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Id: biblio-1013729
Autor: Malavolta, Eduardo Angeli; Gracitelli, Mauro Emilio Conforto; Assunção, Jorge Henrique; Ferreira Neto, Arnaldo Amado.
Título: Answer to letter to the editor regarding the article "Asian ethnicity: a risk factor for adhesive capsulitis?" / Carta resposta referente ao artigo "Etnia Asiática: um fator de risco para a capsulite adesiva?"
Fonte: Rev. bras. ortop;54(3):358-359, May-June 2019.
Idioma: en.
Descritores: Bursite
Grupo com Ancestrais do Continente Asiático
Tipo de Publ: Carta
Responsável: BR26.1 - Biblioteca Central


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Id: biblio-1013733
Autor: Bastos, Robson Massi; Campos, Shirley Ferreira; Prianti, Bruno de Moraes.
Título: Letter to the Editor Regarding the Article "Asian ethnicity: a risk factor for adhesive capsulitis?" / Carta ao editor sobre o artigo: Etnia asiática: um fator de risco para a capsulite adesiva?
Fonte: Rev. bras. ortop;54(3):357-357, May-June 2019.
Idioma: en.
Descritores: Bursite
Grupo com Ancestrais do Continente Asiático/genética
Tipo de Publ: Carta
Responsável: BR26.1 - Biblioteca Central


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Id: biblio-1002273
Autor: Zhang, Zhifeng; Zhang, Qida; Zhao, Guanghui; Huang, Jian; Chen, Zhenxian; Jin, Zhongmin; Qiu, Yusheng.
Título: Morphological measurements of the normal distal femur and proximal tibia between han Chinese and Mongolian Chinese in a healthy Chinese population / Mediciones morfológicas del fémur distal normal y la tibia proximal entre chinos han y mongoles en una población china sana
Fonte: Int. j. morphol;37(2):664-670, June 2019. tab, graf.
Idioma: en.
Resumo: This study aims to compare the knee morphological difference between Han and Mongolian Chinese in China. This will improve the knee prostheses design. A total of 37 natural knees of Han Chinese (13 males, 9 females) and Mongolian Chinese (8 males, 7 females) were measured used Mimics medical imaging program, and the parameters included fML (the femoral mediolateral length), fLAP (the femoral lateral condyle anteroposterior length), fMAP (the femoral medial condyle anteroposteriorlength), tML (The tibial mediolateral length ) , tLAP (The tibial lateral anteroposteriorlength) and tMAP (the tibial medial anteroposterior length), The aspect ratio (defined as fML/fAP and tML/tAP;). The sizes of femur and tibia of the males were larger than those of the female for Han Chinese (fML, fLAP and fMAP) mean ± standard deviation: 84.57 ± 4.70 vs.76.52 ± 3.56, 65.75 ± 2.70 vs. 60.53 ± 3.81 and 67.10 ± 3.67vs. 62.1 2± 3.55; tML, tLAP and tMAP: 74.68 ± 4.27 vs. 65.82 ± 3.51 , 36.13 ± 2.96 vs. 31.12 ± 2.91 and 44.54 ± 3.02 vs. 40.11 ± 3.80 and Mongolian Chinese (fML, fLAP and fMAP) : 88.20 ± 4.57 vs. 77.92 ± 2.97, 68.82 ± 4.22 vs. 61.31 ± 1.92 and 69.81 ± 3.53 vs. 62.13 ± 1.63; tML, tLAP and tMAP: 78.00 ± 3.80 vs. 66.71 ± 3.52, 40.17 ± 3.09 vs. 32.91 ± 1.68 and 48.65 ± 3.00 vs. 41.97 ± 2.48). The aspect ratio of the knee in Mongolian Chinese was smaller than those of Han Chinese (fML/fAP:1.28±0.04 vs.1.29±0.03 for males;1.27±0.04 vs.1.27±0.05; tML/tAP: 1.60±0.04 vs. 1.68±0.10 for the males, 1.59±0.13 vs. 1.65±0.10 for the females). The effects of nationality and sex on the size and shape of knee were significant (p<0.05). The results suggest that an anatomic matched knee prosthesis should be taken into account different nationalities even in the same race.

Este estudio tiene como objetivo comparar la diferencia morfológica de rodilla entre los chinos Han y los Mongoles en China. Esto mejorará el diseño de las prótesis de rodilla. Un total de 37 rodillas de chinos Han (13 hombres, 9 mujeres) y Mongoles (8 hombres 7 mujeres) se midieron utilizando el programa de imágenes médicas Mimics, y los parámetros incluyeron fML (la longitud mediolateral femoral), fLAP (la longitud anteroposterior del cóndilo lateral del fémur), fMAP (la longitud anteroposterior del cóndilo medial del fémur), tML (la longitud mediolateral de la tibia), tLAP (la longitud anteroposterior lateral de la tibia) y tMAP (la longitud anteroposterior media de la tibia), la relación de aspecto (definida como fML / fAP y tML / tAP;). Los tamaños de fémur y tibia de los hombres fueron mayores que los de las mujeres para los chinos Han (fML, fLAP y fMAP) [media ± desviación estándar: 84,57±4,70 vs. 76,52±3,56, 65,75±2,70 vs. 60,53±3,81 y 67,10±3,67 vs. 62,12±3,55; tML, tLAP y tMAP: 74,68±4,27 vs. 65,82±3,51, 36,13±2,96 vs. 31,12±2,91 y 44,54±3,02 vs. 40,11±3,80 y Chino Mongol (fML, fLAP y fMAP): 88,20±4,57 vs. 77,92±2,97, 68,82±4,22 vs. 61,31±1,92 y 69,81±3,53 vs. 62,13±1,63; tML, tLAP y tMAP: 78,00±3,80 vs. 6671±3,52, 40,17±3,09 vs. 32,91±1,68 y 48,65±3,00 vs. 41,97±2,48]. La relación de aspecto de la rodilla del Chino Mongol fue menor que la de los chinos Han (fML / fAP: 1,28±0,04 vs.1,29±0,03 para los hombres; 1,27±0,04 vs. 1,27±0,05; tML / tAP: 1,60±0,04 vs. 1,68±0,10 para los hombres, 1,59±0,13 vs. 1,65±0,10 para las mujeres). Los efectos de la nacionalidad y el sexo en el tamaño y la forma de la rodilla fueron significativos (p <0,05). Los resultados sugieren que una prótesis anatómica de rodilla emparejada debe tenerse en cuenta en las diferentes nacionalidades, incluso en la misma raza.
Descritores: Grupo com Ancestrais do Continente Asiático
Joelho/anatomia & histologia
-Tíbia/anatomia & histologia
Grupos Étnicos
China
Fêmur/anatomia & histologia
Limites: Seres Humanos
Masculino
Feminino
Adulto
Meia-Idade
Responsável: CL1.1 - Biblioteca Central


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Id: biblio-994750
Autor: Holipah, ?; Hinoura, Takuji; Kozaka, Naomi; Kuroda, Yoshiki.
Título: The correlation between PER3 rs2640908 polymorphism and colorectal Cancer in the Japanese population
Fonte: Appl. cancer res;39:1-6, 2019. tab.
Idioma: en.
Resumo: Background: Colorectal cancer (CRC) is one of the most common cancers in Japan. Many factors influence this cancer, one of which is circadian rhythm disruption. Our research investigated the correlation between singlenucleotide polymorphisms (SNPs) in the Period 3 (PER3) (rs2640908), which is one of the circadian genes, and colorectal cancer in the Japanese population. Methods: The study participants consisted of 121 cases and 197 controls. DNA was extracted from participants' peripheral blood cells, and polymerase chain reaction­restriction fragment length polymorphism analysis (PCRRFLP) was performed to detect genotypes of PER3. Results: Participants with T/T genotype were at lower risk of developing colorectal cancer than participants with C/C genotype (adjusted ORs = 0.32 (95% CI: 0.15­0.63)). When stratified by gender and smoking status, T/T genotype were associated with a decreased susceptibility to cancer in males only (adjusted ORs: 0.23 (95% CI: 0.09­0.59)), T/T genotype were also associated with a decreased susceptibility to cancer among both smokers and non-smokers. Conclusions: A significant association was found between the T allele of PER3 polymorphism and a reduced risk of colorectal cancer, especially in males. Smoking status showed no association with the relationship between PER3 genotype and CRC carcinogenesis (AU)
Descritores: Polimorfismo Genético
Neoplasias Colorretais
Fatores de Risco
Grupo com Ancestrais do Continente Asiático
Genótipo
Limites: Seres Humanos
Masculino
Feminino
Responsável: BR30.1 - Biblioteca


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Id: lil-708747
Autor: Dong, Qiang; Tian, Wei; Ma, Baotong.
Título: Evaluation and clinical application of sacral s1 vestibule measurements in chinese adults / Evaluación y aplicación clínica de las mediciones del vestíbulo sacral s1 en adultos chinos
Fonte: Int. j. morphol;32(1):202-207, Mar. 2014. ilus, tab.
Idioma: en.
Resumo: This study aims to measure the anatomic parameters of the sacral 1 (S1) vestibule in Chinese adults and to discuss their clinical application during iliosacral screw fixation for pelvic posterior ring injury. Three-dimensional computed tomography (CT) reconstructions were performed on 36 individuals, and the parameters of their S1 vestibules were measured. Vestibular width (VW) was 25.15±2.91 mm, vestibular height (VH) was 20.94±3.03 mm, and mean vestibular size (VS) was 400.23±85.11 mm2. The mean angle of superior inclination was 30.85°±9.22°, and the mean anterior inclination (AI) was 13.91°±6.25°. VW and VS were significantly smaller in females than in males (p<0.05), but no statistical differences were found between the left and right sides. The S1 vestibules of Chinese patients are smaller than those reported for Caucasians. Therefore, the placement of iliosacral screws should be considered carefully based on the size, gender, and ethnicity of the patient. The anatomic parameters of females were much smaller than those of males and close to the minimum requirement for fracture fixation. Therefore, female Chinese patients who need iliosacral screws should undergo preoperative CT scans to measure S1 vestibule parameters to make individual operational plans.

El estudio tuvo como objetivo medir los parámetros anatómicos del vestíbulo sacral 1 (S1) en individuos adultos chinos y discutir su aplicación clínica durante la fijación de tornillo iliosacral por lesiones del anillo pélvico posterior. Se realizaron reconstrucciones de tomografía computarizada tridimensional (TC) en 36 individuos y se midieron los parámetros de sus vestíbulos S1. El ancho vestibular (AV) fue 25,15±2,91 mm, la altura vestibular fue 20,94±3,03 mm y el tamaño medio vestibular (TV) fue 400,23±85,11 mm2. El ángulo medio de inclinación superior fue 30,85°±9,22° e inclinación anterior media fue 13,91°±6,25°. AV y TV fueron significativamente menores en las mujeres que en los hombres (p<0,05), sin embargo no se encontraron diferencias estadísticas entre los lados izquierdo y derecho. Los vestíbulos S1 de pacientes chinos son más pequeños que los reportados para los caucásicos. Por lo tanto, la colocación de tornillos iliosacros debe ser considerada cuidadosamente basada en el tamaño, el sexo y origen étnico del paciente. Los parámetros anatómicos de las mujeres eran significativamente más pequeños que los de los hombres y cercanos al requerimiento mínimo para la fijación de fracturas. Por lo tanto, pacientes de sexo femenino chino que requieren tornillos iliosacros deben ser sometidos a tomografías computarizadas preoperatorias para medir los parámetros del vestíbulo S1 a con el objetivo de programar un plan operativo individual.
Descritores: Articulação Sacroilíaca
Articulação Sacroilíaca/anatomia & histologia
-Sacro
Sacro/anatomia & histologia
Parafusos Ósseos
Tomografia Computadorizada por Raios X
Grupo com Ancestrais do Continente Asiático
Responsável: CL1.1 - Biblioteca Central


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Id: lil-753878
Autor: Santos, Caynnã de Camargo; Acevedo, Claudia Rosa.
Título: A minoria modelo: uma análise das representações de indivíduos orientais em propagandas no Brasil / The model minority: an analysis of the portrayals of asians in advertisements in Brazil / La minoría modelo: una análisis de las representaciones de los asiáticos en anuncios en Brasil / La minorité nodèle: une analyse de la représentation des personnes d'origine orientale dans la publicité au Brésil
Fonte: Rev. psicol. polit;13(27):281-300, ago. 2013. tab.
Idioma: pt.
Resumo: O objetivo do presente estudo é analisar de que forma orientais são representados em peças publicitárias em revistas no Brasil, avaliando se tais retratos reforçam ou negam o curioso estereótipo de "Model Minority" atribuído ao grupo, apontado em pesquisas anteriores (Cohen, 1992; Delener & Neelankavil, 1990). Este estereótipo afirma que a comunidade oriental é especialmente séria, detentora de conhecimentos acima da média nos campos da matemática e tecnologia e, em geral, intelectualmente talentosa. Através da metodologia de pesquisa quantitativa denominada "análise de conteúdo", foram analisadas 200 propagandas veiculadas em quatro publicações brasileiras de temática distinta. Os resultados do estudo revelam que orientais são consistentemente retratados em certos tipos de categorias de produtos, revistas, situações e relacionamentos de forma a reforçar os estereótipos atribuídos à minoria.

The aim of this study is to examine how Asians are represented in advertisements in magazines in Brazil, assessing whether such portrayals reinforce or deny the curious stereotype of "Model Minority" (Cohen, 1992; Delener & Neelankavil, 1990). This stereotype suggests that the Asian community is specially serious, bearer of knowledge in the fields of mathematics and technology and, in general, intellectually talented. Through the quantitative research methodology called "content analysis", it was analyzed 200 advertisements conveyed in four Brazilian publications of different themes. The findings indicate that Asians are consistently portrayed in certain types of product categories, magazines, situations and relationships in order to reinforce the social stereotype attributed to the minority.

El objetivo del estudio consistió en examinar la manera en que los asiáticos son representados en la publicidad en revistas en Brasil, para evaluar si tales representaciones reforzan o rechazan el curioso estereotipo de "Minoría Modelo" (Cohen, 1992; Delener & Neelankavil, 1990). Este estereotipo afirma que la comunidad asiática es especialmente seria, portadora de conocimientos en los campos de las matemáticas y la tecnología y, en general, intelectualmente talentosa. A través de la metodología de investigación cuantitativa llamada "análisis de contenido", se analizó 200 anuncios de cuatro publicaciones brasileñas de temáticas distintas. Los resultados del estudio muestran que los asiáticos son constantemente retratados en ciertos tipos de categorías de productos, revistas, situaciones y relaciones de manera a reforzar el estereotipo social atribuido a la minoría.

Cette étude a pour but d'analyser la manière dont les Orientaux sont représentés dans des annonces publicitaires publiées dans des magazines brésiliens, de façon à évaluer si ces portraits renforcent ou renient le curieux stéréotype de « Model Minority ¼ attribué au groupe et signalé dans des recherches antérieures (Cohen, 1992 ; Delener et Neelankavil, 1990). Ce stéréotype affirme que la communauté orientale est particulièrement sérieuse, qu'elle détient des savoirs au-dessus de la moyenne dans les domaines des mathématiques et de la technologie, et qu'elle est d'une manière générale talentueuse du point de vue intellectuel. À travers la méthodologie de recherche quantitative intitulée « analyse de contenu ¼, 200 annonces diffusées dans quatre publications brésiliennes à des thématiques distinctes ont été analysées. Les résultats de cette étude révèlent que les Orientaux sont souvent représentés par certaines catégories de produits, de magazines, de situations et de relations de manière à renforcer les stéréotypes attribués à la minorité.
Descritores: Propaganda
Estereotipagem
Grupo com Ancestrais do Continente Asiático
Responsável: BR85.1 - Biblioteca Dante Moreira Leite


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Id: biblio-889120
Autor: Sun, Qing-Qing; Hua, Dong-Jin; Huang, Si-Chao; Cen, Han; Zhou, Li; Shao, Song.
Título: Association study of AFF1 rs340630 polymorphism with genetic susceptibility to rheumatoid arthritis in Chinese population
Fonte: Braz. j. med. biol. res = Rev. bras. pesqui. méd. biol;51(7):e7126, 2018. tab.
Idioma: en.
Projeto: National Natural Science Foundation; . Nature Science Foundation; . Ningbo University Talent Project.
Resumo: This study was performed to examine whether the AF4/FMR2 family, member 1 (AFF1) rs340630 polymorphism is involved in the genetic background of rheumatoid arthritis (RA) in a Chinese population. Two different study groups of RA patients and controls (328 RA patients and 449 healthy controls in the first study group; 232 RA patients and 313 controls in the second study group) were included in our study. Overall, there was no significant difference in either genotype (P=0.71 and 0.64 in the first and second study group, respectively) nor allele (in the first study group: A vs G, P=0.65, OR=1.05, 95%CI=0.85-1.29; in the second study group: G vs A, P=0.47, OR=1.10, 95%CI=0.86-1.40) frequencies of AFF1 rs340630 polymorphism between RA patients and controls. Our study represents the first report assessing the association of AFF1 rs340630 polymorphism with RA risk. No significant evidence was found for the dominant or recessive models. Further case-control studies with larger sample sizes and fine-mapping studies are needed to clarify the role of AFF1 in the genetic basis of RA.
Descritores: Artrite Reumatoide/genética
Proteínas de Ligação a DNA/genética
Predisposição Genética para Doença/genética
Polimorfismo Genético/genética
Fatores de Elongação da Transcrição/genética
-Grupo com Ancestrais do Continente Asiático
Estudos de Casos e Controles
Frequência do Gene
Genótipo
Limites: Seres Humanos
Masculino
Feminino
Meia-Idade
Responsável: BR1.1 - BIREME


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Id: biblio-888954
Autor: Gu, QL; Han, Y; Lan, YM; Li, Y; Kou, W; Zhou, YS; Hai, XJ; Yan, B; Ci, CH.
Título: Association between polymorphisms in the APOB gene and hyperlipidemia in the Chinese Yugur population
Fonte: Braz. j. med. biol. res = Rev. bras. pesqui. méd. biol;50(11):e6613, 2017. tab.
Idioma: en.
Projeto: National Natural Science Foundation; . Gansu Provincial Natural Science Foundation; . Northwest University.
Resumo: We investigated the influence of apolipoprotein B gene (APOB) variants on the risk of hyperlipidemia (HL) in 631 middle-aged and elderly members of the Chinese Yugur population (HL, n=336; normolipidemia, n=295). APOB polymorphisms were identified using mass spectrometry, and five single nucleotide polymorphisms (rs1042034, rs2163204, rs512535, rs676210, and rs679899) and serum lipids were further analyzed. rs1042034 and rs676210 were significantly associated with HL (P<0.05). Compared with the GG or AA genotype, individuals with AG and AG+AA in rs1042034 and with AG and AG+GG in rs676210 had a 1.67-fold (95%CI=1.20-2.33),1.63-fold (95%CI=1.19-2.24), 1.72-fold (95%CI=1.24-2.40), and 1.67-fold (95%CI=1.21-2.291) increased risk of high HL, respectively. rs2163204 was in strong linkage disequilibrium with rs1042034, rs676210, and rs679899, and strong disequilibrium was observed between rs1042034 and rs676210 (D′>0.9). Compared with the GTGAA haplotype, haplotypes ATGGA and ATAGG were more strongly associated with HL [odds ratio (OR)=1.46, 95%CI=0.02-2.11; OR=1.63, 95%CI=1.03-2.60, respectively]. The risk factors age (P=0.008), body mass index (P<0.0001), GA+GG genotype in rs676210 (P=0.009), and alcohol consumption (P=0.056) contributed strongly to HL development. The A allele of rs1042034 and the G allele of rs676210 may thus predispose middle-aged and elderly members of the Chinese Yugur population to HL in combination with other genetic or nutritional factors, and could be used as new genetic markers for HL screening.
Descritores: Apolipoproteínas B/genética
Hiperlipidemias/genética
Polimorfismo de Nucleotídeo Único
-Grupo com Ancestrais do Continente Asiático/genética
Estudos de Casos e Controles
China/etnologia
Frequência do Gene
Estudos de Associação Genética
Haplótipos
Hiperlipidemias/etnologia
Modelos Lineares
Lipídeos/sangue
Medição de Risco
Fatores de Risco
Limites: Seres Humanos
Masculino
Feminino
Meia-Idade
Idoso
Idoso de 80 Anos ou mais
Responsável: BR1.1 - BIREME


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Id: biblio-839304
Autor: Wei, YL; Tian, Q; Zhao, XX; Qiu, GZ; Xu, Y.
Título: Association between MFN2 gene polymorphisms and the risk and prognosis of acute liver failure: a case-control study in a Chinese population
Fonte: Braz. j. med. biol. res = Rev. bras. pesqui. méd. biol;50(6):e5758, 2017. tab, graf.
Idioma: en.
Resumo: This study aimed to determine the role of mitofusin 2 (MFN2) gene polymorphisms in the risk and prognosis of acute liver failure (ALF). A total of 298 blood samples were collected from 138 ALF patients (case group) and 160 healthy participants (control group). Coagulation function, glutamic pyruvic transaminase (GPT), glutamic oxaloacetic transaminase (GOT), total bilirubin (TB), blood ammonia and lactic acid (LA) were measured. The predictive evaluation of MFN2 gene polymorphisms in the risk and prognosis of ALF patients was estimated using Kaplan-Meier survival analysis, haplotype analysis, binary logistic regression analysis and Cox regression analysis. Higher levels of GPT, GOT, TB, blood ammonia and LA were observed in ALF patients with the GG genotype of rs873457 or the TT genotype of rs4846085 than in those with the CC genotype of these two SNPs. The GTACAGC and GTGTGGC haplotypes were a protective factor and a risk factor for ALF, respectively. Blood ammonia and LA levels were independent risk factors and the CC genotype of rs873457 and the CC genotype of rs4846085 were protective factors for ALF. ALF patients with the GG genotype of rs873457 or the TT genotype of rs4846085 had a lower survival rate than those with other genotypes of these two SNPs. The rs4846085 and rs873457 polymorphisms were both independent factors affecting the prognosis of ALF patients. MFN2 gene polymorphisms (rs873457, rs2336384, rs1474868, rs4846085 and rs2236055) may be associated with ALF and the rs873457 and rs4846085 polymorphisms are correlated with the risk and prognosis of ALF.
Descritores: GTP Fosfo-Hidrolases/genética
Falência Hepática Aguda/genética
Proteínas Mitocondriais/genética
Polimorfismo de Nucleotídeo Único
-Amônia/sangue
Grupo com Ancestrais do Continente Asiático/genética
Estudos de Casos e Controles
China
Frequência do Gene/genética
Predisposição Genética para Doença/genética
Genótipo
Hepatite A/genética
Estimativa de Kaplan-Meier
Ácido Láctico/sangue
Falência Hepática Aguda/sangue
Fatores de Risco
Análise de Sobrevida
Limites: Seres Humanos
Masculino
Feminino
Adulto
Meia-Idade
Adulto Jovem
Responsável: BR1.1 - BIREME


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Id: lil-797894
Autor: Zhang, Y; Zhang, F; Chen, D; Lü, Q; Tang, L; Yang, C; Lei, M; Tong, N.
Título: A novel homozygous mutation in the solute carrier family 12 member 3 gene in a Chinese family with Gitelman syndrome
Fonte: Braz. j. med. biol. res = Rev. bras. pesqui. méd. biol;49(11):e5261, 2016. tab, graf.
Idioma: en.
Resumo: Loss of function of mutated solute carrier family 12 member 3 (SLC12A3) gene is the most frequent etiology for Gitelman syndrome (GS), which is mainly manifested by hypokalemia, hypomagnesemia and hypocalciuria. We report the genetic characteristics of one suspicious Chinese GS pedigree by gene sequencing. Complete sequencing analysis of the SLC12A3 gene revealed that both the proband and his elder sister had a novel homozygous SLC12A3 mutation: c.2099T>C and p.Leu700Pro. Moreover, the SLC12A3 genes of his mother and daughter encoded the same mutated heterozygote. It was noted that in this pedigree, only the proband complained about recurrent episodes of bilateral lower limb weakness over 8 years, while his elder sister, mother and daughter did not present symptoms. The inconsistent clinical features of this pedigree implied that besides diverse phenotypes possibly originated from the same genotype, gender difference may also dominate the variant GS phenotypes. Further genetic and proteomic research are needed to investigate the precise mechanisms of GS, including the study of specific ethnicities.
Descritores: Síndrome de Gitelman/genética
Homozigoto
Mutação/genética
Membro 3 da Família 12 de Carreador de Soluto/genética
-Grupo com Ancestrais do Continente Asiático
Síndrome de Gitelman/diagnóstico
Linhagem
Fenótipo
Limites: Seres Humanos
Masculino
Feminino
Adulto Jovem
Tipo de Publ: Relatos de Casos
Responsável: BR1.1 - BIREME



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