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Id: biblio-1131228
Autor: Askin, Lutfu; Tanrıverdi, Okan; Askin, Husna Sengul.
Título: O Efeito da Doença de Coronavírus 2019 nas Doenças Cardiovasculares / The Effect of Coronavirus Disease 2019 on Cardiovascular Diseases
Fonte: Arq. bras. cardiol;114(5):817-822, maio 2020. graf.
Idioma: pt.
Resumo: Resumo A doença de coronavírus 2019 (COVID-19) é uma pandemia global afetando o mundo, estando presente em mais de 1.300.000 pacientes. O COVID-19 age pelo receptor da enzima conversora de angiotensina 2 (ECA2). As comorbidades cardiovasculares são mais frequentes com COVID-19, e cerca 10% de casos desenvolvem miocardite (22% de pacientes críticas). Mais pesquisas serão necessárias para continuar ou descontinuar inibidores de ECA e bloqueadores dos receptores da angiotensina, que são essenciais para hipertensão e insuficiência cardíaca em COVID-19. Pesquisa intensiva é promissora para o tratamento e a prevenção da COVID-19.

Abstract Coronavirus disease 2019 (COVID-19) is a global pandemic affecting the world, seen in more than 1,300,000 patients. COVID-19 acts through the angiotensin-converting enzyme 2 (ACE2) receptor. Cardiovascular comorbidities are more common with COVID-19, and nearly 10% of cases develop myocarditis (22% of critical patients). Further research is needed to continue or discontinue ACE inhibitors and angiotensin receptor blockers, which are essential in hypertension and heart failure in COVID-19. Intensive research is promising for the treatment and prevention of COVID-19.
Descritores: Pneumonia Viral/epidemiologia
Doenças Cardiovasculares/epidemiologia
Infecções por Coronavirus/epidemiologia
Betacoronavirus
-Antivirais/uso terapêutico
Pneumonia Viral/enzimologia
Pneumonia Viral/mortalidade
Pneumonia Viral/tratamento farmacológico
Doenças Cardiovasculares/enzimologia
Doenças Cardiovasculares/mortalidade
Comorbidade
China/epidemiologia
Cloroquina/uso terapêutico
Infecções por Coronavirus
Infecções por Coronavirus/enzimologia
Infecções por Coronavirus/mortalidade
Infecções por Coronavirus/tratamento farmacológico
Peptidil Dipeptidase A/metabolismo
Antirreumáticos/uso terapêutico
Antagonistas de Receptores de Angiotensina/metabolismo
Pandemias
Hipertensão/enzimologia
Hipertensão/epidemiologia
Limites: Humanos
Animais
Tipo de Publ: Revisão
Responsável: BR1.1 - BIREME


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Id: biblio-1139019
Autor: Zhang, Meiyue; Real Cancio, Rosa María; Tamargo Barbeito, Teddy Osmin; León Castellón, Roberto.
Título: Sobrepeso y obesidad en la autopercepción corporal de adultos en China / Overweight and obesity in adult body self-perception in China
Fonte: Rev. cuba. med;58(3):e1168, jul.-set. 2019. tab.
Idioma: es.
Resumo: Introducción: En China la prevalencia del sobrepeso y obesidad está aumentando de manera vertiginosa. Objetivo: Valorar la autopercepción corporal de los adultos chinos y determinar su relación con los indicadores antropométricos. Métodos: Se realizó un estudio observacional de corte transversal en Panzhihua, China. La muestra estuvo conformada por n = 151 sujetos, con edades comprendidas entre los 18 y 80 años que cumplieron con los criterios de inclusión establecidos. Se les realizó cuestionario a través de una entrevista presencial y mediciones del peso, talla, circunferencia de la cintura y de la cadera, determinaciones del índice de masa corporal, índice de circunferencia de la cintura y la de cadera y el porcentaje de grasa corporal. Resultados: Según la clasificación del porcentaje de grasa corporal se determinó normopeso (10,6 por ciento), 28,5 por ciento con sobrepeso y 60,9 por ciento con obesidad. De acuerdo con el índice de masa corporal se encontró en el nivel delgado (5,3 por ciento), 47,0 por ciento normopeso, 32,5 por ciento en sobrepeso y 15,2 por ciento obesos. Según el índice de circunferencia de la cintura y la de cadera, 34,4 por ciento fue normal y 65,6 por ciento presentó obesidad abdominal. La autopercepción corporal: 54,7 por ciento de los sujetos se autopercibieron como normopeso, 24,3 por ciento tenían una percepción de sobrepeso y 12,2 por ciento se autopercibió obeso. Las correlaciones entre la autopercepción corporal, el índice de masa corporal y el porcentaje de grasa corporal expresaron diferencia significativa (p ;0,05), la autopercepción corporal y el índice de circunferencia de la cintura y la de cadera no evidenció diferencia (p> 0,05). Según la correlación de Pearson, el porcentaje de grasa corporal fue más confiable como indicador. Conclusión: La autopercepción corporal de los sujetos en esta investigación no fue adecuada. El porcentaje de grasa corporal fue el indicador antropométrico más confiable del estudio(AU)

Introduction: In China, the prevalence of overweight and obesity is increasing dramatically. Objective: To assess the body self-perception of Chinese adults and to determine their relationship with anthropometric indicators. Methods: An observational cross-sectional study was conducted in Panzhihua, China. The sample was made up of n = 151 subjects, aged between 18 and 80 years who met the established inclusion criteria. A questionnaire was conducted through a face-to-face interview and measurements of weight, height, waist and hip circumference, determinations of the body mass index, waist circumference index and that of the hip and the percentage of body fat. Results: According to the classification of the body fat percentage, it was determined 10.6 percent normal weight, 28.5 percent overweight and 60.9 percent obesity. According to the body mass index, it was found 5.3 percent in the thin level, 47.0 percent normal weight, 32.5 percent overweight and 15.2 percent obese. According to the waist and hip circumference index, 34.4 percent was normal and 65.6 percent had abdominal obesity. Regarding body self-perception, 54.7 percent of the subjects self-perceived as normal weight, 24.3 percent considered themselves to be overweight and 12.2 percent self-perceived as obese. The correlations between body self-perception, body mass index and body fat percentage expressed a significant difference (p;0.05), body self-perception and the waist and hip circumference index showed no difference (p;0.05). According to the Pearson correlation, the percentage of body fat was more reliable as an indicator. Conclusion: The body self-perception of the subjects in this research was not adequate. Body fat percentage was the most reliable anthropometric indicator in the study(AU)
Descritores: Autoimagem
Sobrepeso/epidemiologia
Obesidade/epidemiologia
-Estudos de Casos e Controles
China
Estudos Transversais
Grupo com Ancestrais do Continente Asiático/etnologia
Limites: Humanos
Masculino
Feminino
Tipo de Publ: Estudo Observacional
Responsável: CU1.1 - Biblioteca Médica Nacional


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Id: biblio-1146257
Autor: Pedrosa, Nathália Lima; Albuquerque, Nila Larisse Silva de.
Título: Série histórica da COVID-19 em diferentes países / Historical data series of COVID-19 in different countries / Serie de datos históricos de COVID-19 en diferentes países
Fonte: Rev. enferm. UERJ;28:e50470, jan.-dez. 2020.
Idioma: en; pt.
Resumo: Objetivo: analisar casos acumulados da COVID-19 em Brasil, Espanha, Itália, China e EUA. Métodos: estudo ecológico, com uso de dados secundários. Realizou-se série temporal de casos cumulativos de COVID-19 por 28 dias, após o 100º caso confirmado de cada país (baseado nas estatísticas do Worldometer 2020). Modelos de tendência linear, exponencial, potencial e logaritmo foram testados, sendo escolhido o melhor coeficiente de determinação (R²). No Brasil, a linha de tendência foi segmentada em 1º-14º dia e 15º-28º dia. Resultados: no 100º dia, os EUA possuíam maior número de casos e o Brasil, o menor. Houve linha de tendência em sua maioria exponencial, com maior velocidade de crescimento nos EUA. No Brasil, houve tendência de crescimento mais lento no segundo período. Conclusão: as linhas de tendência calculadas demonstraram pior prognóstico para os EUA. No Brasil, o crescimento do número cumulativo de casos foi mais lento na no segundo período do estudo.

Objective: to examine cumulative cases of COVID-19 in Brazil, Spain, Italy, China, and USA. Method: in this ecological study, secondary data were used to produce time series of cumulative cases of COVID-19 over 28 days after the 100th case confirmed in each country (from Worldometer 2020 statistics). Linear, exponential, potential and logarithmic trend models were tested, and the best coefficient of determination (R²) was chosen. In Brazil, the trend line was segmented into days 1-14 and 15-28. Results: on day 100, the USA had the highest number of cases and Brazil, the lowest. The trend lines were mostly exponential, with highest growth rate in the USA. In Brazil, the growth trend was slower in the second period. Conclusion: the calculated trend lines showed a worse prognosis for the USA. In Brazil, the cumulative number of cases grew more slowly in the second period of the study.

Objetivo: examinar casos acumulados de COVID-19 en Brasil, España, Italia, China y Estados Unidos. Método: en este estudio ecológico, se utilizaron datos secundarios para producir series de tiempo de casos acumulados de COVID-19 durante 28 días después del 100o caso confirmado en cada país (de las estadísticas del Worldometer 2020). Se probaron modelos de tendencia lineal, exponencial, potencial y logarítmica y se eligió el mejor coeficiente de determinación (R²). En Brasil, la línea de tendencia se segmentó en los días 1-14 y 15-28. Resultados: el día 100, EE.UU. tuvo el mayor número de casos y Brasil, el menor. Las líneas de tendencia fueron en su mayoría exponenciales, con la tasa de crecimiento más alta en los EE. UU. En Brasil, la tendencia de crecimiento fue más lenta en el segundo período. Conclusión: las líneas de tendencia calculadas mostraron un peor pronóstico para EE. UU. En Brasil, el número acumulado de casos creció más lentamente en el segundo período del estudio.
Descritores: Infecções por Coronavirus/epidemiologia
Betacoronavirus
-Espanha/epidemiologia
Estados Unidos/epidemiologia
Brasil/epidemiologia
China/epidemiologia
Estudos de Séries Temporais
Estudos Ecológicos
Itália/epidemiologia
Limites: Humanos
Responsável: BR1366.1 - Biblioteca Biomédica B - CB/B (Odontologia e Enfermagem)


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Id: biblio-1131510
Autor: Wei, D; Zhao, Y; Jia, Y; Hao, X; Situ, J; Yu, W; Huang, F; Jiang, H.
Título: Hepatitis E virus infection in buffaloes in South China / [Hepatite E infecção viral em búfalos no Sul da China]
Fonte: Arq. bras. med. vet. zootec. (Online);72(4):1122-1126, July-Aug. 2020. graf, ilus.
Idioma: en.
Projeto: National Natural Science Foundation of China; . Natural Science Foundation of Yunnan province; . Fundamental Research Funds for the Central Universities; . PUMC Youth Fund; . Training project of Kunming University of Science and Technology.
Resumo: Hepatitis E virus (HEV) infection is an important global public health issue. HEV infections are recognized as a zoonotic disease. Swine are believed to be the main reservoir of HEV. Recently, yaks, cows, and yellow cattle have been reported as new reservoirs of HEV. However, whether other species of cattle and buffaloes are sensitive to HEV infection is unknown. To investigate the prevalence of HEV infection in buffaloes, enzyme-linked immunosorbent assay (ELISA) and reverse transcription-nested polymerase chain reaction (RT-nPCR) were performed. Only one buffalo was positive to anti-HEV IgM antibody (1/106, 0.94%), and none were positive for anti-HEV IgG antibody. To our surprise, five serum (5/106, 4.72%) and three milk samples (3/40, 7.50%) from buffaloes were positive to HEV RNA. All strains of HEV isolated from buffaloes belong to genotype 4. Results indicate that buffaloes may be a new reservoir of HEV.(AU)

Infecção com o vírus Hepatite E (HEV) é uma importante questão de saúde pública global. Infecções HEV são reconhecidas como doença zoológica. Acredita-se que suínos são o principal reservatório de HEV. Recentemente iaques, vacas, e gado amarelo foram reportados como novos reservatórios do HEV. Porém, não se sabe se outras espécies de gado e búfalo são sensíveis a infecção HEV. Para investigar a prevalência de infecção HEV em búfalos, foram realizados prova de imunoabsorção enzimática e polimerização em cadeia inversa ancorada em transcrição. Apenas um búfalo foi positivo para o anticorpo anti-HEV IgM (1/106, 0,94%), e nenhum foi positivo para o anticorpo anti-HEV IgG. Para nossa surpresa cinco (5/106, 4,72%) e três amostras de leite (3/40, 7,50%) de búfalos foram positivos para HEV RNA. Todas as estirpes de HEV isoladas de búfalos pertencem ao genótipo 4. Resultados indicam que búfalos podem ser um reservatório de HEV.(AU)
Descritores: Búfalos
Vírus da Hepatite E
Hepatite E
-Zoonoses
China
Limites: Animais
Responsável: BR68.1 - Biblioteca Virginie Buff D'Ápice


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Id: biblio-1125343
Autor: Rodrigues, Paulo Henrique de Almeida; Gerzson, Lusiana Chagas.
Título: A dimensão geopolítica da pandemia de coronavírus / The geopolitical dimension of the pandemic coronavirus
Fonte: Physis (Rio J.);30(2):e300209, 2020.
Idioma: pt.
Descritores: Política
Infecções por Coronavirus/economia
Infecções por Coronavirus/história
Infecções por Coronavirus/epidemiologia
Estado
Betacoronavirus
-Estados Unidos
Brasil
China
Tipo de Publ: Comentário
Responsável: BR433.1 - CB/C - Biblioteca Biomédica C


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Id: biblio-968926
Autor: Yang, Fei; Zhang, Aihong; Li, Xiwang; Huo, Liangzhan; Di, Dianping; Miao, Hongqin.
Título: Occurrence and alternation of cytorhabdoviruses on wheat in northern China / Ocorrência e alternância de cytorhabdovirus em trigo no norte da China
Fonte: Biosci. j. (Online);34(6):1472-1476, nov.-dec. 2018.
Idioma: en.
Resumo: Northern cereal mosaic cytorhabdovirus (NCMV) and Barley yellow striate mosaic cytorhabdovirus (BYSMV) are two of the most important viral pathogens of wheat. Northern China is the main wheatproducing region in the country. Wheat growing regions pertaining to four provinces, located in northern China, were surveyed for occurrence of NCMV and BYSMV during the growing seasons of the years 2010 and 2016. Wheat leaf samples were collected randomly from symptomatic plants displaying stunting, chlorotic stripes or mosaic. Roughly 73 samples were collected in the year 2010 from 13 fields, and 154 samples were collected in 2016 from 41 fields. Samples were tested for the presence of NCMV or BYSMV using multiplex reverse transcription-polymerase chain reaction (mRTPCR). The results suggested that BYSMV (49.32% in 2010, 82.47% in 2016) is gradually replacing NCMV (87.67% in 2010, 13.64% in 2016) and becoming the main cytorhabdovirus in different wheat growing regions in northern China.

O cytorhabdovirus do mosaico do cereal do norte (NCMV) e o cytorhabdovirus do mosaico estriado amarelo da cevada (BYSMV) são dois dos mais importantes patógenos virais do trigo. O norte da China é a principal região produtora de trigo do país. As regiões produtoras de trigo pertencentes a quatro províncias do norte da China foram pesquisadas quanto à ocorrência de NCMV e BYSMV durante as safras dos anos de 2010 e 2016. Amostras de folhas de trigo foram coletadas aleatoriamente de plantas sintomáticas, exibindo listras ou mosaico clorótico com baixo crescimento. Cerca de 73 amostras foram coletadas no ano de 2010 a partir de 13 campos, e 154 amostras foram coletadas em 2016 de 41 campos. As amostras foram testadas quanto à presença de NCMV ou BYSMV usando reação em cadeia da polimerase de transcrição reversa multiplex (mRT-PCR). Os resultados sugerem que o BYSMV (49,32% em 2010, 82,47% em 2016) está gradualmente substituindo o NCMV (87,67% em 2010, 13,64% em 2016) e se tornando o principal cytorhabdovirus em diferentes regiões produtoras de trigo no norte da China.
Descritores: Triticum
China
Inquéritos e Questionários
Reação em Cadeia da Polimerase Via Transcriptase Reversa
Responsável: BR396.1 - Biblioteca Central


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Id: lil-780801
Autor: Zhao, Youyun; Wu, Jianhua; Sun, Lijun; Liu, Guangzhong; Li, Bo; Zheng, Yi; Li, Xiaodong; Tao, Junxiu.
Título: Prevalence of mutations in HBV DNA polymerase gene associated with nucleos(t)ide resistance in treatment-naive patients with Chronic Hepatitis B in Central China
Fonte: Braz. j. infect. dis;20(2):173-178, Mar.-Apr. 2016. tab.
Idioma: en.
Resumo: Abstract Objective There are a lot of disagreements in the studies on hepatitis B virus (HBV) DNA polymerase mutation rate associated with nucleos(t)ide analogues (NAs) in treatment-naive chronic hepatitis B (CHB) patients. This is the first study aimed to investigate the prevalence of spontaneous HBV resistance mutations in Central China. Methods This study included treatment-naive patients with CHB from June 2012 to May 2015 receiving care at the Institute of Liver Disease in Central China. All patients completed a questionnaire covering different aspects, such as family medical history, course of liver disease, medication history, alcohol use, among others. Mutations in HBV DNA polymerase associated with NAs resistance were detected using INNO-LiPA assay. Results 269 patients were infected with HBV genotype B (81.4%), C (17.9%), and both B and C (0.7%). Mutations in HBV DNA polymerase were detected in 24 patients (8.9%) including rtM204I/V (n = 6), rtN236T (n = 5), rtM250V (n = 2), rtL180M (n = 2), rtT184G (n = 1), rtM207I (n = 1), rtS202I (n = 1), rtM204V/I & rtL180M (n = 5), and rtM204I & rtM250V (n = 1). Conclusion Spontaneous HBV resistance mutations in HBV DNA polymerase were found in treatment-naive patients with CHB in Central China. These findings suggest that we should analyze HBV DNA polymerase resistance mutation associated with NAs before giving antiviral therapy such as lamivudine (LAM), adefovir (ADV), and telbivudine (LdT).
Descritores: DNA Viral/genética
Vírus da Hepatite B/genética
Hepatite B Crônica/virologia
Farmacorresistência Viral/genética
DNA Polimerase Dirigida por DNA/genética
Mutação/genética
-Antivirais/uso terapêutico
China
Vírus da Hepatite B/efeitos dos fármacos
Prevalência
Estudos Prospectivos
Hepatite B Crônica/tratamento farmacológico
Genótipo
Limites: Humanos
Masculino
Feminino
Gravidez
Adulto
Pessoa de Meia-Idade
Idoso
Adulto Jovem
Tipo de Publ: Research Support, Non-U.S. Gov't
Responsável: BR1.1 - BIREME


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Id: lil-780807
Autor: Sun, Huiquan; Sun, Qiufeng; Jiang, Wunjun; Chen, Zhengrong; Huang, Li; Wang, Meijuan; Ji, Wei; Shao, Xuejun; Yan, Yongdong.
Título: Prevalence of rhinovirus in wheezing children: a comparison with respiratory syncytial virus wheezing
Fonte: Braz. j. infect. dis;20(2):179-183, Mar.-Apr. 2016. tab, graf.
Idioma: en.
Resumo: Abstract Objective To explore the distribution and clinical manifestations of rhinovirus infection in wheezing children, and compare the clinical differences between rhinovirus- and respiratory syncytial virus-induced wheezing. Materials and methods This prospective cohort study was carried out in Children's Hospital of Soochow University from Dec 2012 to Nov 2014. We enrolled consecutive hospitalized children <60 months of age presented with wheezing. Clinical data including cough, fever, dyspnea, crackles were recorded by pediatricians on the first day of admission. Meanwhile, nasopharyngeal aspirates were obtained to test for respiratory viruses, by using polymerase chain reaction method for rhinovirus, human bocavirus, and human metapneumovirus, and direct immunofluorescence assay to test for respiratory syncytial virus, adenovirus, parainfluenza virus types 1–3, and influenza virus types A and B. Results Rhinovirus was a main causative agent isolated in 14.7% of the hospitalized wheezing children in Suzhou, China, being second to respiratory syncytial virus (21.0%). Different from respiratory syncytial virus infection, which peaked in winter months, rhinovirus could be detected all year round, peaked between July and September, and in November. Children with rhinovirus infection were older and presented with more often allergic sensitizations, blood eosinophilia, and leukocytosis than those of respiratory syncytial virus infection. Logistic regression analysis revealed that rhinovirus-infected children experienced earlier wheezing more often than respiratory syncytial virus children (odds ratio, 3.441; 95% confidence interval, 1.187–9.979; p = 0.023). Conclusion Rhinovirus was a main viral pathogen in wheezing children, especially in summer time. Rhinovirus-induced wheezing was different from respiratory syncytial virus, apart from seasonal epidemics; these two groups differed with regard to age, allergic sensitizations, laboratory test, and history of wheezing episodes.
Descritores: Rhinovirus/isolamento & purificação
Sons Respiratórios/etiologia
Infecções por Vírus Respiratório Sincicial/epidemiologia
Infecções por Picornaviridae/epidemiologia
-Estações do Ano
China/epidemiologia
Prevalência
Estudos Prospectivos
Estudos de Coortes
Infecções por Vírus Respiratório Sincicial/virologia
Infecções por Picornaviridae/virologia
Limites: Humanos
Masculino
Feminino
Lactente
Pré-Escolar
Tipo de Publ: Estudo Comparativo
Responsável: BR1.1 - BIREME


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Id: biblio-828116
Autor: Huang, Feng; Lu, Lianghua; Jiang, Wujun; Yan, Yongdong; Ji, Wei; Yang, Bin; Yu, Shenglin.
Título: The epidemiology and clinical features of Mycoplasma pneumoniae infection in neonates
Fonte: Braz. j. infect. dis;20(4):374-378, July-Aug. 2016. tab, graf.
Idioma: en.
Projeto: Science and Technology Program of Suzhou; . Science and Technology Projects for the Youth of Suzhou; . Science and Technology Program of Suzhou Health Bureau.
Resumo: Abstract Objectives This retrospective study was aimed to explore the epidemiological and clinical profiles of Mycoplasma pneumoniae infection in neonates. Methods From 2011 to 2014, 1322 hospitalized neonates with lower respiratory tract infections were screened for Mycoplasma pneumoniae by detection of Mycoplasma pneumoniae antibodies using Serion ELISA classic Mycoplasma pneumoniae kits. Results Mycoplasma pneumoniae was identified in 89 (6.7%) patients. The age ranged from 1 day to 28 days with a median of 22 days. The male to female ratio was 1.15:1. Mycoplasma pneumoniae infection peaked in spring (from March through May) and winter (from December through February). Compared with non-Mycoplasma pneumoniae infected neonates, those with Mycoplasma pneumoniae infection were older, presented fever more frequently, and had less tachypnea. Conclusions Mycoplasma pneumoniae could be an important etiologic agent for respiratory tract infection in neonates. In neonates Mycoplasma pneumoniae infection was usually associated with older age, presence of fever, and less tachypnea. Mycoplasma pneumoniae infection in neonates tends to be a mild process.
Descritores: Infecções Respiratórias/microbiologia
Infecções por Mycoplasma/epidemiologia
Mycoplasma pneumoniae/imunologia
-Infecções Respiratórias/diagnóstico
Infecções Respiratórias/epidemiologia
Estações do Ano
Imunoglobulina G/sangue
Imunoglobulina M/sangue
Ensaio de Imunoadsorção Enzimática
China/epidemiologia
Estudos Retrospectivos
Anticorpos Antibacterianos/sangue
Infecções por Mycoplasma/diagnóstico
Limites: Humanos
Masculino
Feminino
Recém-Nascido
Responsável: BR1.1 - BIREME


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Id: biblio-828134
Autor: Mu, Xia; Xu, Yan; Yang, Tingxiu; Zhang, Ji; Wang, Chong; Liu, Wei; Chen, Jing; Tang, Luyu; Yang, Huai.
Título: Improving hand hygiene compliance among healthcare workers: an intervention study in a Hospital in Guizhou Province, China
Fonte: Braz. j. infect. dis;20(5):413-418, Sept.-Oct. 2016. tab, graf.
Idioma: en.
Projeto: Science Foundation of Guizhou Province of China.
Resumo: Abstract Objective Hand hygiene (HH) is a critical component for controlling hospital-acquired infection (HAI). The present study was designed to develop an intervention approach to improve compliance with HH among healthcare workers in a hospital setting. Methods The HH intervention study was conducted in Guizhou Provincial People's Hospital, Guiyang, China and organized by its Department of HAI Management. It was an observational, prospective, quasiexperimental (before-after intervention) study. The study was divided into two phases: the baseline phase and the intervention phase. The investigative team included clinical monitoring staff and infection control practitioners who received a series of instructions on HH compliance, monitoring skills, and measurement of the use of HH products. Results Based on 27,852 observations in a 17-month period, the rate of compliance with HH improved from 37.78% at baseline to 75.90% after intervention. Significant improvement in compliance and an increase in consumption of HH products was observed after intervention. The per patient-day consumption of alcohol-based hand rub products and handwash agents increased by 4.75 mL and 4.55 mL, respectively. The consumption of paper towels increased 3.41 sheets per patient-day. During the same period, the prevalence rate of HAI decreased 0.83%. Conclusions This study demonstrates that a significant improvement in compliance with HH can be achieved through a systemic, multidimensional intervention approach involving all categories of healthcare workers in a hospital setting, which may result in a decrease of the HAI rate.
Descritores: Recursos Humanos em Hospital/educação
Controle de Infecções/métodos
Transmissão de Doença Infecciosa do Profissional para o Paciente/prevenção & controle
Fidelidade a Diretrizes/estatística & dados numéricos
Higiene das Mãos/métodos
-Fatores de Tempo
Avaliação de Programas e Projetos de Saúde
China
Estudos Prospectivos
Hospitais
Limites: Humanos
Tipo de Publ: Estudo Observacional
Responsável: BR1.1 - BIREME



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BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde