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Id: biblio-1285510
Autor: Elfahmi,; Chahyadi, Agus.
Título: The diversity of ursodeoxycholic acid precursors from bile waste of commercially available fishes, poultry and livestock in Indonesia
Fonte: Braz. J. Pharm. Sci. (Online);56:e18094, 2020. tab, graf.
Idioma: en.
Projeto: World Class University Program.
Resumo: Ursodeoxycholic acid (UDCA), a secondary bile acid (BA), has been used as a drug to treat various liver diseases. UDCA is synthesised from cholic or chenodeoxycholic acid (CA/CDCA), two primary BAs frequently used as the starting materials. Nowadays, swine, cattle, and poultry bile are the main sources of those BAs. However, other commercial animals could be promising sources as well. We identified two livestock, two poultries, and eight fishes that are commercially cultivated in Indonesia. Four free BAs including CA, CDCA, deoxycholic acid (DCA), and lithocholic acid (LA) were identified for their occurrences using thin-layer chromatography and high-performance liquid chromatography. CA was detected in cow, duck, red tilapia, gourami, the common carp, and grouper, whereas CDCA was only detected in two poultries and the common carp. The occurrence of DCA was common and abundant in most tested animals. In contrast, the presence of LA was found to be very low in all samples. The biliary bile of tilapia has been found to contain a high abundance of free CA (43% of the total bile). A simple extraction was able to purify CA from biliary bile of tilapia. This is a new promising and competitive source of CA.
Descritores: Bile/efeitos dos fármacos
Cromatografia Líquida de Alta Pressão/métodos
Cromatografia em Camada Delgada/métodos
Indonésia/etnologia
Animais
-Ácido Ursodesoxicólico
Ácido Ursodesoxicólico/antagonistas & inibidores
Ácidos e Sais Biliares/uso terapêutico
Ácido Quenodesoxicólico
Tilápia/classificação
Ácido Cólico/agonistas
Ácido Desoxicólico
Ácido Litocólico
Limites: Animais
Masculino
Feminino
Responsável: BR40.1 - DBD - Divisão de Biblioteca e Documentacão do Conjunto das Químicas


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Id: biblio-1056850
Autor: Anggraini, Luly; Rizal, Mochamad Fahlevi; Indiarti, Ike Siti.
Título: Prevalence of Dental Anomalies in Indonesian Individuals with Down Syndrome
Fonte: Pesqui. bras. odontopediatria clín. integr;19:e5332, 2019. tab.
Idioma: en.
Resumo: Abstract Objective: To determine the frequency distribution of dental anomalies in people with Down syndrome. Material and Methods: This cross-sectional study was developed in Jakarta, Indonesia, and evaluated 174 individuals with Down syndrome aged 14-53 years. Were collected information regarding the tooth number, tooth size, shape, and structure. Descriptive statistics were used to calculate the absolute and relative frequencies. The Pearson chi-square test was used in bivariate analysis. The significance threshold was set at 5% Results: There were 70 female subjects (40.2%) and 104 male subjects (59.8%) with an average age of 19.2 years. In terms of anomalies of tooth number, hypodontia (80.9%), supernumerary teeth (12.4%), and combined hypodontia and supernumerary teeth (12.4%) were identified. In terms of anomalies of tooth size, microdontia (98.8%) is the most common anomaly. Anomalies of tooth shape included fusion (66.67%) and talon's cusp (33.3%), whereas anomalies of tooth structure included enamel hypoplasia (70.8%), enamel hypocalcification (4.2%), combined enamel hypoplasia and hypocalcification (12.5%), and tooth discoloration (12.5%) Conclusion: Individuals with Down syndrome in Jakarta showed a high prevalence of dental anomalies, with hypodontia and microdontia being the most common anomalies showing a tendency to occur predominantly in males.
Descritores: Anormalidades Dentárias/patologia
Dente Supranumerário/cirurgia
Síndrome de Down/patologia
Indonésia/epidemiologia
Anodontia
-Distribuição de Qui-Quadrado
Estudos Transversais/métodos
Estatísticas não Paramétricas
Esmalte Dentário
Limites: Humanos
Masculino
Feminino
Adolescente
Adulto
Pessoa de Meia-Idade
Responsável: BR1264.1 - Biblioteca Setorial Prof Alberto M Campos


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Id: biblio-1127250
Autor: Fernandes, Eder Gatti; Santos, Janice da Silva; Sato, Helena Keico.
Título: Outbreak investigation in cargo ship in times of COVID-19 crisis, Port of Santos, Brazil / Investigação de surto em navio de carga em tempo de COVID-19, Porto de Santos, Brasil
Fonte: Rev. saúde pública (Online);54:34, 2020.
Idioma: en.
Resumo: ABSTRACT In February 2020, a Chinese cargo ship docked at the Port of Santos with reports of crew members with a feverish and respiratory condition. A team was gathered to verify the existence of suspected cases of COVID-19 inside the vessel and define its clearance. All 25 crew members were interviewed, and no suspected cases were found. The vessel was then cleared for port activities. The investigation resulted from the implementation of the contingency plan to face a public health emergency of international importance and several surveillance entities cooperated.

RESUMO Em fevereiro de 2020, um navio de carga vindo da China atracou no Porto de Santos com relato de tripulantes com quadro febril e respiratório. Uma equipe foi mobilizada para verificar a existência de casos suspeitos de COVID-19 dentro da embarcação e definir a liberação da embarcação no porto. Todos os 25 tripulantes foram entrevistados e não foram encontrados casos suspeitos. Então a embarcação foi liberada para atividades no porto. A investigação resultou da aplicação do plano de contingência diante de uma emergência de saúde pública de importância internacional e houve a colaboração de diversas entidades de vigilância.
Descritores: Pneumonia Viral/prevenção & controle
Navios
Controle de Doenças Transmissíveis/métodos
Surtos de Doenças/prevenção & controle
Infecções por Coronavirus/prevenção & controle
Pandemias/prevenção & controle
-Brasil
China/etnologia
COVID-19
Indonésia/etnologia
Pessoa de Meia-Idade
Limites: Humanos
Masculino
Adulto
Adulto Jovem
Responsável: BR1.1 - BIREME


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Id: biblio-1056879
Autor: Gofur, Nanda Rachmad Putra; Nurdiana, Nurdiana; Handono, Kusworini; Kalim, Handono.
Título: Periodontal Tissue Condition on Systemic Lupus Erythematosus Patients: A Clinical Study
Fonte: Pesqui. bras. odontopediatria clín. integr;20:e5094, 2020. tab, graf.
Idioma: en.
Projeto: Ministry of Research, Technology and Higher Education of the Republic of Indonesia.
Resumo: Abstract Objective: To evaluate periodontal tissue condition on systemic lupus erythematosus (SLE) patients and its characteristics. Material and Methods: This descriptive and cross-sectional study involved 61 SLE patients. Clinical examination of the oral cavity was performed using periodontal index (PI), gingival index (GI), clinical attachment loss (CAL) and number of loose teeth. Also, we evaluated SLE duration, treatment duration, ethnics, marital status, educational background, family income, and occupation. Results: In the evaluation of periodontal tissue, 93.4% had bleeding on probing, 80.3% clinical attachment loss, and 16.3% loose teeth. A total of 54 patients (88.5%) with SLE had periodontitis. Seven subjects had no periodontitis, 11 mild periodontitis, 29 moderate periodontitis and 14 severe periodontitis. Mean Periodontal Index score, Gingival Index, Clinical Attachment Loss (mm), and the number of mobility teeth, Plaque Index and Calculus Index respectively were 2.66 ± 1.20, 1.95 ± 1.02, 0.75 ± 0.59 mm, 1,49 ± 1.77. There was a significant difference in periodontal index score, shown periodontitis between employment and unemployment subjects (p=0.004) and a moderate correlation between periodontitis and occupation. Conclusion: Periodontitis found as manifestations SLE patients, followed by bleeding on probing and loose teeth. Its characteristics is playing a role in periodontitis in SLE patients.
Descritores: Tecido Periapical
Periodontite/diagnóstico
Índice Periodontal
Estudos Clínicos como Assunto/métodos
Lúpus Eritematoso Sistêmico
-Doenças Periodontais/diagnóstico
Estudos Transversais/métodos
Interpretação Estatística de Dados
Indonésia/epidemiologia
Limites: Humanos
Feminino
Adolescente
Adulto
Pessoa de Meia-Idade
Tipo de Publ: Estudo de Avaliação
Responsável: BR1264.1 - Biblioteca Setorial Prof Alberto M Campos


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Id: biblio-1056880
Autor: Iskandar, Regina Purnama Dewi; Alida, Alida; Triwardhani, Ari; Narmada, Ida Bagus; Hanum, Faizah; Kusumo, Arief Haryo; Nidom, Chairul Anwar; Sudjarwo, Sri Agus.
Título: Soluble Human Leukocyte Antigen Molecules Detected in Orofacial Cleft Patients: A Case-Control Study
Fonte: Pesqui. bras. odontopediatria clín. integr;20:e5096, 2020. tab.
Idioma: en.
Projeto: Universitas Airlangga Research Grant Fund.
Resumo: Abstract Objective: To compare soluble HLA-C and HLA-DR molecules present in the plasma of orofacial cleft and non-orofacial cleft populations. Material and Methods: Orofacial cleft patients were recruited using an accidental sampling approach (n=15). Peripheral blood was collected from the participants and processed for Enzyme Linked Immunosorbent Assay (ELISA) against HLA-C and HLA-DR with specific antibodies. The absorbance was calculated utilizing ELISA reader. Data were statistically analyzed using an independent t-test to compare the disease and control groups. Results: The levels of soluble HLA-C and HLA-DR were significantly higher in the diseased group compared to the control group (p<0.05). Conclusion: The role of HLA molecules in non-communicable disease and congenital anomalies, particularly orofacial cleft, remains speculative despite the positive results of this study and those of previous investigations. It suggests that the variables examined may affect specific pathways involved in the pathogenesis of orofacial cleft, and predispose the individuals concerned to the oral cleft.
Descritores: Antígenos HLA-C
Antígenos HLA-DR
Estudos de Casos e Controles
Patogênese Homeopática
Fenda Labial/patologia
-Ensaio de Imunoadsorção Enzimática
Interpretação Estatística de Dados
Indonésia
Limites: Humanos
Feminino
Criança
Adolescente
Tipo de Publ: Estudo Comparativo
Responsável: BR1264.1 - Biblioteca Setorial Prof Alberto M Campos


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Id: biblio-1101285
Autor: Nugraha, Alexander Patera; Narmada, Ida Bagus; Sitasari, Putri Intan; Inayati, Fidiyah; Wira, Rahendra; Triwardhani, Ari; Hamid, Thalca; Ardani, I Gusti Aju Wahju; Djaharu'ddin, Irwadi; Rahmawati, Dwi; Iskandar, Regina Purnama Dewi.
Título: High Mobility Group Box 1 and Heat Shock Protein-70 Expression Post (-)-Epigallocatechin-3-Gallate in East Java Green Tea Methanolic Extract Administration During Orthodontic Tooth Movement in Wistar Rats
Fonte: Pesqui. bras. odontopediatria clín. integr;20:e5347, 2020. graf.
Idioma: en.
Projeto: Penelitian Dosen Pemula.
Resumo: Abstract Objective: To investigate the expression of High Mobility Group Box 1 (HMGB1) and Heat Shock Protein-70 (HSP-70) during orthodontic tooth movement (OTM) after (-)- Epigallocatechin-3-Gallate (EGCG) in East Java Green Tea (Camelia Sinensis) Methanolic Extract (GTME) administration in vivo. Material and Methods: 28 Wistar rats (Rattus Novergicus) was used and divided into 4 groups accordingly: K- without EGCG and OTM; K+ with OTM, without EGCG for 14 days; T1with OTM for 14 days and EGCG for 7 days; treatment group 2 (T2) with OTM and EGCG for 14 days. OTM animal model was achieved through the installation of the OTM device by means of NiTi close coil spring with 10g force placed between the first incisor and first maxillary molars. The samples were terminated on Day 14. The pre-maxillary was isolated for the immunohistochemical examination. Analysis of Variance (ANOVA) then continued with Tukey Honest Significant Difference (HSD) (p<0.05) was performed to analyze the data. Results: The highest HMGB1 and HSP-70 expression were found in the K+ group pressure side, meanwhile the lowest HMGB1 and HSP-70 expression were found in K- group tension side in the alveolar bone. There was a significant decrease of HMGB1 and HSP-70 expression in T2 compared to T1 and K+ with significant between groups (p<0.05; p=0.0001). Conclusion: The decreased expression of HMGB1 and HSP-70 in alveolar bone of OTM wistar rats due to post administration of GTME that consisted EGCG.
Descritores: Técnicas de Movimentação Dentária/instrumentação
Ratos Wistar
Proteína HMGB1
Proteínas de Choque Térmico
Antioxidantes/uso terapêutico
-Chá
Osso e Ossos
Imuno-Histoquímica
Análise de Variância
Modelos Animais
Incisivo
Indonésia
Dente Molar
Limites: Animais
Ratos
Tipo de Publ: Estudo Comparativo
Responsável: BR1264.1 - Biblioteca Setorial Prof Alberto M Campos


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Id: biblio-1101291
Autor: Machmud, Edy; Ruslin, Muhammad; Waris, Rahmat; Asse, Rustan Ambo; Qadafi, Andi Muamar; Achmad, Harun.
Título: Effect of the Application of Chlorella Vulgaris Ointment to the Number of Fibroblast Cells as an Indicator of Wound Healing in the Soft Tissue of Pig Ears
Fonte: Pesqui. bras. odontopediatria clín. integr;20:e5012, 2020. tab, graf.
Idioma: en.
Resumo: Abstract Objective: To analyze the clinical and histological condition of Chlorella vulgaris ointment extract smearing on wound healing. Material and Methods: The sample consisted of 9 pigs by making 4 incisions on the pig's right ear measuring 2cm x 1cm and applying Chlorella vulgaris ointment in 3 concentrations namely 5%, 10%, 15% and without ointment application as the control group. Furthermore, the observation of the clinical condition of wounds divided into 4 time periods (day 1, 3, 7 and 14). After completing clinical observations based on time period, the skin of the pig's ear was taken by cutting in the area that had been made injured. Skin tissue extraction carried out under inhalation and local anesthesia. The tissue pieces are then processed in the anatomical pathology laboratory to become 36 slide preparations. The clinical trial assessment was done using parameters of wound moisture, color of wound and scab wound. Whereas for histological examination was done by looking at the number of fibroblast cells in the CX31 light microscope with 40x magnification. ANOVA and Kruskal Wallis tests were used. Results: In the clinical observation conditions there were significant differences between the treatment group and the control group as well as the number of fibroblast cells there were significant differences between the 3 concentrations of Chlorella vulgaris extract ointment and the per time period control group. Conclusion: Chlorella vulgaris extract ointment containing 15% extract gives the best results in accelerating the wound healing process in the pig's ear seen from wound healing and increased number of fibroblast cells.
Descritores: Cicatrização
Ferimentos e Lesões
Chlorella vulgaris
Fibroblastos
Anestesia Local
-Suínos
Análise de Variância
Modelos Animais
Indonésia
Limites: Animais
Tipo de Publ: Estudo de Avaliação
Responsável: BR1264.1 - Biblioteca Setorial Prof Alberto M Campos


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Id: biblio-1135566 LILACS-Express
Autor: Akbar, Fuad Husain; Pasinringi, Syahrir; Awang, Abdul Hair.
Título: Assessment of Patient Satisfaction Level to Dental Health Care Services in Indonesia
Fonte: Pesqui. bras. odontopediatria clín. integr;20:e4825, 2020. tab.
Idioma: en.
Resumo: Abstract Objective: To know the level of patient satisfaction with dental healthcare services in Bantaeng, Indonesia. Material and Methods: This pilot pathfinder survey was conducted at Dental and Oral Health Services in Bantaeng and Pa'jukukang Sub-districts of Bantaeng Regency of South Sulawesi Indonesia. The Short-Form Patient Satisfaction Questionnaire (PSQ-18) scaled was used and it consists of 18 questions and seven subscales. The t-test and ANOVA were used with a significance level set at 5% (p<0.05). Results: The female participation (72.8%) was greater than the male (27.2). Regarding age, 74.6% were <40 years, 21.1% were between 40-60 years old and 4.4% were over 60 years old. On the subscale of technical quality, there was significant value in the age variable (p=0.45), education level (p=0.031), job (p=0.026), waiting time (p=0.46), distance to dentist=0.026), and location (p=0.007). There were significant values on the interpersonal aspect subscale that were present at age (p=0.016), education level (p=0.038), and occupation (p=0.007). The highest satisfaction score was found on the technical quality subscale (13.04 ± 1.75) and the lowest satisfaction score was seen on the general satisfaction subscale (4.11 ± 1.75). There was a significant difference between the value of patient satisfaction with age, education, and occupation. Conclusion: Patients from the District Bantaeng and Pa'jukukang Bantaeng regency of South Sulawesi were more satisfied with the service provided. The highest satisfaction score was found on the technical quality subscale and the lowest satisfaction score was found in the general satisfaction subscale.
Descritores: Saúde Bucal
Satisfação do Paciente
Assistência Odontológica Integral
Indicadores de Qualidade em Assistência à Saúde/normas
-Inquéritos e Questionários
Análise de Variância
Serviços de Saúde Bucal
Indonésia/epidemiologia
Responsável: BR1264.1 - Biblioteca Setorial Prof Alberto M Campos


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Id: biblio-1101296
Autor: Luthfi, Muhammad; Juliastuti, Wisnu Setyari; Risky, Yuniar Aliyah.
Título: Angiogenesis of Extracted Tooth Wound on Wistar Rats After Application of Okra (Abelmoschus esculentus) Gel Extract
Fonte: Pesqui. bras. odontopediatria clín. integr;20:e5087, 2020. tab, graf.
Idioma: en.
Resumo: Abstract Objective: To analyze angiogenesis in the post-extracted tooth of Wistar rats after application of okra (Abelmoschus esculentus) extract. Material and Methods: A total of 18 rats were divided into two groups (control and treatment). Okra extract with a concentration of 30% in gel form was applied on the post-extraction socket of the treatment group. The rats were sacrificed on day-3, day-5, and day-7 after tooth extraction. The newly-formed blood vessels were counted and statistically analyzed by means of One Way ANOVA and Tukey HSD with a significance level set at 5%. Results: The newly-formed capillaries of the control group (4.67 ± 1.53) on day-3 were lower than the treatment group (9.00 ± 1.00). The newly-formed capillaries recorded from the control group, both in day-5 (9.33 ± 1.53) and day-7 (8.67 ± 1.53) were lower than the treatment group, which started to decreased from day-5 (13.67 ± 1.53) to day-7 (12.33 ± 0.58). Significant differences were found in treatment group, on day-3 compared to day-5 (p=0.005), and on day-3 to day-7 (p=0.024). Conclusion: Okra extract in gel form at 30% concentration can increase the angiogenesis during the wound healing process of the extracted tooth on Wistar rats.
Descritores: Extração Dentária
Cicatrização
Ferimentos e Lesões
Ratos Wistar
Abelmoschus
-Análise de Variância
Estatísticas não Paramétricas
Indonésia
Limites: Animais
Ratos
Tipo de Publ: Estudo Comparativo
Responsável: BR1264.1 - Biblioteca Setorial Prof Alberto M Campos


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Id: biblio-1101300
Autor: Bramantoro, Taufan; Basiroh, Eris; Berniyanti, Titiek; Setijanto, R. Darmawan; Irmalia, Wahyuning Ratih.
Título: Intention and Oral Health Behavior Perspective of Islamic Traditional Boarding School Students Based on Theory of Planned Behavior
Fonte: Pesqui. bras. odontopediatria clín. integr;20:e4977, 2020. tab, graf.
Idioma: en.
Resumo: Abstract Objective: To analyze the correlation of the students in an Islamic boarding school intention toward oral health behavior by means of the Theory of Planned Behavior (TPB) approach. Material and Methods: A cross-sectional analytic study was conducted on 153 students of an Islamic boarding school who fulfilled the criterion. Data were obtained by a questionnaire and clinical examination. Data were presented as mean and standard deviation. Results: The highest score of the variable that affects behavior recorded from both male and female respondents was Subjective Norm (57.288 ± 12.828), followed by Attitude (25.627 ± 4.144). Meanwhile, the lowest score that affects behavior was Oral Health Knowledge (3.179 ± 1.402). All study variables, according to the theory of planned behavior, such as knowledge, attitude, subjective norm, perceived behavior control, and intention had significant value to predict and assess behavior with p<0.05. Conclusion: Attitude, subjective norms, perceived behavioral control, and oral health knowledge in Private Boarding School's Santris influence the intention to improve oral hygiene behavior.
Descritores: Higiene Bucal
Estudantes
Comportamentos Relacionados com a Saúde
Conhecimentos, Atitudes e Prática em Saúde
Saúde Bucal
-Modelos Lineares
Estudos Transversais/métodos
Análise Multivariada
Inquéritos e Questionários
Indonésia/epidemiologia
Limites: Humanos
Masculino
Feminino
Criança
Adolescente
Responsável: BR1264.1 - Biblioteca Setorial Prof Alberto M Campos



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