Base de dados : MEDLINE
Pesquisa : A02.880 [Categoria DeCS]
Referências encontradas : 22002 [refinar]
Mostrando: 1 .. 10   no formato [Detalhado]

página 1 de 2201 ir para página                         

  1 / 22002 MEDLINE  
              next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28468849
[Au] Autor:Lyle MA; Nichols TR; Kajtaz E; Maas H
[Ad] Endereço:School of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia mlyle@ap.gatech.edu.
[Ti] Título:Musculotendon adaptations and preservation of spinal reflex pathways following agonist-to-antagonist tendon transfer.
[So] Source:Physiol Rep;5(9), 2017 May.
[Is] ISSN:2051-817X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Tendon transfer surgeries are performed to restore lost motor function, but outcomes are variable, particularly those involving agonist-to-antagonist muscles. Here, we evaluated the possibility that lack of proprioceptive feedback reorganization and musculotendon adaptations could influence outcomes. Plantaris-to-tibialis anterior tendon transfer along with resection of the distal third of the tibialis anterior muscle belly was performed in eight cats. Four cats had concurrent transection of the deep peroneal nerve. After 15-20 weeks, intermuscular length and force-dependent sensory feedback were examined between hindlimb muscles, and the integrity of the tendon-to-tendon connection and musculotendon adaptations were evaluated. Three of the transferred tendons tore. A common finding was the formation of new tendinous connections, which often inserted near the original location of insertion on the skeleton (e.g., connections from plantaris toward calcaneus and from tibialis anterior toward first metatarsal). The newly formed tissue connections are expected to compromise the mechanical action of the transferred muscle. We found no evidence of changes in intermuscular reflexes between transferred plantaris muscle and synergists/antagonists whether the tendon-to-tendon connection remained intact or tore, indicating no spinal reflex reorganization. We propose the lack of spinal reflex reorganization could contribute the transferred muscle not adopting the activation patterns of the host muscle. Taken together, these findings suggest that musculotendon plasticity and lack of spinal reflex circuitry reorganization could limit functional outcomes after tendon transfer surgery. Surgical planning and outcomes assessments after tendon transfer surgery should consider potential consequences of the transferred muscle's intermuscular spinal circuit actions.
[Mh] Termos MeSH primário: Retroalimentação Fisiológica
Músculo Esquelético/fisiologia
Reflexo
Medula Espinal/fisiologia
Tendões/fisiologia
[Mh] Termos MeSH secundário: Animais
Gatos
Vias Eferentes/fisiologia
Feminino
Músculo Esquelético/inervação
Nervo Fibular/fisiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180305
[Lr] Data última revisão:
180305
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170505
[St] Status:MEDLINE


  2 / 22002 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:29227993
[Au] Autor:McGurk PD; Swartz ME; Chen JW; Galloway JL; Eberhart JK
[Ad] Endereço:Department of Molecular Biosciences, University of Texas at Austin, Austin, TX, United States of America.
[Ti] Título:In vivo zebrafish morphogenesis shows Cyp26b1 promotes tendon condensation and musculoskeletal patterning in the embryonic jaw.
[So] Source:PLoS Genet;13(12):e1007112, 2017 12.
[Is] ISSN:1553-7404
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Integrated development of diverse tissues gives rise to a functional, mobile vertebrate musculoskeletal system. However, the genetics and cellular interactions that drive the integration of muscle, tendon, and skeleton are poorly understood. In the vertebrate head, neural crest cells, from which cranial tendons derive, pattern developing muscles just as tendons have been shown to in limb and trunk tissue, yet the mechanisms of this patterning are unknown. From a forward genetic screen, we determined that cyp26b1 is critical for musculoskeletal integration in the ventral pharyngeal arches, particularly in the mandibulohyoid junction where first and second arch muscles interconnect. Using time-lapse confocal analyses, we detail musculoskeletal integration in wild-type and cyp26b1 mutant zebrafish. In wild-type fish, tenoblasts are present in apposition to elongating muscles and condense in discrete muscle attachment sites. In the absence of cyp26b1, tenoblasts are generated in normal numbers but fail to condense into nascent tendons within the ventral arches and, subsequently, muscles project into ectopic locales. These ectopic muscle fibers eventually associate with ectopic tendon marker expression. Genetic mosaic analysis demonstrates that neural crest cells require Cyp26b1 function for proper musculoskeletal development. Using an inhibitor, we find that Cyp26 function is required in a short time window that overlaps the dynamic window of tenoblast condensation. However, cyp26b1 expression is largely restricted to regions between tenoblast condensations during this time. Our results suggest that degradation of RA by this previously undescribed population of neural crest cells is critical to promote condensation of adjacent scxa-expressing tenoblasts and that these condensations are subsequently required for proper musculoskeletal integration.
[Mh] Termos MeSH primário: Desenvolvimento Embrionário/genética
Desenvolvimento Maxilofacial/genética
Morfogênese/genética
Ácido Retinoico 4 Hidroxilase/genética
[Mh] Termos MeSH secundário: Animais
Padronização Corporal/genética
Regulação da Expressão Gênica no Desenvolvimento
Arcada Osseodentária/embriologia
Desenvolvimento Muscular/genética
Músculo Esquelético/embriologia
Músculo Esquelético/metabolismo
Tendões/embriologia
Tendões/crescimento & desenvolvimento
Peixe-Zebra/embriologia
Peixe-Zebra/genética
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL
[Nm] Nome de substância:
EC 1.14.14.1 (Retinoic Acid 4-Hydroxylase)
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180305
[Lr] Data última revisão:
180305
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171212
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pgen.1007112


  3 / 22002 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:29246992
[Au] Autor:Berner D
[Ad] Endereço:Department of Clinical Science & Services, Royal Veterinary College, Hawkshead Lane, North Mymms, Hatfield, Hertfordshire AL9 7TA, UK.
[Ti] Título:Diagnostic imaging of tendinopathies of the superficial flexor tendon in horses.
[So] Source:Vet Rec;181(24):652-654, 2017 12 16.
[Is] ISSN:2042-7670
[Cp] País de publicação:England
[La] Idioma:eng
[Mh] Termos MeSH primário: Tendinopatia
Tendões
[Mh] Termos MeSH secundário: Animais
Diagnóstico por Imagem
Membro Anterior
Doenças dos Cavalos
Cavalos
Traumatismos dos Tendões/veterinária
[Pt] Tipo de publicação:JOURNAL ARTICLE; COMMENT
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180222
[Lr] Data última revisão:
180222
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171217
[St] Status:MEDLINE
[do] DOI:10.1136/vr.j5746


  4 / 22002 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:29384844
[Au] Autor:You JP; Lu L; Li CJ; Ren B; Wang T
[Ad] Endereço:Department of Emergency.
[Ti] Título:Modified trapeziectomy with ligament reconstruction tendon interposition for the treatment of advanced thumb carpometacarpal arthritis: A case report.
[So] Source:Medicine (Baltimore);97(5):e9665, 2018 Feb.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:RATIONALE: Thumb carpometacarpal (CMC) arthritis is a common disease. Various procedures have been described for the treatment of advanced thumb CMC arthritis. This essay shows a CMC arthritis case treated by modified trapeziectomy with ligament reconstruction tendon interposition (LRTI). PATIENT CONCERNS: A 53-year-old Chinese female complained of pain and swelling at the base of the left thumb for 10 years. Visual analog scale (VAS) for thumb was 7 points, Disabilities of Arm, Shoulder and Hand (DASH) score was 51 points, and Kapandji score was 6 points before surgery. Preoperative range of motion (ROM) for radial abduction and volar abduction were 63°and 62°, respectively. Grip power was 15.3 kg and key-pinch power was 1.8 kg before operation. Preoperative waist flexion power was 20.9 kg. Hand x-ray showed left thumb CMC arthritis in Eaton stage III and the height of the trapezial space was 10 mm. DIAGNOSES: She was diagnosed with left thumb CMC arthritis (Eaton III stage). INTERVENTIONS: The patient underwent modified trapeziectomy with LRTI. After exposing and removing trapezium, and a hole from the dorsal base to the center of the articular surface was drilled. Then we cut the whole flexor carpi radialis and divided it into 2 halves. Afterward, we passed one-half through the hole and tied it to the other part and sutured them. The rest tendon was then tied continuously and sutured. Then we rolled it up into the space where previous trapezium was located. OUTCOMES: Two years after operation, pain and swelling relieved and no recurrence of the clinical symptoms occurred. VAS, DASH, and Kapandji score were 2, 22, 7 points, respectively. ROM for radial abduction and volar abduction were 79° and 78°, respectively. Furthermore, grip power was 22.7 kg and key-pinch power was 3.8 kg. Waist flexion power was 20.0 kg. Hand x-ray showed that the height of the trapezial space was 9.8 mm. LESSONS: Modified trapeziectomy with LRTI in treatment of advanced thumb CMC arthritis had a satisfactory efficacy. This new procedure not only prevents thumb sinking, but also provides enough support for thumb.
[Mh] Termos MeSH primário: Articulações Carpometacarpais
Ligamentos/cirurgia
Osteoartrite/cirurgia
Procedimentos Cirúrgicos Reconstrutivos
Tendões/cirurgia
Trapézio/cirurgia
[Mh] Termos MeSH secundário: Articulações Carpometacarpais/diagnóstico por imagem
Articulações Carpometacarpais/cirurgia
Feminino
Seres Humanos
Meia-Idade
Procedimentos Ortopédicos
Osteoartrite/diagnóstico por imagem
Polegar/diagnóstico por imagem
Polegar/cirurgia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180221
[Lr] Data última revisão:
180221
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180201
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000009665


  5 / 22002 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
[PMID]:29182826
[Au] Autor:Bojanic I; Dimnjakovic D; Mahnik A; Smoljanovic T
[Ti] Título:IS THERE ANY ROOM FOR TENDOSCOPY IN THE SURGICAL TREATMENT OF POSTERIOR TIBIAL TENDON INSUFFICIENCY?
[So] Source:Lijec Vjesn;138(5-6):144-151, 2016 May.
[Is] ISSN:0024-3477
[Cp] País de publicação:Croatia
[La] Idioma:eng
[Ab] Resumo:Posterior tibial tendon insufficiency (PTTI) is nowadays considered to be the main cause of adult-acquired flatfoot deformity (AAFD). The purpose of this study is to report the outcomes of tendoscopic treatment of tibialis poste- rior tendon (TP) in eleven patients with stage 1 or 2 PTTI and failed prior conservative treatment. Tendoscopy was carried out as a solitary procedure in 8 patients, while in 3 patients additional procedures such as ,,mini-open" tubularization of TP or anterior ankle arthroscopy were necessary. In a single patient transfer of flexor digitorum longus tendon was performed as a second stage surgery due to complete rupture of TP. Related with tendoscopic procedure, no complications were re- ported. TP tendoscopy is a useful and beneficial minimally invasive procedure to treat TP pathology at earlier stages of PTTI. It is a technically demanding procedure that requires extensive experience in arthroscopic management of small ioints and excellent knowledge of repional anatomy.
[Mh] Termos MeSH primário: Artroscopia/métodos
Disfunção do Tendão Tibial Posterior
Tendões
[Mh] Termos MeSH secundário: Adulto
Tornozelo/diagnóstico por imagem
Tornozelo/cirurgia
Tratamento Conservador/métodos
Croácia
Feminino
Pé Chato/etiologia
Pé Chato/terapia
Seres Humanos
Masculino
Meia-Idade
Procedimentos Cirúrgicos Minimamente Invasivos/métodos
Gravidade do Paciente
Disfunção do Tendão Tibial Posterior/complicações
Disfunção do Tendão Tibial Posterior/diagnóstico
Disfunção do Tendão Tibial Posterior/cirurgia
Tendões/diagnóstico por imagem
Tendões/cirurgia
Resultado do Tratamento
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180208
[Lr] Data última revisão:
180208
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171129
[St] Status:MEDLINE


  6 / 22002 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:29201303
[Au] Autor:Rhee SM; Oh JH
[Ad] Endereço:Department of Orthopedic Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.
[Ti] Título:Bridging Graft in Irreparable Massive Rotator Cuff Tears: Autogenic Biceps Graft versus Allogenic Dermal Patch Graft.
[So] Source:Clin Orthop Surg;9(4):497-505, 2017 Dec.
[Is] ISSN:2005-4408
[Cp] País de publicação:Korea (South)
[La] Idioma:eng
[Ab] Resumo:Background: Few comparative studies have reported on the use of biologic grafts for irreparable massive rotator cuff tears. The purpose of this study was to assess the results of arthroscopic bridging graft in irreparable massive rotator cuff tears using an autogenic long head of biceps tendon (LHBT) or an allogenic dermal patch (ADP). Methods: We retrospectively reviewed 24 patients treated using the LHBT (group I) and eight patients with complete rupture of the LHBT treated using an ADP (group II) since 2011. Preoperative Goutallier's fatty degeneration, range of motion (ROM), visual analogue scale (VAS) for pain, American Shoulder and Elbow Surgeons (ASES) score, and Quick Disabilities of the Arm, Shoulder, and Hand (DASH) score were assessed and healing failure was evaluated at 1 year after surgery by ultrasonography or magnetic resonance imaging. Results: The mean fatty degeneration in groups I and II was 3.9 and 3.6 for the supraspinatus ( = 0.288), 2.7 and 2.9 for the infraspinatus ( = 0.685), 0.9 and 1.3 for the subscapularis ( = 0.314), and 1.3 and 3.0 for the teres minor ( = 0.005), respectively. Subscapularis tears were found in 8 patients (33.3%) in group I and in 7 patients (87.5%) in group II ( = 0.023). Mean ROMs and functional scores improved significantly in group I (forward flexion: 121.7° to 153.3°, = 0.010; external rotation: 32.7° to 52.7°, = 0.001; external rotation at 90°: 63.3° to 74.5°, = 0.031; internal rotation: T10.5 to T9.3, = 0.045; VAS: 7.0 to 1.1, p < 0.001; ASES score: 45.4 to 81.6, = 0.028; and Quick DASH score: 50.0 to 14.2, = 0.017), whereas only VAS showed significant improvement in group II (from 5.9 to 2.0, = 0.025) and ROMs and other functional scores increased without statistical significance in the group. Healing failure was found in 13 patients (54.2%) in group I and in 6 patients (75.0%) in group II ( = 0.404). Conclusions: The surgeon should prudently choose surgical options for irreparable massive rotator cuff tears, especially in patients with severe fatty degeneration in the teres minor or combined biceps and subscapularis tears.
[Mh] Termos MeSH primário: Tecido Adiposo/patologia
Lesões do Manguito Rotador/fisiopatologia
Lesões do Manguito Rotador/cirurgia
Articulação do Ombro/fisiopatologia
Transplante de Pele
Tendões/transplante
[Mh] Termos MeSH secundário: Idoso
Artroscopia
Feminino
Seres Humanos
Imagem por Ressonância Magnética
Masculino
Meia-Idade
Dor Musculoesquelética/etiologia
Amplitude de Movimento Articular
Estudos Retrospectivos
Rotação
Lesões do Manguito Rotador/complicações
Lesões do Manguito Rotador/diagnóstico por imagem
Articulação do Ombro/diagnóstico por imagem
Transplante Autólogo
Transplante Homólogo
Ultrassonografia
Cicatrização
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180207
[Lr] Data última revisão:
180207
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171205
[St] Status:MEDLINE
[do] DOI:10.4055/cios.2017.9.4.497


  7 / 22002 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:29201295
[Au] Autor:Kim YK; Ahn JH; Yoo JD
[Ad] Endereço:Department of Orthopaedic Surgery, Ewha Womans University Mokdong Hospital, Seoul, Korea.
[Ti] Título:A Comparative Study of Clinical Outcomes and Second-Look Arthroscopic Findings between Remnant-Preserving Tibialis Tendon Allograft and Hamstring Tendon Autograft in Anterior Cruciate Ligament Reconstruction: Matched-Pair Design.
[So] Source:Clin Orthop Surg;9(4):424-431, 2017 Dec.
[Is] ISSN:2005-4408
[Cp] País de publicação:Korea (South)
[La] Idioma:eng
[Ab] Resumo:Background: This study aimed to compare stability, functional outcome, and second-look arthroscopic findings after anterior cruciate ligament reconstruction between remnant-preserving tibialis tendon allograft and remnant-sacrificing hamstring tendon autograft. Methods: We matched two groups (remnant-preserving tibialis tendon allograft group and hamstring tendon autograft group) in terms of demographic characteristics, associated injury, and knee characteristics. Each group consisted of 25 patients. Results: Operation time was longer in the remnant-preserving tibialis tendon allograft group, but there was no significant intergroup difference in stability, clinical outcome, and second-look arthroscopic findings. Conclusions: When an autograft is not feasible in anterior cruciate ligament reconstruction, the remnant-preserving technique can produce comparable results in terms of restoration of function, stability of the knee, and degree of synovium coverage at second-look arthroscopy compared to remnant-sacrificing hamstring autograft.
[Mh] Termos MeSH primário: Lesões do Ligamento Cruzado Anterior/cirurgia
Reconstrução do Ligamento Cruzado Anterior/métodos
Instabilidade Articular/etiologia
Articulação do Joelho/cirurgia
Tendões/transplante
[Mh] Termos MeSH secundário: Adolescente
Adulto
Aloenxertos
Lesões do Ligamento Cruzado Anterior/complicações
Reconstrução do Ligamento Cruzado Anterior/efeitos adversos
Artroscopia
Autoenxertos
Feminino
Seres Humanos
Imagem Tridimensional
Instabilidade Articular/diagnóstico por imagem
Articulação do Joelho/diagnóstico por imagem
Articulação do Joelho/fisiopatologia
Escore de Lysholm para Joelho
Masculino
Análise por Pareamento
Meia-Idade
Duração da Cirurgia
Estudos Retrospectivos
Cirurgia de Second-Look
Tomografia Computadorizada por Raios X
Resultado do Tratamento
Adulto Jovem
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180207
[Lr] Data última revisão:
180207
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171205
[St] Status:MEDLINE
[do] DOI:10.4055/cios.2017.9.4.424


  8 / 22002 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:29298298
[Au] Autor:Kuntz LA; Rossetti L; Kunold E; Schmitt A; von Eisenhart-Rothe R; Bausch AR; Burgkart RH
[Ad] Endereço:Klinik für Orthopädie und Sportorthopädie, Klinikum rechts der Isar, Technische Universität München, München, Germany.
[Ti] Título:Biomarkers for tissue engineering of the tendon-bone interface.
[So] Source:PLoS One;13(1):e0189668, 2018.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The tendon-bone interface (enthesis) is a highly sophisticated biomaterial junction that allows stress transfer between mechanically dissimilar materials. The enthesis encounters very high mechanical demands and the regenerative capacity is very low resulting in high rupture recurrence rates after surgery. Tissue engineering offers the potential to recover the functional integrity of entheses. However, recent enthesis tissue engineering approaches have been limited by the lack of knowledge about the cells present at this interface. Here we investigated the cellular differentiation of enthesis cells and compared the cellular pattern of enthesis cells to tendon and cartilage cells in a next generation sequencing transcriptome study. We integrated the transcriptome data with proteome data of a previous study to identify biomarkers of enthesis cell differentiation. Transcriptomics detected 34468 transcripts in total in enthesis, tendon, and cartilage. Transcriptome comparisons revealed 3980 differentially regulated candidates for enthesis and tendon, 395 for enthesis and cartilage, and 946 for cartilage and tendon. An asymmetric distribution of enriched genes was observed in enthesis and cartilage transcriptome comparison suggesting that enthesis cells are more chondrocyte-like than tenocyte-like. Integrative analysis of transcriptome and proteome data identified ten enthesis biomarkers and six tendon biomarkers. The observed gene expression characteristics and differentiation markers shed light into the nature of the cells present at the enthesis. The presented markers will foster enthesis tissue engineering approaches by setting a bench-mark for differentiation of seeded cells towards a physiologically relevant phenotype.
[Mh] Termos MeSH primário: Biomarcadores
Osso e Ossos
Tendões
Engenharia Tecidual
[Mh] Termos MeSH secundário: Animais
Sequenciamento de Nucleotídeos em Larga Escala
Proteoma
Suínos
Transcriptoma
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Biomarkers); 0 (Proteome)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180206
[Lr] Data última revisão:
180206
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180104
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0189668


  9 / 22002 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28460192
[Au] Autor:Karampinos DC; Holwein C; Buchmann S; Baum T; Ruschke S; Gersing AS; Sutter R; Imhoff AB; Rummeny EJ; Jungmann PM
[Ad] Endereço:Department of Radiology, Klinikum rechts der Isar, Technische Universitaet Muenchen, Munich, Germany.
[Ti] Título:Proton Density Fat-Fraction of Rotator Cuff Muscles Is Associated With Isometric Strength 10 Years After Rotator Cuff Repair: A Quantitative Magnetic Resonance Imaging Study of the Shoulder.
[So] Source:Am J Sports Med;45(9):1990-1999, 2017 Jul.
[Is] ISSN:1552-3365
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Quantitative muscle fat-fraction magnetic resonance (MR) imaging techniques correlate with semiquantitative Goutallier scores with failure after rotator cuff (RC) repair. PURPOSE: To investigate the relationship of proton density fat fraction (PDFF) of the RC muscles with semiquantitative MR scores, cartilage T2 relaxation times, and clinical isometric strength measurements in patients 10 years after unilateral RC repair. STUDY DESIGN: Cross-sectional study; Level of evidence, 3. METHODS: Bilateral shoulder MR imaging was performed in 13 patients (11 male, 2 female; age, 72 ± 8 years) 10.9 ± 0.4 years after unilateral autologous periosteal flap augmented RC repair (total shoulders assessed, N = 26). Goutallier classification, muscle atrophy, RC tendon integrity, and cartilage defects were determined based on morphological MR sequences. A paracoronal 2D multi-slice multi-echo sequence was used for quantitative cartilage T2 mapping. A chemical shift-encoding-based water-fat separation technique (based on a 6-echo 3D spoiled gradient echo sequence) was used for quantification of the PDFF of RC muscles. Isometric shoulder abduction strength was measured clinically. Mean and SD, Pearson correlation, and partial Spearman correlation were calculated. RESULTS: There were 6 RC full-thickness retears in ipsilateral shoulders and 6 RC full-thickness tears in contralateral shoulders. Isometric shoulder abduction strength was not significantly different between ipsilateral and contralateral shoulders (50 ± 24 N vs 54 ± 24 N; P = .159). The mean PDFF of RC muscles was 11.7% ± 10.4% (ipsilateral, 14.2% ± 8.5%; contralateral, 9.2% ± 7.8%; P = .002). High supraspinatus PDFF correlated significantly with higher Goutallier scores ( R = 0.75, P < .001) and with lower isometric muscle strength ( R = -0.49, P = .011). This correlation remained significant after adjustment for muscle area measurements and tendon rupture ( R = -0.41, P = .048). More severe cartilage defects at the humerus were significantly associated with higher supraspinatus PDFF ( R = 0.44; P = .023). Cartilage T2 values did not correlate with muscle PDFF ( P > .05). CONCLUSION: MR imaging-derived RC muscle PDFF is associated with isometric strength independent of muscle atrophy and tendon rupture in shoulders with early and advanced degenerative changes. It therefore provides complementary, clinically relevant information in tracking RC muscle composition on a quantitative level.
[Mh] Termos MeSH primário: Cartilagem Articular/diagnóstico por imagem
Imagem por Ressonância Magnética/métodos
Manguito Rotador/diagnóstico por imagem
Articulação do Ombro/diagnóstico por imagem
[Mh] Termos MeSH secundário: Adulto
Artroplastia
Estudos Transversais
Feminino
Seres Humanos
Masculino
Meia-Idade
Força Muscular
Atrofia Muscular/diagnóstico por imagem
Prótons
Manguito Rotador/cirurgia
Lesões do Manguito Rotador/cirurgia
Artropatia de Ruptura do Manguito Rotador/diagnóstico por imagem
Ombro/cirurgia
Articulação do Ombro/cirurgia
Traumatismos dos Tendões/cirurgia
Tendões/cirurgia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Protons)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180205
[Lr] Data última revisão:
180205
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170502
[St] Status:MEDLINE
[do] DOI:10.1177/0363546517703086


  10 / 22002 MEDLINE  
              first record previous record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28465030
[Au] Autor:Bayoglu R; Geeraedts L; Groenen KHJ; Verdonschot N; Koopman B; Homminga J
[Ad] Endereço:Department of Biomechanical Engineering, University of Twente, P.O. Box 217, 7500 AE Enschede, The Netherlands. Electronic address: r.bayoglu@hotmail.com.
[Ti] Título:Twente spine model: A complete and coherent dataset for musculo-skeletal modeling of the thoracic and cervical regions of the human spine.
[So] Source:J Biomech;58:52-63, 2017 06 14.
[Is] ISSN:1873-2380
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Musculo-skeletal modeling could play a key role in advancing our understanding of the healthy and pathological spine, but the credibility of such models are strictly dependent on the accuracy of the anatomical data incorporated. In this study, we present a complete and coherent musculo-skeletal dataset for the thoracic and cervical regions of the human spine, obtained through detailed dissection of an embalmed male cadaver. We divided the muscles into a number of muscle-tendon elements, digitized their attachments at the bones, and measured morphological muscle parameters. In total, 225 muscle elements were measured over 39 muscles. For every muscle element, we provide the coordinates of its attachments, fiber length, tendon length, sarcomere length, optimal fiber length, pennation angle, mass, and physiological cross-sectional area together with the skeletal geometry of the cadaver. Results were consistent with similar anatomical studies. Furthermore, we report new data for several muscles such as rotatores, multifidus, levatores costarum, spinalis, semispinalis, subcostales, transversus thoracis, and intercostales muscles. This dataset complements our previous study where we presented a consistent dataset for the lumbar region of the spine (Bayoglu et al., 2017). Therefore, when used together, these datasets enable a complete and coherent dataset for the entire spine. The complete dataset will be used to develop a musculo-skeletal model for the entire human spine to study clinical and ergonomic applications.
[Mh] Termos MeSH primário: Vértebras Cervicais/anatomia & histologia
Modelos Anatômicos
Músculo Esquelético/anatomia & histologia
Vértebras Torácicas/anatomia & histologia
[Mh] Termos MeSH secundário: Idoso
Seres Humanos
Masculino
Sarcômeros
Tendões/anatomia & histologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1711
[Cu] Atualização por classe:180120
[Lr] Data última revisão:
180120
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170504
[St] Status:MEDLINE



página 1 de 2201 ir para página                         
   


Refinar a pesquisa
  Base de dados : MEDLINE Formulário avançado   

    Pesquisar no campo  
1  
2
3
 
           



Search engine: iAH v2.6 powered by WWWISIS

BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde