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[PMID]:28341448
[Au] Autor:Morishita K; Anh Suong DN; Yoshida H; Yamaguchi M
[Ad] Endereço:Department of Applied Biology, The Center for Advanced Insect Research, Kyoto Institute of Technology, Matsugasaki, Sakyo-ku, Kyoto 606-8585, Japan.
[Ti] Título:The Drosophila DOCK family protein Sponge is required for development of the air sac primordium.
[So] Source:Exp Cell Res;354(2):95-102, 2017 May 15.
[Is] ISSN:1090-2422
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Dedicator of cytokinesis (DOCK) family genes are known as DOCK1-DOCK11 in mammals. DOCK family proteins mainly regulate actin filament polymerization and/or depolymerization and are GEF proteins, which contribute to cellular signaling events by activating small G proteins. Sponge (Spg) is a Drosophila counterpart to mammalian DOCK3/DOCK4, and plays a role in embryonic central nervous system development, R7 photoreceptor cell differentiation, and adult thorax development. In order to conduct further functional analyses on Spg in vivo, we examined its localization in third instar larval wing imaginal discs. Immunostaining with purified anti-Spg IgG revealed that Spg mainly localized in the air sac primordium (ASP) in wing imaginal discs. Spg is therefore predicted to play an important role in the ASP. The specific knockdown of Spg by the breathless-GAL4 driver in tracheal cells induced lethality accompanied with a defect in ASP development and the induction of apoptosis. The monitoring of ERK signaling activity in wing imaginal discs by immunostaining with anti-diphospho-ERK IgG revealed reductions in the ERK signal cascade in Spg knockdown clones. Furthermore, the overexpression of D-raf suppressed defects in survival and the proliferation of cells in the ASP induced by the knockdown of Spg. Collectively, these results indicate that Spg plays a critical role in ASP development and tracheal cell viability that is mediated by the ERK signaling pathway.
[Mh] Termos MeSH primário: Sacos Aéreos/crescimento & desenvolvimento
Sacos Aéreos/metabolismo
Proteínas de Transporte/metabolismo
Proteínas de Drosophila/metabolismo
Drosophila melanogaster/crescimento & desenvolvimento
Drosophila melanogaster/metabolismo
[Mh] Termos MeSH secundário: Sacos Aéreos/citologia
Sacos Aéreos/enzimologia
Animais
Apoptose
Membrana Celular/metabolismo
Citoplasma/metabolismo
Drosophila melanogaster/citologia
MAP Quinases Reguladas por Sinal Extracelular/metabolismo
Técnicas de Silenciamento de Genes
Sistema de Sinalização das MAP Quinases
Traqueia/citologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Carrier Proteins); 0 (Drosophila Proteins); 0 (sponge protein, Drosophila); EC 2.7.11.24 (Extracellular Signal-Regulated MAP Kinases)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170713
[Lr] Data última revisão:
170713
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170326
[St] Status:MEDLINE


  2 / 1134 MEDLINE  
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[PMID]:28224653
[Au] Autor:Cullin CO; Colgin LM; Lewis AD
[Ad] Endereço:Oregon National Primate Research Center, Beaverton, OR, USA.
[Ti] Título:Air sacculitis in three rhesus macaques (Macaca mulatta) and one Japanese macaque (M. fuscata).
[So] Source:J Med Primatol;46(2):48-50, 2017 Apr.
[Is] ISSN:1600-0684
[Cp] País de publicação:Denmark
[La] Idioma:eng
[Ab] Resumo:Bacterial infection of the laryngeal air sacs (air sacculitis) is infrequently reported in nonhuman primates, where it leads to chronic respiratory disease. It is particularly uncommon in macaques; however, we report here suppurative air sacculitis with extension to adjacent cervical tissues in three rhesus macaques and one Japanese macaque. Staphylococcus aureus, Streptococcus sp., and an anaerobic bacterium were isolated.
[Mh] Termos MeSH primário: Sacos Aéreos/patologia
Macaca
Doenças dos Macacos/patologia
Infecções Respiratórias/veterinária
Infecções Estafilocócicas/veterinária
Infecções Estreptocócicas/veterinária
[Mh] Termos MeSH secundário: Sacos Aéreos/microbiologia
Animais
Feminino
Macaca mulatta
Masculino
Doenças dos Macacos/microbiologia
Infecções Respiratórias/microbiologia
Infecções Respiratórias/patologia
Infecções Estafilocócicas/microbiologia
Infecções Estafilocócicas/patologia
Staphylococcus aureus/isolamento & purificação
Infecções Estreptocócicas/microbiologia
Infecções Estreptocócicas/patologia
Streptococcus/isolamento & purificação
[Pt] Tipo de publicação:CASE REPORTS
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170918
[Lr] Data última revisão:
170918
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170223
[St] Status:MEDLINE
[do] DOI:10.1111/jmp.12257


  3 / 1134 MEDLINE  
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[PMID]:28111744
[Au] Autor:Tellechea JS; Fine ML; Norbis W
[Ad] Endereço:Instituto de Biología, Departamento de Biología Animal, Laboratorio de Fisiología de la Reproducción y Ecología de Peces, Facultad de Ciencias, Universidad de la Republica, Igua 4227, Montevideo, Uruguay.
[Ti] Título:Passive acoustic monitoring, development of disturbance calls and differentiation of disturbance and advertisement calls in the Argentine croaker Umbrina canosai (Sciaenidae).
[So] Source:J Fish Biol;90(4):1631-1643, 2017 Apr.
[Is] ISSN:1095-8649
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Disturbance and advertisement calls of the Argentine croaker Umbrina canosai were recorded from coastal Uruguayan waters. Dissections indicate typical sciaenid extrinsic swimbladder muscles present exclusively in males. Disturbance calls were produced when captive U. canosai were startled, chased with a net or grabbed by the tail. Calls were unusual for sciaenids because each pulse consisted of multiple cycles. The number of cycles per pulse and dominant frequency did not change with U. canosai size, but pulse duration and interpulse interval increased. Advertisement calls were recorded from unseen choruses in the field and confirmed with captive individuals in a large tank. Advertisement calls were recorded throughout the known range of the species in Uruguay indicating a continuous belt of spawning populations. Tank recordings of the same individuals permitted explicit comparisons between the two calls. Advertisement call pulses averaged 2·4 more cycles (11·0-8·6) although pulses of both calls were basically similar as were durations and dominant frequencies. Pulse number, however, differed markedly, averaging 13·6 and 3·4 pulses for disturbance and advertisement calls respectively. Furthermore, disturbance calls were produced as a rapid series with an interpulse interval of 26-31 ms whereas advertisement call patterns were less stereotyped and ranged from <100 to 450 ms. Multicycle pulses distinguished U. canosai from other sympatric sciaenids.
[Mh] Termos MeSH primário: Perciformes/fisiologia
Vocalização Animal/fisiologia
[Mh] Termos MeSH secundário: Acústica
Sacos Aéreos
Animais
Masculino
Músculos
Especificidade da Espécie
Uruguai
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170925
[Lr] Data última revisão:
170925
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170124
[St] Status:MEDLINE
[do] DOI:10.1111/jfb.13257


  4 / 1134 MEDLINE  
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[PMID]:27878390
[Au] Autor:Hintzen J; Thielebein J; Daugschies A; Schmäschke R
[Ad] Endereço:Institute for Parasitology, Faculty for Veterinary Medicine, University of Leipzig, Leipzig, Germany. juliane.hintzen@vetmed.uni-leipzig.de.
[Ti] Título:Trematodes from the Northern Lapwing, Vanellus vanellus (Charadriidae), from Central Germany.
[So] Source:Parasitol Res;116(2):661-666, 2017 Feb.
[Is] ISSN:1432-1955
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:Seventy-five previously frozen Northern Lapwings, Vanellus vanellus (Linnaeus, 1758) were dissected and examined for trematodes. The available birds were euthanized after suffering severe injuries from a hail storm. Trematode specimens were found in the air sacs, body cavities and kidneys. They were cleared, stained in Alaun-Carmine and examined via light microscopy. Trematodes were assigned to two different families and three different species: Uvitellina vanelli and Selfcoelum sp. from the family Cyclocoelidae and Tanaisia valida of the family Eucotylidae. A prevalence of 12% (for both, Cyclocoelid and Eucotylid infections) was detected. While trematodes of the respiratory system have been discovered in V. vanellus before, the present study describes renal trematodiasis in this bird species for the first time. Furthermore, the first recovering of a trematode of the species Selfcoelum sp. in the Northern Lapwing is described. Full measurements and figures of trematodes are given. Criteria and critical points in specifying and recovering the parasites are discussed.
[Mh] Termos MeSH primário: Sacos Aéreos/parasitologia
Charadriiformes/parasitologia
Rim/parasitologia
Trematódeos/anatomia & histologia
Trematódeos/classificação
Infecções por Trematódeos/veterinária
[Mh] Termos MeSH secundário: Animais
Alemanha
Infecções por Trematódeos/parasitologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1705
[Cu] Atualização por classe:171007
[Lr] Data última revisão:
171007
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161124
[St] Status:MEDLINE
[do] DOI:10.1007/s00436-016-5330-9


  5 / 1134 MEDLINE  
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[PMID]:27859297
[Au] Autor:Atsumi K; Song HY; Senou H; Inoue K; Mabuchi K
[Ad] Endereço:Atmosphere and Ocean Research Institute, The University of Tokyo, 5-1-5 Kashiwanoha, Kashiwa, Chiba, 277-8564, Japan.
[Ti] Título:Morphological features of an endangered Japanese strain of Cyprinus carpio: reconstruction based on seven SNP markers.
[So] Source:J Fish Biol;90(3):936-953, 2017 Mar.
[Is] ISSN:1095-8649
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Morphological analyses of 183 specimens of Japanese common carp Cyprinus carpio (171 from Lake Biwa and 12 from nursery ponds) using genetic hybrid indices demonstrated that the typical native Japanese strain of C. carpio has a more elongate body, more branched dorsal-fin rays, fewer and shorter gill rakers, more developed pneumatic bulb, more coiled pneumatic duct, longer posterior swimbladder and shorter intestine than the typical introduced C. carpio. These results provide a basis for a better understanding of the ecological characteristics and taxonomic status of the endangered Japanese strain of C. carpio.
[Mh] Termos MeSH primário: Carpas/anatomia & histologia
Carpas/genética
Espécies em Perigo de Extinção
Marcadores Genéticos
Polimorfismo de Nucleotídeo Único/genética
[Mh] Termos MeSH secundário: Sacos Aéreos
Nadadeiras de Animais
Animais
Carpas/classificação
Brânquias
Hibridização Genética
Intestinos
Japão
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Genetic Markers)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170626
[Lr] Data última revisão:
170626
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161119
[St] Status:MEDLINE
[do] DOI:10.1111/jfb.13213


  6 / 1134 MEDLINE  
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[PMID]:27802144
[Au] Autor:Parmentier E; Raick X; Lecchini D; Boyle K; Van Wassenbergh S; Bertucci F; Kéver L
[Ad] Endereço:Université de Liège, Laboratoire de Morphologie Fonctionnelle et Evolutive, AFFISH-RC, Institut de Chimie - B6C, Sart Tilman, Liège 4000, Belgium E.Parmentier@ulg.ac.be.
[Ti] Título:Unusual sound production mechanism in the triggerfish Rhinecanthus aculeatus (Balistidae).
[So] Source:J Exp Biol;220(Pt 2):186-193, 2017 01 15.
[Is] ISSN:1477-9145
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:The ability to produce sound has been known for decades in Balistidae. Sounds of many species have been recorded and a variety of sound-producing mechanisms have been proposed, including teeth stridulation, collision of the buccal teeth and movements of the fins. The best-supported hypothesis involves movements of the pectoral fin against the lateral part of the swimbladder, called a drumming membrane. In this study, we describe for the first time the sounds made by the blackbar triggerfish Rhinecanthus aculeatus, which are like short drum rolls with an average duration of 85 ms, 193 Hz dominant frequency and 136 dB SPL level at 3 cm distance. The sounds are a series of pulses that result from alternate sweeping movements of the right and left pectoral fins, which push a system of three scutes that are forced against the swimbladder wall. Pulses from each fin occur in consecutive pairs. High-speed videos indicate that each pulse consists of two cycles. The first part of each cycle corresponds to the inward buckling of the scutes, whereas the second part of the cycle corresponds to an apparent passive recoil of the scutes and swimbladder wall. This novel sound production mechanism is probably found in many members of Balistidae because these peculiar scutes occur in other species in the family. Comparison of sound characteristics from fishes of different sizes shows that dominant frequency decreases with size in juveniles but not in adults.
[Mh] Termos MeSH primário: Comunicação Animal
Tetraodontiformes/fisiologia
[Mh] Termos MeSH secundário: Sacos Aéreos/fisiologia
Nadadeiras de Animais/fisiologia
Animais
Movimento
Polinésia
Som
Espectrografia do Som/veterinária
Gravação em Vídeo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170922
[Lr] Data última revisão:
170922
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161102
[St] Status:MEDLINE
[do] DOI:10.1242/jeb.146514


  7 / 1134 MEDLINE  
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[PMID]:27380938
[Au] Autor:Gaurav Kumar P; Nidheesh T; Govindaraju K; Jyoti; Suresh PV
[Ad] Endereço:Academy of Scientific and Innovative Research, CSIR-Central Food Technological Research Institute, Mysuru, 570020, India.
[Ti] Título:Enzymatic extraction and characterisation of a thermostable collagen from swim bladder of rohu (Labeo rohita).
[So] Source:J Sci Food Agric;97(5):1451-1458, 2017 Mar.
[Is] ISSN:1097-0010
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: The fish swim bladder is considered as a potential source of realistic collagen. Currently, processing of the Indian major carp rohu (Labeo rohita) generates an enormous quantity of non-edible by-products, including swim bladders, which are discarded as waste with no commercial value. In the present study, collagen was prepared from rohu swim bladder and its physicochemical and fibril-forming capacities were assessed. RESULTS: The collagen isolated from rohu swim bladder was characterised as type I, containing α1 and α2 chains with triple helical structure by sodium dodecyl sulfate-polyacrylamide gel electrophoresis, fourier transform infrared spectroscopy and amino acid analysis. The extracted collagen denaturation temperature was found to be 42.16 °C by differential scanning calorimetry analysis and also exhibited a high solubility in the presence of low NaCl concentrations (0-0.6 mol L ). The extracted collagen exhibited a high fibril-formation capacity at a NaCl concentration of 1.5 mol L . Examination of the microstructure of collagen by scanning electron microscopy (SEM) showed a porous, sheet-like film and a multilayered structure. The fibril formation capacity of collagen was also confirmed using SEM analysis. CONCLUSION: The rohu swim bladder type I collagen was successfully extracted using an enzymatic method with a yield of 465.2 g kg (dry weight basis) and was characterised as a well maintained triple helical structure. The extracted collagen exhibited a high fibril-forming ability. The results of the present study confirm that utilisation of rohu swim bladder will open up a new avenue for the better disposal of by-products and also help to minimise environmental pollution issues. © 2016 Society of Chemical Industry.
[Mh] Termos MeSH primário: Sacos Aéreos/química
Carpas
Colágeno Tipo I/química
[Mh] Termos MeSH secundário: Aminoácidos/análise
Animais
Colágeno Tipo I/isolamento & purificação
Colágeno Tipo I/ultraestrutura
Eletroforese em Gel de Poliacrilamida
Proteínas de Peixes/química
Microscopia Eletrônica de Varredura
Estrutura Secundária de Proteína
Espectroscopia de Infravermelho com Transformada de Fourier
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Amino Acids); 0 (Collagen Type I); 0 (Fish Proteins)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170906
[Lr] Data última revisão:
170906
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160707
[St] Status:MEDLINE
[do] DOI:10.1002/jsfa.7884


  8 / 1134 MEDLINE  
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[PMID]:27983570
[Au] Autor:Zhao YQ; Zeng L; Yang ZS; Huang FF; Ding GF; Wang B
[Ad] Endereço:Zhejiang Provincial Engineering Technology Research Center of Marine Biomedical Products, School of Food and Pharmacy, Zhejiang Ocean University, 1st Haidanan Road, Changzhi Island, Lincheng, Zhoushan 316022, China. zhaoy@hotmail.com.
[Ti] Título:Anti-Fatigue Effect by Peptide Fraction from Protein Hydrolysate of Croceine Croaker (Pseudosciaena crocea) Swim Bladder through Inhibiting the Oxidative Reactions including DNA Damage.
[So] Source:Mar Drugs;14(12), 2016 Dec 13.
[Is] ISSN:1660-3397
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:The swim bladder of the croceine croaker ( ) was believed to have good curative effects in various diseases, including amnesia, insomnia, dizziness, anepithymia, and weakness after giving birth, in traditional Chinese medicine. However, there is no research focusing on the antioxidant and anti-fatigue peptides from croceine croaker swim bladders at present. Therefore, the purpose of this study was to investigate the bioactivities of peptide fractions from the protein hydrolysate of croceine croaker related to antioxidant and anti-fatigue effects. In the study, swim bladder peptide fraction (SBP-III-3) was isolated from the protein hydrolysate of the croceine croaker, and its antioxidant and anti-fatigue activities were measured using in vitro and in vivo methods. The results indicated that SBP-III-3 exhibited good scavenging activities on hydroxyl radicals (HO•) (EC (the concentration where a sample caused a 50% decrease of the initial concentration of HO•) = 0.867 mg/mL), 2,2-diphenyl-1-picrylhydrazyl radicals (DPPH•) (EC = 0.895 mg/mL), superoxide anion radical ( O 2 - •) (EC = 0.871 mg/mL), and 2,2'-azino-bis-3-ethylbenzothiazoline-6-sulfonic acid radical (ABTS⁺•) (EC = 0.346 mg/mL). SBP-III-3 also showed protective effects on DNA damage in a concentration-effect manner and prolonged the swimming time to exhaustion of Institute of Cancer Research (ICR) mice by 57.9%-107.5% greater than that of the control. SBP-III-3 could increase the levels of muscle glucose (9.4%-115.2% increase) and liver glycogen (35.7%-157.3%), and decrease the levels of blood urea nitrogen (BUN), lactic acid (LA), and malondialdehyde (MDA) by 16.4%-22.4%, 13.9%-20.1%, and 28.0%-53.6%, respectively. SBP-III-3 also enhanced the activity of lactic dehydrogenase to scavenge excessive LA for slowing the development of fatigue. In addition, SBP-III-3 increased the activities superoxide dismutase, catalase, and glutathione peroxidase to reduce the reactive oxygen species (ROS) damage in mice. In conclusion, SBP-III-3 possessed good anti-fatigue capacities on mice by inhibiting the oxidative reactions and provided an important basis for developing the swim bladder peptide functional food.
[Mh] Termos MeSH primário: Sacos Aéreos/química
Dano ao DNA/efeitos dos fármacos
Fadiga/tratamento farmacológico
Peptídeos/farmacologia
Perciformes/metabolismo
Hidrolisados de Proteína/química
Espécies Reativas de Oxigênio/metabolismo
[Mh] Termos MeSH secundário: Animais
Antioxidantes/metabolismo
Compostos de Bifenilo/química
Catalase/metabolismo
Glutationa Peroxidase/metabolismo
Radical Hidroxila/metabolismo
Peroxidação de Lipídeos/efeitos dos fármacos
Masculino
Malondialdeído/metabolismo
Camundongos
Camundongos Endogâmicos ICR
Peptídeos/química
Picratos/química
Superóxido Dismutase/metabolismo
Superóxidos/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antioxidants); 0 (Biphenyl Compounds); 0 (Peptides); 0 (Picrates); 0 (Protein Hydrolysates); 0 (Reactive Oxygen Species); 11062-77-4 (Superoxides); 3352-57-6 (Hydroxyl Radical); 4Y8F71G49Q (Malondialdehyde); DFD3H4VGDH (1,1-diphenyl-2-picrylhydrazyl); EC 1.11.1.6 (Catalase); EC 1.11.1.9 (Glutathione Peroxidase); EC 1.15.1.1 (Superoxide Dismutase)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170518
[Lr] Data última revisão:
170518
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161217
[St] Status:MEDLINE


  9 / 1134 MEDLINE  
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[PMID]:27831560
[Au] Autor:Zhang Y; Liu H; Yao J; Huang Y; Qin S; Sun Z; Xu Y; Wan S; Cheng H; Li C; Zhang X; Ke Y
[Ad] Endereço:Research Center of Molecular Medicine, Department of Pathology and Pathophysiology, Program in Molecular Cell Biology, Zhejiang University School of Medicine, Hangzhou 310058, China.
[Ti] Título:Manipulating the air-filled zebrafish swim bladder as a neutrophilic inflammation model for acute lung injury.
[So] Source:Cell Death Dis;7(11):e2470, 2016 Nov 10.
[Is] ISSN:2041-4889
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Acute lung injury (ALI) and its more severe form, acute respiratory distress syndrome (ARDS), are life-threatening diseases that are associated with high mortality rates due to treatment limitations. Neutrophils play key roles in the pathogenesis of ALI/ARDS by promoting the inflammation and injury of the alveolar microenvironment. To date, in vivo functional approaches have been limited by the inaccessibility to the alveolar sacs, which are located at the anatomical terminal of the respiratory duct in mammals. We are the first to characterize the swim bladder of the zebrafish larva, which is similar to the mammalian lung, as a real-time in vivo model for examining pulmonary neutrophil infiltration during ALI. We observed that the delivery of exogenous materials, including lipopolysaccharide (LPS), Poly IC and silica nanoparticles, by microinjection triggered significant time- and dose-dependent neutrophil recruitment into the swim bladder. Neutrophils infiltrated the LPS-injected swim bladder through the blood capillaries around the pneumatic duct or a site near the pronephric duct. An increase in the post-LPS inflammatory cytokine mRNA levels coincided with the in vivo neutrophil aggregation in the swim bladder. Microscopic examinations of the LPS-injected swim bladders further revealed in situ injuries, including epithelial distortion, endoplasmic reticulum swelling and mitochondrial injuries. Inhibitor screening assays with this model showed a reduction in neutrophil migration into the LPS-injected swim bladder in response to Shp2 inhibition. Moreover, the pharmacological suppression and targeted disruption of Shp2 in myeloid cells alleviated pulmonary inflammation in the LPS-induced ALI mouse model. Additionally, we used this model to assess pneumonia-induced neutrophil recruitment by microinjecting bronchoalveolar lavage fluid from patients into swim bladders; this injection enhanced neutrophil aggregation relative to the control. In conclusion, our findings highlight the swim bladder as a promising and powerful model for mechanistic and drug screening studies of alveolar injuries.
[Mh] Termos MeSH primário: Lesão Pulmonar Aguda/patologia
Sacos Aéreos/patologia
Ar
Inflamação/patologia
Neutrófilos/patologia
Peixe-Zebra/fisiologia
[Mh] Termos MeSH secundário: Sacos Aéreos/ultraestrutura
Animais
Movimento Celular
Citocinas/metabolismo
Modelos Animais de Doenças
Lipopolissacarídeos
Camundongos
Infiltração de Neutrófilos
Proteína Tirosina Fosfatase não Receptora Tipo 11/deficiência
Proteína Tirosina Fosfatase não Receptora Tipo 11/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Cytokines); 0 (Lipopolysaccharides); EC 3.1.3.48 (Protein Tyrosine Phosphatase, Non-Receptor Type 11)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170828
[Lr] Data última revisão:
170828
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161111
[St] Status:MEDLINE
[do] DOI:10.1038/cddis.2016.365


  10 / 1134 MEDLINE  
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[PMID]:27736228
[Ti] Título:What Is Your Diagnosis?
[So] Source:J Avian Med Surg;30(3):298-302, 2016 Sep.
[Is] ISSN:1082-6742
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Sacos Aéreos
Aspergilose/veterinária
Doenças das Aves/microbiologia
Patos
Infecções Respiratórias/veterinária
[Mh] Termos MeSH secundário: Animais
Aspergilose/patologia
Doenças das Aves/patologia
Doenças das Aves/cirurgia
Evolução Fatal
Masculino
Pneumonia/microbiologia
Pneumonia/patologia
Pneumonia/veterinária
Infecções Respiratórias/microbiologia
Infecções Respiratórias/patologia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1701
[Cu] Atualização por classe:170127
[Lr] Data última revisão:
170127
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161014
[St] Status:MEDLINE



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