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Pesquisa : A01.923.047.025.600.700 [Categoria DeCS]
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  1 / 12 MEDLINE  
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[PMID]:26077915
[Au] Autor:Doud AN; Levine EA; Fino NF; Stewart JH; Shen P; Votanopoulos KI
[Ad] Endereço:Surgical Oncology Service, Department of General Surgery, Wake Forest University, Winston-Salem, NC, 27157, USA. adoud@wakehealth.edu.
[Ti] Título:Stoma Creation and Reversal After Cytoreductive Surgery with Hyperthermic Intraperitoneal Chemotherapy.
[So] Source:Ann Surg Oncol;23(2):503-10, 2016 Feb.
[Is] ISSN:1534-4681
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:INTRODUCTION: Cytoreductive surgery with heated intraperitoneal chemotherapy (CRS/HIPEC) often includes stoma creation. We evaluated the indications, morbidity, and mortality associated with stoma creation and reversal after CRS/HIPEC. METHODS: Retrospective analysis of a prospective database of 1149 CRS-HIPEC procedures was performed. Patient demographics, type of malignancy, comorbidities, Clavien-graded morbidity, mortality, indications for stoma creation, and outcomes of subsequent reversal were abstracted. RESULTS: Sixteen percent (186/1149) of CRS/HIPEC procedures included stoma creation, whereas 1.1 % (11/963) of patients without initial stoma creation developed anastomotic leaks requiring stoma. Patients who required a stoma had worse preoperative performance status (ECOG 0/1: 77.2 vs. 86.1 %, p = 0.002), greater burden of disease (PCI 17.6 vs. 12.9, p < 0.0001), and were more likely to have R2 resections (74.5 vs. 48.8 %, p < 0.0001) than those without stoma creation. Stomas were intended to be permanent in 17.5 % (35/199). Of 164 patients with potentially reversible ostomies, only 26.2 % (43/164) underwent reversal. Disease progression (43/164, 26.2 %) and death (40/164, 24.3 %) most commonly precluded reversal. After reversal, 27.9 % (12/43) suffered a Clavien I/II morbidity, 27.9 % (12/43) suffered Clavien III/IV morbidity, and 30-day mortality was 4.7 % (2/43). Anastomotic leak occurred after 9 % (3/33) of ileostomy and 10 % (1/10) of colostomy reversals. CONCLUSIONS: Stomas are more common among CRS/HIPEC patients with a high burden of disease and poor functional status. Reversal is uncommon and is associated with significant major morbidity. Preoperative counseling for those with high disease burden and poor functional status should include the risk of permanent stoma.
[Mh] Termos MeSH primário: Neoplasias Peritoneais/patologia
Estomas Peritoneais/patologia
[Mh] Termos MeSH secundário: Biomarcadores Tumorais/análise
Terapia Combinada
Feminino
Seguimentos
Seres Humanos
Técnicas Imunoenzimáticas
Masculino
Meia-Idade
Estadiamento de Neoplasias
Neoplasias Peritoneais/cirurgia
Neoplasias Peritoneais/terapia
Estomas Peritoneais/cirurgia
Prognóstico
Estudos Prospectivos
Estudos Retrospectivos
Taxa de Sobrevida
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL
[Nm] Nome de substância:
0 (Biomarkers, Tumor)
[Em] Mês de entrada:1610
[Cu] Atualização por classe:170201
[Lr] Data última revisão:
170201
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150617
[St] Status:MEDLINE
[do] DOI:10.1245/s10434-015-4674-1


  2 / 12 MEDLINE  
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[PMID]:26158998
[Au] Autor:McLean J
[Ti] Título:Case closed: An economical treatment protocol for peristomal skin excoriation.
[So] Source:Ostomy Wound Manage;61(5):12,14, 2015 May.
[Is] ISSN:1943-2720
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Protocolos Clínicos/normas
Curativos Oclusivos/normas
Estomas Peritoneais/efeitos dos fármacos
Estomas Peritoneais/lesões
Dermatopatias/economia
Pele/lesões
[Mh] Termos MeSH secundário: Idoso
Violeta de Genciana/uso terapêutico
Seres Humanos
Masculino
Azul de Metileno/uso terapêutico
Manejo da Dor/métodos
Compostos de Prata/uso terapêutico
Pele/efeitos dos fármacos
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Silver Compounds); J4Z741D6O5 (Gentian Violet); T42P99266K (Methylene Blue)
[Em] Mês de entrada:1609
[Cu] Atualização por classe:150709
[Lr] Data última revisão:
150709
[Sb] Subgrupo de revista:N
[Da] Data de entrada para processamento:150711
[St] Status:MEDLINE


  3 / 12 MEDLINE  
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[PMID]:25807922
[Au] Autor:Ping Z; Jiang T; Wang C; Chen Z; Chen Z; Wang J; Wang L; Wang B; Xu D; Liu C; Li Z; Li JC
[Ad] Endereço:Department of Histology and Embryology, Institute of Cell Biology, Zhejiang University, Hangzhou, 310058, China.
[Ti] Título:The discovery of the synovial lymphatic stomata and lymphatic reabsorption in knee effusion.
[So] Source:Microsc Res Tech;78(6):479-84, 2015 Jun.
[Is] ISSN:1097-0029
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:To illustrate the mechanism of lymphatic reabsorption in knee joint effusion. The current investigation employed transmission electron microscopy (TEM) and scanning electron microscopy (SEM) techniques to reveal the ultrastructure of the knee synovial membrane in New Zealand rabbits and human. Ultrastructural changes of the synovial lymphatic stomata were observed by using trypan blue absorption and sodium hydroxide (NaOH) digestion methods, and the animal models of synovitis. New Zealand rabbits and human synovial membranes were composed of two types of synovial cells: type A and type B. No lymphatic stomata were found among type A synovial cells, whereas lymphatic stomata with the diameters ranging 0.74-3.26 µm were found in type B synovial cells, and some stomata were closed. After the NaOH digestion, a number of sieve pores, similar to lymphatic stomata in size and shape, were observed in the dense fibrous connective tissue underneath the type B synovial cells. After injecting trypan blue into the rabbit knee joint cavity, absorption of trypan blue through the lymphatic stomata was observed, suggesting the absorption function of the synovial lymphatic stomata. In the rabbit knee joint synovitis models, the synovial lymphatic stomata diameter enlarged. Some macrophages migrated from the lymphatic stomata, indicating that the synovial lymphatic stomata were involved in the joint effusion absorption and inflammatory response. Our study is the first to report the existence of synovial lymphatic stomata in the New Zealand rabbits and human knee joints. Lymphatic stomata may have an important role in the reabsorption of joint effusion.
[Mh] Termos MeSH primário: Líquido Ascítico/metabolismo
Articulação do Joelho/ultraestrutura
Estomas Peritoneais/ultraestrutura
Membrana Sinovial/ultraestrutura
Sinovite/patologia
[Mh] Termos MeSH secundário: Animais
Transporte Biológico
Seres Humanos
Microscopia Eletrônica de Varredura
Microscopia Eletrônica de Transmissão
Coelhos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1604
[Cu] Atualização por classe:150527
[Lr] Data última revisão:
150527
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150327
[St] Status:MEDLINE
[do] DOI:10.1002/jemt.22497


  4 / 12 MEDLINE  
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[PMID]:25526320
[Au] Autor:Oshiro H; Miura M; Iobe H; Kudo T; Shimazu Y; Aoba T; Okudela K; Nagahama K; Sakamaki K; Yoshida M; Nagao T; Nakaya T; Kurata A; Ohtani O
[Ad] Endereço:1 Department of Anatomic Pathology, Tokyo Medical University , Tokyo, Japan .
[Ti] Título:Lymphatic Stomata in the Adult Human Pulmonary Ligament.
[So] Source:Lymphat Res Biol;13(2):137-45, 2015 Jun.
[Is] ISSN:1557-8585
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Lymphatic stomata are small lymphatic openings in the serosal membrane that communicate with the serosal cavity. Although these stomata have primarily been studied in experimental mammals, little is known concerning the presence and properties of lymphatic stomata in the adult human pleura. Thus, adult human pleurae were examined for the presence or absence of lymphatic stomata. METHODS AND RESULTS: A total of 26 pulmonary ligaments (13 left and 13 right) were obtained from 15 adult human autopsy cases and examined using electron and light microscopy. The microscopic studies revealed the presence of apertures fringed with D2-40-positive, CD31-positive, and cytokeratin-negative endothelial cells directly communicating with submesothelial lymphatics in all of the pulmonary ligaments. The apertures' sizes and densities varied from case to case according to the serial tissue section. The medians of these aperture sizes ranged from 2.25 to 8.75 µm in the left pulmonary ligaments and from 2.50 to 12.50 µm in the right pulmonary ligaments. The densities of the apertures ranged from 2 to 9 per mm(2) in the left pulmonary ligaments and from 2 to 18 per mm(2) in the right pulmonary ligaments. However, no significant differences were found regarding the aperture size (p=0.359) and density (p=0.438) between the left and the right pulmonary ligaments. CONCLUSIONS: Our study revealed that apertures exhibit structural adequacy as lymphatic stomata on the surface of the pulmonary ligament, thereby providing evidence that lymphatic stomata are present in the adult human pleura.
[Mh] Termos MeSH primário: Ligamentos/anatomia & histologia
Pulmão/anatomia & histologia
Estomas Peritoneais/anatomia & histologia
[Mh] Termos MeSH secundário: Adulto
Idoso
Idoso de 80 Anos ou mais
Autopsia
Feminino
Seres Humanos
Ligamentos/citologia
Ligamentos/ultraestrutura
Pulmão/citologia
Pulmão/ultraestrutura
Masculino
Meia-Idade
Estomas Peritoneais/citologia
Estomas Peritoneais/ultraestrutura
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1603
[Cu] Atualização por classe:160601
[Lr] Data última revisão:
160601
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:141220
[St] Status:MEDLINE
[do] DOI:10.1089/lrb.2014.0009


  5 / 12 MEDLINE  
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[PMID]:23931068
[Au] Autor:Wang J; Ping Z; Jiang T; Yu H; Wang C; Chen Z; Zhang X; Xu D; Wang L; Li Z; Li JC
[Ad] Endereço:Institute of Cell Biology, Zhejiang University, 866 Yuhangtang Road, Hangzhou 310058, China.
[Ti] Título:Ultrastructure of lymphatic stomata in the tunica vaginalis of humans.
[So] Source:Microsc Microanal;19(6):1405-9, 2013 Dec.
[Is] ISSN:1435-8115
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Lymphatic stomata are small openings of lymphatic capillaries on the surface of the mesothelium that lines the serous cavity and have the function of active absorption. They play an important role in physiological and pathological conditions. The cavity of the tunica vaginalis is a typical serous cavity of the testis, but the lymphatic stomata of the tunica vaginalis of humans have never been reported. Here, we studied their ultrastructure by scanning and transmission electron microscopy. The submesothelial connective tissue with foramina was investigated after the mesothelial cells were digested using NaOH solution. We found the lymphatic stomata in cuboidal mesothelial cell regions of the parietal layer of the tunica vaginalis of humans with a diameter of about 1-2 µm. Sometimes, closed lymphatic stomata could be observed. Our study is the first to report the existence of lymphatic stomata of the tunica vaginalis of humans. We found that the tunica vaginalis cavity is connected with the lymphatic system through the stomata, which might provide a morphological basis for the drainage of hydrocele and tumor metastasis of the tunica vaginalis of humans.
[Mh] Termos MeSH primário: Estomas Peritoneais/ultraestrutura
Peritônio/ultraestrutura
Testículo/ultraestrutura
[Mh] Termos MeSH secundário: Seres Humanos
Masculino
Microscopia Eletrônica de Varredura
Microscopia Eletrônica de Transmissão
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1406
[Cu] Atualização por classe:131115
[Lr] Data última revisão:
131115
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:130813
[St] Status:MEDLINE
[do] DOI:10.1017/S1431927613012713


  6 / 12 MEDLINE  
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[PMID]:21502833
[Au] Autor:Iyer VB; McKiernan PJ; Foster K; Gupte GL
[Ti] Título:Stomal varices manifestation of portal hypertension in advanced intestinal failure-associated liver disease.
[So] Source:J Pediatr Gastroenterol Nutr;52(5):630-1, 2011 May.
[Is] ISSN:1536-4801
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Hipertensão Portal/complicações
Enteropatias/complicações
Hepatopatias/etiologia
Síndrome do Intestino Curto/complicações
Varizes/etiologia
[Mh] Termos MeSH secundário: Varizes Esofágicas e Gástricas/diagnóstico por imagem
Feminino
Seres Humanos
Lactente
Intestino Delgado/transplante
Transplante de Fígado
Estomas Peritoneais/irrigação sanguínea
Ultrassonografia
[Pt] Tipo de publicação:CASE REPORTS; LETTER
[Em] Mês de entrada:1112
[Cu] Atualização por classe:161125
[Lr] Data última revisão:
161125
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:110420
[St] Status:MEDLINE
[do] DOI:10.1097/MPG.0b013e3182042917


  7 / 12 MEDLINE  
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[PMID]:20186966
[Au] Autor:Wang ZB; Li M; Li JC
[Ad] Endereço:Institute of Cell Biology, Zhejiang University School of Medicine, Hangzhou, China.
[Ti] Título:Recent advances in the research of lymphatic stomata.
[So] Source:Anat Rec (Hoboken);293(5):754-61, 2010 May.
[Is] ISSN:1932-8494
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Lymphatic stomata are small openings of lymphatic capillaries on the free surface of the mesothelium. The peritoneal cavity, pleural cavity, and pericardial cavity are connected with lymphatic system via these small openings, which have the function of active absorption. The ultrastructure of the lymphatic stomata and their absorption from the body cavities are important clinically, such as ascites elimination, neoplasm metastasis, and inflammatory reaction. The lymphatic stomata play an important role in the physiological and pathological conditions. Our previous study indicated for the first time that nitric oxide (NO) could regulate the opening and absorption of the lymphatic stomata. It could decrease the level of free intracellular calcium [Ca(2+)] through increasing the cyclic guanosine monophosphate (cGMP) level in the rat peritoneal mesothelial cells, thus regulating the lymphatic stomata. This process is related with the NO-cGMP-[Ca(2+)] signal pathway. In this review, we summarize the recent advances in understanding the development and the function of the lymphatic stomata. The ultrastructure and regulations of the lymphatic stomata are also discussed in this review.
[Mh] Termos MeSH primário: Vasos Linfáticos/fisiologia
Vasos Linfáticos/ultraestrutura
Estomas Peritoneais/fisiologia
Estomas Peritoneais/ultraestrutura
Peritônio/fisiologia
Peritônio/ultraestrutura
[Mh] Termos MeSH secundário: Animais
Sinalização do Cálcio/fisiologia
GMP Cíclico/metabolismo
Epitélio/fisiologia
Epitélio/ultraestrutura
Seres Humanos
Linfa/fisiologia
Óxido Nítrico/metabolismo
Cavidade Peritoneal/anatomia & histologia
Cavidade Peritoneal/fisiologia
Ratos
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
31C4KY9ESH (Nitric Oxide); H2D2X058MU (Cyclic GMP)
[Em] Mês de entrada:1008
[Cu] Atualização por classe:131121
[Lr] Data última revisão:
131121
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:100227
[St] Status:MEDLINE
[do] DOI:10.1002/ar.21101


  8 / 12 MEDLINE  
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[PMID]:18213706
[Au] Autor:Li YY; Li JC
[Ad] Endereço:Institute of Cell Biology, Zhejiang University, Hangzhou, PR China.
[Ti] Título:Cell signal transduction mechanism for nitric oxide regulating lymphatic stomata and its draining capability.
[So] Source:Anat Rec (Hoboken);291(2):216-23, 2008 Feb.
[Is] ISSN:1932-8486
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:We have previously demonstrated that nitric oxide (NO) is involved in the regulation of the lymphatic stomata. However, the related mechanisms are still unknown. The present study was designed to test the hypothesis that NO-cyclic guanosine monophosphate (cGMP) -mediated cytosolic Ca(2+) concentration ([Ca(2+)]i) signaling may contribute to the regulation of the lymphatic stomata and lymph drainage. Using trypan blue as a tracer, the effects of NO-cGMP-Ca(2+) signal cascade on the lymphatic stomata and lymph absorption were examined by means of scanning electron microscopy. Then, the role of NO in cGMP and [Ca(2+)]i of rat peritoneal mesothelial cells (RPMCs) was measured by radioimmunoassay and a confocal laser scanning microscope. Our results showed that NO-donor spermine/nitric oxide complex (Sper/NO) could broaden the opening area of the lymphatic stomata and enhance lymph absorption in a dose-dependent manner. These NO-mediated changes could be blocked by 1H-[1,2,4] oxadiazolo [4,3-a] quinoxalin-1-one (ODQ), a specific inhibitor of soluble guanylyl cyclase, and mimicked by calcium channel blocker nifedipine. Furthermore, Sper/NO enhanced the cGMP level and lessened [Ca(2+)](i) in RPMCs, which was completely abrogated at the presence of ODQ. Nifedipine induced an immediate and marked decrease of [Ca(2+)](i) in the RPMCs, which was not attenuated by addition of Sper/NO, indicating that the Sper/NO-cGMP signaling system induced [Ca(2+)](i) change was related to the L-type voltage-gated calcium channel in the RPMCs. Our results suggest that NO enlarges the opening area of the lymphatic stomata to strengthen the lymph drainage of tracer by means of NO-cGMP-[Ca(2+)]i signal transduction pathway in the RPMCs.
[Mh] Termos MeSH primário: Sinalização do Cálcio/fisiologia
GMP Cíclico/metabolismo
Óxido Nítrico/metabolismo
Estomas Peritoneais/metabolismo
[Mh] Termos MeSH secundário: Animais
Diafragma/fisiologia
Linfa/fisiologia
Masculino
Estomas Peritoneais/ultraestrutura
Ratos
Ratos Sprague-Dawley
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
31C4KY9ESH (Nitric Oxide); H2D2X058MU (Cyclic GMP)
[Em] Mês de entrada:0804
[Cu] Atualização por classe:131121
[Lr] Data última revisão:
131121
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:080124
[St] Status:MEDLINE
[do] DOI:10.1002/ar.20638


  9 / 12 MEDLINE  
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[PMID]:15719135
[Au] Autor:Li YY; Li JC
[Ad] Endereço:Department of Lymphology, Institute of Cell Biology, Zhejiang University, Hangzhou 310031, China.
[Ti] Título:[Effects of nitric oxide on peritoneal lymphatic stomata and lymph drainage via NO-cGMP-Ca2+ pathway].
[So] Source:Sheng Li Xue Bao;57(1):45-53, 2005 Feb 25.
[Is] ISSN:0371-0874
[Cp] País de publicação:China
[La] Idioma:chi
[Ab] Resumo:To study the cell signal transduction mechanism of nitric oxide (NO) on the peritoneal lymphatic stomata and lymph drainage in the rat, cGMP content were measured by a commercially available radioimmunoassay kit, and the [Ca(2+)](i) were observed by a confocal laser scanning microscope in the cultured peritoneal mesothelial cell. Animal experiment was practiced to study the effect of NO-cGMP-Ca(2+) pathway on the lymphatic stomata and lymph absorption. The results showed that: (1) Sper/NO increased cGMP of the rat peritoneal mesothelial cell (RPMC) in a dose-dependent manner (P<0.01) compared to the control group. This effect was blocked by 1H-[1,2,4] oxadiazolo [4,3-a] quinoxalin-1-one (ODQ) (P<0.05), a specific inhibitor of soluble guanylyl cyclase (sGC). The level of [Ca(2+)](i) in single RPMC decreased by adding Sper/NO (P<0.05). Pretreatment with ODQ for 10 min blocked the Sper/NO-induced decrease in [Ca(2+)](i). L-typed calcium channel blocker nifedipine induced an immediate and marked decrease in [Ca(2+)](i) (P<0.05).. After [Ca(2+)](i) reached a balance again, adding Sper/NO could not change [Ca(2+)](i) (P>0.05). (2) Sper/NO increased the area of the stomata (P<0.01) and the quantity of the tracer in a dose-dependent manner (P<0.05) compared to the control group. Pretreatment with ODQ significantly inhibited Sper/NO-induced change of lymphatic stomata and lymph drainage (P<0.01). Nifedipine increased the opening area of the lymphatic stomata (P< 0.01) and the concentration of absorbed trypan blue of the diaphragm (P<0.05). Sper/NO could not make a further change in the samples pretreated by nifedipine (P> 0.05). The results indicate that NO can decrease [Ca(2+)](i) in the RPMC through the NO-cGMP pathway. This procession is related with the L- type voltage-gated Ca(2+) channel. NO enlarges the opening area of the lymphatic stomata and enhances the lymph drainage of tracer by NO-cGMP-[Ca(2+)](i) pathway.
[Mh] Termos MeSH primário: Sinalização do Cálcio/fisiologia
GMP Cíclico/metabolismo
Linfa/fisiologia
Óxido Nítrico/fisiologia
Estomas Peritoneais/fisiologia
[Mh] Termos MeSH secundário: Animais
Feminino
Vasos Linfáticos/fisiologia
Masculino
Distribuição Aleatória
Ratos
Ratos Sprague-Dawley
[Pt] Tipo de publicação:ENGLISH ABSTRACT; JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
31C4KY9ESH (Nitric Oxide); H2D2X058MU (Cyclic GMP)
[Em] Mês de entrada:1206
[Cu] Atualização por classe:131121
[Lr] Data última revisão:
131121
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:050219
[St] Status:MEDLINE


  10 / 12 MEDLINE  
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[PMID]:15450484
[Au] Autor:Bodega F; Agostoni E
[Ad] Endereço:Istituto di Fisiologia Umana I, Università di Milano, Via Mangiagalli 32, 20133 Milano, Italy.
[Ti] Título:Contribution of lymphatic drainage through stomata to albumin removal from pleural space.
[So] Source:Respir Physiol Neurobiol;142(2-3):251-63, 2004 Sep 15.
[Is] ISSN:1569-9048
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:The contribution of lymphatic drainage through the stomata of parietal mesothelium to the overall removal of labeled albumin from the pleural space was found 89% in sheep with very large hydrothoraces (10 ml/kg), a condition involving a approximately 20 times increase in lymphatic drainage [Broaddus et al., J. Appl. Physiol. 64 (1988) 384]. We determined this contribution in anesthetized rabbits with small (0.12 ml/kg) and large (2.4 ml/kg) hydrothoraces of Ringer-albumin with labeled albumin and labeled dextran-2000 kDa. This dextran was used as marker of liquid removal through the stomata because it should essentially leave the pleural space through the stomata only, owing to its size. The removal of labeled albumin by lymphatic drainage through the stomata was 39% of the overall removal in the small hydrothoraces, and 64% in the large ones. Hence, lymphatic drainage through the stomata does not contribute most of protein and liquid removal from the pleural space under physiological conditions, as it has been maintained. It markedly increases with the increase in pleural liquid volume.
[Mh] Termos MeSH primário: Albuminas/metabolismo
Drenagem
Vasos Linfáticos/metabolismo
Estomas Peritoneais/fisiologia
Cavidade Pleural/metabolismo
[Mh] Termos MeSH secundário: Animais
Dextranos/metabolismo
Fluorescamina
Lateralidade Funcional/fisiologia
Frequência Cardíaca/fisiologia
Hidrotórax/metabolismo
Coelhos
Ventilação
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Albumins); 0 (Dextrans); 38183-12-9 (Fluorescamine)
[Em] Mês de entrada:0412
[Cu] Atualização por classe:161124
[Lr] Data última revisão:
161124
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:040929
[St] Status:MEDLINE



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