Base de dados : MEDLINE
Pesquisa : A08.800.800.120.030 [Categoria DeCS]
Referências encontradas : 1716 [refinar]
Mostrando: 1 .. 10   no formato [Detalhado]

página 1 de 172 ir para página                         

  1 / 1716 MEDLINE  
              next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28534340
[Au] Autor:Kim JH; Hwang JM
[Ad] Endereço:Department of Radiology, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.
[Ti] Título:Imaging of Cranial Nerves III, IV, VI in Congenital Cranial Dysinnervation Disorders.
[So] Source:Korean J Ophthalmol;31(3):183-193, 2017 Jun.
[Is] ISSN:2092-9382
[Cp] País de publicação:Korea (South)
[La] Idioma:eng
[Ab] Resumo:Congenital cranial dysinnervation disorders are a group of diseases caused by abnormal development of cranial nerve nuclei or their axonal connections, resulting in aberrant innervation of the ocular and facial musculature. Its diagnosis could be facilitated by the development of high resolution thin-section magnetic resonance imaging. The purpose of this review is to describe the method to visualize cranial nerves III, IV, and VI and to present the imaging findings of congenital cranial dysinnervation disorders including congenital oculomotor nerve palsy, congenital trochlear nerve palsy, Duane retraction syndrome, Möbius syndrome, congenital fibrosis of the extraocular muscles, synergistic divergence, and synergistic convergence.
[Mh] Termos MeSH primário: Nervo Abducente/diagnóstico por imagem
Doenças dos Nervos Cranianos/diagnóstico
Síndrome da Retração Ocular/complicações
Imagem por Ressonância Magnética/métodos
Nervo Oculomotor/diagnóstico por imagem
Nervo Troclear/diagnóstico por imagem
[Mh] Termos MeSH secundário: Doenças dos Nervos Cranianos/etiologia
Síndrome da Retração Ocular/diagnóstico
Seres Humanos
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171012
[Lr] Data última revisão:
171012
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170524
[St] Status:MEDLINE
[do] DOI:10.3341/kjo.2017.0024


  2 / 1716 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28526001
[Au] Autor:Kim JH; Hwang JM
[Ad] Endereço:Department of Radiology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.
[Ti] Título:Postoperative full abduction in a patient of Duane retraction syndrome without an abducens nerve: a case report.
[So] Source:BMC Ophthalmol;17(1):75, 2017 May 19.
[Is] ISSN:1471-2415
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Duane retraction syndrome (DRS) consists of abduction deficit, globe retraction and upshoots or downshoots with adduction. The abducens nerve on the affected side is absent in type 1 DRS. After bilateral medial rectus muscle recession in unilateral type 1 DRS may improve the abduction limitation, but still more than -3 limitation remains. CASE PRESENTATION: A 6-month-old boy presented with esotropia which had been noticed in early infancy. He showed limited abduction, fissure narrowing on attempted adduction and a small upshoot OS. Left abducens nerve was not identified on magnetic resonance imaging compatible with Duane retraction syndrome type 1. He showed full abduction after bilateral medial rectus recession of 6.0 mm at the age of 9 months, and remained orthotropia with full abduction OU 2 years postoperatively. He is my only patient with Duane retraction syndrome who showed full abduction after bilateral medial rectus recession. CONCLUSIONS: A patient with the type 1 Duane retraction syndrome rarely may show full abduction after bilateral medial rectus recession mimicking infantile esotropia.
[Mh] Termos MeSH primário: Nervo Abducente/anormalidades
Síndrome da Retração Ocular/cirurgia
Esotropia/cirurgia
Movimentos Oculares/fisiologia
Músculos Oculomotores/cirurgia
Visão Binocular/fisiologia
[Mh] Termos MeSH secundário: Síndrome da Retração Ocular/diagnóstico
Síndrome da Retração Ocular/fisiopatologia
Esotropia/etiologia
Esotropia/fisiopatologia
Seres Humanos
Lactente
Imagem por Ressonância Magnética
Masculino
Músculos Oculomotores/fisiopatologia
Período Pós-Operatório
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170929
[Lr] Data última revisão:
170929
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170521
[St] Status:MEDLINE
[do] DOI:10.1186/s12886-017-0475-6


  3 / 1716 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28345573
[Au] Autor:Gupta C; Sharma P; Saxena R; Garg A; Sharma S
[Ad] Endereço:Department of Ophthalmology, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.
[Ti] Título:Clinical correlation of imaging findings in congenital cranial dysinnervation disorders involving abducens nerve.
[So] Source:Indian J Ophthalmol;65(2):155-159, 2017 Feb.
[Is] ISSN:1998-3689
[Cp] País de publicação:India
[La] Idioma:eng
[Ab] Resumo:PURPOSE: High-resolution magnetic resonance imaging (MRI) of intracranial parts of sixth nerve and seventh nerve and the extraocular muscles (EOMs) in orbit to correlate the clinical characteristics in patients with two special forms of strabismus in congenital cranial dysinnervation disorders which are Duane's retraction syndrome (DRS) and Mobius syndrome. MATERIALS AND METHODS: Morphological analysis by 3T MRI of orbit (using surface coils) and brain (using 32 channel head coil) was performed on 6 patients with clinical DRS (1 bilateral), 2 cases with Mobius syndrome, and 1 case with congenital sixth nerve palsy. These were compared with findings in five controls. RESULTS: We observed absence/hypoplasia of sixth nerve in five out of seven eyes with DRS (71.42%), anomalous course in one eye, sixth and seventh nerve absence/hypoplasia in affected eyes with Mobius syndrome and bilateral absence/hypoplasia of the sixth nerve in congenital sixth nerve palsy. For EOMs we calculated maximum diameter, area, and circumference of muscles using Osirix software, and noticed significant hypoplasia of lateral rectus in comparison to controls (P < 0.001). CONCLUSIONS: MRI gives useful information regarding confirmation of clinical diagnosis and its neurological anomalies in complex cases and helps to plan tailor made surgical management.
[Mh] Termos MeSH primário: Doenças do Nervo Abducente/diagnóstico
Anormalidades Múltiplas
Síndrome da Retração Ocular/diagnóstico
Imagem por Ressonância Magnética/métodos
Síndrome de Möbius/diagnóstico
Músculos Oculomotores/inervação
Órbita/diagnóstico por imagem
[Mh] Termos MeSH secundário: Nervo Abducente/diagnóstico por imagem
Doenças do Nervo Abducente/congênito
Seres Humanos
Imagem Tridimensional
Músculos Oculomotores/diagnóstico por imagem
Projetos Piloto
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170816
[Lr] Data última revisão:
170816
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170328
[St] Status:MEDLINE
[do] DOI:10.4103/ijo.IJO_1013_15


  4 / 1716 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28296553
[Au] Autor:Bolat D; Yildiz D; Bahar S; Yürüker S; Kaymaz F; Ilgin C; Bozkurt EÜ; Karahan S; Sabanci SS
[Ad] Endereço:a Faculty of Veterinary Medicine, Department of Anatomy , Kirikkale University , Kirikkale.
[Ti] Título:A comparative study of oculomotor, trochlear and abducens nerves in Arabian foals.
[So] Source:Biotech Histochem;92(2):149-156, 2017.
[Is] ISSN:1473-7760
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:We investigated the microscopic structure of transverse sections of the oculomotor, trochlear and abducens nerves of Arabian foals using stereological methods. Bilateral nerve pairs from 2-month-old female Arabian foals were analyzed. The tissues were embedded in plastic blocks, then 1 µm thick sections were cut and stained with osmium tetroxide and methylene blue-azure II. Stereology was performed using light microscopy. Morphometry showed that the right and left pairs of nerves were similar. The transverse sectional areas of the oculomotor, trochlear and abducens nerves were 1.93 ± 0.19 mm , 0.32 ± 0.06 mm and 0.70 ± 0.08 mm , respectively. The oculomotor nerve exhibited a significantly greater number of myelinated axons (16755 ± 1279) and trochlear (2656 ± 494) and the abducens nerves (4468 ± 447). The ratio of the axon diameter to myelinated nerve fiber diameter was 0.58, 0.55 and 0.55 for the oculomotor, trochlear and abducens nerves, respectively. Of the three nerves studied, the abducens nerve exhibited the greatest nerve fiber area, myelin area, nerve and axon diameters, and myelin thickness. The ratio of small myelinated nerve fibers was greatest in the oculomotor nerve.
[Mh] Termos MeSH primário: Nervo Abducente/metabolismo
Axônios/metabolismo
Bainha de Mielina/metabolismo
Fibras Nervosas Mielinizadas/metabolismo
Nervo Oculomotor/metabolismo
[Mh] Termos MeSH secundário: Animais
Feminino
Cavalos
Microscopia/métodos
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170330
[Lr] Data última revisão:
170330
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170316
[St] Status:MEDLINE
[do] DOI:10.1080/10520295.2017.1288926


  5 / 1716 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28292832
[Au] Autor:Dietrich H; Glasauer S; Straka H
[Ad] Endereço:Department of Biology II and.
[Ti] Título:Functional Organization of Vestibulo-Ocular Responses in Abducens Motoneurons.
[So] Source:J Neurosci;37(15):4032-4045, 2017 Apr 12.
[Is] ISSN:1529-2401
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Vestibulo-ocular reflexes (VORs) are the dominating contributors to gaze stabilization in all vertebrates. During horizontal head movements, abducens motoneurons form the final element of the reflex arc that integrates visuovestibular inputs into temporally precise motor commands for the lateral rectus eye muscle. Here, we studied a possible differentiation of abducens motoneurons into subtypes by evaluating their morphology, discharge properties, and synaptic pharmacology in semi-intact preparations of larval Extracellular nerve recordings during sinusoidal head motion revealed a continuum of resting rates and activation thresholds during vestibular stimulation. Differences in the sensitivity to changing stimulus frequencies and velocities allowed subdividing abducens motoneurons into two subgroups, one encoding the frequency and velocity of head motion (Group I), and the other precisely encoding angular velocity independent of stimulus frequency (Group II). Computational modeling indicated that Group II motoneurons are the major contributor to actual eye movements over the tested stimulus range. The segregation into two functional subgroups coincides with a differential activation of glutamate receptor subtypes. Vestibular excitatory inputs in Group I motoneurons are mediated predominantly by NMDA receptors and to a lesser extent by AMPA receptors, whereas an AMPA receptor-mediated excitation prevails in Group II motoneurons. Furthermore, glycinergic ipsilateral vestibular inhibitory inputs are activated during the horizontal VOR, whereas the tonic GABAergic inhibition is presumably of extravestibular origin. These findings support the presence of physiologically and pharmacologically distinct functional subgroups of extraocular motoneurons that act in concert to mediate the large dynamic range of extraocular motor commands during gaze stabilization. Outward-directed gaze-stabilizing eye movements are commanded by abducens motoneurons that combine different sensory inputs including signals from the vestibular system about ongoing head movements (vestibulo-ocular reflex). Using an amphibian model, this study investigates whether different types of abducens motoneurons exist that become active during different types of eye movements. The outcome of this study demonstrates the presence of specific motoneuronal populations with pharmacological profiles that match their response dynamics. The evolutionary conservation of the vestibulo-ocular circuitry makes it likely that a similar motoneuronal organization is also implemented in other vertebrates. Accordingly, the physiological and pharmacological understanding of specific motoneuronal contributions to eye movements might help in designing drug therapies for human eye movement dysfunctions such as abducens nerve palsy.
[Mh] Termos MeSH primário: Nervo Abducente/fisiologia
Movimentos Oculares/fisiologia
Movimentos da Cabeça/fisiologia
Neurônios Motores/fisiologia
Reflexo Vestíbulo-Ocular/fisiologia
[Mh] Termos MeSH secundário: Nervo Abducente/anatomia & histologia
Potenciais de Ação/fisiologia
Animais
Feminino
Masculino
Neurônios Motores/citologia
Xenopus laevis
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170419
[Lr] Data última revisão:
170419
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170316
[St] Status:MEDLINE
[do] DOI:10.1523/JNEUROSCI.2626-16.2017


  6 / 1716 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28219790
[Au] Autor:Keifer J; Tiwari NK; Buse L; Zheng Z
[Ad] Endereço:Neuroscience Group, Basic Biomedical Sciences, University of South Dakota, Sanford School of Medicine, Vermillion, SD 57069, United States. Electronic address: jkeifer@usd.edu.
[Ti] Título:Subunit-specific synaptic delivery of AMPA receptors by auxiliary chaperone proteins TARPγ8 and GSG1L in classical conditioning.
[So] Source:Neurosci Lett;645:53-59, 2017 04 03.
[Is] ISSN:1872-7972
[Cp] País de publicação:Ireland
[La] Idioma:eng
[Ab] Resumo:AMPA receptor (AMPAR) trafficking has emerged as a fundamental concept for understanding mechanisms of learning and memory as well as many neurological disorders. Classical conditioning is a simple and highly conserved form of associative learning. Our studies use an ex vivo brainstem preparation in which to study cellular mechanisms underlying learning during a neural correlate of eyeblink conditioning. Two stages of AMPAR synaptic delivery underlie conditioning utilizing sequential trafficking of GluA1-containing AMPARs early in conditioning followed by replacement with GluA4 subunits later. Subunit-selective trafficking of AMPARs is poorly understood. Here, we focused on identification of auxiliary chaperone proteins that traffic AMPARs. The results show that auxiliary proteins TARPγ8 and GSG1L are colocalized with AMPARs on abducens motor neurons that generate the conditioning. Significantly, TARPγ8 was observed to chaperone GluA1-containing AMPARs during synaptic delivery early in conditioning while GSG1L chaperones GluA4 subunits later in conditioning. Interestingly, TARPγ8 remains at the membrane surface as GluA1 subunits are withdrawn and associates with GluA4 when they are delivered to synapses. These data indicate that GluA1- and GluA4-containing AMPARs are selectively chaperoned by TARPγ8 and GSG1L, respectively. Therefore, sequential subunit-selective trafficking of AMPARs during conditioning is achieved through the timing of their interactions with specific auxiliary proteins.
[Mh] Termos MeSH primário: Condicionamento Clássico/fisiologia
Proteínas de Membrana/metabolismo
Chaperonas Moleculares/metabolismo
Receptores de AMPA/metabolismo
Sinapses/metabolismo
Tartarugas/fisiologia
[Mh] Termos MeSH secundário: Nervo Abducente/citologia
Nervo Abducente/fisiologia
Animais
Piscadela
Tronco Encefálico/metabolismo
Membrana Celular/metabolismo
Feminino
Masculino
Neurônios Motores/metabolismo
Subunidades Proteicas/metabolismo
Transporte Proteico
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Membrane Proteins); 0 (Molecular Chaperones); 0 (Protein Subunits); 0 (Receptors, AMPA)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171101
[Lr] Data última revisão:
171101
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170222
[St] Status:MEDLINE


  7 / 1716 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28144774
[Au] Autor:Pizzolorusso F; Cirotti A; Pizzolorusso G
[Ad] Endereço:Research Department, Accademia di Osteopatia e Anatomia (A.O.A.), Via Martiri della Loggia 31, 76123, Andria BT, Italy.
[Ti] Título:Anatomic variation of the abducens nerve in a single cadaver dissection: the "petrobasilar canal".
[So] Source:Acta Neurochir (Wien);159(4):677-680, 2017 Apr.
[Is] ISSN:0942-0940
[Cp] País de publicação:Austria
[La] Idioma:eng
[Ab] Resumo:Anatomic variations of the petrosphenoid ligament, Dorello's canal and the course of the abducens nerve have been extensively described over the past years. In the present report of a single cadaver dissection, we describe an unusual course of the abducens nerve at the level of the petrous bone. The right abducens nerve did not enter Dorello's canal, but ran below the petrous bone through a narrow canal in the petrobasilar suture, which we called the "petrobasilar canal". No anatomic variations of the left abducens nerve were noted.
[Mh] Termos MeSH primário: Nervo Abducente/anatomia & histologia
Variação Anatômica
[Mh] Termos MeSH secundário: Cadáver
Dissecação
Seres Humanos
Masculino
Osso Petroso/anatomia & histologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170927
[Lr] Data última revisão:
170927
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170202
[St] Status:MEDLINE
[do] DOI:10.1007/s00701-017-3096-1


  8 / 1716 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28124175
[Au] Autor:Yang K; Ikawa F; Onishi S; Kolakshyapati M; Takeda M; Yamaguchi S; Ishifuro M; Akiyama Y; Morishige M; Kurisu K
[Ad] Endereço:Department of Neurosurgery, Graduate School of Biomedical and Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8551, Japan.
[Ti] Título:Preoperative simulation of the running course of the abducens nerve in a large petroclival meningioma: a case report and literature review.
[So] Source:Neurosurg Rev;40(2):339-343, 2017 Apr.
[Is] ISSN:1437-2320
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:One of the most important and useful pieces of information in the preoperative evaluation of a large petroclival meningioma is the running course of the abducens nerve. The abducens nerve is small and has a long intracranial course, making it prone to compression by the tumor at various anatomical points. In relatively large tumors, it is difficult to confirm the entire course of the abducens nerve, even by heavy T2-thin slice imaging. We report a case of successful preoperative estimation of the course of the abducens nerve that aided in its complete preservation during the resection of a large petroclival tumor.
[Mh] Termos MeSH primário: Nervo Abducente/diagnóstico por imagem
Neoplasias Encefálicas/diagnóstico por imagem
Fossa Craniana Posterior/diagnóstico por imagem
Meningioma/diagnóstico por imagem
Osso Petroso/diagnóstico por imagem
[Mh] Termos MeSH secundário: Nervo Abducente/cirurgia
Traumatismo do Nervo Abducente/etiologia
Traumatismo do Nervo Abducente/prevenção & controle
Adulto
Neoplasias Encefálicas/cirurgia
Simulação por Computador
Fossa Craniana Posterior/cirurgia
Feminino
Seres Humanos
Imagem por Ressonância Magnética
Meningioma/cirurgia
Procedimentos Neurocirúrgicos/efeitos adversos
Osso Petroso/cirurgia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1706
[Cu] Atualização por classe:171013
[Lr] Data última revisão:
171013
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170127
[St] Status:MEDLINE
[do] DOI:10.1007/s10143-017-0816-1


  9 / 1716 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:26047920
[Au] Autor:Özgür A; Esen K; Kara E; Temel GO
[Ad] Endereço:Faculty of Medicine, Department of Radiology, Mersin University, 34. Cadde, Çiftlikköy Kampüsü, 33343, Mersin, Turkey. anilozgur@yahoo.com.
[Ti] Título:Visualization of the Abducens Nerve in its Petroclival Segment Using Contrast-Enhanced FIESTA MRI: The Size of the Petroclival Venous Confluence Affects Detectability.
[So] Source:Clin Neuroradiol;27(1):97-103, 2017 Mar.
[Is] ISSN:1869-1447
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:PURPOSE: Visualization of the abducens nerve in its petroclival segment still remains challenging. We aimed to investigate the detectability of the petroclival segment of the abducens nerve and to evaluate the role of the size of the petroclival venous confluence (PVC) in the visibility of the nerve using contrast-enhanced fast imaging employing steady-state acquisition (FIESTA) magnetic resonance imaging (MRI). METHODS: We retrospectively evaluated the contrast-enhanced FIESTA images of 237 patients (female/male: 127/110; mean age: 49.0 ± 14.7). Two radiologists divided the imaging findings of the petroclival segments of the abducens nerves into three groups: 0 (not visualized), 1 (partially visualized), and 2 (completely visualized). Another radiologist measured the anteroposterior diameter of the PVC from the clival bony surface to the inner layer of dura at the dural entrance level of the abducens nerve. One-way analysis of variance, Tukey's test, and receiving operating curve analysis were performed. RESULTS: Among 474 abducens nerves, 76 were classified as group 0 (76/474, 16.03 %), 100 were classified as group 1 (100/474, 21.10 %), and 298 were classified as group 2 (298/474, 62.87 %). There was significant difference in mean anteroposterior diameters of the PVC for each group (group 0, 0.95 mm; group 1, 1.80 mm; group 2, 2.51 mm). The cut-off values for the differentiation of group 0 from group 1 and group 1 from group 2 were found to be 1.35 and 2.09 mm, respectively. CONCLUSIONS: Abducens nerve in its petroclival segment can be reliably identified using contrast-enhanced FIESTA MRI especially in those with a greater anteroposterior diameter of the PVC.
[Mh] Termos MeSH primário: Nervo Abducente/anatomia & histologia
Veias Cerebrais/anatomia & histologia
Aumento da Imagem/métodos
Imagem por Ressonância Magnética/métodos
Neuroimagem/métodos
[Mh] Termos MeSH secundário: Adolescente
Adulto
Idoso
Idoso de 80 Anos ou mais
Meios de Contraste
Fossa Craniana Posterior/anatomia & histologia
Fossa Craniana Posterior/irrigação sanguínea
Feminino
Seres Humanos
Masculino
Meia-Idade
Osso Petroso/anatomia & histologia
Reprodutibilidade dos Testes
Sensibilidade e Especificidade
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Contrast Media)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171121
[Lr] Data última revisão:
171121
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150607
[St] Status:MEDLINE
[do] DOI:10.1007/s00062-015-0415-x


  10 / 1716 MEDLINE  
              first record previous record
seleciona
para imprimir
Fotocópia
PubMed Central Texto completo
Texto completo
[PMID]:27352171
[Au] Autor:Yang HK; Kim JH; Hwang JM
[Ad] Endereço:Department of Ophthalmology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.
[Ti] Título:Abducens Nerve in Patients with Type 3 Duane's Retraction Syndrome.
[So] Source:PLoS One;11(6):e0150670, 2016.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: We have previously reported that the presence of the abducens nerve was variable in patients with type 3 Duane's retraction syndrome (DRS), being present in 2 of 5 eyes (40%) and absent in 3 (60%) on magnetic resonance imaging (MRI). The previous study included only 5 eyes with unilateral DRS type 3. OBJECTIVES: To supplement existing scarce pathologic information by evaluating the presence of the abducens nerve using high resolution thin-section MRI system in a larger number of patients with DRS type 3, thus to provide further insight into the pathogenesis of DRS. DATA EXTRACTION: A retrospective review of medical records on ophthalmologic examination and high resolution thin-section MRI at the brainstem level and orbit was performed. A total of 31 patients who showed the typical signs of DRS type 3, including abduction and adduction deficit, globe retraction, narrowing of fissure on adduction and upshoot and/or downshoot, were included. The abducens nerve and any other extraocular muscle abnormalities discovered by MRI were noted. RESULTS: DRS was unilateral in 26 patients (84%) and bilateral in 5 patients (16%). Two out of 5 bilateral patients had DRS type 3 in the right eye and DRS type 1 in the left eye. Of the 34 affected orbits with DRS type 3 in 31 patients, the abducens nerve was absent or hypoplastic in 31 eyes (91%) and present in 3 eyes (9%). Patients with a present abducens nerve showed more limitation in adduction compared to patients with an absent abducens nerve (P = 0.030). CONCLUSIONS: The abducens nerve is absent or hypoplastic in 91% of DRS type 3. Patients with a present abducens nerve showed more prominent limitation of adduction. As DRS type 3 partly share the same pathophysiology with type 1 and 2 DRS, the classification of DRS may have to be revised according to MRI findings.
[Mh] Termos MeSH primário: Nervo Abducente/diagnóstico por imagem
Síndrome da Retração Ocular/diagnóstico por imagem
[Mh] Termos MeSH secundário: Adolescente
Adulto
Idoso
Criança
Pré-Escolar
Feminino
Seres Humanos
Lactente
Imagem por Ressonância Magnética
Masculino
Meia-Idade
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170724
[Lr] Data última revisão:
170724
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160629
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0150670



página 1 de 172 ir para página                         
   


Refinar a pesquisa
  Base de dados : MEDLINE Formulário avançado   

    Pesquisar no campo  
1  
2
3
 
           



Search engine: iAH v2.6 powered by WWWISIS

BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde