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[PMID]:29400035
[Au] Autor:Clerico C; Dumas P; Fernandez J; Chignon-Sicard B
[Ti] Título:[Face and neck lift using a superficial musculo-aponeuro­t­ic system (SMAS) plication: Radiological analysis of tissu displacement, a case report].
[So] Source:Rev Laryngol Otol Rhinol (Bord);136(4):143-7, 2015.
[Is] ISSN:0035-1334
[Cp] País de publicação:France
[La] Idioma:fre
[Ab] Resumo:Objectives: Face and neck lift (FNL) using SMAS plication is a simple and well-known surgical technique. The principle of smas plication from two fixed points allows an important tissue ascension. Our purpose was to objectively evaluate the SMAS plication results, although a common critic may be due to its early deep tissular displacement. Materials and methods: We present the case of a 65 y.o. female patient who received a FNL. Miniature metal pins were placed on the external surface of the SMAS in order to ensure radiological monitoring. A cephalo­metric and photographic monitoring were performed pre­operatively and on day 1, months 2, 6 and 16 postoperatively . We performed a computed numerised analysis of the movement of the markers in an orthogonal axis. Results: All our bearings kept a constant position in the radiographic follow-up , demons­tra­ting the fixity of SMAS kinked 16 months postoperatively. Clinically the correction remained a good appearance with a very slight relaxation of the superficial tissues (skin and subcutaneous fat). Conclusion: In the case of our patient, the tensioning of the deep facial plan (the SMAS) objectively appeared to be efficient over time, with an overall delay of 16 months. Our protocole appeared to be coherent without any specific complication. It permits to objectively differentiate the relaxation of the deep or superfial tissues after a facial lift procedure.
[Mh] Termos MeSH primário: Músculos Faciais/cirurgia
Ritidoplastia/métodos
[Mh] Termos MeSH secundário: Idoso
Feminino
Seres Humanos
Rejuvenescimento
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180308
[Lr] Data última revisão:
180308
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180206
[St] Status:MEDLINE


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[PMID]:29211113
[Au] Autor:Felício CM; Lima MDRF; Medeiros APM; Ferreira JTL
[Ad] Endereço:Departamento de Oftalmologia, Otorrinolaringologia e Cirurgia de Cabeça e Pescoço, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo - USP - Ribeirão Preto (SP), Brazil.
[Ti] Título:Orofacial Myofunctional Evaluation Protocol for older people: validity, psychometric properties, and association with oral health and age.
[So] Source:Codas;29(6):e20170042, 2017 Dec 04.
[Is] ISSN:2317-1782
[Cp] País de publicação:Brazil
[La] Idioma:eng
[Ab] Resumo:PURPOSE: To develop a comprehensive assessment protocol for identifying, classifying and grading changes in stomatognathic system components and functions of older people, to determine its psychometric properties and verify its association with oral health and age. METHODS: The content validity of the Orofacial Myofunctional Evaluation with Scores for Elders protocol (OMES-Elders) was established based on the literature. The protocol contains three domains: appearance/posture, mobility, and functions of the stomatognathic system. Eighty-two healthy elder volunteers (mean age 69±7.24 years) were evaluated using the OMES-Elders. A test-screening for orofacial disorders (reference) was used to analyze the concurrent validity (correlation test), sensitivity, specificity and accuracy (Receiver Operating Characteristic Curve: ROC curve) of the OMES-Elders. The association of the OMES-Elders scores with the Oral Health Index (OHX) and age in the sample was tested. RESULTS: There was a significant correlation between the OMES-Elders and the reference test (p < 0.001). Reliability coefficients ranged from good (0.89) to excellent (0.99). The OMES-Elders protocol had a sensitivity of 82.9%, specificity of 83.3% and accuracy of 0.83. The scores of the protocol were significantly lower in individuals with worse oral health (OHX ≤ 61%), although individuals with adequate oral health (OHX ≥ 90%) also had myofunctional impairments. The predictors OHX and age explained, respectively, 33% and 30% of the variance in the OMES-Elders total score. CONCLUSION: As the first specific orofacial myofunctional evaluation of older people, the OMES-Elders protocol proved to be valid, reliable and its total score was associated with oral health and age.
[Mh] Termos MeSH primário: Protocolos Clínicos
Transtornos de Deglutição/diagnóstico
Transtornos dos Movimentos/diagnóstico
[Mh] Termos MeSH secundário: Fatores Etários
Idoso
Idoso de 80 Anos ou mais
Músculos Faciais/fisiopatologia
Feminino
Seres Humanos
Masculino
Meia-Idade
Terapia Miofuncional
Saúde Bucal
Psicometria
Reprodutibilidade dos Testes
Sensibilidade e Especificidade
[Pt] Tipo de publicação:EVALUATION STUDIES; JOURNAL ARTICLE
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180131
[Lr] Data última revisão:
180131
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171207
[St] Status:MEDLINE


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[PMID]:29245240
[Au] Autor:Chen B; Lu H; Ren C; Ma L; Hu X; Qi H; Gao Z
[Ad] Endereço:Department of Plastic Surgery, China Japan Friendship Hospital, Beijing, China.
[Ti] Título:Excision of sebaceous cyst by intraoral approach: A case report.
[So] Source:Medicine (Baltimore);96(49):e8803, 2017 Dec.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:RATIONALE: Surgical removal of a sebaceous cyst is usually accomplished through an external incision, which inevitably results in a scar. Herein, we described an intraoral approach for excising sebaceous cysts located in the lip or cheek near lip commissure, to avoid a skin scar. PATIENT CONCERNS: Removal of the cyst but without leaving a scar on the face. DIAGNOSES: Six patients were diagnosed with a subcutaneous cyst located in the lip or cheek near lip commissure. INTERVENTIONS: We implemented an intraoral approach to excise the cyst, wherein an intraoral incision was made and blunt dissection was performed through the buccinator muscle or orbicularis oris muscle until the cyst wall was seen. The cyst was then dissected from the surrounding subcutaneous tissue by careful blunt dissection with a hemostat and completely removed through the intraoral incision. OUTCOMES: All patients had complete recovery, with no recurrence or complaints for at least 6 months after the surgery. LESSONS: A sebaceous cyst located in the lip or cheek near lip commissure can be excised by an intraoral approach through the mouth, which avoids a visible scar on the skin.
[Mh] Termos MeSH primário: Bochecha/cirurgia
Dissecação/métodos
Cisto Epidérmico/cirurgia
Músculos Faciais/cirurgia
Lábio/cirurgia
[Mh] Termos MeSH secundário: Adulto
Cicatriz/etiologia
Cicatriz/prevenção & controle
Dissecação/efeitos adversos
Feminino
Seres Humanos
Masculino
Meia-Idade
Estudos Retrospectivos
Resultado do Tratamento
Adulto Jovem
[Pt] Tipo de publicação:EVALUATION STUDIES; JOURNAL ARTICLE
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171222
[Lr] Data última revisão:
171222
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:171217
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000008803


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[PMID]:28739170
[Au] Autor:Denadai R; Sabbag A; Raposo-Amaral CE; Filho JCP; Nagae MH; Raposo-Amaral CA
[Ad] Endereço:Institute of Plastic and Craniofacial Surgery, SOBRAPAR Hospital, Campinas, São Paulo, Brazil.
[Ti] Título:Bilateral buccinator myomucosal flap outcomes in nonsyndromic patients with repaired cleft palate and velopharyngeal insufficiency.
[So] Source:J Plast Reconstr Aesthet Surg;70(11):1598-1607, 2017 Nov.
[Is] ISSN:1878-0539
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: The purpose of this study was to assess speech outcomes and complication rate in nonsyndromic repaired cleft palate patients undergoing bilateral buccinator myomucosal flaps for velopharyngeal insufficiency management. METHODS: A prospective study of consecutive repaired cleft palate patients with velopharyngeal insufficiency who underwent bilateral buccinator myomucosal flaps was conducted. Three experienced evaluators performed a blinded perceptual speech evaluation (hypernasality, audible nasal emission, and intraoral pressure). Successful speech outcome was defined as normal or borderline sufficient velopharyngeal function at 15 months postoperatively. Obstructive sleep apnea screening tools were applied preoperatively and postoperatively. Complication rate was also collected. RESULTS: Fifty-three patients were included. There were 11 (21%) surgical complications, with no complete flap loss, snoring, sleep disturbance, and/or mouth breathing. All patients presented low pre- and postoperative risk for obstructive sleep apnea. At 15 months postoperatively, hypernasality (0.4 ± 0.6), audible nasal emissions (0.2 ± 0.4), and intraoral pressure (0.1 ± 0.3) were significantly (all p < 0.05) lower than preoperative measurements (hypernasality: 2.7 ± 0.5; audible nasal emissions: 2.2 ± 0.8; and intraoral pressure: 0.9 ± 0.3). Forty-five (85%) patients presented successful speech outcome. CONCLUSION: The bilateral buccinator myomucosal flap is an effective and safe surgical strategy for the management of persistent velopharyngeal insufficiency.
[Mh] Termos MeSH primário: Fissura Palatina/cirurgia
Músculos Faciais/transplante
Mucosa Bucal/transplante
Procedimentos Cirúrgicos Reconstrutivos/métodos
Fala/fisiologia
Retalhos Cirúrgicos
Insuficiência Velofaríngea/cirurgia
[Mh] Termos MeSH secundário: Criança
Pré-Escolar
Feminino
Seguimentos
Seres Humanos
Masculino
Estudos Prospectivos
Resultado do Tratamento
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171102
[Lr] Data última revisão:
171102
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170726
[St] Status:MEDLINE


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[PMID]:28712884
[Au] Autor:Berchtold V; Stofferin H; Moriggl B; Brenner E; Pauzenberger R; Konschake M
[Ad] Endereço:Division of Clinical and Functional Anatomy, Department for Anatomy, Histology and Embryology, Medical University of Innsbruck (MUI), Austria.
[Ti] Título:The supraorbital region revisited: An anatomic exploration of the neuro-vascular bundle with regard to frontal migraine headache.
[So] Source:J Plast Reconstr Aesthet Surg;70(9):1171-1180, 2017 Sep.
[Is] ISSN:1878-0539
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Recent findings on the pathogenesis of frontal migraine headache support, besides a central vasogenic cause, an alternative peripheral mechanism involving compressed craniofacial nerves. This is further supported by the efficiency of botulinum toxin injections as a new treatment option in frontal migraine headache patients. METHODS: The supraorbital regions of 22 alcohol-glycerine-embalmed facial halves of both sexes were dissected. Both the supratrochlear and supraorbital nerves (STN and SON, respectively) were identified, and their relationship with the corrugator supercilii muscle (CSM) was investigated by dissection and ultrasound. The course of both nerves was defined, and the interaction between the supraorbital artery (SOA) and SON was determined. RESULTS: We discovered a new possible compression point of the STN passing through the orbital septum and verified previously described compression points of both STN and SON. Osteofibrous channels used by the STN and SON were found constantly. We described the varying topography of the STN and CSM, the SON and CSM, and the SON and SOA. Further, we provide an algorithm for the ultrasound visualization of the supraorbital neurovascular bundle. CONCLUSION: Our data support the hypothesis of a peripheral mechanism for frontal migraine headache because of following potential irritation points: first, the CSM is constantly perforated by the SON and frequently by the STN; second, the topographic proximity between SOA and SON and the osteofibrous channels is used by the SON and STN; and third, the STN passes through the orbital septum.
[Mh] Termos MeSH primário: Face/irrigação sanguínea
Face/inervação
Músculos Faciais/anatomia & histologia
Nervo Troclear/anatomia & histologia
[Mh] Termos MeSH secundário: Adulto
Idoso
Idoso de 80 Anos ou mais
Artérias
Cadáver
Feminino
Seres Humanos
Masculino
Meia-Idade
Transtornos de Enxaqueca/etiologia
Órbita
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170914
[Lr] Data última revisão:
170914
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170718
[St] Status:MEDLINE


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[PMID]:28688864
[Au] Autor:Neville C; Venables V; Aslet M; Nduka C; Kannan R
[Ad] Endereço:Queen Victoria Hospital, Holtye Road, East Grinstead, West Sussex RH19 3DZ, UK. Electronic address: trina_curtis@hotmail.co.uk.
[Ti] Título:An objective assessment of botulinum toxin type A injection in the treatment of post-facial palsy synkinesis and hyperkinesis using the synkinesis assessment questionnaire.
[So] Source:J Plast Reconstr Aesthet Surg;70(11):1624-1628, 2017 Nov.
[Is] ISSN:1878-0539
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:This study aimed to provide reliable and valid evidence that botulinum toxin type A (BTX-A) is a successful treatment for facial synkinesis in facial palsy by using the synkinesis assessment questionnaire (SAQ) tool. Fifty-one patients completed questionnaires pre- and post-BTX-A treatment over 103 cycles of treatment. Each patient was individually assessed and then treated according to their presenting symptoms with a dosage in each injection site of between 0.5 and 5 U of BTX-A. A two-tailed paired samples t-test was used to compare the scores for each question before and after treatment. A significant difference was found between all scores before and after treatment at the level of p < 0.05. There was not only an improvement in the mean score in the post-treatment group but also a smaller spread of scores in the post-treatment group than in the pre-treatment group. The study showed that SAQ scores decreased significantly for every question on the SAQ after treatment. This indicates that BTX-A is an effective treatment for synkinesis, adding further weight to current evidence. The study also indicated that BTX-A continues to be effective even after three rounds of treatment, with a significant decrease in overall scores after each treatment cycle.
[Mh] Termos MeSH primário: Toxinas Botulínicas Tipo A/administração & dosagem
Paralisia Facial/complicações
Inquéritos e Questionários
Sincinesia/tratamento farmacológico
[Mh] Termos MeSH secundário: Músculos Faciais
Paralisia Facial/tratamento farmacológico
Feminino
Seres Humanos
Injeções Intramusculares
Masculino
Fármacos Neuromusculares/administração & dosagem
Sincinesia/etiologia
Resultado do Tratamento
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Neuromuscular Agents); EC 3.4.24.69 (Botulinum Toxins, Type A)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171102
[Lr] Data última revisão:
171102
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170710
[St] Status:MEDLINE


  7 / 6812 MEDLINE  
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[PMID]:28661994
[Au] Autor:Bertucci V
[Ad] Endereço:Division of Dermatology University of Toronto, Toronto, Canada.
[Ti] Título:Commentary on The Facial Platysma and Its Underappreciated Role in Lower Face Dynamics and Contour.
[So] Source:Dermatol Surg;43(8):1050-1052, 2017 08.
[Is] ISSN:1524-4725
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Músculos Faciais/cirurgia
Músculos do Pescoço/cirurgia
[Mh] Termos MeSH secundário: Face
Seres Humanos
[Pt] Tipo de publicação:JOURNAL ARTICLE; COMMENT
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171011
[Lr] Data última revisão:
171011
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170630
[St] Status:MEDLINE
[do] DOI:10.1097/DSS.0000000000001214


  8 / 6812 MEDLINE  
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Texto completo SciELO Brasil
[PMID]:28591280
[Au] Autor:Renesto ADC; Osaki TH; Osaki MH; Hirai FE; Campos M
[Ad] Endereço:Department of Ophthalmology and Visual Sciences, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP), São Paulo, SP, Brazil.
[Ti] Título:Keratoconus progression is not inhibited by reducing eyelid muscular force with botulinum toxin A treatment: a randomized trial.
[So] Source:Arq Bras Oftalmol;80(2):88-92, 2017 Mar-Apr.
[Is] ISSN:1678-2925
[Cp] País de publicação:Brazil
[La] Idioma:eng
[Ab] Resumo:Purpose:: To evaluate whether reducing eyelid muscular force through the administration of botulinum toxin type A (BTX-A) to the orbicularis oculi muscles of patients with keratoconus affected corneal parameters indicative of disease progression. Methods:: In this prospective parallel randomized clinical trial, 40 eyes of 40 patients with keratoconus were randomized into equally sized control and BTX-A groups. Patients in the BTX-A group received subcutaneous BTX-A injections into the orbicularis muscle. The control group received no intervention. Palpebral fissure height, best spectacle-corrected visual acuity (BSCVA), and corneal topographic parameters were evaluated at baseline and at 3-, 6-, 12-, and 18-month follow-ups. Results:: The mean ± standard deviation vertical palpebral fissure heights were 9.74 ± 1.87 mm and 9.45 ± 1.47 mm at baseline in the control and BTX-A groups, respectively, and 10.0 ± 1.49 mm and 9.62 ± 1.73 mm at 18 months, with no significant difference between the groups (p=0.337). BSCVA values were 0.63 ± 0.56 and 0.60 ± 0.27 at baseline in the control and BTX-A groups (p=0.643), and 0.52 ± 0.59 and 0.45 ± 0.26 at 18 months, again with no significant difference between the groups (p=0.452). In addition, there were no statistical differences between the groups at 18 months for the three keratometry topographic parameters: flattest (K1), steepest (K2), and mean (Km) keratometry (p=0.562). Conclusion:: BTX-A inhibition of eyelid force generation did not result in detectable changes in corneal parameters in keratoconic patients during 18 months of follow-up.
[Mh] Termos MeSH primário: Toxinas Botulínicas Tipo A/uso terapêutico
Progressão da Doença
Pálpebras/fisiopatologia
Ceratocone/tratamento farmacológico
Fármacos Neuromusculares/uso terapêutico
[Mh] Termos MeSH secundário: Adolescente
Adulto
Toxinas Botulínicas Tipo A/administração & dosagem
Protocolos Clínicos
Paquimetria Corneana
Topografia da Córnea
Pálpebras/efeitos dos fármacos
Músculos Faciais/efeitos dos fármacos
Feminino
Seres Humanos
Injeções Subcutâneas
Ceratocone/fisiopatologia
Masculino
Fármacos Neuromusculares/administração & dosagem
Estudos Prospectivos
Acuidade Visual
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
[Nm] Nome de substância:
0 (Neuromuscular Agents); EC 3.4.24.69 (Botulinum Toxins, Type A)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170927
[Lr] Data última revisão:
170927
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170608
[Cl] Clinical Trial:ClinicalTrial
[St] Status:MEDLINE


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[PMID]:28531312
[Au] Autor:Armstrong JE; Laing DG; Jinks AL
[Ad] Endereço:Faculty of Medicine, School of Women and Children's Health, University of New South Wales, Level 3, Sydney Children's Hospital, High Street, Randwick, New South Wales 2031, Australia and.
[Ti] Título:Taste-Elicited Activity in Facial Muscle Regions in 5-8-Week-Old Infants.
[So] Source:Chem Senses;42(5):443-453, 2017 Jun 01.
[Is] ISSN:1464-3553
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:The state of development of the sense of taste in humans during the first few months of life is only partially understood. Since taste plays a critical role in the feeding and nutrition of infants a better understanding of taste development during early life is required. Currently, information about the sense of taste in pre-verbal infants is obtained by analysis of videotaped facial expressions using the Baby FACS coding system. A potentially more objective faster procedure for assessing facial expressions not investigated in infants is electromyography (EMG). The method has been successfully used to study taste-elicited responses in the mid-face muscle regions of the levator labii and zygomaticus major of 6-9-year-olds and in a range of facial muscle regions in adults. Accordingly, this study aimed to investigate taste in young infants using EMG to 1) measure activity simultaneously in 4 facial muscle regions in response to 3 common tastants and 2) determine whether the activities of one or more muscle regions is needed to provide evidence of perception of a tastant by an infant. The results indicated that multiple facial muscle regions responded simultaneously but differentially to non-sweet and sweet tastants and recordings of activities from 3 or 4 regions simultaneously indicated that almost 100% of infants responded to the unpleasant tastes of quinine and citric acid, and 80% to sucrose.
[Mh] Termos MeSH primário: Músculos Faciais/efeitos dos fármacos
Músculos Faciais/fisiologia
Paladar/efeitos dos fármacos
Paladar/fisiologia
[Mh] Termos MeSH secundário: Ácido Cítrico/administração & dosagem
Ácido Cítrico/farmacologia
Eletromiografia
Feminino
Seres Humanos
Lactente
Masculino
Quinina/administração & dosagem
Quinina/farmacologia
Sacarose/administração & dosagem
Sacarose/farmacologia
[Pt] Tipo de publicação:CONTROLLED CLINICAL TRIAL; JOURNAL ARTICLE
[Nm] Nome de substância:
2968PHW8QP (Citric Acid); 57-50-1 (Sucrose); A7V27PHC7A (Quinine)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170913
[Lr] Data última revisão:
170913
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170523
[St] Status:MEDLINE
[do] DOI:10.1093/chemse/bjx023


  10 / 6812 MEDLINE  
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[PMID]:28522038
[Au] Autor:Giordano CN; Matarasso SL; Ozog DM
[Ad] Endereço:Department of Dermatology, Henry Ford Hospital, Detroit, Michigan.
[Ti] Título:Injectable and topical neurotoxins in dermatology: Basic science, anatomy, and therapeutic agents.
[So] Source:J Am Acad Dermatol;76(6):1013-1024, 2017 Jun.
[Is] ISSN:1097-6787
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Botulinum toxin is a potentially deadly anaerobic bacterial toxin that acts by inhibiting release of acetylcholine at the neuromuscular junction, thereby inhibiting contraction of the exposed striated muscle. There are currently 4 botulinum toxin preparations approved by the US Food and Drug Administration (FDA): onabotulinumtoxin, abobotulinumtoxin, incobotulinumtoxin and rimabotulinumtoxin. While significant overlap exists, each product has unique properties and specifications, including dosing, diffusion, and storage. Extensive physician knowledge of facial anatomy, coupled with key differences of the various neurotoxin types, is essential for safe and successful treatments. The first article in this continuing medical education series reviews key characteristics of each neurotoxin, including new and upcoming agents, and provides an anatomic overview of the most commonly injected cosmetic sites.
[Mh] Termos MeSH primário: Toxinas Botulínicas/administração & dosagem
Neurotoxinas/administração & dosagem
[Mh] Termos MeSH secundário: Administração Tópica
Toxinas Botulínicas/uso terapêutico
Técnicas Cosméticas
Dermatologia/métodos
Músculos Faciais/anatomia & histologia
Seres Humanos
Injeções
Neurotoxinas/uso terapêutico
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Neurotoxins); EC 3.4.24.69 (Botulinum Toxins)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170726
[Lr] Data última revisão:
170726
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170520
[St] Status:MEDLINE



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