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Pesquisa : A08.800.800.120.910.120 [Categoria DeCS]
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[PMID]:28847113
[Au] Autor:Zhang Y; Yu X
[Ad] Endereço:Department of Neurosurgery, PLA General Hospital, Beijing, China.
[Ti] Título:In Reply to "Predicting Shape, Location, and Course of Facial Nerve in Relation to Large Vestibular Schwannoma on Diffusion Tensor Imaging with Intraoperative Correlation: Important Surgical Adjunct".
[So] Source:World Neurosurg;105:1003, 2017 09.
[Is] ISSN:1878-8769
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Nervo Facial
Neuroma Acústico/cirurgia
[Mh] Termos MeSH secundário: Nervo Coclear
Imagem de Tensor de Difusão
Seres Humanos
[Pt] Tipo de publicação:LETTER; COMMENT
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170914
[Lr] Data última revisão:
170914
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170830
[St] Status:MEDLINE


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[PMID]:28847112
[Au] Autor:Satyarthee GD
[Ad] Endereço:Department of Neurosurgery, Neurosciences Center, AIIMS New Delhi, New Delhi, India. Electronic address: drguruduttaaiims@gmail.com.
[Ti] Título:Predicting Shape, Location, and Course of Facial Nerve in Relation to Large Vestibular Schwannoma on Diffusion Tensor Imaging with Intraoperative Correlation: Important Surgical Adjunct.
[So] Source:World Neurosurg;105:1002, 2017 09.
[Is] ISSN:1878-8769
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Nervo Facial
Neuroma Acústico/cirurgia
[Mh] Termos MeSH secundário: Nervo Coclear
Imagem de Tensor de Difusão
Seres Humanos
[Pt] Tipo de publicação:LETTER; COMMENT
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170914
[Lr] Data última revisão:
170914
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170830
[St] Status:MEDLINE


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[PMID]:28695768
[Au] Autor:Bojrab D; Zhang B; Jiang H; Zhang L; Cohen DS; Luo X; Hu Z
[Ad] Endereço:1 Department of Otolaryngology-Head and Neck Surgery, Wayne State University, Detroit, Michigan, USA.
[Ti] Título:Expression of Oligodendrocyte Marker during Peripheral-Central Transitional Zone Formation of the Postnatal Mouse Cochlear Nerve.
[So] Source:Otolaryngol Head Neck Surg;157(3):488-492, 2017 Sep.
[Is] ISSN:1097-6817
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Objective To better understand oligodendrocyte protein expression along the mouse cochlear nerve in postnatal mice. Study Design In vivo murine study. Setting Research laboratory. Subjects and Methods Swiss Webster mice used at multiple postnatal days (0, 1, 3, 5, 7, 8, 10, 14, 30, and 60). There were 5 replicates at each postnatal day. Cryosection was done to produce sections that included the cochlear nucleus, cochlear nerve, and cochlea in a single sample. Differential interference contrast (DIC) microscopy and immunofluorescence with antibodies specific to the oligodendrocyte protein Olig2 were used to study the cochlear nerve of Swiss Webster mice at postnatal days. Results The myelination of central nervous system projections initiates in close proximity to the peripheral nervous system-central nervous system transitional zone (PCTZ), and oligodendrocytes in neonatal mice are seen with immunohistochemistry peripheral to the DIC-PCTZ interface. Conclusions As the PCTZ migrates from the brain to the cochlea, oligodendrocytes are a part of peripheral extension of central nervous system tissue along the cochlear nerve. Expression of oligodendrocyte marker Oligo2 was observed peripherally to the formation of PCTZ, as determined by DIC microscopy.
[Mh] Termos MeSH primário: Claudinas/biossíntese
Nervo Coclear/crescimento & desenvolvimento
Oligodendroglia/metabolismo
[Mh] Termos MeSH secundário: Animais
Animais Recém-Nascidos
Biomarcadores/análise
Claudinas/análise
Camundongos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Biomarkers); 0 (Claudins); 0 (Cldn11 protein, mouse)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170929
[Lr] Data última revisão:
170929
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170712
[St] Status:MEDLINE
[do] DOI:10.1177/0194599817718806


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[PMID]:28675079
[Au] Autor:Peng KA; Kuan EC; Hagan S; Wilkinson EP; Miller ME
[Ad] Endereço:1 House Clinic, Los Angeles, California, USA.
[Ti] Título:Cochlear Nerve Aplasia and Hypoplasia: Predictors of Cochlear Implant Success.
[So] Source:Otolaryngol Head Neck Surg;157(3):392-400, 2017 Sep.
[Is] ISSN:1097-6817
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Objective To identify factors predicting performance outcomes following cochlear implantation in patients with cochlear nerve aplasia or hypoplasia. Data Sources Individual patient data extracted from published case series and reports. Review Methods The MEDLINE database, Cochrane Library, Embase, Web of Science, and Google Scholar were queried for "cochlear implant" in conjunction with "aplasia" or "hypoplasia" between 1985 and 2015. Eighteen studies were included describing 97 subjects with individual postimplant auditory data. Postimplant performance was categorized as follows: level 1, nonstimulation/minimal detection; level 2, improved detection; level 3, closed-set speech perception; or level 4, open-set speech perception. The subjects achieving speech perception (levels 3 and 4) were descriptively compared with those who did not. Results Subjects with a hypoplastic cochlear nerve on magnetic resonance imaging had higher reported rates of achieving speech perception than those with an aplastic nerve. Subjects with syndromic medical comorbidities had higher reported rates of nonstimulation than nonsyndromic subjects. The data showed that some children with an aplastic cochlear nerve or those with partial electrode insertion could obtain levels of speech discrimination. Reporting of patient characteristics and auditory outcomes was extremely variable across studies. Conclusion As previously shown, cochlear implant in patients with cochlear nerve aplasia or hypoplasia can provide meaningful hearing for select patients. The current study suggests that presence of a cochlear nerve on magnetic resonance imaging and lack of comorbid medical syndrome are associated with better auditory outcomes in such patients. Future efforts to report individual data in a consistent manner may allow better determination of predictive factors.
[Mh] Termos MeSH primário: Implante Coclear
Nervo Coclear/anormalidades
Nervo Coclear/cirurgia
[Mh] Termos MeSH secundário: Seres Humanos
Prognóstico
Indução de Remissão
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170929
[Lr] Data última revisão:
170929
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170705
[St] Status:MEDLINE
[do] DOI:10.1177/0194599817718798


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[PMID]:28672008
[Au] Autor:Hackelberg S; Tuck SJ; He L; Rastogi A; White C; Liu L; Prieskorn DM; Miller RJ; Chan C; Loomis BR; Corey JM; Miller JM; Duncan RK
[Ad] Endereço:Kresge Hearing Research Institute, Department of Otolaryngology-Head & Neck Surgery, University of Michigan, Ann Arbor, MI, United States of America.
[Ti] Título:Nanofibrous scaffolds for the guidance of stem cell-derived neurons for auditory nerve regeneration.
[So] Source:PLoS One;12(7):e0180427, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Impairment of spiral ganglion neurons (SGNs) of the auditory nerve is a major cause for hearing loss occurring independently or in addition to sensory hair cell damage. Unfortunately, mammalian SGNs lack the potential for autonomous regeneration. Stem cell based therapy is a promising approach for auditory nerve regeneration, but proper integration of exogenous cells into the auditory circuit remains a fundamental challenge. Here, we present novel nanofibrous scaffolds designed to guide the integration of human stem cell-derived neurons in the internal auditory meatus (IAM), the foramen allowing passage of the spiral ganglion to the auditory brainstem. Human embryonic stem cells (hESC) were differentiated into neural precursor cells (NPCs) and seeded onto aligned nanofiber mats. The NPCs terminally differentiated into glutamatergic neurons with high efficiency, and neurite projections aligned with nanofibers in vitro. Scaffolds were assembled by seeding GFP-labeled NPCs on nanofibers integrated in a polymer sheath. Biocompatibility and functionality of the NPC-seeded scaffolds were evaluated in vivo in deafened guinea pigs (Cavia porcellus). To this end, we established an ouabain-based deafening procedure that depleted an average 72% of SGNs from apex to base of the cochleae and caused profound hearing loss. Further, we developed a surgical procedure to implant seeded scaffolds directly into the guinea pig IAM. No evidence of an inflammatory response was observed, but post-surgery tissue repair appeared to be facilitated by infiltrating Schwann cells. While NPC survival was found to be poor, both subjects implanted with NPC-seeded and cell-free control scaffolds showed partial recovery of electrically-evoked auditory brainstem thresholds. Thus, while future studies must address cell survival, nanofibrous scaffolds pose a promising strategy for auditory nerve regeneration.
[Mh] Termos MeSH primário: Nervo Coclear/fisiologia
Células-Tronco Embrionárias/citologia
Nanofibras
Regeneração Nervosa/fisiologia
Neurônios/citologia
Engenharia Tecidual
[Mh] Termos MeSH secundário: Animais
Materiais Biocompatíveis
Tronco Encefálico/fisiologia
Diferenciação Celular
Transplante de Células
Surdez/terapia
Feminino
Proteínas de Fluorescência Verde/genética
Cobaias
Seres Humanos
Masculino
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Biocompatible Materials); 147336-22-9 (Green Fluorescent Proteins)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171006
[Lr] Data última revisão:
171006
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170704
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0180427


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[PMID]:28566097
[Au] Autor:Tahir E; Bajin MD; Atay G; Mocan BÖ; Sennaroglu L
[Ad] Endereço:Department of Otolaryngology - Head and Neck Surgery,Hacettepe University,Ankara,Turkey.
[Ti] Título:Bony cochlear nerve canal and internal auditory canal measures predict cochlear nerve status.
[So] Source:J Laryngol Otol;131(8):676-683, 2017 Aug.
[Is] ISSN:1748-5460
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:OBJECTIVES: The bony cochlear nerve canal is the space between the fundus of the internal auditory canal and the base of the cochlear modiolus that carries cochlear nerve fibres. This study aimed to determine the distribution of bony labyrinth anomalies and cochlear nerve anomalies in patients with bony cochlear nerve canal and internal auditory canal atresia and stenosis, and then to compare the diameter of the bony cochlear nerve canal and internal auditory canal with cochlear nerve status. METHODS: The study included 38 sensorineural hearing loss patients (59 ears) in whom the bony cochlear nerve canal diameter at the mid-modiolus was 1.5 mm or less. Atretic and stenotic bony cochlear nerve canals were examined separately, and internal auditory canals with a mid-point diameter of less than 2 mm were considered stenotic. Temporal bone computed tomography and magnetic resonance imaging scans were reviewed to determine cochlear nerve status. RESULTS: Cochlear hypoplasia was noted in 44 out of 59 ears (75 per cent) with a bony cochlear nerve canal diameter at the mid-modiolus of 1.5 mm or less. Approximately 33 per cent of ears with bony cochlear nerve canal stenosis also had a stenotic internal auditory canal and 84 per cent had a hypoplastic or aplastic cochlear nerve. All patients with bony cochlear nerve canal atresia had cochlear nerve deficiency. The cochlear nerve was hypoplastic or aplastic when the diameter of the bony cochlear nerve canal was less than 1.5 mm and the diameter of the internal auditory canal was less than 2 mm. CONCLUSION: The cochlear nerve may be aplastic or hypoplastic even if temporal bone computed tomography findings indicate a normal cochlea. If possible, patients scheduled to receive a cochlear implant should undergo both computed tomography and magnetic resonance imaging of the temporal bone. The bony cochlear nerve canal and internal auditory canal are complementary structures, and both should be assessed to determine cochlear nerve status.
[Mh] Termos MeSH primário: Cóclea/anormalidades
Nervo Coclear/patologia
Meato Acústico Externo/patologia
Perda Auditiva Neurossensorial/patologia
[Mh] Termos MeSH secundário: Adolescente
Estudos de Casos e Controles
Criança
Pré-Escolar
Cóclea/diagnóstico por imagem
Nervo Coclear/anormalidades
Nervo Coclear/diagnóstico por imagem
Constrição Patológica/diagnóstico por imagem
Constrição Patológica/patologia
Meato Acústico Externo/diagnóstico por imagem
Feminino
Perda Auditiva Neurossensorial/diagnóstico por imagem
Seres Humanos
Lactente
Imagem por Ressonância Magnética/métodos
Masculino
Osso Temporal/diagnóstico por imagem
Tomografia Computadorizada por Raios X/métodos
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170831
[Lr] Data última revisão:
170831
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170602
[St] Status:MEDLINE
[do] DOI:10.1017/S0022215117001141


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[PMID]:28483247
[Au] Autor:Goyal S; Krishnan SS; Kameswaran M; Vasudevan MC; Ranjith; Natarajan K
[Ad] Endereço:Department of ENT, Command Hospital (Southern Command), Wanowrie, Pune 411040, Maharashtra, India. Electronic address: drsunilgoyal@yahoo.co.in.
[Ti] Título:Does cerebellar flocculus size affect subjective outcomes in pediatric auditory brainstem implantation.
[So] Source:Int J Pediatr Otorhinolaryngol;97:30-34, 2017 Jun.
[Is] ISSN:1872-8464
[Cp] País de publicação:Ireland
[La] Idioma:eng
[Ab] Resumo:OBJECTIVES: The objectives of study was to 1) Describe relevant surgical anatomy in defining and accessing the lateral recess for placement of electrode, 2) Propose a working classification for grades of Flocculus; 3) To determine if different grades of cerebellar flocculus effects placement of ABI electrode and subjective outcomes in implantees. METHODS: Our study was a prospective study, and comprised of cohort of 12 patients who underwent ABI surgery via retrosigmoid approach between 1 Jan 2012 to 31 Dec 2014. All children with congenital profound sensorineural hearing loss with either absent cochlea or cochlear nerve were included in the study. Relevant anatomy was noted. We also noted down the difficulty encountered during the placement of ABI electrode. Auditory perception and speech intelligibility was scored post operatively for 1 year. RESULTS: Cerebellar flocculus was divided into 4 grades depending on the morphology of cerebellar flocculus. It was noted that Grade 3 & 4 flocculus (Group B) had difficult ABI electrode placement in comparison to Grade 1 & 2 flocculus (Group A). The subjective outcomes of Group A was better than Group B. However the p value was not statistically significant. CONCLUSION: Cerebellar flocculus can be graded depending on morphology and size. Flocculus of higher grades can make the placement of ABI electrodes difficult and adversely effects the postoperative subjective outcomes.
[Mh] Termos MeSH primário: Implante Auditivo de Tronco Encefálico/métodos
Percepção Auditiva/fisiologia
Cerebelo/fisiologia
Inteligibilidade da Fala/fisiologia
Percepção da Fala/fisiologia
[Mh] Termos MeSH secundário: Adolescente
Implantes Auditivos de Tronco Encefálico
Criança
Pré-Escolar
Nervo Coclear/anormalidades
Feminino
Seres Humanos
Masculino
Estudos Prospectivos
Resultado do Tratamento
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170907
[Lr] Data última revisão:
170907
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170510
[St] Status:MEDLINE


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[PMID]:28368665
[Au] Autor:Naguib NNN; Hey C; Shaaban MS; Elabd AM; Hassan HHM; Gruber-Rouh T; Kaltenbach B; Harth M; Ackermann H; Stöver T; Vogl TJ; Nour-Eldin NA
[Ad] Endereço:1 Institute for Diagnostic and Interventional Radiology, Frankfurt University Hospital, Frankfurt, Germany.
[Ti] Título:Assessment of the cochlear nerve to facial nerve size ratio using MR multiplanar reconstruction of the internal auditory canal in patients presenting with acquired long-standing hearing loss.
[So] Source:Br J Radiol;90(1073):20160870, 2017 May.
[Is] ISSN:1748-880X
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: To test using the facial nerve as a reference for assessment of the cochlear nerve size in patients with acquired long-standing sensorineural hearing loss (SNHL) using MRI multiplanar reconstruction. METHODS: The study was retrospectively performed on 86 patients. Group 1 (study group, n = 53) with bilateral long-standing SNHL. Group 2 (control group, n = 33) without hearing loss. The nerve size was measured by drawing a region of interest around the cross-sectional circumference of the nerve in multiplanar reconstruction images. RESULTS: No significant correlation was noted between the cochlear nerve and facial nerve size, and the patient's age, gender and weight (p > 0.05). In Group 1, the mean ratio of the cochlear to facial nerve size was 0.99 ± 0.30 (range: 0.52-1.86) and 1.12 ± 0.35 (range: 0.34-2.3) for the right and left sides, respectively. In Group 2, it was 1.18 ± 0.23 (range: 0.78-1.71) and 1.25 ± 0.25 (range: 0.85-1.94) for the right and left sides, respectively. The cochlear nerve size was statistically (p = 0.0004) smaller in Group 1 than in Group 2. CONCLUSION: The cochlear nerve size and the cochlear to facial nerve size ratio are significantly smaller in patients with acquired long-standing SNHL. Advances in knowledge: The facial nerve can be used as a reference for assessment of the cochlear nerve in patients with acquired long-standing SNHL.
[Mh] Termos MeSH primário: Nervo Coclear/diagnóstico por imagem
Orelha Interna/diagnóstico por imagem
Nervo Facial/diagnóstico por imagem
Perda Auditiva Neurossensorial/diagnóstico por imagem
Imagem por Ressonância Magnética
Osso Temporal/diagnóstico por imagem
[Mh] Termos MeSH secundário: Adolescente
Adulto
Idoso
Idoso de 80 Anos ou mais
Feminino
Seres Humanos
Processamento de Imagem Assistida por Computador
Imagem por Ressonância Magnética/métodos
Masculino
Meia-Idade
Estudos Retrospectivos
Fatores de Tempo
Adulto Jovem
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170922
[Lr] Data última revisão:
170922
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170404
[St] Status:MEDLINE
[do] DOI:10.1259/bjr.20160870


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[PMID]:28121970
[Au] Autor:Colletti G; Mandalà M; Colletti V; Deganello A; Allevi F; Colletti L
[Ad] Endereço:*Department of Maxillo-Facial Surgery, University of Milan †Otological and Skull Base Surgery Department, Azienda Ospedaliera Universitaria Senese, Siena ‡ENT Department, University of Verona, Verona §University of Firenze, Florence ||International Center for Performing and Teaching Auditory Brainstem Surgery in Children, Milan, Italy.
[Ti] Título:Resorbable Mesh Cranioplasty Repair of Bilateral Cerebrospinal Fluid Leaks Following Pediatric Simultaneous Bilateral Auditory Brainstem Implant Surgery.
[So] Source:Otol Neurotol;38(4):606-609, 2017 Apr.
[Is] ISSN:1537-4505
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: To present a child with cochlear nerve deficiency (CND) who received simultaneous bilateral simultaneous auditory brainstem implants (BS-ABI) and subsequently presented with bilateral cerebrospinal fluid (CSF) leaks unresponsive to standard treatments. To propose a novel rigid retrosigmoid cranioplasty for treating and preventing CSF leaks in children at high risk for this complication. PATIENT: A 3.5-year-old child with CND, vertebral defects, anal atresia, cardiac defects, tracheo-esophageal fistula, renal anomalies, and limb abnormalities, coloboma, heart defect, atresia choanae, retarded growth and development, genital abnormality, and ear abnormality, Arnold Chiari malformation, previous treated tracheo-esophageal fistula underwent BS-ABI. Postoperatively, the child had recurrent bilateral retroauricular fluid collections. A standard revision procedure revealed breaches in the dural closure, migration of the auditory brainstem implantation (ABI) receiver stimulator on both sides and was unsuccessful in stopping the leak. INTERVENTIONS: Bilateral repair with free fat grafting filling the craniectomy space and two absorbable meshes of poly-L-D-lactic (PLDL) acid stabilized with PLDL pins on the surrounding cranium, one to stabilize the fat graft and one to fix the ABI receiver stimulators inside the subperiosteal pockets. MAIN OUTCOME MEASURE: CSF leak recurrence, postoperative computed tomographic (CT) scans, intra- and postoperative simultaneous electrically evoked auditory brainstem responses (EABRs). Subjective and objective assessment of ABI function. RESULTS: No postoperative CSF leaks at 60 days follow-up. EABRs and consistent behavioral responses obtained at initial mapping on both sides. CONCLUSIONS: The use of BS-ABI likely contributed to bilateral CSF leaks requiring revision surgeries in this child. Simultaneous bilateral craniotomies can put patients at risk for CSF leak. A novel cranioplasty technique employed finally proved successful in stopping the CSF leak in this case.
[Mh] Termos MeSH primário: Implante Auditivo de Tronco Encefálico/efeitos adversos
Vazamento de Líquido Cefalorraquidiano/cirurgia
Nervo Coclear/anormalidades
Craniotomia/métodos
Complicações Pós-Operatórias/cirurgia
[Mh] Termos MeSH secundário: Implantes Auditivos de Tronco Encefálico/efeitos adversos
Vazamento de Líquido Cefalorraquidiano/etiologia
Pré-Escolar
Craniotomia/instrumentação
Otopatias/etiologia
Otopatias/cirurgia
Feminino
Seres Humanos
Masculino
Complicações Pós-Operatórias/etiologia
Reoperação/métodos
Resultado do Tratamento
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170908
[Lr] Data última revisão:
170908
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170126
[St] Status:MEDLINE
[do] DOI:10.1097/MAO.0000000000001338


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[PMID]:28109502
[Au] Autor:Rudic M; Wong W; Viner S; Strachan D; Raine C
[Ad] Endereço:Yorkshire Auditory Implant Service (YAIS), Bradford Royal Infirmary, Listening for Life Centre, Bradford Teaching Hospitals NHS Foundation Trust, UK. Electronic address: Milan.Rudic@bthft.nhs.uk.
[Ti] Título:Bilateral cochlear nerve absence in a 3 year old child with VACTERL association.
[So] Source:Int J Pediatr Otorhinolaryngol;93:71-74, 2017 Feb.
[Is] ISSN:1872-8464
[Cp] País de publicação:Ireland
[La] Idioma:eng
[Ab] Resumo:We report a case of a 3 year old boy with bilateral profound sensorineural hearing loss diagnosed from New Born Hearing Screening, with severe form of VACTERL association. He was referred to our Cochlear Implant Unit for assessment with regard to the possibility of cochlear implantation. MRI findings have showed bilateral vestibulocochlear cystic abnormalities. Only single nerve noted within the IAM on the right and likely single nerve within the IAM on the left. Hence, decision was made not to offer cochlear implantation. This is the first report of severe bilateral cochleovestibular nerve abnormalities to be associated with VACTERL.
[Mh] Termos MeSH primário: Anormalidades Múltiplas/diagnóstico
Canal Anal/anormalidades
Nervo Coclear/anormalidades
Esôfago/anormalidades
Perda Auditiva Neurossensorial/congênito
Cardiopatias Congênitas/diagnóstico
Rim/anormalidades
Deformidades Congênitas dos Membros/diagnóstico
Coluna Vertebral/anormalidades
Traqueia/anormalidades
[Mh] Termos MeSH secundário: Pré-Escolar
Nervo Coclear/diagnóstico por imagem
Perda Auditiva Neurossensorial/diagnóstico
Seres Humanos
Imagem por Ressonância Magnética
Masculino
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170123
[St] Status:MEDLINE



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