. j. high dilution res;18(1):28-34, 2019.
Idioma: en.
Resumo: Nosodes are ultra-dilute preparations made from diseased tissues or organisms used in homeopathy since 1830, more frequently used since 1880. Carcinosin is a commonly used nosode prepared over 100 years ago from cancer tissues in the last part of the nineteenth century, of which the exact scientific information on the histopathological characterization of the source material is not available. The current therapeutic indications of Carcinosin have been largely empirical and clinically derived. In such a scenario, understanding the paramount importance of the Cancer nosode, it's revamping in the light of current scientific knowledge has been identified by the author. Specific cancerous tissue samples were sourced for nosode preparation. Identified pieces of tissue were histopathologically diagnosed, thoroughly washed, quantified and triturated with powder of Saccharum lactis to prepare decimal potencies, as per standard method suggested in the Homoeopathy Pharmacopoeia of India. Centesimal potencies were prepared using electromechanical potentizer, documenting the force parameters. The Cancer nosodes from specific cancer tissues were prepared in a systematic manner, which could be used for research as well as in clinical practice. The author has attempted scientific preparation of new Cancer nosodes making them available to the profession. On similar lines, more of cancer tissues could be explored for making other nosodes. (AU)
Descritores: Carcinosinum/uso terapêutico
Nosódios (Homeopatia)
Homeopatia
Neoplasias
Responsável: BR926.1 - Biblioteca Artur de Almeida Rezende Filho


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Id: biblio-1050028
Autor: Shah, Rajesh.
Título: Evaluating the anticancer effects of high-dilution preparations of carcinogens such as HIV virus, Hepatitis C virus, Ethanol and Cancer tissues in in-vitro models
Fonte: Int. j. high dilution res;18(1):12-27, 2019.
Idioma: en.
Resumo: Background Cancer is one of the leading causes of mortality. The recent experiments with high-diluted preparations have shown anticancer effects in in-vitro and vivo models. The fundamental principle of homeopathy suggests that the substances capable of producing certain diseases may have a capacity to alter the same disease if used in the ultra-dilute-potentized form. This hypothesis led certain carcinogens for examining their potential anti-cancer efficacy. Method Sulforhodamine B assay is useful in determining the cytotoxicity in cell-based studies in evaluating anticancer agents. The protocol involved preparation of homeopathy dilutions, incubation of cells with homeopathy dilutions, SRB binding, and measurement of absorbance. Cells were treated with 30 potencies of HIV nosode, Hepatitis C nosode, Carcinosin, Cancer nosode, and Ethanol along with positive control (Adriamycin). The preparations were tested in HeLa, HepG2, A549, MCF 7, T 24, Jurkat, SCC 40, and HL-60 cell-lines. Results The homeopathic preparations have shown the anticancer activity measured as percentage growth inhibition. All the homeopathy preparations studied, exhibited anticancer activity on HeLa, HepG2, A 549, T 24, and HL-60 cells. Carcinosin showed the anticancer activity on the SCC 40 cells. Hepatitis C nosode, Carcinosin, and Cancer nosode have shown the anticancer activity on breast cancer cell line MCF-7. None of the preparations exhibited anticancer activity on Human Leukemia Cell Line. Conclusion High-dilution, potentized preparations of certain carcinogens have demonstrated anti-cancer, cytotoxic effects in the cell-line model, supporting the rationale of the fundamental homeopathic principle the Law of Similars, opening windows to its wider applications in healthcare. (AU)
Descritores: Nosódios (Homeopatia)
Homeopatia
Neoplasias
-HIV
Hepatite C
Responsável: BR926.1 - Biblioteca Artur de Almeida Rezende Filho


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Id: biblio-1050013
Autor: Moraes, Livia Cristina Cavalher Atz de Vilhena; Casali, Vicente Wagner Dias; Barros, João Nabuco Galvão de.
Título: Increase in growth of eucalyptus seedlings with application of homeopathic preparations
Fonte: Int. j. high dilution res;17(3/4):58-62, 2018.
Idioma: en.
Resumo: The use of less impacting techniques in agricultural systems is the global trend, so the use of homeopathic preparations on these systems has been studied as ecologically sound technology. This study had the object to study the interaction between the homeopathic preparations and the development of Eucalyptus urophylla S. T. Blake seedlings and was conducted from May 2007 to July 2007, in the greenhouse of the Department of Plant Science at the Federal University of Viçosa, MG, Brazil. Applications were made in one-day intervals and preparations utilized were Phosphorus, Calcarea carbonica, Kali muriaticum, Magnesia carbonica, all in potencies 3CH and 12CH and the controls were water and alcohol 3CH. Parameters of seedlings quality were measured in different times during the experiment, up to the end. Kali muriaticum 12CH promoted increased root length of approximately 55% compared to the water control. Phosphorus 3CH differed from other treatments considering the total green mass. The homeopathic preparations Phosphorus 3CH and Kali muriaticum 12CH increased the root growth, in relation to controls. The responses obtained with the application of Phosphorus 3CH indicate the viability of its agronomic use to increase of the root capacity of absorbing elements, as much as necessary for the plant growth. (AU)
Descritores: Altas Potências
Eucalyptus
Agricultura Orgânica
Homeopatia
-Calcarea Carbonica
Kali Muriaticum
Magnesia Carbonica
Phosphorus (Homeopatia)
Responsável: BR926.1 - Biblioteca Artur de Almeida Rezende Filho



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