Base de dados : LILACS
Pesquisa : E04.525.160 [Categoria DeCS]
Referências encontradas : 11 [refinar]
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Fotocópia
Aguiar, Paulo Henrique Pires de
Texto completo
Id: biblio-869760
Autor: Aguiar, Paulo Henrique Pires de; Rodrigues, Luciana; Estevão, Iracema; Janoti, Cristiani; Sacoman, Debora; Simm, Renata Faria; Frigeri, Thomas; Simis, Samuel.
Título: La Insulectomía podría ser un abordaje ideal para crisis insulares y peri-insulares? / Insulectomy for insular and peri-insular seizures could be an ideal and safe approach?
Fonte: Rev. chil. neurocir;42(2):107-110, nov. 2016. ilus.
Idioma: en.
Resumo: La insulectomía es una técnica microquirúrgica establecida para el tratamiento de la epilepsia refractaria al tratamiento farmacológico. El origen insular de la epilepsia es inusual, sin embargo, con la investigación a través de electrodos híbridos este tipo de epilepsia ha incrementado su diagnóstico. Los autores hacen hincapié en las funciones insulares, así como los puntos de referencia anatómicos para la cirugía. Se discuten las principales complicaciones y las bases fisiológicas para las indicaciones de cirugía.

Insulectomy is an established microsurgical technique for treatment of insular epilepsy refractory to clinical management. The insular origin of epilepsy is unusual, however with depth investigation through hybrids electrodes such kind of epilepsy is increasing its diagnosis. The authors emphasizes the insular functions as well as the anatomical landmarks for surgery. The main complications are discussed and physiological basis for indications.
Descritores: Descorticação Cerebral
Córtex Cerebral/anatomia & histologia
Córtex Cerebral/cirurgia
Córtex Cerebral/fisiologia
Eletrodos
Eletroencefalografia/métodos
Epilepsia do Lobo Temporal/cirurgia
-Resistência a Medicamentos
Microcirurgia/métodos
Limites: Humanos
Tipo de Publ: Revisão
Responsável: CL2.1 - Biblioteca de Medicina


  2 / 11 LILACS  
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Fotocópia
Texto completo SciELO Brasil
Texto completo
Id: lil-727667
Autor: Shang, J.L.; Cheng, Q.; Yang, W.F.; Zhang, M.; Cui, Y.; Wang, Y.F..
Título: Possible roles of COX-1 in learning and memory impairment induced by traumatic brain injury in mice
Fonte: Braz. j. med. biol. res = Rev. bras. pesqui. méd. biol;47(12):1050-1056, 12/2014. graf.
Idioma: en.
Resumo: People who suffer from traumatic brain injury (TBI) often experience cognitive deficits in spatial reference and working memory. The possible roles of cyclooxygenase-1 (COX-1) in learning and memory impairment in mice with TBI are far from well known. Adult mice subjected to TBI were treated with the COX-1 selective inhibitor SC560. Performance in the open field and on the beam walk was then used to assess motor and behavioral function 1, 3, 7, 14, and 21 days following injury. Acquisition of spatial learning and memory retention was assessed using the Morris water maze on day 15 post-TBI. The expressions of COX-1, prostaglandin E2 (PGE2), interleukin (IL)-6, brain-derived neurotrophic factor (BDNF), platelet-derived growth factor BB (PDGF-BB), synapsin-I, and synaptophysin were detected in TBI mice. Administration of SC560 improved performance of beam walk tasks as well as spatial learning and memory after TBI. SC560 also reduced expressions of inflammatory markers IL-6 and PGE2, and reversed the expressions of COX-1, BDNF, PDGF-BB, synapsin-I, and synaptophysin in TBI mice. The present findings demonstrated that COX-1 might play an important role in cognitive deficits after TBI and that selective COX-1 inhibition should be further investigated as a potential therapeutic approach for TBI.
Descritores: Lesões Encefálicas/complicações
Córtex Cerebral/lesões
Ciclo-Oxigenase 1/fisiologia
Inibidores de Ciclo-Oxigenase/uso terapêutico
Aprendizagem/efeitos dos fármacos
Transtornos da Memória/tratamento farmacológico
Pirazóis/uso terapêutico
-Western Blotting
Fator Neurotrófico Derivado do Encéfalo/metabolismo
Descorticação Cerebral
Ciclo-Oxigenase 1/metabolismo
Modelos Animais de Doenças
Dinoprostona/análise
Dinoprostona/metabolismo
Ensaio de Imunoadsorção Enzimática
Hipocampo/metabolismo
/sangue
INTERLEUKIN-ABDOMEN, ACUTE/sangue
Aprendizagem em Labirinto/efeitos dos fármacos
Transtornos da Memória/etiologia
Transtornos da Memória/metabolismo
MICE, INBRED CABDOMENABDOMINAL INJURIESBL
Proteínas Proto-Oncogênicas c-sis/metabolismo
Recuperação de Função Fisiológica/efeitos dos fármacos
Sinaptofisina/análise
Sinaptofisina/metabolismo
Limites: Animais
Responsável: BR1.1 - BIREME


  3 / 11 LILACS  
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Fotocópia
Id: lil-404781
Autor: Pomata, Hugo.
Título: Functional hemispherectomy variant a report of twenty one cases / Functional hemispherectomy variant a report of twenty one cases
Fonte: Rev. argent. neurocir;18(supl.2):38-43, ago. 2004. ilus.
Idioma: es.
Resumo: Objective and importance: Although Rasmussen´s hemispherectomy is a proven effective technique, the reduction in surgical time and in blood volume los during its performance is crucial. This is achieved by means of the tecnichal variant intended to disconnect instead of to remove the temporal lobe. Clinical representation: We present 21 children operated between 1997 and 2004 in whom a functional hemisfactory (FH) variant was performed. The clinical manifestations included the following crises: hemianopsia, versive crises, abscences, CPC and tonic crises, with secondary generalization in some of the children. Intervention: The proposed variant is a sort of combination of Rasmussen´s hemispherectomy and Delalande´s hemispherectomy, involving disconnection and isolation of the temporal lobe. This is achieved at cortical level by prolonging the incision of the mesial aspect of the occipital lobe by intraventricular route is extended towards the fornix to reach the free border of the cerebellar tentorium. The juncture of both incisions disconnects the neocortex from the temporal lobe, as well as the parahippocampal gyrus and the hippocampus itself. Since aprevious complete callosotomy, a temporal stem section and amigdala suction had been performed, the temporal lobe remains in situ, but nonfunctional. Conclusion: It is the autor conviction that Rasmussen´s hemipherectomy is a valid procedure given its proven efficacy. We believe that the proposed technical variant is particularly useful for neurosurgeons that are in training in the field of epilepsy surgery, as a priori stage to the use of more restricted disconnecting techniques
Descritores: Descorticação Cerebral
Encefalite
Neurocirurgia
Lobo Temporal
Responsável: AR423.1 - Biblioteca


  4 / 11 LILACS  
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Fotocópia
Id: lil-343432
Autor: Cuba Rodriguez, Juan Manuel.
Título: Neuroplasticidad y adaptación funcional del sistema nervioso: aproximación a la anatomía funcional del tronco cerebral / Neuroplasticity and funcional supply of nervous system: aproximation to brain stem funcional anatomy
Fonte: Rev. neuropsiquiatr;57(2):109-122, jun. 1994. ilus.
Idioma: es.
Resumo: Se revisa las últimas investigaciones sobre plasticidad neuronal, en relación con el crecimiento dendrítico y la regeneración de los cilindroejes en la suplencia funcional de la corteza cerebral y el sistema estriado en la reorganización de las funciones superiores. Se recuerda la importancia de las funciones del tronco cerebral en el hombre y se propone una nueva sistematización: el Arqui-tronco, en relación a sus funciones vegetativas, el Paleo-tronco, en relación con el hombre y su medio ambiente y el Neo-tronco, cuyas funciones aún desconocemos. En fin, se presenta la observación de una paciente decorticada mediante la evaluación clínica y la resonancia magnética que, sin embargo, mantiene sus funciones de percepción y elaboración de juicios y criterios; la expresión de estos la ejecuta mediante gritos.
Descritores: Adaptação Fisiológica
Sistema Nervoso Central
Regeneração Nervosa/fisiologia
-Descorticação Cerebral
Limites: Humanos
Adulto
Feminino
Tipo de Publ: Revisão
Relatos de Casos
Responsável: PE1.1 - Oficina Universitária de Biblioteca


  5 / 11 LILACS  
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Fotocópia
Id: lil-207692
Autor: Riarte, José Enrique.
Título: Alteración de la conciencia en el paciente crítico en coma: protocolo de seguimiento razonado / Conscience alteration at critical patients in coma: records of a reasoned follow - up
Fonte: Rev. med. Tucumán;1(4):175-98, jul.-ago. 1994. ilus, tab, graf.
Idioma: es.
Descritores: Coma/diagnóstico
Coma/etiologia
Consciência
Estado Vegetativo Persistente
Protocolos Clínicos/normas
Anormalidades do Sistema Respiratório
-Afasia Acinética
Descorticação Cerebral
Respiração de Cheyne-Stokes
Fossa Craniana Posterior/lesões
Estado de Descerebração
Movimentos Oculares
Escala de Coma de Glasgow
Hipotálamo Posterior/lesões
Hiperventilação
Miose
Limites: Masculino
Feminino
Humanos
Responsável: AR1.1 - Biblioteca Rafael Herrera Vegas


  6 / 11 LILACS  
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Fotocópia
Brandäo, M. L
Id: lil-83140
Autor: Bagri, A; Tomaz, C; Brandäo, M. L; Carrive, P.
Título: Increased susceptibility of detelencephalated rats to audiogenic seizures induced by microinjection of bicuculline into the inferior colliculus
Fonte: Braz. j. med. biol. res = Rev. bras. pesqui. méd. biol;22(11):1361-70, 1989. ilus.
Idioma: en.
Resumo: The participation of telencephalic forebrain structures in the induction of audiogenic seizure (AGS) susceptibility and in the behavioral expression of AGS was investigated in rats. Rats that were initially susceptible (N = 12) or non-susceptible (N = 28) to audiogenic seizure were surgically detelencephalated. A unilateral microinjection of a low dose (30 pmol) of the GABA antagonist bicuculline methiodide (BM) was applied to the inferior colliculus (IC) before the animals were exposed to a 120-dB acoustic stimulus. All susceptible rats still exhibited all components of audiogenic seizure after removal of the telencephalon. After BM microinjection, a higher incidence (66% vs 41%) and shorter latencies (6-20 s vs 9-55) s) of occurrence of tonic seizures were observed in the detelencephalated non-susceptible rats when compared to non-operated non-susceptible rats(N = 12). These results suggest that the induction of the behavioral expression of audiogenic seizures issubserved by brain stem neuronal networks but does not require the telencephalon and that telencephalic structures may exert control over audiogenic seizures by inhibiting IC cells through GABAergic neurons
Descritores: Bicuculina/farmacologia
Descorticação Cerebral
Colículos Inferiores/fisiologia
Convulsões/etiologia
-Estimulação Acústica
Córtex Cerebral/patologia
Ratos Endogâmicos
Telencéfalo/fisiologia
Limites: Ratos
Animais
Masculino
Responsável: BR26.1 - Biblioteca Central


  7 / 11 LILACS  
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Fotocópia
Id: lil-75239
Autor: López Jiménez, M; Valença, M. M; Moreira, A. C; Rodrigues, J. Antunes.
Título: Ether and immobilization stress effects on pituitary adrenal function in hemidecorticate rats
Fonte: Braz. j. med. biol. res = Rev. bras. pesqui. méd. biol;22(6):779-82, June 1989. ilus.
Idioma: en.
Conferência: Apresentado em: Annual Meeting of the Federaçäo de Sociedades de Biologia Experimental, 4, Caxambu, June 28-July 2, 1989.
Projeto: CNPq; . CAPES; . AIEA.
Resumo: Hemidecortication (HD) (left cerebral hemisphere) performed in rats with the aim of analyzing the modulating effect of the cerebral cortex on the hypothalamic-pituitary-adrenal axis. Corticosterone release induced either by or immobilization stress was evaluated in control (C) and HD rats. The percentage increase in corticosterone was greater in HD than in C rats after 15 min of ether stress (HD = 142%, C = 50%) and after 60 min of immobilization stress (HD = 197%, C = 126%). An in vitro test showed that the release of ACTH induced by corticotropin releasing hormone (CRH) from hemipituitary fragments from HD rats was not different from that in control rats. These results suggest an inhibitory effect of the cerebral cortex on the hypothalamus which may modulate the secretion of corticoptropin releasing peptides
Descritores: Descorticação Cerebral
Éter/farmacologia
Sistema Hipófise-Suprarrenal/fisiologia
Estresse Fisiológico/fisiopatologia
-Hormônio Adrenocorticotrópico/metabolismo
Corticosterona/metabolismo
Restrição Física
Responsável: BR26.1 - Biblioteca Central


  8 / 11 LILACS  
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Fotocópia
Id: lil-73513
Autor: Matushita, Hamilton; Velasco, Octavio Luis Perez; Nakagawa, Edison J; Almeida, Gilberto Machado de.
Título: Hemisferectomia: modificaçäo técnica / Hemisferectomy: a techinical modification
Fonte: Arq. bras. neurocir;7(4):237-41, dez. 1988. ilus.
Idioma: pt.
Resumo: Os autores relatam uma modificaçäo técnica nas hemisferectomias totais, com intuito de prevenir os sangramentos tardios e distorçöes cerebrais
Descritores: Descorticação Cerebral/métodos
-Descorticação Cerebral/efeitos adversos
Hemorragia Cerebral/prevenção & controle
Craniotomia/métodos
Hemossiderose/etiologia
Hemossiderose/prevenção & controle
Limites: Humanos
Responsável: BR1.1 - BIREME


  9 / 11 LILACS  
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Fotocópia
Id: lil-67482
Autor: Tomaz, C; Okada, C. T; Faria, M. C. F. de; Castreghini, J. L.
Título: Swimming escape learning in rats with telencephalic lesions
Fonte: Braz. j. med. biol. res = Rev. bras. pesqui. méd. biol;22(1):61-4, 1989. tab.
Idioma: en.
Projeto: FAPESP; . CNPq; . FAPESP.
Resumo: Experiments were conducted to determine whether rats having unilateral or bilateral ablation of either the neocortex or telencephalon can learn to escape from a tank of water by climbing a platform. Hemi - or bilaterally decorticated rats were able to learn the swimming escape task, the same being observed for hemidetelencephalated rats. Fully detelencephalated rats, however, did not exhibit this capability. These results show that integrity of one the cerebral hemispheres is necessary in order to allow swimming escape learning
Descritores: Aprendizagem da Esquiva
Descorticação Cerebral
Reação de Fuga
Telencéfalo/fisiologia
-Córtex Cerebral/patologia
Natação
Responsável: BR26.1 - Biblioteca Central


  10 / 11 LILACS  
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Fotocópia
Merzel, J
Id: lil-63589
Autor: Munhoz, C. O. C; Tosello, D. O; fernandes, G. A; Merzel, J.
Título: Thyroid function in hemidecorticate rats
Fonte: Braz. j. med. biol. res = Rev. bras. pesqui. méd. biol;21(5):949-55, 1988. tab.
Idioma: en.
Projeto: FAPESP; . CNPq.
Resumo: 1. Throid function was evaluated in hemidecorticate (HD) and control (C) rats by determining serum T3 and T4 levels and the development of incisors and mandibles and through analysis of various histological features of the thyroid such as follicle size, colloid droplet content and [3H] - glycine uptake by follicular cells. 2. HD animals presented normal levels of circulating T3 but significantly lower T4 levels. 3. There was slight atrophy of the gland in HD animals and fewer colloid droplets were present in the cytoplasm of the follicular cells in this group, indicating a reduction in the breakdown of thyroglobulin. [3H] - glycine uptake by HD indicated that rate of thyroglobulin biosynthesis was not altered in the experimental animals. 4. the growth of mandibles (weight) and incisors (weight and lenght) was reduced in HD compared to the control animals. 5. These results suggest that hemidecortication causes mild hypothyroidism (trophoprivic type) probably by affecting hypothalamic function
Descritores: Descorticação Cerebral
Glândula Tireoide/fisiologia
Incisivo/crescimento & desenvolvimento
Mandíbula/crescimento & desenvolvimento
Tiroxina/sangue
Tri-Iodotironina/sangue
-Glândula Tireoide/patologia
Limites: Ratos
Animais
Responsável: BR26.1 - Biblioteca Central



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