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[PMID]:28470359
[Au] Autor:Topuz MF; Sari M; Binnetoglu A; Dogrul R; Bugdayci O; Seker A
[Ad] Endereço:Department of Otorhinolaryngology, Dumlupinar University School of Medicine, Istiklal Parish Okmeydani st. No: 10 Merkez, Kütahya, Turkey. drfatihtopuz@yahoo.com.
[Ti] Título:Is endoscopic endonasal transsphenoidal surgery increases the susceptibility to rhinosinusitis.
[So] Source:Eur Arch Otorhinolaryngol;274(8):3065-3069, 2017 Aug.
[Is] ISSN:1434-4726
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:The aim of the study was to analyze whether the measurement of changes in the anatomical position and volume of middle concha, the volume changes in the area between the middle concha and lamina papyracea, the evaluation of opacification in major paranasal sinuses, and osteomeatal complex occlusion in cases with middle concha by out-fracture technique during endoscopic endonasal transsphenoidal approach is a minimally invasive surgery, and also to find out whether these changes lead to the development of tendency to rhinosinusitis. It was a retrospective clinical study. Forty-five cases, between 2013 and 2015, planned for endoscopic endonasal transsphenoidal surgery due to hypophyseal pathology at the Neurosurgery Departments of Marmara University Hospital were evaluated retrospectively. The patients were evaluated for the changes in the anatomy of the middle concha and the effects of these changes to paranasal sinuses by paranasal computed tomographies were studied at the preoperative second week and postoperative 12 month. The Lund-Mackay scoring system was used for the evaluation of opacification in the five major paranasal sinuses and occlusion of the osteomeatal complex in the pre- and postoperative period. The Lund-Mackay scoring system was used to analyze the paranasal computed tomography of the patients at the preoperative 2 weeks and postoperative first year. According to the Lund-Mackay scoring system, no significant difference was detected between the preoperative and postoperative opacification of paranasal sinuses (p > 0.05). Besides, there was also no significant difference between the preoperative and postoperative osteomeatal complex occlusion (p > 0.05). Considering the distance between middle concha and lamina papyracea following the out-fracture of the middle concha, a significant lateralization of 0.5 mm between the preoperative and postoperative period was observed (p < 0.05). In addition, a significant change was also detected in the volume of middle concha (p < 0.05). The volume of the area between the middle concha and lamina papyracea was decreased with a statistical significance (p < 0.05). The endoscopic endonasal transsphenoidal surgery causes some variations in the structures of the middle concha, paranasal sinuses, and OMC, but these changes do not lead to significant rhinologic pathologies.
[Mh] Termos MeSH primário: Cirurgia Endoscópica por Orifício Natural
Rinite/etiologia
Sinusite/etiologia
[Mh] Termos MeSH secundário: Adulto
Idoso
Suscetibilidade a Doenças
Feminino
Seres Humanos
Masculino
Meia-Idade
Cirurgia Endoscópica por Orifício Natural/efeitos adversos
Nariz
Seios Paranasais/diagnóstico por imagem
Doenças da Hipófise/cirurgia
Estudos Retrospectivos
Osso Esfenoide
Conchas Nasais/diagnóstico por imagem
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180306
[Lr] Data última revisão:
180306
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170505
[St] Status:MEDLINE
[do] DOI:10.1007/s00405-017-4598-4


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[PMID]:28468205
[Au] Autor:Yucel S; Gunbey HP; Gunbey E; Sayit AT; Aslan K
[Ad] Endereço:*Department of Radiology †Department of Otorhinolaryngology Head and Neck Surgery, Faculty of Medicine, Ondokuz Mayis University, Samsun, Turkey.
[Ti] Título:A Rare Concha Variation: Coronal Cleft.
[So] Source:J Craniofac Surg;28(3):e242-e244, 2017 May.
[Is] ISSN:1536-3732
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Nasal turbinates are embryologically derived from a series of outgrowths from the foetal lateral nasal wall. These outgrowths form a series of ridges, referred to as "ethmoturbinals" and have several vital functions. Several different turbinate variations have been reported so far. The authors presented 3 patients of coronal clefted concha who were diagnosed with magnetic resonance imaging. Computed tomography scans and nasal endoscopic examinations are also performed subsequently. These patients are the first coronal clefted concha cases in the literature and also the first radiological study defining concha cleft. This shows paucity of data documenting variations in the lateral nasal wall. Understanding the anatomy and the anatomic variations of the nasal cavity and nasal turbinates is critical to guide the procedure due to its close proximity to vital structures such as orbita and skull base, especially for functional endoscopic sinus surgery that is a widely used technique nowadays.
[Mh] Termos MeSH primário: Pavilhão Auricular/anormalidades
Pavilhão Auricular/diagnóstico por imagem
Conchas Nasais/embriologia
[Mh] Termos MeSH secundário: Idoso
Endoscopia
Feminino
Seres Humanos
Imagem por Ressonância Magnética
Masculino
Meia-Idade
Tomografia Computadorizada por Raios X
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180205
[Lr] Data última revisão:
180205
[Sb] Subgrupo de revista:D
[Da] Data de entrada para processamento:170505
[St] Status:MEDLINE
[do] DOI:10.1097/SCS.0000000000003451


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[PMID]:28468215
[Au] Autor:Erdur O; Ozturk K; Aksoy C
[Ad] Endereço:Department of Otolaryngology, Selcuk University, Konya, Turkey.
[Ti] Título:Conchae Bullosis in a Pediatric Patient.
[So] Source:J Craniofac Surg;28(3):e266-e267, 2017 May.
[Is] ISSN:1536-3732
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Pneumatization of the turbinates called concha bullosa is one of the most frequent anatomic variations of the nasal cavity. We report the first case of computed tomography findings of bilateral middle and inferior concha bullosa in a 13-year-old child with nasal obstruction. Here we describe a patient with extreme bilateral bullosa of inferior and middle conchas, as well as crista galli. The patient was treated successfully with endoscopic surgery of conchas. Nasal obstruction secondary to a bilateral turbinate bullosis in a child has not been described before. The clinicians should take this entity into consideration when evaluating the pediatric patients with nasal obstruction.
[Mh] Termos MeSH primário: Anormalidades Craniofaciais/diagnóstico por imagem
Obstrução Nasal/etiologia
Tomografia Computadorizada por Raios X
Conchas Nasais/anormalidades
[Mh] Termos MeSH secundário: Adolescente
Anormalidades Craniofaciais/complicações
Anormalidades Craniofaciais/cirurgia
Endoscopia
Seres Humanos
Masculino
Conchas Nasais/diagnóstico por imagem
Conchas Nasais/cirurgia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180202
[Lr] Data última revisão:
180202
[Sb] Subgrupo de revista:D
[Da] Data de entrada para processamento:170505
[St] Status:MEDLINE
[do] DOI:10.1097/SCS.0000000000003543


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[PMID]:28975810
[Au] Autor:Harju T; Kivekäs I; Numminen J; Rautiainen M
[Ad] Endereço:1 Department of Otorhinolaryngology, Tampere University Hospital, Tampere, Finland.
[Ti] Título:Eustachian Tube Dysfunction-Related Symptoms in Chronic Nasal Obstruction Caused by Inferior Turbinate Enlargement.
[So] Source:Ann Otol Rhinol Laryngol;126(12):798-803, 2017 Dec.
[Is] ISSN:1943-572X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: The aim of this study was to evaluate the relationship between chronic nasal obstruction caused by inferior turbinate enlargement and Eustachian tube dysfunction-related symptoms using the Eustachian Tube Dysfunction Questionnaire (ETDQ-7) as an assessment method. METHODS: A total of 80 adults were enrolled. Group 1 comprised consecutive patients with enlarged inferior turbinates and group 2 comprised healthy controls. The ETDQ-7 scores and tympanometry results of both groups were analyzed and compared. RESULTS: The median total scores of the ETDQ-7 in groups 1 and 2 were 1.9 (interquartile range, 1.4-2.8) and 1.1 (interquartile range, 1.0-1.7), respectively ( P < .001). There was no significant difference in the abnormal tympanometry results between the groups. There was no significant difference in the ETDQ-7 total score between the patients with allergic sensitization and other patients in group 1. CONCLUSIONS: Patients with inferior turbinate enlargement have more symptoms related to Eustachian tube dysfunction than healthy controls. Most patients with Eustachian tube dysfunction had normal tympanometry and normal otoscopy, which indicates a baro-challenge-induced Eustachian tube dysfunction. Whether the patient has allergic sensitization or not does not seem to cause a difference in symptoms related to Eustachian tube dysfunction.
[Mh] Termos MeSH primário: Otopatias/etiologia
Tuba Auditiva
Obstrução Nasal/etiologia
Conchas Nasais/patologia
[Mh] Termos MeSH secundário: Testes de Impedância Acústica
Adulto
Estudos de Casos e Controles
Doença Crônica
Otopatias/patologia
Feminino
Seres Humanos
Hipertrofia
Masculino
Meia-Idade
Otoscopia
Inquéritos e Questionários
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171113
[Lr] Data última revisão:
171113
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:171005
[St] Status:MEDLINE
[do] DOI:10.1177/0003489417735538


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[PMID]:28608749
[Au] Autor:Brunner JP; Jawad BA; McCoul ED
[Ad] Endereço:1 Tulane University School of Medicine, Department of Otolaryngology-Head and Neck Surgery, New Orleans, Louisiana, USA.
[Ti] Título:Polypoid Change of the Middle Turbinate and Paranasal Sinus Polyposis Are Distinct Entities.
[So] Source:Otolaryngol Head Neck Surg;157(3):519-523, 2017 Sep.
[Is] ISSN:1097-6817
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Objectives Polypoid change of the middle turbinate (PCMT) is a finding on intranasal examination whose significance is not well understood. We present a comparison of the clinical characteristics of PCMT with paranasal sinus polyposis (PSP), a common condition with potentially similar appearance. Study Design Parallel case series. Setting Tertiary rhinology clinic. Subjects and Methods Data were prospectively compiled from consecutive patients during a 12-month period with either PSP arising from the middle meatus or PCMT limited to the middle turbinate as identified on nasal endoscopy. Recorded data included comorbidities, the 22-item Sinonasal Outcome Test (SNOT-22), Nasal Obstruction Symptom Evaluation (NOSE), Lund-Mackay score from computed tomography (CT) imaging, and total eosinophil levels. Results Of 593 patients, 23 (3.9%) had PCMT and 44 (7.4%) had PSP. The PSP group was predominantly male (75% vs 52%, P < .001) with an older mean age (53.4 vs 35.4 years, P < .0001). PCMT was more often associated with allergic rhinitis (83% vs 34%, P < .001), whereas PCMT was rarely associated with chronic rhinosinusitis (10% vs 100%, P < .0001). Mean eosinophil count (7.1 vs 3.1, P = .096) was not significantly different between groups, whereas mean Lund-Mackay score was higher in PSP (14.9 vs 2.8, P < .0008). Mean NOSE score was greater in PSP (65.3 vs 46.8, P = .025), whereas SNOT-22 score was comparable between groups (40.6 vs 34.6, P = .29). Conclusion PCMT is a unique physical finding with clinical associations that distinguish it from PSP. PCMT has greater association with allergic rhinitis than chronic rhinosinusitis, and both PCMT and PSP are associated with impaired quality of life.
[Mh] Termos MeSH primário: Pólipos Nasais/patologia
Seios Paranasais/patologia
Conchas Nasais/patologia
[Mh] Termos MeSH secundário: Adulto
Diagnóstico Diferencial
Feminino
Seres Humanos
Masculino
Meia-Idade
Estudos Prospectivos
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170929
[Lr] Data última revisão:
170929
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170614
[St] Status:MEDLINE
[do] DOI:10.1177/0194599817711887


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[PMID]:28590975
[Au] Autor:Zaimi I; Di Fulvio F; Borgognone A; Gherardini G
[Ad] Endereço:Department of Surgery, Erasmus University Medical Center, Rotterdam, The Netherlands Ear Nose and Throat, Rome, Italy Division of Burns and Plastic-Reconstructive Surgery, Roma C Local Healthcare, Rome, Italy Plastic Surgery, Rome, Italy.
[Ti] Título:A Safe and Inexpensive Technique for Turbinate Cauterization Surgery.
[So] Source:Plast Reconstr Surg;140(3):520e-522e, 2017 09.
[Is] ISSN:1529-4242
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Eletrocoagulação/métodos
Rinoplastia/métodos
Conchas Nasais/cirurgia
[Mh] Termos MeSH secundário: Eletrocoagulação/economia
Eletrocoagulação/instrumentação
Seres Humanos
Agulhas
Países Baixos
Segurança do Paciente
Rinoplastia/economia
Rinoplastia/instrumentação
[Pt] Tipo de publicação:LETTER
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171109
[Lr] Data última revisão:
171109
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170608
[St] Status:MEDLINE
[do] DOI:10.1097/PRS.0000000000003640


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[PMID]:28546154
[Au] Autor:Kang JW; Lee YH; Kang MJ; Lee HJ; Oh R; Min HJ; Namkung W; Choi JY; Lee SN; Kim CH; Yoon JH; Cho HJ
[Ad] Endereço:Department of Otorhinolaryngology, Jeju National University College of Medicine, Jeju, Korea; and.
[Ti] Título:Synergistic mucus secretion by histamine and IL-4 through TMEM16A in airway epithelium.
[So] Source:Am J Physiol Lung Cell Mol Physiol;313(3):L466-L476, 2017 Sep 01.
[Is] ISSN:1522-1504
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Histamine is an important mediator of allergic reactions, and mucus hypersecretion is a major allergic symptom. However, the direct effect of histamine on mucus secretion from airway mucosal epithelia has not been clearly demonstrated. TMEM16A is a Ca -activated chloride channel, and it is closely related to fluid secretion in airway mucosal epithelia. We investigated whether histamine directly induces fluid secretion from epithelial cells or submucosal glands (SMG) and mechanisms related, therewith, in allergic airway diseases. In pig airway tissues from the nose or trachea, histamine was a potent secretagogue that directly induced strong responses. However, gland secretion from human nasal tissue was not induced by histamine, even in allergic rhinitis patients. Histamine type 1 receptor (H1R) and histamine type 2 receptor (H2R) were not noted in SMG by in situ hybridization. Cultured primary human nasal epithelial (NHE) cells were used for the measurement of short-circuit current changes with the Ussing chamber. Histamine-induced slight responses of anion secretions under normal conditions. The response was enhanced by IL-4 stimulation through TMEM16A, which might be related to fluid hypersecretion in allergic rhinitis. Pretreatment with IL-4 augmented the histamine response that was suppressed by a TMEM16A inhibitor. TMEM16A expression was enhanced by 24-h treatment of IL-4 in human nasal epithelial cells. The expression of TMEM16A was significantly elevated in an allergic rhinitis group, compared with a control group. We elucidated histamine-induced fluid secretions in synergy with IL-4 through TMEM16A in the human airway epithelium. In addition, we observed species differences between pigs and humans in terms of gland secretion of histamine.
[Mh] Termos MeSH primário: Canais de Cloreto/metabolismo
Histamina/farmacologia
Interleucina-4/farmacologia
Muco/secreção
Proteínas de Neoplasias/metabolismo
Mucosa Respiratória/secreção
[Mh] Termos MeSH secundário: Adulto
Animais
Anoctamina-1
Células Cultivadas
Células Epiteliais/efeitos dos fármacos
Células Epiteliais/metabolismo
Regulação da Expressão Gênica/efeitos dos fármacos
Seres Humanos
Ativação do Canal Iônico/efeitos dos fármacos
Modelos Biológicos
Nariz/metabolismo
RNA Mensageiro/genética
RNA Mensageiro/metabolismo
Receptores Histamínicos/genética
Receptores Histamínicos/metabolismo
Mucosa Respiratória/efeitos dos fármacos
Rinite Alérgica/metabolismo
Rinite Alérgica/patologia
Sus scrofa
Traqueia/patologia
Conchas Nasais/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (ANO1 protein, human); 0 (Anoctamin-1); 0 (Chloride Channels); 0 (Neoplasm Proteins); 0 (RNA, Messenger); 0 (Receptors, Histamine); 207137-56-2 (Interleukin-4); 820484N8I3 (Histamine)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170527
[St] Status:MEDLINE
[do] DOI:10.1152/ajplung.00103.2017


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[PMID]:28508726
[Au] Autor:Scangas GA; Remenschneider AK; Bleier BS; Holbrook EH; Gray ST; Metson RB
[Ad] Endereço:1 Department of Otolaryngology, Harvard Medical School, Boston, Massachusetts, USA.
[Ti] Título:Does the Timing of Middle Turbinate Resection Influence Quality-of-Life Outcomes for Patients with Chronic Rhinosinusitis?
[So] Source:Otolaryngol Head Neck Surg;157(5):874-879, 2017 Nov.
[Is] ISSN:1097-6817
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Objective To evaluate the impact of bilateral middle turbinate resection (BMTR) on patient-reported quality of life following primary and revision endoscopic sinus surgery (ESS) for chronic rhinosinusitis (CRS). Study Design Prospective cohort study. Setting Tertiary care center. Subjects and Methods Patients with CRS who were recruited from 11 otolaryngologic practices completed the Sino-Nasal Outcome Test-22, Chronic Sinusitis Survey, and EuroQol 5-Dimension questionnaires at baseline, as well as 3 and 12 months after ESS. In the primary ESS cohort (n = 406), patients who underwent BMTR (n = 78) at the time of surgery were compared with patients (n = 328) whose middle turbinates were preserved. In the revision ESS cohort (n = 363), a similar comparison was made between patients who did (n = 64) and did not (n = 299) undergo BMTR. Results Sino-Nasal Outcome Test-22, Chronic Sinusitis Survey, and EuroQol 5-Dimension scores showed similar improvements for both the turbinate resection and preservation cohorts at 3 months ( P < .001) and 12 months ( P < .001) after surgery. For patients who underwent revision surgery, the performance of BMTR resulted in greater improvement in Chronic Sinusitis Survey scores at 1 year as compared with the turbinate preservation group (change from baseline: 28.1 vs 20.7, respectively; P = .026). History of tobacco use and the presence of nasal polyps did not affect clinical outcomes at any time point. Conclusion Patients who underwent BMTR during primary and revision sinus surgery reported similar benefits in quality-of-life outcomes 1 year after surgery. In select patients undergoing revision sinus surgery, the performance of BMTR results in improved disease-specific quality of life.
[Mh] Termos MeSH primário: Endoscopia/métodos
Qualidade de Vida
Rinite/cirurgia
Sinusite/cirurgia
Conchas Nasais/cirurgia
[Mh] Termos MeSH secundário: Doença Crônica
Feminino
Seres Humanos
Masculino
Meia-Idade
Estudos Prospectivos
Inquéritos e Questionários
Resultado do Tratamento
[Pt] Tipo de publicação:JOURNAL ARTICLE; MULTICENTER STUDY
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171106
[Lr] Data última revisão:
171106
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170517
[St] Status:MEDLINE
[do] DOI:10.1177/0194599817706929


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[PMID]:28417704
[Au] Autor:Uluyol S
[Ad] Endereço:1 Department of Otorhinolaryngology, Van Training and Research Hospital, Van, Turkey.
[Ti] Título:Effects of Silver Nitrate Cauterization on Middle Turbinate Synechia after Endoscopic Sinus Surgery.
[So] Source:Otolaryngol Head Neck Surg;157(3):515-518, 2017 Sep.
[Is] ISSN:1097-6817
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Objective This study aimed to examine the efficacy of silver nitrate cauterization of the middle turbinate (MT) for hindering postoperative middle meatal synechia formation after endoscopic sinus surgery (ESS). Study Design Prospective, controlled, and single-blinded. Settings Tertiary referral center. Subjects and Methods For this study, 38 patients undergoing bilateral ESS due to nasal polyposis were recruited. Following ESS, silver nitrate cauterization of the lateral side of the left MT was performed in all cases. The noncauterized opposite right sides served as controls. All patients received the standard ESS protocol, intraoperative middle meatal packing, and postoperative management. The main outcome measured was the formation of partial or complete MT synechia at the end of 6-month assessment, performed by a blinded observer. Results At the end of the 6-month follow-up period, MT synechia formation was observed in 7 of the right sides (7 of 38, 18.4%) and none in any left sides. The rate of synechia formation was significantly higher in the controls when compared with the silver nitrate-cauterized sides ( P < .001). Conclusion The results of this study suggest that silver nitrate cauterization of the MT is a practical and efficient method to eliminate middle meatal synechia after ESS.
[Mh] Termos MeSH primário: Cauterização/métodos
Endoscopia
Pólipos Nasais/cirurgia
Doenças Nasais/cirurgia
Seios Paranasais/cirurgia
Complicações Pós-Operatórias/cirurgia
Nitrato de Prata
Aderências Teciduais/cirurgia
Conchas Nasais/cirurgia
[Mh] Termos MeSH secundário: Adulto
Feminino
Seres Humanos
Masculino
Meia-Idade
Estudos Prospectivos
Método Simples-Cego
Resultado do Tratamento
Adulto Jovem
[Pt] Tipo de publicação:CONTROLLED CLINICAL TRIAL; JOURNAL ARTICLE
[Nm] Nome de substância:
95IT3W8JZE (Silver Nitrate)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170929
[Lr] Data última revisão:
170929
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170419
[St] Status:MEDLINE
[do] DOI:10.1177/0194599817702875


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[PMID]:28407251
[Au] Autor:Mangin D; Bequignon E; Zerah-Lancner F; Isabey D; Louis B; Adnot S; Papon JF; Coste A; Boyer L; Devars du Mayne M
[Ad] Endereço:Department of Otorhinolaryngology and Facial Cervical Surgery, Intercommunal Hospital Center of Créteil, Créteil, France.
[Ti] Título:Investigating hyperventilation syndrome in patients suffering from empty nose syndrome.
[So] Source:Laryngoscope;127(9):1983-1988, 2017 Sep.
[Is] ISSN:1531-4995
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVES/HYPOTHESIS: Patients with empty nose syndrome (ENS) following turbinate surgery often complain about breathing difficulties. We set out to determine if dyspnea in patients with ENS was associated with hyperventilation syndrome (HVS). We hypothesized that lower airway symptoms in ENS could be explained by HVS. STUDY DESIGN: Observational prospective study. METHODS: All consecutive patients referred to our center for ENS over 1 year were invited to participate. Patients completed the Nijmegen score and underwent a hyperventilation provocation test (HVPT) and arterial blood gas and cardiopulmonary tests. HVS was defined by a delayed return of the end-tidal partial pressure of carbon dioxide in the expired gas to baseline during HVPT. Patients with HVS were asked to complete the Sinonasal Outcome Test (SNOT)-16 questionnaire before and after a specific eight-session respiratory rehabilitation program. RESULTS: Twenty-two of the 29 patients referred for ENS during the study period were eligible for inclusion and underwent a complete workup. HVS was diagnosed in 17 of these patients (77.3%). In the five patients who completed the SNOT-16, the score was significantly lower after rehabilitation. CONCLUSIONS: This study suggests that HVS is frequent in patients with ENS, and that symptoms can be improved by respiratory rehabilitation. Pathophysiological links between ENS and HVS deserve to be further explored. LEVEL OF EVIDENCE: 2b Laryngoscope, 127:1983-1988, 2017.
[Mh] Termos MeSH primário: Hiperventilação/fisiopatologia
Obstrução Nasal/fisiopatologia
Procedimentos Cirúrgicos Nasais/efeitos adversos
Complicações Pós-Operatórias/fisiopatologia
[Mh] Termos MeSH secundário: Adulto
Monitorização Transcutânea dos Gases Sanguíneos
Testes de Provocação Brônquica
Dispneia/etiologia
Dispneia/fisiopatologia
Dispneia/reabilitação
Feminino
Seres Humanos
Hiperventilação/etiologia
Masculino
Meia-Idade
Obstrução Nasal/etiologia
Obstrução Nasal/reabilitação
Procedimentos Cirúrgicos Nasais/reabilitação
Complicações Pós-Operatórias/etiologia
Complicações Pós-Operatórias/reabilitação
Estudos Prospectivos
Inquéritos e Questionários
Síndrome
Volume de Ventilação Pulmonar
Resultado do Tratamento
Conchas Nasais/cirurgia
[Pt] Tipo de publicação:JOURNAL ARTICLE; OBSERVATIONAL STUDY
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170915
[Lr] Data última revisão:
170915
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170414
[St] Status:MEDLINE
[do] DOI:10.1002/lary.26599



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