Base de datos : MEDLINE
Búsqueda : B04.280.120.400 [Categoria DeCS]
Referencias encontradas : 22 [refinar]
Mostrando: 1 .. 10   en el formato [Largo]

página 1 de 3 va a la página          

  1 / 22 MEDLINE  
              next record last record
selecciona
para imprimir
Fotocopia
Texto completo
PMID:28155197
Autor:Rosario K; Breitbart M; Harrach B; Segalés J; Delwart E; Biagini P; Varsani A
Dirección:College of Marine Science, University of South Florida, Saint Petersburg, FL, 33701, USA. krosari2@mail.usf.edu.
Título:Revisiting the taxonomy of the family Circoviridae: establishment of the genus Cyclovirus and removal of the genus Gyrovirus.
Fuente:Arch Virol; 162(5):1447-1463, 2017 May.
ISSN:1432-8798
País de publicación:Austria
Idioma:eng
Resumen:The family Circoviridae contains viruses with covalently closed, circular, single-stranded DNA (ssDNA) genomes, including the smallest known autonomously replicating, capsid-encoding animal pathogens. Members of this family are known to cause fatal diseases in birds and pigs and have been historically classified in one of two genera: Circovirus, which contains avian and porcine pathogens, and Gyrovirus, which includes a single species (Chicken anemia virus). However, over the course of the past six years, viral metagenomic approaches as well as degenerate PCR detection in unconventional hosts and environmental samples have elucidated a broader host range, including fish, a diversity of mammals, and invertebrates, for members of the family Circoviridae. Notably, these methods have uncovered a distinct group of viruses that are closely related to members of the genus Circovirus and comprise a new genus, Cyclovirus. The discovery of new viruses and a re-evaluation of genomic features that characterize members of the Circoviridae prompted a revision of the classification criteria used for this family of animal viruses. Here we provide details on an updated Circoviridae taxonomy ratified by the International Committee on the Taxonomy of Viruses in 2016, which establishes the genus Cyclovirus and reassigns the genus Gyrovirus to the family Anelloviridae, a separate lineage of animal viruses that also contains circular ssDNA genomes. In addition, we provide a new species demarcation threshold of 80% genome-wide pairwise identity for members of the family Circoviridae, based on pairwise identity distribution analysis, and list guidelines to distinguish between members of this family and other eukaryotic viruses with circular, ssDNA genomes.
Tipo de publicación:JOURNAL ARTICLE
Nombre de substancia:0 (DNA, Viral)


  2 / 22 MEDLINE  
              first record previous record next record last record
selecciona
para imprimir
Fotocopia
Texto completo
PMID:27780970
Autor:Yao S; Tuo T; Gao X; Han C; Li Y; Gao Y; Zhang Y; Liu C; Qi X; Gao H; Wang Y; Wang X
Dirección:Division of Avian Infectious Diseases, State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin 150069, China.
Título:Avian gyrovirus 2 in poultry, China, 2015-2016.
Fuente:Emerg Microbes Infect; 5(10):e112, 2016 Oct 26.
ISSN:2222-1751
País de publicación:United States
Idioma:eng
Tipo de publicación:LETTER


  3 / 22 MEDLINE  
              first record previous record next record last record
selecciona
para imprimir
Fotocopia
PubMed Central Texto completo
Texto completo
PMID:26196944
Autor:Ye J; Tian X; Xie Q; Zhang Y; Sheng Y; Zhang Z; Wang C; Zhu H; Wang Y; Shao H; Qin A
Título:Avian Gyrovirus 2 DNA in Fowl from Live Poultry Markets and in Healthy Humans, China.
Fuente:Emerg Infect Dis; 21(8):1486-8, 2015 Aug.
ISSN:1080-6059
País de publicación:United States
Idioma:eng
Tipo de publicación:LETTER; RESEARCH SUPPORT, NON-U.S. GOV'T


  4 / 22 MEDLINE  
              first record previous record next record last record
selecciona
para imprimir
Fotocopia
PubMed Central Texto completo
Texto completo
PMID:26036564
Autor:Li L; Pesavento PA; Gaynor AM; Duerr RS; Phan TG; Zhang W; Deng X; Delwart E
Dirección:Blood Systems Research Institute, 270 Masonic Ave., San Francisco, CA, 94118, USA.
Título:A gyrovirus infecting a sea bird.
Fuente:Arch Virol; 160(8):2105-9, 2015 Aug.
ISSN:1432-8798
País de publicación:Austria
Idioma:eng
Resumen:We characterized the genome of a highly divergent gyrovirus (GyV8) in the spleen and uropygial gland tissues of a diseased northern fulmar (Fulmarus glacialis), a pelagic bird beached in San Francisco, California. No other exogenous viral sequences could be identified using viral metagenomics. The small circular DNA genome shared no significant nucleotide sequence identity, and only 38-42 % amino acid sequence identity in VP1, with any of the previously identified gyroviruses. GyV8 is the first member of the third major phylogenetic clade of this viral genus and the first gyrovirus detected in an avian species other than chicken.
Tipo de publicación:JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL


  5 / 22 MEDLINE  
              first record previous record next record last record
selecciona
para imprimir
Fotocopia
PubMed Central Texto completo
Texto completo
PMID:26013257
Autor:Phan TG; da Costa AC; Zhang W; Pothier P; Ambert-Balay K; Deng X; Delwart E
Dirección:Blood Systems Research Institute, San Francisco, CA, 94118, USA.
Título:A new gyrovirus in human feces.
Fuente:Virus Genes; 51(1):132-5, 2015 Aug.
ISSN:1572-994X
País de publicación:United States
Idioma:eng
Resumen:A novel gyrovirus genome found in the feces of an adult with diarrhea is described. The genome shows the three expected main ORFs encoding a structural protein (VP1), nonstructural protein (VP2), and Apoptin protein (VP3), which shared identities of 41, 42, and 38 % with those of the most closely related gyrovirus proteins, respectively. Given the high divergence in its genome, this gyrovirus may be considered the prototype for a new viral species (GyV9) in the Gyrovirus genus. Because the closest relatives of this gyrovirus infect chicken, a possible dietary origin for the presence of this virus in human feces is discussed.
Tipo de publicación:JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL; RESEARCH SUPPORT, NON-U.S. GOV'T
Nombre de substancia:0 (DNA, Viral)


  6 / 22 MEDLINE  
              first record previous record next record last record
selecciona
para imprimir
Fotocopia
Texto completo
PMID:25890989
Autor:Prasetyo AA; Desyardi MN; Tanamas J; Suradi; Reviono; Harsini; Kageyama S; Chikumi H; Shimizu E
Dirección:Department of Microbiology, Faculty of Medicine, Sebelas Maret University, Jl. Ir. Sutami No. 36A, Surakarta 57126 (Indonesia). afie.agp.la @ gmail.com
Título:Respiratory viruses and torque teno virus in adults with acute respiratory infections.
Fuente:Intervirology; 58(1):57-68, 2015.
ISSN:1423-0100
País de publicación:Switzerland
Idioma:eng
Resumen:OBJECTIVE: To define the molecular epidemiology of respiratory viral infections in adult patients. METHODS: Nasal and throat swabs were collected from all adult patients with influenza-like illness (ILI), acute respiratory infection (ARI), or severe ARI (SARI) admitted to a tertiary hospital in Surakarta, Indonesia, between March 2010 and April 2011 and analyzed for 19 respiratory viruses and for torque teno virus (TTV) and human gyrovirus (HGyV). RESULTS: Respiratory viruses were detected in 61.3% of the subjects, most of whom had ARI (90.8%, OR = 11.39), were hospitalized (96.9%, OR = 22.31), had asthma exacerbation (90.9%, OR = 8.67), and/or had pneumonia (80%, OR = 4.0). Human rhinovirus (HRV) A43 predominated. Influenza A H3N2, human metapneumovirus (HMPV) subtypes A1 and A2, the influenza B virus, human adenovirus B, and human coronavirus OC43 were also detected. All respiratory viruses were detected in the transition month between the rainy and dry seasons. No mixed respiratory virus infection was found. Coinfections of the influenza A H3N2 virus with TTV, HMPV with TTV, HRV with TTV, and human parainfluenza virus-3 with TTV were found in 4.7, 2.8, 19.8, and 0.9% of the samples, respectively. CONCLUSIONS: This study highlights the need to perform routine detection of respiratory viruses in adults hospitalized with ARI, asthma exacerbation, and/or pneumonia.
Tipo de publicación:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T


  7 / 22 MEDLINE  
              first record previous record next record last record
selecciona
para imprimir
Fotocopia
Texto completo
PMID:25319533
Autor:Fehér E; Pazár P; Lengyel G; Phan TG; Bányai K
Dirección:Institute for Veterinary Medical Research, Centre for Agricultural Research, Hungarian Academy of Sciences, Hungária krt. 21, Budapest, 1143, Hungary, feher.eniko@agrar.mta.hu.
Título:Sequence and phylogenetic analysis identifies a putative novel gyrovirus 3 genotype in ferret feces.
Fuente:Virus Genes; 50(1):137-41, 2015 Feb.
ISSN:1572-994X
País de publicación:United States
Idioma:eng
Resumen:The genomic sequence of a novel gyrovirus (GyV) 3 strain was detected from the fecal sample of a pet ferret. The length (2,359 nt) and the basic genomic structure of this strain was very similar to that of the single known GyV3 reference strain, whereas the genome sequence identity between the two strains was only 76 %. Similarly, moderate sequence homology was found within the predicted protein coding regions, VP1 (nt, 72 %; aa, 76 %), VP2 (nt, 84 %; aa, 85 %), and VP3 (nt, 85 %; aa, 73 %). Sequence identities were lower when comparing our strain with other GyV species (48-65 % genome-wide nt identity). Phylogenetic analysis of the coding regions clustered the ferret origin GyV3 strain within Clade A. Although the available whole genomic sequence of novel GyVs permits limited conclusions to be drawn regarding the classification of the Hungarian GyV3 strain, our data indicate that this novel strain may be considered as a new genotype within GyV3. Further investigations are needed to reveal the genetic diversity and biological properties of newly described members of the Gyrovirus genus.
Tipo de publicación:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
Nombre de substancia:0 (DNA, Viral); 0 (Viral Proteins)


  8 / 22 MEDLINE  
              first record previous record next record last record
selecciona
para imprimir
Fotocopia
Roehe, Paulo Michel
Texto completo
PMID:25439092
Autor:Varela AP; Dos Santos HF; Cibulski SP; Scheffer CM; Schmidt C; Sales Lima FE; Silva AD; Esteves PA; Franco AC; Roehe PM
Dirección:FEPAGRO - Saúde Animal, Instituto de Pesquisas Veterinárias Desidério Finamor (IPVDF), Estrada do Conde 6000, Eldorado do Sul CEP 92990-000, Rio Grande do Sul, Brazil; Laboratório de Virologia, Departamento de Microbiologia, Imunologia e Parasitologia, Instituto de Ciências Básicas da Saúde, UFRGS.
Título:Chicken anemia virus and avian gyrovirus 2 as contaminants in poultry vaccines.
Fuente:Biologicals; 42(6):346-50, 2014 Nov.
ISSN:1095-8320
País de publicación:England
Idioma:eng
Resumen:This study focuses on the detection of chicken anemia virus (CAV) and avian gyrovirus 2 (AGV2) genomes in commercially available poultry vaccines. A duplex quantitative real-time PCR (dqPCR), capable of identifying genomes of both viruses in a single assay, was employed to determine the viral loads of these agents in commercially available vaccines. Thirty five vaccines from eight manufacturers (32 prepared with live and 3 with inactivated microorganisms) were examined. Genomes of CAV were detected as contaminants in 6/32 live vaccines and in 1/3 inactivated vaccines. The CAV genome loads ranged from 6.4 to 173.4 per 50 ng of vaccine DNA (equivalent to 0.07 to 0.69 genome copies per dose of vaccine). Likewise, AGV2 genomes were detected in 9/32 live vaccines, with viral loads ranging from 93 to 156,187 per 50 ng of vaccine DNA (equivalent to 0.28-9176 genome copies per dose of vaccine). These findings provide evidence for the possibility of contamination of poultry vaccines with CAV and AGV2 and they also emphasize the need of searching for these agents in vaccines in order to ensure the absence of such potential contaminants.
Tipo de publicación:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
Nombre de substancia:0 (DNA, Viral); 0 (Vaccines); 0 (Vaccines, Attenuated); 9007-49-2 (DNA)


  9 / 22 MEDLINE  
              first record previous record next record last record
selecciona
para imprimir
Fotocopia
PubMed Central Texto completo
Texto completo
PMID:25246270
Autor:Chaabane W; Cieslar-Pobuda A; El-Gazzah M; Jain MV; Rzeszowska-Wolny J; Rafat M; Stetefeld J; Ghavami S; Los MJ
Dirección:Department of Clinical and Experimental Medicine (IKE), Division of Cell Biology, and Integrative Regenerative Medicine Center (IGEN), Linköping University, Linköping Sweden; Department of Biology, Faculty of Sciences, Tunis University, Tunis, Tunisia.
Título:Human-gyrovirus-Apoptin triggers mitochondrial death pathway--Nur77 is required for apoptosis triggering.
Fuente:Neoplasia; 16(9):679-93, 2014 Sep.
ISSN:1476-5586
País de publicación:United States
Idioma:eng
Resumen:The human gyrovirus derived protein Apoptin (HGV-Apoptin) a homologue of the chicken anemia virus Apoptin (CAV-Apoptin), a protein with high cancer cells selective toxicity, triggers apoptosis selectively in cancer cells. In this paper, we show that HGV-Apoptin acts independently from the death receptor pathway as it induces apoptosis in similar rates in Jurkat cells deficient in either FADD (fas-associated death domain) function or caspase-8 (key players of the extrinsic pathway) and their parental clones. HGV-Apoptin induces apoptosis via the activation of the mitochondrial intrinsic pathway. It induces both mitochondrial inner and outer membrane permebilization, characterized by the loss of the mitochondrial potential and the release into cytoplasm of the pro-apoptotic molecules including apoptosis inducing factor and cytochrome c. HGV-Apoptin acts via the apoptosome, as lack of expression of apoptotic protease-activating factor 1 in murine embryonic fibroblast strongly protected the cells from HGV-Apoptin-induced apoptosis. Moreover, QVD-oph a broad-spectrum caspase inhibitor delayed HGV-Apoptin-induced death. On the other hand, overexpression of the anti-apoptotic BCL-XL confers resistance to HGV-Apoptin-induced cell death. In contrast, cells that lack the expression of the pro-apoptotic BAX and BAK are protected from HGV-Apoptin induced apoptosis. Furthermore, HGV-Apoptin acts independently from p53 signal but triggers the cytoplasmic translocation of Nur77. Taking together these data indicate that HGV-Apoptin acts through the mitochondrial pathway, in a caspase-dependent manner but independently from the death receptor pathway.
Tipo de publicación:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
Nombre de substancia:0 (AIFM1 protein, human); 0 (Apoptosis Inducing Factor); 0 (Nuclear Receptor Subfamily 4, Group A, Member 1); 0 (Proto-Oncogene Proteins c-bcl-2); 0 (Receptors, Death Domain); 0 (Viral Proteins); 9007-43-6 (Cytochromes c); EC 3.4.22.- (Caspases)


  10 / 22 MEDLINE  
              first record previous record
selecciona
para imprimir
Fotocopia
Texto completo
PMID:25164066
Autor:Rollano Peñaloza OM; Lewandowska M; Stetefeld J; Ossysek K; Madej M; Bereta J; Sobczak M; Shojaei S; Ghavami S; Los MJ
Dirección:Department Clinical & Experimental Medicine, Division of Cell Biology, and Integrative Regenerative Medical Center, Linköping University, Linköping, Sweden; Instituto de Biologia Molecular y Biotecnologia, La Paz, Bolivia.
Título:Apoptins: selective anticancer agents.
Fuente:Trends Mol Med; 20(9):519-28, 2014 Sep.
ISSN:1471-499X
País de publicación:England
Idioma:eng
Resumen:Therapies that selectively target cancer cells for death have been the center of intense research recently. One potential therapy may involve apoptin proteins, which are able to induce apoptosis in cancer cells leaving normal cells unharmed. Apoptin was originally discovered in the Chicken anemia virus (CAV); however, human gyroviruses (HGyV) have recently been found that also harbor apoptin-like proteins. Although the cancer cell specific activity of these apoptins appears to be well conserved, the precise functions and mechanisms of action are yet to be fully elucidated. Strategies for both delivering apoptin to treat tumors and disseminating the protein inside the tumor body are now being developed, and have shown promise in preclinical animal studies.
Tipo de publicación:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
Nombre de substancia:0 (Antineoplastic Agents); 0 (Capsid Proteins); 0 (VP3 protein, Chicken anemia virus); 0 (Viral Proteins)



página 1 de 3 va a la página          
   


Refinar la búsqueda
  Base de datos : MEDLINE Formulario avanzado   

    Buscar en el campo  
1  
2
3
 
           



Search engine: iAH v2.6 powered by WWWISIS

BIREME/OPS/OMS - Centro Latinoamericano y del Caribe de Información en Ciencias de la Salud