Database : MEDLINE
Search on : C05.500.460.827 [DeCS Category]
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  1 / 1729 MEDLINE  
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PMID:29364827
Author:Verma R; Jena AK; Singh SP; Utreja AK; Rattan V
Address:Department of Orthodontics and Dentofacial Orthopedics, Gian Sagar Dental College and Hospital, Ramnagar, Banur, Punjab, India. rashmiverma.in@gmail.com.
Title:Multidisciplinary management of post-ankylosis malocclusion and mandibular deformity.
Source:J Clin Orthod; 51(12):809-819, 2017 Dec.
ISSN:0022-3875
Country of publication:United States
Language:eng
Publication type:CASE REPORTS; JOURNAL ARTICLE


  2 / 1729 MEDLINE  
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PMID:29407503
Author:Balkhande PB; Lakkakula BVKS; Chitharanjan AB
Address:Department of Orthodontics and Dentofacial Orthopaedics, Sri Ramachandra University, Porur, Chennai, India.
Title:Relationship between matrilin-1 gene polymorphisms and mandibular retrognathism.
Source:Am J Orthod Dentofacial Orthop; 153(2):255-261.e1, 2018 Feb.
ISSN:1097-6752
Country of publication:United States
Language:eng
Abstract:INTRODUCTION: Mandibular retrognathism is a type of malocclusion that refers to an abnormal posterior position of the mandible as a result of a developmental abnormality. From the literature, it is evident that the mandibular growth pattern is determined by the intramembranous ossification of the mandibular body and endochondral ossification of the condyle. Matrilin-1 is a cartilage extracellular matrix protein, and matrilin-1 gene (MATN1) polymorphisms have been found to be involved in dental malocclusions of humans. In this study, we aimed to examine the association between MATN1 polymorphisms and the risk of mandibular retrognathism, in a case-control study with a South Indian population. METHODS: Eighty-one patients with mandibular retrognathism (SNB, <78°) and 71 controls having an orthognathic mandible (SNB, 80° ± 2°) were recruited. In both the patient and control groups, subjects with an orthognathic maxilla (SNA, 82° ± 2°) were included. Three single nucleotide polymorphisms of the MATN1 gene (rs1149048, rs1149042, and rs1065755) were genotyped using polymerase chain reaction-restriction fragment length polymorphism. The statistical association analysis was performed using the chi-square test. Pair-wise linkage disequilibrium was computed, and haplotypes were compared between subjects and controls. Nonparametric tests were used to compare cephalometric measurements between groups. RESULTS: No polymorphic site deviated from Hardy-Weinberg equilibrium in the controls. The rs1149042 genotypes and alleles were found to be associated with reduced risk of mandibular retrognathism. Furthermore, rs1149042 genotypes were associated with mandibular measurements (SNB and ANB). There was no strong and consistent linkage disequilibrium linkage disequilibrium across two different single nucleotide polymorphisms and haplotypes were not associated with mandibular retrognathism. CONCLUSIONS: The results of our study suggest an association between the MATN1 gene polymorphisms and mandibular retrognathism.
Publication type:JOURNAL ARTICLE
Name of substance:0 (Matrilin Proteins)


  3 / 1729 MEDLINE  
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PMID:28468148
Author:Ligh CA; Swanson J; Yu JW; Samra F; Bartlett SP; Taylor JA
Address:*Division of Plastic and Reconstructive Surgery, Department of Surgery, The Children's Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA †Division of Plastic and Reconstructive Surgery, Department of Surgery, University of Southern California, Los Angeles, CA.
Title:A Morphological Classification Scheme for the Mandibular Hypoplasia in Treacher Collins Syndrome.
Source:J Craniofac Surg; 28(3):683-687, 2017 May.
ISSN:1536-3732
Country of publication:United States
Language:eng
Abstract:BACKGROUND: Mandibular hypoplasia is a hallmark of Treacher Collins syndrome (TCS), and its severity accounts for significant functional morbidity. The purpose of this study is to develop a mandibular classification scheme. METHODS: A classification scheme was designed based on three-dimensional computed tomography (3D-CT) scans to assess 3 characteristic features: degree of condylar hypoplasia, mandibular plane angle (condylion-gonion-menton), and degree of retrognathia (sella-nasion-B point angle). Each category was graded from I to IV and a composite mandible classification was determined by the median value among the 3 component grades. RESULTS: Twenty patients with TCS, aged 1 month to 20 years, with at least one 3D-CT prior to mandibular surgery were studied. Overall, 33 3D-CTs were evaluated and ordered from least to most severe phenotype with 10 (30%) Grade 1 (least severe), 14 (42%) Grade 2, 7 (21%) Grade 3, and 2 (7%) Grade 4 (most severe). Seven patients had at least 2 longitudinal scans encompassing an average 5.7 (range 5-11) years of growth. Despite increasing age, mandibular classification (both components and composite) remained stable in those patients over time (P = 0.2182). CONCLUSION: The authors present a classification scheme for the TCS mandible based on degree of condylar hypoplasia, mandibular plane angle (Co-Go-Me angle), and retrognathia (SNB angle). While there is a natural progression of the mandibular morphology with age, patients followed longitudinally demonstrate consistency in their classification. Further work is needed to determine the classification scheme's validity, generalizability, and overall utility.
Publication type:JOURNAL ARTICLE


  4 / 1729 MEDLINE  
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PMID:28962730
Author:Yüksel AG; Iskender SY; Kuitert R; Papadopoulou AK; Dalci K; Darendeliler MA; Dalci O
Address:Department of Orthodontics, Academisch Centrum Tandheelkunde Amsterdam, Amsterdam, The Netherlands. Electronic address: aylinyuksel91@gmail.com.
Title:Differences in attractiveness comparing female profile modifications of Class II Division 1 malocclusion.
Source:Am J Orthod Dentofacial Orthop; 152(4):471-476, 2017 Oct.
ISSN:1097-6752
Country of publication:United States
Language:eng
Abstract:INTRODUCTION: Our objective was to study the perceptions of laypeople for digital alterations and the amount of nasolabial angle increase that is tolerable and how much chin-neck length increase is needed to achieve a desirable profile in Class II Division 1 women with mandibular retrognathia. METHODS: The profile image of a white woman with a Class II Division 1 mandibular rethrognatic profile was digitally modified to create 6 images: 3 with stepwise increased nasolabial angles of 113°, 121°, and 129°, and 3 with stepwise increased chin-neck distances of 51, 54, and 57 mm. These images were assessed and ranked by 155 white laypeople. RESULTS: The baseline profile was judged significantly as the least attractive. A nasolabial angle of 129° was judged as unattractive as the baseline profile. Profiles with a chin-neck length of 54 and 57 mm were equally judged as most attractive. CONCLUSIONS: The untreated (baseline) profile was found to be least esthetic, as well as the profile with the largest nasolabial angle. Nasolabial angle increases up to 121° seem to be acceptable. Profiles simulating a chin-neck length increase as produced by surgery seem to be most favored.
Publication type:COMPARATIVE STUDY; JOURNAL ARTICLE


  5 / 1729 MEDLINE  
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PMID:28863921
Author:Jung MH
Address:Department of Orthodontics, Dental Research Institute and School of Dentistry, Seoul National University, Seoul, Korea; private practice, Seoul, Korea. Electronic address: fortit@naver.com.
Title:Fixed-functional appliance treatment combined with growth hormone therapy.
Source:Am J Orthod Dentofacial Orthop; 152(3):402-412, 2017 Sep.
ISSN:1097-6752
Country of publication:United States
Language:eng
Abstract:The purpose of this study was to illustrate the effects of growth hormone (GH) therapy and fixed functional appliance treatment in a 13-year-old Class II malocclusion patient without GH deficiency. GH has been shown to effectively increase endochondral growth and induce a more prognathic skeletal pattern. Although a major concern in Class II retrognathic patients is chin deficiency, long-term studies have shown that the mandibular growth enhancement effects of functional appliances are clinically insignificant. This case report demonstrates that the mandible grew significantly during fixed functional appliance treatment combined with GH therapy, with stable results during 2 years 11 months of retention. More studies are needed to evaluate GH therapy as a supplement in Class II treatment.
Publication type:CASE REPORTS; JOURNAL ARTICLE
Name of substance:12629-01-5 (Human Growth Hormone)


  6 / 1729 MEDLINE  
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PMID:28483230
Author:Xiang M; Hu B; Liu Y; Sun J; Song J
Address:College of Stomatology, Chongqing Medical University, Chongqing, China; Chongqing Key Laboratory of Oral Diseases and Biomedical Sciences, Chongqing, China; Chongqing Municipal Key Laboratory of Oral Biomedical Engineering of Higher Education, Chongqing, China.
Title:Changes in airway dimensions following functional appliances in growing patients with skeletal class II malocclusion: A systematic review and meta-analysis.
Source:Int J Pediatr Otorhinolaryngol; 97:170-180, 2017 Jun.
ISSN:1872-8464
Country of publication:Ireland
Language:eng
Abstract:OBJECTIVES: The purpose of the study was to evaluate the treatment effects of functional appliances (FAs) on upper airway dimensions in growing Class II patients with mandibular retrognathism. METHODS: Five databases and the references of identified articles were electronically searched for relevant studies that met our eligibility criteria. The quality of the included studies was assessed using the Newcastle-Ottawa Scale. The effects of FAs on airway dimensions were combined by meta-analysis using the RevMan and STATA software. RESULTS: Seven studies (177 treated patients with mean age: 11.48 years and 153 untreated controls with mean age: 11.20 years) were included in this review. Compared to the control group, the oropharyngeal dimensions in the treatment group subjects were significantly increased at the superior pharyngeal space (MD = 1.73 mm/year, 95% CI, 1.13-2.32 mm, P < 0.00001), middle pharyngeal space (MD = 1.68 mm/year, 95% CI, 1.13-2.23 mm, P < 0.00001) and inferior pharyngeal space (MD = 1.21 mm/year, 95% CI, 0.48-1.95 mm, P = 0.001). No significant differences were found in nasopharyngeal and hypopharyngeal dimensions and the position of hyoid bone (P > 0.05). Soft palate length and soft palate inclination were improved significantly in the treatment group (P < 0.05). CONCLUSIONS: The results showed that FAs can enlarge the upper airway dimensions, specifically in the oropharyngeal region, in growing subjects with skeletal Class II malocclusion. The early intervention for mandibular retrognathism with FAs may help enlarge the airway dimensions and decrease potential risk of obstructive sleep apnea syndrome for growing patients in the future.
Publication type:JOURNAL ARTICLE; META-ANALYSIS; REVIEW


  7 / 1729 MEDLINE  
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PMID:28279055
Author:Yu X; Liu JQ; Yuan LJ; Mao LX; Zhu M; Fang B
Address:Department of Cranio-Maxilla Facial Science, Center of Cranio-Facial Orthodontics, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine & Shanghai Key Laboratory of Stomatology, Shanghai 200011, China (Present address: Department of Pediatric Dentistry, Shanghai Stomatologic
Title:[MRI analysis of the effect on mandibular retrusion with anterior disc displacement treated by using Herbst appliance].
Source:Zhonghua Kou Qiang Yi Xue Za Zhi; 52(3):171-175, 2017 Mar 09.
ISSN:1002-0098
Country of publication:China
Language:chi
Abstract:To investgate the effect of Herbst appliance on the growth and remodeling of the temporomandibular joint (TMJ) in class â…¡ patients with mandibular retrusion by using MRI. Between December 2010 and October 2014, 12 class â…¡ patients (11-16 years old) with mandibular retrusion were chosen. The patients were divided into two groups. The control group included 7 patients (14 joints) with normal disc condyle relationship and the anterior disc displacement (ADD) group included 5 patients (10 joints) with anterior disc displacement. The MRI images of TMJ were measured, including condylar height, joint space index and disc position ratio, before and after the treatment. The condylar height of the patients in the control group was significantly increased ( 0.001) after treatment, and no significant difference in joint space index ( 0.821) and disc position ratio ( 0.146) was found. The joint space index of the patients ([-14.70±8.82]% and [4.90±11.35]%) in ADD group changed significantly ( 0.001) after treatment, and no significant difference in condylar height ( 0.294) and disc position ratio ( 0.120) was found. The normal disc condyle relationship was beneficial to the reconstruction of the condylar process, and the increase of the condylar height. The condyle moved forward in patients with anterior disc displacement after treatment.
Publication type:JOURNAL ARTICLE


  8 / 1729 MEDLINE  
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PMID:28279051
Author:Fang B
Address:Department of Cranio-Maxilla Facial Science, Center of Cranio-Facial Orthodontics, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine & Shanghai Key Laboratory of Stomatology, Shanghai 200011, China.
Title:[Relationship between the mandibular hypoplasia and temporomandibular joint internal derangement in adolescents with skeletal class â…¡ malocclusion].
Source:Zhonghua Kou Qiang Yi Xue Za Zhi; 52(3):152-156, 2017 Mar 09.
ISSN:1002-0098
Country of publication:China
Language:chi
Abstract:Mandibular hypoplasia is very common clinically. Studies have reported that temporomandibular joint internal derangement (TMJID) might manifest as mandibular retrusion, and whether there is a direct correlation between them remains controversial in academia. On the other hand, for adolescent patients with skeletal class â…¡ malocclusion, the growth of mandible could be motivated by orthopedic force, and then the mandibular retrusion corrected. However, if TMJID is the direct cause of mandibular retrusion, orthopedic treatment will not have a significant effect on it. Base on literature review and analysis as well as our own research, this article will review the distribution of structural abnormalities of the temporomandibular joint in adolescents with mandibular hypoplasia and its association with skeletal class â…¡ malocclusion, as well as the effect of TMJID on the treatment of skeletal class â…¡ malocclusion in adolescents.
Publication type:JOURNAL ARTICLE; REVIEW


  9 / 1729 MEDLINE  
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PMID:28326709
Author:Weiwei C; Ting S; Zhen H; Jun W
Address:Dept. of Stomatology, Traditional Chinese Medicine and Western Medicine Combination Hospital of Nanchang City, Nanchang 330006, China.
Title:[Cone beam computed tomography analysis of the bony structure of the temporomandibular joint during two phase treatment with Herbst appliance].
Source:Hua Xi Kou Qiang Yi Xue Za Zhi; 34(5):498-501, 2016 Oct 01.
ISSN:1000-1182
Country of publication:China
Language:chi
Abstract:OBJECTIVE: This study assessed the effects of two-phase treatment with Herbst appliance on the bony structure of the temporomandibular joint via cone beam computed tomography (CBCT) analysis. METHODS: This study selected 15 patients exhibiting early permanent dentition and classⅡmalocclusion combined with mandibular retrusion treated by a two phase treatment (Herbst and fixed appliance). The CBCT scans of the patients were obtained at the following stages: 2 weeks before Herbst treatment (T1), at the start of treatment when the Herbst appliance was set in place (T2), immediately after removal of the Herbst appliance (T3), and immediately after removal of the edgewise appliance (T4). Three-dimensional reconstruction and related measurements were performed using InvivoDental software, and the acquired data were statistically analyzed. RESULTS: 1) CBCT showed a crescent-shaped hyperplasia at the posterior-superior border of the condyles that the outer edge was highly dense and the inner region was lowly dense in T3 in 14 patients (28 condyles). 2) In T3-T2 and T4-T1, the diameters of the anteroposterior condyles increased by 0.62 and 0.66 mm, respectively (P<0.01), and the condylar head height correspondingly increased by 0.54 and 0.53 mm (P<0.01). CONCLUSIONS: Condylar growth remodeling occurs during Herbst treatment.
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Publication type:JOURNAL ARTICLE


  10 / 1729 MEDLINE  
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PMID:27871712
Author:Lee KY; Park JH; Tai K; Chae JM
Address:Instructor, Department of Orthodontics, Dental Hospital, School of Dentistry, University of Wonkwang, Iksan, Korea.
Title:Treatment with Twin-block appliance followed by fixed appliance therapy in a growing Class II patient.
Source:Am J Orthod Dentofacial Orthop; 150(5):847-863, 2016 Nov.
ISSN:1097-6752
Country of publication:United States
Language:eng
Abstract:A girl, aged 11 years 4 months, with a skeletal Class II pattern and a severe overjet (10 mm) was treated with a Twin-block appliance. After 9 months of appliance therapy, the skeletal Class II was overcorrected. After 26 months of retention, when the occlusion was stable and the growth rate was diminishing, fixed orthodontic appliances using temporary skeletal anchorage devices were initiated. The total active treatment time with fixed orthodontic appliances was 30 months. Posttreatment records after 18 months demonstrated excellent stability: a functional occlusion and a pleasing facial balance. Cone-beam computed tomography was used to visualize temporomandibular joint adaptations after the functional and fixed orthodontic therapies.
Publication type:CASE REPORTS; JOURNAL ARTICLE



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