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[PMID]:28887018
[Au] Autor:Kim M; Minoux M; Piaia A; Kueng B; Gapp B; Weber D; Haller C; Barbieri S; Namoto K; Lorenz T; Wirsching J; Bassilana F; Dietrich W; Rijli FM; Ksiazek I
[Ad] Endereço:Novartis Institute for Biomedical Research, CH-4056 Basel, Switzerland.
[Ti] Título:DPP9 enzyme activity controls survival of mouse migratory tongue muscle progenitors and its absence leads to neonatal lethality due to suckling defect.
[So] Source:Dev Biol;431(2):297-308, 2017 11 15.
[Is] ISSN:1095-564X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Dipeptidyl peptidase 9 (DPP9) is an intracellular N-terminal post-proline-cleaving enzyme whose physiological function remains largely unknown. We investigated the role of DPP9 enzyme in vivo by characterizing knock-in mice expressing a catalytically inactive mutant form of DPP9 (S729A; DPP9 mice). We show that DPP9 mice die within 12-18h after birth. The neonatal lethality can be rescued by manual feeding, indicating that a suckling defect is the primary cause of neonatal lethality. The suckling defect results from microglossia, and is characterized by abnormal formation of intrinsic muscles at the distal tongue. In DPP9 mice, the number of occipital somite-derived migratory muscle progenitors, forming distal tongue intrinsic muscles, is reduced due to increased apoptosis. In contrast, intrinsic muscles of the proximal tongue and extrinsic tongue muscles, which derive from head mesoderm, develop normally in DPP9 mice. Thus, lack of DPP9 activity in mice leads to impaired tongue development, suckling defect and subsequent neonatal lethality due to impaired survival of a specific subset of migratory tongue muscle progenitors.
[Mh] Termos MeSH primário: Dipeptidil Peptidases e Tripeptidil Peptidases/metabolismo
Músculo Esquelético/citologia
Células-Tronco/citologia
Células-Tronco/enzimologia
Língua/citologia
[Mh] Termos MeSH secundário: Alanina/genética
Animais
Animais Recém-Nascidos
Animais Lactentes
Domínio Catalítico
Contagem de Células
Sobrevivência Celular
Camundongos
Camundongos Transgênicos
Desenvolvimento Muscular
Proteínas Musculares/metabolismo
Mutação Puntual/genética
Receptores CXCR4/metabolismo
Serina/genética
Doenças da Língua/patologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (CXCR4 protein, mouse); 0 (Lbx1h protein, mouse); 0 (Muscle Proteins); 0 (Receptors, CXCR4); 452VLY9402 (Serine); EC 3.4.14.- (Dipeptidyl-Peptidases and Tripeptidyl-Peptidases); EC 3.4.14.5 (dipeptidyl peptidase 9, mouse); OF5P57N2ZX (Alanine)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171111
[Lr] Data última revisão:
171111
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170910
[St] Status:MEDLINE


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[PMID]:28525335
[Au] Autor:Balan BJ; Skopinska-Rózewska E; Skopinski P; Zdanowski R; Lesniak M; Kiepura A; Lewicki S
[Ad] Endereço:.
[Ti] Título:Morphometric abnormalities in the spleen of the progeny of mice fed epigallocatechin during gestation and nursing.
[So] Source:Pol J Vet Sci;20(1):5-12, 2017 Mar 28.
[Is] ISSN:1505-1773
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:It is very difficult to cure pregnant females suffering from infections, because of the risk which might occur during treatment by several, even herbal, medications. Many of these substances, among them extracts from plants, have antimicrobial, anti-inflammatory and immunostimulatory properties owing to their polyphenols content, but also may reveal unwanted effects on the fetal development because of their anti-angiogenic properties. The aim of the present study was to elucidate whether daily feeding pregnant and nursing mice 0.2 mg/kg epigallocatechin (EGC), previously recognized as angiogenesis inhibitor, may lead to abnormalities in morphology of spleen and in some parameters of immune function of their adult, 6-week old progeny. Morphometry of EGC offspring spleens revealed lower number of lymphatic nodules and their larger diameter than those found in the control offspring. Cellularity of spleens was lower in EGC offspring than in the controls. Cytometric analysis showed that this decline concerns lymphocytes with CD335 (p<0.001), CD19 (p<0.01) and CD4 (p<0.05) markers. No differences were observed in the humoral response to the immunization with SRBC, and in the proliferative response of splenocytes to mitogens PHA, ConA and LPS.
[Mh] Termos MeSH primário: Catequina/análogos & derivados
Baço/efeitos dos fármacos
Baço/patologia
[Mh] Termos MeSH secundário: Anormalidades Induzidas por Medicamentos
Animais
Animais Recém-Nascidos
Animais Lactentes
Antígenos CD2/imunologia
Catequina/toxicidade
Eritrócitos/metabolismo
Feminino
Lactação
Camundongos
Camundongos Endogâmicos BALB C
Gravidez
Complicações na Gravidez
Ovinos/sangue
Baço/citologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (CD2 Antigens); 7Z197MG6QL (gallocatechol); 8R1V1STN48 (Catechin)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170520
[St] Status:MEDLINE


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[PMID]:28495192
[Au] Autor:de Melo GKA; Ítavo CCBF; Monteiro KLS; da Silva JA; da Silva PCG; Ítavo LCV; Borges DGL; de Almeida Borges F
[Ad] Endereço:Faculdade de Medicina Veterinária e Zootecnia, Universidade Federal de Mato Grosso do Sul, Avenida Senador Filinto Müller, 2,443, Campo Grande, CEP 79074-460, Mato Grosso do Sul, Brazil. Electronic address: gleiceayardes@gmail.com.
[Ti] Título:Effect of creep-fed supplement on the susceptibility of pasture-grazed suckling lambs to gastrointestinal helminths.
[So] Source:Vet Parasitol;239:26-30, 2017 May 30.
[Is] ISSN:1873-2550
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:This study evaluated the effect of creep feeding a protein supplement on the susceptibility of suckling lambs to infection with gastrointestinal helminths. Male and female lambs were grazed on Brachiaria spp. pastures next to their mothers. Animals were allocated to one of two treatments: creep feeding (261g/d) and control (no supplementation). The trial period was the suckling of lambs during two years of study: May-October 2013 and March-July 2014. Supplementary creep feeding of lambs improved animal performance (P<0.05). Creep-fed lambs reached 18kg body weight in 64 d, but unsupplemented lambs required 77 d to reach the same weight. Lambs were susceptible to helminth infection during lactation; lambs in both treatments had high fecal egg counts (FECs), with means >1000 eggs per gram, as early as 45days of age, when the daily grazing time per animal increased. Creep feeding reduced the FECs of suckling lambs >60days of age in infections dominated by Haemonchus contortus. Totals of 20 and 48 anthelmintic treatments were administered to the supplemented and unsupplemented animals, respectively. The effect of this variable, however, was significant (P<0.05) only after 60days, when nine and 28 treatments had been administered to the supplemented and unsupplemented lambs, respectively. The number of strongyloid larvae recovered from the paddock did not differ significantly (P >0.05) between the two treatments, indicating similar challenges by infective larvae to both groups. The supplementation of lambs by creep feeding can thus be a strategy for the sustainable control of helminth infection, because it reduces the dependence on anthelmintic treatment.
[Mh] Termos MeSH primário: Ração Animal
Criação de Animais Domésticos
Hemoncose/veterinária
Doenças dos Ovinos/parasitologia
[Mh] Termos MeSH secundário: Animais
Animais Lactentes
Suplementos Nutricionais
Feminino
Gastroenteropatias/parasitologia
Gastroenteropatias/prevenção & controle
Gastroenteropatias/veterinária
Hemoncose/prevenção & controle
Haemonchus
Masculino
Ovinos
Doenças dos Ovinos/prevenção & controle
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171031
[Lr] Data última revisão:
171031
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170513
[St] Status:MEDLINE


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[PMID]:28445594
[Au] Autor:Radloff J; Zakrzewski SS; Pieper R; Markov AG; Amasheh S
[Ad] Endereço:Institute of Veterinary Physiology, Freie Universität Berlin, Berlin, Germany.
[Ti] Título:Porcine milk induces a strengthening of barrier function in porcine jejunal epithelium in vitro.
[So] Source:Ann N Y Acad Sci;1397(1):110-118, 2017 Jun.
[Is] ISSN:1749-6632
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Milk contains a variety of components that have been shown to affect the expression and localization of epithelial tight junction proteins and therefore the intestinal barrier. Thus, we hypothesized that milk would have an effect on intestinal barrier properties, owing to effects on the tight junction in an intraspecies porcine intestinal in vitro model. Jejunal samples of piglets derived from different age groups were analyzed. Transepithelial electrical resistance was recorded employing the Ussing chamber technique. Porcine milk or predigested milk in buffer solution was added to the apical side, and effects were compared to untreated controls. Unidirectional paracellular flux measurements were performed using sodium fluorescein. Tight junction protein expression and localization were analyzed by immunoblotting and immunofluorescence microscopy. Incubation with milk or predigested milk led to an increase in transepithelial electrical resistance, while paracellular permeability for sodium fluorescein did not result in significant changes. Densitometric analysis of immunoblot signals did not show significant alterations in claudin expression, but a reduction of claudin signals in apicolateral membrane compartments in both approaches became apparent via immunohistology. The functional effect might reflect a physiological protective mechanism, when offspring exclusively rely on their mother's milk and are exposed to a plethora of potentially barrier-perturbing factors.
[Mh] Termos MeSH primário: Impedância Elétrica
Mucosa Intestinal/fisiologia
Jejuno/fisiologia
Leite/fisiologia
[Mh] Termos MeSH secundário: Fatores Etários
Animais
Animais Lactentes
Transporte Biológico/efeitos dos fármacos
Claudinas/metabolismo
Ácidos Graxos/farmacologia
Feminino
Immunoblotting
Técnicas In Vitro
Mucosa Intestinal/efeitos dos fármacos
Mucosa Intestinal/metabolismo
Jejuno/efeitos dos fármacos
Jejuno/metabolismo
Microscopia Confocal
Microscopia de Fluorescência
Leite/química
Permeabilidade/efeitos dos fármacos
Transdução de Sinais/efeitos dos fármacos
Suínos
Proteínas de Junções Íntimas/metabolismo
Fator de Crescimento Transformador beta1/farmacologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Claudins); 0 (Fatty Acids); 0 (Tight Junction Proteins); 0 (Transforming Growth Factor beta1)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170822
[Lr] Data última revisão:
170822
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170427
[St] Status:MEDLINE
[do] DOI:10.1111/nyas.13340


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[PMID]:28380616
[Au] Autor:Farmer C; Amezcua M; Bruckmaier R; Wellnitz O; Friendship R
[Ti] Título:Does duration of teat use in first parity affect milk yield and mammary gene expression in second parity?
[So] Source:J Anim Sci;95(2):681-687, 2017 Feb.
[Is] ISSN:1525-3163
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:It was recently shown that a teat that is not used in the first lactation will have a reduced development and milk yield in the second lactation. In the current study, the impact of imposing a suckling period of 2, 7, or 21 d during the first lactation on piglet performance, milk composition, endocrine status, and mammary gene expression of sows in their second lactation was studied. Pregnant Yorkshire gilts were divided into 3 groups according to lactation length: 1) 2-d lactation (2D; = 20), 2) 7-d lactation (7D; = 20), and 3) 21-d lactation (21D; = 21). After weaning, sows were bred and kept for a second parity. In both lactations, litters were standardized to 12 piglets with 12 functional teats and surplus teats were sealed. In the second lactation, piglets were weighed on d 2, 7, 14, 21 (weaning), 31, and 56 postpartum, and sow feed intake was recorded. On d 110 of gestation and on d 21 of lactation, mammary biopsies were performed on 10 sows per treatment to obtain parenchymal tissue samples for determination of mRNA abundance for , , , , , and genes. Milk samples and jugular blood samples were also obtained from sows on d 21 of lactation. Standard composition analyses (DM, fat, protein, and lactose) were done in milk. Concentrations of prolactin, IGF-1, glucose, and urea were measured in blood. There was a tendency for 21D sows to consume more feed than 2D or 7D sows during the first week of lactation ( < 0.10). There was no treatment effect on BW of piglets at any time until d 56 ( > 0.10). Concentrations of prolactin, IGF-1, urea, and glucose in sows on d 21 of lactation were not affected by treatment ( > 0.10). Dry matter, fat, protein, and lactose contents in milk were not altered by treatment ( > 0.10). On d 110 of gestation, gene expression was greater ( = 0.05) in 21D sows than in 7D sows. On d 21 of lactation, gene expression of was greater ( = 0.05) and that of tended to be lower ( < 0.10) in 7D sows than in 2D sows. The mRNA abundance of also tended to be lower ( < 0.10) in 2D sows than in 7D sows. Results indicate that increasing the duration of lactation from 2 d to 7 d or to 21 d in first-parity sows did not improve growth rate of their piglets in the subsequent lactation. This suggests that suckling of a teat for 2 d during the first lactation is sufficient to ensure optimal mammary development.
[Mh] Termos MeSH primário: Animais Lactentes/fisiologia
Regulação da Expressão Gênica/fisiologia
Lactação/fisiologia
Glândulas Mamárias Animais/fisiologia
Leite/química
Suínos/fisiologia
[Mh] Termos MeSH secundário: Animais
Feminino
Fator de Crescimento Insulin-Like I/genética
Fator de Crescimento Insulin-Like I/metabolismo
Paridade
Gravidez
Fatores de Tempo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
67763-96-6 (Insulin-Like Growth Factor I)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170718
[Lr] Data última revisão:
170718
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170406
[St] Status:MEDLINE
[do] DOI:10.2527/jas.2016.1119


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[PMID]:28355282
[Au] Autor:Massardier-Galatà L; Morinay J; Bailleul F; Wajnberg E; Guinet C; Coquillard P
[Ad] Endereço:Université Côte d'Azur, Nice, France.
[Ti] Título:Breeding success of a marine central place forager in the context of climate change: A modeling approach.
[So] Source:PLoS One;12(3):e0173797, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:In response to climate warming, a southward shift in productive frontal systems serving as the main foraging sites for many top predator species is likely to occur in Subantarctic areas. Central place foragers, such as seabirds and pinnipeds, are thus likely to cope with an increase in the distance between foraging locations and their land-based breeding colonies. Understanding how central place foragers should modify their foraging behavior in response to changes in prey accessibility appears crucial. A spatially explicit individual-based simulation model (Marine Central Place Forager Simulator (MarCPFS)), including bio-energetic components, was built to evaluate effects of possible changes in prey resources accessibility on individual performances and breeding success. The study was calibrated on a particular example: the Antarctic fur seal (Arctocephalus gazella), which alternates between oceanic areas in which females feed and the land-based colony in which they suckle their young over a 120 days rearing period. Our model shows the importance of the distance covered to feed and prey aggregation which appeared to be key factors to which animals are highly sensitive. Memorization and learning abilities also appear to be essential breeding success traits. Females were found to be most successful for intermediate levels of prey aggregation and short distance to the resource, resulting in optimal female body length. Increased distance to resources due to climate warming should hinder pups' growth and survival while female body length should increase.
[Mh] Termos MeSH primário: Comportamento Alimentar/fisiologia
Otárias/fisiologia
Modelos Estatísticos
Comportamento Predatório/fisiologia
Reprodução/fisiologia
[Mh] Termos MeSH secundário: Animais
Animais Recém-Nascidos
Animais Lactentes/fisiologia
Regiões Antárticas
Mudança Climática
Ecossistema
Feminino
Oceanos e Mares
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170829
[Lr] Data última revisão:
170829
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170330
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0173797


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[PMID]:28353243
[Au] Autor:Ma D; Ozanne SE; Guest PC
[Ad] Endereço:Department of neurosciences, University of Cambridge, Clifford Allbutt building, Hills road, Cambridge, CB2 0AH, UK.
[Ti] Título:A Protocol for Producing the Maternal Low-Protein Rat Model: A Tool for Preclinical Proteomic Studies.
[So] Source:Adv Exp Med Biol;974:251-255, 2017.
[Is] ISSN:0065-2598
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Epidemiological studies have shown that periods of poor nutrition during pregnancy can lead to an increased risk of metabolic and psychiatric disorders in the offspring. In addition, some individuals with disorders such as schizophrenia show signs of impaired insulin signalling. These findings indicate that there may be a link between metabolism and neuronal function and they also provide supporting evidence for neurodevelopmental origins of mental illness. This chapter gives a detailed protocol for generation of the maternal low-protein (LP) rat model, which leads to metabolic disturbances in the offspring. This model has been used in proteomic studies of several disorders including schizophrenia.
[Mh] Termos MeSH primário: Dieta com Restrição de Proteínas/efeitos adversos
Modelos Animais de Doenças
Complicações na Gravidez/fisiopatologia
Efeitos Tardios da Exposição Pré-Natal
Desnutrição Proteico-Calórica/fisiopatologia
Esquizofrenia/etiologia
[Mh] Termos MeSH secundário: Animais
Animais Lactentes
Feminino
Lactação
Gravidez
Complicações na Gravidez/etiologia
Desnutrição Proteico-Calórica/etiologia
Ratos
Ratos Wistar
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170928
[Lr] Data última revisão:
170928
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170330
[St] Status:MEDLINE
[do] DOI:10.1007/978-3-319-52479-5_22


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[PMID]:28319268
[Au] Autor:Matsumoto T
[Ad] Endereço:Graduate School of Science, Kyoto University, Kitashirakawa-Oiwake-Cho, Sakyo, Kyoto, 606-8502, Japan.
[Ti] Título:Developmental changes in feeding behaviors of infant chimpanzees at Mahale, Tanzania: Implications for nutritional independence long before cessation of nipple contact.
[So] Source:Am J Phys Anthropol;163(2):356-366, 2017 Jun.
[Is] ISSN:1096-8644
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVES: Weaning of chimpanzees is considered to occur at 4-5-years-old with complete cessation of nipple contact and timing of reconception calculated by inter-birth interval minus gestation length. This is also the basis of "early weaning" in humans (i.e., approximately 2.5-years-old). However, recent studies of the survival of orphans and the first molar (M1) eruption in wild chimpanzees have predicted that infants move toward nutritional independence at 3-years-old. Therefore, this study aimed to investigate ontogeny of feeding behavior at around 3-years-old in wild infant chimpanzees. MATERIALS AND METHODS: I studied 19 infants aged 1-60 months in the M group in Mahale Mountains National Park, Tanzania. The total observation time was 518 h, 25 min. RESULTS: At around 3-years-old, infant chimpanzees spent more total feeding time, and time feeding on leaves, and food physically difficult to process without food transfer from other individuals. These results suggest that infant chimpanzees significantly reduced their dependence on milk for nutrition at around 3-years-old, that is, before cessation of nipple contact. DISCUSSION: This study suggests that M1 eruption in wild Eastern Chimpanzees is an index of the period when infants move toward nutritional independence with a key dietary transition. This is the first study to provide behavioral evidence of the large temporal gap between nutritional independence of infants and reconception of mothers in great apes, and clarify the unique feature of human life history whereby mothers can reconceive before an infant reaches nutritional independence.
[Mh] Termos MeSH primário: Animais Lactentes/crescimento & desenvolvimento
Comportamento Alimentar/fisiologia
Pan troglodytes/crescimento & desenvolvimento
Desmame
[Mh] Termos MeSH secundário: Animais
Animais Lactentes/fisiologia
Antropologia Física
Feminino
Masculino
Modelos Biológicos
Mamilos/fisiologia
Pan troglodytes/fisiologia
Tanzânia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170626
[Lr] Data última revisão:
170626
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170321
[St] Status:MEDLINE
[do] DOI:10.1002/ajpa.23212


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[PMID]:28240159
[Au] Autor:He L; Zang J; Liu P; Fan P; Song P; Chen J; Ma Y; Ding W; Ma X
[Ad] Endereço:State Key Laboratory of Animal Nutrition, Ministry of Agriculture Feed Industry Centre, China Agricultural University, Beijing 100193. China.
[Ti] Título:Supplementation of Milky Flavors Improves the Reproductive Performance and Gut Function Using Sow Model.
[So] Source:Protein Pept Lett;24(5):449-455, 2017.
[Is] ISSN:1875-5305
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:This study was conducted to evaluate the effect of flavors on reproductive performance of sows and we also studied its effect on gut barrier function. Forty-eight Landrace × Yarkshire sows were randomly allotted and fed a basal diet added 0%, 0.05% or 0.10% flavor feed, respectively from parturition to day 28 of weaning. The results showed that supplementation of 0.05% or 0.10% flavors increased average daily feed intake (ADFI) of sows and average daily gain (ADG) of piglets, decreased the weight losses of sows, increased the survival ratio of weaning piglets (P < 0.05), especially shorten the post-weaning estrus interval significantly (P < 0.05). Supplementation of flavor additives tend to reduce the weight losses of sows and raise the survival ratio of piglet weaned (P > 0.05). Moreover, addition of flavors in diets reduced the intestinal permeability and enhanced digestibility of dry matter, crude protein, and energy (P < 0.05). Flavors supplementation significantly increased the level of gonadotropin releasing hormne (GnRH) of serum in sows after weaning. In conclusion, the results suggested that supplementation of dietary flavors could improve digestibility of nutrients and the reproductive performance of sows as well as the gut barrier function.
[Mh] Termos MeSH primário: Ração Animal
Suplementos Nutricionais
Lactação/fisiologia
Modelos Biológicos
Reprodução/fisiologia
[Mh] Termos MeSH secundário: Animais
Animais Lactentes
Feminino
Absorção Gastrointestinal/fisiologia
Hormônio Liberador de Gonadotropina/sangue
Sus scrofa
Suínos
Ganho de Peso
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
33515-09-2 (Gonadotropin-Releasing Hormone)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171002
[Lr] Data última revisão:
171002
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170228
[St] Status:MEDLINE
[do] DOI:10.2174/0929866524666170223144728


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[PMID]:28183150
[Au] Autor:Kong Z; Jie H; Zhou C; Yang L; Tan Z; Yang W
[Ad] Endereço:Key Laboratory of Agro-ecological Processes in Subtropical Region, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha, China.
[Ti] Título:Effects of dietary supplementation of Acanthopanax senticosus on gastrointestinal tract development in calves.
[So] Source:Anim Sci J;88(9):1321-1326, 2017 Sep.
[Is] ISSN:1740-0929
[Cp] País de publicação:Australia
[La] Idioma:eng
[Ab] Resumo:Twenty-four newborn Holstein dairy male calves (with initial body weight of 38 ± 3.0 kg) were used in a randomized block design experiment to determine effects of dietary supplementation of Acanthopanax senticosus (AS) on gastrointestinal tract development. Calves were fed milk (10%/body weight) three times at 06.00, 12.00 and 18.00 hours daily with one to four treatments during the experimental periods (4 to 28 days): no supplementation of AS (control group, CG); 1.0 g/L•time of micro-powder AS (MP); 1.0 g/L•time of superfine powder AS (SP); or 1.0 g/L•time of coarse powder AS (CP). On days 7, 14, 21 and 28, 20 mL blood samples were collected at 06.00 hours before the morning feeding. At the end of the trial (28 days), all calves were euthanized, and tissue samples were taken and placed in 4% buffered formaldehyde for analyses. In the rumen of MP treatment, compared with the CG treatment, wall thickness and papillae diameter was both significantly lower (P<0.05), while crypt depth was significantly greater (P<0.05). In the duodenum, villi diameter of AS supplemented treatments was significantly lower than that of CG treatment (P<0.05). Results indicate that calves during sucking period supplemented with AS as MP style could promote gastrointestinal development.
[Mh] Termos MeSH primário: Ração Animal
Bovinos/crescimento & desenvolvimento
Dieta/veterinária
Suplementos Nutricionais
Eleutherococcus
Trato Gastrointestinal/crescimento & desenvolvimento
[Mh] Termos MeSH secundário: Animais
Animais Recém-Nascidos
Animais Lactentes
Masculino
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171005
[Lr] Data última revisão:
171005
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170210
[St] Status:MEDLINE
[do] DOI:10.1111/asj.12764



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