Base de dados : MEDLINE
Pesquisa : A11.284 [Categoria DeCS]
Referências encontradas : 398 [refinar]
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[PMID]:28796234
[Au] Autor:Martell JD; Deerinck TJ; Lam SS; Ellisman MH; Ting AY
[Ad] Endereço:Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.
[Ti] Título:Electron microscopy using the genetically encoded APEX2 tag in cultured mammalian cells.
[So] Source:Nat Protoc;12(9):1792-1816, 2017 Sep.
[Is] ISSN:1750-2799
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Electron microscopy (EM) is the premiere technique for high-resolution imaging of cellular ultrastructure. Unambiguous identification of specific proteins or cellular compartments in electron micrographs, however, remains challenging because of difficulties in delivering electron-dense contrast agents to specific subcellular targets within intact cells. We recently reported enhanced ascorbate peroxidase 2 (APEX2) as a broadly applicable genetic tag that generates EM contrast on a specific protein or subcellular compartment of interest. This protocol provides guidelines for designing and validating APEX2 fusion constructs, along with detailed instructions for cell culture, transfection, fixation, heavy-metal staining, embedding in resin, and EM imaging. Although this protocol focuses on EM in cultured mammalian cells, APEX2 is applicable to many cell types and contexts, including intact tissues and organisms, and is useful for numerous applications beyond EM, including live-cell proteomic mapping. This protocol, which describes procedures for sample preparation from cell monolayers and cell pellets, can be completed in 10 d, including time for APEX2 fusion construct validation, cell growth, and solidification of embedding resins. Notably, the only additional steps required relative to a standard EM sample preparation are cell transfection and a 2- to 45-min staining period with 3,3-diaminobenzidine (DAB) and hydrogen peroxide (H O ).
[Mh] Termos MeSH primário: Ascorbato Peroxidases/genética
Técnicas Citológicas/métodos
Técnicas Genéticas
Microscopia Eletrônica/métodos
Imagem Molecular/métodos
[Mh] Termos MeSH secundário: Animais
Células COS
Células Cultivadas
Estruturas Celulares/ultraestrutura
Cercopithecus aethiops
Células HEK293
Hipocampo/citologia
Seres Humanos
Ratos
Proteínas Recombinantes de Fusão/genética
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Recombinant Fusion Proteins); EC 1.11.1.11 (Ascorbate Peroxidases)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170821
[Lr] Data última revisão:
170821
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170811
[St] Status:MEDLINE
[do] DOI:10.1038/nprot.2017.065


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[PMID]:28671662
[Au] Autor:Takakura H; Zhang Y; Erdmann RS; Thompson AD; Lin Y; McNellis B; Rivera-Molina F; Uno SN; Kamiya M; Urano Y; Rothman JE; Bewersdorf J; Schepartz A; Toomre D
[Ad] Endereço:Department of Cell Biology, Yale University School of Medicine, New Haven, Connecticut, USA.
[Ti] Título:Long time-lapse nanoscopy with spontaneously blinking membrane probes.
[So] Source:Nat Biotechnol;35(8):773-780, 2017 Aug.
[Is] ISSN:1546-1696
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Imaging cellular structures and organelles in living cells by long time-lapse super-resolution microscopy is challenging, as it requires dense labeling, bright and highly photostable dyes, and non-toxic conditions. We introduce a set of high-density, environment-sensitive (HIDE) membrane probes, based on the membrane-permeable silicon-rhodamine dye HMSiR, that assemble in situ and enable long time-lapse, live-cell nanoscopy of discrete cellular structures and organelles with high spatiotemporal resolution. HIDE-enabled nanoscopy movies span tens of minutes, whereas movies obtained with labeled proteins span tens of seconds. Our data reveal 2D dynamics of the mitochondria, plasma membrane and filopodia, and the 2D and 3D dynamics of the endoplasmic reticulum, in living cells. HIDE probes also facilitate acquisition of live-cell, two-color, super-resolution images, expanding the utility of nanoscopy to visualize dynamic processes and structures in living cells.
[Mh] Termos MeSH primário: Estruturas Celulares/ultraestrutura
Corantes Fluorescentes/análise
Corantes Fluorescentes/química
Microscopia de Fluorescência/métodos
Nanotecnologia/métodos
[Mh] Termos MeSH secundário: Células HeLa
Seres Humanos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Fluorescent Dyes)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170927
[Lr] Data última revisão:
170927
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170704
[St] Status:MEDLINE
[do] DOI:10.1038/nbt.3876


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[PMID]:27650960
[Au] Autor:Fabbri J; Maggiore MA; Pensel PE; Denegri GM; Gende LB; Elissondo MC
[Ad] Endereço:Laboratorio de Zoonosis Parasitarias, Departamento de Biología, Facultad de Ciencias Exactas y Naturales, Universidad Nacional de Mar del Plata (UNMdP), Funes 3350, 7600, Mar del Plata, Argentina; Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Argentina.
[Ti] Título:In vitro and in vivo efficacy of carvacrol against Echinococcus granulosus.
[So] Source:Acta Trop;164:272-279, 2016 Dec.
[Is] ISSN:1873-6254
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Currently, benzimidazoles are used as chemotherapeutic agents and as a complement to surgery and PAIR in the treatment of cystic echinococcosis (CE). They are generally applied at high doses causing side effects and, 50% of cases do not respond favorably to such chemotherapy. The use of essential oils obtained by distillation from aromatic plants would be an effective alternative or complementary to the synthetic compounds, because would not bring the appearance of side effects. Carvacrol and his isomer thymol are the main phenolic components from essential oils of Origanum vulgare (oregano) and Thymus vulgaris (thyme). The aim of the present work was to evaluate the in vitro and in vivo efficacy of carvacrol against Echinococcus granulosus metacestodes. For the in vitro assay, protoscoleces and cysts of E. granulosus were incubated with carvacrol at the following final concentrations: 10, 5 and 1µg/ml of carvacrol. The maximum protoscolicidal effect was found with 10µg/ml of carvacrol. Results of viability tests were consistent with the structural and ultrastructural damage observed in protoscoleces. Ultrastructural studies revealed that the germinal layer of cysts treated with carvacrol lost the multicellular structure feature. In the clinical efficacy study, a reduction in cyst weight was observed after the administration of 40mg/kg of carvacrol during 20days in mice with cysts developed during 4 months, compared to that of those collected from control mice. Given that the in vivo effect of carvacrol was comparable with the treatment of reference with ABZ and the fact that is a safe compound, we postulated that carvacrol may be an alternative option for treatment of human CE.
[Mh] Termos MeSH primário: Equinococose/tratamento farmacológico
Echinococcus granulosus/efeitos dos fármacos
Monoterpenos/farmacologia
Óleos Voláteis/farmacologia
[Mh] Termos MeSH secundário: Animais
Estruturas Celulares/efeitos dos fármacos
Cistos/tratamento farmacológico
Cistos/parasitologia
Equinococose/parasitologia
Camundongos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Monoterpenes); 0 (Oils, Volatile); 9B1J4V995Q (carvacrol)
[Em] Mês de entrada:1701
[Cu] Atualização por classe:170718
[Lr] Data última revisão:
170718
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160922
[St] Status:MEDLINE


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[PMID]:27203462
[Au] Autor:Qiao J; Mu X; Qi L
[Ad] Endereço:Beijing National Laboratory for Molecular Sciences; Key Laboratory of Analytical Chemistry for Living Biosystems, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China; University of Chinese Academy of Sciences, 100049 Beijing, China.
[Ti] Título:Construction of fluorescent polymeric nano-thermometers for intracellular temperature imaging: A review.
[So] Source:Biosens Bioelectron;85:403-413, 2016 Nov 15.
[Is] ISSN:1873-4235
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Multitudinous biochemical reactions occur in living cells, creating and releasing free energy to impel numerous cellular activities. Surplus energy is expelled as heat and resulted in elevated temperature, which induce control of gene expression, tumour metabolism and etc. Sensitive measurement of temperature on nanoscale in cells with ideal fluorescent probes is a great challenge in many areas. By taking the advantages of polymers in tunable critical solution temperature range and good biocompatibility, fluorescent polymeric thermometers (FPT) have drawn extensive attention because they are capable of accurate monitoring temperature with high spatial resolution at cellular level. This review offers a general overview of recent examples of FPT working in cells. The strategy for design and synthesis of the FPT has been highlighted. Furthermore, the applications of the constructed FPT for intracellular temperature variations under normal and external stimuli conditions have been discussed. Deep understanding of these aspects would lead to improvement in designing of unique FPT with real function and applications for intracellular temperature sensing. It will pave a new way not only for the study of intrinsic relationship between temperature and organelle function, but also provide the possibility for deep understanding of intracellular biological processes.
[Mh] Termos MeSH primário: Corantes Fluorescentes/química
Nanoestruturas/química
Imagem Óptica/métodos
Polímeros/química
Termômetros
Termometria/métodos
[Mh] Termos MeSH secundário: Animais
Estruturas Celulares/química
Corantes Fluorescentes/análise
Seres Humanos
Nanoestruturas/análise
Nanotecnologia/métodos
Imagem Óptica/instrumentação
Polimerização
Polímeros/análise
Temperatura Ambiente
Termometria/instrumentação
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Fluorescent Dyes); 0 (Polymers)
[Em] Mês de entrada:1701
[Cu] Atualização por classe:170809
[Lr] Data última revisão:
170809
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160521
[St] Status:MEDLINE


  5 / 398 MEDLINE  
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[PMID]:26863993
[Au] Autor:Lavrov AI; Kosevich IA
[Ad] Endereço:Department of Invertebrate Zoology, Faculty of Biology, Lomonosov Moscow State University, Moscow, Russia.
[Ti] Título:Sponge cell reaggregation: Cellular structure and morphogenetic potencies of multicellular aggregates.
[So] Source:J Exp Zool A Ecol Genet Physiol;325(2):158-77, 2016 Feb.
[Is] ISSN:1932-5231
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Sponges (phylum Porifera) are one of the most ancient extant multicellular animals and can provide valuable insights into origin and early evolution of Metazoa. High plasticity of cell differentiations and anatomical structure is characteristic feature of sponges. Present study deals with sponge cell reaggregation after dissociation as the most outstanding case of sponge plasticity. Dynamic of cell reaggregation and structure of multicellular aggregates of three demosponge species (Halichondria panicea (Pallas, 1766), Haliclona aquaeductus (Sсhmidt, 1862), and Halisarca dujardinii Johnston, 1842) were studied. Sponge tissue dissociation was performed mechanically. Resulting cell suspensions were cultured at 8-10°C for at least 5 days. Structure of multicellular aggregates was studied by light, transmission and scanning electron microscopy. Studied species share common stages of cell reaggregation-primary multicellular aggregates, early-stage primmorphs and primmorphs, but the rate of reaggregation varies considerably among species. Only cells of H. dujardinii are able to reconstruct functional and viable sponge after primmorphs formation. Sponge reconstruction in this species occurs due to active cell locomotion. Development of H. aquaeductus and H. panicea cells ceases at the stages of early primmorphs and primmorphs, respectively. Development of aggregates of these species is most likely arrested due to immobility of the majority of cells inside them. However, the inability of certain sponge species to reconstruct functional and viable individuals during cell reaggregation may be not a permanent species-specific characteristic, but depends on various factors, including the stage of the life cycle and experimental conditions.
[Mh] Termos MeSH primário: Morfogênese
Poríferos/citologia
Poríferos/crescimento & desenvolvimento
[Mh] Termos MeSH secundário: Animais
Agregação Celular
Movimento Celular
Estruturas Celulares/citologia
Microscopia Eletrônica de Varredura
Microscopia Eletrônica de Transmissão
Poríferos/ultraestrutura
Especificidade da Espécie
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1702
[Cu] Atualização por classe:170207
[Lr] Data última revisão:
170207
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160212
[St] Status:MEDLINE
[do] DOI:10.1002/jez.2006


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[PMID]:26678758
[Au] Autor:Paswan MB; Chudasama MM; Mitra M; Bhayani K; George B; Chatterjee S; Mishra S
[Ad] Endereço:Institute of Forensic Science, Gujarat Forensic Sciences University, DFS Campus, Gandhinagar, Gujarat, India.
[Ti] Título:Fluorescence Quenching Property of C-Phycocyanin from Spirulina platensis and its Binding Efficacy with Viable Cell Components.
[So] Source:J Fluoresc;26(2):577-83, 2016 Mar.
[Is] ISSN:1573-4994
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Phycocyanin is a natural brilliant blue colored, fluorescent protein, which is commonly present in cyanobacteria. In this study, C-phycocyanin was extracted and purified from Spirulina platensis, which are multicellular and filamentous cyanobacteria of greater importance because of its various biological and pharmacological potential. It was analyzed for its binding affinity towards blood cells, algal cells, genomic DNA of microalgae, and bacteria at different temperature and incubation time. It showed good binding affinity with these components even at low concentration of 2.5 µM. The purpose of this study was to evaluate the applicability of C-phycocyanin as a green fluorescent dye substituting carcinogenic chemical dyes.
[Mh] Termos MeSH primário: Estruturas Celulares/metabolismo
Ficocianina/química
Ficocianina/metabolismo
Spirulina/metabolismo
[Mh] Termos MeSH secundário: Animais
Plaquetas/metabolismo
Bovinos
DNA Bacteriano/metabolismo
Eritrócitos/metabolismo
Escherichia coli/metabolismo
Fluorescência
Genoma Bacteriano
Linfócitos/metabolismo
Microalgas/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (DNA, Bacterial); 11016-15-2 (Phycocyanin)
[Em] Mês de entrada:1612
[Cu] Atualização por classe:171027
[Lr] Data última revisão:
171027
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:151219
[St] Status:MEDLINE
[do] DOI:10.1007/s10895-015-1742-7


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[PMID]:26673020
[Au] Autor:Rohne P; Prochnow H; Koch-Brandt C
[Ti] Título:The CLU-files: disentanglement of a mystery.
[So] Source:Biomol Concepts;7(1):1-15, 2016 Feb.
[Is] ISSN:1868-503X
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:The multifaceted protein clusterin (CLU) has been challenging researchers for more than 35 years. The characterization of CLU as a molecular chaperone was one of the major breakthroughs in CLU research. Today, secretory clusterin (sCLU), also known as apolipoprotein J (apoJ), is considered one of the most important extracellular chaperones ever found. It is involved in a broad range of physiological and pathophysiological functions, where it exerts a cytoprotective role. Descriptions of various forms of intracellular CLU have led to further and even contradictory functions. To untangle the current state of knowledge of CLU, this review will combine old views in the field, with new discoveries to highlight the nature and function of this fascinating protein(s). In this review, we further describe the expression and subcellular location of various CLU forms. Moreover, we discuss recent insights into the structure of CLU and assess how structural properties as well as the redox environment determine the chaperone activity of CLU. Eventually, the review connects the biochemistry and molecular cell biology of CLU with medical aspects, to formulate a hypothesis of a CLU function in health and disease.
[Mh] Termos MeSH primário: Clusterina/metabolismo
[Mh] Termos MeSH secundário: Animais
Estruturas Celulares/metabolismo
Clusterina/análise
Clusterina/genética
Clusterina/imunologia
Seres Humanos
Estresse Oxidativo
Conformação Proteica
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Clusterin)
[Em] Mês de entrada:1610
[Cu] Atualização por classe:161230
[Lr] Data última revisão:
161230
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:151218
[St] Status:MEDLINE


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[PMID]:26087973
[Au] Autor:Boyette-Davis JA; Walters ET; Dougherty PM
[Ad] Endereço:Department of Psychology, York College of Pennsylvania, 441 Country Club Road, York, PA 17403, USA.
[Ti] Título:Mechanisms involved in the development of chemotherapy-induced neuropathy.
[So] Source:Pain Manag;5(4):285-96, 2015.
[Is] ISSN:1758-1877
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Chemotherapy-induced peripheral neuropathy (CIPN) is a debilitating and painful condition seen in patients undergoing treatment with common agents such as vincristine, paclitaxel, oxaliplatin and bortezomib. The mechanisms of this condition are diverse, and include an array of molecular and cellular contributions. Current research implicates genetic predispositions to this condition, which then may influence cellular responses to chemotherapy. Processes found to be influenced during CIPN include increased expression of inflammatory mediators, primarily cytokines, which can create cascading effects in neurons and glia. Changes in ion channels and neurotransmission, as well as changes in intracellular signaling and structures have been implicated in CIPN. This review explores these issues and suggests considerations for future research.
[Mh] Termos MeSH primário: Antineoplásicos/efeitos adversos
Neoplasias/tratamento farmacológico
Doenças do Sistema Nervoso Periférico/induzido quimicamente
[Mh] Termos MeSH secundário: Estruturas Celulares/efeitos dos fármacos
Citocinas/efeitos dos fármacos
Citocinas/metabolismo
Seres Humanos
Canais Iônicos/efeitos dos fármacos
Mecanorreceptores/efeitos dos fármacos
Neoplasias/genética
Fibras Nervosas/efeitos dos fármacos
Neuroglia/efeitos dos fármacos
Doenças do Sistema Nervoso Periférico/genética
Transdução de Sinais/efeitos dos fármacos
Transmissão Sináptica/efeitos dos fármacos
Canais de Receptores Transientes de Potencial/efeitos dos fármacos
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Antineoplastic Agents); 0 (Cytokines); 0 (Ion Channels); 0 (Transient Receptor Potential Channels)
[Em] Mês de entrada:1603
[Cu] Atualização por classe:170220
[Lr] Data última revisão:
170220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150620
[St] Status:MEDLINE
[do] DOI:10.2217/pmt.15.19


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[PMID]:25976105
[Au] Autor:Tantos A; Kalmar L; Tompa P
[Ad] Endereço:Institute of Enzymology, Research Centre for Natural Sciences of the Hungarian Academy of Sciences, Budapest, Hungary.
[Ti] Título:The role of structural disorder in cell cycle regulation, related clinical proteomics, disease development and drug targeting.
[So] Source:Expert Rev Proteomics;12(3):221-33, 2015 Jun.
[Is] ISSN:1744-8387
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Understanding the molecular mechanisms of the regulation of cell cycle is a central issue in molecular cell biology, due to its fundamental role in the existence of cells. The regulatory circuits that make decisions on when a cell should divide are very complex and particularly subtly balanced in eukaryotes, in which the harmony of many different cells in an organism is essential for life. Several hundred proteins are involved in these processes, and a great deal of studies attests that most of them have functionally relevant intrinsic structural disorder. Structural disorder imparts many functional advantages on these proteins, and we discuss it in detail that it is involved in all key steps from signaling through the cell membrane to regulating transcription of proteins that execute timely responses to an ever-changing environment.
[Mh] Termos MeSH primário: Pontos de Checagem do Ciclo Celular
Estruturas Celulares/metabolismo
Medicina Clínica
Sistemas de Liberação de Medicamentos
Proteômica
[Mh] Termos MeSH secundário: Animais
Doença
Seres Humanos
Transdução de Sinais
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T; REVIEW
[Em] Mês de entrada:1601
[Cu] Atualização por classe:150515
[Lr] Data última revisão:
150515
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150516
[St] Status:MEDLINE
[do] DOI:10.1586/14789450.2015.1042866


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[PMID]:25752226
[Au] Autor:Narumi M; Nishitsuka K; Yamakawa M; Yamashita H
[Ad] Endereço:Department of Ophthalmology and Visual Sciences, Yamagata University Faculty of Medicine, Yamagata, Japan.
[Ti] Título:A survey of vitreous cell components performed using liquid-based cytology.
[So] Source:Acta Ophthalmol;93(5):e386-90, 2015 Aug.
[Is] ISSN:1755-3768
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:PURPOSE: To confirm the efficacy of liquid-based cytology (LBC) method in the observation of vitreous cells in various vitreoretinal diseases in human. METHODS: Vitreous fluid samples from 30 eyes were obtained by 23-gauge 3-port pars plana vitrectomy. After making three ports, we collected vitreous specimen from the core vitreous cavity without infusion. We divided the samples into a quiescent group and an active group based on clinical signs of inflammation. To confirm availability of LBC preparation slides for immunostaining, we also performed immunocytochemistry (ICC) for CD68, RPE65 and DEC-205 (CD205) using LBC slides of 10 cell-rich cases including retinal detachment and endophthalmitis. RESULTS: Using LBC method, small amounts of vitreous cells were observed efficiently. Vitreous cells were observed in inflammatory quiescent cases including macular pucker and macular hole. The number of vitreous cells increased significantly in the cases with clinically active inflammation (2297 versus 207 cells/ml, respectively, p < 0.01, Mann-Whitney U-test). The ICC results showed the presence of CD68(+) cells in all 10 cases. Large numbers of DEC-205(+) cells were observed in one case with infectious endophthalmitis. In the cases with retinal detachment, the predominant cell type was RPE65(+) . Neutrophils and lymphocytes were also observed. CONCLUSIONS: The LBC method makes it possible to examine vitreous specimens easily and efficiently, facilitating the expedient diagnosis of vitreoretinal diseases, and the preparation slides are available for immunocytochemistry. This study also showed that vitreoretinal disease involves the migration of various types of cells including macrophages, neutrophils, lymphocytes, RPE65(+) pigmented cells and DEC-205(+) cells.
[Mh] Termos MeSH primário: Técnicas Citológicas/métodos
Oftalmopatias/diagnóstico
Doenças Retinianas/diagnóstico
Corpo Vítreo/patologia
[Mh] Termos MeSH secundário: Adulto
Idoso
Idoso de 80 Anos ou mais
Antígenos CD/metabolismo
Antígenos de Diferenciação Mielomonocítica/metabolismo
Biomarcadores/metabolismo
Estruturas Celulares/metabolismo
Feminino
Seres Humanos
Técnicas Imunoenzimáticas
Lectinas Tipo C/metabolismo
Masculino
Meia-Idade
Antígenos de Histocompatibilidade Menor
Receptores de Superfície Celular/metabolismo
Estudos Retrospectivos
Vitrectomia
Corpo Vítreo/metabolismo
cis-trans-Isomerases/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Antigens, CD); 0 (Antigens, Differentiation, Myelomonocytic); 0 (Biomarkers); 0 (CD68 antigen, human); 0 (DEC-205 receptor); 0 (Lectins, C-Type); 0 (Minor Histocompatibility Antigens); 0 (Receptors, Cell Surface); EC 3.1.1.64 (retinoid isomerohydrolase); EC 5.2.- (cis-trans-Isomerases)
[Em] Mês de entrada:1602
[Cu] Atualização por classe:161125
[Lr] Data última revisão:
161125
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150311
[St] Status:MEDLINE
[do] DOI:10.1111/aos.12623



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