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Pesquisa : B01.050.150.900.090.608.700.540 [Categoria DeCS]
Referências encontradas : 459 [refinar]
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[PMID]:28264286
[Au] Autor:Escoriza D; Hassine JB
[Ad] Endereço:GRECO, Institute of Aquatic Ecology, Faculty of Sciences, University of Girona, Campus Montilivi, 17071 Girona, Spain. daniel_escoriza@hotmail.com.
[Ti] Título:Comparative larval morphology in three species of Pleurodeles (Urodela: Salamandridae).
[So] Source:Zootaxa;4237(3):zootaxa.4237.3.11, 2017 Mar 01.
[Is] ISSN:1175-5334
[Cp] País de publicação:New Zealand
[La] Idioma:eng
[Ab] Resumo:The Ribbed newts (genus Pleurodeles) are endemic to the Iberian Peninsula and northwest Africa (Raffaëlli 2013), and comprise three species: Pleurodeles nebulosus (Guichenot 1850), Pleurodeles poireti (Gervais 1836) and Pleurodeles waltl Michahelles 1830. Pleurodeles nebulosus is found in northern Algeria and Tunisia with an average size of 18 cm, while P. poireti is endemic to the Edough Massif, in northeastern Algeria and is the smallest species, with 12.9 cm in total length (Escoriza et al. 2016; Carranza & Wade 2004). Pleurodeles waltl appears on the Iberian Peninsula and Morocco (García-París et al. 2004). The eastern and western populations of P. waltl although they are not differentiated taxonomically show high levels of genetic divergence (estimated to have occurred 2.0-3.2 Ma; Carranza & Arnold 2003). The individuals of P. waltl attain large sizes (30 cm of total length) and have 8-10 cutaneous glands on both sides (Pasteur 1958), which are absent in other species of the genus.
[Mh] Termos MeSH primário: Pleurodeles
[Mh] Termos MeSH secundário: Argélia
Animais
Larva
Marrocos
Paris
Tunísia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170810
[Lr] Data última revisão:
170810
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170308
[St] Status:MEDLINE
[do] DOI:10.11646/zootaxa.4237.3.11


  2 / 459 MEDLINE  
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[PMID]:28145573
[Au] Autor:Cubo J; Hui M; Clarac F; Quilhac A
[Ad] Endereço:Sorbonne Universités UPMC Univ Paris 6, CNRS, Institut des Sciences de la Terre de Paris (ISTeP), 4 place Jussieu - BC 19, Paris, 75005, France.
[Ti] Título:Static osteogenesis does not precede dynamic osteogenesis in periosteal ossification of Pleurodeles (Caudata, Amphibia) and Pogona (Squamata, Lepidosauria).
[So] Source:J Morphol;278(5):621-628, 2017 May.
[Is] ISSN:1097-4687
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Two successive mechanisms have been described in perichondral ossification: (1) in static osteogenesis, mesenchymal cells differentiate into stationary osteoblasts oriented randomly, which differentiate into osteocytes in the same site; (2) in dynamic osteogenesis, mesenchymal cells differentiate into osteoblasts that are all oriented in the same direction and move back as they secrete collagen fibers. This study is aimed at testing the hypothesis that the ontogenetic sequence static then dynamic osteogenesis observed in the chicken and in the rabbit is homologous and was acquired by the last common ancestor of amniotes or at a more inclusive node. For this we analyze the developmental patterns of Pleurodeles (Caudata, Amphibia) and those of the lizard Pogona (Squamata, Lepidosauria). We processed Pleurodeles larvae and Pogona embryos, prepared thin and ultrathin sections of appendicular bones, and analyzed them using light and transmission electron microscopy. We show that static osteogenesis does not precede dynamic osteogenesis in periosteal ossification of Pleurodeles and Pogona. Therefore, the null hypothesis is rejected and according to the parsimony method the ontogenetic sequence observed in the chicken and in the rabbit are convergent. In Pleurodeles and Pogona dynamic osteogenesis occur without a previous rigid mineralized framework, whereas in the chicken and in the rabbit dynamic osteogenesis seems to take place over a mineralized support whether bone (in perichondral ossification) or calcified cartilage (in endochondral ossification). Interestingly, in typical dynamic osteogenesis, osteoblasts show an axis (basal nucleus-distal endoplasmic reticulum) perpendicular to the front of secreted unmineralized bone matrix, whereas in Pleurodeles and Pogona this axis is parallel to the bone matrix.
[Mh] Termos MeSH primário: Osteogênese/fisiologia
Pleurodeles/fisiologia
Répteis/fisiologia
[Mh] Termos MeSH secundário: Animais
Calcificação Fisiológica/fisiologia
Coelhos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170519
[Lr] Data última revisão:
170519
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170202
[St] Status:MEDLINE
[do] DOI:10.1002/jmor.20659


  3 / 459 MEDLINE  
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[PMID]:27358276
[Au] Autor:Karakasiliotis K; Thandiackal R; Melo K; Horvat T; Mahabadi NK; Tsitkov S; Cabelguen JM; Ijspeert AJ
[Ad] Endereço:Biorobotics Laboratory, École Polytechnique Fédérale de Lausanne, 1015 Lausanne, Switzerland.
[Ti] Título:From cineradiography to biorobots: an approach for designing robots to emulate and study animal locomotion.
[So] Source:J R Soc Interface;13(119), 2016 Jun.
[Is] ISSN:1742-5662
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Robots are increasingly used as scientific tools to investigate animal locomotion. However, designing a robot that properly emulates the kinematic and dynamic properties of an animal is difficult because of the complexity of musculoskeletal systems and the limitations of current robotics technology. Here, we propose a design process that combines high-speed cineradiography, optimization, dynamic scaling, three-dimensional printing, high-end servomotors and a tailored dry-suit to construct Pleurobot: a salamander-like robot that closely mimics its biological counterpart, Pleurodeles waltl Our previous robots helped us test and confirm hypotheses on the interaction between the locomotor neuronal networks of the limbs and the spine to generate basic swimming and walking gaits. With Pleurobot, we demonstrate a design process that will enable studies of richer motor skills in salamanders. In particular, we are interested in how these richer motor skills can be obtained by extending our spinal cord models with the addition of more descending pathways and more detailed limb central pattern generator networks. Pleurobot is a dynamically scaled amphibious salamander robot with a large number of actuated degrees of freedom (DOFs: 27 in total). Because of our design process, the robot can capture most of the animal's DOFs and range of motion, especially at the limbs. We demonstrate the robot's abilities by imposing raw kinematic data, extracted from X-ray videos, to the robot's joints for basic locomotor behaviours in water and on land. The robot closely matches the behaviour of the animal in terms of relative forward speeds and lateral displacements. Ground reaction forces during walking also resemble those of the animal. Based on our results, we anticipate that future studies on richer motor skills in salamanders will highly benefit from Pleurobot's design.
[Mh] Termos MeSH primário: Cinerradiografia/métodos
Locomoção
Robótica/métodos
[Mh] Termos MeSH secundário: Animais
Pleurodeles
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171016
[Lr] Data última revisão:
171016
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160701
[St] Status:MEDLINE


  4 / 459 MEDLINE  
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[PMID]:26152687
[Au] Autor:Bour A; Mouchet F; Cadarsi S; Silvestre J; Verneuil L; Baqué D; Chauvet E; Bonzom JM; Pagnout C; Clivot H; Fourquaux I; Tella M; Auffan M; Gauthier L; Pinelli E
[Ad] Endereço:a CNRS, Université de Toulouse, INP, UPS, EcoLab (Laboratoire d'écologie fonctionnelle et environnement) UMR 5245 , ENSAT, Avenue de l'Agrobiopole , Castanet Tolosan , France .
[Ti] Título:Toxicity of CeO2 nanoparticles on a freshwater experimental trophic chain: A study in environmentally relevant conditions through the use of mesocosms.
[So] Source:Nanotoxicology;10(2):245-55, 2016.
[Is] ISSN:1743-5404
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:The toxicity of CeO2 NPs on an experimental freshwater ecosystem was studied in mesocosm, with a focus being placed on the higher trophic level, i.e. the carnivorous amphibian species Pleurodeles waltl. The system comprised species at three trophic levels: (i) bacteria, fungi and diatoms, (ii) Chironomus riparius larvae as primary consumers and (iii) Pleurodeles larvae as secondary consumers. NP contamination consisted of repeated additions of CeO2 NPs over 4 weeks, to obtain a final concentration of 1 mg/L. NPs were found to settle and accumulate in the sediment. No effects were observed on litter decomposition or associated fungal biomass. Changes in bacterial communities were observed from the third week of NP contamination. Morphological changes in CeO2 NPs were observed at the end of the experiment. No toxicity was recorded in chironomids, despite substantial NP accumulation (265.8 ± 14.1 mg Ce/kg). Mortality (35.3 ± 6.8%) and a mean Ce concentration of 13.5 ± 3.9 mg/kg were reported for Pleurodeles. Parallel experiments were performed on Pleurodeles to determine toxicity pathways: no toxicity was observed by direct or dietary exposures, although Ce concentrations almost reached 100 mg/kg. In view of these results, various toxicity mechanisms are proposed and discussed. The toxicity observed on Pleurodeles in mesocosm may be indirect, due to microorganism's interaction with CeO2 NPs, or NP dissolution could have occurred in mesocosm due to the structural complexity of the biological environment, resulting in toxicity to Pleurodeles. This study strongly supports the importance of ecotoxicological assessment of NPs under environmentally relevant conditions, using complex biological systems.
[Mh] Termos MeSH primário: Cério/toxicidade
Ecotoxicologia/métodos
Cadeia Alimentar
Água Doce/microbiologia
Nanopartículas/toxicidade
[Mh] Termos MeSH secundário: Animais
Bactérias/efeitos dos fármacos
Biomassa
Cério/química
Chironomidae/efeitos dos fármacos
Diatomáceas/efeitos dos fármacos
Fungos/efeitos dos fármacos
Larva/efeitos dos fármacos
Nanopartículas/química
Pleurodeles
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
30K4522N6T (Cerium); 619G5K328Y (ceric oxide)
[Em] Mês de entrada:1612
[Cu] Atualização por classe:161230
[Lr] Data última revisão:
161230
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150709
[St] Status:MEDLINE
[do] DOI:10.3109/17435390.2015.1053422


  5 / 459 MEDLINE  
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[PMID]:26638232
[Au] Autor:Markitantova YV; Avdonin PP; Grigoryan EN
[Ti] Título:[Identification of the Gene Encoding Nucleostemin in the Eye Tissues of Pleurodeles waltl].
[So] Source:Izv Akad Nauk Ser Biol;(5):453-60, 2015 Sep-Oct.
[Is] ISSN:1026-3470
[Cp] País de publicação:Russia (Federation)
[La] Idioma:rus
[Ab] Resumo:Nucleotide sequences were identified in the eye tissues (lens, retina, and retinal pigment epithelium) of the adult newt Pleurodeles waltl by the polymerase chain reaction with primers for the Ns gene. Sequencing showed that these nucleotide sequences belong to the Ns gene of the newt P. walt, which encodes the nucleolar protein nucleostemin. Structural analysis revealed a high homology of Ns nucleotide sequences of P. walt! with those of newts. Cynops pyrrhogaster and Notophthalmus viridescens. The expression of the Ns gene of P. walt, identified in the specialized eye cells of adult newts of the studied species, indicates that these differentiated cells retain some of the molecular characteristics inherent to the undifferentiated cells.
[Mh] Termos MeSH primário: Proteínas de Anfíbios
Proteínas do Olho
Proteínas Nucleares
Epitélio Pigmentado da Retina/metabolismo
[Mh] Termos MeSH secundário: Proteínas de Anfíbios/genética
Proteínas de Anfíbios/metabolismo
Animais
Sequência de Bases
Proteínas do Olho/genética
Proteínas do Olho/metabolismo
Dados de Sequência Molecular
Proteínas Nucleares/genética
Proteínas Nucleares/metabolismo
Pleurodeles
[Pt] Tipo de publicação:ENGLISH ABSTRACT; JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Amphibian Proteins); 0 (Eye Proteins); 0 (Nuclear Proteins)
[Em] Mês de entrada:1512
[Cu] Atualização por classe:161020
[Lr] Data última revisão:
161020
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:151208
[St] Status:MEDLINE


  6 / 459 MEDLINE  
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[PMID]:26277106
[Au] Autor:Fonte C; Gruez A; Ghislin S; Frippiat JP
[Ad] Endereço:EA7300, Stress Immunity Pathogens Laboratory, Faculty of Medicine, Université de Lorraine, 9 Avenue de la Forêt de Haye, F-54500, VandÅ“uvre-lès-Nancy, France.
[Ti] Título:The urodele amphibian Pleurodeles waltl has a diverse repertoire of immunoglobulin heavy chains with polyreactive and species-specific features.
[So] Source:Dev Comp Immunol;53(2):371-84, 2015 Dec.
[Is] ISSN:1879-0089
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Urodele amphibians are an interesting model because although they possess the cardinal elements of the vertebrate immune system, their immune response is apparently subdued. This phenomenon, sometimes regarded as a state of immunodeficiency, has been attributed by some authors to limited antibody diversity. We reinvestigated this issue in Pleurodeles waltl, a metamorphosing urodele, and noted that upsilon transcripts of its IgY repertoire were as diverse as alpha transcripts of the mammalian IgA repertoire. Mu transcripts encoding the IgM repertoire were less diverse, but could confer more plasticity. Both isotypes present potential polyreactive features that may confer urodele antibodies with the ability to bind to a variety of antigens. Finally, we observed additional cysteines in CDR1 and 2 of the IGHV5 and IGHV6 domains, some of which specific to urodeles, that could allow the establishment of a disulfide bond between these CDRs. Together, these data suggest that urodele antibody diversity is not as low as previously thought.
[Mh] Termos MeSH primário: Regiões Determinantes de Complementaridade/genética
Cisteína/genética
Cadeias Pesadas de Imunoglobulinas/genética
Pleurodeles/imunologia
[Mh] Termos MeSH secundário: Animais
Diversidade de Anticorpos
Epitopos
Feminino
Regulação da Expressão Gênica no Desenvolvimento
Imunoglobulina A/genética
Imunoglobulina M/genética
Estágios do Ciclo de Vida
Mamíferos
Pleurodeles/crescimento & desenvolvimento
Especificidade da Espécie
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Complementarity Determining Regions); 0 (Epitopes); 0 (Immunoglobulin A); 0 (Immunoglobulin Heavy Chains); 0 (Immunoglobulin M); K848JZ4886 (Cysteine)
[Em] Mês de entrada:1607
[Cu] Atualização por classe:150929
[Lr] Data última revisão:
150929
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150817
[St] Status:MEDLINE


  7 / 459 MEDLINE  
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[PMID]:25740495
[Au] Autor:Hayashi T; Takeuchi T
[Ad] Endereço:Department of Biomedical Sciences, School of Life Science, Faculty of Medicine, Tottori University, 86 Nishi-cho, Yonago, 683-8503, Tottori, Japan, toshi2@med.tottori-u.ac.jp.
[Ti] Título:Gene manipulation for regenerative studies using the Iberian ribbed newt, Pleurodeles waltl.
[So] Source:Methods Mol Biol;1290:297-305, 2015.
[Is] ISSN:1940-6029
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Newts provide a unique model animal for regenerative studies. An experimental model system for molecular genetics in newts is needed in order to clarify the mechanisms of regeneration from the perspective of gene functions. We have identified that Iberian ribbed newt (Pleurodeles waltl) is a suitable model animal for such studies. Here we describe protocols for gene manipulation using Pleurodeles waltl.
[Mh] Termos MeSH primário: Técnicas Genéticas
Pleurodeles/genética
Pleurodeles/fisiologia
Regeneração/genética
[Mh] Termos MeSH secundário: Criação de Animais Domésticos
Animais
Desoxirribonucleases de Sítio Específico do Tipo II/metabolismo
Embrião não Mamífero/metabolismo
Feminino
Técnicas de Transferência de Genes
Engenharia Genética
Vetores Genéticos/genética
Inseminação Artificial
Masculino
Microinjeções
Plasmídeos/genética
RNA Mensageiro/genética
RNA Mensageiro/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (RNA, Messenger); EC 3.1.21.4 (Deoxyribonucleases, Type II Site-Specific)
[Em] Mês de entrada:1511
[Cu] Atualização por classe:150305
[Lr] Data última revisão:
150305
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150306
[St] Status:MEDLINE
[do] DOI:10.1007/978-1-4939-2495-0_23


  8 / 459 MEDLINE  
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[PMID]:25740476
[Au] Autor:Joven A; Kirkham M; Simon A
[Ad] Endereço:Department of Cell and Molecular Biology, Karolinska Institute, Berzelius väg 35, Stockholm, 17177, Sweden, alberto.joven.araus@ki.se.
[Ti] Título:Husbandry of Spanish ribbed newts (Pleurodeles waltl).
[So] Source:Methods Mol Biol;1290:47-70, 2015.
[Is] ISSN:1940-6029
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Research on urodele amphibians, such as newts, is constantly contributing to our understanding of fundamental biological processes. In the present chapter, we present detailed husbandry protocols for the Spanish ribbed newt (Pleurodeles waltl ). We describe the main phases of their life cycle, with emphasis on the progressive development of sensory, motor, and integration systems, which lead to the acquisition of specific stereotyped (and conditioned) behaviors. The methods are outlined to manage housing, feeding, handling, captive breeding, health monitoring, and euthanasia in this species under laboratory conditions. With minor changes, these protocols can also be applied to other species of urodele amphibians commonly used in laboratory research.
[Mh] Termos MeSH primário: Criação de Animais Domésticos/métodos
Pleurodeles
[Mh] Termos MeSH secundário: Doenças dos Animais/terapia
Animais
Cruzamento
Embrião não Mamífero
Eutanásia Animal
Feminino
Fertilização In Vitro
Saúde
Larva
Masculino
Pleurodeles/embriologia
Pleurodeles/microbiologia
Pleurodeles/fisiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1511
[Cu] Atualização por classe:150305
[Lr] Data última revisão:
150305
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150306
[St] Status:MEDLINE
[do] DOI:10.1007/978-1-4939-2495-0_4


  9 / 459 MEDLINE  
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[PMID]:25286122
[Au] Autor:Makanae A; Mitogawa K; Satoh A
[Ad] Endereço:Okayama University, Research Core for Interdisciplinary Sciences (RCIS), 3-1-1, Tsushima-Naka, Kitaku, Okayama 700-8530, Japan.
[Ti] Título:Co-operative Bmp- and Fgf-signaling inputs convert skin wound healing to limb formation in urodele amphibians.
[So] Source:Dev Biol;396(1):57-66, 2014 Dec 01.
[Is] ISSN:1095-564X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Urodele amphibians have remarkable organ regeneration capability, and their limb regeneration capability has been investigated as a representative phenomenon. In the early 19th century, nerves were reported to be an essential tissue for the successful induction of limb regeneration. Nerve substances that function in the induction of limb regeneration responses have long been sought. A new experimental system called the accessory limb model (ALM) has been established to identify the nerve factors. Skin wounding in urodele amphibians results in skin wound healing but never in limb induction. However, nerve deviation to the wounded skin induces limb formation in ALM. Thus, nerves can be considered to have the ability to transform skin wound healing to limb formation. In the present study, co-operative Bmp and Fgf application, instead of nerve deviation, to wounded skin transformed skin wound healing to limb formation in two urodele amphibians, axolotl (Ambystoma mexicanum) and newt (Pleurodeles waltl). Our findings demonstrate that defined factors can induce homeotic transformation in postembryonic bodies of urodele amphibians. The combination of Bmp and Fgf(s) may contribute to the development of novel treatments for organ regeneration.
[Mh] Termos MeSH primário: Proteínas Morfogenéticas Ósseas/metabolismo
Extremidades/fisiologia
Fatores de Crescimento de Fibroblastos/metabolismo
Regulação da Expressão Gênica no Desenvolvimento
Pele/metabolismo
Cicatrização
[Mh] Termos MeSH secundário: Ambystoma mexicanum
Animais
Gânglios Espinais/fisiologia
Hibridização In Situ
Tecido Nervoso/fisiologia
Neurônios/fisiologia
Pleurodeles
Regeneração
Transdução de Sinais
Pele/inervação
Fatores de Tempo
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Bone Morphogenetic Proteins); 62031-54-3 (Fibroblast Growth Factors)
[Em] Mês de entrada:1502
[Cu] Atualização por classe:141203
[Lr] Data última revisão:
141203
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:141007
[St] Status:MEDLINE


  10 / 459 MEDLINE  
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[PMID]:24895174
[Au] Autor:Quilhac A; de Ricqlès A; Lamrous H; Zylberberg L
[Ad] Endereço:Sorbonne Universités, UPMC Univ Paris 06, UMR 7193, Institut des Sciences de la Terre Paris (ISTeP), Equipe Biominéralisations et Environnements Sédimentaires, F-75005, Paris, France; CNRS, UMR 7193, Institut des Sciences de la Terre Paris (ISTeP), F-75005, Paris, France.
[Ti] Título:Globuli ossei in the long limb bones of Pleurodeles waltl (Amphibia, Urodela, Salamandridae).
[So] Source:J Morphol;275(11):1226-37, 2014 Nov.
[Is] ISSN:1097-4687
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:To date, little is known about the structure of the cells and the fibrillar matrix of the globuli ossei, globular structures showing histochemical properties of an osseous tissue, sometimes found in the resorption front of the hypertrophied cartilage in many tetrapods, and easily observed in the long bones of the Urodele Pleurodeles waltl. Here, we present the results obtained from the appendicular long bones of metamorphosed juveniles and subadults using histological and histochemical methods and transmission electron microscopy. The distal part of the cone-shaped cartilage contains a heterogeneous cell population composed of the typical "light" hypertrophic chondrocytes and scarce "dark" hypertrophic chondrocytes. The "dark" chondrocytes display ultrastructural characteristics suggesting that they probably undergo degeneration through chondroptosis. However, in the hypertrophic, calcified cartilage close to the erosion front by the marrow, several noninvaded chondrocytic lacunae retained cells that do not show any morphological characteristics of degeneration and that cannot be identified as regular chondrocytes or osteocytes. These modified chondrocytes that have lost their regular morphology, appear to be active in the terminal cartilage and synthesize collagen fibrils of a peculiar diameter intermediate between the Type I collagen found in bone and the Type II collagen characteristic of cartilage. It is suggested that the local occurrence of globuli ossei is linked to a low rate of longitudinal growth as is the case in the long bones of postmetamorphic urodeles.
[Mh] Termos MeSH primário: Osso e Ossos/anatomia & histologia
Condrócitos/ultraestrutura
Lâmina de Crescimento/ultraestrutura
Cartilagem Hialina/ultraestrutura
Osteócitos/ultraestrutura
Pleurodeles/anatomia & histologia
[Mh] Termos MeSH secundário: Animais
Desenvolvimento Ósseo
Diferenciação Celular
Matriz Extracelular
Extremidades/anatomia & histologia
Hipertrofia
Microscopia Eletrônica de Transmissão
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1412
[Cu] Atualização por classe:141011
[Lr] Data última revisão:
141011
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:140605
[St] Status:MEDLINE
[do] DOI:10.1002/jmor.20296



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BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde