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Pesquisa : B01.050.150.900.493.200.244 [Categoria DeCS]
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[PMID]:29274208
[Au] Autor:Ardalan NM; Al-Hashimi SF; Garhy M; Hamdi SAH; Al Ghamdi A; Morsy K
[Ad] Endereço:Department of Biology, College of Science for Woman, University of Baghdad, Mohamed Al-Qasim St., 10071, Baghdad, Iraq
[Ti] Título:The light microscopy and ultrastructural characteristics of Myxobolus naffari (Myxosporea, Myxobolidae) infecting the Nile carp Labeo niloticus (Cyprinidae) and its histological impact
[So] Source:Ann Parasitol;63(3):159-165, 2017.
[Is] ISSN:2299-0631
[Cp] País de publicação:Poland
[La] Idioma:eng
[Ab] Resumo:During a survey of myxosporean parasites infecting freshwater fishes from the River Nile at Giza Governorates, Egypt between March and September 2016, nine out of 30 specimens of the Nile carp Labeo niloticus (Cyprinidae) were found to be naturally infected with Myxobolus naffari (Myxobolidae). Small macroscopic plasmodia appeared embedded in the host gill tissue accompanied with fusion of the gill epithelia, and atrophy was observed at the site of infection. The host reaction was manifested by the encapsulation of the plasmodia with a thick layer of connective tissue. The plasmodia appeared as white, elongated rods between gill filaments with an intensity ranging from three to eight cysts/fish. The average dimensions of plasmodia were 1.2­2.0 (1.8 ± 0.2) mm long × 0.4­0.7 (0.6 ± 0.2) mm wide. The spores were oval, reaching 9.56­11.2 (10.2 ± 0.2) µm long and 6.5­7.7 (7.0 ± 0.4) µm wide with two equal-sized polar capsules regularly arranged at the anterior pole of each spore. They were 4.51­5.5 (5.1 ± 0.4) µm in length and 1.5­2.0 (1.7 ± 0.2) µm in width. Histological, semi-thin sections were taken through parasite plasmodia and transmission electron microscopic examination of ultrathin sections was performed to describe the developmental stages of the recorded parasite within the host fish.
[Mh] Termos MeSH primário: Cyprinidae/parasitologia
Doenças dos Peixes/parasitologia
Myxobolus/ultraestrutura
Doenças Parasitárias em Animais/parasitologia
[Mh] Termos MeSH secundário: Animais
Egito/epidemiologia
Doenças dos Peixes/epidemiologia
Doenças Parasitárias em Animais/epidemiologia
Rios
Esporos/ultraestrutura
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180305
[Lr] Data última revisão:
180305
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171224
[St] Status:MEDLINE
[do] DOI:10.17420/ap6303.101


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[PMID]:29360868
[Au] Autor:Kitanishi S; Onikura N; Mukai T
[Ad] Endereço:Faculty of Regional Studies, Gifu University, Gifu, Japan.
[Ti] Título:A simple SNP genotyping method reveals extreme invasions of non-native haplotypes in pale chub Opsariichthys platypus, a common cyprinid fish in Japan.
[So] Source:PLoS One;13(1):e0191731, 2018.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Biological invasion by non-native subspecies or populations is one of the most serious threats to ecosystems, because these species might be easily established in the introduced area and can negatively affect native populations through competition and hybridization. Pale chub Opsariichthys platypus, one of the most common fish in East Asia, exhibits clear genetic differentiation among regional populations; however, introgression and subsequent loss of genetic integrity have been occurring throughout Japan due to the artificial introduction of non-native conspecifics. In this study, we developed a simple SNP genotyping method to discriminate between native and non-native mitochondrial DNA (mtDNA) haplotypes in pale chub using real-time PCR assay. We then investigated the distribution patterns of non-native pale chub in Tokai region, located in the center of Honshu Island, Japan and developed a predictive model of the occurrence of non-natives to reveal the factors influencing their invasion. The specificity and accuracy of the genotyping method were confirmed by using samples whose haplotypes were determined previously. Extensive occurrence of non-native haplotypes in Tokai region was detected by this method. In addition, our models suggested that the presence of non-natives varied greatly depending on the river system, and was positively influenced by the impounded water areas. Our method could accurately distinguish between native and non-native haplotypes of pale chub in Japan and suggested key environmental factors associated with the presence of non-natives. This approach can greatly reduce experimental costs be a great contribution for quantitative investigation.
[Mh] Termos MeSH primário: Cyprinidae/genética
Haplótipos
Polimorfismo de Nucleotídeo Único
[Mh] Termos MeSH secundário: Animais
Genótipo
Japão
Modelos Teóricos
Reação em Cadeia da Polimerase em Tempo Real
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T; VALIDATION STUDIES
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180226
[Lr] Data última revisão:
180226
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180124
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0191731


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[PMID]:29339070
[Au] Autor:Wang R; Li Y; Zhou Z; Liu Q; Zeng L; Xiao T
[Ad] Endereço:Hunan Engineering Technology Research Center of Featured Aquatic Resources Utilization, Hunan Agricultural University, Changsha 410128, China; College of Life and Environment Sciences, Hunan University of Arts and Science, Changde, Hunan 415000, China.
[Ti] Título:Involvement of interferon regulatory factor 3 from the barbel chub Squaliobarbus curriculus in the immune response against grass carp reovirus.
[So] Source:Gene;648:5-11, 2018 Mar 30.
[Is] ISSN:1879-0038
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:The barbel chub Squaliobarbus curriculus is an important commercial fish species in China, and has shown significant resistance to grass carp reovirus (GCRV). In this study, the cDNA sequence of interferon regulatory factors 3 (IRF3) from Squaliobarbus curriculus, designated as ScIRF3, was cloned, and its effect against GCRV was investigated. The full-length 1837 base pair (bp) cDNA of ScIRF3 contained a complete open reading frame of 1374 bp and encoded a putative polypeptide of 457 amino acid residues. The ScIRF3 protein contained conserved domains, including an N-terminal DNA-binding domain, a C-terminal IRF association domain, and a serine-rich domain. Phylogenetic analysis showed that ScIRF3 was closely clustered with IRF3s from Carassius auratus and Ctenopharyngodon idellus. Quantitative real-time polymerase chain reaction analysis showed that the expression levels of ScIRF3 in Squaliobarbus curriculus were the highest in the spleen and lowest in the muscle. After GCRV infection, expression levels of both ScIRF3 and type I interferon (IFN) were initially up-regulated and subsequently down-regulated in the spleen and intestine. Correlation analysis showed that the expression level of type I IFN is significantly positively correlated with that of ScIRF3 (Pearson correlation coefficient: 0.883, P: 0.004) in the intestine. The expression level of type I IFN was also significantly up-regulated and the GCRV titer was significantly decreased (P < .05) in GCRV-infected ScIRF3-overexpressing Ctenopharyngodon idellus kidney cells. These results indicate that ScIRF3 may play a role in the type I IFN immune response against GCRV in Squaliobarbus curriculus and can also inhibit GCRV replication in Ctenopharyngodon idellus kidney cells.
[Mh] Termos MeSH primário: Cyprinidae/imunologia
Doenças dos Peixes/imunologia
Proteínas de Peixes/imunologia
Fator Regulador 3 de Interferon/imunologia
Reoviridae/imunologia
[Mh] Termos MeSH secundário: Sequência de Aminoácidos
Animais
Cyprinidae/metabolismo
Cyprinidae/virologia
Doenças dos Peixes/metabolismo
Doenças dos Peixes/virologia
Proteínas de Peixes/classificação
Proteínas de Peixes/metabolismo
Perfilação da Expressão Gênica/métodos
Interações Hospedeiro-Patógeno/imunologia
Fator Regulador 3 de Interferon/genética
Fator Regulador 3 de Interferon/metabolismo
Interferon Tipo I/genética
Interferon Tipo I/imunologia
Interferon Tipo I/metabolismo
Filogenia
Reoviridae/fisiologia
Homologia de Sequência de Aminoácidos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Fish Proteins); 0 (Interferon Regulatory Factor-3); 0 (Interferon Type I)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180226
[Lr] Data última revisão:
180226
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180118
[St] Status:MEDLINE


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[PMID]:29251851
[Au] Autor:Kumbar SM; Lad SB
[Ti] Título:Estimation of age and longevity of freshwater fish Salmophasia balookee from otoliths, scales and vertebrae.
[So] Source:J Environ Biol;37(5):943-7, 2016 09.
[Is] ISSN:0254-8704
[Cp] País de publicação:India
[La] Idioma:eng
[Mh] Termos MeSH primário: Envelhecimento/fisiologia
Escamas de Animais/crescimento & desenvolvimento
Cyprinidae/fisiologia
Longevidade/fisiologia
Membrana dos Otólitos/crescimento & desenvolvimento
Coluna Vertebral/anatomia & histologia
[Mh] Termos MeSH secundário: Animais
Coluna Vertebral/crescimento & desenvolvimento
[Pt] Tipo de publicação:RESEARCH SUPPORT, NON-U.S. GOV'T; JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180222
[Lr] Data última revisão:
180222
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171219
[St] Status:MEDLINE


  5 / 7556 MEDLINE  
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[PMID]:29257630
[Au] Autor:Saylor Ö
[Ti] Título:Toxic effects of permethrin on Pseudorasbora parva.
[So] Source:J Environ Biol;37(6):1247-53, 2016 Nov.
[Is] ISSN:0254-8704
[Cp] País de publicação:India
[La] Idioma:eng
[Ab] Resumo:The present study deals with acute toxicity and hematological, histopathological and genotoxical effects of permethrin, a synthetic pyrethroid, on Pseudorasbora parva. Acute toxicity of 96-hrs LC50 value was found to be 88.25 (84.60-92.63) µgl-1. Sublethal dose was taken as 8.82 µgl-1 (the 1/10 of the LC50 value) in bio-experiments. Micronucleus changes in blood erythrocyte and hemotocyte level in P. parva exposed to sub-lethal concentration were investigated. Difference between nucleolus abnormalities in the experimental and control group was found to be statistically significant (t-test). Micronucleus frequency was found to be 8.26. The hematocrit level in control and experimental groups were found to be 24.43% and 14.673%. No pathological symptoms were observed in the muscle of P. parva exposed to sublethal dose for 96 hrs. Pathological symptoms observed after 96 hours from permethrin administration in other organs were: Fusion, Telangiectasis, epithelial lifting and hyperemia in gills; hydropic degeneration, lipid degeneration and passive hyperemia in liver and enlargement of cavum glomeruli and Bowman space in kidneys and hemorrhage, edema and hyperemia in brain, respectively.
[Mh] Termos MeSH primário: Cyprinidae
Inseticidas/toxicidade
Permetrina/toxicidade
Poluentes Químicos da Água/toxicidade
[Mh] Termos MeSH secundário: Animais
Encéfalo/efeitos dos fármacos
Encéfalo/patologia
Brânquias/efeitos dos fármacos
Brânquias/patologia
Espécies Introduzidas
Rim/efeitos dos fármacos
Rim/patologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Insecticides); 0 (Water Pollutants, Chemical); 509F88P9SZ (Permethrin)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180219
[Lr] Data última revisão:
180219
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171220
[St] Status:MEDLINE


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[PMID]:29372806
[Au] Autor:Slynko YV; Slynko EE; Karpova EP; Boltachev AR
[Ti] Título:[Genetic variation of the mtDNA cyt b locus in topmouth gudgeon introduced into water bodies in the northern part of the Black Sea region].
[So] Source:Genetika;53(1):79-87, 2017 Jan.
[Is] ISSN:0016-6758
[Cp] País de publicação:Russia (Federation)
[La] Idioma:rus
[Ab] Resumo:The up-to-date phylogeographical distribution of the topmouth gudgeon Pseudorasbora parva Temminck et Schlegel 1846 in water bodies of the Northern Black Sea region is considered. Genetic variation of mtDNA cyt b gene is analyzed. It is established that topmouth gudgeon penetrated and spread in the basins of the Dnieper and Don rivers and in water bodies of Crimea from the secondary center of its dispersion­ water bodies of Central Europe. It is demonstrated that haplotypes of topmouth gudgeon in the Danube delta are the most homologous to the haplotypes in the native range of the species in China. A considerable decrease in the level of genetic variation in the populations in the Black Sea region is reported.
[Mh] Termos MeSH primário: Cyprinidae/genética
Citocromos b/genética
DNA Mitocondrial/genética
Proteínas de Peixes/genética
Variação Genética
Proteínas Mitocondriais/genética
[Mh] Termos MeSH secundário: Animais
Mar Negro
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (DNA, Mitochondrial); 0 (Fish Proteins); 0 (Mitochondrial Proteins); 9035-37-4 (Cytochromes b)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180216
[Lr] Data última revisão:
180216
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180127
[St] Status:MEDLINE


  7 / 7556 MEDLINE  
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[PMID]:29368907
[Au] Autor:Singh AK; Kumar R; Mishra AK; Singh M; Baisvar VS; Chauhan UK; Kushwaha B; Nagpure NS
[Ti] Título:Authentication of five Barilius species from Indian waters using DNA barcoding.
[So] Source:Genetika;52(8):943-50, 2016 Aug.
[Is] ISSN:0016-6758
[Cp] País de publicação:Russia (Federation)
[La] Idioma:eng
[Ab] Resumo:Authentic identification of fish species is essential for conserving them as a valuable genetic resource in our environment. DNA barcoding of living beings has become an important and ultimate tool for establishing their molecular identity. Among cyprinids, Barilius is an important genus having nearly 23 species in Indian region whose morphological identification is often difficult due to minute differences in their features. Five species collected from Indian waters and primarily identified as Opsarius bakeri (syn. Barilius bakeri), B. gatensis, B. vagra, B. bendelisis and B. ngawa were authenticated by their DNA barcoding based on mitochondrial COI gene sequences. Five individuals of each species were taken for barcode preparation by COI gene sequencing which yielded one barcode for B. ngawa, two barcodes each for O. bakeri, B. gatensis, B. bendelisis and three barcodes for B. vagra. The order of inter and intra-specific variation was estimated to know a preliminary status of variation prevailing in these cold stream fish species significant for evolution and conservation of these valued species of our ichthyofauna. Average variation within genera was found to be 13.6% with intra-specific variation ranging from 0.0% (B. ngawa) to 0.6% (B. gatensis). These distance data are in the same order found by various researchers globally using COI barcode sequences in different fish species. Phylogenetic relatedness among Barilius species and some other cyprinids validate their status of individual species as established by conventional taxonomy.
[Mh] Termos MeSH primário: Cyprinidae
Código de Barras de DNA Taxonômico
DNA Mitocondrial/genética
Complexo IV da Cadeia de Transporte de Elétrons/genética
Proteínas de Peixes/genética
[Mh] Termos MeSH secundário: Animais
Cyprinidae/classificação
Cyprinidae/genética
Índia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (DNA, Mitochondrial); 0 (Fish Proteins); EC 1.9.3.1 (Electron Transport Complex IV)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180205
[Lr] Data última revisão:
180205
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180126
[St] Status:MEDLINE


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[PMID]:28747533
[Au] Autor:Nilsson PA; Hulthén K; Chapman BB; Hansson LA; Brodersen J; Baktoft H; Vinterstare J; Brönmark C; Skov C
[Ad] Endereço:Department of Biology-Aquatic Ecology, Lund University, Ecology Building, Lund, Sweden anders.nilsson@biol.lu.se.
[Ti] Título:Species integrity enhanced by a predation cost to hybrids in the wild.
[So] Source:Biol Lett;13(7), 2017 07.
[Is] ISSN:1744-957X
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Species integrity can be challenged, and even eroded, if closely related species can hybridize and produce fertile offspring of comparable fitness to that of parental species. The maintenance of newly diverged or closely related species therefore hinges on the establishment and effectiveness of pre- and/or post-zygotic reproductive barriers. Ecological selection, including predation, is often presumed to contribute to reduced hybrid fitness, but field evidence for a predation cost to hybridization remains elusive. Here we provide proof-of-concept for predation on hybrids being a postzygotic barrier to gene flow in the wild. Cyprinid fishes commonly produce fertile, viable hybrid offspring and therefore make excellent study organisms to investigate ecological costs to hybrids. We electronically tagged two freshwater cyprinid fish species (roach and bream ) and their hybrids in 2005. Tagged fish were returned to their lake of origin, exposing them to natural predation risk from apex avian predators (great cormorant, ). Scanning for regurgitated tags under cormorant roosts 3-4 years later identified cormorant-killed individual fish and allowed us to directly test for a predation cost to hybrids in the wild. Hybrid individuals were found significantly more susceptible to cormorant predation than individuals from either parental species. Such ecological selection against hybrids contributes to species integrity, and can enhance species diversification.
[Mh] Termos MeSH primário: Comportamento Predatório
[Mh] Termos MeSH secundário: Animais
Aves
Cyprinidae
Hibridização Genética
Lagos
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1712
[Cu] Atualização por classe:180204
[Lr] Data última revisão:
180204
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170728
[St] Status:MEDLINE


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[PMID]:28986080
[Au] Autor:Kellock KA; Moore AP; Bringolf RB
[Ad] Endereço:Warnell School of Forestry and Natural Resources, Interdisciplinary Toxicology Program, University of Georgia, 180 E. Green St., Athens, GA, USA.
[Ti] Título:Chronic nitrate exposure alters reproductive physiology in fathead minnows.
[So] Source:Environ Pollut;232:322-328, 2018 Jan.
[Is] ISSN:1873-6424
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Nitrate is a ubiquitous aquatic pollutant that is commonly associated with eutrophication and dead zones in estuaries around the world. At high concentrations nitrate is toxic to aquatic life but at environmental concentrations it has also been purported as an endocrine disruptor in fish. To investigate the potential for nitrate to cause endocrine disruption in fish, we conducted a lifecycle study with fathead minnows (Pimephales promelas) exposed to nitrate (0, 11.3, and 56.5 mg/L (total nitrate-nitrogen (NO -N)) from <24 h post hatch to sexual maturity (209 days). Body mass, condition factor, gonadal somatic index (GSI), incidence of intersex, and vitellogenin induction were determined in mature male and female fish and plasma 11-keto testosterone (11-KT) was measured in males only. In nitrate-exposed males both 11-KT and vitellogenin were significantly induced when compared with controls. No significant differences occurred for body mass, condition factor, or GSI among males and intersex was not observed in any of the nitrate treatments. Nitrate-exposed females also had significant increases in vitellogenin compared to controls but no significant differences for mass, condition factor, or GSI were observed in nitrate exposed groups. Estradiol was used as a positive control for vitellogenin induction. Our findings suggest that environmentally relevant nitrate levels may disrupt steroid hormone synthesis and/or metabolism in male and female fish and may have implications for fish reproduction, watershed management, and regulation of nutrient pollution.
[Mh] Termos MeSH primário: Cyprinidae/fisiologia
Nitratos/toxicidade
Poluentes Químicos da Água/toxicidade
[Mh] Termos MeSH secundário: Animais
Cyprinidae/metabolismo
Disruptores Endócrinos/toxicidade
Estradiol/sangue
Feminino
Gônadas/efeitos dos fármacos
Masculino
Reprodução/efeitos dos fármacos
Reprodução/fisiologia
Testosterona/análogos & derivados
Testes de Toxicidade Crônica
Vitelogeninas/sangue
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Endocrine Disruptors); 0 (Nitrates); 0 (Vitellogenins); 0 (Water Pollutants, Chemical); 3XMK78S47O (Testosterone); 4TI98Z838E (Estradiol); KF38W1A85U (11-ketotestosterone)
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180122
[Lr] Data última revisão:
180122
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171008
[St] Status:MEDLINE


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[PMID]:28743461
[Au] Autor:Liu XH; Wang ZJ; Jin L; Huang J; Pu DY; Wang DS; Zhang YG
[Ad] Endereço:Key Laboratory of Freshwater Fish Reproduction and Development (Ministry of Education), Key Laboratory of Aquatic Science of Chongqing, Southwest University School of Life Sciences, Chongqing 400715, China.
[Ti] Título:Effects of subchronic exposure to waterborne cadmium on H-P-I axis hormones and related genes in rare minnows (Gobiocypris rarus).
[So] Source:Comp Biochem Physiol C Toxicol Pharmacol;202:1-11, 2017 Nov.
[Is] ISSN:1532-0456
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The H (hypothalamic)-P (pituitary)-I (interrenal) axis is critical in the stress response and other activities of fish. To further investigate cadmium (Cd) toxicity on the H-P-I axis and to identify its potential regulatory genes in fish, the adult female rare minnows (Gobiocypris rarus) were exposed to subchronic (5weeks) levels of waterborne Cd in the present study. This kind of treatment caused dose-dependent decline in fish growth, with significance in the high dose group (100µg/L). Correspondingly, low dose (5-50µg/L) waterborne Cd disrupted the endocrine system of H-P-I axis just at the secretion level, while high dose Cd disrupted both the secretion and synthesis of cortisol and its downstream signals in rare minnows, revealed by the significantly upregulation and positive correlation of corticosteroidogenic genes including MC2R, StAR, CYP11A1, and CYP11B1 in the kidney (including the interrenal tissue) (P<0.05), and the significant alteration of Glcci1, Hsp90AA and Hsp90AB in the hepatopancreas, gill and intestine as well (P<0.05). The expression of Glcci1 was significantly decreased in hepatopancreas, gill and intestine of tested fish following treatment, and its positive correlation with GR (Glucocorticoid receptor) suggested its potential regulation on the cortisol and/or H-P-I axis in fish. The expression of FKBP5 in the intestine was positively and significantly correlated with that of Hsp90AA (P<0.05), and the Hsp90AB transcript in the hepatopancreas was positively correlated with that of Hsp90AA (P<0.05), which indicated that Hsp90AA and Hsp90AB were more likely to serve as cofactors of GR and FKBP5 in response to Cd exposure.
[Mh] Termos MeSH primário: Cloreto de Cádmio/toxicidade
Cyprinidae/fisiologia
Sistema Hipotálamo-Hipofisário/efeitos dos fármacos
Glândula Inter-Renal/efeitos dos fármacos
[Mh] Termos MeSH secundário: Hormônio Adrenocorticotrópico/genética
Hormônio Adrenocorticotrópico/metabolismo
Animais
Cloreto de Cádmio/administração & dosagem
Hormônio Liberador da Corticotropina/genética
Hormônio Liberador da Corticotropina/metabolismo
Esquema de Medicação
Feminino
Regulação da Expressão Gênica/efeitos dos fármacos
Hidrocortisona/genética
Hidrocortisona/metabolismo
Sistema Hipotálamo-Hipofisário/fisiologia
Glândula Inter-Renal/fisiologia
Hormônios Estimuladores de Melanócitos/genética
Hormônios Estimuladores de Melanócitos/metabolismo
RNA Mensageiro/genética
RNA Mensageiro/metabolismo
Proteínas de Ligação a Tacrolimo/genética
Proteínas de Ligação a Tacrolimo/metabolismo
Poluentes Químicos da Água/toxicidade
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (RNA, Messenger); 0 (Water Pollutants, Chemical); 9002-60-2 (Adrenocorticotropic Hormone); 9002-79-3 (Melanocyte-Stimulating Hormones); 9015-71-8 (Corticotropin-Releasing Hormone); EC 5.2.1.- (Tacrolimus Binding Proteins); J6K4F9V3BA (Cadmium Chloride); WI4X0X7BPJ (Hydrocortisone)
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180109
[Lr] Data última revisão:
180109
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170727
[St] Status:MEDLINE



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