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[PMID]:29414271
[Au] Autor:Shoji K; Saitoh A
[Ad] Endereço:National Center for Child Health and Development, Tokyo, Japan shoji-k@ncchd.go.jp.
[Ti] Título:Herpetic Whitlow.
[So] Source:N Engl J Med;378(6):563, 2018 Feb 08.
[Is] ISSN:1533-4406
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Dermatoses da Mão/virologia
Herpes Simples
Herpesvirus Humano 1/isolamento & purificação
Língua/virologia
[Mh] Termos MeSH secundário: Feminino
Dedos/patologia
Herpes Simples/patologia
Seres Humanos
Lactente
Reação em Cadeia da Polimerase
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180214
[Lr] Data última revisão:
180214
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180208
[St] Status:MEDLINE
[do] DOI:10.1056/NEJMicm1711479


  2 / 25551 MEDLINE  
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[PMID]:29390590
[Au] Autor:Zhao G; Mi J; Rui Y; Pan X; Yao Q; Qiu Y
[Ad] Endereço:Department of Medicine, Soochow University, Suzhou.
[Ti] Título:Correlation of volumetric flow rate and skin blood flow with cold intolerance in digital replantation.
[So] Source:Medicine (Baltimore);96(51):e9477, 2017 Dec.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Cold intolerance is a common complication of digital replantation. The exact etiology is unclear, but it is considered to be multifactorial, including nonsurgical characteristics, vascular, and neurologic conditions. Blood flow may play a significant role in cold intolerance. This study was designed to evaluate the correlation of digital blood flow, including volumetric flow rate (VFR) and skin blood flow (SkBF), with cold intolerance in replanted fingers.A retrospective study was conducted among patients who underwent digital replantation between 2010 and 2013. Patients were selected into study cohort based on the inclusion criteria. Surgical data was collected on each patient, including age, sex, injury mechanism, amputation level, ischemia time, number of arteries repaired, and whether or not vascular crisis occurred. Patients were included as study cohort with both nerves repaired and without chronic disease. Cold intolerance was defined as a Cold Intolerance Symptom Severity (CISS) score over 30. The arterial flow velocity and caliber were measured by Color Doppler Ultrasound and the digital VFR was calculated. The SkBF was measured by Laser Speckle Imager. Both VFR and SkBF were calculated as a percentage of the contralateral fingers. Comparative study of surgical data and blood flow was performed between the patient with and without cold intolerance. Correlation between VFR and SkBF was also analyzed.A total of 93 patients met inclusion criteria for the study. Approximately, 42 patients were identified as having cold intolerance. Fingers that survived vascular crisis had a higher incidence of cold intolerance with a lower VFR and SkBF. The VFR was higher in 2-artery replantation, but the SkBF and incidence of cold intolerance did not differ significantly. No differences were found in age, sex, injury mechanism, amputation level, or ischemia time. Furthermore, no correlation was found between VFR and SkBF.Cold intolerance of digital replantation is associated with decreased SkBF and VFR in the replanted fingers, which survived vascular crisis. Further work will be focused on how vascular crisis cause the decreasing of SkBF and VFR and the increasing chance of cold intolerance.
[Mh] Termos MeSH primário: Amputação Traumática/cirurgia
Temperatura Baixa/efeitos adversos
Traumatismos dos Dedos/cirurgia
Reimplante
Pele/irrigação sanguínea
[Mh] Termos MeSH secundário: Adulto
Feminino
Dedos/irrigação sanguínea
Seres Humanos
Masculino
Fluxo Sanguíneo Regional
Reimplante/efeitos adversos
Estudos Retrospectivos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180212
[Lr] Data última revisão:
180212
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180203
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000009477


  3 / 25551 MEDLINE  
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[PMID]:29401917
[Au] Autor:Yuan X; Pu Y
[Ti] Título:Parallel lensless compressive imaging via deep convolutional neural networks.
[So] Source:Opt Express;26(2):1962-1977, 2018 Jan 22.
[Is] ISSN:1094-4087
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:We report a parallel lensless compressive imaging system, which enjoys real-time reconstruction using deep convolutional neural networks. A prototype composed of a low-cost LCD, 16 photo-diodes and isolation chambers, has been built. Each of these 16 channels captures a fraction of the scene with 16×16 pixels and they are performing in parallel. An efficient inversion algorithm based on deep convolutional neural networks is developed to reconstruct the image. We have demonstrated encouraging results using only 2% (relative to pixel numbers, e.g. 5 for a block with 16×16 pixels) measurements per sensor for digits and around 10% measurements per sensor for facial images.
[Mh] Termos MeSH primário: Algoritmos
Identificação Biométrica/métodos
Processamento de Imagem Assistida por Computador/métodos
Redes Neurais (Computação)
Fotografia/métodos
[Mh] Termos MeSH secundário: Identificação Biométrica/instrumentação
Desenho de Equipamento
Reconhecimento Facial
Dedos
Seres Humanos
Aprendizado de Máquina
Imagem Óptica/instrumentação
Imagem Óptica/métodos
Fotografia/instrumentação
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180208
[Lr] Data última revisão:
180208
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180207
[St] Status:MEDLINE
[do] DOI:10.1364/OE.26.001962


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[PMID]:28466542
[Au] Autor:Möckesch B; Connes P; Charlot K; Skinner S; Hardy-Dessources MD; Romana M; Jumet S; Petras M; Divialle-Doumdo L; Martin C; Tressières B; Tarer V; Hue O; Etienne-Julan M; Antoine S; Pialoux V
[Ad] Endereço:Laboratory ACTES (EA 3596), French West Indies University, Pointe-à-Pitre, Guadeloupe, France.
[Ti] Título:Association between oxidative stress and vascular reactivity in children with sickle cell anaemia and sickle haemoglobin C disease.
[So] Source:Br J Haematol;178(3):468-475, 2017 08.
[Is] ISSN:1365-2141
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Oxidative stress and haemolysis-associated nitric oxide (NO) depletion plays a crucial role in the development of vasculopathy in sickle cell anaemia (SS). However it remains unknown whether oxidative stress and haemolysis levels influence vascular function in patients with sickle haemoglobin C disease (SC). Microvascular response to heat (using Laser Doppler flowmetry on finger), oxidative stress biomarkers, NO metabolites, endothelin-1 and haematological parameters were compared between patients with SS and SC. Vascular function, oxidative and nitrosative markers were also measured in healthy (AA) children. SS and SC had increased plasma advanced oxidation protein products (AOPP), malondialdehyde, plasma antioxidant activities and NO end products, compared to AA. SC had lower catalase activity compared to AA and SS. Haemolytic rate, glutathione peroxidase and nitrotyrosine concentrations were significantly increased in children with SS compared to SC and AA. SS and SC had impaired microvascular reactivity compared to AA. In SS, the plateau phase of the response to local thermal heating was negatively associated with nitrotyrosine and AOPP. No association between vascular function parameters and oxidative stress markers was observed in SC. Mild haemolysis in SC, compared to SS, may limit oxidative and nitrosative stress and could explain the better preserved microvascular function in this group.
[Mh] Termos MeSH primário: Anemia Falciforme/fisiopatologia
Estresse Oxidativo/fisiologia
[Mh] Termos MeSH secundário: Adolescente
Produtos da Oxidação Avançada de Proteínas/sangue
Antioxidantes/metabolismo
Viscosidade Sanguínea/fisiologia
Estudos de Casos e Controles
Criança
Endotelina-1/sangue
Feminino
Dedos/irrigação sanguínea
Doença da Hemoglobina SC/fisiopatologia
Hemólise/fisiologia
Seres Humanos
Fluxometria por Laser-Doppler/métodos
Masculino
Malondialdeído/sangue
Microcirculação/fisiologia
Óxido Nítrico/sangue
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Advanced Oxidation Protein Products); 0 (Antioxidants); 0 (Endothelin-1); 31C4KY9ESH (Nitric Oxide); 4Y8F71G49Q (Malondialdehyde)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:180209
[Lr] Data última revisão:
180209
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170504
[St] Status:MEDLINE
[do] DOI:10.1111/bjh.14693


  5 / 25551 MEDLINE  
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[PMID]:29324829
[Au] Autor:Bao X; Zhou Y; Wang Y; Zhang J; Lü X; Wang Z
[Ad] Endereço:State Key Laboratory of Bioelectronics, Southeast University, Nanjing, People's Republic of China.
[Ti] Título:Electrode placement on the forearm for selective stimulation of finger extension/flexion.
[So] Source:PLoS One;13(1):e0190936, 2018.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:It is still challenging to achieve a complex grasp or fine finger control by using surface functional electrical stimulation (FES), which usually requires a precise electrode configuration under laboratory or clinical settings. The goals of this study are as follows: 1) to study the possibility of selectively activating individual fingers; 2) to investigate whether the current activation threshold and selective range of individual fingers are affected by two factors: changes in the electrode position and forearm rotation (pronation, neutral and supination); and 3) to explore a theoretical model for guidance of the electrode placement used for selective activation of individual fingers. A coordinate system with more than 400 grid points was established over the forearm skin surface. A searching procedure was used to traverse all grid points to identify the stimulation points for finger extension/flexion by applying monophasic stimulation pulses. Some of the stimulation points for finger extension and flexion were selected and tested in their respective two different forearm postures according to the number and the type of the activated fingers and the strength of finger action response to the electrical stimulation at the stimulation point. The activation thresholds and current ranges of the selectively activated finger at each stimulation point were determined by visual analysis. The stimulation points were divided into three groups ("Low", "Medium" and "High") according to the thresholds of the 1st activated fingers. The angles produced by the selectively activated finger within selective current ranges were measured and analyzed. Selective stimulation of extension/flexion is possible for most fingers. Small changes in electrode position and forearm rotation have no significant effect on the threshold amplitude and the current range for the selective activation of most fingers (p > 0.05). The current range is the largest (more than 2 mA) for selective activation of the thumb, followed by those for the index, ring, middle and little fingers. The stimulation points in the "Low" group for all five fingers lead to noticeable finger angles at low current intensity, especially for the index, middle, and ring fingers. The slopes of the finger angle variation in the "Low" group for digits 2~4 are inversely proportional to the current intensity, whereas the slopes of the finger angle variation in other groups and in all groups for the thumb and little finger are proportional to the current intensity. It is possible to selectively activate the extension/flexion of most fingers by stimulating the forearm muscles. The physiological characteristics of each finger should be considered when placing the negative electrode for selective stimulation of individual fingers. The electrode placement used for the selective activation of individual fingers should not be confined to the location with the lowest activation threshold.
[Mh] Termos MeSH primário: Estimulação Elétrica/métodos
Eletrodos
Dedos/fisiologia
Antebraço/fisiologia
Movimento/fisiologia
Contração Muscular/fisiologia
[Mh] Termos MeSH secundário: Adulto
Análise de Variância
Fenômenos Biomecânicos
Estimulação Elétrica/instrumentação
Feminino
Antebraço/anatomia & histologia
Seres Humanos
Masculino
Músculo Esquelético/fisiologia
Tamanho do Órgão
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180206
[Lr] Data última revisão:
180206
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180112
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0190936


  6 / 25551 MEDLINE  
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[PMID]:29375114
[Au] Autor:Yamashita M; Eguchi K; Ogawa M; Takahashi K; Nagai M; Shimpo M; Misawa Y; Kario K
[Ad] Endereço:Department of Medicine, Jichi Medical University School of Medicine.
[Ti] Título:A Case of Left Atrial Myxoma Whose Initial Symptom Was Finger Ischemic Symptom.
[So] Source:Int Heart J;59(1):233-236, 2018.
[Is] ISSN:1349-3299
[Cp] País de publicação:Japan
[La] Idioma:eng
[Ab] Resumo:We experienced a 45-year-old Japanese man who was transferred to our hospital complaining of acute onset of pain and pallor in the right lower limb. Two years earlier, he had complained of repetitive pain at rest and pallor in the left third and fourth fingers. The physical exam and angiography demonstrated occlusion of finger arteries, however we could not reach final diagnosis. Acute arterial occlusive disease in the right lower limb was suspected. Transthoracic echocardiography demonstrated a gross tumor in the left atrium, which suggested left atrial myxoma. An emergency tumorectomy was successfully conducted. Pathologically, the fragile tumor and resultant thrombosis could have caused the patient's peripheral circulatory failure at least two years prior to this episode. A rigorous systemic survey is important even when the ischemic symptom is localized in peripheral circulation.
[Mh] Termos MeSH primário: Dedos/irrigação sanguínea
Neoplasias Cardíacas/complicações
Isquemia/etiologia
Mixoma/complicações
[Mh] Termos MeSH secundário: Procedimentos Cirúrgicos Cardíacos
Ecocardiografia
Átrios do Coração
Neoplasias Cardíacas/diagnóstico
Neoplasias Cardíacas/cirurgia
Seres Humanos
Isquemia/diagnóstico
Imagem por Ressonância Magnética
Masculino
Meia-Idade
Mixoma/diagnóstico
Mixoma/cirurgia
Tomografia Computadorizada por Raios X
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180205
[Lr] Data última revisão:
180205
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180130
[St] Status:MEDLINE
[do] DOI:10.1536/ihj.16-394


  7 / 25551 MEDLINE  
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[PMID]:28468208
[Au] Autor:Sisti A; Freda N; Giacomina A; Gatti GL
[Ad] Endereço:Plastic and Reconstructive Surgery, Santa Chiara Hospital, Pisa, Italy.
[Ti] Título:Popliteal Pterygium Syndrome With Syngnathia.
[So] Source:J Craniofac Surg;28(3):e250-e251, 2017 May.
[Is] ISSN:1536-3732
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Popliteal pterygium syndrome is a condition characterized by skin webs on the popliteal fossa, which may impair mobility unless surgically repaired. Affected individuals may also have syndactyly on the fingers and/or toes. Most people with this disorder present cleft lip and cleft palate and they can have syngnathia, that is a congenital adhesion between maxilla and mandible by fibrous bands, which affects the opening of the mouth. The case that we report is about a 2-month-old male, who presented skin webs bilaterally on the popliteal fossa, syndactyly between the IV and the V toe of the right foot and between the III and the IV toe of the left foot, and genital malformations. He was born with complete bilateral cleft lip and complete cleft palate on the left side and incomplete cleft palate on the right side and syngnathia with 4 fibrous bands between the mandibular arch and the maxilla arch on the right side, which affected the opening of the mouth. The case of our patient is very interesting because there have been few reported patients affected by popliteal pterygium syndrome with syngnathia.
[Mh] Termos MeSH primário: Anormalidades Múltiplas/diagnóstico
Fenda Labial/diagnóstico
Fissura Palatina/diagnóstico
Anormalidades do Olho/diagnóstico
Dedos/anormalidades
Articulação do Joelho/anormalidades
Deformidades Congênitas das Extremidades Inferiores/diagnóstico
Mandíbula/anormalidades
Maxila/anormalidades
Sindactilia/diagnóstico
Anormalidades Urogenitais/diagnóstico
[Mh] Termos MeSH secundário: Seres Humanos
Lactente
Masculino
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180202
[Lr] Data última revisão:
180202
[Sb] Subgrupo de revista:D
[Da] Data de entrada para processamento:170505
[St] Status:MEDLINE
[do] DOI:10.1097/SCS.0000000000003473


  8 / 25551 MEDLINE  
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[PMID]:27778048
[Au] Autor:Parsa B; Zatsiorsky VM; Latash ML
[Ad] Endereço:Department of Kinesiology, Rec.Hall-268N, The Pennsylvania State University, University Park, PA, 16802, USA.
[Ti] Título:Optimality and stability of intentional and unintentional actions: II. Motor equivalence and structure of variance.
[So] Source:Exp Brain Res;235(2):457-470, 2017 Feb.
[Is] ISSN:1432-1106
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:We address the nature of unintentional changes in performance in two papers. This second paper tested hypotheses related to stability of task-specific performance variables estimated using the framework of the uncontrolled manifold (UCM) hypothesis. Our first hypothesis was that selective stability of performance variables would be observed even when the magnitudes of those variables drifted unintentionally because of the lack of visual feedback. Our second hypothesis was that stability of a variable would depend on the number of explicit task constraints. Subjects performed four-finger isometric pressing tasks that required the accurate production of a combination of total moment and total force with natural or modified finger involvement under full visual feedback, which was removed later for some or all of the salient variables. We used inter-trial analysis of variance and drifts in the space of finger forces within the UCM and within the orthogonal to the UCM space. The two variance components were used to estimate a synergy index stabilizing the force/moment combination, while the two drift components were used to estimate motor equivalent and non-motor equivalent force changes, respectively. Without visual feedback, both force and moment drifted toward lower absolute magnitudes. The non-motor equivalent component of motion in the finger force space was larger than the motor equivalent component for variables that stopped receiving visual feedback. In contrast, variables that continued to receive visual feedback showed larger motor equivalent component, compared to non-motor equivalent component, over the same time interval. These data falsified the first hypothesis; indeed, selective stabilization of a variable over the duration of a trial allows expecting comparably large motor equivalent components both with and without visual feedback. Adding a new constraint (presented as a target magnitude of middle finger force) resulted in a drop in the synergy index in support of the second hypothesis. We interpret the force drift as a natural relaxation process toward states with lower potential energy in the physical (physiological) system involved in the task. The results show that presenting sensory feedback on a performance variable makes synergies stabilizing that variable dependent on that particular sensory feedback.
[Mh] Termos MeSH primário: Intenção
Movimento/fisiologia
Desempenho Psicomotor/fisiologia
[Mh] Termos MeSH secundário: Adulto
Análise de Variância
Retroalimentação Sensorial/fisiologia
Feminino
Dedos/fisiologia
Seres Humanos
Masculino
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:180201
[Lr] Data última revisão:
180201
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161026
[St] Status:MEDLINE
[do] DOI:10.1007/s00221-016-4806-2


  9 / 25551 MEDLINE  
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[PMID]:29320504
[Au] Autor:Tonen-Wolyec S; Batina-Agasa S; Muwonga J; Fwamba N'kulu F; Mboumba Bouassa RS; Bélec L
[Ad] Endereço:Ecole Doctorale Régionale D'Afrique Centrale en Infectiologie Tropicale, Franceville, Gabon.
[Ti] Título:Evaluation of the practicability and virological performance of finger-stick whole-blood HIV self-testing in French-speaking sub-Saharan Africa.
[So] Source:PLoS One;13(1):e0189475, 2018.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Opportunities for HIV testing could be enhanced by offering HIV self-testing (HIVST) in populations that fear stigma and discrimination when accessing conventional HIV counselling and testing in health care facilities. Field experience with HIVST has not yet been reported in French-speaking African countries. METHODS: The practicability of HIVST was assessed using the prototype the Exacto® Test HIV (Biosynex, Strasbourg, France) self-test in 322 adults living in Kisangani and Bunia, Democratic Republic of the Congo, according to World Health Organization's recommendations. Simplified and easy-to-read leaflet was translated in French, Lingala and Swahili. RESULTS: Forty-nine percent of participants read the instructions for use in French, while 17.1% and 33.9% read the instructions in Lingala and Swahili, respectively. The instructions for use were correctly understood in 79.5% of cases. The majority (98.4%) correctly performed the HIV self-test; however, 20.8% asked for oral assistance. Most of the participants (95.3%) found that performing the self-test was easy, while 4.7% found it difficult. Overall, the results were correctly interpreted in 90.2% of cases. Among the positive, negative, and invalid self-tests, misinterpretation occurred in 6.5%, 11.2%, and 16.0% of cases, respectively (P<0.0001). The Cohen's κ coefficient was 0.84. The main obstacle for HIVST was educational level, with execution and interpretation difficulties occurring among poorly educated people. The Exacto® Test HIV self-test showed 100.0% (95% CI; 98.8-100.0) sensitivity and 99.2% (95% CI; 97.5-99.8) specificity. CONCLUSIONS: Our field observations demonstrate: (i) the need to adapt the instructions for use to the Congolese general public, including adding educational pictograms as well as instructions for use in the local vernacular language(s); (ii) frequent difficulties understanding the instructions for use in addition to frequent misinterpretation of test results; and (iii) the generally good practicability of the HIV self-test despite some limitations. Supervised use of HIVST is recommended among poorly-educated people.
[Mh] Termos MeSH primário: Sorodiagnóstico da AIDS/métodos
Dedos
Infecções por HIV/diagnóstico
Autocuidado
[Mh] Termos MeSH secundário: Adolescente
Adulto
República Democrática do Congo
Feminino
Infecções por HIV/sangue
Seres Humanos
Masculino
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180129
[Lr] Data última revisão:
180129
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180111
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0189475


  10 / 25551 MEDLINE  
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[PMID]:29298145
[Au] Autor:Kennedy KR; Wang AL
[Ad] Endereço:University of Alabama at Birmingham, Birmingham, AL kcreal@uab.edu.
[Ti] Título:Poland Syndrome.
[So] Source:N Engl J Med;378(1):72, 2018 Jan 04.
[Is] ISSN:1533-4406
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Dedos/anormalidades
Doenças Musculares
Músculos Peitorais/anormalidades
Síndrome de Poland/patologia
[Mh] Termos MeSH secundário: Idoso de 80 Anos ou mais
Seres Humanos
Masculino
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180118
[Lr] Data última revisão:
180118
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180104
[St] Status:MEDLINE



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