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  1 / 21203 MEDLINE  
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[PMID]:29364924
[Au] Autor:Chan GC; Divers J; Russell GB; Langefeld CD; Wagenknecht LE; Xu J; Smith SC; Bowden DW; Register TC; Carr JJ; Lenchik L; Freedman BI
[Ad] Endereço:Department of Internal Medicine, Section on Nephrology, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America.
[Ti] Título:Adipose tissue depot volume relationships with spinal trabecular bone mineral density in African Americans with diabetes.
[So] Source:PLoS One;13(1):e0191674, 2018.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Changes in select adipose tissue volumes may differentially impact bone mineral density. This study was performed to assess cross-sectional and longitudinal relationships between computed tomography-determined visceral (VAT), subcutaneous (SAT), inter-muscular (IMAT), and pericardial adipose tissue (PAT) volumes with respective changes in thoracic vertebral and lumbar vertebral volumetric trabecular bone mineral density (vBMD) in African Americans with type 2 diabetes. Generalized linear models were fitted to test relationships between baseline and change in adipose volumes with change in vBMD in 300 African American-Diabetes Heart Study participants; adjustment was performed for age, sex, diabetes duration, study interval, smoking, hypertension, BMI, kidney function, and medications. Participants were 50% female with mean ± SD age 55.1±9.0 years, diabetes duration 10.2±7.2 years, and BMI 34.7±7.7 kg/m2. Over 5.3 ± 1.4 years, mean vBMD decreased in thoracic/lumbar spine, while mean adipose tissue volumes increased in SAT, IMAT, and PAT, but not VAT depots. In fully-adjusted models, changes in lumbar and thoracic vBMD were positively associated with change in SAT (ß[SE] 0.045[0.011], p<0.0001; 0.40[0.013], p = 0.002, respectively). Change in thoracic vBMD was positively associated with change in IMAT (p = 0.029) and VAT (p = 0.016); and change in lumbar vBMD positively associated with baseline IMAT (p<0.0001). In contrast, vBMD was not associated with change in PAT. After adjusting for BMI, baseline and change in volumes of select adipose depots were associated with increases in thoracic and lumbar trabecular vBMD in African Americans. Effects of adiposity on trabecular bone appear to be site-specific and related to factors beyond mechanical load.
[Mh] Termos MeSH primário: Tecido Adiposo/patologia
Afroamericanos
Densidade Óssea
Diabetes Mellitus Tipo 2/fisiopatologia
Coluna Vertebral/patologia
[Mh] Termos MeSH secundário: Adulto
Feminino
Seres Humanos
Estudos Longitudinais
Masculino
Meia-Idade
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180309
[Lr] Data última revisão:
180309
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180125
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0191674


  2 / 21203 MEDLINE  
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[PMID]:29480856
[Au] Autor:Yuan B; Ji W; Fan B; Zhang B; Zhao Y; Li J
[Ad] Endereço:Department of Orthopaedics.
[Ti] Título:Association analysis between thrombospondin-2 gene polymorphisms and intervertebral disc degeneration in a Chinese Han population.
[So] Source:Medicine (Baltimore);97(2):e9586, 2018 Jan.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The aim of this study is to determine the contribution of 2 single nucleotide polymorphisms (SNPs) in thrombospondin 2 (THBS2) gene to the development of intervertebral disc degeneration (IDD) in a Chinese Han population.We studied 138 patients with radiographically proven IDD and 136 healthy volunteers with no history of back problems. Magnetic resonance images (MRIs) were obtained for all the patients and controls. Image evaluation for IDD was performed to evaluate the severity of IDD. All patients and controls were genotyped for rs6422747 and rs6422748. Associations between genotypes and development of IDD were analyzed.We found that 2 SNPs in the intron region of THBS2 gene (rs6422747 and rs6422748) were associated with susceptibility of IDD. However, they were not related with severity of IDD, including the total number of degenerative disc and level of IDD. G allele in both SNPs was associated with a higher risk of IDD.The 2 SNPs (rs6422747 and rs6422748) in the THBS2 gene were associated with susceptibility of IDD but not severity of IDD in a Chinese Han population. Our results indicated that THBS2 gene polymorphisms might be the risk factors for IDD. More studies with larger sample size need to be perfected to make sure the functions of THBS2 gene polymorphisms in IDD development.
[Mh] Termos MeSH primário: Predisposição Genética para Doença
Degeneração do Disco Intervertebral/genética
Polimorfismo de Nucleotídeo Único
Trombospondinas/genética
[Mh] Termos MeSH secundário: Grupo com Ancestrais do Continente Asiático/genética
China
Feminino
Técnicas de Genotipagem
Seres Humanos
Degeneração do Disco Intervertebral/diagnóstico por imagem
Íntrons
Imagem por Ressonância Magnética
Masculino
Meia-Idade
Índice de Gravidade de Doença
Coluna Vertebral/diagnóstico por imagem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Thrombospondins); 0 (thrombospondin 2)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180305
[Lr] Data última revisão:
180305
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180227
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000009586


  3 / 21203 MEDLINE  
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[PMID]:29251851
[Au] Autor:Kumbar SM; Lad SB
[Ti] Título:Estimation of age and longevity of freshwater fish Salmophasia balookee from otoliths, scales and vertebrae.
[So] Source:J Environ Biol;37(5):943-7, 2016 09.
[Is] ISSN:0254-8704
[Cp] País de publicação:India
[La] Idioma:eng
[Mh] Termos MeSH primário: Envelhecimento/fisiologia
Escamas de Animais/crescimento & desenvolvimento
Cyprinidae/fisiologia
Longevidade/fisiologia
Membrana dos Otólitos/crescimento & desenvolvimento
Coluna Vertebral/anatomia & histologia
[Mh] Termos MeSH secundário: Animais
Coluna Vertebral/crescimento & desenvolvimento
[Pt] Tipo de publicação:RESEARCH SUPPORT, NON-U.S. GOV'T; JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180222
[Lr] Data última revisão:
180222
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171219
[St] Status:MEDLINE


  4 / 21203 MEDLINE  
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[PMID]:29324892
[Au] Autor:Berg F; Almeland OW; Skadal J; Slotte A; Andersson L; Folkvord A
[Ad] Endereço:University of Bergen, Department of Biology, Bergen, Norway.
[Ti] Título:Genetic factors have a major effect on growth, number of vertebrae and otolith shape in Atlantic herring (Clupea harengus).
[So] Source:PLoS One;13(1):e0190995, 2018.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Atlantic herring, Clupea harengus, have complex population structures. Mixing of populations is known, but the extent of connectivity is still unclear. Phenotypic plasticity results in divergent phenotypes in response to environmental factors. A marked salinity gradient occurs from Atlantic Ocean (salinity 35) into the Baltic Sea (salinity range 2-12). Herring from both habitats display phenotypic and genetic variability. To explore how genetic factors and salinity influence phenotypic traits like growth, number of vertebrae and otolith shape an experimental population consisting of Atlantic purebreds and Atlantic/Baltic F1 hybrids were incubated and co-reared at two different salinities, 16 and 35, for three years. The F1-generation was repeatedly sampled to evaluate temporal variation. A von Bertalanffy growth model indicated that reared Atlantic purebreds had a higher maximum length (26.2 cm) than Atlantic/Baltic hybrids (24.8 cm) at salinity 35, but not at salinity 16 (25.0 and 24.8 cm, respectively). In contrast, Atlantic/Baltic hybrids achieved larger size-at-age than the wild caught Baltic parental group. Mean vertebral counts and otolith aspect ratios were higher for reared Atlantic purebreds than Atlantic/Baltic hybrids, consistent with the differences between parental groups. There were no significant differences in vertebral counts and otolith aspect ratios between herring with the same genotype but raised in different salinities. A Canonical Analysis of Principal Coordinates was applied to analyze the variation in wavelet coefficients that described otolith shape. The first discriminating axis identified the differences between Atlantic purebreds and Atlantic/Baltic hybrids, while the second axis represented salinity differences. Assigning otoliths based on genetic groups (Atlantic purebreds vs. Atlantic/Baltic hybrids) yielded higher classification success (~90%) than based on salinities (16 vs. 35; ~60%). Our results demonstrate that otolith shape and vertebral counts have a significant genetic component and are therefore useful for studies on population dynamics and connectivity.
[Mh] Termos MeSH primário: Peixes/anatomia & histologia
Variação Genética
Crescimento
Membrana dos Otólitos/anatomia & histologia
Coluna Vertebral/anatomia & histologia
[Mh] Termos MeSH secundário: Animais
Feminino
Peixes/genética
Peixes/crescimento & desenvolvimento
Masculino
Dinâmica Populacional
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180215
[Lr] Data última revisão:
180215
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180112
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0190995


  5 / 21203 MEDLINE  
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[PMID]:29407505
[Au] Autor:Nardi C; De Falco L; Selvi V; Lorini C; Calistri L; Colagrande S
[Ad] Endereço:Department of Experimental and Clinical Biomedical Sciences, Radiodiagnostic Unit number 2, University of Florence, Azienda Ospedaliero, Universitaria Careggi, Florence, Italy. Electronic address: cosimo.nardi@unifi.it.
[Ti] Título:Role of cone-beam computed tomography with a large field of view in Goldenhar syndrome.
[So] Source:Am J Orthod Dentofacial Orthop;153(2):269-277, 2018 Feb.
[Is] ISSN:1097-6752
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:INTRODUCTION: Goldenhar syndrome is a rare disease with hemifacial microsomia and craniofacial disorders originating from the first and second branchial arches, such as ocular, auricular, and vertebral anomalies. The complexity and variety of the ways in which the disease presents itself usually need several examinations. In this study, we aimed to evaluate both craniofacial and vertebral skeletal anomalies and asymmetries between the nonaffected and affected sides in patients with Goldenhar syndrome by using cone-beam computed tomography. METHODS: Ten patients (7-14 years old; 6 boys, 4 girls) were evaluated via NewTom 5G cone-beam computed tomography (QR srl, Verona, Italy) with a large field of view (18 × 16 cm). Ten anatomic facial landmarks were identified to measure the following distances bilaterally: sella turcica (ST)-mandibular angle, ST-condyle, ST-mastoid, ST-mental foramen, ST-fronto zygomatic suture, ST-zygomatic temporal suture, ST-zygomatic facial foramen, ST-sphenopalatine fossa, mandibular angle-mandibular symphysis, and mandibular angle-condyle. The following 6 volumes were calculated bilaterally: orbit, maxillary sinus, condyle, external ear canal, middle ear, and internal auditory canal. These measurements were performed to assess skeletal asymmetries to compare the nonaffected side with the affected side by the Wilcoxon test. Cervical spine anomalies were classified into fusion anomalies and posterior arch deficiencies. RESULTS: All patients showed a deficit of skeletal development on the affected side. Statistically significant differences (0.001 ≤ P value ≤ 0.043) between the nonaffected and affected sides were recorded for all measurements, except for ST-frontozygomatic suture, mandibular angle-mandibular symphysis, and maxillary sinus volume. Vertebral fusion anomalies and posterior arch deficiencies were found in 7 and 4 patients, respectively. CONCLUSIONS: Cone-beam computed tomography with a large field of view was able to accurately identify craniofacial and vertebral skeletal anomalies, and to quantify asymmetries between the nonaffected and affected sides for an efficient maxillofacial treatment planning.
[Mh] Termos MeSH primário: Tomografia Computadorizada de Feixe Cônico
Síndrome de Goldenhar/diagnóstico por imagem
[Mh] Termos MeSH secundário: Adolescente
Criança
Tomografia Computadorizada de Feixe Cônico/métodos
Anormalidades Craniofaciais/diagnóstico por imagem
Feminino
Forame Magno/diagnóstico por imagem
Seres Humanos
Masculino
Mandíbula/diagnóstico por imagem
Côndilo Mandibular/diagnóstico por imagem
Processo Mastoide/diagnóstico por imagem
Sela Túrcica/diagnóstico por imagem
Coluna Vertebral/diagnóstico por imagem
Zigoma/diagnóstico por imagem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180213
[Lr] Data última revisão:
180213
[Sb] Subgrupo de revista:D; IM
[Da] Data de entrada para processamento:180207
[St] Status:MEDLINE


  6 / 21203 MEDLINE  
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[PMID]:29324879
[Au] Autor:Raoult V; Howell N; Zahra D; Peddemors VM; Howard DL; de Jonge MD; Buchan BL; Williamson JE
[Ad] Endereço:Department of Biological Sciences, Macquarie University, Sydney, NSW, Australia.
[Ti] Título:Localized zinc distribution in shark vertebrae suggests differential deposition during ontogeny and across vertebral structures.
[So] Source:PLoS One;13(1):e0190927, 2018.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The development of shark vertebrae and the possible drivers of inter- and intra-specific differences in vertebral structure are poorly understood. Shark vertebrae are used to examine life-history traits related to trophic ecology, movement patterns, and the management of fisheries; a better understanding of their development would be beneficial to many fields of research that rely on these calcified structures. This study used Scanning X-ray Fluorescence Microscopy to observe zinc distribution within vertebrae of ten shark species from five different orders. Zinc was mostly localised within the intermedialis and was generally detected at levels an order of magnitude lower in the corpus calcareum. In most species, zinc concentrations were higher pre-birth mark, indicating a high rate of pre-natal zinc deposition. These results suggest there are inter-specific differences in elemental deposition within vertebrae. Since the deposition of zinc is physiologically-driven, these differences suggest that the processes of growth and deposition are potentially different in the intermedialis and corpus calcareum, and that caution should be taken when extrapolating information such as annual growth bands from one structure to the other. Together these results suggest that the high inter-specific variation in vertebral zinc deposition and associated physiologies may explain the varying effectiveness of ageing methodologies applied to elasmobranch vertebrae.
[Mh] Termos MeSH primário: Envelhecimento/metabolismo
Tubarões/crescimento & desenvolvimento
Tubarões/metabolismo
Coluna Vertebral/crescimento & desenvolvimento
Coluna Vertebral/metabolismo
Zinco/metabolismo
[Mh] Termos MeSH secundário: Envelhecimento/patologia
Animais
Cálcio/metabolismo
Modelos Lineares
Microscopia de Fluorescência
Tubarões/anatomia & histologia
Especificidade da Espécie
Coluna Vertebral/diagnóstico por imagem
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
J41CSQ7QDS (Zinc); SY7Q814VUP (Calcium)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180206
[Lr] Data última revisão:
180206
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180112
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0190927


  7 / 21203 MEDLINE  
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[PMID]:29281728
[Au] Autor:Poorghasamians E; Aggabao PC; Wren TAL; Ponrartana S; Gilsanz V
[Ad] Endereço:Department of Radiology, Children's Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America.
[Ti] Título:Vertebral cross-sectional growth: A predictor of vertebral wedging in the immature skeleton.
[So] Source:PLoS One;12(12):e0190225, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The degree of vertebral wedging, a key structural characteristic of spinal curvatures, has recently been found to be negatively related to vertebral cross-sectional area (CSA). The purpose of this longitudinal study was to examine the relation between vertebral cross-sectional growth and vertebral wedging progression within the immature lumbar spine. Using magnetic resonance imaging (MRI), we analyzed the potential association between increases in lumbar vertebral CSA and changes in L5 vertebral wedging in 27 healthy adolescent girls (ages 9-13 years) twice within a two-year period. Vertebral CSA growth was negatively associated with changes in posteroanterior vertebral wedging (r = -0.61; p = 0.001). Multiple regression analysis showed that this relation was independent of gains in age, height, and weight. When compared to the 14 girls whose vertebral wedging progressed, the 13 subjects whose vertebral wedging decreased had significantly greater vertebral cross-sectional growth (0.39 ± 0.25 vs. 0.75 ± 0.23 cm2; p = 0.001); in contrast, there were no significant differences in increases in age, height, or weight between the two groups. Changes in posteroanterior vertebral wedging and the degree of lumbar lordosis (LL) positively correlated (r = 0.56, p = 0.002)-an association that persisted even after adjusting for gains in age, height, and weight. We concluded that in the immature skeleton, vertebral cross-sectional growth is an important determinant of the plasticity of the vertebral body; regression of L5 vertebral wedging is associated with greater lumbar vertebral cross-sectional growth, while progression is the consequence of lesser cross-sectional growth.
[Mh] Termos MeSH primário: Esqueleto
Coluna Vertebral/crescimento & desenvolvimento
[Mh] Termos MeSH secundário: Adolescente
Feminino
Seres Humanos
Imagem por Ressonância Magnética
Masculino
Coluna Vertebral/diagnóstico por imagem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180206
[Lr] Data última revisão:
180206
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171228
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0190225


  8 / 21203 MEDLINE  
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[PMID]:29281687
[Au] Autor:Jerve A; Qu Q; Sanchez S; Ahlberg PE; Haitina T
[Ad] Endereço:Biology Department, Imperial College London, Silwood Park Campus, Ascot, United Kingdom.
[Ti] Título:Vascularization and odontode structure of a dorsal ridge spine of Romundina stellina Ørvig 1975.
[So] Source:PLoS One;12(12):e0189833, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:There are two types of dermal skeletons in jawed vertebrates: placoderms and osteichthyans carry large bony plates (macromery), whereas chondrichthyans and acanthodians are covered by small scales (micromery). Fin spines are one of the last large dermal structures found on micromeric taxa and offer a potential source of histology and morphology that can be compared to those found on macromeric groups. Dermal fin spines offer a variety of morphology but aspects of their growth modes and homology are unclear. Here, we provide detailed descriptions of the microstructure and growth of a dorsal ridge spine from the acanthothoracid placoderm, Romundina stellina, using virtual three-dimensional paleohistological datasets. From these data we identify several layers of dentine ornamentation covering the lateral surfaces of the spine and reconstructed their growth pattern. We show that this spine likely grew posteriorly and proximally from a narrow portion of bone located along the leading edge of the spine. The spine is similarly constructed to the scales with a few exceptions, including the absence of polarized fibers distributed throughout the bone and the presence of a thin layer of perichondral bone. The composition of the spine (semidentine odontodes, dermal bone, perichondral bone) is identical to that of the Romundina dermal plates. These results illustrate the similarities and differences between the dermal tissues in Romundina and indicate that the spine grew differently from the dentinous fin spines from extant and fossil chondrichthyans. The morphology and histology of Romundina is most similar to the fin spine of the probable stem osteichthyan Lophosteus, with a well-developed inner cellular bony base and star-shaped odontodes on the surface. Results from these studies will undoubtedly have impact on our understanding of fossil fin spine histology and evolution, contributing to the on-going revision of early gnathostome phylogeny.
[Mh] Termos MeSH primário: Diatomáceas
Coluna Vertebral/anatomia & histologia
[Mh] Termos MeSH secundário: Animais
Fósseis
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180129
[Lr] Data última revisão:
180129
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171228
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0189833


  9 / 21203 MEDLINE  
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[PMID]:28460690
[Au] Autor:Ross GB; Sheahan PJ; Mahoney B; Gurd BJ; Hodges PW; Graham RB
[Ad] Endereço:School of Human Kinetics, Faculty of Health Sciences, University of Ottawa, Ottawa, Ontario, Canada; School of Kinesiology and Health Studies, Faculty of Arts & Science, Queen's University, Kingston, Ontario, Canada.
[Ti] Título:Pain catastrophizing moderates changes in spinal control in response to noxiously induced low back pain.
[So] Source:J Biomech;58:64-70, 2017 06 14.
[Is] ISSN:1873-2380
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:It is generally accepted that spine control and stability are relevant for the prevention and rehabilitation of low back pain (LBP). However, there are conflicting results in the literature in regards to how these variables are modified in the presence of LBP. The aims of the present work were twofold: (1) to use noxious stimulation to induce LBP in healthy individuals to assess the direct effects of pain on control (quantified by the time-dependent behavior of kinematic variance), and (2) to assess whether the relationship between pain and control is moderated by psychological features (i.e. pain catastrophizing (PC) and kinesiophobia). Participants completed three conditions (baseline, pain, recovery) during a task involving completion of 35 cycles of a repetitive unloaded spine flexion/extension movement. The neuromuscular control of spine movements was assessed during each condition using maximum finite-time Lyapunov exponents (λ ). Nociceptive stimulus involved injection of hypertonic saline into the interspinous ligament, eliciting pain that was greater than baseline and recovery (p<0.001). Although there was no overall main effect of the nociceptive stimulation (i.e. pain) on λ when the whole group was included in the statistical model (p=0.564), when data were considered separately for those with high and low PC, two distinct and well established responses to the pain were observed. Specifically, those with high PC tightened their control (i.e. stabilized), whereas those with low PC loosened their control (i.e. destabilized). This study provides evidence that individuals' beliefs and attitudes towards pain are related to individual-specific motor behaviors, and suggests that future research studying spine control/stability and LBP should account for these variables.
[Mh] Termos MeSH primário: Catastrofização
Dor Lombar/psicologia
Coluna Vertebral/fisiopatologia
[Mh] Termos MeSH secundário: Adolescente
Adulto
Fenômenos Biomecânicos
Feminino
Seres Humanos
Dor Lombar/fisiopatologia
Masculino
Movimento
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1711
[Cu] Atualização por classe:180120
[Lr] Data última revisão:
180120
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170503
[St] Status:MEDLINE


  10 / 21203 MEDLINE  
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[PMID]:29310386
[Au] Autor:Guo Z; Wang W; Gao WS; Gao F; Wang H; Ding WY
[Ad] Endereço:Department of Spine Surgery, the Third Hospital of Hebei Medical University, Shijiazhuang.
[Ti] Título:Comparison the clinical outcomes and complications of high-viscosity versus low-viscosity in osteoporotic vertebral compression fractures.
[So] Source:Medicine (Baltimore);96(48):e8936, 2017 Dec.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:To compare the clinical outcomes and complications of high viscosity and low viscosity bone cement percutaneous vertebroplasty (PVP) for osteoporotic vertebral compression fractures (OVCF).From September 2009 to September 2015, 100 patients with OVCF were randomly divided into 2 groups: group H, using high viscosity cement (n = 50) or group L, using low viscosity cement (n = 50). The clinical outcomes were assessed by the visual analog scale (VAS), Oswestry Disability Index (ODI), kyphosis Cobb angle, vertebral height, and complications.Significant improvements in the VAS, ODI, kyphosis Cobb angle, and vertebral height were noted in both groups, and the VAS score in the H group showed greater benefit than in the L group. Cement leakage was observed less in group H. Postoperative assessment using computed tomography identified cement leakage in 27 of 98 (27.6%) vertebrae in group H and in 63 of 86 (73.3%) vertebrae in group L (P = .025).Compared with PVP using low viscosity bone cement, PVP using high viscosity bone cement can provide the same clinical outcomes with fewer complications and is recommended for routine clinical use.
[Mh] Termos MeSH primário: Cimentos para Ossos/uso terapêutico
Fraturas por Compressão/cirurgia
Fraturas por Osteoporose/cirurgia
Coluna Vertebral/cirurgia
Vertebroplastia
[Mh] Termos MeSH secundário: Idoso
Idoso de 80 Anos ou mais
Cimentos para Ossos/química
Avaliação da Deficiência
Feminino
Seguimentos
Seres Humanos
Masculino
Meia-Idade
Complicações Pós-Operatórias
Resultado do Tratamento
Viscosidade
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Bone Cements)
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180116
[Lr] Data última revisão:
180116
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180110
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000008936



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