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  1 / 13845 MEDLINE  
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[PMID]:29287885
[Au] Autor:Sheehan CC; Lopez J; Elmaraghy CA
[Ad] Endereço:The Ohio State University College of Medicine, Columbus, OH, United States.
[Ti] Título:Low rate of positive bronchoscopy for suspected foreign body aspiration in infants.
[So] Source:Int J Pediatr Otorhinolaryngol;104:72-75, 2018 Jan.
[Is] ISSN:1872-8464
[Cp] País de publicação:Ireland
[La] Idioma:eng
[Ab] Resumo:OBJECTIVES: To describe our institution's low rate of positive bronchoscopy in infants suspected of inhaling a foreign body. STUDY DESIGN: Retrospective chart review. METHODS: A retrospective review was performed of patients at a tertiary children's hospital with suspected inhalation of a foreign body. Charts were reviewed for demographic information, radiologic findings, operative reports, and respiratory viral panels were reviewed. RESULTS: Sixteen pediatric patients under 12 months of age were identified from 2008 to 2016 with a diagnosis of possible airway foreign body inhalation who underwent emergent bronchoscopy. Of these patients, only one was positive for a foreign body present in the airway. The remaining 15 children were found to have a negative direct laryngoscopy and bronchoscopy evaluation for a foreign body. Of these fifteen patients, 14 were found to have structural airway abnormalities and 7 tested positive for a respiratory viral infection. CONCLUSIONS: Our institution has a low rate of positive bronchoscopy for highly suspected foreign body inhalation in a group of patients less than 12 months of age. Patients presenting with respiratory distress, stridor, or other airway symptoms were often found to have an underlying airway abnormality or viral infection, which coupled with an unclear history, would increase the suspicion for an airway foreign body and subsequent decision to perform bronchoscopy. In stable patients, diagnostic evaluation for an underlying respiratory infection should be performed in these cases. LEVEL OF EVIDENCE: Case Series.
[Mh] Termos MeSH primário: Broncoscopia/estatística & dados numéricos
Corpos Estranhos/diagnóstico
Sistema Respiratório/lesões
[Mh] Termos MeSH secundário: Feminino
Corpos Estranhos/epidemiologia
Hospitais Pediátricos
Seres Humanos
Lactente
Recém-Nascido
Laringoscopia/estatística & dados numéricos
Masculino
Estudos Retrospectivos
Centros de Atenção Terciária
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180309
[Lr] Data última revisão:
180309
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171231
[St] Status:MEDLINE


  2 / 13845 MEDLINE  
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[PMID]:28470142
[Au] Autor:Nordlund M; Belka M; Kuczaj AK; Lizal F; Jedelsky J; Elcner J; Jicha M; Sauser Y; Le Bouhellec S; Cosandey S; Majeed S; Vuillaume G; Peitsch MC; Hoeng J
[Ad] Endereço:a Philip Morris International Research & Development, Philip Morris Products S.A. , Neuchâtel , Switzerland.
[Ti] Título:Multicomponent aerosol particle deposition in a realistic cast of the human upper respiratory tract.
[So] Source:Inhal Toxicol;29(3):113-125, 2017 02.
[Is] ISSN:1091-7691
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Inhalation of aerosols generated by electronic cigarettes leads to deposition of multiple chemical compounds in the human airways. In this work, an experimental method to determine regional deposition of multicomponent aerosols in an in vitro segmented, realistic human lung geometry was developed and applied to two aerosols, i.e. a monodisperse glycerol aerosol and a multicomponent aerosol. The method comprised the following steps: (1) lung cast model preparation, (2) aerosol generation and exposure, (3) extraction of deposited mass, (4) chemical quantification and (5) data processing. The method showed good agreement with literature data for the deposition efficiency when using a monodisperse glycerol aerosol, with a mass median aerodynamic diameter (MMAD) of 2.3 µm and a constant flow rate of 15 L/min. The highest deposition surface density rate was observed in the bifurcation segments, indicating inertial impaction deposition. The experimental method was also applied to the deposition of a nebulized multicomponent aerosol with a MMAD of 0.50 µm and a constant flow rate of 15 L/min. The deposited amounts of glycerol, propylene glycol and nicotine were quantified. The three analyzed compounds showed similar deposition patterns and fractions as for the monodisperse glycerol aerosol, indicating that the compounds most likely deposited as parts of the same droplets. The developed method can be used to determine regional deposition for multicomponent aerosols, provided that the compounds are of low volatility. The generated data can be used to validate aerosol deposition simulations and to gain insight in deposition of electronic cigarette aerosols in human airways.
[Mh] Termos MeSH primário: Aerossóis/farmacocinética
Modelos Anatômicos
Sistema Respiratório/metabolismo
[Mh] Termos MeSH secundário: Administração por Inalação
Glicerol/farmacocinética
Seres Humanos
Tamanho da Partícula
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Aerosols); PDC6A3C0OX (Glycerol)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180306
[Lr] Data última revisão:
180306
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170505
[St] Status:MEDLINE
[do] DOI:10.1080/08958378.2017.1315196


  3 / 13845 MEDLINE  
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[PMID]:28448633
[Au] Autor:Scoffield JA; Duan D; Zhu F; Wu H
[Ad] Endereço:Department of Pediatric Dentistry, School of Dentistry, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
[Ti] Título:A commensal streptococcus hijacks a Pseudomonas aeruginosa exopolysaccharide to promote biofilm formation.
[So] Source:PLoS Pathog;13(4):e1006300, 2017 Apr.
[Is] ISSN:1553-7374
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Pseudomonas aeruginosa causes devastating chronic pulmonary infections in cystic fibrosis (CF) patients. Although the CF airway is inhabited by diverse species of microorganisms interlaced within a biofilm, many studies focus on the sole contribution of P. aeruginosa pathogenesis in CF morbidity. More recently, oral commensal streptococci have been identified as cohabitants of the CF lung, but few studies have explored the role these bacteria play within the CF biofilm. We examined the interaction between P. aeruginosa and oral commensal streptococci within a dual species biofilm. Here we report that the CF P. aeruginosa isolate, FRD1, enhances biofilm formation and colonization of Drosophila melanogaster by the oral commensal Streptococcus parasanguinis. Moreover, production of the P. aeruginosa exopolysaccharide, alginate, is required for the promotion of S. parasanguinis biofilm formation and colonization. However, P. aeruginosa is not promoted in the dual species biofilm. Furthermore, we show that the streptococcal adhesin, BapA1, mediates alginate-dependent enhancement of the S. parasanguinis biofilm in vitro, and BapA1 along with another adhesin, Fap1, are required for the in vivo colonization of S. parasanguinis in the presence of FRD1. Taken together, our study highlights a new association between streptococcal adhesins and P. aeruginosa alginate, and reveals a mechanism by which S. parasanguinis potentially colonizes the CF lung and interferes with the pathogenesis of P. aeruginosa.
[Mh] Termos MeSH primário: Biofilmes
Fibrose Cística/microbiologia
Polissacarídeos Bacterianos/metabolismo
Infecções por Pseudomonas/microbiologia
Pseudomonas aeruginosa/fisiologia
[Mh] Termos MeSH secundário: Adesinas Bacterianas/genética
Adesinas Bacterianas/metabolismo
Animais
Drosophila melanogaster
Seres Humanos
Pseudomonas aeruginosa/genética
Pseudomonas aeruginosa/crescimento & desenvolvimento
Pseudomonas aeruginosa/isolamento & purificação
Sistema Respiratório/microbiologia
Simbiose
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Adhesins, Bacterial); 0 (Polysaccharides, Bacterial); 128531-82-8 (exopolysaccharide, Pseudomonas)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:180306
[Lr] Data última revisão:
180306
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170428
[St] Status:MEDLINE
[do] DOI:10.1371/journal.ppat.1006300


  4 / 13845 MEDLINE  
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[PMID]:28450530
[Au] Autor:Hoppe JE; Zemanick ET
[Ad] Endereço:Department of Pediatrics, University of Colorado Denver Anschutz Medical Campus, Aurora, Colorado, USA.
[Ti] Título:Lessons from the lower airway microbiome in early CF.
[So] Source:Thorax;72(12):1063-1064, 2017 12.
[Is] ISSN:1468-3296
[Cp] País de publicação:England
[La] Idioma:eng
[Mh] Termos MeSH primário: Microbiota
Sistema Respiratório
[Mh] Termos MeSH secundário: Fibrose Cística
Regulador de Condutância Transmembrana em Fibrose Cística
Seres Humanos
[Pt] Tipo de publicação:EDITORIAL; COMMENT
[Nm] Nome de substância:
126880-72-6 (Cystic Fibrosis Transmembrane Conductance Regulator)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180222
[Lr] Data última revisão:
180222
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170429
[St] Status:MEDLINE
[do] DOI:10.1136/thoraxjnl-2017-210060


  5 / 13845 MEDLINE  
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[PMID]:29381919
[Au] Autor:Grandjean Lapierre S; Phelippeau M; Hakimi C; Didier Q; Reynaud-Gaubert M; Dubus JC; Drancourt M
[Ad] Endereço:Aix-Marseille Université, URMITE Méditerranée Infection.
[Ti] Título:Cystic fibrosis respiratory tract salt concentration: An Exploratory Cohort Study.
[So] Source:Medicine (Baltimore);96(47):e8423, 2017 Nov.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:In cystic fibrosis patients, electrolytic and osmolality imbalance secondary to cystic fibrosis transmembrane conductance regulator mutations may impact on mucoid secretion accumulation and secondary colonization by opportunistic pathogens such as nontuberculous mycobacteria.We performed a noninvasive exploratory prospective controlled clinical study comparing sputum salinity and acid-base characteristics of cystic fibrosis and noncystic fibrosis control patients. A total of 57 patients and 62 controls were included.Sputum salt concentrations were 10.5 g/L (95% CI: 7.7-13.3) in patients and 7.4 g/L (95% CI: 5.9-8.9) in aged-matched controls, a difference that was found to be statistically significant (P < .05). No difference in pH was observed between patients and controls.These differences in respiratory secretions salt concentrations could influence host-pathogen interactions in the context of cystic fibrosis respiratory infections. We propose to include respiratory secretion salt measurement as a routine analysis on cystic fibrosis patients' sputum submitted for bacterial culture.
[Mh] Termos MeSH primário: Fibrose Cística/patologia
Cloreto de Sódio/análise
Escarro/química
[Mh] Termos MeSH secundário: Adolescente
Adulto
Feminino
Seres Humanos
Concentração de Íons de Hidrogênio
Masculino
Meia-Idade
Estudos Prospectivos
Sistema Respiratório
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
451W47IQ8X (Sodium Chloride)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180220
[Lr] Data última revisão:
180220
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180201
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000008423


  6 / 13845 MEDLINE  
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[PMID]:29226525
[Au] Autor:Cloyd BH
[Ad] Endereço:Department of Anesthesiology, University of Michigan, Ann Arbor, MI, USA.
[Ti] Título:In response to "Interventions designed using quality improvement methods reduce the incidence of serious airway events and airway cardiac arrests during pediatric anesthesia".
[So] Source:Paediatr Anaesth;28(1):73, 2018 01.
[Is] ISSN:1460-9592
[Cp] País de publicação:France
[La] Idioma:eng
[Mh] Termos MeSH primário: Parada Cardíaca/epidemiologia
Melhoria de Qualidade
[Mh] Termos MeSH secundário: Anestesia
Criança
Seres Humanos
Incidência
Sistema Respiratório
[Pt] Tipo de publicação:LETTER; COMMENT
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180105
[Lr] Data última revisão:
180105
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171212
[St] Status:MEDLINE
[do] DOI:10.1111/pan.13287


  7 / 13845 MEDLINE  
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[PMID]:29216202
[Au] Autor:Hang J; Zavaljevski N; Yang Y; Desai V; Ruck RC; Macareo LR; Jarman RG; Reifman J; Kuschner RA; Keiser PB
[Ad] Endereço:Viral Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America.
[Ti] Título:Composition and variation of respiratory microbiota in healthy military personnel.
[So] Source:PLoS One;12(12):e0188461, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Certain occupational and geographical exposures have been associated with an increased risk of lung disease. As a baseline for future studies, we sought to characterize the upper respiratory microbiomes of healthy military personnel in a garrison environment. Nasal, oropharyngeal, and nasopharyngeal swabs were collected from 50 healthy active duty volunteers eight times over the course of one year (1107 swabs, completion rate = 92.25%) and subjected to pyrosequencing of the V1-V3 region of 16S rDNA. Respiratory bacterial taxa were characterized at the genus level, using QIIME 1.8 and the Ribosomal Database Project classifier. High levels of Staphylococcus, Corynebacterium, and Propionibacterium were observed among both nasal and nasopharyngeal microbiota, comprising more than 75% of all operational taxonomical units (OTUs). In contrast, Streptococcus was the sole dominant bacterial genus (approximately 50% of all OTUs) in the oropharynx. The average bacterial diversity was greater in the oropharynx than in the nasal or nasopharyngeal region at all time points. Diversity analysis indicated a significant overlap between nasal and nasopharyngeal samples, whereas oropharyngeal samples formed a cluster distinct from these two regions. The study produced a large set of pyrosequencing data on the V1-V3 region of bacterial 16S rDNA for the respiratory microbiomes of healthy active duty Service Members. Pre-processing of sequencing reads showed good data quality. The derived microbiome profiles were consistent both internally and with previous reports, suggesting their utility for further analyses and association studies based on sequence and demographic data.
[Mh] Termos MeSH primário: Microbiota
Militares
Sistema Respiratório/microbiologia
[Mh] Termos MeSH secundário: Corynebacterium/genética
Corynebacterium/isolamento & purificação
DNA Ribossômico/genética
Feminino
Seres Humanos
Masculino
Cavidade Nasal/microbiologia
Nasofaringe/microbiologia
Propionibacterium/genética
Propionibacterium/isolamento & purificação
RNA Ribossômico 16S/genética
Staphylococcus/genética
Staphylococcus/isolamento & purificação
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (DNA, Ribosomal); 0 (RNA, Ribosomal, 16S)
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171229
[Lr] Data última revisão:
171229
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171208
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0188461


  8 / 13845 MEDLINE  
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[PMID]:29211772
[Au] Autor:Spierenburg EAJ; Smit LAM; Krop EJM; Heederik D; Hylkema MN; Wouters IM
[Ad] Endereço:Institute for Risk Assessment Sciences, Division of Environmental Epidemiology, Utrecht University, Utrecht, the Netherlands.
[Ti] Título:Occupational endotoxin exposure in association with atopic sensitization and respiratory health in adults: Results of a 5-year follow-up.
[So] Source:PLoS One;12(12):e0189097, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The objective of the present longitudinal study was to investigate the effects of occupational endotoxin exposure on respiratory health and atopic sensitization in adults. Health outcomes and personal endotoxin exposure estimates were determined for 234 farmers and agricultural workers both at baseline and 5 years later. A questionnaire was used to assess respiratory symptoms, spirometry tests were performed and total and specific IgE levels were measured in serum. A twofold increase in personal endotoxin exposure was associated with less hay fever (OR 0.68, 95%CI 0.54-0.87) and grass IgE positivity (OR 0.81, 95%CI 0.68-0.97) at both time points ("persistent" versus "never"). Although not statistically significant, a consistent protective pattern was observed for an increased loss of hay fever symptoms (OR 2.19, 95%CI 0.96-4.99) and grass IgE positivity (OR 1.24, 95%CI 0.76-2.02), and for less new-onset of hay fever (OR 0.87, 95%CI 0.65-1.17), grass IgE positivity (OR 0.83, 95%CI 0.61-1.12) and atopic sensitization (OR 0.75, 95%CI 0.55-1.02). Endotoxin exposure was not associated with changes in lung function. We showed that occupational endotoxin exposure is associated with a long-term protective effect on hay fever and grass IgE positivity. Results on longitudinal changes in hay fever, atopy and grass IgE positivity in adulthood were consistent with a protective effect of endotoxin exposure, but results need to be confirmed in larger cohorts. An effect of endotoxin exposure on lung function decline was not found.
[Mh] Termos MeSH primário: Endotoxinas/administração & dosagem
Hipersensibilidade Imediata
Exposição Ocupacional
Sistema Respiratório/efeitos dos fármacos
[Mh] Termos MeSH secundário: Adulto
Estudos de Coortes
Feminino
Seguimentos
Seres Humanos
Imunoglobulina E/sangue
Masculino
Meia-Idade
Testes de Função Respiratória
Sistema Respiratório/fisiopatologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Endotoxins); 37341-29-0 (Immunoglobulin E)
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171229
[Lr] Data última revisão:
171229
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171207
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0189097


  9 / 13845 MEDLINE  
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[PMID]:28741144
[Au] Autor:Makadia LD; Roper PJ; Andrews JO; Tingen MS
[Ad] Endereço:Medical College of Georgia, Augusta University, Augusta, GA, USA.
[Ti] Título:Tobacco Use and Smoke Exposure in Children: New Trends, Harm, and Strategies to Improve Health Outcomes.
[So] Source:Curr Allergy Asthma Rep;17(8):55, 2017 Aug.
[Is] ISSN:1534-6315
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:PURPOSE OF REVIEW: Every day in the USA, approximately 4000 adolescents begin smoking and the adolescent brain is particularly susceptible to nicotine addiction. We present current pediatric trends on tobacco use and exposures, various new products used by adolescents, the adverse biological and behavioral effects of tobacco use and exposures, and tobacco control strategies to eliminate tobacco-related illnesses and deaths in the pediatric population. RECENT FINDINGS: Twelve-20% of women continue to smoke during pregnancy. New research reveals cognitive differences and behavior-control disorders are seen in elementary school children from prenatal and postnatal exposures. Traditional cigarette smoking has decreased in adolescents; novel and appealing tobacco products have captured their attention, particularly electronic cigarettes, and rates double and often triple from middle to high school. Children with asthma and those living in multi-housing units have higher rates of secondhand smoke exposure than non-asthmatics and children living in single-home dwellings. There is no "safe or risk-free" level of tobacco use or exposure. Tobacco use and exposure in childhood and adolescence must be decreased using evidenced-based strategies to improve child health.
[Mh] Termos MeSH primário: Poluição por Fumaça de Tabaco
Uso de Tabaco
[Mh] Termos MeSH secundário: Sistema Cardiovascular/efeitos dos fármacos
Criança
Comportamento Infantil/efeitos dos fármacos
Sistemas Eletrônicos de Liberação de Nicotina
Exposição Ambiental
Feminino
Seres Humanos
Rim/efeitos dos fármacos
Obesidade/epidemiologia
Gravidez
Efeitos Tardios da Exposição Pré-Natal
Sistema Respiratório/efeitos dos fármacos
Instituições Acadêmicas
Fumaça
Produtos do Tabaco/efeitos adversos
Produtos do Tabaco/economia
Produtos do Tabaco/legislação & jurisprudência
Poluição por Fumaça de Tabaco/efeitos adversos
Poluição por Fumaça de Tabaco/legislação & jurisprudência
Poluição por Fumaça de Tabaco/prevenção & controle
Uso de Tabaco/efeitos adversos
Uso de Tabaco/legislação & jurisprudência
Uso de Tabaco/prevenção & controle
Uso de Tabaco/tendências
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Smoke); 0 (Tobacco Smoke Pollution)
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171219
[Lr] Data última revisão:
171219
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170726
[St] Status:MEDLINE
[do] DOI:10.1007/s11882-017-0723-0


  10 / 13845 MEDLINE  
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[PMID]:29173205
[Au] Autor:Guimarães KSL; de Araújo EV; Aquino JS; Gadelha DA; Balarini CM; Costa-Silva JH; Magnani M; Vidal H; Braga VA; de Brito Alves JL
[Ad] Endereço:1Department of Nutrition,Health Sciences Center,Federal University of Paraiba,Joao Pessoa,58051-900,Brazil.
[Ti] Título:Effect of maternal dyslipidaemia on the cardiorespiratory physiology and biochemical parameters in male rat offspring.
[So] Source:Br J Nutr;118(11):930-941, 2017 Dec.
[Is] ISSN:1475-2662
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:The present study evaluated the effects of maternal dyslipidaemia on blood pressure (BP), cardiorespiratory physiology and biochemical parameters in male offspring. Wistar rat dams were fed either a control (CTL) or a dyslipidaemic (DLP) diet during pregnancy and lactation. After weaning, both CTL and DLP offspring received standard diet. On the 30th and 90th day of life, blood samples were collected for metabolic analyses. Direct measurements of BP, respiratory frequency (RF), tidal volume (VT) and ventilation (VE) under baseline condition, as well as during hypercapnia (7 % CO2) and hypoxia (KCN, 0·04 %), were recorded from awake 90-d-old male offspring. DLP dams exhibited raised serum levels of total cholesterol (TC) (4·0-fold), TAG (2·0-fold), VLDL+LDL (7·7-fold) and reduced HDL-cholesterol (2·4-fold), insulin resistance and hepatic steatosis at the end of lactation. At 30 d of age, the DLP offspring showed an increase in the serum levels of TC (P<0·05) and VLDL+LDL (P<0·05) in comparison with CTL offspring. At 90 d of age, DLP offspring exhibited higher mean arterial pressure (MAP, approximately 34 %). In the spectral analysis, the DLP group showed augmented low-frequency (LF) power and LF:high-frequency (HF) ratio when compared with CTL offspring. In addition, the DLP animals showed a larger delta variation in arterial pressure after administration of the ganglionic blocker (P=0·0003). We also found that cardiorespiratory response to hypercapnia and hypoxia was augmented in DLP offspring. In conclusion, the present data show that maternal dyslipidaemia alters cardiorespiratory physiology and may be a predisposing factor for hypertension at adulthood.
[Mh] Termos MeSH primário: Sistema Cardiovascular/fisiopatologia
Dislipidemias/sangue
Fenômenos Fisiológicos da Nutrição Materna
Efeitos Tardios da Exposição Pré-Natal
Sistema Respiratório/fisiopatologia
[Mh] Termos MeSH secundário: Animais
Pressão Sanguínea
Colesterol/sangue
Fígado Gorduroso/fisiopatologia
Feminino
Hipertensão/fisiopatologia
Resistência à Insulina
Masculino
Gravidez
Ratos
Ratos Wistar
Triglicerídeos/sangue
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Triglycerides); 97C5T2UQ7J (Cholesterol)
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171218
[Lr] Data última revisão:
171218
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171128
[St] Status:MEDLINE
[do] DOI:10.1017/S0007114517003014



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