Base de dados : MEDLINE
Pesquisa : A08.800.800.120.680.660 [Categoria DeCS]
Referências encontradas : 8873 [refinar]
Mostrando: 1 .. 10   no formato [Detalhado]

página 1 de 888 ir para página                         

  1 / 8873 MEDLINE  
              next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:29186723
[Au] Autor:Cennamo G; Tebaldi S; Amoroso F; Arvanitis D; Breve M; Cennamo G
[Ad] Endereço:Eye Clinic, Department of Public Health, Federico II University, Naples, Italy.
[Ti] Título:Optical Coherence Tomography Angiography in Optic Nerve Drusen.
[So] Source:Ophthalmic Res;59(2):76-80, 2018.
[Is] ISSN:1423-0259
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:AIM: To determine the efficacy of optical coherence tomography angiography (OCT-A) in diagnosing optic nerve head flow impairment in patients with optic nerve drusen. METHODS: Patients affected by optic-nerve head drusen (ONHD) attending the Eye Clinic of the Federico II University of Naples were enrolled in this prospective case series between October 2015 and October 2016. Each patient underwent evaluation of best corrected visual acuity (BCVA), Goldman applanation tonometry, slit-lamp biomicroscopy, fundus examination, standard visual-field testing (perimetry), spectral domain (SD)-OCT and OCT-A. RESULTS: Thirteen patients (6 females and 7 males with a mean age of 22.05 ± 7.54 years) with ONHD (19 eyes) were enrolled. Mean BCVA was 0.16 ± 0.21 LogMar and mean intraocular pressure was 15.68 ± 1.66 mm Hg. The control group constituted 16 individuals (24 eyes). Both ganglion cell complex (GCC) and retinal nerve fiber layer (RNFL) parameters were lower in patients than in controls. Similarly, the flow index (U = 134, p = 0.021) and vessel density (U = 90, p = 0.001) were significantly lower in eyes affected by ONHD than in normal eyes. Visual-field parameters did not differ between the 2 groups. GCC parameters were significantly correlated with OCT-A parameters (p < 0.05). No correlation was found between RNFL and OCT-A parameters. CONCLUSIONS: Our data suggest that OCT-A could be an objective method, helpful in the analysis of flow changes in patients with ONHD.
[Mh] Termos MeSH primário: Drusas do Disco Óptico/patologia
Disco Óptico/patologia
[Mh] Termos MeSH secundário: Adolescente
Adulto
Feminino
Seres Humanos
Pressão Intraocular
Masculino
Fibras Nervosas/patologia
Disco Óptico/diagnóstico por imagem
Drusas do Disco Óptico/diagnóstico por imagem
Drusas do Disco Óptico/fisiopatologia
Estudos Prospectivos
Células Ganglionares da Retina/patologia
Tomografia de Coerência Óptica
Acuidade Visual
Campos Visuais
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180308
[Lr] Data última revisão:
180308
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171130
[St] Status:MEDLINE
[do] DOI:10.1159/000481889


  2 / 8873 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:29298687
[Au] Autor:Aojula A; Mollan SP; Horsburgh J; Yiangou A; Markey KA; Mitchell JL; Scotton WJ; Keane PA; Sinclair AJ
[Ad] Endereço:Institute of Metabolism and Systems Research, University of Birmingham, B15 2TT, Birmingham, UK.
[Ti] Título:Segmentation error in spectral domain optical coherence tomography measures of the retinal nerve fibre layer thickness in idiopathic intracranial hypertension.
[So] Source:BMC Ophthalmol;17(1):257, 2018 Jan 04.
[Is] ISSN:1471-2415
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Optical Coherence Tomography (OCT) imaging is being increasingly used in clinical practice for the monitoring of papilloedema. The aim is to characterise the extent and location of the Retinal Nerve Fibre Layer (RNFL) Thickness automated segmentation error (SegE) by manual refinement, in a cohort of Idiopathic Intracranial Hypertension (IIH) patients with papilloedema and compare this to controls. METHODS: Baseline Spectral Domain OCT (SDOCT) scans from patients with IIH, and controls with no retinal or optic nerve pathology, were examined. The internal limiting membrane and RNFL thickness of the most severely affected eye was examined for SegE and re-segmented. Using ImageJ, the total area of the RNFL thickness was calculated pre and post re-segmentation and the percentage change was determined. The distribution of RNFL thickness error was qualitatively assessed. RESULTS: Significantly greater SegE (p = 0.009) was present in RNFL thickness total area, assessed using ImageJ, in IIH patients (n = 46, 5% ± 0-58%) compared to controls (n = 14, 1% ± 0-6%). This was particularly evident in moderate to severe optic disc swelling (n = 23, 10% ± 0-58%, p < 0.001). RNFL thickness was unable to be quantified using SDOCT in patients with severe papilloedema. CONCLUSIONS: SegE remain a concern for clinicians using SDOCT to monitor papilloedema in IIH, particularly in the assessment of eyes with moderate to severe oedema. Systematic assessment and manual refinement of SegE is therefore important to ensure the accuracy in longitudinal monitoring of patients.
[Mh] Termos MeSH primário: Fibras Nervosas/patologia
Disco Óptico/patologia
Papiledema/diagnóstico
Pseudotumor Cerebral/diagnóstico
Células Ganglionares da Retina/patologia
Tomografia de Coerência Óptica/métodos
Campos Visuais
[Mh] Termos MeSH secundário: Adulto
Feminino
Seres Humanos
Papiledema/etiologia
Papiledema/fisiopatologia
Pseudotumor Cerebral/complicações
Pseudotumor Cerebral/fisiopatologia
Reprodutibilidade dos Testes
Índice de Gravidade de Doença
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180228
[Lr] Data última revisão:
180228
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180105
[St] Status:MEDLINE
[do] DOI:10.1186/s12886-017-0652-7


  3 / 8873 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:29402238
[Au] Autor:Tanyildiz B; Tezcan ME; Kandemir B; Günaydin NT; Göktas E; Tangilntiz A; Arsan AK
[Ad] Endereço:Dr. Lutfi Kirdar Kartal Education and Research Hospital, Department of Ophthalmology, Semsi Denizer Caddesi, E-5, 34890, Kartal Istanbul, Turkey. buraktanyildiz@yahoo.com.
[Ti] Título:Effect of oral Colchicine on Peripapillary retinal nerve fiber layer thickness in patients with familial Mediterranean fever.
[So] Source:BMC Ophthalmol;18(1):27, 2018 Feb 05.
[Is] ISSN:1471-2415
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: The purpose of this study is to investigate whether oral colchicine has an effect on peripapillary retinal nerve fiber layer (pRNFL) thickness of familial Mediterranean fever (FMF) patients. METHODS: We conducted a cross sectional study by comparing pRNFL thickness of FMF patients on colchicine (treated group), newly diagnosed colchicine naïve FMF patients (untreated group) and healthy controls. The study included 66 FMF patients and 32 healthy control subjects. Treated FMF patients were grouped according to colchicine use, duration of use and dosage. pRNFL thickness of the patients and controls were measured by using optical coherence tomography and the measurements were compared. RESULTS: No statistically significant difference was found between the pRNFL thickness in untreated group, treated group and the healthy control group (all p > 0.05). No statistically significant difference was found between pRNFL thickness in the healthy control group and FMF patients grouped according to duration or dosage of colchicine use (all p > 0.05). CONCLUSIONS: According to our study, FMF and oral colchicine use had no statistically significant effect on pRNFL thickness.
[Mh] Termos MeSH primário: Colchicina/uso terapêutico
Febre Familiar do Mediterrâneo/tratamento farmacológico
Fibras Nervosas/efeitos dos fármacos
Células Ganglionares da Retina/efeitos dos fármacos
Moduladores de Tubulina/uso terapêutico
[Mh] Termos MeSH secundário: Administração Oral
Adulto
Estudos Transversais
Feminino
Seres Humanos
Pressão Intraocular
Masculino
Meia-Idade
Fibras Nervosas/patologia
Disco Óptico
Células Ganglionares da Retina/patologia
Tomografia de Coerência Óptica
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Tubulin Modulators); SML2Y3J35T (Colchicine)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180216
[Lr] Data última revisão:
180216
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180207
[St] Status:MEDLINE
[do] DOI:10.1186/s12886-018-0698-1


  4 / 8873 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:29394916
[Au] Autor:Chen Y; Ma X; Hua R
[Ad] Endereço:Department of Ophthalmology, First Hospital of China Medical University, No. 155 Nanjingbei Street, Heping District, Shenyang, Liaoning Province, People's Republic of China.
[Ti] Título:Multi-modality imaging findings of huge intrachoroidal cavitation and myopic peripapillary sinkhole.
[So] Source:BMC Ophthalmol;18(1):24, 2018 Feb 02.
[Is] ISSN:1471-2415
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Peripapillary intrachoroidal cavitation was described as the presence of an asymptomatic, well-circumscribed, yellow-orange, peripapillary lesion at the inferior border of the myopic conus in eyes with high myopia. CASE PRESENTATION: A 66-year-old myopic Chinese man was enrolled and his multi-color imaging examination showed a well-circumscribed, caesious, peripapillary lesion coalesced with the optic nerve head vertically rotated and obliquely tilted, together with an inferotemporal sinkhole in the myopic conus. The optical coherence tomography images showed an intrachoroidal hyporeflective space, schisis, an intracavitary septum located below the retinal pigment epithelium and inserted beneath the optic nerve head, as well as a sinkhole between the peripapillary intrachoroidal cavitation and the vitreous space. CONCLUSIONS: Both myopic colobomas and sinkhole in myopic conus may contribute the coalescence of intrachoroidal cavitation with optic nerve head. These qualitative and quantitative new findings will be beneficial for understanding its pathomorphological mechanism, and the impact on optic nerve tissue of myopic patients.
[Mh] Termos MeSH primário: Doenças da Coroide/diagnóstico por imagem
Anormalidades do Olho/diagnóstico por imagem
Miopia/diagnóstico por imagem
Disco Óptico/anormalidades
Tomografia de Coerência Óptica/métodos
[Mh] Termos MeSH secundário: Idoso
Seres Humanos
Masculino
Imagem Multimodal
Campos Visuais
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180216
[Lr] Data última revisão:
180216
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180204
[St] Status:MEDLINE
[do] DOI:10.1186/s12886-018-0681-x


  5 / 8873 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:29342153
[Au] Autor:Yapp M; Rennie G; Hennessy MP; Kalloniatis M; Zangerl B
[Ad] Endereço:Centre for Eye Health, UNSW Australia, Sydney, New South Wales, Australia.
[Ti] Título:The impact of optic nerve and related characteristics on disc area measurements derived from different imaging techniques.
[So] Source:PLoS One;13(1):e0190273, 2018.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:PURPOSE: Optic nerve head (ONH) assessment and its interpretation in healthy patients and those with glaucoma remains a pivotal topic specifically considering rapid advancements in imaging technologies. We undertook a large-scale, mixed cohort, comparative study to assess the correlation of optic disc measurements between different imaging modalities and investigated the impact of patient and disc associated parameters. METHODS: ONH sizes were obtained from one randomly selected eye of each of 209 patients using stereophotography, confocal scanning laser ophthalmoscopy and two different optical coherence tomographers (OCT). Patient related data, glaucoma status and optic disc variables, specifically oblique insertion, torsion, presence of beta PPA and spherical equivalent were recorded. Measurements between imaging modalities were analysed using Pearson correlation, linear regression analysis and Blend-Altman plots. Individual variables were compared applying multivariate regression analysis, ANOVA and chi square statistics was used to determine correlations between patient and clinical characteristics. RESULTS: Absolute measurements significantly differed between imaging modalities generally producing smaller measurements for OCT derived measurements of Bruch's membrane opening (BMO). Pairwise correlations between imaging modalities were between 0.83 and 0.93 for discs without myopia, oblique insertion, or beta PPA. These features impacted on measurements for individual modalities and consequently contributed to inconsistencies and variability. CONCLUSION: In comparison to planimetry, OCT derived BMO measurements are more variable in the presence of oblique insertion, beta PPA or magnification errors due to myopia. Impact of these factors, however, differs between instruments and needs to be considered to accurately interpret optic disc features in particular within the context of glaucoma diagnosis.
[Mh] Termos MeSH primário: Disco Óptico/diagnóstico por imagem
Nervo Óptico/diagnóstico por imagem
Tomografia de Coerência Óptica/métodos
[Mh] Termos MeSH secundário: Adulto
Análise de Variância
Estudos de Coortes
Feminino
Seres Humanos
Masculino
Meia-Idade
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180215
[Lr] Data última revisão:
180215
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180118
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0190273


  6 / 8873 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:29242987
[Au] Autor:Baneke AJ; Williams KM; Mahroo OA; Mohamed M; Hammond CJ
[Ad] Endereço:Department of Ophthalmology, King's College London, St Thomas' Hospital Campus, Westminster Bridge Road, London, SE1 7EH, UK. alexbaneke@yahoo.co.uk.
[Ti] Título:A twin study of cilioretinal arteries, tilted discs and situs inversus.
[So] Source:Graefes Arch Clin Exp Ophthalmol;256(2):333-340, 2018 Feb.
[Is] ISSN:1435-702X
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:PURPOSE: To establish the prevalence and heritability of cilioretinal arteries (CRAs), tilted discs (TDs) and situs inversus (SI). METHODS: Fundus photos from the Twins UK Adult Twin registry twin database were analyzed: 1812 individuals, 526 complete monozygotic (MZ) twin pairs and 336 complete dizygotic (DZ) pairs. Images were assessed non-stereoscopically on a computer screen by the same ophthalmologist for presence of CRAs, TDs or SI. Prevalence figures, probandwise concordances and heritabilities were calculated. RESULTS: Prevalence of a CRA in subjects' right eyes was 28.6% (26.5-30.8). Prevalence of subjects with a CRA in at least one eye was 45.0% (42.6-47.5), with a TD in at least one eye was 1.2% (0.8-1.9), and with SI at least one eye was 0.5% (0.3-1.0). There was no association between birth weight and presence of CRA. Concordance for CRA in at least one eye (MZ twins) was 60% (95% CI 55-64), and (DZ) was 45% (95% CI 39-51). Heritability for CRAs in at least one eye was 49.4% (95% CI 38.1-59.7) and for both eyes was 32.9% (95% CI 10.4-53.3). We were unable to calculate meaningful heritabilities or concordances for TDs and situs SI, due to insufficient numbers. CONCLUSIONS: The presence of CRAs appears to be moderately heritable, with greater variance explained by individual environmental factors or even stochastic events. They were not associated with low birth weight. Future genetic research and studies of birth/lifecourse cohorts may offer further insights into the etiology of congenital papillovascular abnormalities.
[Mh] Termos MeSH primário: Anormalidades Múltiplas
Artérias Ciliares/patologia
Doenças em Gêmeos/genética
Disco Óptico/anormalidades
Doenças do Nervo Óptico/genética
Artéria Retiniana/patologia
Situs Inversus/genética
[Mh] Termos MeSH secundário: Doenças em Gêmeos/diagnóstico
Feminino
Predisposição Genética para Doença
Seres Humanos
Masculino
Meia-Idade
Doenças do Nervo Óptico/diagnóstico
Sistema de Registros
Situs Inversus/diagnóstico
Gêmeos Monozigóticos
[Pt] Tipo de publicação:JOURNAL ARTICLE; MULTICENTER STUDY; TWIN STUDY
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180214
[Lr] Data última revisão:
180214
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171216
[St] Status:MEDLINE
[do] DOI:10.1007/s00417-017-3859-7


  7 / 8873 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:29238852
[Au] Autor:Maertz J; Kolb JP; Klein T; Mohler KJ; Eibl M; Wieser W; Huber R; Priglinger S; Wolf A
[Ad] Endereço:Augenklinik der Ludwig-Maximilians-Universität München, Campus Innenstadt, Mathildenstraße 8, D-80336, Munich, Germany.
[Ti] Título:Combined in-depth, 3D, en face imaging of the optic disc, optic disc pits and optic disc pit maculopathy using swept-source megahertz OCT at 1050 nm.
[So] Source:Graefes Arch Clin Exp Ophthalmol;256(2):289-298, 2018 Feb.
[Is] ISSN:1435-702X
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:PURPOSE: To demonstrate papillary imaging of eyes with optic disc pits (ODP) or optic disc pit associated maculopathy (ODP-M) with ultrahigh-speed swept-source optical coherence tomography (SS-OCT) at 1.68 million A-scans/s. To generate 3D-renderings of the papillary area with 3D volume-reconstructions of the ODP and highly resolved en face images from a single densely-sampled megahertz-OCT (MHz-OCT) dataset for investigation of ODP-characteristics. METHODS: A 1.68 MHz-prototype SS-MHz-OCT system at 1050 nm based on a Fourier-domain mode-locked laser was employed to acquire high-definition, 3D datasets with a dense sampling of 1600 × 1600 A-scans over a 45° field of view. Six eyes with ODPs, and two further eyes with glaucomatous alteration or without ocular pathology are presented. 3D-rendering of the deep papillary structures, virtual 3D-reconstructions of the ODPs and depth resolved isotropic en face images were generated using semiautomatic segmentation. RESULTS: 3D-rendering and en face imaging of the optic disc, ODPs and ODP associated pathologies showed a broad spectrum regarding ODP characteristics. Between individuals the shape of the ODP and the appending pathologies varied considerably. MHz-OCT en face imaging generates distinct top-view images of ODPs and ODP-M. MHz-OCT generates high resolution images of retinal pathologies associated with ODP-M and allows visualizing ODPs with depths of up to 2.7 mm. CONCLUSIONS: Different patterns of ODPs can be visualized in patients for the first time using 3D-reconstructions and co-registered high-definition en face images extracted from a single densely sampled 1050 nm megahertz-OCT (MHz-OCT) dataset. As the immediate vicinity to the SAS and the site of intrapapillary proliferation is located at the bottom of the ODP it is crucial to image the complete structure and the whole depth of ODPs. Especially in very deep pits, where non-swept-source OCT fails to reach the bottom, conventional swept-source devices and the MHz-OCT alike are feasible and beneficial methods to examine deep details of optic disc pathologies, while the MHz-OCT bears the advantage of an essentially swifter imaging process.
[Mh] Termos MeSH primário: Anormalidades do Olho/diagnóstico
Imagem Tridimensional
Macula Lutea/patologia
Disco Óptico/patologia
Doenças Retinianas/diagnóstico
Tomografia de Coerência Óptica/instrumentação
[Mh] Termos MeSH secundário: Adolescente
Adulto
Idoso
Desenho de Equipamento
Feminino
Seres Humanos
Masculino
Meia-Idade
Disco Óptico/anormalidades
Projetos Piloto
Reprodutibilidade dos Testes
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180214
[Lr] Data última revisão:
180214
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171215
[St] Status:MEDLINE
[do] DOI:10.1007/s00417-017-3857-9


  8 / 8873 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28457789
[Au] Autor:Cameron JR; Megaw RD; Tatham AJ; McGrory S; MacGillivray TJ; Doubal FN; Wardlaw JM; Trucco E; Chandran S; Dhillon B
[Ad] Endereço:Anne Rowling Regenerative Neurology Clinic, University of Edinburgh, Chancellor's Building, 49 Little France Crescent, Edinburgh, EH16 4SB, UK; Centre for Clinical Brain Sciences, University of Edinburgh, Chancellor's Building, 49 Little France Crescent, Edinburgh, EH16 4SB, UK. Electronic address:
[Ti] Título:Lateral thinking - Interocular symmetry and asymmetry in neurovascular patterning, in health and disease.
[So] Source:Prog Retin Eye Res;59:131-157, 2017 Jul.
[Is] ISSN:1873-1635
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:No biological system or structure is likely to be perfectly symmetrical, or have identical right and left forms. This review explores the evidence for eye and visual pathway asymmetry, in health and in disease, and attempts to provide guidance for those studying the structure and function of the visual system, where recognition of symmetry or asymmetry may be essential. The principal question with regards to asymmetry is not 'are the eyes the same?', for some degree of asymmetry is pervasive, but 'when are they importantly different?'. Knowing if right and left eyes are 'importantly different' could have significant consequences for deciding whether right or left eyes are included in an analysis or for examining the association between a phenotype and ocular parameter. The presence of significant asymmetry would also have important implications for the design of normative databases of retinal and optic nerve metrics. In this review, we highlight not only the universal presence of asymmetry, but provide evidence that some elements of the visual system are inherently more asymmetric than others, pointing to the need for improved normative data to explain sources of asymmetry and their impact on determining associations with genetic, environmental or health-related factors and ultimately in clinical practice.
[Mh] Termos MeSH primário: Fibras Nervosas/patologia
Disco Óptico/patologia
Nervo Óptico/patologia
Doenças Retinianas/diagnóstico
Células Ganglionares da Retina/patologia
Vasos Retinianos/patologia
Tomografia de Coerência Óptica/métodos
[Mh] Termos MeSH secundário: Seres Humanos
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180202
[Lr] Data última revisão:
180202
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170502
[St] Status:MEDLINE


  9 / 8873 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28452838
[Au] Autor:Cheng YC; Shen JH; Chao AN; Chen KJ
[Ad] Endereço:Department of Ophthalmology, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Tayouan, Taiwan.
[Ti] Título:Later Development of Posterior Staphyloma in Choroidal Osteoma With Choroidal Neovascularization.
[So] Source:Retina;37(8):e95-e96, 2017 Aug.
[Is] ISSN:1539-2864
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Coristoma/complicações
Neoplasias da Coroide/complicações
Neovascularização de Coroide/complicações
Disco Óptico/patologia
Doenças do Nervo Óptico/etiologia
Osteoma/complicações
[Mh] Termos MeSH secundário: Coristoma/diagnóstico
Corioide/patologia
Neoplasias da Coroide/diagnóstico
Neovascularização de Coroide/diagnóstico
Diagnóstico Diferencial
Angiofluoresceinografia
Seguimentos
Fundo de Olho
Seres Humanos
Masculino
Meia-Idade
Doenças do Nervo Óptico/diagnóstico
Osteoma/diagnóstico
Tomografia de Coerência Óptica
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180202
[Lr] Data última revisão:
180202
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170429
[St] Status:MEDLINE
[do] DOI:10.1097/IAE.0000000000001683


  10 / 8873 MEDLINE  
              first record previous record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28460051
[Au] Autor:Malmqvist L; Lindberg AW; Dahl VA; Jørgensen TM; Hamann S
[Ad] Endereço:Department of Ophthalmology, Rigshospitalet, University of Copenhagen, Glostrup, Denmark.
[Ti] Título:Quantitatively Measured Anatomic Location and Volume of Optic Disc Drusen: An Enhanced Depth Imaging Optical Coherence Tomography Study.
[So] Source:Invest Ophthalmol Vis Sci;58(5):2491-2497, 2017 05 01.
[Is] ISSN:1552-5783
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Purpose: Optic disc drusen (ODD) are found in up to 2.4% of the population and are known to cause visual field defects. The purpose of the current study was to investigate how quantitatively estimated volume and anatomic location of ODD influence optic nerve function. Methods: Anatomic location, volume of ODD, and peripapillary retinal nerve fiber layer and macular ganglion cell layer thickness were assessed in 37 ODD patients using enhanced depth imaging optical coherence tomography. Volume of ODD was calculated by manual segmentation of ODD in 97 B-scans per eye. Anatomic characteristics were compared with optic nerve function using automated perimetric mean deviation (MD) and multifocal visual evoked potentials. Results: Increased age (P = 0.015); larger ODD volume (P = 0.002); and more superficial anatomic ODD location (P = 0.007) were found in patients with ODD visible by ophthalmoscopy compared to patients with buried ODD. In a multivariate analysis, a worsening of MD was significantly associated with larger ODD volume (P < 0.0001). No association was found between MD and weighted anatomic location, age, and visibility by ophthalmoscopy. Decreased ganglion cell layer thickness was significantly associated with worse MD (P = 0.025) and had a higher effect on MD when compared to retinal nerve fiber layer thickness. Conclusions: Large ODD volume is associated with optic nerve dysfunction. The worse visual field defects associated with visible ODD should only be ascribed to larger ODD volume and not to a more superficial anatomic ODD location.
[Mh] Termos MeSH primário: Drusas do Disco Óptico/diagnóstico
Disco Óptico/patologia
Tomografia de Coerência Óptica/métodos
Campos Visuais
[Mh] Termos MeSH secundário: Adulto
Potenciais Evocados Visuais
Feminino
Seres Humanos
Masculino
Fibras Nervosas/patologia
Oftalmoscopia
Drusas do Disco Óptico/fisiopatologia
Estudos Prospectivos
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; OBSERVATIONAL STUDY; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1707
[Cu] Atualização por classe:180124
[Lr] Data última revisão:
180124
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170502
[St] Status:MEDLINE
[do] DOI:10.1167/iovs.17-21608



página 1 de 888 ir para página                         
   


Refinar a pesquisa
  Base de dados : MEDLINE Formulário avançado   

    Pesquisar no campo  
1  
2
3
 
           



Search engine: iAH v2.6 powered by WWWISIS

BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde