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  1 / 10981 MEDLINE  
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[PMID]:29364825
[Au] Autor:Strippoli J; Durand R; Schmittbuhl M; Voyer R; Rompré P; Nishio C
[Ad] Endereço:Private Practice of Orthodontics in Tassin-la-Demi-Lune, France.
[Ti] Título:Pain and quality of life in patients undergoing guided piezocorticision- assisted orthodontic treatment.
[So] Source:J Clin Orthod;51(12):792-799, 2017 Dec.
[Is] ISSN:0022-3875
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Ortodontia Corretiva
Dor/etiologia
Piezocirurgia
Qualidade de Vida
[Mh] Termos MeSH secundário: Adolescente
Adulto
Processo Alveolar/cirurgia
Feminino
Seres Humanos
Masculino
Escala Visual Analógica
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180308
[Lr] Data última revisão:
180308
[Sb] Subgrupo de revista:D
[Da] Data de entrada para processamento:180125
[St] Status:MEDLINE


  2 / 10981 MEDLINE  
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[PMID]:29203740
[Au] Autor:Kuroedova VD; Vyzhenko EE; Makarova AN; Galych LB; Chikor TA
[Ad] Endereço:Department Of Post-Graduate Education Of Orthodontists, Educational And Scientific Institute Of Post-Graduate Education, Higher State Educational Establishment Of Ukraine, "Ukrainian Medical Stomatological Academy", Poltava, Ukraine.
[Ti] Título:Optical density of upper jaw in patients with malocclusion.
[So] Source:Wiad Lek;70(5):913-916, 2017.
[Is] ISSN:0043-5147
[Cp] País de publicação:Poland
[La] Idioma:eng
[Ab] Resumo:INTRODUCTION: The growth and formation of facial skeleton is in interrelation with growth of cervical spine. Computer tomography plays an important role to examine and investigate the density of bony tissue resulting from total increase of osteopenic diseases and diseases of periodontal tissue. The aim of the paper is to compare indices of mineral density of bony tissue of the upper jaw and mineral density of the second cervical vertebra in patients with malocclusion. MATERIALS AND METHODS: 37 orthodontic patients were involved in the investigation. They were divided into three age groups depending on the period of formation of dentofacial system. Density measurement of bone of the second cervical vertebra was done and also density measurement of upper jaw in the area of alveolar process between central incisors, canines and the first premolar on the level of the middle of roots, in the area of the first molars under the level of bifurcation and in cusp was performed. RESULTS: Optical density of bone of the second cervical vertebra with age increases from 501±61,06 to 587,6±48,81. The densest area on the upper jaw is alveolar process between central incisors, which increases with age from 1045,14±59,81 to 1318±69,28. The least indices of optical density were determined in area of the cusp of the upper jaw: the first group presented 174,21±38,94, and the third one included 338,87±26,91. CONCLUSIONS: Densitometry of bony tissue with computer tomography is diagnostically informative and available method for investigation and it can be used for diagnostics of bony tissue condition and for evaluation of orthodontic treatment.
[Mh] Termos MeSH primário: Processo Alveolar/diagnóstico por imagem
Densidade Óssea/fisiologia
Vértebras Cervicais/diagnóstico por imagem
Má Oclusão/diagnóstico por imagem
[Mh] Termos MeSH secundário: Criança
Tomografia Computadorizada de Feixe Cônico
Oclusão Dentária
Feminino
Seres Humanos
Processamento de Imagem Assistida por Computador
Masculino
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180308
[Lr] Data última revisão:
180308
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171206
[St] Status:MEDLINE


  3 / 10981 MEDLINE  
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[PMID]:29203739
[Au] Autor:Berezniakova AI; Cheremisina VF
[Ad] Endereço:National Pharmaceutical University, Kharkov, Ukraine.
[Ti] Título:4 and 6 interleukin's action in the pathogenesis of periodontitis, gingivitis and dental alveolitis.
[So] Source:Wiad Lek;70(5):910-912, 2017.
[Is] ISSN:0043-5147
[Cp] País de publicação:Poland
[La] Idioma:eng
[Ab] Resumo:INTRODUCTION: The paper presents the results of studying the role of interleukins 4 and 6 in the pathogenesis of periodontal tissue diseases, specifically, in periodontitis, gingivitis and alveolitis. THE AIM: To study the nature of participation of IL-4 and IL-6 in the mechanisms of development of periodontitis, gingivitis and alveolitis. MATERIALS AND METHODS: Studies were carried out on 80 nonlinear male rats with a body weight of 200.0 to 220.0 g divided into four groups of 20 animals each. The serum level of cytokines was determined by an enzyme immunoassay on the Multiscane Biotech analyzer using test systems manufactured by Caltag laboratories (USA). Statistical processing of the obtained digital results was processed with the help of the program "Statistica 8.0". Indicators of the reliability of changes between the control and intact groups also used the Student's test and the Excel program. The confidence level was taken at p <0.05. RESULTS: As a result of our experiments, noticeable changes in the anti-inflammatory cytokine IL-4 were observed in rats with experimental periodontitis. The level of IL-4 cytokine in rats with alveolitis did not differ from control. The level of proinflammatory cytokine IL-6 from all groups of animals with periodontal disease differed from control only in rats with gingivitis, where it decreased by 74% and its level became less with alveolitis and periodontitis, since in these diseases the level of IL-6 was practically the same from the control (p <0,05). We also succeeded in revealing that at a low level of profibrogenic IL-6, there is not enough stimulation of collagen synthesis in the periodontal bone tissue. The increased level of IL-4 in a group of animals with gingivitis, on the contrary, indicates the realization of a pathological reaction of the organism. CONCLUSIONS: The change in the levels of pro- and anti-inflammatory interleukins, especially with gingivitis, indicates a decrease in the body's adaptive reserves and may affect the further dynamics of the inflammatory process in the periodontal tissues.
[Mh] Termos MeSH primário: Processo Alveolar/imunologia
Gengivite/imunologia
Interleucina-4/sangue
Interleucina-6/sangue
Doenças Periodontais/imunologia
[Mh] Termos MeSH secundário: Animais
Modelos Animais de Doenças
Técnicas Imunoenzimáticas
Masculino
Ratos
Ratos Wistar
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Interleukin-6); 207137-56-2 (Interleukin-4)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180308
[Lr] Data última revisão:
180308
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171206
[St] Status:MEDLINE


  4 / 10981 MEDLINE  
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[PMID]:29407504
[Au] Autor:Maino G; Turci Y; Arreghini A; Paoletto E; Siciliani G; Lombardo L
[Ad] Endereço:Postgraduate School of Orthodontics, University of Ferrara, Ferrara, Italy.
[Ti] Título:Skeletal and dentoalveolar effects of hybrid rapid palatal expansion and facemask treatment in growing skeletal Class III patients.
[So] Source:Am J Orthod Dentofacial Orthop;153(2):262-268, 2018 Feb.
[Is] ISSN:1097-6752
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:INTRODUCTION: The purpose of this study was to describe the skeletal and dentoalveolar changes in a group of growing skeletal Class III patients treated with hybrid rapid palatal expansion and facemask. METHODS: Twenty-eight growing patients with skeletal Class III malocclusion were treated using a rapid maxillary expander with hybrid anchorage according to the ALT-Ramec protocol (SKAR III; E.P.), followed by 4 months of facemask therapy. Palatal miniscrew placement was accomplished via digital planning and the construction of a high-precision, individualized surgical guide. Pretreatment and posttreatment cephalometric tracings were analyzed, comparing dental and skeletal measurements. RESULTS: Point A advanced by a mean of 3.4 mm with respect to the reference plane Vert-T. The mandibular plane rotated clockwise, improving the ANB (+3.41°) and the Wits appraisal (+4.92 mm). The maxillary molar had slight extrusion (0.42 mm) and mesialization (0.87 mm). CONCLUSIONS: The use of a hybrid-anchorage expander followed by 4 months of facemask treatment improves the skeletal Class III relationship with minimal dental effects, even in older patients (mean age, 11 years 4 months, ± 2.5 years).
[Mh] Termos MeSH primário: Processo Alveolar/patologia
Aparelhos de Tração Extrabucal
Arcada Osseodentária/patologia
Má Oclusão de Angle Classe III/terapia
Técnica de Expansão Palatina
[Mh] Termos MeSH secundário: Fatores Etários
Cefalometria
Criança
Terapia Combinada
Tomografia Computadorizada de Feixe Cônico
Feminino
Seres Humanos
Masculino
Má Oclusão de Angle Classe III/diagnóstico por imagem
Má Oclusão de Angle Classe III/patologia
Técnica de Expansão Palatina/instrumentação
Radiografia Dentária
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180213
[Lr] Data última revisão:
180213
[Sb] Subgrupo de revista:D; IM
[Da] Data de entrada para processamento:180207
[St] Status:MEDLINE


  5 / 10981 MEDLINE  
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[PMID]:28457420
[Au] Autor:Baldan RCF; Coracin FL; Lins L; Mello WR; Santos PS
[Ad] Endereço:Dental Commission, Brazilian Association of Organ Transplantation, São Paulo, Brazil. Electronic address: renato_baldan@yahoo.com.br.
[Ti] Título:Atrophic Maxilla Reconstruction With Fresh Frozen Allograft Bone, Titanium Mesh, and Platelet-Rich Fibrin: Case Report.
[So] Source:Transplant Proc;49(4):893-897, 2017 May.
[Is] ISSN:1873-2623
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The purpose of this article was to report the clinical and radiographic findings about a case of a man affected by severely atrophic maxilla to demonstrate the clinical proceedings associated with alveolar reconstruction destined for dental implant rehabilitation. The 3-dimensional augmentation of the alveolar ridge with the use of fresh-frozen bone graft, platelet-rich fibrin membrane, and titanium mesh suggests potential benefits to the development of the bone formation physiology. The treatment combination may result in an optimal prognosis and represents an option for reconstruction of bone defects. At 8 months after surgery, no evidence of complications was observed; the clinical examination and computerized tomographic scan revealed bone formation and installed implant stability.
[Mh] Termos MeSH primário: Aumento do Rebordo Alveolar/métodos
Transplante Ósseo/métodos
Implantação Dentária Endo-Óssea/métodos
Maxila/cirurgia
Doenças Maxilares/cirurgia
Fibrina Rica em Plaquetas
[Mh] Termos MeSH secundário: Idoso
Aloenxertos
Processo Alveolar/cirurgia
Atrofia/patologia
Atrofia/cirurgia
Implantes Dentários
Seres Humanos
Masculino
Maxila/patologia
Doenças Maxilares/patologia
Telas Cirúrgicas
Titânio
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Dental Implants); D1JT611TNE (Titanium)
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180102
[Lr] Data última revisão:
180102
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170502
[St] Status:MEDLINE


  6 / 10981 MEDLINE  
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[PMID]:29190785
[Au] Autor:McCormack SW; Witzel U; Watson PJ; Fagan MJ; Gröning F
[Ad] Endereço:Medical and Biological Engineering Research Group, School of Engineering and Computer Science, University of Hull, Hull, United Kingdom.
[Ti] Título:Inclusion of periodontal ligament fibres in mandibular finite element models leads to an increase in alveolar bone strains.
[So] Source:PLoS One;12(11):e0188707, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Alveolar bone remodelling is vital for the success of dental implants and orthodontic treatments. However, the underlying biomechanical mechanisms, in particular the function of the periodontal ligament (PDL) in bone loading and remodelling, are not well understood. The PDL is a soft fibrous connective tissue that joins the tooth root to the alveolar bone and plays a critical role in the transmission of loads from the tooth to the surrounding bone. However, due to its complex structure, small size and location within the tooth socket it is difficult to study in vivo. Finite element analysis (FEA) is an ideal tool with which to investigate the role of the PDL, however inclusion of the PDL in FE models is complex and time consuming, therefore consideration must be given to how it is included. The aim of this study was to investigate the effects of including the PDL and its fibrous structure in mandibular finite element models. A high-resolution model of a human molar region was created from micro-computed tomography scans. This is the first time that the fibrous structure of the PDL has been included in a model with realistic tooth and bone geometry. The results show that omission of the PDL creates a more rigid model, reducing the strains observed in the mandibular corpus which are of interest when considering mandibular functional morphology. How the PDL is modelled also affects the strains. The inclusion of PDL fibres alters the strains in the mandibular bone, increasing the strains in the tooth socket compared to PDL modelled without fibres. As strains in the alveolar bone are thought to play a key role in bone remodelling during orthodontic tooth movement, future FE analyses aimed at improving our understanding and management of orthodontic treatment should include the fibrous structure of the PDL.
[Mh] Termos MeSH primário: Processo Alveolar/patologia
Análise de Elementos Finitos
Ligamento Periodontal/anatomia & histologia
[Mh] Termos MeSH secundário: Fenômenos Biomecânicos
Seres Humanos
Microtomografia por Raio-X
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171226
[Lr] Data última revisão:
171226
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171201
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0188707


  7 / 10981 MEDLINE  
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[PMID]:29173863
[Au] Autor:Kula TJ; Ghoneima A; Eckert G; Parks ET; Utreja A; Kula K
[Ad] Endereço:Department of Orthodontics and Oral Facial Genetics, School of Dentistry, Indiana University, Indianapolis, Ind.
[Ti] Título:Two-dimensional vs 3-dimensional comparison of alveolar bone over maxillary incisors with A-point as a reference.
[So] Source:Am J Orthod Dentofacial Orthop;152(6):836-847.e2, 2017 Dec.
[Is] ISSN:1097-6752
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:INTRODUCTION: Our objectives were to compare, relative to A-point, (1) bone thickness over the most forward maxillary incisor (MFMI) in 2 dimensions vs 3 dimensions, and (2) bone thickness and inclination of each maxillary incisor in 3 dimensions. METHODS: Thirty-four cone-beam computed tomography (CBCT) images were coded, and 2-dimensional (2D) cephalograms were derived from each image using Dolphin software (Dolphin Imaging and Management Solutions, Chatsworth, Calif). A-point and the MFMI crown were located. After reliability tests, alveolar bone buccal to 3 points on the MFMI root, bone to reference line Frankfort horizontal (FH)-A-point, and incisor inclination were measured. This procedure was repeated on the 3-dimensional (3D) CBCT images comparing MFMI with all maxillary incisors. The 2D and 3D measurements were compared using paired t tests, and 3D measurements were compared with analysis of variance. A 5% significance level was used for all tests. RESULTS: The MFMI's buccal bone thickness at the root apices and the distance between buccal bone and FH-A-point line at 2 root points were significantly greater in 2 dimensions than in 3 dimensions. In 3 dimensions, bone thickness at MFMI's root apex and the distance from FH-A-point line at all root points were significantly greater than those of the lateral incisors. Bone buccal to MFMI was significantly smaller than at the lateral incisors 3 mm from the cementoenamel junction. CONCLUSIONS: Evaluation of 2D CBCT derivations can result in overestimation of alveolar bone buccal to the maxillary incisor root apices compared with 3D evaluations. The anterior nasal spine obscures bone measurements over the maxillary incisors in 2 dimensions.
[Mh] Termos MeSH primário: Processo Alveolar/anatomia & histologia
Processo Alveolar/diagnóstico por imagem
Tomografia Computadorizada de Feixe Cônico
Imagem Tridimensional
Incisivo
Maxila/anatomia & histologia
Maxila/diagnóstico por imagem
Raiz Dentária/anatomia & histologia
Raiz Dentária/diagnóstico por imagem
[Mh] Termos MeSH secundário: Adolescente
Adulto
Feminino
Seres Humanos
Masculino
Estudos Retrospectivos
Adulto Jovem
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171211
[Lr] Data última revisão:
171211
[Sb] Subgrupo de revista:D; IM
[Da] Data de entrada para processamento:171128
[St] Status:MEDLINE


  8 / 10981 MEDLINE  
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[PMID]:29019875
[Au] Autor:Hsu SY; Cheng HT; Manrique O; Hsu YC
[Ad] Endereço:Department of Plastic Surgery, China Medical University Hospital, Taichung, Taiwan.
[Ti] Título:Anterograde injection of low-dose urokinase salvages free anterolateral thigh flap: A case report of safe and effective treatment.
[So] Source:Medicine (Baltimore);96(41):e7932, 2017 Oct.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:RATIONALE: A 54-year-old Taiwanese male came to our hospital presented with right retromolar mucoepidermoid carcinoma. Composite resection and right modified radical neck dissection were performed. We then use free anteral lateral thigh flap to reconstruct the defect. However, venous congestion was found 32 h after the surgery. PATIENT CONCERNS: The main concerns of the patient is complete salvage of the free flap, and avoiding the secondary free flap harvesting and reconstruction surgeries. DIAGNOSES: Right retromolar mucoepidermoid carcinoma. INTERVENTIONS: We report the case of a patient with an anterolateral thigh flap with venous perianastomosis thrombosis and intraflap microvascular thrombosis successfully salvaged using anterograde intra-arterial injection of low-dose urokinase (60,000 U), without administering intravenous anticoagulation heparin during the postoperative period. OUTCOMES: The flap was completely salvaged 3 days after treatment. No other flap-associated or bleeding complications were noted. The intra-oral wounds around the flap completely healed without any post-ischemic complications. LESSONS SUBSECTIONS: Although the ideal urokinase doses and delivery procedures for free flap salvage have not been developed thus far, our method maximizes the urokinase gradient in the flap, minimizes the total dose required for flap salvage, and ensures no systemic spread. Thus, compared with other thrombolytic agents, urokinase may be more effective and safe for free flap salvage. With more experience, a standardized dosage and procedure can be developed.
[Mh] Termos MeSH primário: Carcinoma Mucoepidermoide
Neoplasias Maxilomandibulares
Complicações Pós-Operatórias
Retalhos Cirúrgicos/irrigação sanguínea
Trombectomia/métodos
Trombose
Ativador de Plasminogênio Tipo Uroquinase/administração & dosagem
Procedimentos Cirúrgicos Vasculares/efeitos adversos
[Mh] Termos MeSH secundário: Processo Alveolar/cirurgia
Carcinoma Mucoepidermoide/patologia
Carcinoma Mucoepidermoide/cirurgia
Fibrinolíticos/administração & dosagem
Neoplasias de Cabeça e Pescoço/patologia
Neoplasias de Cabeça e Pescoço/cirurgia
Seres Humanos
Neoplasias Maxilomandibulares/patologia
Neoplasias Maxilomandibulares/cirurgia
Masculino
Meia-Idade
Esvaziamento Cervical/métodos
Complicações Pós-Operatórias/etiologia
Complicações Pós-Operatórias/terapia
Procedimentos Cirúrgicos Reconstrutivos/efeitos adversos
Procedimentos Cirúrgicos Reconstrutivos/métodos
Trombose/etiologia
Trombose/terapia
Resultado do Tratamento
Procedimentos Cirúrgicos Vasculares/métodos
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Fibrinolytic Agents); EC 3.4.21.73 (Urokinase-Type Plasminogen Activator)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171122
[Lr] Data última revisão:
171122
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:171012
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000007932


  9 / 10981 MEDLINE  
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[PMID]:28962735
[Au] Autor:Yatabe M; Natsumeda GM; Miranda F; Janson G; Garib D
[Ad] Endereço:Department of Orthodontics, Bauru Dental School, University of São Paulo, Bauru, São Paulo, Brazil. Electronic address: msyatabe@yahoo.com.br.
[Ti] Título:Alveolar bone morphology of maxillary central incisors near grafted alveolar clefts after orthodontic treatment.
[So] Source:Am J Orthod Dentofacial Orthop;152(4):501-508.e1, 2017 Oct.
[Is] ISSN:1097-6752
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:INTRODUCTION: The aim of this study was to evaluate the thickness and the height of the maxillary central incisors' alveolar bone near the grafted alveolar cleft area, after comprehensive orthodontic treatment. METHODS: The sample comprised 30 patients with unilateral alveolar cleft with a mean age of 20.5 years (range, 17-25.8 years). High-resolution cone-beam computed tomography images of the maxilla were obtained 6 to 24 months after the comprehensive orthodontic treatment. The contralateral maxillary central incisor was used as a comparison group. Axial sections at the level of the central incisor root were used to measure the labial and lingual alveolar bone thicknesses. Cross sections were used to measure the bone crest heights using the cementoenamel junction as the reference. Paired t and Wilcoxon tests were used to compare the cleft and noncleft sides. RESULTS: The labial and lingual bone thicknesses of the maxillary central incisors' alveolar bone were significantly thinner (0.16 and 0.39 mm, respectively), and the labial alveolar crest height distance was significantly greater on the cleft side compared with the noncleft side (-1.2 mm). CONCLUSIONS: In patients with unilateral cleft lip and palate, the maxillary central incisors adjacent to the grafted alveolar cleft had thinner labial and lingual alveolar bones and an apically displaced labial alveolar crest level than the controls.
[Mh] Termos MeSH primário: Enxerto de Osso Alveolar
Processo Alveolar/anatomia & histologia
Processo Alveolar/diagnóstico por imagem
Fenda Labial/cirurgia
Fissura Palatina/cirurgia
Tomografia Computadorizada de Feixe Cônico
Incisivo
Ortodontia Corretiva
[Mh] Termos MeSH secundário: Adolescente
Adulto
Seres Humanos
Maxila
Estudos Retrospectivos
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171019
[Lr] Data última revisão:
171019
[Sb] Subgrupo de revista:D; IM
[Da] Data de entrada para processamento:171001
[St] Status:MEDLINE


  10 / 10981 MEDLINE  
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[PMID]:28910382
[Au] Autor:Corte GM; Plendl J; Hünigen H; Richardson KC; Gemeinhardt O; Niehues SM
[Ad] Endereço:Institute of Veterinary Anatomy, Department of Veterinary Medicine, Freie Universität Berlin, Berlin, Germany.
[Ti] Título:Refining experimental dental implant testing in the Göttingen Minipig using 3D computed tomography-A morphometric study of the mandibular canal.
[So] Source:PLoS One;12(9):e0184889, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:This study reports morphometric and age-related data of the mandibular canal and the alveolar ridge of the Göttingen Minipig to avoid complications during in vivo testing of endosseus dental implants and to compare these data with the human anatomy. Using 3D computed tomography, six parameters of the mandibular canal as well as the alveolar bone height and the alveolar ridge width were measured in Göttingen Minipigs aged 12, 17 and 21 months. Our null hypothesis assumes that the age and the body mass have an influence on the parameters measured. The study found that the volume, length and depth of the mandibular canal all increase with age. The width of the canal does not change significantly with age. The body mass does not have an influence on any of the measured parameters. The increase in canal volume appears to be due to loss of deep spongy bone in the posterior premolar and molar regions. This reduces the available space for dental implantations, negatively affecting implant stability and potentially the integrity of the inferior alveolar neurovascular bundle. Dynamic anatomical changes occur until 21 months. On ethical grounds, using minipigs younger than 21 months in experimental implant dentistry is inadvisable. Paradoxically the measurements of the 12 months old pigs indicate a closer alignment of their mandibular anatomy to that of humans suggesting that they may be better models for implant studies. Given the variability in mandibular canal dimensions in similar age cohorts, the use of imaging techniques is essential for the selection of individual minipigs for dental prosthetic interventions and thus higher success rates.
[Mh] Termos MeSH primário: Processo Alveolar/diagnóstico por imagem
Implantação Dentária Endo-Óssea/métodos
Mandíbula/diagnóstico por imagem
Tomografia Computadorizada por Raios X/métodos
[Mh] Termos MeSH secundário: Fatores Etários
Processo Alveolar/anatomia & histologia
Animais
Índice de Massa Corporal
Implantes Dentários
Modelos Animais de Doenças
Feminino
Seres Humanos
Masculino
Mandíbula/anatomia & histologia
Suínos
Porco Miniatura
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Dental Implants)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171012
[Lr] Data última revisão:
171012
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170915
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0184889



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