Base de dados : LILACS
Pesquisa : G05.360.340.024.380 [Categoria DeCS]
Referências encontradas : 15 [refinar]
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Id: biblio-1047452
Autor: Jiang, Liwen; Nie, Hongtao; Li, Chen; Li, Dongdong; Huo, Zhongming; Yan, Xiwu.
Título: The genetic diversity of wild and cultivated Manila clam (Ruditapes philippinarum) revealed by 29 novel microsatellite markers
Fonte: Electron. j. biotechnol;34:17-21, july. 2018. tab.
Idioma: en.
Projeto: National Natural Science Foundation of China; . Modern Agro-industry Technology Research System; . Program for Liaoning Excellent Talents in University; . Cultivation Plan for Youth Agricultural Science and Technology Innovative Talents of Liaoning Province; . Natural Science Foundation of Dalian; . Dalian Youth Science and Technology Star Project Support Program; . Scientific Research project of Liaoning Education Department.
Resumo: Background: Microsatellite loci often used as a genetic tool for estimating genetic diversity population variation in a wide variety of different species. The application of microsatellite markers in genetics and breeding includes investigating the genetic differentiation of wild and cultured populations, assessing and determining the genetic relationship of different populations. The aim of this work is to develop several microsatellite markers via highthroughput sequencing and characterize these markers in commercially important bivalve Ruditapes philippinarum. Results: Among the two populations of R. philippinarum studied, 110 alleles were detected. The number of alleles at the cultured population ranged from 3 to 17 (mean NA = 6.897) and wild population ranged from 2 to 15 (mean NA = 6.793). The observed and expected heterozygosities of cultured population ranged from 0.182 to 0.964, and from 0.286 to 0.900, with an average of 0.647 and 0.692, respectively. The observed and expected heterozygosities of wild population ranged from 0.138 to 1.000, and from 0.439 to 0.906, with an average of 0.674 and 0.693, respectively. The polymorphism information content ranged from 0.341 to 0.910 with an average of 0.687. Sixteen and thirteen microsatellite loci deviated significantly from Hardy­Weinberg equilibrium after correction for multiple tests in cultured and wild population, respectively. Conclusions: Twenty-nine novel microsatellite loci were developed using Illumina paired-end shotgun sequencing and characterized in two population of R. philippinarum.
Descritores: Variação Genética
Bivalves/genética
Repetições de Microssatélites
-Polimorfismo Genético
Aquicultura
Loci Gênicos
Genética Populacional
Limites: Animais
Responsável: CL1.1 - Biblioteca Central


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Texto completo SciELO Brasil
Texto completo
Id: biblio-828199
Autor: Barrantes, Kenia; Achí, Rosario.
Título: The importance of integrons for development and propagation of resistance in Shigella: the case of Latin America
Fonte: Braz. j. microbiol;47(4):800-806, Oct.-Dec. 2016.
Idioma: en.
Resumo: Abstract In Latin America, the disease burden of shigellosis is found to coexist with the rapid and rampant spread of resistance to commonly used antibiotics. The molecular basis of antibiotic resistance lies within genetic elements such as plasmids, transposons, integrons, genomic islands, etc., which are found in the bacterial genome. Integrons are known to acquire, exchange, and express genes within gene cassettes and it is hypothesized that they play a significant role in the transmission of multidrug resistance genes in several Gram-negative bacteria including Shigella. A few studies have described antibiotic resistance genes and integrons among multidrug resistant Shigella isolates found in Latin America. For example, in Brazil, Bolivia, Chile, Costa Rica and Peru, class 1 and class 2 integrons have been detected among multidrug resistant strains of Shigella; this phenomenon is more frequently observed in S. flexneri isolates that are resistant to trimethoprim, sulfamethoxazole, streptomycin, ampicillin, chloramphenicol, and tetracycline. The gene cassette sul2, which is frequently detected in Shigella strains resistant to the sulfonamides, suggests that the sulfonamide-resistant phenotype can be explained by the presence of the sul2 genes independent of the integron class detected. It is to be noted that sul3 was negative in all isolates analyzed in these studies.The high frequency of sulfonamide (as encoded by sul2) and trimethoprim resistance is likely to be a result of the recurrent use of trimethoprim sulfamethoxazole as a popular regimen for the treatment of shigellosis. The observed resistance profiles of Shigella strains confirm that ampicillin and trimethoprim-sulfamethoxazole are ineffective as therapeutic options. In-depth information regarding antibiotic resistance mechanism in this pathogen is needed in order to develop suitable intervention strategies. There is a pressing need for regional and local antimicrobial resistance profiling of Shigella to be included as a part of the public health strategy.
Descritores: Shigella/efeitos dos fármacos
Shigella/genética
Farmacorresistência Bacteriana
Integrons
Disenteria Bacilar/microbiologia
Disenteria Bacilar/epidemiologia
Antibacterianos/farmacologia
-Vigilância da População
Disenteria Bacilar/tratamento farmacológico
Loci Gênicos
Genes Bacterianos
América Latina/epidemiologia
Antibacterianos/uso terapêutico
Responsável: BR1.1 - BIREME


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Texto completo SciELO Saúde Pública
Texto completo
Id: lil-761811
Autor: Mas-Manchón, Lluís; Rodríguez-Bravo, Ángel; Montoya-Vilar, Norminanda; Morales-Morante, Fernando; Lopes, Elaine; Añaños, Elena; Peres, Rafaella; Martínez, María Eugenia; Grau, Antoni.
Título: Valores percibidos en la publicidad de alimentos por jóvenes con y sin trastornos de la conducta alimentaria / The perception of values in food commercials on the part of young people with and without eating disorders
Fonte: Salud colect;11(3):423-444, jul.-sep. 2015. ilus, tab.
Idioma: es.
Projeto: Ministerio de Economía y Competitividad de España.
Resumo: La publicidad utiliza imágenes corporales fuertemente estereotipadas para promocionar cánones físicos y conductas alimentarias no saludables asociadas a productos de alimentación dirigidos sobre todo a jóvenes. El objetivo de este estudio, realizado en Barcelona (España) durante el mes de mayo de 2013, es testear la percepción de 25 valores en siete spots televisivos de alimentación (con y sin estrategias de imagen corporal) en 139 jóvenes con y sin trastornos de la conducta alimentaria (TCA). Los resultados muestran que solo el grupo de jóvenes con TCA considera que los spots con una estrategia comercial basada en la imagen corporal influyen muy negativamente en valores como salud, bienestar, familia y esfuerzo. En cambio, se ha observado una gran coincidencia entre los dos grupos cuando se evalúa el resto de los spots. Estos resultados señalan que los jóvenes universitarios españoles de hoy han aceptado como normal un canon de belleza basado en el orden social y económico, mientras que los jóvenes en tratamiento por desórdenes alimenticios sí han aprendido a decodificar este tipo de mensajes.

Advertising uses stereotyped body images to promote physical ideals and unhealthy eating habits related to food products which are targeted especially at young people. The purpose of this study, carried out in Barcelona (Spain) in May 2013, was to test the perception of 139 young people of university age - with and without eating disorders - regarding 25 values in seven food commercials that did and did not use body image strategies. Results show that only the group of young people with eating disorders considered commercials using body image strategies to have a very negative influence on values such as health, well-being, family and effort. In contrast, the assessment of the two groups regarding the rest of the commercials greatly coincided. These results show that today's university youth have accepted as normal a beauty canon based on the prevailing social and economic order, while young people in treatment for eating disorders have learned to denaturalize such messages.
Descritores: Evolução Biológica
Genética Populacional
Modelos Genéticos
Seleção Genética
-Teoria do Jogo
Loci Gênicos
Genótipo
Fenótipo
Limites: Humanos
Responsável: BR1.1 - BIREME


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Texto completo SciELO Brasil
Texto completo
Id: lil-749720
Autor: Santos, Danielle Caldeira Martins dos; Costa, Thaina Miranda da; Rabello, Renata Fernandes; Alves, Fábio Aguiar; Mondino, Silvia Susana Bona de.
Título: Mannitol-negative methicillin-resistant Staphylococcus aureus from nasal swab specimens in Brazil
Fonte: Braz. j. microbiol;46(2):531-533, Apr-Jun/2015. tab.
Idioma: en.
Resumo: The isolation of mannitol-negative methicillin-resistant Staphylococcus aureus from nasal swabs is reported. Among the 59 isolates, 9 (15%) isolates were mannitol-negative; all of these isolates were categorized as staphylococcal cassette chromosome mec (SCCmec) type IVa. This report emphasizes that mannitol fermentation on mannitol salt agar should not be used as the sole criterion when screening nasal swab specimens for S. aureus.
Descritores: Manitol/metabolismo
Staphylococcus aureus Resistente à Meticilina/isolamento & purificação
Staphylococcus aureus Resistente à Meticilina/metabolismo
Mucosa Nasal/microbiologia
-Brasil
DNA Bacteriano/genética
Fermentação
Loci Gênicos
Staphylococcus aureus Resistente à Meticilina/classificação
Limites: Humanos
Responsável: BR1.1 - BIREME


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Texto completo SciELO Brasil
Texto completo
Id: lil-748310
Autor: Galego, Pedro; Silva, Fernando C.; Pinheiro, Luís Campos.
Título: Analysis of monotherapy prostate brachytherapy in patients with prostate cancer. Initial PSA and Gleason are important for recurrence?
Fonte: Int. braz. j. urol;41(2):353-359, Mar-Apr/2015. tab, graf.
Idioma: en.
Resumo: Purpose To evaluate the clinical outcome of a cohort of localized prostate cancer patients treate with 125-I permanent brachytherapy at the São José Hospital – CHLC, Lisbon. Materials and Methods A retrospective analysis was carried out on 429 patients with low and intermediate-risk of prostate adenocarcinoma, according to the recommendations of the EORTC, who underwent 125I brachytherapies in intraoperative dosimetry “real-time” system between September 2003 and September 2013. Results The mean follow-up was 71.98 months. Biochemical relapse of disease by rising PSA (Phoenix criterion) was observed in 18 patients (4.2%). Through the application of Kaplan-Meier survival curves in this sample, the rate of survival at 6 years without biochemical relapse was higher than 95%. By Iog rank test comparing biochemical relapse with initial PSA (15-10 and <10) and Gleason values (7 and <7), there was no statistical difference (P=0.830) of the initial PSA in the probability of developing biochemical relapse. In relation to Gleason score, it was noted a statistical difference (P<0.05), demonstrating that patients with Gleason 7 are more likely to develop biochemical relapse. Conclusions Brachytherapy as monotherapy is at present an effective choice in the treatment of localized prostate adenocarcinoma. Biochemical relapses are minimal. The initial PSA showed no statistically difference in the rate of relapses, unlike the value Gleason, where it was demonstrated that patients with Gleason 7 have a higher probability of biochemical relapse. Cases with PSA bounce should be controlled before starting a salvage treatment. .
Descritores: Genoma Humano
Estudo de Associação Genômica Ampla
Loci Gênicos/genética
Pneumopatias/genética
Capacidade Vital/genética
-Estudos de Coortes
Bases de Dados Genéticas
Seguimentos
Volume Expiratório Forçado
Predisposição Genética para Doença
Pneumopatias/patologia
Metanálise como Assunto
Prognóstico
Polimorfismo de Nucleotídeo Único/genética
Locos de Características Quantitativas/genética
Testes de Função Respiratória
Espirometria
Limites: Humanos
Responsável: BR1.1 - BIREME


  6 / 15 LILACS  
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Texto completo SciELO Saúde Pública
Pordeus, Isabela Almeida
Texto completo
Id: lil-744894
Autor: Martins, Andréa Maria Eleutério de Barros Lima; Souza, João Gabriel Silva; Haikal, Desireé Sant'Ana; Paula, Alfredo Maurício Batista de; Ferreira, Efigênia Ferreira e; Pordeus, Isabela Almeida.
Título: Prevalence of oral cancer self-examination among elderly people treated under Brazil's Unified Health System: household health survey / Prevalência de autoexame bucal é maior entre idosos assistidos no Sistema Único de Saúde: inquérito domiciliar
Fonte: Ciênc. saúde coletiva;20(4):1085-1098, 04/2015. tab, graf.
Idioma: en.
Resumo: The aim of this study was to examine the prevalence of oral cancer self-examinationamong the elderly and confirm whether prevalence was higher among users of the dental services provided by Brazil's Unified Health System (SUS, acronym in Portuguese). A transversal study of elderly people aged between 65 and 74 years living in a large-sized Brazilian municipality was conducted using simple random sampling. Logistic regression was conducted and results were corrected for sample design and unequal weighting using the SPSS(r) software. The study assessed 740 individuals. A total of 492 met the inclusion criteria, of which 101 (22.4%) reported having performed an oral cancer self-examination. Prevalence was higher among users of the dental services provided by the SUS, higher-income individuals, people with higher levels of education, individuals that used a removable dental prosthesis, and people who had not experienced discomfort attributed to oral condition, and lower among people who sought regular and periodic dental treatment and individuals who did not have a drinking habit. This type of self-care should be encouraged by public health policies which respond to the needs of the elderly, with emphasis on users of private and philanthropic services, and other services outside the public health network.

Este estudo objetivou identificar a prevalência do autoexame bucal entre idosos e constatar se essa prevalência foi maior entre usuários de serviços odontológicos prestados pelo Sistema Único de Saúde (SUS). Estudo transversal conduzido a partir de amostragem probabilística complexa por conglomerados, entre idosos (65-74 anos) de um município brasileiro de grande porte populacional. Foi realizada regressão logística binária, as estimativas foram corrigidas pelo efeito de desenho e por ponderações, utilizando-se o SPSS(r). Dentre os 740 avaliados, atenderam aos critérios de inclusão 492 idosos e, destes, 101 (22,4%) relataram a prática do autoexame bucal. Esta prática foi maior entre idosos usuários dos serviços odontológicos prestados no SUS, entre aqueles com maior renda per capita, os com maior escolaridade, aqueles que utilizavam prótese dentária removível e entre os que não tiveram impactos decorrentes das desordens bucais; foi menor entre os que usaram serviços odontológicos por rotina e os que não possuíam hábito etilista. A prevalência do autoexame bucal entre idosos foi baixa e maior entre aqueles usuários do SUS. O estímulo à adesão a este autocuidado deve ser considerado nas políticas de saúde do idoso vigentes, especialmente entre usuários de serviços particulares, supletivos e filantrópicos.
Descritores: /genética
CHROMOSOMES, HUMAN, PAIR ABDOMEN, ACUTE/genética
Dislexia/genética
Transtornos da Linguagem/genética
-Colorado
Loci Gênicos
Genótipo
Haplótipos
Testes de Inteligência
Iowa
Itália
Desequilíbrio de Ligação
Estudos Longitudinais
Proteínas Associadas aos Microtúbulos/genética
Proteínas do Tecido Nervoso/genética
Proteínas Nucleares/genética
Fenótipo
Pseudogenes
Testes Psicológicos
Proteínas/genética
Leitura
Tioléster Hidrolases/genética
Fatores de Transcrição/genética
Limites: Criança
Humanos
Tipo de Publ: Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Responsável: BR1.1 - BIREME


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Texto completo SciELO Saúde Pública
Assunçäo, Ada Avila
Barreto, Sandhi Maria
Texto completo
Id: lil-744852
Autor: Lima, Eduardo de Paula; Assunção, Ada Ávila; Barreto, Sandhi Maria.
Título: Prevalência de depressão em bombeiros / Prevalence of depression among firefighters / Prevalencia de depresión en bomberos
Fonte: Cad. saúde pública = Rep. public health;31(4):733-743, 04/2015. tab.
Idioma: pt.
Resumo: A depressão apresenta alta carga de doença no mundo. Fatores socioeconômicos e exposição a situações extremas no trabalho podem estar associados à doença. O objetivo do trabalho é investigar a prevalência e fatores associados à depressão em bombeiros de Belo Horizonte, Minas Gerais, Brasil. Estudo transversal foi realizado em universo de bombeiros do sexo masculino em Belo Horizonte (n = 711). O Inventário Beck para Depressão (IBD) foi utilizado para avaliar a presença de depressão. Modelos de regressão logística (uni e multivariada) foram utilizados para estudar a associação entre características sociodemográficas, estressores ocupacionais, situação de saúde e depressão. A prevalência de depressão na amostra estudada foi 5,5%. A chance de depressão foi maior entre bombeiros que relataram sintomas de estresse pós-traumático (OR = 12,47; IC95%: 5,64-27,57) e uso abusivo de álcool (OR = 5,30; IC95%: 2,35-11,96). Os resultados são discutidos considerando as inter-relações entre transtornos mentais, o efeito do trabalhador sadio e o reconhecimento social do trabalho dos bombeiros.

Depression burder is high worldwide. Socioeconomic factors and exposure to extreme situations at work may be associated with the illness. This study focused on the prevalence of depression and associated factors among firefighters in Belo Horizonte, Minas Gerais State, Brazil. A cross-sectional study was conducted among male firefighters in Belo Horizonte (n = 711). The Beck Depression Inventory (BDI) was used to assess depression. Univariate and multivariate logistic regression models were used to study the association between socio-demographic characteristics, occupational stressors, health status, and depression. Prevalence of depression in the sample was 5.5%. The likelihood of developing depression was higher among firefighters who reported post-traumatic stress symptoms (OR = 12.47; 95%CI: 5.64-27.57) and alcohol abuse (OR = 5.30; 95%CI: 2.35-11.96). The results are discussed considering the interrelationships between mental disorders, the healthy worker effect, and social recognition of firefighters' work.

La depresión tiene una alta carga como enfermedad mundial. Factores socioeconómicos y la exposición a situaciones extremas en el trabajo pueden estar asociados con la enfermedad. El objetivo de este trabajo es investigar la prevalencia y los factores asociados con la depresión en los bomberos de Belo Horizonte, Minas Gerais, Brasil. Se trata de un estudio transversal, realizado entre los bomberos de sexo masculino de Belo Horizonte (n = 711). Se utilizó el Inventario de Depresión de Beck (IDB) para evaluar la presencia de depresión. Se utilizaron modelos de regresión logística para estudiar la asociación entre características sociodemográficas, estrés ocupacional, estado de salud y depresión. La prevalencia de depresión fue de un 5,5%. La posibilidad de depresión fue mayor entre los bomberos que informaron síntomas de estrés postraumático (OR = 12,47; IC95%: 5,64-27,57) y abuso de alcohol (OR = 5,30, IC95%: 2,35-11,96). Los resultados son discutidos considerando las interrelaciones entre los trastornos mentales, el efecto en trabajadores sanos y el reconocimiento social de la labor de bomberos.
Descritores: /genética
DIABETES MELLITUS, TYPE TEMEFOS/genética
Estudo de Associação Genômica Ampla
Inibidores de Dissociação do Nucleotídeo Guanina/genética
Transportadores de Ácidos Monocarboxílicos/genética
-Loci Gênicos
Predisposição Genética para Doença
Variação Genética
Genoma Humano
Haplótipos
Leptina/genética
MicroRNAs/genética
Polimorfismo de Nucleotídeo Único
Limites: Humanos
Tipo de Publ: Research Support, Non-U.S. Gov't
Responsável: BR1.1 - BIREME


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Texto completo SciELO Chile
Texto completo
Id: lil-742555
Autor: Ansoleaga, Elisa; Garrido, Pablo; Domínguez, Constanza; Castillo, Soledad; Lucero, Claudia; Tomicic, Alemka; Martínez, Claudio.
Título: Facilitadores del reintegro laboral en trabajadores con patología mental de origen laboral: una revisión sistemática / Return to work enablers for workers with work-related mental illness
Fonte: Rev. méd. Chile;143(1):85-95, ene. 2015. ilus, tab.
Idioma: es.
Projeto: Universidad Diego Portales. Clínica Psicológica y el Programa de Estudios Psicosociales del Trabajo; . Milenio de Investigación en Depresión (Iniciativa Científica Milenio del Ministerio de Economía, Fomento y Turismo; . Asociación Chilena de Seguridad. Coordinación Nacional de Salud Mental; . Asociación Chilena de Seguridad. Fundación Científica y Tecnológica.
Resumo: Background: There is growing interest in the treatment and return-to-work of workers with labor related mental illnesses. Aim: To perform a systematic review of practices and interventions that improve return to work. Material and Methods: Systematic literature review. Thirty articles were selected for in- depth analysis. Results: Self efficacy perception, work motivation, a lower age and a better socioeconomic status were identified as worker-related return to work facilitators. Among work environment facilitators, good communication practices, supervisor support, a good assessment and modification of work load, adjustment of expectations, a good relationship between employers and employees and positive work experiences were identified. Treatment may improve return to work using a multidisciplinary approach, reducing stress and identifying psychosocial determinants of mental problems rather than symptoms and providing a timely health care. Conclusions: Return to work of workers with labor related mental illnesses requires a constant sharing of information between health care workers, employers and employees to identify common therapeutic objectives.
Descritores: CHROMOSOMES, HUMAN, PAIR ABDOMEN, ACUTE
Grupo com Ancestrais do Continente Europeu/genética
Loci Gênicos
Lipoproteína(a)/sangue
Lipoproteína(a)/genética
Polimorfismo de Nucleotídeo Único
-Estudos de Coortes
Europa (Continente)
Estudos de Associação Genética
Genótipo
Análise de Sequência com Séries de Oligonucleotídeos
Fenótipo
Limites: Adulto
Idoso
Feminino
Humanos
Masculino
Pessoa de Meia-Idade
Tipo de Publ: Metanálise
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.
Responsável: CL1.1 - Biblioteca Central


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Texto completo SciELO Brasil
Texto completo
Id: lil-735786
Autor: Tavares, R. A; Piedras, S. R. N; Nunes, M. D; Almeida, D. B; Moreira, C. G. A; Fernandes, J. M; Freitas, S. F; Moreira, H. L. M; Pouey, J. L. O. F; Dionello, N. J. L.
Título: Identificação de loci microssatélites com potencial de amplificação na espécie de Peixe-Rei (Odontesthes humensis) / Identification of microsatellite loci with amplification potential in "pejerrey" (Odontesthes humensis)
Fonte: Arq. bras. med. vet. zootec;66(6):1941-1945, 12/2014. graf.
Idioma: pt.
Resumo: In this work, 25,806 potentially amplifiable microsatellite loci (PAL) were identified in pejerrey, (Odontesthes humensis), with 21% of dinucleotide, 22% trinucleotide, 37% tetranucleotide, 13% pentanucleotide and 7% hexanucleotide. Of the total loci, 167 were classified as "Best PAL", more likely to be variables in populations. The results show that with a small coverage of the genome it was possible to identify a large number of microsatellite loci...
Descritores: Genoma/genética
Loci Gênicos/genética
Peixes/genética
-Aquicultura
Melhoramento Genético
Repetições de Microssatélites/genética
Limites: Animais
Responsável: BR68.1 - Biblioteca Virginie Buff D'Ápice


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Texto completo SciELO Brasil
Texto completo
Id: lil-719310
Autor: Tian, Y.G.; Yue, M.; Gu, Y.; Gu, W.W.; Wang, Y.J..
Título: Single-nucleotide polymorphism analysis of GH, GHR, and IGF-1 genes in minipigs
Fonte: Braz. j. med. biol. res = Rev. bras. pesqui. méd. biol;47(9):753-758, 09/2014. tab.
Idioma: en.
Projeto: This research was supported by the Guangdong Natural Science Foundation; . ; China Postdoctoral Science Foundation; . ; the National High Technology Research and Development Program of China (863 Program: #2011AA100304); Science and Technology Planning Project; . of Guangzhou City, Guangdong Province, China; Conditions for scientific research project; . of Guangdong Province, China; Key Program for International S&T Cooperation Projects of China; . ; Torch Program; . , and Development Foundation of Special High-tech Zone.
Resumo: Tibetan (TB) and Bama (BM) miniature pigs are two popular pig breeds that are used as experimental animals in China due to their small body size. Here, we analyzed single-nucleotide polymorphisms (SNPs) in gene fragments that are closely related to growth traits [growth hormone (GH), growth hormone receptor (GHR), and insulin-like growth factor (IGF)-1)] in these pig breeds and a large white (LW) control pig breed. On the basis of the analysis of 100 BMs, 108 TBs, and 50 LWs, the polymorphic distribution levels of GH, GHR, and IGF-1 were significantly different among these three pig breeds. According to correlation analyses between SNPs and five growth traits - body weight (BW), body length (BL), withers height (WH), chest circumference (CC), and abdomen circumference (AC) - three SNP loci in BMs and four SNP loci in TBs significantly affected growth traits. Three SNP sites in BMs and four SNP sites in TBs significantly affected growth traits. SNPs located in the GH gene fragment significantly affected BL and CC at locus 12 and BL at locus 45 in BMs, and also BW, WH, CC, and AC at locus 45 and WH and CC at locus 93 in TBs. One SNP at locus 85 in the BM GHR gene fragment significantly affected all growth traits. All indices were significantly reduced with a mixture of alleles at locus 85. These results provide more information regarding the genetic background of these minipig species and indicate useful selection markers for pig breeding programs.
Descritores: Hormônio do Crescimento/genética
Fator de Crescimento Insulin-Like I/genética
Polimorfismo de Nucleotídeo Único/fisiologia
Receptores da Somatotropina/genética
Porco Miniatura/genética
-Alelos
Tamanho Corporal
DNA
Nanismo/genética
Loci Gênicos
Genótipo
Reação em Cadeia da Polimerase
Análise de Sequência de DNA
Suínos
Limites: Animais
Tipo de Publ: Research Support, Non-U.S. Gov't
Responsável: BR1.1 - BIREME



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BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde