Base de dados : LILACS
Pesquisa : G09.772.705.349 [Categoria DeCS]
Referências encontradas : 1 [refinar]
Mostrando: 1 .. 1   no formato [Detalhado]

página 1 de 1

  1 / 1 LILACS  
             
seleciona
para imprimir
Fotocópia
Texto completo SciELO Brasil
Texto completo
Id: lil-797886
Autor: Herrera Campos, CR; Beltramini, GC; Avelar, WM; Lima, FO; Li, LM.
Título: Cerebral vasomotor reactivity assessment using Transcranial Doppler and MRI with apnea test
Fonte: Braz. j. med. biol. res = Rev. bras. pesqui. méd. biol;49(11):e5437, 2016. tab, graf.
Idioma: en.
Projeto: FAPESP; . CNPq.
Resumo: Differently from previous studies that used Transcranial Doppler (TCD) and functional MRI (fMRI) for cerebral vasomotor reactivity (CVR) assessment in patients with carotid stenosis (CS), we assessed CVR using an identical stimulus, the Breath-Holding Test (BHT). We included 15 patients with CS and 7 age-matched controls to verify whether fMRI responded differently to BHT between groups and to calculate the agreement rate between tests. For TCD, impaired CVR was defined when the mean percentage increase on middle cerebral artery velocities was ≤31% on 3 consecutive 30-s apnea intercalated by 4-min normal breathing intervals. For fMRI, the percent variation on blood oxygen level-dependent (BOLD) signal intensity in the lentiform nucleus (LN) ipsilateral to the CS (or both LNs for controls) from baseline breathing to apnea was measured. The Euclidian differences between the series of each subject and the series of controls and patients classified it into normal or impaired CVR. We found different percent variations on BOLD-signal intensities between groups (P=0.032). The agreement was good in Controls (85.7%; κ=0.69) and overall (77.3%; κ=0.54). We conclude that BHT was feasible for CVR assessment on fMRI and elicited different BOLD responses in patients and controls, with a good overall agreement between the tests.
Descritores: Suspensão da Respiração
Estenose das Carótidas/diagnóstico por imagem
Circulação Cerebrovascular/fisiologia
Oxigênio/sangue
Sistema Vasomotor/diagnóstico por imagem
-Velocidade do Fluxo Sanguíneo
Estenose das Carótidas/fisiopatologia
Estudos de Casos e Controles
Imagem por Ressonância Magnética
Ultrassonografia Doppler Transcraniana
Sistema Vasomotor/fisiopatologia
Limites: Seres Humanos
Masculino
Feminino
Meia-Idade
Idoso
Idoso de 80 Anos ou mais
Tipo de Publ: Estudo Comparativo
Responsável: BR1.1 - BIREME



página 1 de 1
   


Refinar a pesquisa
  Base de dados : Formulário avançado   

    Pesquisar no campo  
1  
2
3
 
           



Search engine: iAH v2.6 powered by WWWISIS

BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde