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[PMID]:28461107
[Au] Autor:Gertel S; Mahagna H; Karmon G; Watad A; Amital H
[Ad] Endereço:Zabludowicz Center For Autoimmune Diseases, Sheba Medical Center, Tel-Hashomer 5262100, Israel; Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv 6997801, Israel. Electronic address: smadar.gertel@sheba.health.gov.il.
[Ti] Título:Tofacitinib attenuates arthritis manifestations and reduces the pathogenic CD4 T cells in adjuvant arthritis rats.
[So] Source:Clin Immunol;184:77-81, 2017 11.
[Is] ISSN:1521-7035
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Rheumatoid arthritis (RA) is an autoimmune disease characterized by pronounced inflammation and leukocyte infiltration in affected joints. Tofacitinib is new agent, a selective inhibitor of Janus kinase (JAK) signaling pathways mediated by JAK1 and JAK3 and inhibits the key transcription factors STAT1 and STAT3. We investigated the action mechanisms of tofacitinib in rats with adjuvant-induced-arthritis (AIA). AIA-rats were treated orally with tofacitinib or with methotrexate. Arthritis severity and serum C-reactive protein (CRP) levels were evaluated, splenic cells were examined by flow cytometry and cytokines were analyzed by real-time PCR. Tofacitinib markedly reduced the clinical status of treated rats in comparison to control group. Reduced joints inflammation and down-regulated serum CRP levels reflected the clinical manifestations of the treated rats. Tofacitinib down-regulated significantly the frequency of CD4 IFN-γ T cells and reduced IL-1ß mRNA expression levels in the spleen of the treated rats. These results show that tofacitinib attenuated arthritis severity, modified splenic populations and cytokine imbalance.
[Mh] Termos MeSH primário: Artrite Experimental/imunologia
Artrite Reumatoide/imunologia
Linfócitos T CD4-Positivos/efeitos dos fármacos
Articulações do Pé/efeitos dos fármacos
Piperidinas/farmacologia
Inibidores de Proteínas Quinases/farmacologia
Pirimidinas/farmacologia
Pirróis/farmacologia
[Mh] Termos MeSH secundário: Animais
Antirreumáticos/farmacologia
Artrite Experimental/fisiopatologia
Artrite Reumatoide/fisiopatologia
Proteína C-Reativa/efeitos dos fármacos
Proteína C-Reativa/imunologia
Linfócitos T CD4-Positivos/imunologia

Articulações do Pé/patologia
Membro Anterior
Membro Posterior
Interferon gama/imunologia
Interleucina-1beta/efeitos dos fármacos
Interleucina-1beta/genética
Metotrexato/farmacologia
RNA Mensageiro/efeitos dos fármacos
RNA Mensageiro/metabolismo
Ratos
Reação em Cadeia da Polimerase em Tempo Real
Reação em Cadeia da Polimerase Via Transcriptase Reversa
Baço/citologia
Baço/efeitos dos fármacos
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Antirheumatic Agents); 0 (IL1B protein, rat); 0 (Interleukin-1beta); 0 (Piperidines); 0 (Protein Kinase Inhibitors); 0 (Pyrimidines); 0 (Pyrroles); 0 (RNA, Messenger); 82115-62-6 (Interferon-gamma); 87LA6FU830 (tofacitinib); 9007-41-4 (C-Reactive Protein); YL5FZ2Y5U1 (Methotrexate)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:180206
[Lr] Data última revisão:
180206
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170503
[St] Status:MEDLINE


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[PMID]:28850582
[Au] Autor:Ebina K; Hirao M; Takagi K; Ueno S; Morimoto T; Matsuoka H; Kitaguchi K; Iwahashi T; Hashimoto J; Yoshikawa H
[Ad] Endereço:Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
[Ti] Título:Comparison of the effects of forefoot joint-preserving arthroplasty and resection-replacement arthroplasty on walking plantar pressure distribution and patient-based outcomes in patients with rheumatoid arthritis.
[So] Source:PLoS One;12(8):e0183805, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:PURPOSE: The purpose of this retrospective study is to clarify the difference in plantar pressure distribution during walking and related patient-based outcomes between forefoot joint-preserving arthroplasty and resection-replacement arthroplasty in patients with rheumatoid arthritis (RA). METHODS: Four groups of patients were recruited. Group1 included 22 feet of 11 healthy controls (age 48.6 years), Group2 included 36 feet of 28 RA patients with deformed non-operated feet (age 64.8 years, Disease activity score assessing 28 joints with CRP [DAS28-CRP] 2.3), Group3 included 27 feet of 20 RA patients with metatarsal head resection-replacement arthroplasty (age 60.7 years, post-operative duration 5.6 years, DAS28-CRP 2.4), and Group4 included 34 feet of 29 RA patients with metatarsophalangeal (MTP) joint-preserving arthroplasty (age 64.6 years, post-operative duration 3.2 years, DAS28-CRP 2.3). Patients were cross-sectionally examined by F-SCAN II to evaluate walking plantar pressure, and the self-administered foot evaluation questionnaire (SAFE-Q). Twenty joint-preserving arthroplasty feet were longitudinally examined at both pre- and post-operation. RESULTS: In the 1st MTP joint, Group4 showed higher pressure distribution (13.7%) than Group2 (8.0%) and Group3 (6.7%) (P<0.001). In the 2nd-3rd MTP joint, Group4 showed lower pressure distribution (9.0%) than Group2 (14.5%) (P<0.001) and Group3 (11.5%) (P<0.05). On longitudinal analysis, Group4 showed increased 1st MTP joint pressure (8.5% vs. 14.7%; P<0.001) and decreased 2nd-3rd MTP joint pressure (15.2% vs. 10.7%; P<0.01) distribution. In the SAFE-Q subscale scores, Group4 showed higher scores than Group3 in pain and pain-related scores (84.1 vs. 71.7; P<0.01) and in shoe-related scores (62.5 vs. 43.1; P<0.01). CONCLUSIONS: Joint-preserving arthroplasty resulted in higher 1st MTP joint and lower 2nd-3rd MTP joint pressures than resection-replacement arthroplasty, which were associated with better patient-based outcomes.
[Mh] Termos MeSH primário: Artrite Reumatoide/cirurgia
Artroplastia/métodos
Articulações do Pé/cirurgia
Antepé Humano/cirurgia
Caminhada/fisiologia
[Mh] Termos MeSH secundário: Adulto
Idoso
Artrite Reumatoide/diagnóstico por imagem
Artrite Reumatoide/fisiopatologia
Feminino
Articulações do Pé/diagnóstico por imagem
Articulações do Pé/fisiopatologia
Antepé Humano/diagnóstico por imagem
Antepé Humano/fisiopatologia
Seres Humanos
Masculino
Meia-Idade
Medição da Dor
Pressão
Radiografia
Estudos Retrospectivos
Sapatos
Resultado do Tratamento
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171019
[Lr] Data última revisão:
171019
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170830
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0183805


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[PMID]:28594068
[Au] Autor:Holowka NB; O'Neill MC; Thompson NE; Demes B
[Ad] Endereço:Department of Human Evolutionary Biology, Harvard University, Cambridge, Massachusetts, 02138.
[Ti] Título:Chimpanzee ankle and foot joint kinematics: Arboreal versus terrestrial locomotion.
[So] Source:Am J Phys Anthropol;164(1):131-147, 2017 Sep.
[Is] ISSN:1096-8644
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVES: Many aspects of chimpanzee ankle and midfoot joint morphology are believed to reflect adaptations for arboreal locomotion. However, terrestrial travel also constitutes a significant component of chimpanzee locomotion, complicating functional interpretations of chimpanzee and fossil hominin foot morphology. Here we tested hypotheses of foot motion and, in keeping with general assumptions, we predicted that chimpanzees would use greater ankle and midfoot joint ranges of motion during travel on arboreal supports than on the ground. METHODS: We used a high-speed motion capture system to measure three-dimensional kinematics of the ankle and midfoot joints in two male chimpanzees during three locomotor modes: terrestrial quadrupedalism on a flat runway, arboreal quadrupedalism on a horizontally oriented tree trunk, and climbing on a vertically oriented tree trunk. RESULTS: Chimpanzees used relatively high ankle joint dorsiflexion angles during all three locomotor modes, although dorsiflexion was greatest in arboreal modes. They used higher subtalar joint coronal plane ranges of motion during terrestrial and arboreal quadrupedalism than during climbing, due in part to their use of high eversion angles in the former. Finally, they used high midfoot inversion angles during arboreal locomotor modes, but used similar midfoot sagittal plane kinematics across all locomotor modes. DISCUSSION: The results indicate that chimpanzees use large ranges of motion at their various ankle and midfoot joints during both terrestrial and arboreal locomotion. Therefore, we argue that chimpanzee foot anatomy enables a versatile locomotor repertoire, and urge caution when using foot joint morphology to reconstruct arboreal behavior in fossil hominins.
[Mh] Termos MeSH primário: Articulação do Tornozelo/fisiologia
Fenômenos Biomecânicos/fisiologia
Articulações do Pé/fisiologia
Locomoção/fisiologia
Pan troglodytes/fisiologia
[Mh] Termos MeSH secundário: Animais
Articulação do Tornozelo/anatomia & histologia
Antropologia Física
Evolução Biológica
Articulações do Pé/anatomia & histologia
Seres Humanos
Masculino
Pan troglodytes/anatomia & histologia
Gravação em Vídeo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170911
[Lr] Data última revisão:
170911
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170609
[St] Status:MEDLINE
[do] DOI:10.1002/ajpa.23262


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[PMID]:28521518
[Au] Autor:Sanchis-Sales E; Sancho-Bru JL; Roda-Sales A; Pascual-Huerta J
[Ad] Endereço:a Department de Podologia , Universitat de València , València , Spain.
[Ti] Título:3D characterisation of the dynamics of foot joints of adults during walking. Gait pattern identification.
[So] Source:Comput Methods Biomech Biomed Engin;20(9):1015-1030, 2017 Jul.
[Is] ISSN:1476-8259
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:A detailed description of the kinematics and kinetics of the ankle, midtarsal and metatarsophalangeal joints of the feet of a healthy adult male population during barefoot walking is provided. Plots of the angles and moments in each plane during the stance phase are reported, along with the mean and standard deviation values of 87 different parameters that characterise the 3D dynamics of the foot joints. These parameters were used to check for similarities between subjects through a hierarchical analysis that allowed three different gait patterns to be identified, most of the differences corresponding to the frontal and transverse planes.
[Mh] Termos MeSH primário: Articulações do Pé/fisiologia
Marcha/fisiologia
Imagem Tridimensional
[Mh] Termos MeSH secundário: Adulto
Fenômenos Biomecânicos
Análise por Conglomerados
Marcadores Fiduciais
Seres Humanos
Masculino
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171106
[Lr] Data última revisão:
171106
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170520
[St] Status:MEDLINE
[do] DOI:10.1080/10255842.2017.1331343


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[PMID]:28399893
[Au] Autor:Peters SE; Laxer RM; Connolly BL; Parra DA
[Ad] Endereço:School of Medicine and Medical Sciences, University College Dublin, Dublin, Ireland.
[Ti] Título:Ultrasound-guided steroid tendon sheath injections in juvenile idiopathic arthritis: a 10-year single-center retrospective study.
[So] Source:Pediatr Rheumatol Online J;15(1):22, 2017 Apr 11.
[Is] ISSN:1546-0096
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: The aims of this study were to: (a) Identify tendon sheaths most commonly treated with steroid injections in a pediatric patient population with Juvenile Idiopathic Arthritis (JIA); (b) Describe technical aspects of the procedure; (c) Characterize sonographic appearance of tenosynovitis in JIA; (d) Assess agreement between clinical request and sites injected. METHODS: This was a 10 year single-center retrospective study (May 2006-April 2016) of patients with JIA referred by Rheumatology for ultrasound-guided tendon sheath injections. Patient demographics, clinical referral information, sonographic appearance of the tendon sheaths and technical aspects of the procedure were analyzed. RESULTS: There were 308 procedures of 244 patients (75% female, mean age 9.6 years) who underwent a total of 926 tendon sheath injections. Ankle tendons were most commonly injected (84.9%), specifically the tendon sheaths of tibialis posterior (22.3%), peroneus longus (20%) and brevis (19.7%). The majority of treated sites (91.9%) showed peritendinous fluid and sheath thickening on ultrasound. There were 2 minor intra-procedure complications without sequelae. A good agreement between clinical request and sites injected was observed. CONCLUSIONS: Ultrasound-guided tendon sheath injections with steroids are used frequently to treat patients with JIA. It is a safe intervention with a high technical success rate. The ankle region, specifically the medial compartment, is the site most commonly injected in this group of patients. The most common sonographic finding is peritendinous fluid and sheath thickening. These findings might assist clinicians and radiologists to characterize and more effectively manage tenosynovitis in patients with JIA.
[Mh] Termos MeSH primário: Anti-Inflamatórios/uso terapêutico
Artrite Juvenil/tratamento farmacológico
Tendões
Tenossinovite/tratamento farmacológico
Triancinolona Acetonida/análogos & derivados
[Mh] Termos MeSH secundário: Adolescente
Articulação do Tornozelo/diagnóstico por imagem
Artrite Juvenil/diagnóstico por imagem
Criança
Pré-Escolar
Feminino
Articulações do Pé
Articulação da Mão
Seres Humanos
Lactente
Injeções
Injeções Intra-Articulares
Masculino
Estudos Retrospectivos
Tenossinovite/diagnóstico por imagem
Triancinolona Acetonida/uso terapêutico
Ultrassonografia
Articulação do Punho
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anti-Inflammatory Agents); F446C597KA (Triamcinolone Acetonide); I7GT1U99Y9 (triamcinolone hexacetonide)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170816
[Lr] Data última revisão:
170816
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170413
[St] Status:MEDLINE
[do] DOI:10.1186/s12969-017-0155-3


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[PMID]:28389554
[Au] Autor:Sakellariou G; Conaghan PG; Zhang W; Bijlsma JWJ; Boyesen P; D'Agostino MA; Doherty M; Fodor D; Kloppenburg M; Miese F; Naredo E; Porcheret M; Iagnocco A
[Ad] Endereço:Division of Rheumatology, IRCCS Policlinico San Matteo Foundation, University of Pavia, Pavia, Italy.
[Ti] Título:EULAR recommendations for the use of imaging in the clinical management of peripheral joint osteoarthritis.
[So] Source:Ann Rheum Dis;76(9):1484-1494, 2017 Sep.
[Is] ISSN:1468-2060
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:The increased information provided by modern imaging has led to its more extensive use. Our aim was to develop evidence-based recommendations for the use of imaging in the clinical management of the most common arthropathy, osteoarthritis (OA). A task force (including rheumatologists, radiologists, methodologists, primary care doctors and patients) from nine countries defined 10 questions on the role of imaging in OA to support a systematic literature review (SLR). Joints of interest were the knee, hip, hand and foot; imaging modalities included conventional radiography (CR), MRI, ultrasonography, CT and nuclear medicine. PubMed and EMBASE were searched. The evidence was presented to the task force who subsequently developed the recommendations. The strength of agreement for each recommendation was assessed. 17 011 references were identified from which 390 studies were included in the SLR. Seven recommendations were produced, covering the lack of need for diagnostic imaging in patients with typical symptoms; the role of imaging in differential diagnosis; the lack of benefit in monitoring when no therapeutic modification is related, though consideration is required when unexpected clinical deterioration occurs; CR as the first-choice imaging modality; consideration of how to correctly acquire images and the role of imaging in guiding local injections. Recommendations for future research were also developed based on gaps in evidence, such as the use of imaging in identifying therapeutic targets, and demonstrating the added value of imaging. These evidence-based recommendations and related research agenda provide the basis for sensible use of imaging in routine clinical assessment of people with OA.
[Mh] Termos MeSH primário: Articulações do Pé/diagnóstico por imagem
Articulação da Mão/diagnóstico por imagem
Articulação do Quadril/diagnóstico por imagem
Articulação do Joelho/diagnóstico por imagem
Osteoartrite do Quadril/diagnóstico por imagem
Osteoartrite do Joelho/diagnóstico por imagem
[Mh] Termos MeSH secundário: Comitês Consultivos
Europa (Continente)
Seres Humanos
Imagem por Ressonância Magnética
Osteoartrite/diagnóstico por imagem
Radiografia
Cintilografia
Reumatologia
Tomografia Computadorizada por Raios X
Ultrassonografia
[Pt] Tipo de publicação:JOURNAL ARTICLE; PRACTICE GUIDELINE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170821
[Lr] Data última revisão:
170821
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170409
[St] Status:MEDLINE
[do] DOI:10.1136/annrheumdis-2016-210815


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[PMID]:28371497
[Au] Autor:Feng P; Li YX; Li J; Ouyang XY; Deng W; Chen Y; Zhang H
[Ad] Endereço:Department of Orthopaedics, West China Hospital, Sichuan University, Chengdu, China.
[Ti] Título:Staged Management of Missed Lisfranc Injuries: A Report of Short-term Results.
[So] Source:Orthop Surg;9(1):54-61, 2017 Feb.
[Is] ISSN:1757-7861
[Cp] País de publicação:Australia
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: Lisfranc joint injury is a rare injury and can be easily missed at the initial treatment. Once ignored, late reduction is very difficult and requires extensive dissection. Surgical outcome is not as good as in the case of an early reduction. The aim of this cohort study was to analyze the midterm clinical and radiographic outcomes of staged reduction and fixation in a consecutive series of patients with old Lisfranc injuries. METHODS: Fifteen patients (16 feet) with missed Lisfranc injuries were treated with staged reduction. Mean duration between injury and surgery was 4.8 months (3-8 months). In the first stage, an external fixator was applied across the Lisfranc joint or/and Chopart joint and distraction was done at 1-2 mm/day. In the second staged, open reduction and internal fixation (ORIF) were done and we were able to reduce all the fractures and dislocations. RESULTS: The mean duration between two surgeries was 3.2 weeks (range, 2.5-4.5 weeks). Anatomic reduction was obtained in all 15 patients. At the last follow-up point, 7 feet had good functional results, 5 feet fair, and 4 feet poor functional results. In the 4 patients who achieved poor functional results, 2 cases were due to severe injuries to the articular surface and tissue scaring; 2 cases were due to loss of reduction. For the 4 feet with poor functional results, 2 were scheduled for secondary arthrodesis during the follow-up. The average American Orthopaedic Foot and Ankle Society Midfoot Scale (AOFAS) scores for these patients were 75.8 points (range, 43-98 points). The pain visual analog scale (VAS) was 3.1 points at the final follow-up. CONCLUSION: Our study demonstrated that staged reduction and extra-articular fixation should be considered for old Lisfranc injuries with a good reduction, firm stability, and low risk of intraoperative fracture and soft tissue complications.
[Mh] Termos MeSH primário: Articulações do Pé/cirurgia
Fraturas Ósseas/cirurgia
[Mh] Termos MeSH secundário: Adulto
Fixadores Externos
Articulações do Pé/diagnóstico por imagem
Articulações do Pé/fisiopatologia
Fixação Interna de Fraturas/efeitos adversos
Fixação Interna de Fraturas/métodos
Fraturas Ósseas/diagnóstico por imagem
Seres Humanos
Meia-Idade
Osteogênese por Distração/efeitos adversos
Osteogênese por Distração/métodos
Cuidados Pós-Operatórios/métodos
Radiografia
Recuperação de Função Fisiológica
Sistema de Registros
Estudos Retrospectivos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171016
[Lr] Data última revisão:
171016
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170404
[St] Status:MEDLINE
[do] DOI:10.1111/os.12320


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[PMID]:28276650
[Au] Autor:Qiao YS; Li JK; Shen H; Bao HY; Jiang M; Liu Y; Kapadia W; Zhang HT; Yang HL
[Ad] Endereço:Department of Orthopaedics, the First Affiliated Hospital of Soochow University, Soochow, China.
[Ti] Título:Comparison of Arthrodesis and Non-fusion to Treat Lisfranc Injuries.
[So] Source:Orthop Surg;9(1):62-68, 2017 Feb.
[Is] ISSN:1757-7861
[Cp] País de publicação:Australia
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: "Lisfranc joint injury" is comprised of a tarsometatarsal joint-complex injury. The Lisfranc complex injury is always a challenge for orthopedists, and the optimum treatment is still up for debate. Anatomic reduction and stable internal fixation prove to have no satisfactory outcomes. This research aims to compare the clinical curative effects, complications and radiographic features of arthrodesis and non-fusion of the Lisfranc joint in the follow-up of the patients who suffered Lisfranc injuries. METHODS: A comparative retrospective study of 25 patients with acute or subacute Lisfranc complex injuries was conducted between September 2013 and March 2015 in the First Affiliated Hospital of Soochow University. All patients were classified by Myerson classification. Eight patients were treated with arthrodesis, while 17 patients received non-fusion operations. The clinical curative effects, complications and image differences were compared between the two groups. American Orthopaedic Foot and Ankle Society (AOFAS) hindfoot score, Short Form-36 (SF-36) and Visual Analogue Scale (VAS) score were evaluated for each patient during the follow-up. All statistics were analyzed using the SPSS software system. RESULTS: All fractures healed for both the arthrodesis group and the non-fusion group. Patients in the arthrodesis group had a higher AOFAS score compared with patients in the non-fusion group (94.00 vs. 88.58, P = 0.034). Complications occurred in eight patients (8/17, 47%) in the non-arthrodesis group, including the second and third phalanx abduction (1), talipes cavus (2), eversion deformity of front foot (3), eversion deformity of calcaneus (1), as well as postoperative infection (1). Only two patients (2/8, 25%) in the arthrodesis group suffered complications. One was a limitation of motion of the front foot and pain during walking; the other was an eversion deformity of front foot. CONCLUSION: Primary arthrodesis has advantages compared to primary open reduction and internal fixation (ORIF): reduced foot deformity rates, sustained biomechanical morphology of the feet, reduced complications, higher level of function recovery, shorter time of surgical procedures, fewer complications, higher AOFAS score and fewer frequency of complications. According to our research, primary arthrodesis may be a better choice for treating Lisfranc injury.
[Mh] Termos MeSH primário: Artrodese/métodos
Articulações do Pé/cirurgia
Fraturas Ósseas/cirurgia
[Mh] Termos MeSH secundário: Adolescente
Adulto
Idoso
Artrodese/efeitos adversos
Feminino
Articulações do Pé/diagnóstico por imagem
Articulações do Pé/lesões
Fixação Interna de Fraturas/métodos
Consolidação da Fratura
Fraturas Ósseas/diagnóstico por imagem
Seres Humanos
Masculino
Meia-Idade
Dor Pós-Operatória
Cuidados Pós-Operatórios/métodos
Radiografia
Estudos Retrospectivos
Tomografia Computadorizada por Raios X
Adulto Jovem
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171016
[Lr] Data última revisão:
171016
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170310
[St] Status:MEDLINE
[do] DOI:10.1111/os.12316


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[PMID]:28229810
[Au] Autor:Iagnocco A; Naredo E
[Ad] Endereço:Dipartimento Scienze Cliniche e Biologiche, Reumatologia, Università degli Studi di Torino, Italy. annamaria.iagnocco1@gmail.com.
[Ti] Título:Ultrasound of the osteoarthritic joint.
[So] Source:Clin Exp Rheumatol;35(3):527-534, 2017 May-Jun.
[Is] ISSN:0392-856X
[Cp] País de publicação:Italy
[La] Idioma:eng
[Ab] Resumo:Ultrasound (US) has acquired an increasing role in the assessment of joint and periarticular abnormalities in osteoarthritis (OA). It is able to image a large set of abnormalities in this disease which include both inflammatory and structural changes at different peripheral joint sites and it is helpful in guiding local procedures that can be easily and safely performed with optimal patient's tolerance. US is a feasible imaging modality that has become a bedside procedure in the rheumatology clinical practice, thus filling the gap between clinical and radiographic evaluations of patients with OA. The present review focuses and summarises the currently available data on the applications of US in OA.
[Mh] Termos MeSH primário: Articulações/diagnóstico por imagem
Osteoartrite do Quadril/diagnóstico por imagem
Osteoartrite do Joelho/diagnóstico por imagem
Ultrassonografia
[Mh] Termos MeSH secundário: Fenômenos Biomecânicos
Articulações do Pé/diagnóstico por imagem
Articulações do Pé/fisiopatologia
Articulação da Mão/diagnóstico por imagem
Articulação da Mão/fisiopatologia
Articulação do Quadril/diagnóstico por imagem
Articulação do Quadril/fisiopatologia
Seres Humanos
Articulações/fisiopatologia
Articulação do Joelho/diagnóstico por imagem
Articulação do Joelho/fisiopatologia
Osteoartrite do Quadril/fisiopatologia
Osteoartrite do Joelho/fisiopatologia
Valor Preditivo dos Testes
Prognóstico
Índice de Gravidade de Doença
Articulação do Ombro/diagnóstico por imagem
Articulação do Ombro/fisiopatologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170824
[Lr] Data última revisão:
170824
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170224
[St] Status:MEDLINE


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[PMID]:28222170
[Au] Autor:Simons P; Sommerer T; Zderic I; Wahl D; Lenz M; Skulev H; Knobe M; Gueorguiev B; Richards RG; Klos K
[Ad] Endereço:Department of Foot and Ankle Surgery, Catholic Clinic Mainz, Mainz, Germany.
[Ti] Título:Biomechanical investigation of two plating systems for medial column fusion in foot.
[So] Source:PLoS One;12(2):e0172563, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Arthrodesis of the medial column (navicular, cuneiform I and metatarsal I) is performed for reasons such as Charcot arthropathy, arthritis, posttraumatic reconstruction or severe pes planus. However, the complication rate is still high and mainly resulting from inadequate fixation. Special plates, designed for medial column arthrodesis, seem to offer potential to reduce the complication rate. The aim of this study was to investigate biomechanically plantar and dorsomedial fusion of the medial column using two new plating systems. METHODS: Eight matched pairs of human cadaveric lower legs were randomized in two groups and medial column fusion was performed using either plantar or dorsomedial variable-angle locking compression plates. The specimens were biomechanically tested under cyclic progressively increasing axial loading with physiological profile of each cycle. In addition to the machine data, mediolateral x-rays were taken every 250 cycles and motion tracking was performed to determine movements at the arthrodesis site. Statistical analysis of the parameters of interest was performed at a level of significance p = 0.05. RESULTS: Displacement of the talo-navicular joint after 1000, 2000 and 4000 cycles was significantly lower for plantar plating (p≤0.039) while there was significantly less movement in the naviculo-cuneiform I joint for dorsal plating post these cycle numbers (p<0.001). Displacements in all three joints of the medial column, as well as angular and torsional deformations between the navicular and metatarsal I increased significantly for each plating technique between 1000, 2000 and 4000 cycles (p≤0.021). The two plating systems did not differ significantly with regard to stiffness and cycles to failure (p≥0.171). CONCLUSION: From biomechanical point of view, although dorsomedial plating showed less movement than plantar plating in the current setup under dynamic loading, there was no significant difference between the two plating systems with regard to stiffness and cycles to failure. Both tested techniques for dorsomedial and plantar plating appear to be applicable for arthrodesis of the medial column of the foot and other considerations, such as access morbidity, associated deformities or surgeon's preference, may also guide the choice of plating pattern. Further clinical studies are necessary before definitive recommendations can be given.
[Mh] Termos MeSH primário: Artrodese/instrumentação
Placas Ósseas
Articulações do Pé/cirurgia
Ossos do Metatarso/cirurgia
Ossos do Tarso/cirurgia
Suporte de Carga
[Mh] Termos MeSH secundário: Idoso
Idoso de 80 Anos ou mais
Artrodese/métodos
Fenômenos Biomecânicos
Cadáver
Falha de Equipamento
Feminino
Articulações do Pé/diagnóstico por imagem
Seres Humanos
Masculino
Ossos do Metatarso/diagnóstico por imagem
Meia-Idade
Movimento (Física)
Distribuição Aleatória
Ossos do Tarso/diagnóstico por imagem
[Pt] Tipo de publicação:EVALUATION STUDIES; JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170222
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0172563



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