Base de dados : MEDLINE
Pesquisa : A14.549.167.860 [Categoria DeCS]
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  1 / 15096 MEDLINE  
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[PMID]:29231027
[Au] Autor:Liu F; Dang YH
[Ad] Endereço:Department of Forensic Science, Health Science Center, Xi'an Jiaotong University, Xi'an 710061, China.
[Ti] Título:[Research Progress on Forensic Dentistry].
[So] Source:Fa Yi Xue Za Zhi;33(2):175-180, 2017 Apr.
[Is] ISSN:1004-5619
[Cp] País de publicação:China
[La] Idioma:chi
[Ab] Resumo:Forensic dentistry is an interdiscipline of forensic medicine and stomatology, which provides legal information by collecting, testing and assessing the dental evidence scientifically. In this review, the present application of forensic dentistry has been described, such as the estimation of age, sex, species, occupation and living habit, as well as the identification of individual, domestic violence or abuse, which aims to enrich and improve forensic dentistry for making it be more useful in forensic medicine even in juridical practice.
[Mh] Termos MeSH primário: Determinação da Idade pelos Dentes
Odontologia Legal/métodos
[Mh] Termos MeSH secundário: Antropologia Forense
Medicina Legal
Seres Humanos
Dente
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180306
[Lr] Data última revisão:
180306
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171213
[St] Status:MEDLINE
[do] DOI:10.3969/j.issn.1004-5619.2017.02.015


  2 / 15096 MEDLINE  
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[PMID]:29292410
[Au] Autor:Mehl A; Bosch G; Fischer C; Ender A
[Ti] Título:In vivo tooth-color measurement with a new 3D intraoral scanning system in comparison to conventional digital and visual color determination methods.
[So] Source:Int J Comput Dent;20(4):343-361, 2017.
[Is] ISSN:1463-4201
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:STATEMENT OF PROBLEM: Three-dimensional (3D) intraoral scanning systems allow for the simultaneous acquisition of 3D information about tooth surfaces and a photorealistic view of the patient's tooth colors. AIM: The goal of this study was the in vivo comparison of a new 3D scanner with a color acquisition mode and conventional visual and digital color measurements. MATERIALS AND METHODS: The colors of 40 teeth of 20 patients were evaluated in seven ways: 1) By dentists using the Vita 3D-Master; 2) By dental technicians using the Vita 3D-Master; 3) With the 3Shape Trios device; 4) With the Vita Easyshade device; 5) With the Vita Easyshade Advance device; 6) With the SpectroShade device; and 7) With the SpectroShade Micro device. Digital measurements of Groups 3 to 7 were repeated three times for each tooth. For all groups, both the CIE Lab values and the Vita 3D-Master values were recorded. The repeatability and relative accuracy of the Vita 3D-Master values were analyzed statistically using Pearson's chi-squared test (α < 0.05). ΔE values were calculated from the CIE Lab values, which served as a basis for performing multidimensional scaling (MDS) and evaluating differences between the groups using the one-way ANOVA with post hoc Tamhane's test (α < 0.05). RESULTS: The results of the ΔE values showed that clinically relevant differences between the evaluation by dentists, dental technicians, and the intraoral scanning device (3Shape) are negligible. The intraoral 3D scanning device (Group 3) and the digital systems (Groups 4 to 7) did not differ significantly in the repeatability of color shade management. The SpectroShade Micro (Group 7) had significantly better relative accuracy than the other devices. CONCLUSIONS: The results demonstrate that intraoral scanning systems can be used to measure both tooth color and tooth surface in 3D. CLINICAL IMPLICATIONS: Intraoral optical scanning devices allow for the acquisition of accurate 3D surface data. Tooth color can be evaluated simultaneously and can be used to determine the color of restorations without requiring additional conventional color-measurement methods.
[Mh] Termos MeSH primário: Cor
Planejamento de Prótese Dentária
Pigmentação em Prótese/instrumentação
Dente/anatomia & histologia
[Mh] Termos MeSH secundário: Colorimetria/instrumentação
Seres Humanos
Fotografia
Espectrofotometria
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180228
[Lr] Data última revisão:
180228
[Sb] Subgrupo de revista:D
[Da] Data de entrada para processamento:180103
[St] Status:MEDLINE


  3 / 15096 MEDLINE  
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Cury, Jaime Aparecido
Tenuta, Lívia Maria Andaló
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[PMID]:29385163
[Au] Autor:Leitão TJ; Cury JA; Tenuta LMA
[Ad] Endereço:Department of Physiological Sciences, Piracicaba Dental School, University of Campinas, Piracicaba, São Paulo, Brazil.
[Ti] Título:Kinetics of calcium binding to dental biofilm bacteria.
[So] Source:PLoS One;13(1):e0191284, 2018.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Dental biofilm bacteria can bind calcium ions and release them during a pH drop, which could decrease the driving force for dental demineralization (i.e. hydroxyapatite dissolution) occurring at reduced pHs. However, the kinetics of this binding and release is not completely understood. Here we validated a method to evaluate the kinetics of calcium binding and release to/from Streptococcus mutans, and estimated the importance of this reservoir as a source of ions. The kinetics of calcium binding was assessed by measuring the amount of bound calcium in S. mutans Ingbrit 1600 pellets treated with PIPES buffer, pH 7.0, containing 1 or 10 mM Ca; for the release kinetics, bacterial pellets previously treated with 1 mM or 10 mM Ca were exposed to the calcium-free or 1 mM Ca PIPES buffer, pH 7.0, for up to 60 min. Binding and release curves were constructed and parameters of kinetics were calculated. Also, calcium release was assessed by exposing pellets previously treated with calcium to a pH 5.0 buffer for 10 min. Calcium binding to bacteria was concentration-dependent and rapid, with maximum binding reached at 5 min. On the other hand, calcium release was slower, and according to the calculations, would never be complete in the groups pretreated with 10 mM Ca. Decreasing pH from 7.0 to 5.0 caused a release of calcium able to increase the surrounding fluid calcium concentration in 2 mM. The results suggest that dental biofilm bacteria may act as a calcium reservoir, rapidly binding ions from surrounding fluids, releasing them slowly at neutral pH and promptly during a pH drop.
[Mh] Termos MeSH primário: Biofilmes
Cálcio/metabolismo
Streptococcus mutans/metabolismo
Dente/microbiologia
[Mh] Termos MeSH secundário: Concentração de Íons de Hidrogênio
Cinética
Streptococcus mutans/fisiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
SY7Q814VUP (Calcium)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180226
[Lr] Data última revisão:
180226
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180201
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0191284


  4 / 15096 MEDLINE  
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[PMID]:28744927
[Au] Autor:Ohara WM; Abrahão VP; Espíndola VC
[Ad] Endereço:Museu de Zoologia da Universidade de São Paulo, Ictiologia Caixa Postal 42494, 04218-970, São Paulo, SP, Brazil.
[Ti] Título:Hyphessobrycon platyodus (Teleostei: Characiformes), a new species from the Rio Madeira basin, Brazil, with comments on how multicuspid teeth relate to feeding habits in Characidae.
[So] Source:J Fish Biol;91(3):835-850, 2017 Sep.
[Is] ISSN:1095-8649
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:A new species of Hyphessobrycon is described from the Rio Juma, a tributary of the lower Rio Aripuanã-Rio Madeira basin, Amazonas, Brazil. Hyphessobrycon platyodus can be distinguished from its congeners by the: presence of an elongated dorsal fin in adult males, 25-28 branched anal-fin rays and absence of dark blotches from the dorsal fin and caudal peduncle. The presence of multicuspid teeth in species of Characidae and its relation with feeding habits are briefly commented on.
[Mh] Termos MeSH primário: Caraciformes/classificação
Comportamento Alimentar
[Mh] Termos MeSH secundário: Animais
Brasil
Caraciformes/anatomia & histologia
Feminino
Masculino
Caracteres Sexuais
Dente/anatomia & histologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180222
[Lr] Data última revisão:
180222
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170727
[St] Status:MEDLINE
[do] DOI:10.1111/jfb.13383


  5 / 15096 MEDLINE  
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[PMID]:29384732
[Au] Autor:Capitaneanu C; Willems G; Thevissen P
[Ad] Endereço:Department of Oral Health Sciences, Forensic Dentistry, KU Leuven.
[Ti] Título:A systematic review of odontological sex estimation methods.
[So] Source:J Forensic Odontostomatol;2(35):1-24, 2017 Dec 01.
[Is] ISSN:2219-6749
[Cp] País de publicação:Australia
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: In human identification sex estimation plays an important role in the search for ante-mortem data. AIM: To systematically review studies describing and testing/validating methods of odontological sex estimation. The set research question was: What odontological sex estimation method is the most accurate? MATERIALS AND METHODS: An electronic search until November 29th 2016 was performed in 5 databases: MEDLINE/PubMed, Cochrane, SciELO, LILACS and Grey literature. The PRISMA guidelines were used. Studies were assessed and included based on the reported data. In particular data criteria were set regarding the considered population, sample size, age range, sex estimation method, type of statistical analysis and study outcome. The extracted data enabled to classify the included studies. Meta-analysis was used to compare the study outcomes per obtained study group. RESULTS: The established search string detected 4720 studies. 103 were considered eligible after review of title, abstract and full-text. The odontological sex estimation methods were classified based on dental metric and non-metric measurements (n=65), cephalometric analysis (n=13), frontal and maxillary sinuses (n=5), cheiloscopy (n=4), palatal features (n=3) and biochemical analysis of teeth (n=13). Teeth measurements for sex estimation were mainly performed on casts (n=34), followed by skeletal remains (n=13), medical imaging (n=5), intraoral measurements/ photography (n=4), and cascades of the above (n=4). CONCLUSION: The variety of published odontological sex estimation methods highlights the importance of sex estimation in human identification. Biochemical analysis of teeth proved to be the most accurate method, but in forensic practice, a need to select the most appropriate evidence based odontological sex estimation method exists.
[Mh] Termos MeSH primário: Odontologia Legal/métodos
Caracteres Sexuais
[Mh] Termos MeSH secundário: Cefalometria
Seres Humanos
Radiografia Dentária
Dente/anatomia & histologia
Dente/química
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180221
[Lr] Data última revisão:
180221
[Sb] Subgrupo de revista:D
[Da] Data de entrada para processamento:180201
[St] Status:MEDLINE


  6 / 15096 MEDLINE  
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[PMID]:29338011
[Au] Autor:Waugh DA; Suydam RS; Ortiz JD; Thewissen JGM
[Ad] Endereço:Department of Anatomy and Neurobiology, Northeast Ohio Medical University, Rootstown, Ohio, United States of America.
[Ti] Título:Validation of Growth Layer Group (GLG) depositional rate using daily incremental growth lines in the dentin of beluga (Delphinapterus leucas (Pallas, 1776)) teeth.
[So] Source:PLoS One;13(1):e0190498, 2018.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Counts of Growth Layer Groups (GLGs) in the dentin of marine mammal teeth are widely used as indicators of age. In most marine mammals, observations document that GLGs are deposited yearly, but in beluga whales, some studies have supported the view that two GLGs are deposited each year. Our understanding of beluga life-history differs substantially depending on assumptions regarding the timing of GLG deposition; therefore, resolving this issue has important considerations for population assessments. In this study, we used incremental lines that represent daily pulses of dentin mineralization to test the hypothesis that GLGs in beluga dentin are deposited on a yearly basis. Our estimate of the number of daily growth lines within one GLG is remarkably close to 365 days within error, supporting the hypothesis that GLGs are deposited annually in beluga. We show that measurement of daily growth increments can be used to validate the time represented by GLGs in beluga. Furthermore, we believe this methodology may have broader applications to age estimation in other taxa.
[Mh] Termos MeSH primário: Beluga
Dentina/crescimento & desenvolvimento
Dente/crescimento & desenvolvimento
[Mh] Termos MeSH secundário: Animais
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T; VALIDATION STUDIES
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180221
[Lr] Data última revisão:
180221
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180117
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0190498


  7 / 15096 MEDLINE  
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[PMID]:29320542
[Au] Autor:Matisoo-Smith E; Gosling AL; Platt D; Kardailsky O; Prost S; Cameron-Christie S; Collins CJ; Boocock J; Kurumilian Y; Guirguis M; Pla Orquín R; Khalil W; Genz H; Abou Diwan G; Nassar J; Zalloua P
[Ad] Endereço:Department of Anatomy, University of Otago, Dunedin, New Zealand.
[Ti] Título:Ancient mitogenomes of Phoenicians from Sardinia and Lebanon: A story of settlement, integration, and female mobility.
[So] Source:PLoS One;13(1):e0190169, 2018.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The Phoenicians emerged in the Northern Levant around 1800 BCE and by the 9th century BCE had spread their culture across the Mediterranean Basin, establishing trading posts, and settlements in various European Mediterranean and North African locations. Despite their widespread influence, what is known of the Phoenicians comes from what was written about them by the Greeks and Egyptians. In this study, we investigate the extent of Phoenician integration with the Sardinian communities they settled. We present 14 new ancient mitogenome sequences from pre-Phoenician (~1800 BCE) and Phoenician (~700-400 BCE) samples from Lebanon (n = 4) and Sardinia (n = 10) and compare these with 87 new complete mitogenomes from modern Lebanese and 21 recently published pre-Phoenician ancient mitogenomes from Sardinia to investigate the population dynamics of the Phoenician (Punic) site of Monte Sirai, in southern Sardinia. Our results indicate evidence of continuity of some lineages from pre-Phoenician populations suggesting integration of indigenous Sardinians in the Monte Sirai Phoenician community. We also find evidence of the arrival of new, unique mitochondrial lineages, indicating the movement of women from sites in the Near East or North Africa to Sardinia, but also possibly from non-Mediterranean populations and the likely movement of women from Europe to Phoenician sites in Lebanon. Combined, this evidence suggests female mobility and genetic diversity in Phoenician communities, reflecting the inclusive and multicultural nature of Phoenician society.
[Mh] Termos MeSH primário: Demografia
Grupos Étnicos/história
Genoma Mitocondrial
Migração Humana/história
Mulheres
[Mh] Termos MeSH secundário: Adolescente
Adulto
Criança
Cultura
DNA Mitocondrial/análise
DNA Mitocondrial/isolamento & purificação
Grupos Étnicos/genética
Feminino
Variação Genética
Haplótipos
História Antiga
Seres Humanos
Itália
Líbano/etnologia
Região do Mediterrâneo
Filogenia
Dinâmica Populacional
Dente
[Pt] Tipo de publicação:HISTORICAL ARTICLE; JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (DNA, Mitochondrial)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180214
[Lr] Data última revisão:
180214
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180111
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0190169


  8 / 15096 MEDLINE  
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[PMID]:29178643
[Au] Autor:Yuan Q; Zhao M; Tandon B; Maili L; Liu X; Zhang A; Baugh EH; Tran T; Silva RM; Hecht JT; Swindell EC; Wagner DS; Letra A
[Ad] Endereço:Department of Pediatrics, University of Texas Health Science Center at Houston Medical School, Houston, Texas.
[Ti] Título:Role of WNT10A in failure of tooth development in humans and zebrafish.
[So] Source:Mol Genet Genomic Med;5(6):730-741, 2017 11.
[Is] ISSN:2324-9269
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Oligodontia is a severe form of tooth agenesis characterized by the absence of six or more permanent teeth. Oligodontia has complex etiology and variations in numerous genes have been suggested as causal for the condition. METHODS: We applied whole-exome sequencing (WES) to identify the cause of oligodontia in a 9-year-old girl missing 11 permanent teeth. Protein modeling and functional analysis in zebrafish were also performed to understand the impact of identified variants on the phenotype. RESULTS: We identified a novel compound heterozygous missense mutation in WNT10A (c.637G>A:p.Gly213Ser and c.1070C>T:p.Thr357Ile) as the likely cause of autosomal recessive oligodontia in the child. Affected residues are located in conserved regions and variants are predicted to be highly deleterious for potentially destabilizing the protein fold and inhibiting normal protein function. Functional studies in zebrafish embryos showed that wnt10a is expressed in the craniofacies at critical time points for tooth development, and that perturbations of wnt10a expression impaired normal tooth development and arrested tooth development at 5 days postfertilization (dpf). Furthermore, mRNA expression levels of additional tooth development genes were directly correlated with wnt10a expression; expression of msx1, dlx2b, eda, and axin2 was decreased upon wnt10a knockdown, and increased upon wnt10a overexpression. CONCLUSIONS: Our results reveal a novel compound heterozygous variant in WNT10A as pathogenic for oligodontia, and demonstrate that perturbations of wnt10a expression in zebrafish may directly and/or indirectly affect tooth development recapitulating the agenesis phenotype observed in humans.
[Mh] Termos MeSH primário: Anodontia/genética
Dente/crescimento & desenvolvimento
Proteínas Wnt/genética
Proteínas de Peixe-Zebra/genética
[Mh] Termos MeSH secundário: Sequência de Aminoácidos
Animais
Animais Geneticamente Modificados/genética
Anodontia/diagnóstico
Sequência de Bases
Criança
Dentição Permanente
Embrião não Mamífero/metabolismo
Feminino
Heterozigoto
Seres Humanos
Modelos Animais
Morfolinos/genética
Morfolinos/metabolismo
Fenótipo
Estrutura Terciária de Proteína
Dente/patologia
Sequenciamento Completo do Exoma
Proteínas Wnt/química
Proteínas Wnt/metabolismo
Peixe-Zebra/genética
Proteínas de Peixe-Zebra/antagonistas & inibidores
Proteínas de Peixe-Zebra/metabolismo
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Morpholinos); 0 (WNT10A protein, human); 0 (Wnt Proteins); 0 (Zebrafish Proteins)
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180207
[Lr] Data última revisão:
180207
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171128
[St] Status:MEDLINE
[do] DOI:10.1002/mgg3.332


  9 / 15096 MEDLINE  
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[PMID]:29274551
[Au] Autor:Koarai K; Kino Y; Takahashi A; Suzuki T; Shimizu Y; Chiba M; Osaka K; Sasaki K; Urushihara Y; Fukuda T; Isogai E; Yamashiro H; Oka T; Sekine T; Fukumoto M; Shinoda H
[Ad] Endereço:Department of Chemistry, Tohoku University, Japan.
[Ti] Título:Sr specific activity of teeth of abandoned cattle after the Fukushima accident - teeth as an indicator of environmental pollution.
[So] Source:J Environ Radioact;183:1-6, 2018 Mar.
[Is] ISSN:1879-1700
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Sr specific activity in the teeth of young cattle that were abandoned in Kawauchi village and Okuma town located in the former evacuation areas of the Fukushima-Daiichi Nuclear Power Plant (FNPP) accident were measured. Additionally, specific activity in contaminated surface soils sampled from the same area was measured. (1) All cattle teeth examined were contaminated with Sr. The specific activity, however, varied depending on the developmental stage of the teeth during the FNPP accident; teeth that had started development before the accident exhibited comparatively lower values, while teeth developed mainly after the accident showed higher values. (2) Values of Sr-specific activity in teeth formed after the FNPP accident were higher than those of the bulk soil but similar to those in the exchangeable fraction (water and CH COONH soluble fractions) of the soil. The findings suggest that Sr was incorporated into the teeth during the process of development, and that Sr in the soluble and/or leachable fractions of the soil might migrate into teeth and contribute to the amount of Sr in the teeth. Thus, the concentration of Sr in teeth formed after the FNPP accident might reflect the extent of Sr pollution in the environment.
[Mh] Termos MeSH primário: Acidente Nuclear de Fukushima
Monitoramento de Radiação/métodos
Radioisótopos de Estrôncio/análise
Dente/química
[Mh] Termos MeSH secundário: Animais
Bovinos
Japão
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Strontium Radioisotopes)
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180130
[Lr] Data última revisão:
180130
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171224
[St] Status:MEDLINE


  10 / 15096 MEDLINE  
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[PMID]:27771467
[Au] Autor:Juras A; Chylenski M; Krenz-Niedbala M; Malmström H; Ehler E; Pospieszny L; Lukasik S; Bednarczyk J; Piontek J; Jakobsson M; Dabert M
[Ad] Endereço:Department of Human Evolutionary Biology, Institute of Anthropology, Faculty of Biology, Adam Mickiewicz University in Poznan, Umultowska 89, 61-614 Poznan, Poland. Electronic address: annaj@amu.edu.pl.
[Ti] Título:Investigating kinship of Neolithic post-LBK human remains from Krusza Zamkowa, Poland using ancient DNA.
[So] Source:Forensic Sci Int Genet;26:30-39, 2017 01.
[Is] ISSN:1878-0326
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:We applied an interdisciplinary approach to investigate kinship patterns and funerary practices during the middle Neolithic. Genetic studies, radiocarbon dating, and taphonomic analyses were used to examine two grave clusters from Krusza Zamkowa, Poland. To reconstruct kinship and determine biological sex, we extracted DNA from bones and teeth, analyzed mitochondrial genomes and nuclear SNPs using the HID-Ion AmpliSeq™ Identity panel generated on Illumina and Ion Torrent platforms, respectively. We further dated the material (AMS C) and to exclude aquatic radiocarbon reservoir effects, measures of carbon and nitrogen stable isotopes for diet reconstruction were used. We found distinct mitochondrial genomes belonging to haplogroups U5b2a1a, K1c and H3d in the first grave cluster, and excluded maternal kin patterns among the three analyzed individuals. In the second grave cluster one individual belonged to K1a4. However, we could not affiliate the second individual to a certain haplogroup due to the fragmented state of the mitochondrial genome. Although the individuals from the second grave cluster differ at position 6643, we believe that more data is needed to fully resolve this issue. We retrieved between 26 and 77 autosomal SNPs from three of the individuals. Based on kinship estimations, taking into account the allelic dropout distribution, we could not exclude first degree kin relation between the two individuals from the second grave cluster. We could, however, exclude a first degree kinship between these two individuals and an individual from the first grave cluster. Presumably, not only biological kinship, but also social relations played an important role in the funerary practice during this time period. We further conclude that the HID-Ion AmpliSeq™ Identity Panel may prove useful for first degree kin relation studies for samples with good DNA preservation, and that mitochondrial genome capture enrichment is a powerful tool for excluding direct maternal relationship in ancient individuals.
[Mh] Termos MeSH primário: DNA Antigo
DNA Mitocondrial/genética
Linhagem
[Mh] Termos MeSH secundário: Osso e Ossos/química
Isótopos de Carbono
Feminino
Genótipo
Sequenciamento de Nucleotídeos em Larga Escala
Seres Humanos
Masculino
Isótopos de Nitrogênio
Polônia
Reação em Cadeia da Polimerase
Polimorfismo de Nucleotídeo Único
Análise para Determinação do Sexo
Dente/química
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Carbon Isotopes); 0 (DNA, Ancient); 0 (DNA, Mitochondrial); 0 (Nitrogen Isotopes)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:180129
[Lr] Data última revisão:
180129
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161107
[St] Status:MEDLINE



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