Base de dados : LILACS
Pesquisa : Z01.542.101 [Categoria DeCS]
Referências encontradas : 3 [refinar]
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Id: biblio-1104063
Autor: Trendafilova, Antoaneta; Kutova, Nikolina; Ozek, Gulmira; Todorova, Milka; Yur, Suleyman; Ozek, Temel; Dimitrov, Dimitar.
Título: Phenolic profile and antioxidant, acetylcholinesterase, and tyrosinase inhibitor activities of Jurinea tzar-ferdinandii Davidov, an endemic plant of the Balkans / Perfil fenólico y actividad antioxidante, acetilcolinesterasa e inhibidora de tirosinasa de Jurinea tzar-ferdinandii Davidov, planta endémica de los Balcanes
Fonte: Bol. latinoam. Caribe plantas med. aromát;19(2):161-166, mar. 2020. tab, ilus.
Idioma: en.
Projeto: Bulgarian Academy of Sciences; . TUBITAK.
Resumo: The methanol extract of the Balkan endemic species Jurinea tzar-ferdinandii Davidov demonstrated weak antioxidant activity against DPPH• and ABTS+• and low inhibitory potential against acetylcholinesterase (8.3% Inh.) and tyrosinase (IC50 = 208 ± 8 µg/mL) enzymes. Phytochemical investigation of the extract led to isolation and identification of apigenin, luteolin, apigenin-7-O-glucoside, apigenin-4'-O-glucoside, apigenin-7-O-gentiobioside, luteolin-4'-O-glucoside, rutin, narcissin, chlorogenic and 1,5-dicaffeoylquinic acid. With exception of apigenin and rutin, all isolated compounds are reported for the first time in the representatives of genus Jurinea. The distribution of flavonoids was discussed from chemotaxonomic point of view.

El extracto de metanol de la especie endémica de los Balcanes Jurinea tzar-ferdinandii Davidov demostró una actividad antioxidante débil contra DPPH• y ABTS+• y un bajo potencial inhibidor contra las enzimas acetilcolinesterasa (8.3% Inh.) tirosinasa (IC50 = 208 ± 8 µg/mL). La investigación fitoquímica del extracto condujo al aislamiento e identificación de apigenina, luteolina, apigenina-7-Oglucósido, apigenina-4'-O-glucósido, apigenina-7-O-gentiobiósido, luteolina-4'-O-glucósido, rutina, narcissin, clorogénico y ácido 1,5- dicafeoilquinico. Con excepción de la apigenina y la rutina, todos los compuestos aislados se informan por primera vez en el género Jurinea. La distribución de flavonoides se discute desde el punto de vista quimiotaxonómico.
Descritores: Asteraceae/química
Antioxidantes/farmacologia
Antioxidantes/química
-Fenóis/análise
Flavonoides/análise
Inibidores da Colinesterase
Monofenol Mono-Oxigenase/antagonistas & inibidores
Metanol
Península Balcânica
Responsável: CL1.1 - Biblioteca Central


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Id: biblio-1007815
Autor: Aneva, Ina; Trendafilova, Antoaneta; Nikolova, Milena; Todorova, Milka; Georgieva, Kristina.
Título: Essential oil composition of the Balkan endemic Thymus longedentatus (Degen & Urum. ) Ronniger / Composición del aceite esencial de Thymus longedentatus (Degen & Urum. ) Ronniger endemic de los Balcanes
Fonte: Bol. latinoam. Caribe plantas med. aromát;18(2):197-203, mar. 2019. tab, mapas.
Idioma: en.
Resumo: The chemical composition of essential oil obtained from the aerial parts of the Balkan endemic species Thymus longedentatus was studied by GC-MS. Twenty eight compounds, consisting 98.2% of the total components were detected in amounts exceeding 0.1%. The oil was characterized by relatively high concencentration of oxygentated monoterpenes (78.7%), among which citral isomers neral (27.5%) and geranial (30.3%) were the principal ones. In addition, 1,8-cineole (7.8%), trans-ß-ocimene (7.5%), and ß-myrcene (3.7%) were detected in significant ammounts. Germacrene D (4.4%) was found to be the main sesquiterpene in the essential oil.

Se estudió mediante GC-MS la composición química del aceite esencial obtenido de las partes aéreas de Thymus longedentatus, especie endémica de los Balcanes. Se detectaron veintiocho compuestos, que representaban un 98,2% del total de compuestos y que se encontraban en cantidades superiores al 0,1%. El aceite se caracterizó por una concentración relativamente alta de monoterpenos oxigenados (78.7%), entre los cuales los isómeros de citral, neral (27.5%) y geranial (30.3%) eran los principales. Además, se detectó 1,8-cineol (7,8%), trans-ß-ocimeno (7,5%) y ß-mirceno (3,7%) en cantidades significativas. Se encontró que Germacreno D (4.4%) es el principal sesquiterpeno en el aceite esencial.
Descritores: Plantas Medicinais/química
Óleos Voláteis/química
Thymus (Planta)/química
-Terpenos/análise
Óleos Voláteis/isolamento & purificação
Península Balcânica
Cromatografia Gasosa-Espectrometria de Massas
Responsável: CL1.1 - Biblioteca Central


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Id: lil-748360
Autor: Feitosa, Esaú Samuel; Sampaio, Vanderson; Sachett, Jaqueline; Castro, Daniel Barros de; Noronha, Maria das Dores Nogueira; Lozano, Jorge Luis López; Muniz, Emiro; Ferreira, Luiz Carlos de Lima; Lacerda, Marcus Vinícius Guimarães de; Monteiro, Wuelton Marcelo.
Título: Snakebites as a largely neglected problem in the Brazilian Amazon: highlights of the epidemiological trends in the State of Amazonas
Fonte: Rev. Soc. Bras. Med. Trop;48(supl.1):34-41, 2015. tab, graf.
Idioma: en.
Resumo: Envenoming snakebites are thought to be a particularly important threat to public health worldwide, especially in rural areas of tropical and subtropical countries. The true magnitude of the public health threat posed by snakebites is unknown, making it difficult for public health officials to optimize prevention and treatment. The objective of this work was to conduct a systematic review of the literature to gather data on snakebite epidemiology in the Amazon region and describe a case series of snakebites from epidemiological surveillance in the State of Amazonas (1974-2012). Only 11 articles regarding snakebites were found. In the State of Amazonas, information regarding incidents involving snakes is scarce. Historical trends show an increasing number of cases after the second half of the 1980s. Snakebites predominated among adults (20-39 years old; 38%), in the male gender (78.9%) and in those living in rural areas (85.6%). The predominant snake envenomation type was bothropic. The incidence reported by the epidemiological surveillance in the State of Amazonas, reaching up to 200 cases/100,000 inhabitants in some areas, is among the highest annual snakebite incidence rates of any region in the world. The majority of the cases were reported in the rainy season with a case-fatality rate of 0.6%. Snakebite envenomation is a great disease burden in the State of Amazonas, representing a challenge for future investigations, including approaches to estimating incidence under-notification and case-fatality rates as well as the factors related to severity and disabilities.
Descritores: DNA Mitocondrial/genética
Cervos/classificação
Cervos/genética
Repetições de Microssatélites/genética
-Península Balcânica
Biodiversidade
Conservação dos Recursos Naturais
Frequência do Gene
Variação Genética
Genética Populacional
Variação Estrutural do Genoma
Grécia
Filogeografia
Análise de Sequência de DNA
Translocação Genética
Limites: Animais
Tipo de Publ: Research Support, Non-U.S. Gov't
Responsável: BR1.1 - BIREME



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