Base de dados : MEDLINE
Pesquisa : A03.556.124.526 [Categoria DeCS]
Referências encontradas : 6669 [refinar]
Mostrando: 1 .. 10   no formato [Detalhado]

página 1 de 667 ir para página                         

  1 / 6669 MEDLINE  
              next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:29458958
[Au] Autor:Mangat S; Kozoriz MG; Bicknell S; Spielmann A
[Ad] Endereço:Department of Family Medicine, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
[Ti] Título:The Accuracy of Colorectal Cancer Detection by Computed Tomography in the Unprepared Large Bowel in a Community-Based Hospital.
[So] Source:Can Assoc Radiol J;69(1):92-96, 2018 Feb.
[Is] ISSN:1488-2361
[Cp] País de publicação:Canada
[La] Idioma:eng
[Ab] Resumo:PURPOSE: This retrospective study examined the performance of general radiologists in a community-based hospital in detecting colorectal cancer (CRC) with computed tomography (CT) in the unprepared large bowel. METHODS: The pathology database at a community hospital over the past 7 years (2009-2015) was retrospectively analysed for pathologically proven CRC (924 cases). The provincial hospital information profile for these patients was reviewed to determine if they had an abdominal CT for any reason in the year prior to biopsy. Metrics such as age, sex, time between the CT and biopsy or surgery, whether CRC was initially detected by the radiologist, and if this was an emergency presentation was evaluated. In the cases where CRC was not identified, the CT scans were reanalysed to determine if the CRC was identifiable in retrospect. The sensitivity of detecting CRC by CT scan in the unprepared large bowel was calculated. RESULTS: Of the 924 biopsy proven CRC cases, 22% (207 of 924) of the patients had a CT prior to biopsy. Of these cases, 47% (97 of 207) presented on an emergency basis. Of the cases with imaging in the year prior, about 60% (125 of 207) had cancer prospectively detected by the radiologist. Upon re-examination of the cases in which CRC was not initially detected, 59% were visualized in retrospect. CONCLUSIONS: Community general radiologists can successfully detect CRC with a high degree of accuracy. Reformatted images, bowel wall thickening when regional nodes are prominent, and minimizing oral contrast were helpful in improving detection.
[Mh] Termos MeSH primário: Neoplasias Colorretais/diagnóstico por imagem
Hospitais Comunitários
Tomografia Computadorizada por Raios X/métodos
[Mh] Termos MeSH secundário: Adulto
Idoso
Idoso de 80 Anos ou mais
Feminino
Seres Humanos
Intestino Grosso/diagnóstico por imagem
Masculino
Meia-Idade
Reprodutibilidade dos Testes
Estudos Retrospectivos
Sensibilidade e Especificidade
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180228
[Lr] Data última revisão:
180228
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180221
[St] Status:MEDLINE


  2 / 6669 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Registro de Ensaios Clínicos
Texto completo
[PMID]:28468890
[Au] Autor:Yeung SE; Hilkewich L; Gillis C; Heine JA; Fenton TR
[Ad] Endereço:Nutrition Services and sophia.yeung@ahs.ca.
[Ti] Título:Protein intakes are associated with reduced length of stay: a comparison between Enhanced Recovery After Surgery (ERAS) and conventional care after elective colorectal surgery.
[So] Source:Am J Clin Nutr;106(1):44-51, 2017 Jul.
[Is] ISSN:1938-3207
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Protein can modulate the surgical stress response and postoperative catabolism. Enhanced Recovery After Surgery (ERAS) protocols are evidence-based care bundles that reduce morbidity. In this study, we compared protein adequacy as well as energy intakes, gut function, clinical outcomes, and how well nutritional variables predict length of hospital stay (LOS) in patients receiving ERAS protocols and conventional care. We conducted a prospective cohort study in adult elective colorectal resection patients after conventional ( = 46) and ERAS ( = 69) care. Data collected included preoperative Malnutrition Screening Tool (MST) score, 3-d food records, postoperative nausea, LOS, and complications. Multivariable regression analysis assessed whether low protein intakes and the MST score were predictive of LOS. Total protein intakes were significantly higher in the ERAS group due to the inclusion of oral nutrition supplements (conventional group: 0.33 g · kg · d ; ERAS group: 0.54 g · kg · d ; < 0.02). This group difference in protein intake was maintained in a multivariable model that controlled for differences between baseline and surgical variables ( = 0.001). Oral food intake did not differ between the 2 groups. The ERAS group had shorter LOS ( = 0.049) and fewer total infectious complications ( = 0.01). Nausea was a predictor of protein intake. Nutrition variables were independent predictors of earlier discharge after potential confounders were controlled for. Each unit increase in preoperative MST score predicted longer LOSs of 2.5 d (95% CI: 1.5, 3.5 d; < 0.001), and the consumption of ≥60% of protein requirements during the first 3 d of hospitalization was associated with a shorter LOS of 4.4 d (95% CI: -6.8, -2.0 d; < 0.001). ERAS patients consumed more protein due to the inclusion of oral nutrition supplements. However, total protein intake remained inadequate to meet recommendations. Consumption of ≥60% protein needs after surgery and MST scores were independent predictors of LOS. This trial was registered at clinicaltrials.gov as NCT02940665.
[Mh] Termos MeSH primário: Neoplasias Colorretais/cirurgia
Proteínas na Dieta/administração & dosagem
Suplementos Nutricionais
Procedimentos Cirúrgicos do Sistema Digestório
Tempo de Internação
Estado Nutricional
Cuidados Pós-Operatórios/métodos
[Mh] Termos MeSH secundário: Adulto
Idoso
Cirurgia Colorretal
Procedimentos Cirúrgicos do Sistema Digestório/efeitos adversos
Ingestão de Energia
Comportamento Alimentar
Seres Humanos
Intestino Grosso/cirurgia
Masculino
Meia-Idade
Náusea/etiologia
Necessidades Nutricionais
Assistência Perioperatória
Complicações Pós-Operatórias
Estudos Prospectivos
Padrão de Cuidado
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Dietary Proteins)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:180121
[Lr] Data última revisão:
180121
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170505
[Cl] Clinical Trial:ClinicalTrial
[St] Status:MEDLINE
[do] DOI:10.3945/ajcn.116.148619


  3 / 6669 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28459732
[Au] Autor:Gómez-Izquierdo JC; Trainito A; Mirzakandov D; Stein BL; Liberman S; Charlebois P; Pecorelli N; Feldman LS; Carli F; Baldini G
[Ad] Endereço:From the Department of Anesthesia (J.C.G.-I., A.T., D.M., F.C., G.B.), Department of Surgery (B.L.S., A.S.L., P.C., N.P., L.S.F.), and Steinberg-Bernstein Centre for Minimally Invasive Surgery and Innovation, Department of Surgery (N.P., L.S.F.), McGill University Health Centre, Montreal, Quebec, Canada.
[Ti] Título:Goal-directed Fluid Therapy Does Not Reduce Primary Postoperative Ileus after Elective Laparoscopic Colorectal Surgery: A Randomized Controlled Trial.
[So] Source:Anesthesiology;127(1):36-49, 2017 07.
[Is] ISSN:1528-1175
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Inadequate perioperative fluid therapy impairs gastrointestinal function. Studies primarily evaluating the impact of goal-directed fluid therapy on primary postoperative ileus are missing. The objective of this study was to determine whether goal-directed fluid therapy reduces the incidence of primary postoperative ileus after laparoscopic colorectal surgery within an Enhanced Recovery After Surgery program. METHODS: Randomized patient and assessor-blind controlled trial conducted in adult patients undergoing laparoscopic colorectal surgery within an Enhanced Recovery After Surgery program. Patients were assigned randomly to receive intraoperative goal-directed fluid therapy (goal-directed fluid therapy group) or fluid therapy based on traditional principles (control group). Primary postoperative ileus was the primary outcome. RESULTS: One hundred twenty-eight patients were included and analyzed (goal-directed fluid therapy group: n = 64; control group: n = 64). The incidence of primary postoperative ileus was 22% in the goal-directed fluid therapy and 22% in the control group (relative risk, 1; 95% CI, 0.5 to 1.9; P = 1.00). Intraoperatively, patients in the goal-directed fluid therapy group received less intravenous fluids (mainly less crystalloids) but a greater volume of colloids. The increase of stroke volume and cardiac output was more pronounced and sustained in the goal-directed fluid therapy group. Length of hospital stay, 30-day postoperative morbidity, and mortality were not different. CONCLUSIONS: Intraoperative goal-directed fluid therapy compared with fluid therapy based on traditional principles does not reduce primary postoperative ileus in patients undergoing laparoscopic colorectal surgery in the context of an Enhanced Recovery After Surgery program. Its previously demonstrated benefits might have been offset by advancements in perioperative care.
[Mh] Termos MeSH primário: Procedimentos Cirúrgicos Eletivos
Hidratação/métodos
Íleus/epidemiologia
Intestino Grosso/cirurgia
Laparoscopia
Complicações Pós-Operatórias/epidemiologia
[Mh] Termos MeSH secundário: Canadá/epidemiologia
Feminino
Metas
Seres Humanos
Íleus/prevenção & controle
Masculino
Meia-Idade
Resultado do Tratamento
[Pt] Tipo de publicação:JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1708
[Cu] Atualização por classe:180102
[Lr] Data última revisão:
180102
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170502
[St] Status:MEDLINE
[do] DOI:10.1097/ALN.0000000000001663


  4 / 6669 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28903954
[Au] Autor:Beaumont M; Portune KJ; Steuer N; Lan A; Cerrudo V; Audebert M; Dumont F; Mancano G; Khodorova N; Andriamihaja M; Airinei G; Tomé D; Benamouzig R; Davila AM; Claus SP; Sanz Y; Blachier F
[Ad] Endereço:Mixed research unit Nutrition Physiology and Ingestive Behavior, AgroParisTech, French National Institute for Agricultural Research (INRA), University of Paris-Saclay, Paris, France.
[Ti] Título:Quantity and source of dietary protein influence metabolite production by gut microbiota and rectal mucosa gene expression: a randomized, parallel, double-blind trial in overweight humans.
[So] Source:Am J Clin Nutr;106(4):1005-1019, 2017 Oct.
[Is] ISSN:1938-3207
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Although high-protein diets (HPDs) are frequently consumed for body-weight control, little is known about the consequences for gut microbiota composition and metabolic activity and for large intestine mucosal homeostasis. Moreover, the effects of HPDs according to the source of protein need to be considered in this context. The objective of this study was to evaluate the effects of the quantity and source of dietary protein on microbiota composition, bacterial metabolite production, and consequences for the large intestinal mucosa in humans. A randomized, double-blind, parallel-design trial was conducted in 38 overweight individuals who received a 3-wk isocaloric supplementation with casein, soy protein, or maltodextrin as a control. Fecal and rectal biopsy-associated microbiota composition was analyzed by 16S ribosomal DNA sequencing. Fecal, urinary, and plasma metabolomes were assessed by H-nuclear magnetic resonance. Mucosal transcriptome in rectal biopsies was determined with the use of microarrays. HPDs did not alter the microbiota composition, but induced a shift in bacterial metabolism toward amino acid degradation with different metabolite profiles according to the protein source. Correlation analysis identified new potential bacterial taxa involved in amino acid degradation. Fecal water cytotoxicity was not modified by HPDs, but was associated with a specific microbiota and bacterial metabolite profile. Casein and soy protein HPDs did not induce inflammation, but differentially modified the expression of genes playing key roles in homeostatic processes in rectal mucosa, such as cell cycle or cell death. This human intervention study shows that the quantity and source of dietary proteins act as regulators of gut microbiota metabolite production and host gene expression in the rectal mucosa, raising new questions on the impact of HPDs on the large intestine mucosa homeostasis. This trial was registered at clinicaltrials.gov as NCT02351297.
[Mh] Termos MeSH primário: Bactérias/metabolismo
Dieta com Restrição de Carboidratos
Proteínas na Dieta/farmacologia
Microbioma Gastrointestinal
Mucosa Intestinal/metabolismo
Intestino Grosso/metabolismo
Transcriptoma
[Mh] Termos MeSH secundário: Adulto
Aminoácidos/metabolismo
Bactérias/genética
Caseínas/farmacologia
DNA Bacteriano/análise
Proteínas na Dieta/administração & dosagem
Proteínas na Dieta/metabolismo
Método Duplo-Cego
Fezes
Feminino
Homeostase
Seres Humanos
Mucosa Intestinal/microbiologia
Intestino Grosso/microbiologia
Masculino
Obesidade/dietoterapia
RNA Ribossômico 16S
Reto/metabolismo
Reto/microbiologia
Proteínas de Soja/farmacologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
[Nm] Nome de substância:
0 (Amino Acids); 0 (Caseins); 0 (DNA, Bacterial); 0 (Dietary Proteins); 0 (RNA, Ribosomal, 16S); 0 (Soybean Proteins)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171013
[Lr] Data última revisão:
171013
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170915
[St] Status:MEDLINE
[do] DOI:10.3945/ajcn.117.158816


  5 / 6669 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28865221
[Au] Autor:Dabrowski M; Jakimiuk E; Gajecka M; Gajecki MT; Zielonka L
[Ad] Endereço:.
[Ti] Título:Effect of deoxynivalenol on the levels of toll-like receptors 2 and 9 and their mRNA expression in enterocytes in the porcine large intestine: a preliminary study.
[So] Source:Pol J Vet Sci;20(2):213-220, 2017 Mar 01.
[Is] ISSN:1505-1773
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:Deoxynivalenol (DON), one of the most prevalent mycotoxins in the world, and is capable of inducing immune disorders in humans and animals. The aim of this study was to determine the effect of feed contaminated with DON on the number of TLR2- and TLR9-positive cells and their mRNA expression in the porcine large intestine. The experiment was conducted on two equal groups of pigs (n=4). The experimental group (E) was administered feed contaminated with DON (1008 µg/kg of feed) for 6 weeks, and the control group (C) was administered non-contaminated feed over the same period of time. A decrease in the expression of TLR2 mRNA was noted in the cecum. The percentage of TLR9-positive enterocytes increased in the ascending colon and decreased in the cecum. The results of this study indicate that DON can modify the local immune response by changing the expression of TLRs.
[Mh] Termos MeSH primário: Enterócitos/efeitos dos fármacos
Intestino Grosso/citologia
Suínos
Receptor 2 Toll-Like/metabolismo
Receptor Toll-Like 9/metabolismo
Tricotecenos/toxicidade
[Mh] Termos MeSH secundário: Ração Animal/análise
Ração Animal/toxicidade
Animais
Enterócitos/metabolismo
Contaminação de Alimentos
Regulação da Expressão Gênica/efeitos dos fármacos
RNA Mensageiro/genética
RNA Mensageiro/metabolismo
Receptor 2 Toll-Like/genética
Receptor Toll-Like 9/genética
[Pt] Tipo de publicação:JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
[Nm] Nome de substância:
0 (RNA, Messenger); 0 (Toll-Like Receptor 2); 0 (Toll-Like Receptor 9); 0 (Trichothecenes); JT37HYP23V (deoxynivalenol)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171106
[Lr] Data última revisão:
171106
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170903
[St] Status:MEDLINE


  6 / 6669 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28760826
[Au] Autor:Nakata K; Sugi Y; Narabayashi H; Kobayakawa T; Nakanishi Y; Tsuda M; Hosono A; Kaminogawa S; Hanazawa S; Takahashi K
[Ad] Endereço:From the College of Bioresource Sciences, Nihon University, 1866 Kameino, Fujisawa-shi, Kanagawa 252-0880, Japan.
[Ti] Título:Commensal microbiota-induced microRNA modulates intestinal epithelial permeability through the small GTPase ARF4.
[So] Source:J Biol Chem;292(37):15426-15433, 2017 Sep 15.
[Is] ISSN:1083-351X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The intestinal tract contains many commensal bacteria that modulate various physiological host functions. Dysbiosis of commensal bacteria triggers dysfunction of the intestinal epithelial barrier, leading to the induction or aggravation of intestinal inflammation. To elucidate whether microRNA plays a role in commensal microbiome-dependent intestinal epithelial barrier regulation, we compared transcripts in intestinal epithelial cells (IECs) from conventional and germ-free mice and found that commensal bacteria induced the expression of miR-21-5p in IECs. miR-21-5p increased intestinal epithelial permeability and up-regulated ADP ribosylation factor 4 (ARF4), a small GTPase, in the IEC line Caco-2. We also found that ARF4 expression was up-regulated upon suppression of phosphatase and tensin homolog ( ) and programmed cell death 4 ( ), which are known miR-21-5p targets, by RNAi. Furthermore, ARF4 expression in epithelial cells of the large intestine was higher in conventional mice than in germ-free mice. ARF4 suppression in the IEC line increased the expression of tight junction proteins and decreased intestinal epithelial permeability. These results indicate that commensal microbiome-dependent miR-21-5p expression in IECs regulates intestinal epithelial permeability via ARF4, which may therefore represent a target for preventing or managing dysfunction of the intestinal epithelial barrier.
[Mh] Termos MeSH primário: Fatores de Ribosilação do ADP/metabolismo
Microbioma Gastrointestinal/fisiologia
Mucosa Intestinal/microbiologia
MicroRNAs/metabolismo
Regulação para Cima
[Mh] Termos MeSH secundário: Fatores de Ribosilação do ADP/antagonistas & inibidores
Fatores de Ribosilação do ADP/genética
Animais
Proteínas Reguladoras de Apoptose/antagonistas & inibidores
Proteínas Reguladoras de Apoptose/genética
Proteínas Reguladoras de Apoptose/metabolismo
Células CACO-2
Linhagem Celular Tumoral
Células Cultivadas
Feminino
Vida Livre de Germes
Células HT29
Seres Humanos
Mucosa Intestinal/citologia
Mucosa Intestinal/enzimologia
Mucosa Intestinal/fisiologia
Intestino Grosso/citologia
Intestino Grosso/enzimologia
Intestino Grosso/microbiologia
Intestino Grosso/fisiologia
Camundongos Endogâmicos BALB C
PTEN Fosfo-Hidrolase/antagonistas & inibidores
PTEN Fosfo-Hidrolase/genética
PTEN Fosfo-Hidrolase/metabolismo
Permeabilidade
Proteômica/métodos
Interferência de RNA
Proteínas de Ligação a RNA/antagonistas & inibidores
Proteínas de Ligação a RNA/genética
Proteínas de Ligação a RNA/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Apoptosis Regulatory Proteins); 0 (MIRN-21 microRNA, mouse); 0 (MicroRNAs); 0 (Pdcd4 protein, mouse); 0 (RNA-Binding Proteins); EC 3.1.3.67 (PTEN Phosphohydrolase); EC 3.1.3.67 (Pten protein, mouse); EC 3.6.5.2 (ADP-Ribosylation Factors); EC 3.6.5.2 (ARF4 protein, human); EC 3.6.5.2 (ARF4 protein, mouse)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170927
[Lr] Data última revisão:
170927
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170802
[St] Status:MEDLINE
[do] DOI:10.1074/jbc.M117.788596


  7 / 6669 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28615378
[Au] Autor:van der Wielen N; Moughan PJ; Mensink M
[Ad] Endereço:Division of Human Nutrition, Wageningen University, Wageningen, Netherlands; and.
[Ti] Título:Amino Acid Absorption in the Large Intestine of Humans and Porcine Models.
[So] Source:J Nutr;147(8):1493-1498, 2017 Aug.
[Is] ISSN:1541-6100
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Dietary protein quality has been recognized as a critical issue by international authorities because it can affect important functions of the body. To predict protein quality, the FAO introduced the Digestible Indispensable Amino Acid Score. This score depends on ileal amino acid (AA) digestibility; therefore, the assumption is made that AAs are not absorbed in nutritionally relevant amounts from the large intestine. This article reviews the evidence for this assumption by considering the role of the mammalian large intestine in dietary protein and AA digestion and absorption, with particular reference to adult humans. Although most dietary AAs and peptides are absorbed in the small intestine, substantial amounts can enter the large intestine. Nitrogen is absorbed in the large intestine, and a series of animal experiments indicate a potential small degree of AA absorption. In humans, colonocytes have the capacity for AA absorption because AA transporters are present in the large intestine. The absorption of nutritionally relevant amounts of dietary indispensable AAs and peptides in the human large intestine has not been convincingly demonstrated, however.
[Mh] Termos MeSH primário: Sistemas de Transporte de Aminoácidos/metabolismo
Aminoácidos Essenciais/farmacocinética
Proteínas na Dieta/farmacocinética
Digestão
Absorção Intestinal
Intestino Grosso/metabolismo
[Mh] Termos MeSH secundário: Aminoácidos Essenciais/metabolismo
Animais
Proteínas na Dieta/metabolismo
Proteínas na Dieta/normas
Seres Humanos
Íleo/metabolismo
Nitrogênio/metabolismo
Peptídeos/metabolismo
Suínos
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Amino Acid Transport Systems); 0 (Amino Acids, Essential); 0 (Dietary Proteins); 0 (Peptides); N762921K75 (Nitrogen)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170816
[Lr] Data última revisão:
170816
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170616
[St] Status:MEDLINE
[do] DOI:10.3945/jn.117.248187


  8 / 6669 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
[PMID]:28530216
[Au] Autor:Krzeminski S
[Ad] Endereço:Malopolska District Medical Commission of the Ministry of Internal Affair in Cracow, Poland.
[Ti] Título:[Chilaiditi syndrome - a case report].
[Ti] Título:Zespól Chilaiditi ­ opis przypadku..
[So] Source:Pol Merkur Lekarski;42(250):170-172, 2017 Apr 21.
[Is] ISSN:1426-9686
[Cp] País de publicação:Poland
[La] Idioma:pol
[Ab] Resumo:The abnormality being the result of a certain transposition of the large intestine winding in between diaphragm and the liver, owes it's name to a so called Chilaiditi symptom. This symptom is rarely recognized for at most 0,025-0,28% of the whole population statistics - wise. The Chilaiditi symptom can be examined without any serious (abdominal) pain indication, when conducting the gastrointestinal examination with the implication of the different disorders. When carrying out the diagnostic examination, it is strongly recommended to take notice of patients suffering from the pain in abdominal area, especially in case of the patients with the developed air - structure under the right side copula of the diaphragm. The transposition of the large instestine winding between the diaphragm and the liver, may lead to the blood structure disorders along the part of patient's spot - pressed intestine and be the cause of the other afflictions. The circumstance as such is thus called by the name of Chilaiditi syndrome. The respective recognition of this syndrome may prevent the patient from any unnecessary assignment for a diagnostic and (or) any other therapeutic procedures in place.It may as well minimize the overall diagnostic treatment time lapse - usually concentrated on the pain relief treatment in the aftermath. The patients without examined affliction, (ex.) due to the liver disorders and the awareness of the existence of this syndrome in general, can be an indicator for taking up a decision for when it comes to the liver biopsy. This due to the risk of any perforation of the digestive tract. A CASE REPORT: The report describes case of the 56-year-old male patient, directed onto the surgery department by cause of a quite significant epigastric pain in the right side of the abdomen, however without any of the peritoneal symptoms indicated. The x-ray examination of the chest has indicated presence of the air - structure under the diaphragm copula. Having stated that and without any other signals of the serious abdominal inflammation, this symptom gave trigger for the assumption of the gastrointestinal perforation. As a result, the tomography scan has revealed high curve placement of the diaphragm going along the patient's front lobe of the liver. In the result the Chilaiditi syndrome has been recognized by the patient, where the symptom based treatment has prescribed leading the same to the absolute healing results as an outcome. After leaving the surgery by the patient, it has been made use of the re-directory to the leading gastroenterology practice for any further control checks. In the aftermath of the several year long observation, none of the abdominal pains have been reported back. CONCLUSIONS: Presence of the air - structure under the diaphragm copula without any typical affliction in relation to digestive tract perforation might be the result of transposition of the large intestine winding between diaphragm and the liver - called the Chilaiditi syndrome.
[Mh] Termos MeSH primário: Síndrome de Chilaiditi/patologia
Perfuração Intestinal/complicações
Pneumoperitônio/etiologia
[Mh] Termos MeSH secundário: Dor Abdominal
Seres Humanos
Perfuração Intestinal/diagnóstico por imagem
Perfuração Intestinal/cirurgia
Intestino Grosso/anormalidades
Masculino
Meia-Idade
Pneumoperitônio/diagnóstico por imagem
Pneumoperitônio/cirurgia
Tomografia Computadorizada por Raios X
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170707
[Lr] Data última revisão:
170707
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170523
[St] Status:MEDLINE


  9 / 6669 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
[PMID]:28480860
[Au] Autor:Kairkhanova Y; Chaizhunusоva N; Urazalin M; Stepanenko V; Hоshi M
[Ad] Endereço:Semey State Medical University, Republic of Kazakhstan; A. Tsyb Medical Radiological Research Center - National Medical Research Radiological Center, Ministry of Health of Russian Federation, Obninsk, Russia; Hiroshima University, Hiroshima, Japan.
[Ti] Título:[RESEARCH OF INTESTINAL MICROFLORA IN THE RATS FOLLOWING THE INTERNAL AND EXTERNAL IRRADIATION].
[So] Source:Georgian Med News;(264):103-109, 2017 Mar.
[Is] ISSN:1512-0112
[Cp] País de publicação:Georgia (Republic)
[La] Idioma:rus
[Ab] Resumo:The aim of the research was comparative investigation of the quantitative and qualitative composition of large intestinal microflora following internal (by dispersed powdered 56Mn) and internal exposure of Wistar rats. Ten weeks-old male Wistar rats were used. Rats were divided into four groups: L-56Mn group with 12 rats, H-56Mn with ten rats, 60Co group with nine rats and control group with nine rats. L-56Mn and H-56Mn groups were exposed to two different doses of 56MnO2 powder. 60Co group received 2 Gy of external 60Co γ-ray whole body irradiation. Totally 40 rats. Three rats from each group were sacrificed throw 6 hours and on days 3, 14, and 60 after the exposure. Animals were examined throw 6 hours and on days 3, 14 and 60 after exposure. Although the absorbed doses in large intestine were only 0.69 and 1.90 Gy in 56Mn exposed groups, respectively, changes in large intestinal microflora were evident. After 6 hours and on day 3 after 56Mn exposure amount of main representatives of large intestinal microflora (Bifidobacterium and lactobacilli) was decreased in the dose dependent manner. On the other hand, the amount of conditionally pathogenic bacteria was increased. These changes were persistent even on day 14. External 60Co γ-irradiation at a dose of 2 Gy also changed the intestinal microflora, but these changes were not persistent and on day 14 after irradiation returned to the control level. Our data suggest that internal exposure to dispersed powdered 56Mn has a significant biological impact on the intestinal microflora for a prolonged period of time, when it is compared with the effects of external radiation.
[Mh] Termos MeSH primário: Intestino Grosso/efeitos da radiação
[Mh] Termos MeSH secundário: Animais
Bactérias/isolamento & purificação
Partículas beta
Candida/isolamento & purificação
Radioisótopos de Cobalto
Relação Dose-Resposta à Radiação
Raios gama
Intestino Grosso/microbiologia
Masculino
Manganês
Radioisótopos
Ratos Wistar
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Cobalt Radioisotopes); 0 (Radioisotopes); 42Z2K6ZL8P (Manganese)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170808
[Lr] Data última revisão:
170808
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170509
[St] Status:MEDLINE


  10 / 6669 MEDLINE  
              first record previous record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28425035
[Au] Autor:Junker K; Lutermann H; Mutafchiev Y
[Ad] Endereço:Parasites, Vectors and Vector-Borne Diseases, ARC-Onderstepoort Veterinary Institute, Private Bag X05, Onderstepoort, 0110, South Africa. junkerk@arc.agric.za.
[Ti] Título:A new ascaridid nematode, Mammalakis zambiensis n. sp. (Heterakoidea: Kiwinematidae), from the mole rat Fukomys anselli (Burda, Zima, Scharff, Macholán & Kawalika) (Rodentia: Bathyergidae) in Zambia.
[So] Source:Syst Parasitol;94(5):557-566, 2017 Jun.
[Is] ISSN:1573-5192
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Mammalakis zambiensis n. sp. is described from the large intestine and caecum of Fukomys anselli (Burda, Zima, Scharff, Macholán & Kawalika), a bathyergid rodent endemic to Zambia. Morphological data for comparison with its three congeners, M. macrospiculum (Ortlepp, 1939), M. spalacis (Marcu, 1930) and M. spalaxi (Kozlov & Jangolenko, 1962) are provided. Based on studies of the type-material, observations of hitherto undescribed morphological characters of M. macrospiculum, a parasite of Bathyergus suillus (Schreber) (Hystricomorpha: Bathyergidae) in South Africa, are presented. To date, the generic diagnosis of Mammalakis Inglis, 1991 is based largely on characters of its type-species, M. macrospiculum. In having three rounded lips, not set-off from the body, a stout oesophagus with a flask-shaped posterior bulb, lateral alae that broaden on the level of the precloacal sucker and cloaca, and mature eggs with a smooth shell, M. zambienis n. sp. corresponds to the characters of the genus. However, the presence of lips with anterior flanges that were observed in M. zambiensis n. sp., and also for the first time in M. macrospiculum, are in contrast with the current diagnosis of Mammalakis. Further studies will be needed to determine if an amendment of the generic diagnosis is indicated.
[Mh] Termos MeSH primário: Ratos-Toupeira/parasitologia
Nematoides/classificação
[Mh] Termos MeSH secundário: Animais
Ceco/parasitologia
Intestino Grosso/parasitologia
Nematoides/anatomia & histologia
Especificidade da Espécie
Zâmbia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1706
[Cu] Atualização por classe:171101
[Lr] Data última revisão:
171101
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170421
[St] Status:MEDLINE
[do] DOI:10.1007/s11230-017-9721-9



página 1 de 667 ir para página                         
   


Refinar a pesquisa
  Base de dados : MEDLINE Formulário avançado   

    Pesquisar no campo  
1  
2
3
 
           



Search engine: iAH v2.6 powered by WWWISIS

BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde