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Id: lil-445718
Autor: Radrigán, Francisco.
Título: Tratamiento médico de la artrosis (osteoartritis) de rodilla en el anciano / Medical treatment of arthrosis (osteoarthritis) of knee in the elderly
Fonte: Rev. chil. reumatol;20(2):73-80, 2004. tab.
Idioma: es.
Descritores: Osteoartrite do Joelho/terapia
-Fatores de Risco
Osteoartrite do Joelho/epidemiologia
Sinais e Sintomas
Limites: Humanos
Idoso
Responsável: CL1.1 - Biblioteca Central


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Id: lil-445712
Autor: Riedemann, Pablo.
Título: Afecciones reumatológicas del adulto mayor / Rheumatologic diseases in elderly
Fonte: Rev. chil. reumatol;20(2):45-50, 2004. tab, graf.
Idioma: es.
Descritores: Doenças Reumáticas/epidemiologia
Envelhecimento
-ANCIANOS DE ACETABULARIA ANOS Y MAS
Chile
Comorbidade
Fatores Etários
Fatores de Risco
Incidência
Prevalência
Limites: Humanos
Adulto
Pessoa de Meia-Idade
Responsável: CL1.1 - Biblioteca Central


  3 / 26998 LILACS  
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Id: lil-640262
Autor: Camargo, Bruna Luz Custódio; Domingues, Thaísa Consorte; Niji, Vanessa Miguel; Nai, Gisele Alborghetti.
Título: Comparison between the concentration of mast cells and risk criteria of malignancy in intestinal adenomas
Fonte: J. coloproctol. (Rio J., Impr.);32(1):26-33, Jan.-Mar. 2012. graf, ilus.
Idioma: en.
Resumo: Intestinal adenomas are benign neoplasms that present a risk of malignancy associated with three independent characteristics: the polyp size, the histological architecture and the severity of epithelial dysplasia (or atypia). Current evidence suggests that mast cells (CM) contribute to the tumorigenesis of colorectal carcinomas. Objective: Compare the concentration of CM in intestinal adenomas and risk criteria for malignancy in these tumors (size, histological type and degree of cellular atypia). METHODS: We conducted a retrospective study with 102 anatomopathological reports of intestinal adenoma excision. We selected paraffin blocks with the central area of the tumor. The CM were stained with toluidine blue. RESULTS: In most cases (89.2%, n=91), the mast cells concentration (MC) was less than 6 CM/10 high power field (HPF) (p=0.0001). Most adenomas, regardless of their histological type, showed 0 CM/10 HPF (p=0.083). In most adenomas, regardless of their size, MC was 0 CM/10 HPF (p=0.665). Presence or absence of atypia was associated, in most cases, with MC of 0 CM/10 HPF (p=0.524). Conclusion: This study did not show association between the MC and histological type, size or presence of atypical cells in intestinal adenomas. (AU)

Adenomas intestinais são neoplasias benignas que apresentam risco de malignização relacionado a três características independentes: o tamanho do pólipo, a arquitetura histológica e a gravidade da displasia (ou atipia) epitelial. Evidências atuais sugerem que os mastócitos contribuem para a tumorigênese do carcinoma colorretal. OBJETIVO: Analisar comparativamente a concentração de mastócitos em adenomas intestinais e os critérios de risco para malignização nesses tumores (tamanho, tipo histológico e grau de atipia celular). Métodos: Realizou-se um estudo retrospectivo, com seleção de 102 laudos anatomopatológicos de exérese de adenoma intestinal. Foram selecionados os blocos de parafina com a área central da neoplasia para a realização da coloração de azul de toluidina para evidenciar os mastócitos. RESULTADOS: Na maioria dos casos (89,2%, n=91) a concentração de mastócitos (CM) foi menor que 6 mastócitos/10 campos de grande aumento (CGA) (p=0,0001). A maioria dos adenomas, independente do tipo histológico, mostrou 0 mastócito/10 CGA (p=0,083). A maioria dos adenomas, independentemente do tamanho, tinha CM de 0 mastócito/10 CGA (p=0,665). A presença ou a ausência de atipias esteve associada, na maioria dos casos, a CM de 0 mastócito/10 CGA (p=0,524). CONCLUSÃO: Este estudo não mostrou associação entre a concentração de mastócitos e tipo histológico, tamanho ou presença de atipias celulares nos adenomas intestinais. (AU)
Descritores: Adenoma
Fatores de Risco
Mastócitos
-Neoplasias Intestinais/patologia
Neoplasias Intestinais/epidemiologia
Limites: Humanos
Masculino
Feminino
Adulto
Pessoa de Meia-Idade
Idoso
Idoso de 80 Anos ou mais
Responsável: BR545.3 - Biblioteca ICBS


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Id: biblio-1249289
Autor: Yu, Holly; Flaster, Nestor; Casanello, Adrian Lopez; Curcio, Daniel.
Título: Assessing risk factors, mortality, and healthcare utilization associated with Clostridioides difficile infection in four Latin American countries
Fonte: Braz. j. infect. dis;25(1):101040, jan., 2021. tab, graf.
Idioma: en.
Resumo: ABSTRACT Background: Clostridioides difficile infection (CDI) is the most common cause of healthcare-associated infections in Western countries. Risk factors, mortality, and healthcare utilization for CDI in Latin America are poorly understood. This study assessed risk factors and burden associated with nosocomial CDI in four Latin American countries. Methods: This retrospective, case-control study used databases and medical records from 8 hospitals in Argentina, Brazil, Chile, and Mexico to identify nosocomial CDI cases from 2014 − 2017. Cases were patients aged ≥18 years with diarrhea and a positive CDI test ≥72 h after hospital admission. Two controls (without diarrhea; length of hospital stay [LOS] ≥3 days; admitted ±14 days from case patient; shared same ward) were matched to each case. CDI-associated risk factors were assessed by univariate and multivariable analyses. CDI burden (LOS, in-hospital mortality) was compared between cases and controls. Results: The study included 481 cases and 962 controls. Mean age and sex were similar between cases and controls, but mean Charlson comorbidity index (4.3 vs 3.6; p< 0.001) and recent hospital admission (35.3% vs 18.8%; p< 0.001) were higher among cases. By multivariable analyses, CDI risk was associated with prior hospital admission within 3 months (odds ratio [OR], 2.08; 95% CI: 1.45, 2.97), recent antibiotic use (ie, carbapenem; OR, 2.85; 95% CI: 1.75, 4.64), acid suppressive therapy use (OR, 1.71; 95% CI: 1.14, 2.58), and medical conditions (ie, renal disease; OR, 1.48; 95% CI: 1.19, 1.85). In-hospital mortality rate (18.7% vs 6.9%; p< 0.001) and mean overall LOS (33.5 vs 18.8 days; p< 0.001) were higher and longer, respectively, in cases versus controls. Conclusion: Antibiotic exposure, preexisting medical conditions, and recent hospital admission were major risk factors for CDI in Argentina, Brazil, Chile, and Mexico. CDI was associated with increased in-hospital risk of death and longer LOS. These findings are consistent with published literature in Western countries.
Descritores: Infecção Hospitalar/epidemiologia
Clostridioides difficile
Infecções por Clostridium/epidemiologia
-Argentina
Brasil/epidemiologia
Estudos de Casos e Controles
Estudos Retrospectivos
Fatores de Risco
Clostridioides
América Latina/epidemiologia
México/epidemiologia
Responsável: BR1.1 - BIREME


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Id: biblio-901210
Autor: Perovani Argüelles, Ayrelis; Vega Jiménez, Junior; Rodríguez Reyes, Sandy; Cabrera Hernández, Yailín.
Título: Caracterización clínico epidemiológica del parasitismo intestinal en pacientes jóvenes / Clinical epidemiological characterization of intestinal parasitism in young patients
Fonte: Rev. cuba. med. mil;46(2):113-123, abr.-jun. 2017. tab.
Idioma: es.
Resumo: Introducción: entre las enfermedades infecciosas, las producidas por parásitos intestinales constituyen un importante problema de salud para el hombre. Objetivo: caracterizar clínica y epidemiológicamente el parasitismo intestinal en pacientes jóvenes. Métodos: se realizó un estudio observacional, descriptivo y transversal en la consulta externa del Hospital Militar Docente Dr Mario Muñoz Monroy; el universo de estudio estuvo representado por todos los pacientes jóvenesa tendidos durante el período de noviembre de 2013 a octubre de 2014 con el diagnóstico clínico y microbiológico de parasitosis intestinal. Resultados: existió un predominio del sexo masculino con un 91 por ciento, siendo el grupo etario más afectado el de 17 a 22 años para un 60,7 por ciento. El 19,6 por ciento de los enfermos procedían del municipio Calimete. El dolor abdominal, seguido de las diarreas fueron los síntomas más referidos por los pacientes para un 96,4 por ciento y 94,6 por ciento, respectivamente. La Giardia lamblia fue el parásito más identificado en las muestras con un 51,7 por ciento, seguido del Enterobius vermicularis en un 28,6 por ciento. La mayoría de los enfermos no acostumbra a lavar los alimentos antes de su ingestión en un 83,9 por ciento de los casos estudiados, ni practican el lavado de manos previo representando el 69,6 por ciento. Conclusiones: el mayor porcentaje de pacientes enfermos procede del área rural. Los malos hábitos higiénicos-dietéticos constituyen los principales factores de riesgo(AU)

Introduction: Among the infectious diseases, those produced by intestinal parasites are a major health problem. Objective: To characterize the clinical and epidemiological aspects of intestinal parasitism in young patients. Methods: An observational, descriptive and cross-sectional study was carried out in the external consultation of the Military Teaching Hospital Dr Mario Muñoz Monroy; the universe was represented by all the young patients treated from November 2013 to October 2014 with the clinical and microbiological diagnosis of intestinal parasitosis. Results: There was a predominance of males with 91 percent, the most affected age group being 17 to 22 years old for 60.7 percent. 19.6 percent of the patients came from Calimete municipality. Abdominal pain and diarrhea were the most commonly reported symptoms for 96.4 percent and 94.6 percent, respectively. Giardia lamblia was the most identified parasite in the samples with 51.7 percent, followed by Enterobius vermicularis in 28.6 percent. The majority of patients do not usually wash their food prior to their ingestion in 83.9 percent of the cases, nor do they practice previous hand washing, representing 69.6 percent. Conclusions: The highest percentage of sick patients comes from the rural area. Bad hygienic-dietary habits are the main risk factors(AU)
Descritores: Controle de Doenças Transmissíveis/estatística & dados numéricos
Fatores de Risco
Giardia lamblia/microbiologia
Enteropatias Parasitárias/epidemiologia
-Dor Abdominal/epidemiologia
Epidemiologia Descritiva
Estudos Transversais
Estudo Observacional
Limites: Humanos
Masculino
Adulto
Adulto Jovem
Responsável: CU1.1 - Biblioteca Médica Nacional


  6 / 26998 LILACS  
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Id: biblio-901212
Autor: González Tabares, Rubén; Acosta González, Frank Abel.
Título: Utilidad de una escala de riesgo para identificar pacientes con disglucemia / Utility of a risk scale to identify patients with dysglycemia
Fonte: Rev. cuba. med. mil;46(2):135-147, abr.-jun. 2017. ilus, tab.
Idioma: es.
Resumo: Introducción: la prevalencia de diabetes y prediabetes ha ido en aumento a nivel global y en Cuba. Para identificar individuos en riesgo de disglucemia se han desarrollado varias escalas. Objetivo: evaluar el desempeño de la escala de Bang y otros, para identificar individuos con disglucemia, en una población cubana laboralmente activa. Métodos: se realizó un estudio transversal en 2 902 pacientes, fueron clasificados en portadores o no de disglucemia, a través de las pruebas de glucemia en ayunas, de tolerancia a la glucosa y hemoglobina glucosilada. Se determinó la frecuencia de factores de riesgo de diabetes mellitus tipo 2 comprendidos en la escala de Bang y otros, y en el proceder enfocado en factores de riesgo de American Diabetes Association. Se determinó sensibilidad, especificidad, valor predictivo positivo, valor predictivo negativo y Odds Ratio de ambas estrategias. En ambos se calculó el área bajo la curva operativa del receptor. Resultados: se encontró relación entre cada uno de los factores de riesgo previstos en ambos procederes con el diagnóstico de disglucemia. Se encontró sensibilidad de 96,5 por ciento y 79,9 por ciento; especificidad de 20,9 por ciento y 59,1 por ciento; valor predictivo positivo de 10,7 por ciento y 16,1 por ciento; valor predictivo negativo de 98,4 por ciento y 96,8 por ciento; OR de 7,33 y 6,76 y área bajo la curva 0,77 y 0,79 para la escala de Bang y otros, y el procedimiento enfocado en factores de riesgo, respectivamente. Conclusiones: ambos procederes identificaron de forma aceptable el grupo de pacientes con disglucemia(AU)

Introduction: The prevalence of diabetes and prediabetes has been increasing globally and also in Cuba. Several scales have been developed to identify individuals at risk for dysglycemia. Objective: To evaluate the performance of the Bang et al. scale to identify individuals with dysglycemia in a Cuban labor-active population. Methods: A cross-sectional study was carried out on 2 902 patients, classified as having or not suffering from dysglycemia, through fasting glycemia, glucose tolerance test and glycosylated hemoglobin. The frequencies of risk factors for type 2 diabetes mellitus included in the Bang et al. scale and in the risk factor approach of the American Diabetes Association were determined. Sensitivity, specificity, positive predictive value, negative predictive value and Odds Ratio of both strategies were determined. In both, the area under the receiver operating curve was calculated. Results: A relationship was found between each of the predicted risk factors in both procedures with the diagnosis of dysglycemia. Sensitivity was 96.5 percent and 79.9 percent; Specificity of 20.9 percent and 59.1 percent; Positive predictive value of 10.7 percent and 16.1 percent; Negative predictive value of 98.4 percent and 96.8 percent; OR of 7.33 and 6.76 and area under the curve 0.77 and 0.79 for the scale of Bang et al. and the procedure focused on risk factors respectively. Conclusions: Both procedures identified in an acceptable manner the group of patients with dysglycemia(AU)
Descritores: Estado Pré-Diabético/epidemiologia
Fatores de Risco
Índice Glicêmico
Diabetes Mellitus/epidemiologia
Teste de Tolerância a Glucose/métodos
-Epidemiologia Descritiva
Estudos Transversais
Valor Preditivo dos Testes
Sensibilidade e Especificidade
Limites: Humanos
Responsável: CU1.1 - Biblioteca Médica Nacional


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Id: biblio-901214
Autor: Vila García, Lázaro Osmel; Hernández Pedroso, Wilfredo; Castillo López, Beatrice; Ramos Ravelo, Deyvis; Lemes Rodríguez, Altinay; Santana Sánchez, Raúl.
Título: Caracterización de los factores modificables asociados a la letalidad hospitalaria del ictus / Characterization of the modifiable factors associated with the hospital lethality of stroke
Fonte: Rev. cuba. med. mil;46(2):163-176, abr.-jun. 2017. tab.
Idioma: es.
Resumo: Objetivos: conceptualizar el politraumatismo a la luz de los conocimientos vigentes, su génesis, la conducta a seguir durante la atención prehospitalaria y hospitalaria, la determinación de los índices de severidad relacionados con la mortalidad y sus causas, así como el tratamiento mediante equipos de trabajo multidisciplinarios especializados. Métodos: revisión documental de la bibliografía médica nacional y extranjera del presente siglo, mediante el buscador Google académico, las bases de datos Scielo, Lilacs, Pubmed, en idiomas inglés y español. Desarrollo: en la actualidad constituye un verdadero problema científico la diversidad de criterios sobre la atención de los politraumatizados en general y de los graves, en particular, porque continúan siendo un problema de salud para la población, pues suelen recibirlos fundamentalmente los varones en edades productivas de la vida, por lo general mediante accidentes y/o agresiones y requieren gran cantidad de recursos para su atención, necesitan un tratamiento precoz, intensivo y multidisciplinario, a pesar de mantener altas tasas de letalidad y mortalidad. Conclusiones: la evaluación precoz de la gravedad del trauma, permite tratar adecuadamente y con inmediatez a los lesionados y posibilita mejorar su pronóstico, debido a que se cuenta con equipos de trabajo altamente especializados, podrá elevarse la calidad asistencial y, con esa premisa, el índice de supervivencia de estos enfermos(AU)

Objectives: To conceptualize polytrauma in the light of current knowledge, its genesis, the management during prehospital and hospital care, the severity indexes related to mortality and its causes, as well as the treatment by specialized multidisciplinary teams. Methods: Documents review from national and foreign medical bibliography of this century, through the academic Google search engine, the Scielo, Lilacs, Pubmed databases, in English and Spanish. Body: At present the diversity of criteria on the care of polytraumatized in general and of the severe ones is a real scientific problem, in particular, because they continue to be a health problem for the population, since they are usually suffered by men of productive ages, usually by accidents and / or assaults and require a large amount of resources for their care, they need early, intensive and multidisciplinary treatment, despite maintaining high rates of lethality and mortality. Conclusions: the early assessment of the severity of the trauma allows the injured to be treated adequately and immediately, and it makes it possible to improve their prognosis, due to the fact that highly specialized work teams are available, the quality of care can be increased and, with that premise, the survival rate of these patients(AU)
Descritores: Fatores de Risco
Acidente Vascular Cerebral/epidemiologia
Acidente Vascular Cerebral/diagnóstico por imagem
-Estudos Prospectivos
Mortalidade Hospitalar
Acidente Vascular Cerebral/mortalidade
Estudo Observacional
Limites: Humanos
Masculino
Idoso
Responsável: CU1.1 - Biblioteca Médica Nacional


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Martins, Regina Maria Bringel
Stefani, Mariane Martins de Araujo
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Id: biblio-1249300
Autor: Pinheiro, Raquel Silva; Escola de Ciências Sociais e da SaúdeCarvalho, Paulie Marcelly Ribeiro dos Santos; Matos, Marcos André de; Caetano, Karlla Antonieta Amorim; Paula, Andressa Cunha de; Carneiro, Megmar Aparecida dos Santos; Reis, Mônica Nogueira da Guarda; Martins, Regina Maria Bringel; Stefani, Mariane Martins de Araújo; Teles, Sheila Araujo.
Título: Human immunodeficiency virus infection and syphilis among homeless people in a large city of Central-Western Brazil: prevalence, risk factors, human immunodeficiency virus-1 genetic diversity, and drug resistance mutations
Fonte: Braz. j. infect. dis;25(1):101036, jan., 2021. tab.
Idioma: en.
Projeto: Ministry of Health-STD/HIV/AIDS Coordination and Viral Hepatitis-call.
Resumo: ABSTRACT Homeless people are at high risk for sexually transmitted infections (STIs), such as human immunodeficiency virus (HIV) infection and syphilis. We investigated the epidemiology of HIV-1 infection and syphilis among homeless individuals in a large city in Central-Western Brazil. In this cross-sectional study, we interviewed and tested 355 individuals from September 2014 to August 2015. Rapid test samples positive for syphilis were retested using the Venereal Disease Research Laboratory (VDRL) test. Blood samples from HIV-infected participants were collected for POL sequencing using HIV-1 RNA extracted from plasma, reverse transcription, and nested polymerase chain reaction. Anti-HIV-1-positive samples were subtyped by sequencing the nucleotides of HIV-1 protease and part of the HIV-1 reverse transcriptase genes. Transmitted and acquired drug resistance mutations and susceptibility to antiretroviral drugs were also analyzed. Anti-HIV was positive in 14 patients (3.9%; 95% confidence interval [CI]: 2.3-6.4). HIV-1 RNA was detected in 8 of the 14 samples. Two of the eight (25%) isolates showed HIV-1 drug resistance mutations. Furthermore, 78 (22%; 95% CI: 17.9-26.5) and 29 (8.2%; 95% CI: 5.6-11.4) homeless individuals tested positive for syphilis using the rapid test and VDRL test, respectively. Two individuals were anti-HIV-1 and VDRL test positive. Daily alcohol use (adjusted odds ratio [AOR]: 3.2, 95% CI: 1.0-10.4), sex with people living with HIV (PLWH) infection (AOR: 6.8, 95% CI: 1.9-25.0), and sex with people of the same sex (AOR: 5.4, 95% CI: 1.7-17.5) were predictors of HIV infection. Age ≤35 years (AOR: 3.8, 95% CI: 1.4-10.8), previous syphilis testing (AOR: 3.5, 95% CI: 1.4-8.4), history of genital lesions (AOR: 4.9, 95% CI: 1.3-19.1), and crack use in the last six months (AOR: 3.1, 95% CI: 1.3-7.6) were predictors of syphilis. Our findings highlight the importance of STI prevention and control strategies among the homeless.
Descritores: Sífilis/epidemiologia
Infecções por HIV/epidemiologia
HIV-1/genética
-Variação Genética
Brasil/epidemiologia
Resistência a Medicamentos
Prevalência
Estudos Transversais
Fatores de Risco
Mutação
Responsável: BR1.1 - BIREME


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Id: biblio-1278575
Autor: Multiuser Laboratory for Research Support in Nephrology and Medical Sciences (LAMAP)Lino, Katia; Multiuser Laboratory for Research Support in Nephrology and Medical Sciences (LAMAP)Guimarães, Gabriel Macedo Costa; Multiuser Laboratory for Research Support in Nephrology and Medical Sciences (LAMAP)Alves, Lilian Santos; Multiuser Laboratory for Research Support in Nephrology and Medical Sciences (LAMAP)Oliveira, Any Caroline; Multiuser Laboratory for Research Support in Nephrology and Medical Sciences (LAMAP)Faustino, Renan; Multiuser Laboratory for Research Support in Nephrology and Medical Sciences (LAMAP)Fernandes, Cintia Souza; Multiuser Laboratory for Research Support in Nephrology and Medical Sciences (LAMAP)Tupinambá, Gleiser; Multiuser Laboratory for Research Support in Nephrology and Medical Sciences (LAMAP)Medeiros, Thalia; Multiuser Laboratory for Research Support in Nephrology and Medical Sciences (LAMAP)Silva, Andrea Alice da; Multiuser Laboratory for Research Support in Nephrology and Medical Sciences (LAMAP)Almeida, Jorge Reis.
Título: Serum ferritin at admission in hospitalized COVID-19 patients as a predictor of mortality
Fonte: Braz. j. infect. dis;25(2):101569, 2021. tab, graf.
Idioma: en.
Resumo: ABSTRACT Introduction: Some COVID-19 patients have higher mortality and the responsible factors for this unfavorable outcome is still not well understood. Objective: To study the association between ferritin levels at admission, representing an inflammatory state, and hospital mortality in COVID-19 patients. Methods: From May through July 2020, SARS-CoV-2 positive patients with moderate to severe clinical symptoms were evaluated at admission, regarding clinical and laboratory data on renal and hepatic function, hematologic parameters, cytomegalovirus co-infection, and acute phase proteins. Results: A total of 97 patients were included; mean age = 59.9 ± 16.3 years, 58.8% male, 57.7% non-white, in-hospital mortality = 45.4%. Age, ferritin, C-reactive protein, serum albumin and creatinine were significantly associated with mortality. Ferritin showed area under the curve (AUC) of 0.79 (p < 0.001) for the cut-off of 1873.0 ng/mL, sensitivity of 68.4% and specificity of 79.3% in predicting in-hospital mortality. Age ≥60 years had an odds ratio (OR) of 10.5 (95% CI = 1.8-59.5; p = 0.008) and ferritin ≥1873.0 ng/mL had an OR of 6.0 (95% CI = 1.4-26.2; p = 0.016), both independently associated with mortality based on logistic regression analysis. Conclusion: The magnitude of inflammation present at admission of COVID-19 patients, represented by high ferritin levels, is independently predictive of in-hospital mortality.
Descritores: COVID-19
-Estudos Retrospectivos
Fatores de Risco
Mortalidade Hospitalar
Ferritinas
SARS-CoV-2
Pessoa de Meia-Idade
Responsável: BR1.1 - BIREME


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Id: biblio-901201
Autor: de Armas Hernández, Arelys; Solís Cartas, Urbano; Prada Hernández, Dinorah Marisabel; Benítez Falero, Yosniel; Vázquez Abreu, Regla Lidia.
Título: Factores de riesgo ateroscleróticos en pacientes con artritis reumatoide / Atherosclerotic risk factors in patients with rheumatoid arthritis
Fonte: Rev. cuba. med. mil;46(1):51-63, ene.-mar. 2017. tab.
Idioma: es.
Resumo: Introducción: la artritis reumatoide es una enfermedad inflamatoria crónica y progresiva caracterizada por la inflamación de articulaciones sinoviales y manifestaciones sistémicas. Objetivo: describir las características de algunos factores de riesgo de ateroesclerosis en pacientes con artritis reumatoide. Métodos: se realizó un estudio descriptivo, de corte transversal, en 112 pacientes con diagnóstico de artritis reumatoide. Para el diagnóstico positivo se tuvieron en cuenta los criterios del American College of Rheumatology. Se aplicó un cuestionario creado para la investigación y se realizaron exámenes complementarios y determinación de medidas antropométricas para explorar la presencia de factores de riesgo de ateroesclerosis. Resultados: promedio de edad de 56,3 años, con predominio del grupo menor de 49 años, sexo femenino (81,3 por ciento); el 76,3 por ciento de los pacientes presentaron factores de riesgo aterosclerótico con predominio para el hábito de fumar (41,1 por ciento), hipertensión arterial (24,1 por ciento) y elevación del índice de masa corporal (18,8 por ciento). Conclusiones: existe alta incidencia de factores de riesgo aterosclerótico en los pacientes con artritis reumatoidea, siendo los de mayor incidencia, el hábito de fumar, la hipertensión arterial y la elevación del índice de masa corporal; el metotrexato y los esteroides, son los medicamentos que más se utilizan en el control de la artritis reumatoidea y al parecer, en las dosis usualmente utilizadas, tienen un papel protector sobre el endotelio vascular(AU)

Introduction: Rheumatoid arthritis is a chronic and progressive inflammatory disease characterized by inflammation of synovial joints and systemic manifestations. Objective: To describe some risk factors for atherosclerosis in patients with rheumatoid arthritis. Methods: A descriptive, cross-sectional study was performed in 112 patients diagnosed with rheumatoid arthritis. For the positive diagnosis the criteria of the American College of Rheumatology were taken into account. A questionnaire created for the investigation was applied and laboratory examinations and determination of anthropometric measurements were carried out to determine the presence of risk factors for atherosclerosis. Results: Mean age of 56.3 years, with predominance of age group under 49 years, female (81.3 percent); 76.3 percent of the patients had atherosclerotic risk factors with a predominance of smoking (41.1 percent), hypertension (24.1 percent) and body mass index (18.8 percent). Conclusions: There is a high incidence of atherosclerotic risk factors in rheumatoid arthritis patients, with the highest incidence of smoking, hypertension and elevation of body mass index; methotrexate and steroids are the drugs most commonly used in the control of rheumatoid arthritis and it seems that in doses usually used, they play a protective role on the vascular endothelium(AU)
Descritores: Artrite Reumatoide/diagnóstico
Metotrexato/uso terapêutico
Fatores de Risco
Aterosclerose/epidemiologia
-Epidemiologia Descritiva
Estudos Transversais
Limites: Humanos
Feminino
Pessoa de Meia-Idade
Responsável: CU1.1 - Biblioteca Médica Nacional



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