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  1 / 2267 MEDLINE  
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[PMID]:28691813
[Au] Autor:Kamalakkannan V; Salim AA; Capon RJ
[Ad] Endereço:Division of Chemistry and Structural Biology, Institute for Molecular Bioscience, The University of Queensland , St Lucia, Queensland 4072, Australia.
[Ti] Título:Microbiome-Mediated Biotransformation of Cane Toad Bufagenins.
[So] Source:J Nat Prod;80(7):2012-2017, 2017 Jul 28.
[Is] ISSN:1520-6025
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Cane toads are an invasive pest species in which all life stages employ cardiotoxic bufagenins as a chemical defense against predators. Curiously, the bufagenin profiles of eggs and tadpoles are more complex than those of parotoid secretion, the principle mechanism of toxin delivery in adult toads. In an effort to understand this complexity, we determined that selected strains of adult toad parotoid-gland-associated Gram-positive bacteria, Bacillus spp., were capable of biotransforming secreted bufagenins, marinobufagenin (1), telocinobufagenin (2), bufalin (3), and resibufagenin (4), to hydroxylated scaffolds commonly encountered in cane toad eggs and tadpoles. Scaled-up cultivation, preparative chromatography, and detailed spectroscopic analysis identified Bacillus sp. CMB-TD29 biotransformation products of 1, as 11α-hydroxymarinobufagenin (6), 12ß-hydroxymarinobufagenin (7), and 17α-hydroxymarinobufagenin (8). Comparative bufagenin profiles across the cane toad life cycle suggest that bacterial biotransformation mediates the oxidative adaptation of adult toad bufagenins to hydroxylated bufagenins encountered in eggs and tadpoles. We speculate that knowledge of a relationship between the cane toad microbiome and bufagenin chemical defenses could inspire the development of a natural, nontoxic, environmentally sustainable bacterial biocontrol for this toxic invasive species.
[Mh] Termos MeSH primário: Bufanolídeos/metabolismo
Bufo marinus
Espécies Introduzidas
Microbiota/fisiologia
Toxinas Biológicas/fisiologia
[Mh] Termos MeSH secundário: Animais
Bacillus/metabolismo
Biotransformação
Bufanolídeos/química
Larva/fisiologia
Estrutura Molecular
Ressonância Magnética Nuclear Biomolecular
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Bufanolides); 0 (Toxins, Biological); 3KBT25GV2B (marinobufagenin); U549S98QLW (bufalin)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170711
[St] Status:MEDLINE
[do] DOI:10.1021/acs.jnatprod.7b00134


  2 / 2267 MEDLINE  
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[PMID]:28637657
[Au] Autor:Ge D; Lavidis N
[Ad] Endereço:School of Biomedical Sciences, The University of Queensland, St. Lucia, Australia.
[Ti] Título:Seasonal factors influence quantal transmitter release and calcium dependence at amphibian neuromuscular junctions.
[So] Source:Am J Physiol Regul Integr Comp Physiol;313(3):R202-R210, 2017 Sep 01.
[Is] ISSN:1522-1490
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Amphibian neuromuscular junctions (NMJs) are composed of hundreds of neurotransmitter release sites that exhibit nonuniform transmitter release probabilities and demonstrated seasonal modulation. We examined whether recruitment of release sites is variable when the extracellular calcium concentration ([Ca ] ) is increased in the wet and dry seasons. The amount of transmitter released from the entire nerve terminal increases by approximately the fourth power as [Ca ] is increased. Toad ( ) NMJs were visualized using 3,3'-diethyloxardicarbocyanine iodide [DiOC (5)] fluorescence, and focal loose patch extracellular recordings were used to record the end-plate currents (EPCs) from small groups of release sites. Quantal content ( ), average probability of quantal release ( ), and the number of active release sites ( ) were determined for different [Ca ] Our results indicated that the recruitment of quantal release sites with increasing [Ca ] differs spatially (between different groups of release sites) and also temporally (in different seasons). These differences were reflected by the nonuniform alterations in and Most release site groups demonstrated an increase in both and when [Ca ] increased. In ~30% of release site groups examined, decreased while increased only during the active period (wet season). Although the dry season induced parallel right shift in the quantal release versus extracellular calcium concentration when compared with the wet season, the dependence of quantal content on [Ca ] was not changed. These results demonstrate the flexibility, reserve, and adaptive capacity of neuromuscular junctions in maintaining appropriate levels of neurotransmission.
[Mh] Termos MeSH primário: Bufo marinus/fisiologia
Sinalização do Cálcio/fisiologia
Cálcio/metabolismo
Junção Neuromuscular/fisiologia
Neurotransmissores/metabolismo
Estações do Ano
Transmissão Sináptica/fisiologia
[Mh] Termos MeSH secundário: Animais
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Neurotransmitter Agents); SY7Q814VUP (Calcium)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:171005
[Lr] Data última revisão:
171005
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170623
[St] Status:MEDLINE
[do] DOI:10.1152/ajpregu.00070.2017


  3 / 2267 MEDLINE  
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[PMID]:28623798
[Au] Autor:Svartz G; Papa M; Gosatti M; Jordán M; Soldati A; Samter P; Guraya MM; Pérez Coll C; Perez Catán S
[Ad] Endereço:Instituto de Investigación e Ingeniería Ambiental and Escuela de Ciencia y Tecnología (UNSAM), Av. 25 de Mayo y Francia (C1650), San Martín, Buenos Aires, Argentina; CONICET, Argentina.
[Ti] Título:Monitoring the ecotoxicity of γ-Al O and Ni/γ-Al O nanomaterials by means of a battery of bioassays.
[So] Source:Ecotoxicol Environ Saf;144:200-207, 2017 Oct.
[Is] ISSN:1090-2414
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:The increasing application of nanoparticles (NPs) to a variety of new technologies has become a matter of concern due to the potential toxicity of these materials. Many questions about the fate of NPs in the environment and the subsequent impact on ecosystems need to be answered. The aim of this work was to evaluate the ecotoxicity of two alumina-based nanoceramics, γ-Al2O3 (NC) and Ni/ γ-Al2O3 (NiNC) by means of three different standardized tests: Biochemical Oxygen Demand (BOD5), bioassay with luminescent bacteria (Vibrio fischeri; Microtox), and bioassay on amphibian larvae (Rhinella arenarum) (AMPHITOX). BOD5 values of a very biodegradable mixture (glucose/glutamic acid) decreased with the addition of NiNC(43.8%) and NC (31.6%) with respect to control samples (52.9%). Microtox test results indicated that NiNC presents higher toxicity than NC, with EC50s values of 16.1% and 29.9% respectively; a reduced toxicity was observed, however, in presence of organic matter, thus obtaining EC50s of 37.8% and 19.4%. The results of AMPHITOX test showed a significant increase in the toxicity of both substances over time, the NiNC toxicity being greater than that of NC. The values of 96h-LC50 and 504h-LC50 determined for NiNC were 1.58 and 0.83mg/L, respectively, and 14.5 and 10.5mg/L for NC samples. Amphibian larvae exhibited collapsed cavities, edema, axial flexures, and behavioral alterations as hyperkinesia and reduced movements. These results evidence the vulnerability of wildlife to xenobiotics and the need to develop specific standardized ecotoxicity tests in order to help environmental sustainability and natural species conservation.
[Mh] Termos MeSH primário: Aliivibrio fischeri/efeitos dos fármacos
Óxido de Alumínio/toxicidade
Monitoramento Ambiental/métodos
Larva/efeitos dos fármacos
Nanopartículas/toxicidade
Níquel/toxicidade
[Mh] Termos MeSH secundário: Animais
Bioensaio
Análise da Demanda Biológica de Oxigênio
Bufo marinus
Ecotoxicologia
Propriedades de Superfície
Xenobióticos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Xenobiotics); 7OV03QG267 (Nickel); LMI26O6933 (Aluminum Oxide)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171110
[Lr] Data última revisão:
171110
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170618
[St] Status:MEDLINE


  4 / 2267 MEDLINE  
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[PMID]:28432445
[Au] Autor:Pettit L; Greenlees M; Shine R
[Ad] Endereço:School of Life and Environmental Sciences, University of Sydney, Sydney, NSW, 2006, Australia.
[Ti] Título:The impact of transportation and translocation on dispersal behaviour in the invasive cane toad.
[So] Source:Oecologia;184(2):411-422, 2017 Jun.
[Is] ISSN:1432-1939
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:Biological invasions transport organisms to novel environments; but how does the translocation process influence movement patterns of the invader? Plausibly, the stress of encountering a novel environment, or of the transport process, might induce rapid dispersal from the release site-potentially enhancing (or reducing) invader success and spread. We investigated the effect of transportation and release to novel environments on dispersal-relevant traits of one of the world's most notorious invaders, the cane toad (Rhinella marina). We collected toads in northern New South Wales from heath and woodland habitats, manipulated the level of transport stress and either returned toads to their exact collection point (residents) or reciprocally translocated them to a novel site. Both translocation and the level of transport stress drastically altered toad dispersal rates for at least 5 days post-release. Translocated toads (depending on their level of transport stress and release habitat) moved on average two to five times further per day (mean range 67-148 m) than did residents (mean range 22-34 m). Translocated toads also moved on more days, and moved further from their release point than did resident toads, but did not move in straighter lines. A higher level of transport stress (simulating long-distance translocation) had no significant effect on movements of resident toads but amplified the dispersal of translocated toads only when released into woodland habitat. These behavioural shifts induced by translocation and transportation may affect an invader's ability to colonise novel sites, and need to be incorporated into plans for invader control.
[Mh] Termos MeSH primário: Bufo marinus
Espécies Introduzidas
Transportes
[Mh] Termos MeSH secundário: Animais
Austrália
Ecossistema
Meio Ambiente
New South Wales
Dinâmica Populacional
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171012
[Lr] Data última revisão:
171012
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170423
[St] Status:MEDLINE
[do] DOI:10.1007/s00442-017-3871-y


  5 / 2267 MEDLINE  
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[PMID]:28131913
[Au] Autor:Schmeda-Hirschmann G; Gomez CV; Rojas de Arias A; Burgos-Edwards A; Alfonso J; Rolon M; Brusquetti F; Netto F; Urra FA; Cárdenas C
[Ad] Endereço:Laboratorio de Química de Productos Naturales, Instituto de Química de Recursos Naturales, Universidad de Talca, Casilla 747, 3460000 Talca, Chile. Electronic address: schmeda@utalca.cl.
[Ti] Título:The Paraguayan Rhinella toad venom: Implications in the traditional medicine and proliferation of breast cancer cells.
[So] Source:J Ethnopharmacol;199:106-118, 2017 Mar 06.
[Is] ISSN:1872-7573
[Cp] País de publicação:Ireland
[La] Idioma:eng
[Ab] Resumo:ETHNOPHARMACOLOGICAL RELEVANCE: Toads belonging to genus Rhinella are used in Paraguayan traditional medicine to treat cancer and skin infections. AIM OF THE STUDY: The objective of the study was to determine the composition of venoms obtained from three different Paraguayan Rhinella species, to establish the constituents of a preparation sold in the capital city of Paraguay to treat cancer as containing the toad as ingredient, to establish the effect of the most active Rhinella schneideri venom on the cell cycle using human breast cancer cells and to assess the antiprotozoal activity of the venoms. METHODS: The venom obtained from the toads parotid glands was analyzed by HPLC-MS-MS. The preparation sold in the capital city of Paraguay to treat cancer that is advertised as made using the toad was analyzed by HPLC-MS-MS. The effect of the R. schneideri venom and the preparation was investigated on human breast cancer cells. The antiprotozoal activity was evaluated on Leishmania braziliensis, L. infantum and murine macrophages. RESULTS: From the venoms of R. ornata, R. schneideri and R. scitula, some 40 compounds were identified by spectroscopic and spectrometric means. Several minor constituents are reported for the first time. The preparation sold as made from the toad did not contained bufadienolides or compounds that can be associated with the toad but plant compounds, mainly phenolics and flavonoids. The venom showed activity on human breast cancer cells and modified the cell cycle proliferation. The antiprotozoal effect was higher for the R. schneideri venom and can be related to the composition and relative ratio of constituents compared with R. ornata and R. scitula. CONCLUSIONS: The preparation sold in the capital city of Paraguay as containing the toad venom, used popularly to treat cancer did not contain the toad venom constituents. Consistent with this, this preparation was inactive on proliferation of human breast cancer cells. In contrast, the toad venoms of Rhinella species altered the cell cycle progression, affecting the proliferation of malignant cells. The findings suggest that care should be taken with the providers of the preparation and that the crude drug present a strong activity towards human breast cancer cell lines. The antiprotozoal effect of the R. schneideri venom was moderate while the venom of R. ornata was devoid of activity and that of R. scitula was active at very high concentration.
[Mh] Termos MeSH primário: Venenos de Anfíbios/isolamento & purificação
Venenos de Anfíbios/farmacologia
Neoplasias da Mama/patologia
Proliferação Celular/efeitos dos fármacos
Medicina Tradicional/métodos
[Mh] Termos MeSH secundário: Venenos de Anfíbios/química
Animais
Bufo marinus
Linhagem Celular Tumoral
Proliferação Celular/fisiologia
Células Cultivadas
Feminino
Seres Humanos
Macrófagos/efeitos dos fármacos
Macrófagos/fisiologia
Camundongos
Paraguai
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Amphibian Venoms)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170714
[Lr] Data última revisão:
170714
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170130
[St] Status:MEDLINE


  6 / 2267 MEDLINE  
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[PMID]:28039530
[Au] Autor:Flores-Ramírez R; Espinosa-Reyes G; Cilia-López VG; González-Mille DJ; Rodríguez-Aguilar M; Díaz de León-Martínez L; Díaz-Barriga F
[Ad] Endereço:Coordinación para la Innovación y Aplicación de la Ciencia y la Tecnología (CIACYT), Avenida Sierra Leona No. 550, Colonia Lomas Segunda Sección, CP 78210, San Luis Potosí, SLP, Mexico. rfloresra@conacyt.mx.
[Ti] Título:Application of Focused Ultrasound-Assisted Extraction for the Quantification of Persistent Organic Pollutions in Liver Tissue of Giant Toad (Rhinella marina).
[So] Source:Bull Environ Contam Toxicol;98(2):204-211, 2017 Feb.
[Is] ISSN:1432-0800
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:A simple and rapid focused ultrasound extraction method was developed for the determination of Persistent Organic Pollutants (POPs) in liver tissue obtained of giant toad (Rhinella marina) using a gas chromatography coupled to a mass detector with electron impact ionization. The performed method for POPs, was validated in fortified matrix, showing linearity from the LOQ up to 100 ng/mL; LODs and LOQs for each compound were between 1.7 and 4.8 and 3.5-7.5 ng/mL, respectively. Recovery rates were among 79%-116% for POPs determined. Finally, the method was applied in liver samples of giant toads found in a malarial area in Mexico. The sensitivity of the proposed method was good enough to ensure reliable determination of target analytes at concentration levels commonly found in this kind of samples.
[Mh] Termos MeSH primário: Bufo marinus/metabolismo
Poluentes Ambientais/metabolismo
[Mh] Termos MeSH secundário: Animais
Poluição Ambiental
Cromatografia Gasosa-Espectrometria de Massas
Limite de Detecção
Fígado/metabolismo
México
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Environmental Pollutants)
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170101
[St] Status:MEDLINE
[do] DOI:10.1007/s00128-016-2009-y


  7 / 2267 MEDLINE  
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[PMID]:27579495
[Au] Autor:Ward-Fear G; Thomas J; Webb JK; Pearson DJ; Shine R
[Ad] Endereço:School of Life and Environmental Sciences, University of Sydney, Sydney, New South Wales, Australia.
[Ti] Título:Eliciting conditioned taste aversion in lizards: Live toxic prey are more effective than scent and taste cues alone.
[So] Source:Integr Zool;12(2):112-120, 2017 Mar.
[Is] ISSN:1749-4877
[Cp] País de publicação:Australia
[La] Idioma:eng
[Ab] Resumo:Conditioned taste aversion (CTA) is an adaptive learning mechanism whereby a consumer associates the taste of a certain food with symptoms caused by a toxic substance, and thereafter avoids eating that type of food. Recently, wildlife researchers have employed CTA to discourage native fauna from ingesting toxic cane toads (Rhinella marina), a species that is invading tropical Australia. In this paper, we compare the results of 2 sets of CTA trials on large varanid lizards ("goannas," Varanus panoptes). One set of trials (described in this paper) exposed recently-captured lizards to sausages made from cane toad flesh, laced with a nausea-inducing chemical (lithium chloride) to reinforce the aversion response. The other trials (in a recently-published paper, reviewed herein) exposed free-ranging lizards to live juvenile cane toads. The effectiveness of the training was judged by how long a lizard survived in the wild before it was killed (fatally poisoned) by a cane toad. Both stimuli elicited rapid aversion to live toads, but the CTA response did not enhance survival rates of the sausage-trained goannas after they were released into the wild. In contrast, the goannas exposed to live juvenile toads exhibited higher long-term survival rates than did untrained conspecifics. Our results suggest that although it is relatively easy to elicit short-term aversion to toad cues in goannas, a biologically realistic stimulus (live toads, encountered by free-ranging predators) is most effective at buffering these reptiles from the impact of invasive toxic prey.
[Mh] Termos MeSH primário: Aprendizagem da Esquiva
Bufo marinus
Lagartos/fisiologia
Odorantes
Paladar
Toxinas Biológicas/toxicidade
[Mh] Termos MeSH secundário: Animais
Sinais (Psicologia)
Espécies Introduzidas
Cloreto de Lítio
Comportamento Predatório
Austrália Ocidental
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Toxins, Biological); G4962QA067 (Lithium Chloride)
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170406
[Lr] Data última revisão:
170406
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160901
[St] Status:MEDLINE
[do] DOI:10.1111/1749-4877.12226


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[PMID]:27468033
[Au] Autor:Díaz-Páez H; Cortez E; de la Fuente CS; Moreno Salas L
[Ti] Título:BODY DISTRIBUTION OF HANNEMANIA SP. (ACARI: LEEUWENHOEKIIDAE) IN RHINELLA SPINULOSA, PLEURODEMA BUFONINA, AND PLEURODEMA THAUL FROM CHILE.
[So] Source:J Zoo Wildl Med;47(2):594-600, 2016 Jun.
[Is] ISSN:1042-7260
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Hannemania larvae are parasites of amphibians in North and South America. In Chile, only one species of Hannemania has been reported from Batrachyla taeniata (banded wood frog). The objective of the study was to determine the abundance and body distribution of Hannemania among three amphibians from Antuco (Biobío Region, Chile): Pleurodema thaul (13 adults; Chile four-eyed frog), Pleurodema bufonina (5 adults; large four-eyed frog), and Rhinella spinulosa (15 adults and 16 juveniles; warty toad). Amphibians (82.75 %; n = 49) were infested with Hannemania. The infestation rate in R. spinulosa juveniles was lower than in adults (68 versus 100%, respectively; mean larval intensity: juvenile = 3.2 ± 2.5 and adult = 17.3 ± 16.3). Mean intensity of larval infestation in P. bufonina (63.2 ± 47.9) was higher than in the other two species of amphibians (R. spinulosa adult: 17.3 ± 16.3; R. spinulosa juvenile: 3.2 ± 2.5; P. thaul: 11.62 ± 7.8). There was no significant association between body size and mean intensity of infestation. The inguinal region, ventrum, and dorsal forearm region were the most parasitized. These body zones would be in direct contact with the substrate making the infestation easier for the larvae. This study represents the first record of Hannemania sp. in P. bufonina, R. spinulosa, and P. thaul in Chile.
[Mh] Termos MeSH primário: Anuros/parasitologia
Bufo marinus/parasitologia
Infestações por Ácaros/veterinária
Ácaros/classificação
[Mh] Termos MeSH secundário: Animais
Chile/epidemiologia
Infestações por Ácaros/epidemiologia
Infestações por Ácaros/parasitologia
Especificidade da Espécie
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1609
[Cu] Atualização por classe:160729
[Lr] Data última revisão:
160729
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160729
[St] Status:MEDLINE
[do] DOI:10.1638/2015-0047.1


  9 / 2267 MEDLINE  
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[PMID]:27445278
[Au] Autor:Dohn NB; Fago A; Overgaard J; Madsen PT; Malte H
[Ad] Endereço:Danish School of Education, Aarhus University, Aarhus, Denmark; and dohn@edu.au.dk.
[Ti] Título:Students' motivation toward laboratory work in physiology teaching.
[So] Source:Adv Physiol Educ;40(3):313-8, 2016 Sep.
[Is] ISSN:1522-1229
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The laboratory has been given a central role in physiology education, and teachers report that it is motivating for students to undertake experimental work on live animals or measuring physiological responses on the students themselves. Since motivation is a critical variable for academic learning and achievement, then we must concern ourselves with questions that examine how students engage in laboratory work and persist at such activities. The purpose of the present study was to investigate how laboratory work influences student motivation in physiology. We administered the Lab Motivation Scale to assess our students' levels of interest, willingness to engage (effort), and confidence in understanding (self-efficacy). We also asked students about the role of laboratory work for their own learning and their experience in the physiology laboratory. Our results documented high levels of interest, effort, and self-efficacy among the students. Correlation analyses were performed on the three motivation scales and exam results, yet a significant correlation was only found between self-efficacy in laboratory work and academic performance at the final exam. However, almost all students reported that laboratory work was very important for learning difficult concepts and physiological processes (e.g., action potential), as the hands-on experiences gave a more concrete idea of the learning content and made the content easier to remember. These results have implications for classroom practice as biology students find laboratory exercises highly motivating, despite their different personal interests and subject preferences. This highlights the importance of not replacing laboratory work by other nonpractical approaches, for example, video demonstrations or computer simulations.
[Mh] Termos MeSH primário: Ciência de Laboratório Médico/educação
Motivação
Fisiologia/educação
Autoeficácia
Estudantes de Ciências da Saúde/psicologia
Ensino/psicologia
[Mh] Termos MeSH secundário: Animais
Braquiúros
Bufo marinus
Feminino
Cobaias
Seres Humanos
Masculino
Oncorhynchus mykiss
Inquéritos e Questionários
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1701
[Cu] Atualização por classe:170120
[Lr] Data última revisão:
170120
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160723
[St] Status:MEDLINE
[do] DOI:10.1152/advan.00029.2016


  10 / 2267 MEDLINE  
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[PMID]:27394759
[Au] Autor:Acevedo AA; Lampo M; Cipriani R
[Ad] Endereço:Centro de Ecología, Instituto Venezolano de Investigaciones Científicas, Apartado 21827, Caracas, 1020-A, Venezuela. Grupo de Investigación en Ecología y Biogeografía (GIEB), Facultad de Ciencias; Email: mlampo@gmail.com.
[Ti] Título:The cane or marine toad, Rhinella marina (Anura, Bufonidae): two genetically and morphologically distinct species.
[So] Source:Zootaxa;4103(6):574-86, 2016 Apr 18.
[Is] ISSN:1175-5334
[Cp] País de publicação:New Zealand
[La] Idioma:eng
[Ab] Resumo:Rhinella marina is a Neotropical toad that has been introduced widely worldwide. Its toxic effects to frog-eating predators threaten the native and domestic fauna of some regions where it has been introduced. Despite previous studies suggesting two genetically distinct cryptic species within R. marina, one east and one west of the Andes, its taxonomic status remained unresolved due to the absence of morphological complementary evidence. For the first time, data from two mitochondrial genes (ND3 and CR) and 23 morphometric landmarks are combined to evaluate the taxonomic status of this species. Our results support the hypothesis of two separate evolutionary lineages within R. marina and demonstrate that these lineages have significantly diverged in skull shape. We identified two distinct morphotypes, one eastern and one Andean western, with no overlapping morphospaces. The geographic pattern of genetic variation was consistent with a stable structured population with no evidence of recent demographic or geographic expansions. The concordance between the observed geographic patterns in morphometric and genic traits calls for the recognition of two species under R. marina name.
[Mh] Termos MeSH primário: Bufo marinus/anatomia & histologia
Bufo marinus/genética
[Mh] Termos MeSH secundário: Distribuição Animal
Estruturas Animais/anatomia & histologia
Estruturas Animais/crescimento & desenvolvimento
Animais
Tamanho Corporal
Bufo marinus/classificação
Bufo marinus/crescimento & desenvolvimento
Feminino
Masculino
Tamanho do Órgão
Filogenia
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170303
[Lr] Data última revisão:
170303
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160711
[St] Status:MEDLINE
[do] DOI:10.11646/zootaxa.4103.6.7



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