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Id: biblio-1130524
Autor: Wagle, Prasad; Narkhede, Rajvilas; Desai, Gunjan; Pande, Prasad; Kulkarni, D R; Varty, Paresh.
Título: Surgical management of large hepatocellular carcinoma: the first single-center study from western india / Manejo cirúrgico de grandes carcinomas hepatocelulares: primeiro estudo de um único centro da índia ocidental
Fonte: ABCD arq. bras. cir. dig;33(2):e1505, 2020. tab, graf.
Idioma: en.
Resumo: ABSTRACT Background: Majority of patients with large size HCC (>10 cm) are not offered surgery as per Barcelona Clinic Liver Cancer (BCLC) criteria and hence, their outcomes are not well studied, especially from India, owing to a lower incidence. Aim: To analyze outcomes of surgery for large HCCs. Methods: This retrospective observational study included all patients who underwent surgery for large HCC from January 2007 to December 2017. The entire perioperative and follow up data was collected and analyzed. Results: Nineteen patients were included. Ten were non-cirrhotic; 16 were BCLC grade A; one BCLC grade B; and two were BCLC C. Two cirrhotic and three non-cirrhotic underwent preoperative sequential trans-arterial chemoembolization and portal vein embolization. Right hepatectomy was the most commonly done procedure. The postoperative 30-day mortality rate was 5% (1/19). Wound infection and postoperative ascites was seen in seven patients each. Postoperative liver failure was seen in five. Two cirrhotic and two non-cirrhotic patients had postoperative bile leak. The hospital stay was 11.9±5.4 days (median 12 days). Vascular invasion was present in four cirrhotic and five non-cirrhotic patients. The median follow-up was 32 months. Five patients died in the follow-up period. Seven had recurrence and median recurrence free survival was 18 months. The cumulative recurrence free survival was 88% and 54%, whereas the cumulative overall survival was 94% and 73% at one and three years respectively. Both were better in non-cirrhotic; however, the difference was not statistically significant. The recurrence free survival was better in patients without vascular invasion and the difference was statistically significant (p=0.011). Conclusion: Large HCC is not a contraindication for surgery. Vascular invasion if present, adversely affects survival. Proper case selection can provide the most favorable survival with minimal morbidity.

RESUMO Racional: A maioria dos pacientes com CHC de grande porte (>10 cm) não tem indicação cirúrgica conforme os critérios do Barcelona Clinic Liver Cancer (BCLC) e, portanto, seus resultados não são bem estudados, principalmente na Índia, devido a uma menor incidência. Objetivo: Analisar os resultados da cirurgia para HCCs de grande porte. Métodos: Este estudo observacional retrospectivo incluiu todos os pacientes submetidos à cirurgia para grandes CHC de janeiro de 2007 a dezembro de 2017. Todos os dados perioperatórios e de acompanhamento foram coletados e analisados. Resultados: Dezenove pacientes foram incluídos. Dez não eram cirróticos; 16 eram BCLC grau A; um BCLC grau B; e dois eram BCLC C. Dois cirróticos e três não-cirróticos foram submetidos à quimioembolização transarterial sequencial pré-operatória e embolização da veia porta. Hepatectomia direita foi o procedimento mais comumente realizado. A taxa de mortalidade pós-operatória em 30 dias foi de 5% (1/19). Infecção da ferida e ascite pós-operatória foram observadas em sete pacientes cada. Insuficiência hepática pós-operatória foi observada em cinco. Dois pacientes cirróticos e dois não cirróticos apresentaram vazamento de bile no pós-operatório. O tempo de internação foi de 11,9±5,4 dias (mediana de 12 dias). A invasão vascular estava presente em quatro pacientes cirróticos e cinco não cirróticos. O acompanhamento médio foi de 32 meses. Cinco pacientes morreram no período de acompanhamento. Sete tiveram recorrência e sobrevida mediana livre de recorrência foi de 18 meses. A sobrevida livre de recorrência cumulativa foi de 88% e 54%, enquanto a sobrevida global cumulativa foi de 94% e 73% em um e três anos, respectivamente. Ambos eram melhores em não-cirróticos; no entanto, a diferença não foi estatisticamente significante. A sobrevida livre de recidiva foi melhor nos pacientes sem invasão vascular e a diferença foi estatisticamente significante (p=0,011). Conclusão: CHC grande não é contraindicação para cirurgia. Invasão vascular, se presente, afeta adversamente a sobrevida. Seleção adequada de casos pode fornecer sobrevida mais favorável com morbidade mínima.
Descritores: Carcinoma Hepatocelular/cirurgia
Neoplasias Hepáticas/cirurgia
-Estudos Retrospectivos
Resultado do Tratamento
Hepatectomia
Índia
Recidiva Local de Neoplasia/epidemiologia
Estadiamento de Neoplasias
Limites: Humanos
Masculino
Feminino
Adulto
Pessoa de Meia-Idade
Idoso
Tipo de Publ: Estudo Observacional
Responsável: BR1.1 - BIREME


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Id: biblio-1284327
Autor: GeoHazards International.
Título: Identifying earthquake-unsafe schools and setting priorities to make them safe: a case study In Gujarat, India.
Fonte: California; GeoHazards International; Feb. 3, 2005. 40 p. tab.
Idioma: en.
Resumo: After the January 26, 2001 Gujarat Earthquake, GeoHazards International (GHI) was concerned about the risk of school buildings in the largest Gujarat cities and asked the Volunteers for India Development and Empowerment (VIDE) and NGOs Kobe to help fund a study that would identify earthquake-unsafe school buildings in Ahmedabad, Baroda and Surat. VIDE and NGOs Kobe agreed to help. GHI worked with its Indian partner organization, SEEDS, to evaluate 153 schools: 42 in Ahmedabad, 58 in Baroda, and 53 in Surat. The schools included different structural types, served students from a variety of educational and economic levels, and were widely dispersed within each city. GHI found that the earthquake risk of the schools in all three cities is significant, and recommends that the authorities responsible for these schools take steps to reduce the risk. GHI further recommends that these authorities initiate comprehensive school earthquake risk mitigation programs. GHI and SEEDS will meet with officials in these three cities to discuss these findings and follow-up actions. After this meeting, this report will be revised.
Descritores: Instituições Acadêmicas
Efeitos de Desastres nas Edificações
Terremotos
Colapso Estrutural
-Índia
Responsável: BR1.1 - BIREME


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Id: lil-676142
Autor: Singh, M; Mahajan, A.
Título: An anatomical study of variations of sacral hiatus in sacra of north Indian origin and its clinical significance / Estudio anatómico de las variaciones del hiato sacro en sacros del norte de la India y su significancia clínica
Fonte: Int. j. morphol;31(1):110-114, mar. 2013. ilus.
Idioma: en.
Resumo: Sacrum is formed by the fusion of five sacral vertebrae and forms the lower part of vertebral column. The opening present at the lower end of sacral canal is known as sacral hiatus. Anatomical variations in morphology and morphometry of sacral hiatus are important clinically as well as surgically. 159 dry clean human Sacra were taken from Department of Anatomy, Sri Guru Ram Das Institute of Medical Sciences and Research Vallah (Amritsar). Various shapes of sacral hiatus were observed which included inverted U (42.95%), inverted V (27.51%), irregular (16.10%), dumbbell (11.40%) and bifid (2.01%). The apex of sacral hiatus was commonly found at the level of 4th sacral vertebra in 56.36%. The mean length of sacral hiatus was 22.69 mm. The mean anteroposterior diameter of sacral canal at the apex of sacral hiatus was 6.49 mm. Narrowing of sacral canal at the apex of sacral hiatus (diameter less than 3 mm) was observed to be high (5.36%). The knowledge of anatomical variations of dimensions of sacral hiatus is important while doing caudal epidural block and it may help to improve its success rate.

El sacro está conformado por la fusión de las cinco vértebras sacras, y forma la parte inferior de la columna vertebral. La abertura presente en el extremo inferior del canal sacro se conoce como hiato sacro. Las variaciones anatómicas en la morfología y la morfometría del hiato sacro son importantes clínica y quirúrgicamente. Fueron utilizados 159 sacros humanos, limpios y secos, del Departamento de Anatomía, Sri Guru Ram Das Instituto de Ciencias Médicas e Investigación Vallah (Amritsar). Fueron observadas varias formas de hiato sacro: U invertida (42,95%), V invertida (27,51%), irregular (16,10%), de pesa (11,40%) y bífida (2,01%). El ápice del hiato sacro se encuentra comúnmente a nivel de la cuarta vértebra sacra en el 56,36%. La longitud media de hiato sacro fue 22,69 mm. El diámetro medio anteroposterior del canal sacro en el ápice del hiato sacro fue 6,49 mm. El estrechamiento del canal sacro en el ápice del hiato sacro (diámetro inferior a 3 mm) fue alto (5,36%). El conocimiento de las variaciones anatómicas de las dimensiones del hiato sacro es importante para el bloqueo epidural caudal y puede ayudar a mejorar su tasa de éxito.
Descritores: Sacro/anatomia & histologia
Variação Anatômica
-Coluna Vertebral
Índia
Limites: Humanos
Responsável: CL1.1 - Biblioteca Central


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Id: biblio-1254267
Autor: Vashistha, Vishal; Choudhari, Chandrashekhar; Garg, Avneet; Gupta, Aditi; Parthasarathy, Gopanandan; Jain, Deepali; Madan, Karan; Hadda, Vijay; Khilnani, GC; Guleria, Randeep; Mohan, Anant.
Título: The time required to diagnose and treat lung cancer in Delhi, India: an updated experience of a public referral center
Fonte: Appl. cancer res;39:1-9, 2019. ilus, tab.
Idioma: en.
Resumo: Background: Delays that postpone the evaluation and management of malignancy may lead to considerable morbidity. The primary objective of this study was to assess the time required to diagnose and treat lung cancer at an Indian public referral center that predominantly serves lower-income patients. Methods: A review of patients diagnosed with lung cancer between January 2008 and December 2016 was completed. We computed the median time intervals and inter-quartile ranges between symptom onset, definitive diagnostic investigation, confirmed histologic diagnosis, and chemotherapy initiation. Median intervals were correlated with baseline demographics and disease characteristics using Kruskal-Wallis test. Results: One thousand, three hundred and-seventy patients were selected. A majority (94.5%) with non-small cell lung cancer were diagnosed with advanced disease. After developing symptoms, patients required 101 [56­168] days to undergo a definitive diagnostic study, 107 [60­173] days to confirm a diagnosis, and 126 [85­196.8] days to initiate treatment. Patients who were previously treated for tuberculosis required more time to receive chemotherapy compared to those who were not (187 [134­261.5] days vs. 113 [75­180] days, p < 0.0001). A specialty Lung Cancer Clinic was implemented in 2012, and the mean referrals per month increased nearly four-fold (p < 0.0001), but the time required to administer treatment was not shortened. Conclusion: Among lower-income Indian patients, the most prominent delays occur prior to diagnosis. Efforts should be directed toward encouraging physicians to maintain a high index of clinical suspicion and educating patients to report concerning symptoms as early as possible.
Descritores: Neoplasias Pulmonares/diagnóstico
Neoplasias Pulmonares/terapia
-Índia
Limites: Humanos
Adulto
Responsável: BR30.1 - Biblioteca


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Id: biblio-1254282
Autor: Bhambal, Annette M; Bhambal, Ajay; Shukla, U S; Dhingra, Aashna.
Título: Effectiveness of Pentoxifylline in the treatment of oral submucous fibrosis patients: a case-control study
Fonte: Appl. cancer res;39:1-9, 2019. tab.
Idioma: en.
Resumo: Background: Oral submucous fibrosis (OSMF) is a potentially malignant disorder largely seen in the South-Asian countries where areca nut is found to be the main predisposing factor. Pentoxifylline, a methylxanthine derivative, has vasodilating properties and is believed to increase the vascularity of the mucosal layer. This study was designed to determine the effect of pentoxifylline (Trental) on the clinical progression of oral submucous fibrosis. Aim: The present study was aimed to evaluate the effectiveness of drug pentoxifylline in the management of OSMF and to correlate the clinical parameters evaluated before and after treatment. Methods: Study Design: This investigation was conducted as a case-control study incorporating a Control Group in comparison to a Study Group where pentoxifylline 400 mg was administered 3 times daily, as coated, sustainedrelease tablets for prescribed for 3 months. The stipulated period for the study was 8 months and a total of 80 cases of oral submucous fibrosis (40 test subjects and 40 controls) were included in this study and 100% acquiescence was reported at the end of the test period. Results: Mild dizziness and gastric irritation were the only untoward symptoms reported in 2 of the volunteers in the study group during this trial. These were managed by diet protocols. A review of the patients and controls was done at an interval of every 4 weeks for 3 months. The subjective and objective measurements were recorded. The follow-up data at each visit concerning each other and to base-line values were calibrated using nonparametric tests of the Chi-Square test and Mann-Whitney. Significant comparisons with regard to improvement were recorded as objective criteria of mouth opening (u value =1.137, p = 0.260), tongue protrusion (u value = 0.262, p = 0.794 and cheek flexibility (u value =0.990, p = 0.326). Subjective symptoms of burning sensation of mouth (U value = 2.673, p = 0.008), pain on opening the mouth (U value = 4.320, p < 0.0001), difficulty in swallowing and difficulty in the speech were also recorded. Conclusion: This study showed the effectiveness of pentoxifylline as an additional therapy in the routine management of oral submucous fibrosis.
Descritores: Fibrose Oral Submucosa/tratamento farmacológico
Pentoxifilina
-Terapêutica
Estudos Transversais
Índia
Limites: Humanos
Responsável: BR30.1 - Biblioteca


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Id: biblio-1177412
Autor: Gupta, Verruchi; Singh, Inderpal; Rasool, Shafaq; Verma, Vijeshwar.
Título: Next generation sequencing and microbiome's taxonomical characterization of frozen soil of north western Himalayas of Jammu and Kashmir, India
Fonte: Electron. j. biotechnol;45:30-37, May 15, 2020. ilus, graf.
Idioma: es.
Projeto: Department of Biotechnology, Govt. of India.
Resumo: BACKGROUND: Traditionally, microbial genome sequencing has been restrained to the species grown in pure culture. The development of culture-independent techniques over the last decade allows scientists to sequence microbial communities directly from environmental samples. Metagenomics is the study of complex genome by the isolation of DNA of the whole community. Next generation sequencing (NGS) of metagenomic DNA gives information about the microbial and taxonomical characterization of a particular niche. The objective of the present research is to study the microbial and taxonomical characterization of the metagenomic DNA, isolated from the frozen soil sample of a glacier in the north western Himalayas through NGS. RESULTS: The glacier community comprised of 16 phyla with the representation of members belonging to Proteobacteria and Acidobacteria. The number of genes annotated through the Kyoto Encyclopedia of Genes and Genomes (KEGG), GO, Pfam, Clusters of Orthologous Groups of proteins (COGs), and FIG databases were generated by COGNIZER. The annotation of genes assigned in each group from the metagenomics data through COG database and the number of genes annotated in different pathways through KEGG database were reported. CONCLUSION: Results indicate that the glacier soil taken in the present study, harbors taxonomically and metabolically diverse communities. The major bacterial group present in the niche is Proteobacteria followed by Acidobacteria, and Actinobacteria, etc. Different genes were annotated through COG and KEGG databases that integrate genomic, chemical, and systemic functional information.
Descritores: Microbiologia do Solo
Bactérias/classificação
Sequenciamento de Nucleotídeos em Larga Escala
Microbiota/genética
-Bactérias/isolamento & purificação
Clima Frio
Biologia Computacional
Camada de Gelo
Metagenômica
Genoma Microbiano
Índia
Responsável: CL1.1 - Biblioteca Central


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Id: biblio-1045591
Autor: Kadanakuppe, S; Bhat, PK.
Título: Oral health status and treatment needs of iruligas at ramanagara District, Karnataka, India / Estado de la salud oral y necesidades de tratamiento de los iruligas, en el Distrito de Ramanagara, Karnataka, India
Fonte: West Indian med. j;62(1):73-80, Jan. 2013. ilus, tab.
Idioma: en.
Resumo: OBJECTIVES: To assess the oral health status and treatment needs of Iruliga tribal community residing at Ramanagara District, Karnataka, India. METHODS: The total population of 2605 Iruligas residing at 26 villages of Ramanagara District was included for the study. Data were collected using World Health Organization (WHO) 1997 'Oral Health Assessment Form'. Examination was done under good natural light using a mouth mirror and community periodontal index (CPI) probe. RESULTS: The total study population was 2605, comprising 1545 males and 1060 females in the age group of 1-80 years with the mean age of 30.56 ± 19.51. The majority of Iruligas (79.8%) used chew sticks as an oral hygiene aid. Subjects with leukoplakia were found to be 3 (0.12). The most commonly seen enamel opacity/hypoplasia was diffuse opacity affecting 930 (35.7%) subjects. A mild form of dental fluorosis affected 1658 (63.65%) subjects. Subjects with bleeding were only 4.22%; subjects with calculus were 57.9%; those with shallow pockets (4-5 mm) were 22.0% and subjects with deep pockets (> 6 mm) were 3.67%. The prevalence of dental caries among Iruligas was found to be 7.52%. The mean number of decayed, missing, filled (DMF) permanent teeth per person was 0.55 ± 0.1. Definite malocclusion, which required elective treatment, was noted in 14.1%. Iruligas with need for referral were found to be 29.94% (n = 780) according to the various treatment needs required for different oral diseases. CONCLUSION: This study revealed less prevalence of oral diseases among Iruligas, highlighting the role of good oral health practices prevalent among this isolated population.

OBJETIVOS: Evaluar el estado de salud oral y las necesidades de tratamiento en la comunidad tribal Iruliga, que reside en el Distrito de Ramanagara, Karnataka, India. MÉTODOS: La población total de 2605 Iruligas que residen en 26 aldeas del Distrito de Ramanagara, fue incluida en el estudio. Los datos fueron recogidos usando el Formulario de evaluación de la salud oral (OMS) de 1997. El examen se hizo bajo buena luz natural, usando un espejo bucal, y la sonda Índice Periodontal Comunitario (IPC). RESULTADOS: La población total del estudio fue 2605, y abarcó 1545 varones y 1060 hembras en el grupo etario de 1-80 años, con una edad media de 30.56 ± 19.51. La mayoría de los Iruligas (79.8%) usaban palillos de masticar como medio para la higiene oral. Se halló que los sujetos con leucoplasia oral eran 3 (0.12). La hipoplasia u opacidad del esmalte más común fue la opacidad difusa que afectaba a 930 (35.7%) sujetos. Una forma leve de fluorosis dental afectaba a 1658 (63.65%) de los sujetos. Los sujetos con sangramiento fueron sólo el 4.22%. Los sujetos con cálculo fueron el 57.9%; los que presentaban bolsas poco profundas (4-5 mm) fueron el 22.0% y los sujetos con bolsas profundas (> 6 mm) fueron el 3.67%. Se halló que la prevalencia de las caries dentales entre los Iruligas fue de 7.52%. El número promedio de dientes permanentes con caries, faltantes y obturados (DMF) fue 0.55 ± 0.1. La maloclusión definida, que requirió tratamiento electivo, se hizo evidente en 14.1%. Se halló que los Iruligas con necesidad de ser remitidos fue un 29.94% (n = 780) de acuerdo con las diferentes necesidades de tratamiento requeridas para las diferentes enfermedades orales. CONCLUSIÓN: Este estudio reveló menos prevalencia de enfermedades orales entre los Iruligas, destacando el papel de las buenas prácticas de la salud oral prevalentes entre esta población aislada.
Descritores: Higiene Bucal/estatística & dados numéricos
Saúde Bucal/estatística & dados numéricos
Cárie Dentária/epidemiologia
-Índice Periodontal
Prevalência
Disparidades nos Níveis de Saúde
Índia/epidemiologia
Limites: Humanos
Masculino
Feminino
Lactente
Pré-Escolar
Criança
Adolescente
Adulto
Pessoa de Meia-Idade
Idoso
Idoso de 80 Anos ou mais
Responsável: BR1.1 - BIREME


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Id: biblio-990027
Autor: Choudhary, Om Prakash; Kalita, Pranab Chandra; Konwar, Bedanga; Doley, Probal Jyoti; Kalita, Girin; Kalita, Arup.
Título: Morphological and Applied Anatomical Studies on the Head Region of Local Mizo Pig (Zovawk) of Mizoram / Estudios Morfológicos y Anatómicos Aplicados en la Cabeza de Cerdo Local Mizo (Zovawk) de Mizoram
Fonte: Int. j. morphol;37(1):196-204, 2019. graf.
Idioma: en.
Resumo: SUMMARY: Zovawk is newly identified breed of pig of Mizoram approved by breed registration committee of Indian Council of Agricultural Research (ICAR), New Delhi. This study was designed to provide maximum number of morphometrical parameters of skull and some valuable information on clinically important parameters of Zovawk. The skull of the Zovawk was dolichocephalic according to the cephalic index (53.56±0.11). The supraorbital foramina distance, infraorbital foramina distance, skull length, skull width, cranial length and nasal length of the Zovawk were 3.49±0.01 cm, 6.55±0.01 cm, 28.26±0.03 cm, 15.11±0.26 cm, 13.17±0.04 cm and 13.79±0.02 cm, respectively. The orbital margins were found to be incomplete with bilateral variation among the orbits of both the sides. The distance from the process of alveolar socket of canine tooth to the infraorbital canal and from the latter to the root of the fourth upper premolar alveolar tooth directly ventral to it was 4.77±0.04 cm and 1.20±0.01 cm, respectively in Zovawk. The data are of clinical importance as a guide for tracking the infra-orbital nerve, and necessary for its desensitization during the manipulations in the skin of the upper lip, nostril and face at the level of the foramen. The distance between the lateral end of the alveolus of the third incisor tooth to the mental foramen was 3.57±0.04 cm in Zovawk, which is an important landmark for achieving the location of the mental nerve for the regional nerve block Zovawk. The length and height of the mandible were 25.02±0.09 cm and 10.54±0.07 cm, respectively in Zovawk. The morphometric measurements of the skull and applied anatomy of the head region of the Zovawk provide an important baseline data for further research in the field of applied anatomy.

RESUMEN: Zovawk es una raza de cerdo de Mizoram recientemente identificada, aprobada por el comité de registro de razas del Consejo Indio de Investigación Agrícola (ICAR), Nueva Delhi. Este estudio fue diseñado para proporcionar el número máximo de parámetros morfométricos del cráneo y cierta información valiosa sobre parámetros clínicamente importantes de Zovawk. El cráneo de Zovawk es dolicocefálico según el índice cefálico (53,56 ± 0,11). La distancia de foramina supraorbital, la distancia de foramina infraorbital, la longitud del cráneo, el ancho del cráneo, la longitud craneal y la longitud nasal del Zovawk fueron 3.49 ± 0.01 cm, 6.55 ± 0.01 cm, 28.26 ± 0.03 cm, 15.11 ± 0.26 cm, 13.17 ± 0.04 cm y 13.79 ± 0,02 cm, respectivamente. Se encontró que los márgenes orbitales estaban incompletos con una variación bilateral entre las órbitas de ambos lados. La distancia desde el proceso de la cavidad alveolar del diente canino al canal infraorbitario y desde este último a la raíz del cuarto diente alveolar premolar superior directamente ventral fue de 4.77 ± 0.04 cm y 1.20 ± 0.01 cm, respectivamente, en Zovawk. Los datos son de importancia clínica como guía para el seguimiento del nervio infra-orbital y necesarios para su desensibilización durante las manipulaciones en la piel del labio superior, fosa nasal y cara a nivel del foramen. La distancia entre el extremo lateral del alvéolo del tercer diente incisivo y el foramen mental fue de 3.57 ± 0.04 cm en Zovawk, que es un hito importante para lograr la ubicación del nervio mental para el bloqueo nervioso regional Zovawk. La longitud y la altura de la mandíbula fueron 25.02 ± 0.09 cm y 10.54 ± 0.07 cm, respectivamente, en Zovawk. Las mediciones morfométricas del cráneo y la anatomía aplicada de la región de la cabeza de Zovawk proporcionan datos de referencia importantes para futuras investigaciones en el campo de la anatomía aplicada.
Descritores: Cabeça/anatomia & histologia
-Crânio/anatomia & histologia
Suínos
Parâmetros de Referência
Índia
Bloqueio Nervoso
Limites: Animais
Responsável: CL1.1 - Biblioteca Central


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Id: biblio-1135540
Autor: Subbiya, Arunajatesan; Roopchander, Krishnamurthy; Mahalakshmi, Krishnan; Padmavathy, Kesavaram; Vivekanandan, Paramasivam.
Título: Bactericidal and Smear Layer Removal Efficacy of Herbal Alternatives Against Enterococcus Faecalis Dentinal Biofilm - An ex-vivo Study
Fonte: Pesqui. bras. odontopediatria clín. integr;20:e5475, 2020. tab, graf.
Idioma: en.
Resumo: Abstract Objective: To assess the antibacterial and smear layer removal ability of Trigonella foenum, Syzygium cumini, Terminalia chebula seed extracts against E. faecalis dentinal biofilm. Material and Methods: Agar well diffusion, micro broth dilution assay and time-kill curve assay were performed to determine the antibacterial activity. The ability of the herbal extracts to remove the smear layer on the root canal surface was assessed by scanning electron microscopy. Results: Antibacterial activity was observed for the extracts of S. cumini and T. chebula on E. faecalis dentinal biofilm and its planktonic counterparts. The smear layer was efficiently removed by the seed extracts of T. chebula alone. Seed extracts of T. foenum neither possessed antibacterial effect nor smear layer removal ability. Conclusion: The extracts of T. chebula seeds may replace conventional irrigant due to its antibacterial properties and smear layer removing the ability. The extracts of S. cumini may be used as an intracanal medicament as it exhibited a bactericidal effect against the E. faecalis dentinal biofilm following 18 hours of incubation.
Descritores: Microscopia Eletrônica de Varredura/instrumentação
Preparo de Canal Radicular/instrumentação
Syzygium/microbiologia
Preparações de Plantas/uso terapêutico
Endodontia
-Estatísticas não Paramétricas
Biofilmes
Ágar
Índia/epidemiologia
Antibacterianos
Tipo de Publ: Estudo de Avaliação
Responsável: BR1264.1 - Biblioteca Setorial Prof Alberto M Campos


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Id: biblio-1056885
Autor: Bhattacharya, Swastika; Purayil, Tina Puthen; Ginjupalli, Kishore; Kini, Sandya; Pai, Swathi.
Título: Effect of Thermocycling on the Colour Stability of Aesthetic Restorative Materials: An in-vitro Spectrophotometric Analysis
Fonte: Pesqui. bras. odontopediatria clín. integr;20:e5174, 2020. tab.
Idioma: en.
Resumo: Abstract Objective: To compare the color stability of Cention N, Fuji IX GP Extra, and Fuji IX GP after thermocycling. Material and Methods: Ten discs of each material of dimension 10 x 1 mm were prepared using a split mold. The preparations of the specimens were done according to the powder/liquid ratio as recommended by the manufacturers [4.6:1, 3.4:1 and 3.6:1 for the groups I, II, and III, respectively]. After setting, the samples were retrieved, and the thickness of each specimen was measured using a micrometer at five different locations. The specimens with variations in thickness, porosity or cracks were discarded and thus not included in the study. The selected specimens were stored in distilled water for 24 hours prior to testing. The prepared specimens were thermocycled at 5°C and 55°C, with a dwell time of 15 seconds for 250 or 500 cycles. Subsequently, the color parameters of the discs were measured using a spectrophotometer. The data were analyzed using two way ANOVA test, and a p-value <0.001 was considered. Results: Thermocycling resulted in changes in the color of both Glass Ionomer cement and Cention N (p<0.001). Among the materials tested, Cention N showed superior color stability. Conclusion: Cention N exhibited better color stability compared to Glass ionomer cements.
Descritores: Espectrofotometria/métodos
Materiais Dentários
Estética Dentária
Cimentos de Ionômeros de Vidro
-Análise de Variância
Índia
Tipo de Publ: Estudo Comparativo
Responsável: BR1264.1 - Biblioteca Setorial Prof Alberto M Campos



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